Paul Kleihues
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Published Works
- The 2007 WHO Classification of Tumours of the Central Nervous System (2007) (12134)
- The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary (2016) (11090)
- World Cancer Report (2003) (4217)
- World Health Organization classification of tumors (2000) (2745)
- The WHO Classification of Tumors of the Nervous System (2002) (1770)
- The New WHO Classification of Brain Tumours (1993) (1511)
- Genetic pathways to primary and secondary glioblastoma. (2007) (1457)
- Pathology and genetics of tumours of the nervous system. (2000) (1338)
- Population-based studies on incidence, survival rates, and genetic alterations in astrocytic and oligodendroglial gliomas. (2005) (1311)
- Epidemiology and etiology of gliomas (2005) (1179)
- IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas. (2009) (961)
- Genetic Pathways to Glioblastoma (2004) (919)
- The Definition of Primary and Secondary Glioblastoma (2012) (883)
- Histological Typing of Tumours of the Central Nervous System (1993) (805)
- IDH1 Mutations as Molecular Signature and Predictive Factor of Secondary Glioblastomas (2009) (650)
- Primary and secondary glioblastomas: from concept to clinical diagnosis. (1999) (634)
- Erratum: The 2007 WHO classification of tumours of the central nervous system (Acta Neuropathol (2007) vol. 114 (97-109)) (2007) (557)
- International Society of Neuropathology‐Haarlem Consensus Guidelines for Nervous System Tumor Classification and Grading (2014) (514)
- Overexpression of the EGF receptor and p53 mutations are mutually exclusive in the evolution of primary and secondary glioblastomas. (1996) (502)
- Li-Fraumeni and related syndromes: correlation between tumor type, family structure, and TP53 genotype. (2003) (474)
- Reversibility of ischemic brain damage. (1973) (467)
- Topographic anatomy and CT correlations in the untreated glioblastoma multiforme. (1988) (458)
- Tumors associated with p53 germline mutations: a synopsis of 91 families. (1997) (443)
- Genetic alterations and signaling pathways in the evolution of gliomas (2009) (428)
- Histopathology, classification, and grading of gliomas (1995) (350)
- Overexpression of the EGF Receptor and p53 Mutations are Mutually Exclusive in the Evolution of Primary and Secondary Glioblastomas (1996) (346)
- HIV‐Associated Disease of the Nervous System: Review of Nomenclature and Proposal for Neuropathology‐Based Terminology (1991) (335)
- Population-based study on incidence, survival rates, and genetic alterations of low-grade diffuse astrocytomas and oligodendrogliomas (2004) (326)
- The Use of the Monoclonal Antibody Ki-67 in the Identification of Proliferating Cells: Application to Surgical Neuropathology (1986) (324)
- p53 mutations are associated with 17p allelic loss in grade II and grade III astrocytoma. (1992) (320)
- Central Neurocytoma: A Synopsis of Clinical and Histological Features (1993) (297)
- APC mutations in sporadic medulloblastomas. (2000) (273)
- PTEN (MMAC1) Mutations Are Frequent in Primary Glioblastomas (de novo) but not in Secondary Glioblastomas (1998) (271)
- Incidence and timing of p53 mutations during astrocytoma progression in patients with multiple biopsies. (1997) (265)
- Correlation of clinical and pathological features in surgically treated craniopharyngiomas. (1990) (261)
- Promoter methylation of the DNA repair gene MGMT in astrocytomas is frequently associated with G:C --> A:T mutations of the TP53 tumor suppressor gene. (2001) (254)
- p14ARF Deletion and Methylation in Genetic Pathways to Glioblastomas (2001) (253)
- A population-based study of the incidence and survival rates in patients with pilocytic astrocytoma. (2003) (241)
- Resuscitation of the monkey brain after one hour complete ischemia. III. Indications of metabolic recovery (1975) (234)
- Soluble decoy receptor 3 is expressed by malignant gliomas and suppresses CD95 ligand-induced apoptosis and chemotaxis. (2001) (232)
- Mutations of the p53 tumor suppressor gene in neoplasms of the human nervous system (1993) (226)
- Genetic profile of gliosarcomas. (2000) (225)
- THE EFFECT OF ISCHAEMIA AND RECIRCULATION ON PROTEIN SYNTHESIS IN THE RAT BRAIN (1977) (219)
- TERT promoter mutations in primary and secondary glioblastomas (2013) (212)
- The p53 gene and its role in human brain tumors (1995) (212)
- p53 mutations in nonastrocytic human brain tumors. (1991) (211)
- Atypical Central Neurocytoma (1997) (202)
- PATHOLOGY OF EXPERIMENTAL NEUROGENIC TUMORS CHEMICALLY INDUCED DURING PRENATAL AND POSTNATAL LIFE (1969) (196)
- Promoter Hypermethylation of the RB1 Gene in Glioblastomas (2001) (190)
- Chemical carcinogenesis in the nervous system. Preferential accumulation of O6-methylguanine in rat brain deoxyribonucleic acid during repetitive administration of N-methyl-N-nitrosourea. (1975) (190)
- Gene expression profiling of low-grade diffuse astrocytomas by cDNA arrays. (2000) (189)
- Protein synthesis in the cat brain after prolonged cerebral ischemia. (1971) (189)
- Amplification and Overexpression of MDM2 in Primary (de novo) Glioblastomas (1997) (185)
- PURINE NUCLEOTIDE METABOLISM IN THE CAT BRAIN AFTER ONE HOUR OF COMPLETE ISCHEMIA (1974) (182)
- Carcinogenicity of N-methyl-N-nitrosourea: possible role of excision repair of O6-methylguanine from DNA. (1974) (178)
- Loss of Heterozygosity on Chromosome 10 Is More Extensive in Primary (De Novo) Than in Secondary Glioblastomas (2000) (177)
- Alterations of cell cycle regulatory genes in primary (de novo) and secondary glioblastomas (1997) (175)
- Molecular classification of low-grade diffuse gliomas. (2010) (173)
- Chemical carcinogenesis in the nervous system. (1976) (164)
- Histological Classification of Tumours of the Central Nervous System (1993) (159)
- Genetic profile of astrocytic and oligodendroglial gliomas (2011) (157)
- Identical Mutations of the p53 Tumor Suppressor Gene in the Gliomatous and the Sarcomatous Components of Gliosarcomas Suggest a Common Origin from Glial Cells (1995) (152)
- Growth rate of human pituitary adenomas. (1987) (151)
- Null mutation of DNA strand break-binding molecule poly(ADP-ribose) polymerase causes medulloblastomas in p53(-/-) mice. (2003) (151)
- Fas Ligand Expression in Glioblastoma Cell Lines and Primary Astrocytic Brain Tumors (1997) (149)
- AXIN1 mutations but not deletions in cerebellar medulloblastomas (2003) (146)
- p53 Mutations in sporadic adrenocortical tumors (1993) (144)
- Predominant Expression of Mutant EGFR (EGFRvIII) is Rare in Primary Glioblastomas (2004) (141)
- Histogenesis and differentiation potential of central neurocytomas. (1991) (141)
- O6-alkylguanine-DNA alkyltransferase and sensitivity to procarbazine in human brain-tumor xenografts. (1989) (137)
- PTEN methylation and expression in glioblastomas (2003) (137)
- Loss of Heterozygosity on Chromosome 19 in Secondary Glioblastomas (2000) (136)
- Cytologic composition of the untreated glioblastoma with implications for evaluation of needle biopsies (1989) (135)
- Phenotype versus genotype correlation in oligodendrogliomas and low-grade diffuse astrocytomas (2002) (133)
- Molecular pathogenesis of astrocytic tumours (2004) (132)
- O6-alkylguanine-DNA alkyltransferase activity in human brain and brain tumors. (1984) (132)
- Acquisition of the glioblastoma phenotype during astrocytoma progression is associated with loss of heterozygosity on 10q25-qter. (1999) (124)
- Identification in Human Brain Tumors of DNA Sequences Specific for SV40 Large T Antigen (1999) (117)
- Persistent inhibition of protein synthesis precedes delayed neuronal death in postischemic gerbil hippocampus (2004) (115)
- Prosopagnosia and agnosia for noncanonical views. An autopsied case. (1988) (115)
- Absence of p53 gene mutations in cutaneous melanoma. (1994) (113)
- Exhaustion and recovery of repair excision of O6-methylguanine from rat liver DNA (1976) (112)
- The 2007 WHO ClassiWcation of Tumours of the Central Nervous System (2007) (111)
- Phenotype vs Genotype in the Evolution of Astrocytic Brain Tumors (2000) (111)
- Patterns of differentiation in central neurocytoma. An immunohistochemical study of eleven biopsies. (1990) (110)
- Age as a Predictive Factor in Glioblastomas: Population-Based Study (2009) (110)
- Concurrent Inactivation of RB1 and TP53 Pathways in Anaplastic Oligodendrogliomas (2001) (109)
- Role of gemistocytes in astrocytoma progression. (1997) (104)
- 1,2-Dimethylhydrazine-induced methylation of DNA bases in various rat organs and the effect of pretreatment with disulfiram. (1979) (100)
- Determination of p53 mutations, EGFR overexpression, and loss of p16 expression in pediatric glioblastomas. (1997) (99)
- Expression of Fas/APO-1 during the progression of astrocytomas. (1995) (99)
- Neuropathology of the acquired immune deficiency syndrome (AIDS): a report of 135 consecutive autopsy cases from Switzerland (2004) (95)
- p53 and PTEN gene mutations in gemistocytic astrocytomas (1998) (91)
- Preradiation chemotherapy of children and young adults with malignant brain tumors: results of the German pilot trial HIT'88/'89. (1998) (91)
- Primitive neuroectodermal tumors after prophylactic central nervous system irradiation in children. Association with an activated K‐ras gene (1992) (90)
- Promoter hypermethylation and homozygous deletion of the p14ARF and p16INK4a genes in oligodendrogliomas (2001) (88)
- CD95 Ligand: Lethal Weapon Against Malignant Glioma? (1998) (88)
- Genetic alterations associated with the evolution and progression of astrocytic brain tumours (2004) (84)
- Lipomatous medulloblastoma in adults. A distinct clinicopathological entity. (1996) (82)
- Prognostic impact of TP53 mutations and P53 protein overexpression in supratentorial WHO grade II astrocytomas and oligoastrocytomas. (2002) (82)
- The Science and Practice of Carcinogen Identification and Evaluation (2004) (81)
- Necrogenesis and Fas/APO-1 (CD95) Expression in Primary (de novo) and Secondary Glioblastomas (1998) (81)
- Selective acquisition of IDH1 R132C mutations in astrocytomas associated with Li-Fraumeni syndrome (2009) (80)
- Stratification of medulloblastoma on the basis of histopathological grading (2006) (80)
- Genetics of Glioma Progression and the Definition of Primary and Secondary Glioblastoma (1997) (79)
- Preferential methylation of target organ DNA by the oesophageal carcinogen N-nitrosomethylbenzylamine. (1980) (77)
- In vivo metabolism and reaction with DNA of the cytostatic agent, 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide (DTIC). (1986) (77)
- Loss of DCC expression and glioma progression. (1997) (75)
- Genetic profile of the giant cell glioblastoma. (1999) (74)
- Patterns of differentiation in central neurocytoma (1990) (73)
- Intratumoral Patterns of Genomic Imbalance in Glioblastomas (2010) (73)
- p53 protein accumulation and gene mutations in human glioma cell lines (1993) (73)
- Principles of Chemoprevention (1996) (71)
- Selective mutation of codons 204 and 213 of the p53 gene in rat tumors induced by alkylating N-nitroso compounds. (1992) (70)
- Infrequent alterations of the p15, p16, CDK4 and CYCLIN D1 genes in non‐astrocytic human brain tumors (1996) (68)
- Long-term persistence of O6-methylguanine in rat brain DNA (1977) (68)
- Human astrocytic brain tumors express APO2L/TRAIL (1999) (66)
- Preferential expression of Fas/APO1 (CD95) and apoptotic cell death in perinecrotic cells of glioblastoma multiforme (1996) (66)
- Differentiation in the medulloblastoma. A histological and immunohistochemical study. (1987) (65)
- Reduced expression of the Aα subunit of protein phosphatase 2A in human gliomas in the absence of mutations in the Aα and Aβ subunit genes (2001) (62)
- Genetic and Expression Profiles of Cerebellar Liponeurocytomas (2004) (61)
- Morphologic evaluation of stereotactic brain tumour biopsies. (1984) (60)
- p53 Mutations versus EGF Receptor Expression in Giant Cell Glioblastomas (1997) (60)
- p53 gene mutations in oropharyngeal carcinomas: A comparison of solitary and multiple primary tumours and lymph‐node metastases (1994) (58)
- ALKYLATION OF RAT BRAIN NUCLEIC ACIDS BY N‐METHYL‐N‐NITROSOUREA AND METHYL METHANESULPHONATE (1973) (58)
- Simultaneous clinical manifestation of subependymoma of the fourth ventricle in identical twins. Case report. (1979) (58)
- Astrocytomas and Choroid Plexus Tumors in Two Families with Identical p53 Germline Mutations (1998) (57)
- p53 mutations in primary human lung tumors and their metastases (1994) (57)
- Hemizygous or homozygous deletion of the chromosomal region containing the p16INK4a gene is associated with amplification of the EGF receptor gene in glioblastomas (1997) (56)
- Hans‐Joachim Scherer (1906‐1945), Pioneer in Glioma Research (1999) (56)
- Genetic Alterations in Gliosarcoma and Giant Cell Glioblastoma (2016) (55)
- Gene expression profiling and subgroup identification of oligodendrogliomas (2004) (54)
- Clinical growth rate of acoustic schwannomas: correlation with the growth fraction as defined by the monoclonal antibody ki-67. (1991) (53)
- The changing pattern of human immunodeficiency virus-associated cerebral toxoplasmosis: a study of 46 postmortem cases (2004) (51)
- Morphological markers in neuro-oncology. (1987) (51)
- Sequential morphological changes in the dog brain after interstitial iodine- 125 irradiation. (1983) (50)
- Genetic profiling of CNS tumors extends histological classification (2010) (50)
- Methylation of the p73 gene in gliomas (2002) (49)
- DNA alkylation in mice with genetically different susceptibility to 1,2-dimethylhydrazine-induced colon carcinogenesis. (1978) (49)
- Cell type-specific tumor induction in neural transplants by retrovirus-mediated oncogene transfer. (1991) (48)
- Regionally Selective Inhibition of Cerebral Protein Synthesis in the Rat During Hypoglycemia and Recovery (1984) (48)
- Cerebellar Liponeurocytoma with an Unusually Aggressive Clinical Course: Case Report (2003) (46)
- Progressive diffuse leukoencephalopathy in patients with acquired immune deficiency syndrome (AIDS) (2004) (46)
- Familial Brain Tumour Syndrome Associated with a p53 Germline Deletion of Codon 236 (1995) (44)
- Differential proliferative response of gastric mucosa during carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in susceptible ACI rats, resistant Buffalo rats, and their hybrid F1 cross. (1988) (41)
- Excision of O6-methylguanine from DNA of various mouse tissues following a single injection of N-methyl-Nitrosourea. (1977) (41)
- Modulation of N-nitrosomethylbenzylamine bioactivation by diallyl sulfide in vivo. (1992) (40)
- Amyloid deposits in pituitary adenomas. Differentiation of two types. (1987) (39)
- Reduced expression of the Aalpha subunit of protein phosphatase 2A in human gliomas in the absence of mutations in the Aalpha and Abeta subunit genes. (2001) (39)
- A model for primitive neuroectodermal tumors in transgenic neural transplants harboring the SV40 large T antigen. (1994) (38)
- Chemical neuro-oncogenesis: role of structural DNA modifications, DNA repair and neural target cell population. (1984) (38)
- Why can't we convince the young not to smoke? (1999) (37)
- Interaction of the carcinogen 3,3-dimethyl-1-phenyltriazene with nucleic acids of various rat tissues and the effect of a protein-free diet. (1976) (37)
- PCR identification of HIV‐1 DNA sequences in brain tissue of patients with AIDS encephalopathy (1993) (37)
- DNA methylation in rat tissues by a series of homologous aliphatic nitrosamines ranging from N-nitrosodimethylamine to N-nitrosomethyldodecylamine. (1987) (37)
- Inhibition of the hepatic O6-alkylguanine-DNA alkyltransferase in vivo by pretreatment with antineoplastic agents. (1989) (36)
- Germline SDHD mutation in paraganglioma of the spinal cord (2001) (36)
- APO2L/TRAIL expression in human brain tumors (2000) (35)
- The monoclonal antibody Ki-67 as a marker for proliferating cells in stereotactic biopsies of brain tumours (2005) (35)
- Expression of variant CD44 epitopes in human astrocytic brain tumors (1995) (35)
- A case history of glioma progression (1999) (35)
- Pregnancy, immunosupression and reactivation of latent toxoplasmosis (1995) (35)
- Retrovirus‐Mediated Oncogene Transfer into Neural Transplants (1991) (34)
- Time course and spatial distribution of neodymium: yttrium-aluminum-garnet (Nd:YAG) laser-induced lesions in the rat brain. (1985) (34)
- Endogenous deoxyribonucleic Acid (DNA) damage in human tissues: a comparison of ethenobases with aldehydic DNA lesions. (2003) (33)
- Formation and persistence of O6-(2-hydroxyethyl)-2' -deoxyguanosine in DNA of various rat tissues following a single dose of N-nitroso-N-(2-hydroxyethyl)urea. An immuno-slot-blot study. (1988) (33)
- An international evaluation of the cancer-preventive potential of nonsteroidal anti-inflammatory drugs. (1997) (32)
- Oncogene complementation in fetal brain transplants. (1992) (32)
- More about: cell and molecular biology of simian virus 40: implications for human infections and disease. (2000) (32)
- [Distribution of N-( 14 C) methyl-N-nitrosourea in the rat after its systemic administration]. (1971) (32)
- Correlation of DNA methylation by methyl(acetoxymethyl)nitrosamine with organ-specific carcinogenicity in rats. (1979) (32)
- Cerebral Protein Synthesis during Long-Term Recovery from Severe Hypoglycemia (1986) (32)
- Definitions and Explanatory Notes (1993) (32)
- Carcinomas of the renal pelvis associated with smoking and phenacetin abuse: p53 mutations and polymorphism of carcinogen‐metabolising enzymes (1998) (31)
- Differentiation in the medulloblastoma (2004) (31)
- Experimental Data on Early and Late Morphologic Effects of Permanently Implanted Gamma and Beta Sources (Iridium-192, Iodine-125 and Yttrium-90) in the Brain (1984) (31)
- Prevention and early detection (1996) (31)
- Smoking cessation in cancer prevention. (2001) (31)
- Morphology of Intracranial Tumours and Adjacent Brain Structures Following Interstitial Iodine-125 Radiotherapy (1984) (31)
- Persistence of alkylated DNA bases in the Mongolian gerbil (Meriones unguiculatus) following a single dose of methylnitrosourea +. (1980) (31)
- Genetic evidence of the neoplastic nature of gemistocytes in astrocytomas (2001) (30)
- Location of N-methyl-N'-nitro-N-nitrosoguanidine-induced gastrointestinal tumors correlates with thiol distribution. (1983) (30)
- Definition of Primary and Secondary Glioblastoma—Response (2014) (30)
- The 2007 WHO classification of tumours of the central nervous system (2007) (30)
- Iodine-125 interstitial irradiation of virally induced dog brain tumours. (1984) (30)
- Computed tomography in Hallervorden-Spatz disease. (1987) (29)
- p53 mutations in phenacetin-associated human urothelial carcinomas. (1993) (29)
- Regional impairment of protein synthesis in the rat brain during bicuculline-induced seizures (1984) (28)
- Effects of ethanol and various alcoholic beverages on the formation of O6-methyldeoxyguanosine from concurrently administered N-nitrosomethylbenzylamine in rats: a dose-response study. (1992) (28)
- Ki-67 immunoperoxidase stain as marker for the histological grading of nervous system tumours. (1988) (25)
- The Recurrent Artery of Heubner (1971) (24)
- Angiogenic activity of the K-fgf/hst oncogene in neural transplants. (1992) (24)
- DNA methylation by dimethylnitrosamine in the Mongolian gerbil (Meriones unguiculatus): indications of a deficient, noninducible hepatic repair system for O6-methylguanine. (1983) (24)
- Genetic and environmental factors in the etiology of human brain tumors. (1995) (23)
- Tumours of the peripheral and central nervous system induced in BD-rats by prenatal application of methyl methanesulfonate. (1972) (23)
- Regional Heterogeneity of L-[3-3H]Tyrosine Incorporation into Rat Brain Proteins during Severe Hypoglycemia (1982) (22)
- Mechanism of esophageal tumor induction in rats by N-nitrosomethylbenzylamine and its ring-methylated analog N-nitrosomethyl(4-methylbenzyl)amine. (1982) (22)
- DNA repair as regulatory factor in the organotropy of alkylating carcinogens. (1979) (22)
- Reaction of 7,12‐dimethylbenz(a)anthracene with DNA of fetal and maternal rat tissues in vivo (1978) (21)
- Organ and cell specificity of DNA methylation by N-nitrosomethylamylamine in rats. (1988) (20)
- Prevalence of human papilloma virus DNA in head and neck cancers carrying wild-type or mutant p53 tumor suppressor genes. (1999) (20)
- Type and frequency of p53 mutations in tumors of the nervous system and its coverings. (1994) (20)
- Selective induction by N-nitrosoethylurea of oligodendrogliomas in fetal forebrain transplants. (1988) (20)
- Reaction of N‐methyl‐N‐nitrosourea with DNA of neuronal and glial cells in vivo (1973) (20)
- Morphology of malignant gliomas induced in rabbits by systemic application of N-Methyl-N-nitrosourea (2004) (20)
- Methylation versus ethylation of DNA in target and nontarget tissues of Fischer 344 rats treated with N-nitrosomethylethylamine. (1986) (20)
- Mutation analysis of hBUB1, hBUBR1 and hBUB3 genes in glioblastomas (2001) (19)
- Invasiveness in vitro and biological markers in human primary glioblastomas (2001) (19)
- Tumor induction by ras and myc oncogenes in fetal and neonatal brain: modulating effects of developmental stage and retroviral dose (2004) (19)
- Reduced expression of the P2 form of the gap junction protein connexin43 in malignant meningiomas. (1997) (19)
- Role of Biomarkers in the Clinical Management of Glioblastomas: What are the Barriers and How Can We Overcome Them? (2013) (19)
- [The infarct of the posterior cerebral artery: pathogenesis and topographical relationship to the visual cortex]. (1966) (18)
- Repair excision of alkylated bases from DNA in vivo. (1976) (18)
- Second Primary Glioblastoma (2001) (18)
- Ki‐ras mutations in spontaneous and chemically induced renal tumors of the rat (1991) (18)
- Inhibition of protein synthesis by N-methyl-N-nitrosourea in vivo. (1973) (17)
- TP53, MSH4, and LATS1 germline mutations in a family with clustering of nervous system tumors. (2014) (17)
- Distribution and immunoreactivity of cerebral micro-hamartomas in bilateral acoustic neurofibromatosis (neurofibromatosis 2) (2004) (17)
- Germline rearrangements in families with strong family history of glioma and malignant melanoma, colon, and breast cancer (2014) (17)
- Mutation analysis of hBUB1, hBUBR1 and hBUB3 genes in glioblastomas (2001) (17)
- DNA modification and repair in vivo: towards a biochemical basis of organ-specific carcinogenesis by methylating agents. (1983) (17)
- Oskar and Cécile Vogt, Lenin's Brain and the Bumble‐Bees of the Black Forest (1992) (17)
- Transparency at the International Agency for Research on Cancer (IARC) (2003) (17)
- HIV Encephalopathy: Incidence, Definition and Pathogenesis (1991) (16)
- Selective induction of melanomas in gerbils (Meriones unguiculatus) following postnatal administration of N-ethyl-N-nitrosourea. (1978) (16)
- Experimental gastric cancer. (1991) (16)
- Cerebellar medullomyoblastoma with advanced neuronal differentiation and hamartomatous component (2004) (16)
- DNA methylation by N-nitrosomethylbenzylamine in target and non-target tissues of NMRI mice. (1981) (16)
- Neuropathology and pathogenesis of HIV encephalopathies. (1992) (15)
- Reaction of benzo(a)pyrene and 7,12-dimethylbenz(a)anthracene with DNA of various rat tissues in vivo. (1980) (15)
- DNA alkylation and neuro-oncogenesis by 3,3-dimethyl-1-phenyltriazene (1978) (15)
- Molecular analysis of glioma and skin‐tumour alterations in a xeroderma‐pigmentosum child (1999) (15)
- DNA methylation in maternal, fetal and neonatal rat tissues following perinatal administration of procarbazine (2004) (14)
- Pulmonary edema during bicuculline-induced seizures in rats (1981) (14)
- Cellular and Molecular Aspects of Neurocarcinogenesis (1990) (14)
- A new approach to the molecular basis of neoplastic transformation in the brain (1992) (13)
- Electron Microscopic Observations on Different Models of Acute Experimental Brain Edema (1967) (13)
- Extent of DNA 2-hydroxyethylation by N-nitrosomethylethylamine and N-nitrosodiethylamine in vivo. (1986) (13)
- Kernicterus in an adult (1986) (13)
- Etiology of cancer in humans and animals. (1996) (13)
- Genetic alterations associated with glioma progression. (1994) (13)
- Wernicke's encephalopathy with ballooned neurons in the mamillary bodies: an immunohistochemical study (1997) (12)
- Brain Tumors in S100&bgr;-v-erbB Transgenic Rats (2006) (12)
- Tissue polypeptide antigen staining of the chordoma and notochordal remnants (2004) (12)
- Akinetic mutism in bilateral necrotizing leucoencephalopathy after radiation and chemotherapy: Electrophysiological and autopsy findings (1992) (12)
- Mechanism of perinatal tumor induction by neuro-oncogenic alkylnitrosoureas and dialkylaryltriazenes. (1979) (11)
- Dimethylnitrosamine-induced inhibition of hepatic protein synthesis in vitro and the effect of pretreatment with cystamine or pregnenolone-16alpha-carbonitrile. (1975) (11)
- Surgical Pathology of the Nervous System and Its Coverings. Fourth Edition (2003) (11)
- DNA methylation in rat stomach and duodenum following chronic exposure to N-methyl-N'-nitro-N-nitrosoguanidine and the effect of dietary taurocholate. (1988) (10)
- Intracerebral venous thrombosis and hematoma secondary to high-voltage brain injury. (1997) (10)
- Brain tumors in S100beta-v-erbB transgenic rats. (2006) (10)
- Diagnostic Potential of Stereotactic Biopsy of Brain Tumours. A Report of 400 Cases (1982) (9)
- [Origin of colloid cyst: immunoperoxidase study]. (1987) (9)
- Delayed inhibition of protein synthesis during recirculation after compression ischemia of the rat brain. (1977) (9)
- Regional protein synthesis in the rat brain during bicuculline-induced epileptic seizures (2004) (9)
- K-ras mutations are frequent in pulmonary squamous cell carcinomas but not in adenocarcinomas of WBN/Kob rats induced by N-nitrosobis(2-oxopropyl)amine. (1993) (9)
- Marchiafava-bignami disease (1988) (9)
- Early and late effects on the normal dog brain of permanent interstitial iridium-192 irradiation (2004) (9)
- Immunohistochemical Assessments of P53 Protein Accumulation and Tumor Growth Fraction During the Progression of Astrocytomas (1996) (8)
- Complementary tumor induction in neural grafts exposed to N-ethyl-N-nitrosourea and an activated myc gene. (1993) (8)
- A Correlative Computed Tomography and Morphological Study (1988) (8)
- Bioactivation of asymmetric N-dialkylnitrosamines in rat tissues derived from the ventral entoderm. (1991) (8)
- Connatal polyneuropathy — A case with proliferated microfilaments in schwann cells (2004) (8)
- DNA MODIFICATION AND REPAIR IN THE EXPERIMENTAL INDUCTION OF NERVOUS SYSTEM TUMORS BY CHEMICAL CARCINOGENS * (1982) (8)
- Braf Mutations Initiate the Development of Rat Gliomas Induced by Postnatal Exposure to N-Ethyl-N-Nitrosourea. (2016) (8)
- Resistance to hypoglycemia of cerebellar transplants in the rat forebrain (2004) (7)
- P XII.6 Comparison of inherited and somatic p53 mutations in human cancers (1997) (7)
- Subsets of Glioblastoma: Clinical and Histological vs. Genetic Typing. (1998) (7)
- Oncogene transfer into the brain. (1994) (7)
- Primitive neuroectodermal tumor with choroid plexus differentiation. (1985) (7)
- Reaction of N-n-butyl-N-nitrosourea with DNA in vitro. (1980) (7)
- neu mutations and loss of normal allele in schwannomas induced by N-ethyl-N-nitrosourea in rats. (1993) (7)
- Nutrition and cancer: a complex relationship. (2002) (7)
- HIV encephalopathy: incidence, definition and pathogenesis. Results of a Swiss collaborative study. (1991) (7)
- Interorgan shift of nitrosamine metabolism by dietary ethanol. (1987) (7)
- Neuropathology of central nervous system human immunodeficiency virus infection (1994) (7)
- Regional incorporation of L-[3-3H]tyrosine into cat brain proteins after 1 hour of complete ischemia (2004) (6)
- Alterations of the RRAS and ERCC1 Genes at 19q13 in Gemistocytic Astrocytomas (2014) (6)
- DNA methylation in the digestive tract of F344 rats during chronic exposure toN-methyl-N-nitrosourea (2005) (6)
- DNA methylation in various rat tissues by the esophageal carcinogen N-nitrosomethyl-n-amylamine and six of its positional isomers. (1991) (5)
- [Cell kinetics of human meningiomas and neurinomas--Ki-67 PAP stain]. (1988) (5)
- Immunohistochemical Assessment of Differentiation and DNA Replication in Human Brain Tumors (1989) (5)
- Definition and incidence of AIDS-associated CNS lesions. (1990) (5)
- [The tumor suppressor gene p53 and its significance for dermatology]. (1994) (5)
- Organ specificity, metabolism and reaction with DNA of aliphatic nitrosomethylalkylamines. (1987) (5)
- Tumour induction in fetal brain transplants exposed to the viral oncogenes polyoma middle T and v-src. (1989) (5)
- Erratum: Mutation analysis of hBUB1, hBUBR1 and hBUB3 genes in glioblastomas (Acta Neuropathologica (2001) vol. 101 (297-304)) (2001) (4)
- Bioactivation of N-nitrosomethylbenzylamine and N-nitrosomethyl-amylamine in oesophageal papillomas. (1990) (4)
- Methylation of the p 73 gene in gliomas (4)
- Direct DNA sequencing following SSCP analysis. (1994) (4)
- Intracranial mixed germ cell tumor with syncytiotrophoblastic giant cells and precocious puberty (2004) (3)
- N-methyl-N-nitrosourea induced changes in the labeling by [14C]orotate of RNA and acid-soluble fractions in rat kidney and liver (1972) (3)
- Distribution of human immunodeficiency virus (HIV) in the CNS of children with severe HIV encephalomyelopathy (2004) (3)
- Selective Induction by TV-Nitrosoethylureaof Oligodendrogliomasin Fetal Forebrain Transplants1 (1988) (3)
- IARC Working Group on Carcinogenicity of Beryllium. (1994) (3)
- Single-dose toxicokinetics ofN-nitrosomethylethylamine andN-nitrosomethyl (2,2,2-trideuterioethyl)amine in the rat (2005) (3)
- Recovery of cerebral energy metabolism after complete ischemia of one hour's duration (2004) (3)
- Toward methylation-based classification of central nervous system tumors. (2018) (3)
- [Cell kinetics of oligodendroglioma and oligo-astrocytoma--Ki-67 PaP study]. (1988) (3)
- Chairman’s Commentary (1987) (3)
- Reply to Marc Scherer (2013) (3)
- Beta-deuteration of N-nitrosoethylmethylamine causes a shift in DNA methylation from rat liver to esophagus. (1991) (3)
- Advances in Brief p 53 Mutations in Nonastrocytic Human Brain Tumors ' (2006) (3)
- p53 mutations in oropharyngeal carcinomas: a comparison of solitary and multiple primary tumours and lymph node metastases. (1994) (3)
- DNA hydroxyethylation by hydroxyethylnitrosoureas in relation to their organ specific carcinogenicity in rats. (1991) (3)
- Nafenopin-induced rat liver peroxisome proliferation reduces DNA methylation by N-nitrosodimethylamine in vivo. (1985) (3)
- Comparative studies on hepatic DNA alkylation in rats by N-nitrosomethylethylamine and N-nitrosodimethylamine plus N-nitrosodiethylamine (2004) (3)
- Reaction of methyl methanesulphonate with nucleic acids of fetal and newborn rats in vivo (2004) (3)
- The Development of Neuropathology at the Massachusetts General Hospital and Harvard Medical School (1994) (3)
- The future of population monitoring in cancer research. (1996) (3)
- Metabolism of N-nitrosomethylbenzylamine in the mongolian gerbil (meriones unguiculatus). (1982) (3)
- Germline MSH6 Mutation in a Patient With Two Independent Primary Glioblastomas (2017) (3)
- Effect of pretreatment with pregnenolone-16 alpha-carbonitrile and protein-free diet on the metabolism and carcinogenicity of dimethylnitrosamine. (1981) (3)
- Hermann Druckrey. (1994) (2)
- [Induction of primitive neuroectodermal tumors by oncogene complementation]. (1990) (2)
- [p53 mutation in phenacetin-induced urothelial carcinomas]. (1993) (2)
- Integrity of the Conduct of the IARC Monographs Program (2003) (2)
- [Normal and pathological anatomy of the midbrain]. (1968) (2)
- Greenfield's Neuropathology Fifth Edition, Edited by J.H. Adams and L.W. Duchen (1992) (2)
- Postischemic Recovery of Nucleotide Metabolism in the Cat Brain (1975) (2)
- Developmental Neuro-Oncogenesis in Experimental Animals (1982) (2)
- TOPOGRAPHIC ANATOMY AND CYTOLOGIC COMPOSITION OF THE UNTREATED GLIOBLASTOMA MULTIFORME (1986) (2)
- [Differentiation of medulloblastoma: immunohistochemistry of 247 cases from the therapy trial SIOP/GPO MED 84]. (1988) (2)
- Mutagenicity, DNA damage and DNA adduct formation by N-nitroso-2-hydroxyalkylamine and corresponding aldehydes. (1991) (2)
- Classification of tumors of the nervous system: an historical annotation (2006) (2)
- Occurrence of breast cancer: Facts and trends (1996) (2)
- [The identification of proliferating cells in nervous system neoplasms by use of the monoclonal antibody Ki-67]. (1987) (2)
- DNA Alkylationin Mice with GeneticallyDifferentSusceptibilityto 1,2-Dimethylhydrazine-induced Colon Carcinogenesis1 (1978) (2)
- From host factors to genetic susceptibility. (1996) (1)
- DNA methylation by N-nitrosomethylbenzylamine in target and non-target tissues of laboratory rodents. Comparison with carcinogenicity. (1984) (1)
- [On bilateral symmetrical infarct of the occipital lobe. Pathology and clinico-ophthalmological findings]. (1966) (1)
- Polymorphic Genotype Matching in Acquired Creutzfeldt-Jakob Disease: An Analysis of Donor/Recipient Case Pairs (1998) (1)
- [Nervous system pathology in AIDS: results of a collaborative autopsy study from Switzerland]. (1990) (1)
- ROLE OF GEMISTOCYTIC ASTROCYTES IN GLIOMA PROGRESSION (1996) (1)
- Metabolism of N-nitrosodimethylamine and N-nitrosomethylbenzylamine in domestic fowls: DNA alkylation and potential target sites for carcinogenicity. (1986) (1)
- Involvement of thiols in gastric cancer induced by N-methyl-N'-nitro-N-nitrosoguanidine: biochemical and autoradiographic studies. (1984) (1)
- [HIV-associated encephalopathy]. (1986) (1)
- Meeting Report An International Evaluation of the Cancer-Preventive Potential of Nonsteroidal Anti-inflammatory Drugs 1 (1997) (1)
- Repair of O6-alkylguanine in cellular DNA: significance for tumour induction and chemotherapy (1984) (1)
- Cell-specific brain tumour induction in neural transplants: evidence for multistep carcinogenesis in the nervous system. (1989) (1)
- [Incorporation of L-3H-tyrosine by neuroglia in experimental brain edema]. (1967) (1)
- N-methyl-N-nitrosourea induced changes in the labeling by ( 14 C)orotate of RNA and acid-soluble fractions in rat kidney and liver. (1972) (1)
- Genetic Tumor Epidemiology: Identifying Causative Carcinogenic Agents and Their Transforming Mutations (1994) (1)
- [Blockage of DNA synthesis by N-methyl-N-nitrososurea in vivo]. (1969) (1)
- [Current problems in the area of the pathogenesis, clinical picture and therapy of cerebrovascular disorders]. (1966) (1)
- [Recovery after complete cerebral ischemia: free amino acid levels in the brain tissue during and after complete cerebral ischemia (author's transl)]. (1978) (1)
- [Proceedings: Recirculation following cerebral ischemia lasting one hour]. (1974) (1)
- IARC WORKING GROUP ON CARCINOGENICITY OF BERYLLIUM. AUTHOR'S REPLY (1994) (1)
- Periodic depression by N-methyl-N-nitrosourea of electrocortical activity in the cat brain (1971) (1)
- Genetic basis of glioma progression (2003) (1)
- Persistence of alkylated sites in DNA and its biological significance. (1983) (1)
- [The clinical aspects of carotid stenoses and the scope of medical treatment]. (1966) (1)
- [Biochemical study of the position specificity of rat gastrointestinal cancer induced by MNNG]. (1984) (1)
- The Art of Brain Tumour Classification ‐A Tribute to Lucien J. Rubinstein (1925–1990) (1990) (1)
- [Morphology and growth of tumors of the nervous system produced transplacentally by ethylnitroso-urea]. (1968) (1)
- Metabolism of n nitrosomethylethylamine in vivo results in 2 hydroxyethylation of dna (1986) (0)
- [Action mechanism of the carcinogen 1,2-dimethylhydrazine]. (1978) (0)
- Symposium: Target DNA (1985) (0)
- Tumours IV (1997) (0)
- [Isolated infarctions in the optic radiation]. (1966) (0)
- [An interview with Paul Kleihues. Interview by Giuseppe Lojacono]. (1995) (0)
- [Cellular proliferation and protein synthesis of the neuroglia in experimental brain edema]. (1968) (0)
- [Histochemical, autoradiographic and electron microscopic aspects on the development of nerve cells]. (1967) (0)
- 1997 Volume Twenty‐three Contents (1997) (0)
- In Memoriam (1975) (0)
- Structural DNA Modifications and DNA Repair in Organ-Specific Tumor Induction (2020) (0)
- [DNA synthesis in neuroglia in experimental brain edema]. (1967) (0)
- Genetic Pathways in the Evolution of Gliomas (2005) (0)
- Pten Multations in Glioblastoma Subtypes (1998) (0)
- Volume contents (2004) (0)
- Response from: I. Rajower, A.J. Sasco and P. Kleihues (1997) (0)
- Pseudoventricle Formed in Grafted Neural Tissue and a New Hydrocephalic Model Using the Neural Transplant Method (Part 2) (1990) (0)
- Alkylation of porcine nucleic acids following intravenous and intragastric application of N-methyl-N-nitrosourea (1973) (0)
- [The pattern of cerebral involvement in encephalitides of the herpes simplex type]. (1969) (0)
- Short Communication Molecular Classification of Low-Grade Diffuse Gliomas (2010) (0)
- Short Communication Genetic Profile of Gliosarcomas (2000) (0)
- Induction of Cutaneous Melanocytic Tumours by N-Ethyl-N-Nitrosourea in the Mongolian Gerbil (Meriones Unguiculatus) (1986) (0)
- Primary and secondary glioblastomas: From concept to clinical diagnosis 1 (2005) (0)
- STUDIES ON THE MECHANISM OF NEURO-ONCOGENESIS BY POLYCYCLIC AROMATIC HYDROCARBONS (1978) (0)
- Over 1,000 Subscribers and Medline too (1994) (0)
- Advances in Brief p 53 Mutations Are Associated with 17 p Allelic Loss in Grade II and Grade III Astrocytoma 1 (2006) (0)
- Oral session I: Tumours (2004) (0)
- Oncogene Complementation in Fetal Brain Transplants1 (2006) (0)
- Abstracts for the Tenth International Conference on Brain Tumour Research and Therapy (2005) (0)
- Short Communication APC Mutations in Sporadic Medulloblastomas (2000) (0)
- The etiology of human cancers. (1996) (0)
- The British Neuropathological Society (2004) (0)
- Adrenal cortical carcinoma. WHO Classification of Tumours (2004) (0)
- Erwin G. Van Meir (ed): CNS cancer: Models, markers, prognostic factors, targets, and therapeutic approaches (2009) (0)
- Tumours of the Endocrine Organ (2004) (0)
- [Medulloblastoma therapy studies MBL 80 and MED 84 of the Society of Pediatric Oncology and the Société Internationale d'Oncologie Pédiatrique (SIOP)]. (1987) (0)
- Effects of ethanol and various alcoholic beverages on the formation of O 6-methyldeoxyguanosine from concurrently administered N-nitrosomethylbenzylamine in rats : a dose — response study (2005) (0)
- [Pathogenesis and pathological anatomy of arterial cerebral circulatory disorders]. (1969) (0)
- [On the development of skeletal muscle fibers]. (1967) (0)
- [Functional morphology of brown fatty tissue]. (1969) (0)
- A novel P53 germline mutation associated with a familial brain tumour syndrome (1994) (0)
- USE OF AN INTRACEREBRAL GRAFTING TECHNIQUE TO STUDY DIFFERENTIATION AND SELECTIVE VULNERABILITY OF CEREBELLAR NEURONS (1985) (0)
- [Effect of a single dose of N-methyl-N-nitrosourea on nucleic acid synthesis in vivo]. (1969) (0)
- Reply to Dr. Sass (2003) (0)
- SELECTIVE INDUCTION BY N‐NITROSOETHYLUREA (NEU) OF OLIGODENDROGLIOMAS IN PETAL FOREBRAIN GRAFTED INTO THE CAUDOPUTAMEN OF ADULT RATS: 122 (1987) (0)
- Gene Expression Profiling of Low-Grade Diffuse Astrocytomas by cDNA Arrays 1 (2000) (0)
- German-Austrian study on malignant supratentorial gliomas (1986) (0)
- SHORT COMMUNICATION Modulation of iV-nitrosomethylbenzylamiiie bioactivation by diallyl sulfide in vivo (2005) (0)
- Brain Pathology Goes Public (1992) (0)
- Advances in Brief p53 Mutations Are Associated with 17p Allelic Loss in Grade II and Grade III Astrocytoma1 (2006) (0)
- Abstract 4807:Brafmutations initiate the development of rat gliomas induced by postnatal exposure toN-ethyl-N-nitrosourea (ENU) (2017) (0)
- Modulation ofN-Nitrosomethylbenzylamine Metabolism in Rats by Concurrently Administered Ethanol and Diallyl Sulfide (1994) (0)
- DMA Methylation by Dimethylnitrosamine in the Mongolian Gerbil ( Mariones ungu / cu / atus ) : Indications of a Deficient , Noninducible Hepatic Repair System for O 6-Methylguanine 1 (2006) (0)
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What Schools Are Affiliated With Paul Kleihues?
Paul Kleihues is affiliated with the following schools: