Paul Englund
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American biochemist
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Paul Englundbiology Degrees
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Biology
Paul Englund's Degrees
- PhD Biochemistry University of California, Berkeley
- Bachelors Chemistry University of California, Berkeley
Why Is Paul Englund Influential?
(Suggest an Edit or Addition)According to Wikipedia, Paul Theodore Englund was an American biochemist known for his work with parasites, and especially his research into the genetic material in the parasitic organisms that cause African trypanosomiasis, more commonly called sleeping sickness.
Paul Englund's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The Genome Sequence of Trypanosoma cruzi, Etiologic Agent of Chagas Disease (2005) (1341)
- Inhibition of Trypanosoma brucei Gene Expression by RNA Interference Using an Integratable Vector with Opposing T7 Promoters* (2000) (560)
- The structure and biosynthesis of glycosyl phosphatidylinositol protein anchors. (1993) (503)
- Bent helical structure in kinetoplast DNA. (1982) (456)
- The structure and replication of kinetoplast DNA. (1995) (383)
- Enzymatic synthesis of deoxyribonucleic acid. XXVI. Physical and chemical studies of a homogeneous deoxyribonucleic acid polymerase. (1969) (317)
- A homogeneous type II DNA topoisomerase from HeLa cell nuclei. (1981) (315)
- Kinetoplast DNA Network: Evolution of an Improbable Structure (2002) (291)
- Fellowship of the rings: the replication of kinetoplast DNA. (2005) (260)
- A novel pathway for glycan assembly: Biosynthesis of the glycosyl-phosphatidylinositol anchor of the trypanosome variant surface glycoprotein (1989) (245)
- A glycan-phosphatidylinositol-specific phospholipase D in human serum. (1987) (210)
- Selective cleavage of kinetoplast DNA minicircles promoted by antitrypanosomal drugs. (1990) (210)
- Network news: the replication of kinetoplast DNA. (2012) (201)
- The molecular biology of trypanosomes. (1982) (200)
- Visualization of the bent helix in kinetoplast DNA by electron microscopy (1986) (180)
- Enzymatic synthesis of deoxyribonucleic acid. XXX. Binding of triphosphates to deoxyribonucleic acid polymerase. (1969) (180)
- The surface coat of procyclic Trypanosoma brucei: programmed expression and proteolytic cleavage of procyclin in the tsetse fly. (2001) (167)
- Glycolysis modulates trypanosome glycoprotein expression as revealed by an RNAi library (2002) (161)
- Fatty acid remodeling: A novel reaction sequence in the biosynthesis of trypanosome glycosyl phosphatidylinositol membrane anchors (1990) (156)
- A phospholipase C from Trypanosoma brucei which selectively cleaves the glycolipid on the variant surface glycoprotein. (1986) (155)
- Decatenation of kinetoplast DNA by topoisomerases. (1980) (151)
- Fatty Acid Synthesis by Elongases in Trypanosomes (2006) (148)
- RNA interference of a trypanosome topoisomerase II causes progressive loss of mitochondrial DNA (2001) (144)
- The topology of the kinetoplast DNA network (1995) (141)
- Biosynthesis of glycosyl phosphatidylinositol membrane anchors. (1990) (131)
- Rapid processing of the carboxyl terminus of a trypanosome variant surface glycoprotein. (1985) (131)
- A fatty-acid synthesis mechanism specialized for parasitism (2007) (130)
- Multiple mitochondrial DNA polymerases in Trypanosoma brucei. (2002) (129)
- In situ hybridization to the crithidia fasciculata kinetoplast reveals two antipodal sites involved in kinetoplast DNA replication (1992) (129)
- The replication of kinetoplast DNA networks in Crithidia fasciculata (1978) (127)
- Biosynthesis of the glycosyl phosphatidylinositol membrane anchor of the trypanosome variant surface glycoprotein. Origin of the non-acetylated glucosamine. (1989) (126)
- Specialized fatty acid synthesis in African trypanosomes: myristate for GPI anchors. (2000) (124)
- Posttranslational modification and intracellular transport of a trypanosome variant surface glycoprotein (1986) (116)
- Mitochondrial Fatty Acid Synthesis in Trypanosoma brucei* (2007) (107)
- Identification of a glycolipid precursor of the Trypanosoma brucei variant surface glycoprotein. (1986) (105)
- Replication of kinetoplast DNA in trypanosomes. (1988) (102)
- Physical characterization of a kinetoplast DNA fragment with unusual properties. (1984) (99)
- Studies on ficin. I. Its isolation and characterization. (1968) (99)
- Free minicircles of kinetoplast DNA in Crithidia fasciculata. (1979) (94)
- Biosynthesis of a variant surface glycoprotein of Trypanosoma brucei. Processing of the glycolipid membrane anchor and N-linked oligosaccharides. (1988) (89)
- A highly bent fragment of Crithidia fasciculata kinetoplast DNA. (1986) (86)
- p166, a link between the trypanosome mitochondrial DNA and flagellum, mediates genome segregation (2008) (85)
- Purification and properties of the deoxyribonucleic acid polymerase induced by vaccinia virus. (1979) (85)
- The attachment of minicircles to kinetoplast DNA networks during replication (1993) (84)
- Multiple procyclin isoforms are expressed differentially during the development of insect forms of Trypanosoma brucei. (2001) (78)
- Fatty acid synthesis in African trypanosomes: a solution to the myristate mystery. (2001) (77)
- Specific labeling of 3' termini with T4 DNA polymerase. (1980) (77)
- Intramitochondrial Location and Dynamics of Crithidia fasciculata Kinetoplast Minicircle Replication Intermediates (2001) (75)
- Trypanosoma brucei Has Two Distinct Mitochondrial DNA Polymerase β Enzymes* (2003) (75)
- The Kinetoplast Duplication Cycle in Trypanosoma brucei Is Orchestrated by Cytoskeleton-Mediated Cell Morphogenesis (2010) (74)
- The Killing of African Trypanosomes by Ethidium Bromide (2010) (73)
- The Adenosine Analog Tubercidin Inhibits Glycolysis in Trypanosoma brucei as Revealed by an RNA Interference Library* (2003) (70)
- An analog of myristic acid with selective toxicity for African trypanosomes. (1991) (70)
- Replication of kinetoplast DNA: an update for the new millennium. (2001) (69)
- Mitochondrial fatty acid synthesis is required for normal mitochondrial morphology and function in Trypanosoma brucei (2008) (68)
- A DNA Polymerase β in the Mitochondrion of the Trypanosomatid Crithidia fasciculata(*) (1995) (67)
- Identification of a Bacterial-Like HslVU Protease in the Mitochondria of Trypanosoma brucei and Its Role in Mitochondrial DNA Replication (2008) (66)
- The 3'-terminal nucleotide sequences of T7 DNA. (1972) (66)
- Intramitochondrial Localization of Universal Minicircle Sequence-Binding Protein, a Trypanosomatid Protein That Binds Kinetoplast Minicircle Replication Origins (2001) (65)
- A bent helix in kinetoplast DNA. (1983) (65)
- The structure of replicating kinetoplast DNA networks (1993) (64)
- Drug-promoted cleavage of kinetoplast DNA minicircles. Evidence for type II topoisomerase activity in trypanosome mitochondria. (1989) (63)
- A gap at a unique location in newly replicated kinetoplast DNA minicircles from Trypanosoma equiperdum. (1985) (62)
- Trypanosomes have six mitochondrial DNA helicases with one controlling kinetoplast maxicircle replication. (2009) (62)
- Mitochondrial origin-binding protein UMSBP mediates DNA replication and segregation in trypanosomes (2007) (61)
- Replication of kinetoplast DNA maxicircles (1984) (60)
- The replication mechanism of kinetoplast DNA networks in several trypanosomatid species. (1998) (60)
- A Trypanosome Mitochondrial RNA Polymerase Is Required for Transcription and Replication* (2002) (59)
- Role of p38 in Replication of Trypanosoma brucei Kinetoplast DNA (2006) (56)
- Enzymatic synthesis of deoxyribonucleic acid. XXVII. Chemical modifications of deoxyribonucleic acid polymerase. (1969) (56)
- The effect of template secondary structure on vaccinia DNA polymerase. (1979) (56)
- Analysis of nucleotide sequences at 3' termini of duplex deoxyribonucleic acid with the use of the T4 deoxyribonucleic acid polymerase. (1971) (55)
- The major cell surface glycoprotein procyclin is a receptor for induction of a novel form of cell death in African trypanosomes in vitro. (2000) (54)
- Kinetoplast DNA replication: mechanistic differences between Trypanosoma brucei and Crithidia fasciculata (1994) (54)
- The absence of supercoiling in kinetoplast DNA minicircles. (1993) (52)
- Intermediates in the replication of kinetoplast DNA minicircles. (1985) (51)
- Two distinct forms of surface antigen gene rearrangement in Trypanosoma brucei (1982) (51)
- RNA interference for analysis of gene function in trypanosomatids. (2004) (51)
- Trypanosoma brucei has two distinct mitochondrial DNA polymerase beta enzymes. (2003) (51)
- What happens when Trypanosoma brucei leaves Africa. (2008) (50)
- Lyme disease and human babesiosis: evidence incriminating vector and reservoir hosts. (1988) (50)
- Enzymatic synthesis of deoxyribonucleic acid. XXXI. Binding of deoxyribonucleic acid to deoxyribonucleic acid polymerase. (1969) (50)
- cDNA encoding the glycosyl-phosphatidylinositol-specific phospholipase C of Trypanosoma brucei. (1988) (49)
- Kinetoplast maxicircle DNA replication in Crithidia fasciculata and Trypanosoma brucei (1995) (48)
- Heterogeneity of minicircles in kinetoplast DNA of Leishmania tarentolae. (1980) (48)
- Changes in network topology during the replication of kinetoplast DNA. (1995) (48)
- Multiple Triclosan Targets in Trypanosoma brucei (2004) (47)
- Unlocking the secrets of trypanosome kinetoplast DNA network replication. (2001) (47)
- A Mitochondrial DNA Primase from the Trypanosomatid Crithidia fasciculata * (1997) (46)
- Changes in Organization of Crithidia fasciculata Kinetoplast DNA Replication Proteins during the Cell Cycle (1998) (45)
- Overexpression of a Cytochrome b5 Reductase-like Protein Causes Kinetoplast DNA Loss in Trypanosoma brucei* (2006) (45)
- Gapped Minicircles. A novel replication intermediate of kinetoplast DNA. (1984) (43)
- Cleavage of trypanosome surface glycoproteins by alkaline trypsin-like enzyme(s) in the midgut of Glossina morsitans. (2003) (43)
- The initial step of in vitro synthesis of deoxyribonucleic acid by the T4 deoxyribonucleic acid polymerase. (1971) (42)
- Toxicity of myristic acid analogs toward African trypanosomes. (1994) (41)
- A mitochondrial heat shock protein from Crithidia fasciculata. (1993) (41)
- Effect of Hydroxyurea on Procyclic Trypanosoma brucei: an Unconventional Mechanism for Achieving Synchronous Growth (2007) (40)
- Inhibition of bloodstream form Trypanosoma brucei gene expression by RNA interference using the pZJM dual T7 vector. (2001) (40)
- A beta-like DNA polymerase from the mitochondrion of the trypanosomatid Crithidia fasciculata. (1994) (39)
- Immunobiology of nematode antigens. (1988) (38)
- Presence of a bent helix in fragments of kinetoplast DNA minicircles from several trypanosomatid species. (1984) (38)
- TbPIF1, a Trypanosoma brucei Mitochondrial DNA Helicase, Is Essential for Kinetoplast Minicircle Replication* (2009) (38)
- Closing the gaps in kinetoplast DNA network replication. (2004) (38)
- Myristate exchange on the Trypanosoma brucei variant surface glycoprotein. (1996) (38)
- Ribonucleotides associated with a gap in newly replicated kinetoplast DNA minicircles from Trypanosoma equiperdum. (1986) (38)
- Trypanosome metabolism of myristate, the fatty acid required for the variant surface glycoprotein membrane anchor. (1993) (38)
- Purification of a mitochondrial DNA polymerase from Crithidia fasciculata. (1992) (37)
- Synthesis and processing of kinetoplast DNA minicircles in Trypanosoma equiperdum (1989) (37)
- Myristate exchange. A second glycosyl phosphatidylinositol myristoylation reaction in African trypanosomes. (1994) (36)
- Purification and use of recombinant glycosylphosphatidylinositol-phospholipase C. (1995) (36)
- Defects in the N-Linked Oligosaccharide Biosynthetic Pathway in a Trypanosoma brucei Glycosylation Mutant (2004) (35)
- Genomic organization, chromosomal localization, and developmentally regulated expression of the glycosyl-phosphatidylinositol-specific phospholipase C of Trypanosoma brucei (1990) (35)
- The replication of kinetoplast DNA. (1980) (35)
- Microtechnique for electron microscopy of DNA. (1993) (30)
- The 3′-Terminal Nucleotide Sequences of Bacteriophage λ DNA (1973) (29)
- A knotted free minicircle in kinetoplast DNA. (1988) (29)
- Glycosyl phosphatidylinositol-specific phospholipase C of Trypanosoma brucei: expression in Escherichia coli. (1992) (28)
- Killing of Trypanosoma brucei by concanavalin A: structural basis of resistance in glycosylation mutants. (2000) (28)
- Identification and characterization of protozoan products that trigger the synthesis of IL-12 by inflammatory macrophages. (1997) (28)
- The fatty acids in unremodelled trypanosome glycosyl-phosphatidylinositols. (1994) (27)
- Rapid hydrolysis of deoxynucleoside triphosphates accompanies DNA synthesis by T4 DNA polymerase and T4 accessory proteins 44/62 and 45. (1982) (27)
- Depletion of Mitochondrial Acyl Carrier Protein in Bloodstream-Form Trypanosoma brucei Causes a Kinetoplast Segregation Defect (2011) (27)
- TbPIF5 Is a Trypanosoma brucei Mitochondrial DNA Helicase Involved in Processing of Minicircle Okazaki Fragments (2009) (27)
- The 3‐hydroxyacyl‐ACP dehydratase of mitochondrial fatty acid synthesis in Trypanosoma brucei (2008) (27)
- A glycolipid from Trypanosoma brucei related to the variant surface glycoprotein membrane anchor. (1989) (26)
- Protein glycosylation mutants of procyclic Trypanosoma brucei: defects in the asparagine-glycosylation pathway. (1999) (25)
- Replication of kinetoplast DNA in Trypanosoma equiperdum. Minicircle H strand fragments which map at specific locations. (1989) (25)
- Effects of RNA Interference of Trypanosoma brucei Structure-specific Endonuclease-I on Kinetoplast DNA Replication* (2005) (24)
- Detection of Glycophospholipid Anchors on Proteins (1993) (23)
- Isolation of kinetoplast DNA. (1999) (23)
- Virulence of Trypanosoma brucei strain 427 is not affected by the absence of glycosylphosphatidylinositol phospholipase C. (2001) (22)
- Inhibition of DNA replication in Escherichia coli by cyanide and carbon monoxide. (1975) (22)
- Structural and functional properties of Escherichia coli DNA polymerase. (1968) (22)
- Mitochondrial shape and function in trypanosomes requires the outer membrane protein, TbLOK1 (2013) (22)
- Lipid metabolism in Trypanosoma brucei: utilization of myristate and myristoyllysophosphatidylcholine for myristoylation of glycosyl phosphatidylinositols. (1996) (21)
- Silencing of genes required for glycosylphosphatidylinositol anchor biosynthesis in Burkitt lymphoma. (2009) (21)
- Glycosyl Phosphatidylinositol Myristoylation in African Trypanosomes (2000) (21)
- TbPIF8, a Trypanosoma brucei protein related to the yeast Pif1 helicase, is essential for cell viability and mitochondrial genome maintenance (2012) (20)
- Glycosyl phosphatidylinositol myristoylation in African trypanosomes. (1997) (20)
- Integration of pZJM library plasmids into unexpected locations in the Trypanosoma brucei genome. (2004) (19)
- Four Trypanosoma brucei fatty acyl-CoA synthetases: fatty acid specificity of the recombinant proteins. (2001) (18)
- Biosynthesis of glycosyl phosphatidylinositol protein anchors (1990) (18)
- Vaccination against parasites: special problems imposed by the adaptation of parasitic organisms to the host immune response. (1988) (18)
- TbKAP6, a Mitochondrial HMG Box-Containing Protein in Trypanosoma brucei, Is the First Trypanosomatid Kinetoplast-Associated Protein Essential for Kinetoplast DNA Replication and Maintenance (2014) (18)
- Control of schistosomiasis in man. (1988) (16)
- A nicked form of kinetoplast DNA in Leishmania tarentolae. (1977) (16)
- Plasmodium falciparum proteins at the host erythrocyte membrane: their biological and immunological significance and novel parasite organelles which deliver them to the cell surface. (1988) (16)
- The Mitochondrial DNA Polymerase β from Crithidia fasciculata Has 5′-Deoxyribose Phosphate (dRP) Lyase Activity but Is Deficient in the Release of dRP* (2002) (14)
- Toxoplasma gondii viewed from a virological perspective. (1988) (14)
- The biology of parasitism: a molecular and immunological approachcontinued. (1988) (13)
- Fatty acid remodeling of glycosyl phosphatidylinositol anchors in Trypanosoma brucei: incorporation of fatty acids other than myristate. (2001) (13)
- Symmetrical nucleotide sequences in the recognition sites for the ter function of bacteriophages P2, 299 and 186. (1977) (13)
- A Novel Glycosylphosphatidylinositol in African Trypanosomes (1999) (13)
- Trypanosome variant surface glycoprotein. (1988) (12)
- [3H]Myristate-Labeled Variant Surface Glycoprotein from Trypanosoma brucei: Preparation and Use in the Assay of Glycan-Phosphatidylinositol-Specific Lipases (1988) (11)
- RNAi libraries and kinetoplast DNA. (2005) (10)
- A refined localization of the mitochondrial DNA primase in Crithidia fasciculata. (1999) (10)
- Caenorhabditis elegans: a model for parasitic nematodes. (1988) (9)
- Assessing heterogeneity of the high-mannose glycopeptide gp432 on the variant surface glycoprotein of trypanosomes: a comparison of plasma desorption mass spectrometry and radiolabeling techniques. (1989) (9)
- Trypanocidal analogs of myristate and myristoyllysophosphatidylcholine. (1996) (8)
- An RNAi-Based Genomic Library for Forward Genetics in the African Trypanosome (2004) (8)
- Trypanosoma brucei: four tandemly linked genes for fatty acyl-CoA synthetases. (2000) (8)
- Network News: The Replication of (2012) (7)
- South American trypanosomiasis and leishmaniasis: endemic diseases of continental dimensions affecting poor, neglected, and underfunded people. (1988) (7)
- A density gradient fractionator. (1971) (6)
- Plasma membrane functions: a biochemical approach to understanding the biology of Leishmania. (1988) (6)
- A novel glycosyl phosphatidylinositol in african trypanosomcs: A possible catabolic intermediate (1996) (5)
- Glycosyl Phosphatidylinositol Myristoylation in African Trypanosomes NEW INTERMEDIATES IN THE PATHWAY FOR FATTY ACID REMODELING* (2000) (5)
- Developmental biology of Leishmania promastigotes. (1988) (5)
- Unsolved mysteries of trypanosome antigenic variation. (1988) (5)
- Molecular basis for interactions between parasites and the complement cascade. (1988) (5)
- Genetic control of immunity to parasite infection: studies of Trichinella-infected mice. (1988) (4)
- Purification and identification of a fatty acyl-CoA synthetase from Trypanosoma brucei. (2004) (4)
- Glycosyl phosphatidylinositol membrane anchors in African trypanosomes. (1991) (4)
- The 3'-terminal heptanucleotide sequence of the l strand of T7 deoxyribonucleic acid. (1973) (4)
- Antigens of Plasmodium falciparum and their potential as components of a malaria vaccine. (1988) (4)
- Immunity to murine malarial parasites. (1988) (4)
- The use of the T4 DNA polymerase in identification of 3' terminal nucleotide sequences of duplex DNA. (1974) (4)
- 40 Kinetoplast DNA Replication (1996) (4)
- Inhibition of DNA replication in Escherichia coli by dibromophenol and other uncouplers. (1977) (4)
- Induction of cell-mediated immunity as a strategy for vaccination against parasites. (1988) (3)
- A Passion for Parasites (2014) (3)
- A DNase from the trypanosomatid Crithidia fasciculata. (1995) (3)
- Glycolipid membrane anchor of the trypanosome variant surface glycoprotein: its biosynthesis and cleavage. (1988) (2)
- Glycosyl phosphatidylinositols in Trypanosoma brucei. (1993) (2)
- Detection of Glycophospholipid Anchors on Proteins (1993) (2)
- Biology of amebiasis: progress and perspectives. (1988) (2)
- The 3'-terminal nucleotide sequences of bacteriophage lambda DNA. (1973) (2)
- The Biosynthesis of GPI Anchors (2008) (1)
- Sporozoite malaria vaccines. (1988) (1)
- Incorporation of myristate into GPI by fatty acid remodeling in trypanosoma brucei (1998) (1)
- The biology of parasitism continued. (1988) (1)
- Inhibition of type II topoisomerase activity in the mitochondria of trypanosomes. (1990) (1)
- Silencing of Genes Required for Glycosylphosphatidylinositol Biosynthesis in a Burkitts’ Lymphoma Cell Line (Ramos) and Hematopoietic Stem Cells (HSC). (2006) (0)
- THE TRYPANOSOME SURFACE COAT AND THE TSETSE FLY: CUTTING A LONG STORY SHORT? (2000) (0)
- Table of Contents (1993) (0)
- DefectCauses a Kinetoplast Segregation Trypanosoma Protein in Bloodstream-Form Depletion of Mitochondrial Acyl Carrier (2011) (0)
- Nucleotide Sequencing of 3′ Termini of Duplex DNA with the T4 DNA Polymerase (1973) (0)
- KINETOPLAST DNA : THE REMARKABLE MITOCHONDRIAL DNA IN TRYPANOSOMES (1998) (0)
- Erratum: Inhibition of bloodstream form Trypanosoma brucei gene expression by RNA interference using the pZJM dual T7 vector (Molecular and Biochemical Parasitology (2001) 117 (111-113) (2002) (0)
- The 3 '-Terminal Nucleotide Sequences of Bacteriophage X DNA ( ter function / recognition site / rotational symmetry / coliphage ) (1999) (0)
- Inducible RNAi as a forward genetic tool in Trypanosoma brucei (2005) (0)
- Characterization of IL-12 and TNF-α inducing activities in toxoplasma gondil as protein-associated glycolipids (1996) (0)
- Identification of a variant surface glycoprotein (VSG) glycolipid precursor in Trypanosoma brucei (1986) (0)
- A DNase from the trypanosomatid Crfthidia fasciculata (2003) (0)
- Linearized free maxicircle DNA in Crithidia fasciculata is a product of topoisomerase II-mediated cleavage. (1996) (0)
- Purification of the trypanosome phospholipase C which cleaves the variant surface glycoprotein (1986) (0)
- The Relationship of RNA Synthesis, Nucleotide Pools, and Purine and Pyrimidine Transport in Tetrahymena (1983) (0)
- A gap in newly replicated kinetoplast DNA minicircles (1985) (0)
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