Paul Knoepfler
#58,036
Most Influential Person Now
American biologist
Paul Knoepfler's AcademicInfluence.com Rankings
Paul Knoepflerbiology Degrees
Biology
#3858
World Rank
#5846
Historical Rank
#1523
USA Rank
Molecular Biology
#2552
World Rank
#2593
Historical Rank
#280
USA Rank
Download Badge
Biology
Paul Knoepfler's Degrees
- PhD Molecular Pathology University of California, San Diego
- Bachelors Biology University of California, Irvine
Similar Degrees You Can Earn
Why Is Paul Knoepfler Influential?
(Suggest an Edit or Addition)According to Wikipedia, Paul S. Knoepfler is an American biologist, writer, and blogger. He is a professor in the Department of Cell Biology and Human Anatomy, the Genome Center, and the Comprehensive Cancer Center at the University of California, Davis School of Medicine. In 2013, Knoepfler was named one of the 50 most influential people in the stem cell field.
Paul Knoepfler's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation. (2002) (530)
- Deconstructing Stem Cell Tumorigenicity: A Roadmap to Safe Regenerative Medicine (2009) (436)
- Sin Meets NuRD and Other Tails of Repression (1999) (397)
- Myc influences global chromatin structure (2006) (383)
- Pbx marks genes for activation by MyoD indicating a role for a homeodomain protein in establishing myogenic potential. (2004) (332)
- Selling Stem Cells in the USA: Assessing the Direct-to-Consumer Industry. (2016) (298)
- Hematopoietic stem cell function and survival depend on c-Myc and N-Myc activity. (2008) (279)
- Nmyc plays an essential role during lung development as a dosage-sensitive regulator of progenitor cell proliferation and differentiation (2005) (235)
- Meis1 and pKnox1 bind DNA cooperatively with Pbx1 utilizing an interaction surface disrupted in oncoprotein E2a-Pbx1. (1997) (218)
- The pentapeptide motif of Hox proteins is required for cooperative DNA binding with Pbx1, physically contacts Pbx1, and enhances DNA binding by Pbx1 (1995) (180)
- myc maintains embryonic stem cell pluripotency and self-renewal. (2010) (175)
- N-myc is an essential downstream effector of Shh signaling during both normal and neoplastic cerebellar growth. (2006) (160)
- Both Pbx1 and E2A-Pbx1 bind the DNA motif ATCAATCAA cooperatively with the products of multiple murine Hox genes, some of which are themselves oncogenes (1995) (157)
- Division and apoptosis of E2f-deficient retinal progenitors (2009) (156)
- N-Myc regulates a widespread euchromatic program in the human genome partially independent of its role as a classical transcription factor. (2008) (145)
- The Smad transcriptional corepressor TGIF recruits mSin3. (2001) (133)
- Why myc? An unexpected ingredient in the stem cell cocktail. (2008) (128)
- Myc goes global: new tricks for an old oncogene. (2007) (127)
- A conserved motif N-terminal to the DNA-binding domains of myogenic bHLH transcription factors mediates cooperative DNA binding with pbx-Meis1/Prep1. (1999) (127)
- Histone H3.3 mutations: a variant path to cancer. (2013) (122)
- Induced pluripotency and oncogenic transformation are related processes. (2013) (113)
- Myc stimulates B lymphocyte differentiation and amplifies calcium signaling (2007) (108)
- Meis1a suppresses differentiation by G-CSF and promotes proliferation by SCF: Potential mechanisms of cooperativity with Hoxa9 in myeloid leukemia (2001) (108)
- Wnt signaling and its downstream target N-myc regulate basal progenitors in the developing neocortex (2010) (95)
- Direct interaction of two homeoproteins, Homothorax and Extradenticle, is essential for EXD nuclear localization and function (2000) (95)
- Histone H3.3 regulates dynamic chromatin states during spermatogenesis (2014) (93)
- Neural Precursor Cycling at Sonic Speed: N-Myc Pedals, GSK-3 Brakes (2006) (89)
- From bench to FDA to bedside: US regulatory trends for new stem cell therapies. (2015) (86)
- N-Myc Regulates Expression of Pluripotency Genes in Neuroblastoma Including lif, klf2, klf4, and lin28b (2009) (84)
- Endogenous mammalian histone H3.3 exhibits chromatin-related functions during development (2013) (77)
- N-Myc and the cyclin-dependent kinase inhibitors p18Ink4c and p27Kip1 coordinately regulate cerebellar development. (2006) (74)
- Pbx-1 Hox heterodimers bind DNA on inseparable half-sites that permit intrinsic DNA binding specificity of the Hox partner at nucleotides 3' to a TAAT motif. (1996) (73)
- HBP1 and Mad1 repressors bind the Sin3 corepressor PAH2 domain with opposite helical orientations (2004) (72)
- Inducing iPSCs to escape the dish. (2011) (68)
- Induced Pluripotent Stem Cells Show Metabolomic Differences to Embryonic Stem Cells in Polyunsaturated Phosphatidylcholines and Primary Metabolism (2012) (67)
- HoxB8 requires its Pbx-interaction motif to block differentiation of primary myeloid progenitors and of most cell line models of myeloid differentiation (2001) (66)
- Reviewing post-publication peer review. (2015) (58)
- N-Myc and GCN5 Regulate Significantly Overlapping Transcriptional Programs in Neural Stem Cells (2012) (57)
- Acting locally and globally: Myc's ever-expanding roles on chromatin. (2009) (55)
- Activities of N-Myc in the developing limb link control of skeletal size with digit separation (2007) (49)
- An inhibitory switch derepressed by Pbx, Hox, and Meis/Prep1 partners regulates DNA-binding by Pbx1 and E2a-Pbx1 and is dispensable for myeloid immortalization by E2a-Pbx1 (1999) (49)
- The highest affinity DNA element bound by Pbx complexes in t(1;19) leukemic cells fails to mediate cooperative DNA-binding or cooperative transactivation by E2a-Pbx1 and Class I Hox proteins – evidence for selective targetting of E2a-Pbx1 to a subset of Pbx-recognition elements (1997) (48)
- N-myc Controls Proliferation, Morphogenesis, and Patterning of the Inner Ear (2011) (48)
- N-myc coordinates retinal growth with eye size during mouse development. (2008) (46)
- c-myc and N-myc promote active stem cell metabolism and cycling as architects of the developing brain (2010) (45)
- The FDA and the US direct-to-consumer marketplace for stem cell interventions: a temporal analysis. (2018) (45)
- Genomic binding and transcriptional regulation by the Drosophila Myc and Mnt transcription factors. (2005) (41)
- c- and N-myc Regulate Neural Precursor Cell Fate, Cell Cycle, and Metabolism to Direct Cerebellar Development (2010) (40)
- The Pbx family of proteins is strongly upregulated by a post-transcriptional mechanism during retinoic acid-induced differentiation of P19 embryonal carcinoma cells (1997) (37)
- Gene expression in a swine model of right ventricular hypertrophy: intercellular adhesion molecule, vascular endothelial growth factor and plasminogen activators are upregulated during pressure overload. (1995) (36)
- Myc and Miz-1 have coordinate genomic functions including targeting Hox genes in human embryonic stem cells (2011) (32)
- Identification of DPPA4 and DPPA2 as a novel family of pluripotency‐related oncogenes (2013) (30)
- Urokinase plasminogen activator activity is increased in the myocardium during coronary artery occlusion. (1995) (28)
- Reciprocal H3.3 gene editing identifies K27M and G34R mechanisms in pediatric glioma including NOTCH signaling (2020) (23)
- Epigenetic mechanisms of tumorigenicity manifesting in stem cells (2014) (22)
- Call for fellowship programs in stem cell-based regenerative and cellular medicine: new stem cell training is essential for physicians. (2013) (21)
- Gmo Sapiens: The Life-Changing Science Of Designer Babies (2015) (19)
- To CRISPR and beyond: the evolution of genome editing in stem cells. (2016) (16)
- The Stem Cell Hard Sell: Report from a Clinic's Patient Recruitment Seminar (2016) (15)
- Rapid change of a cohort of 570 unproven stem cell clinics in the USA over 3 years. (2019) (14)
- Key anticipated regulatory issues for clinical use of human induced pluripotent stem cells. (2012) (14)
- Miz-1 Activates Gene Expression via a Novel Consensus DNA Binding Motif (2014) (14)
- Constitutive gray hair in mice induced by melanocyte‐specific deletion of c‐Myc (2012) (12)
- Genomic functions of developmental pluripotency associated factor 4 (Dppa4) in pluripotent stem cells and cancer (2018) (12)
- CRISPR-mediated HDAC2 disruption identifies two distinct classes of target genes in human cells (2017) (10)
- ERBB3‐Binding Protein 1 (EBP1) Is a Novel Developmental Pluripotency‐Associated‐4 (DPPA4) Cofactor in Human Pluripotent Cells (2018) (10)
- Too Much Carrot and Not Enough Stick in New Stem Cell Oversight Trends. (2018) (9)
- Chromatin immunoprecipitation assays for Myc and N-Myc. (2013) (9)
- When patients reach out, scientists should reach back carefully (2016) (8)
- Behavior of Xeno-Transplanted Undifferentiated Human Induced Pluripotent Stem Cells Is Impacted by Microenvironment Without Evidence of Tumors. (2017) (7)
- Utf1: Goldilocks for ESC bivalency. (2012) (6)
- Transduction of Human Cells with Polymer-complexed Ecotropic Lentivirus for Enhanced Biosafety (2011) (6)
- Key action items for the stem cell field: looking ahead to 2014. (2013) (5)
- Mapping and driving the stem cell ecosystem. (2018) (5)
- Stem cells on the brain. (2008) (4)
- Myc binds the pluripotency factor Utf1 through the basic-helix-loop-helix leucine zipper domain. (2013) (4)
- Title Endogenous mammalian histone H 3 . 3 exhibits chromatin-related functions during development (2013) (4)
- Stem Cells: An Insider's Guide (2013) (4)
- C-myc and N-myc in the developing brain (2010) (3)
- Anticipated impact of stem cell and other cellular medicine clinical trials for COVID-19 (2021) (3)
- Histone H3.3 K27M chromatin functions implicate a network of neurodevelopmental factors including ASCL1 and NEUROD1 in DIPG (2022) (3)
- My year as a stem-cell blogger (2011) (2)
- Gene editing: sloppy definitions mislead (2018) (1)
- Messing with Mother Nature: The First GMO Sapiens (2015) (1)
- Journal club (2009) (1)
- Arrestin' the hedgehog: Shh limits its own signaling via β-Arrestin1 (2010) (1)
- The Molecular Circuitry Underlying Pluripotency in Embryonic and Induced Pluripotent Stem Cells (2019) (1)
- Aging: The Stem Cell Connection (2013) (0)
- PDTM-26. NOVEL SHARED AND DISTINCT EPIGENOMIC MECHANISMS OF G34R AND K27M MUTATIONS IN CHILDHOOD GLIOMA (2019) (0)
- Conclusion: The Future of Stem Cells (2013) (0)
- Stem Cell Models: Past, Present, and Future (2013) (0)
- Scientists: you really need to get out of the lab more (2013) (0)
- DIPG-09. CRISPR GENE EDITING OF ENDOGENOUS MUTANT FORMS OF H3.3 DEFINES ONCOHISTONE MECHANISMS AND NEW THERAPEUTIC APPROACHES (2019) (0)
- GMO Sapiens Today and Tomorrow (2015) (0)
- Myc Supports Self-Renewal of Basal Cells in the Esophageal Epithelium (2022) (0)
- Climate: De-fogged (2009) (0)
- Are We There Yet? How Stem Cells Might Work to Treat Specific Diseases (2013) (0)
- Automation of Library Preparation for High-resolution ChIP-seq Profiling. (2013) (0)
- Eugenics and Transhumanism (2015) (0)
- DIY Guide to Creating GMO Sapiens (2015) (0)
- The Stem Cell Hard Sell: Report From a Clinic's Patient Recruitment Seminar. (2016) (0)
- Getting Your Stem Cell Geek On (2013) (0)
- Stem Cell Tests for Humanity (2013) (0)
- Solution Structure of HBP1 SID-mSin3A PAH2 Complex (2004) (0)
- Build-a-Baby Better via Genetics (2015) (0)
- The death of MyMouseHouse: lessons for systems for the efficient management of mouse colonies (2010) (0)
- are themselves oncogenes . of multiple murine Hox genes , some of which ATCAATCAA cooperatively with the products Both Pbx 1 and E 2 A-Pbx 1 bind the DNA motif (1995) (0)
- A knockout‐first model of H3f3a gene targeting leads to developmental lethality (2023) (0)
- Histone H3.3 K27M chromatin functions implicate a network of neurodevelopmental factors including ASCL1 and NEUROD1 in DIPG (2022) (0)
- An Introduction to Playing God (2015) (0)
- Cultural Views on Human Genetic Modification (2015) (0)
- Meet Your Stem Cells (2013) (0)
- How to Build a Dragon or Die Trying (2018) (0)
- Stem Cells for Profit: An Ethical Spectrum (2013) (0)
- Reciprocal H3.3 gene editing identifies K27M and G34R mechanisms in pediatric glioma including NOTCH signaling (2020) (0)
- during both Normal and Neoplastic Cerebellar Growth Is an Essential Downstream Effector of Shh Signaling myc (0)
- Endogenous mammalian histone H3.3 exhibits chromatin-related functions during development (2013) (0)
- Review of Stem Cell Dialogues by Sheldon Krimsky1 (2016) (0)
- DPPA2, DPPA4, and other DPPA factor epigenomic functions in cell fate and cancer (2021) (0)
- The Types of Stem Cells and Their Clinical Potential (2013) (0)
- All in the Family: An Insider’s Tale of Two Stem Cells and a Black Sheep (2013) (0)
- Law and Order Stem Cells (2013) (0)
- Stem Cell Treatments: Applications and Obstacles (2013) (0)
- Patient Bill of Rights and Guide to Stem Cell Treatments (2013) (0)
- Stem Cell Cosmetics: More Than Skin Deep? (2013) (0)
- Gene editing: sloppy definitions mislead (2018) (0)
- Stem cell models help crack regional oncohistone codes driving childhood gliomas. (2021) (0)
- The Birth and Explosive Growth of GMOs (2015) (0)
This paper list is powered by the following services:
Other Resources About Paul Knoepfler
What Schools Are Affiliated With Paul Knoepfler?
Paul Knoepfler is affiliated with the following schools:
