Paul Nurse
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Nobel prize winning British biochemist
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Paul Nursebiology Degrees
Biology
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#152
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Genetics
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Biochemistry
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Biology
Paul Nurse's Degrees
- PhD Genetics University of East Anglia
Why Is Paul Nurse Influential?
(Suggest an Edit or Addition)According to Wikipedia, Sir Paul Maxime Nurse is an English geneticist, former President of the Royal Society and Chief Executive and Director of the Francis Crick Institute. He was awarded the 2001 Nobel Prize in Physiology or Medicine, along with Leland Hartwell and Tim Hunt, for their discoveries of protein molecules that control the division of cells in the cell cycle.
Paul Nurse's Published Works
Published Works
- Molecular genetic analysis of fission yeast Schizosaccharomyces pombe. (1991) (3480)
- Universal control mechanism regulating onset of M-phase (1990) (2778)
- The genome sequence of Schizosaccharomyces pombe (2002) (1656)
- Animal cell cycles and their control. (1992) (1269)
- Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis (1989) (1154)
- Complementation used to clone a human homologue of the fission yeast cell cycle control gene cdc2 (1987) (1024)
- Negative regulation of mitosis by wee1 +, a gene encoding a protein kinase homolog (1987) (938)
- cdc25 + functions as an inducer in the mitotic control of fission yeast (1986) (932)
- Purified maturation-promoting factor contains the product of a Xenopus homolog of the fission yeast cell cycle control gene cdc2 + (1988) (824)
- Genetic control of cell size at cell division in yeast (1975) (816)
- Gene required in G1 for commitment to cell cycle and in G2 for control of mitosis in fission yeast (1981) (704)
- Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe (2010) (648)
- Ordering S phase and M phase in the cell cycle (1994) (637)
- A Long Twentieth Century of the Cell Cycle and Beyond (2000) (622)
- Cohesin Rec8 is required for reductional chromosome segregation at meiosis (1999) (547)
- Periodic gene expression program of the fission yeast cell cycle (2004) (527)
- Regulation of p34cdc2 protein kinase during mitosis (1989) (525)
- Genetic control of the cell division cycle in the fission yeast Schizosaccharomyces pombe (1976) (510)
- The Cdt1 protein is required to license DNA for replication in fission yeast (2000) (507)
- Regulatory phosphorylation of the p34cdc2 protein kinase in vertebrates. (1991) (502)
- Growth in cell length in the fission yeast Schizosaccharomyces pombe. (1985) (487)
- The fission yeast cdc18 + gene product couples S phase to START and mitosis (1993) (465)
- Mutation of fission yeast cell cycle control genes abolishes dependence of mitosis on DNA replication (1990) (451)
- The cell cycle control gene cdc2 + of fission yeast encodes a protein kinase potentially regulated by phosphorylation (1986) (446)
- cdc12p, a Protein Required for Cytokinesis in Fission Yeast, Is a Component of the Cell Division Ring and Interacts with Profilin (1997) (440)
- Control of cell size at division in fission yeast by a growth-modulated size control over nuclear division. (1977) (427)
- Chk1 is a wee1 kinase in the G2 DNA damage checkpoint inhibiting cdc2 by Y15 phosphorylation (1997) (421)
- Temporal order of S phase and mitosis in fission yeast is determined by the state of the p34 cdc2 -mitotic B cyclin complex (1994) (404)
- Phosphorylation at Thr167 is required for Schizosaccharomyces pombe p34cdc2 function. (1991) (402)
- Regulatory genes controlling mitosis in the fission yeast Schizosaccharomyces pombe. (1980) (381)
- Functionally homologous cell cycle control genes in budding and fission yeast (1982) (377)
- A spatial gradient coordinates cell size and mitotic entry in fission yeast (2009) (375)
- Fission yeast genes involved in coupling mitosis to completion of DNA replication. (1992) (372)
- Driving the cell cycle with a minimal CDK control network (2010) (359)
- p34cdc2 is located in both nucleus and cytoplasm; part is centrosomally associated at G2/M and enters vesicles at anaphase. (1989) (357)
- tea1 and the Microtubular Cytoskeleton Are Important for Generating Global Spatial Order within the Fission Yeast Cell (1997) (355)
- Substrates for p34 cdc2 : In vivo veritas? (1990) (350)
- Involvement of p34cdc2 in establishing the dependency of S phase on mitosis (1991) (347)
- High-frequency transformation of the fission yeast Schizosaccharomyces pombe (1981) (336)
- Isolation and characterization of fission yeast mutants defective in the assembly and placement of the contractile actin ring. (1996) (333)
- Nuclear size control in fission yeast (2007) (332)
- Cell cycle regulation in the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe. (1991) (331)
- A single fission yeast mitotic cyclin B p34cdc2 kinase promotes both S‐phase and mitosis in the absence of G1 cyclins. (1996) (303)
- A quantitative model for the cdc2 control of S phase and mitosis in fission yeast. (1996) (300)
- Activation at M-phase of a protein kinase encoded by a starfish homologue of the cell cycle control gene cdc2+ (1988) (297)
- The mitotic inducer nim1 + functions in a regulatory network of protein kinase homologs controlling the initiation of mitosis (1987) (297)
- Fission yeast Taz1 protein is required for meiotic telomere clustering and recombination (1998) (291)
- CLIP170-like tip1p Spatially Organizes Microtubular Dynamics in Fission Yeast (2000) (284)
- p65 cdc18 Plays a major role controlling the initiation of DNA replication in fission yeast (1995) (275)
- Regulation of progression through the Gl phase of the cell cycle by the rum1 + gene (1994) (274)
- Dephosphorylation and activation of Xenopusp34cdc2 protein kinase during the cell cycle (1989) (263)
- Mammalian growth-associated H1 histone kinase: a homolog of cdc2+/CDC28 protein kinases controlling mitotic entry in yeast and frog cells (1989) (238)
- Fission yeast orb6, a ser/thr protein kinase related to mammalian rho kinase and myotonic dystrophy kinase, is required for maintenance of cell polarity and coordinates cell morphogenesis with the cell cycle. (1998) (219)
- CDK Substrate Phosphorylation and Ordering the Cell Cycle (2016) (215)
- Fission yeast cell morphogenesis: identification of new genes and analysis of their role during the cell cycle (1995) (214)
- Cloning and sequencing of the cyclin-related cdc13+ gene and a cytological study of its role in fission yeast mitosis. (1988) (214)
- Genome‐wide characterization of fission yeast DNA replication origins (2006) (211)
- twine, a cdc25 homolog that functions in the male and female germline of drosophila (1992) (210)
- Regulation of mitosis by cyclic accumulation of p80cdc25 mitotic inducer in fission yeast (1990) (208)
- Regulation of progression through the G1 phase of the cell cycle by the rum1+ gene (1994) (205)
- Checkpoint Pathways Come of Age (1997) (205)
- A journey into space (2001) (202)
- Controls over the timing of DNA replication during the cell cycle of fission yeast. (1977) (202)
- Life, logic and information (2008) (202)
- The FT210 cell line is a mouse G2 phase mutant with a temperature-sensitive CDC2 gene product (1990) (201)
- p25rum1 orders S phase and mitosis by acting as an inhibitor of the p34cdc2 mitotic kinase (1995) (199)
- What determines cell size? (2012) (195)
- TOR signalling regulates mitotic commitment through the stress MAP kinase pathway and the Polo and Cdc2 kinases (2007) (185)
- Cloning, sequencing and transcriptional control of the Schizosaccharomyces pombe cdc10 ‘start’ gene. (1985) (179)
- Coupling M phase and S phase: Controls maintaining the dependence of mitosis on chromosome replication (1991) (176)
- Genetic analysis of cell morphogenesis in fission yeast‐‐a role for casein kinase II in the establishment of polarized growth. (1994) (173)
- Microtubules mediate mitochondrial distribution in fission yeast. (1996) (172)
- Schizosaccharomyces pombe and saccharomyces cerevisiae: A look at yeasts divided (1986) (172)
- Regulated expression and phosphorylation of a possible mammalian cell-cycle control protein (1988) (171)
- cut11(+): A gene required for cell cycle-dependent spindle pole body anchoring in the nuclear envelope and bipolar spindle formation in Schizosaccharomyces pombe. (1998) (169)
- A cdc2-like protein is involved in the initiation of DNA replication in Xenopus egg extracts (1990) (166)
- Uncontrolled septation in a cell division cycle mutant of the fission yeast Schizosaccharomyces pombe (1979) (157)
- Regulation of Cell Polarity by Microtubules in Fission Yeast (1998) (156)
- Complementation of the mitotic activator, p80cdc25, by a human protein-tyrosine phosphatase (1990) (153)
- NOBEL LECTURE: Cyclin Dependent Kinases and Cell Cycle Control (2002) (150)
- Pre-meiotic S phase is linked to reductional chromosome segregation and recombination (2001) (149)
- Cell cycle control genes in fission yeast and mammalian cells. (1988) (148)
- Cell division cycle mutants altered in DNA replication and mitosis in the fission yeast Schizosaccharomyces pombe (2004) (147)
- How Fission Yeast Fission in the Middle (1996) (145)
- Tea2p Is a Kinesin-like Protein Required to Generate Polarized Growth in Fission Yeast (2000) (145)
- Tea2p kinesin is involved in spatial microtubule organization by transporting tip1p on microtubules. (2004) (144)
- Control of the timing of cell division in fission yeast. Cell size mutants reveal a second control pathway. (1978) (144)
- suc1 is an essential gene involved in both the cell cycle and growth in fission yeast (1986) (143)
- Establishing the Program of Origin Firing during S Phase in Fission Yeast (2009) (142)
- A genome-wide resource of cell cycle and cell shape genes of fission yeast (2013) (138)
- Cell cycle control genes in yeast (1985) (136)
- Premature chromatin condensation upon accumulation of NIMA. (1994) (130)
- Complementation of fission yeast cdc2ts and cdc25ts mutants identifies two cell cycle genes from Drosophila: a cdc2 homologue and string. (1990) (129)
- Fission yeast Schizosaccharomyces pombe correctly excises a mammalian RNA transcript intervening sequence (1985) (129)
- A fission yeast RCC1‐related protein is required for the mitosis to interphase transition. (1994) (126)
- Targeted movement of cell end factors in fission yeast (2003) (125)
- The ORC1 homolog orp1 in fission yeast plays a key role in regulating onset of S phase. (1996) (125)
- Cdt1 and geminin are down-regulated upon cell cycle exit and are over-expressed in cancer-derived cell lines. (2004) (123)
- DNA polymerase alpha, a component of the replication initiation complex, is essential for the checkpoint coupling S phase to mitosis in fission yeast. (1995) (121)
- A Coordinated Global Control over Cellular Transcription (2010) (119)
- Function of Cdc2p‐dependent Bub1p phosphorylation and Bub1p kinase activity in the mitotic and meiotic spindle checkpoint (2003) (118)
- Regulating S Phase: CDKs, Licensing and Proteolysis (1996) (118)
- Isolation and analysis of the fission yeast gene encoding polymerase delta accessory protein PCNA. (1992) (118)
- Genetics of the fission yeast Schizosaccharomyces pombe. (1992) (114)
- The fission yeast gene pmt1+ encodes a DNA methyltransferase homologue. (1995) (114)
- Stable Association of Mitotic Cyclin B/Cdc2 to Replication Origins Prevents Endoreduplication (2002) (113)
- Cyclin Dependent Kinases and Cell Cycle Control (Nobel Lecture) (2002) (110)
- Expression of Cdc18/Cdc6 and Cdt1 during G2 phase induces initiation of DNA replication (2001) (110)
- Regulation of the eukaryotic cell cycle. (1997) (110)
- Fission yeast Pom1p kinase activity is cell cycle regulated and essential for cellular symmetry during growth and division (2001) (108)
- The fission yeast Cdc1 protein, a homologue of the small subunit of DNA polymerase delta, binds to Pol3 and Cdc27. (1996) (104)
- Expression of the SV40 promoter in fission yeast: Identification and characterization of an AP-1-like factor (1988) (103)
- Vectors for the construction of gene banks and the integration of cloned genes in Schizosaccharomyces pombe and Saccharomyces cerevisiae. (1986) (101)
- DNA replication and damage checkpoints and meiotic cell cycle controls in the fission and budding yeasts. (2000) (101)
- Basic Medical Research Award (1998) (101)
- Spatial Control of Cytokinesis by Cdr2 Kinase and Mid1/Anillin Nuclear Export (2009) (99)
- The effect of cell mass on the cell cycle timing and duration of S-phase in fission yeast. (1979) (98)
- In vivo localisation of fission yeast cyclin-dependent kinase cdc2p and cyclin B cdc13p during mitosis and meiosis. (2001) (95)
- Roles of fission yeast tea1p in the localization of polarity factors and in organizing the microtubular cytoskeleton (2002) (95)
- Cell Division Intersects with Cell Geometry (2010) (92)
- Mutants of the fission yeast Schizosaccharomyces pombe which alter the shift between cell proliferation and sporulation (1985) (91)
- The fission yeast cell cycle control gene cdc2: isolation of a sequence suc1 that suppresses cdc2 mutant function (1986) (91)
- Equatorial Retention of the Contractile Actin Ring by Microtubules During Cytokinesis (2003) (89)
- Schizosaccharomyces pombe cdc20+ encodes DNA polymerase epsilon and is required for chromosomal replication but not for the S phase checkpoint. (1997) (89)
- Negative Regulation of Mitosis (1987) (89)
- A fission yeast general translation factor reveals links between protein synthesis and cell cycle controls. (2000) (84)
- Analysis of a histone H2A variant from fission yeast: evidence for a role in chromosome stability (1994) (83)
- Construction of a Schizosaccharomyces pombe gene bank in a yeast bacterial shuttle vector and its use to isolate genes by complementation (2004) (83)
- Mutants altered in the control co-ordinating cell division with cell growth in the fission yeast Schizosaccharomyces pombe (1978) (81)
- Identification of fission yeast nuclear markers using random polypeptide fusions with green fluorescent protein. (1996) (81)
- APC/C Dysfunction Limits Excessive Cancer Chromosomal Instability. (2017) (80)
- Schizosaccharomyces pombe essential genes: a pilot study. (2003) (79)
- Genetic and molecular analysis of cdr1/nim1 in Schizosaccharomyces pombe. (1991) (79)
- Periodic transcription as a means of regulating gene expression during the cell cycle: contrasting modes of expression of DNA ligase genes in budding and fission yeast. (1986) (78)
- Self-organization of interphase microtubule arrays in fission yeast (2006) (77)
- Spatial control of Cdc42 activation determines cell width in fission yeast (2011) (76)
- Identification of a Gl-type cyclin puc1 + in the fission yeast Schizosaccharomyces pombe (1991) (76)
- Control of the higher eukaryote cell cycle by p34cdc2 homologues. (1989) (76)
- The fission yeast cdc19+ gene encodes a member of the MCM family of replication proteins. (1994) (76)
- Pom1 and cell size homeostasis in fission yeast (2013) (74)
- The Cell in an Era of Systems Biology (2011) (72)
- Novel cell cycle control of RNA synthesis in yeast (1978) (71)
- The crystal structure of p13suc1, a p34cdc2‐interacting cell cycle control protein. (1995) (71)
- Transcription of the cdc2 cell cycle control gene of the fission yeast Schizosaccharomyces pombe (1986) (71)
- Cdc18 transcription and proteolysis couple S phase to passage through mitosis (1998) (71)
- Meiotic DNA replication checkpoint control in fission yeast. (1999) (69)
- Fission yeast Fizzy‐related protein srw1p is a G1‐specific promoter of mitotic cyclin B degradation (2000) (69)
- Cell Cycle Regulation in Yeast (1986) (67)
- Discovering the poles in yeast. (1998) (67)
- The fission yeast origin recognition complex is constitutively associated with chromatin and is differentially modified through the cell cycle. (1999) (66)
- Fission yeast morphogenesis--posing the problems. (1994) (64)
- Maturation-promoting factor and the regulation of the cell cycle (1989) (64)
- Systems biology: Understanding cells (2003) (62)
- Unravelling nuclear size control (2019) (62)
- Quantitative Control of Protein S-Palmitoylation Regulates Meiotic Entry in Fission Yeast (2013) (62)
- Photoactivation of green fluorescent protein (1997) (62)
- A pre‐start checkpoint preventing mitosis in fission yeast acts independently of p34cdc2 tyrosine phosphorylation. (1995) (61)
- Control of S‐phase periodic transcription in the fission yeast mitotic cycle (1997) (61)
- The microbial cell cycle (1984) (61)
- Fission yeast retrotransposon Tf1 integration is targeted to 5' ends of open reading frames. (2000) (60)
- Mitotic checkpoint control in fission yeast. (1991) (59)
- Feedback regulation of the MBF transcription factor by cyclin Cig2 (2001) (59)
- Fission yeast pheromone blocks S‐phase by inhibiting the G1 cyclin B–p34cdc2 kinase (1997) (59)
- Regulation of premeiotic S phase and recombination-related double-strand DNA breaks during meiosis in fission yeast (2001) (58)
- Clues to action of cdc25 protein (1991) (57)
- Sizing up to divide: mitotic cell-size control in fission yeast. (2015) (57)
- A systematic screen reveals new elements acting at the G2/M cell cycle control (2012) (56)
- p34cdc2 acts as a lamin kinase in fission yeast (1991) (56)
- The Kinesin Klp2 Mediates Polarization of Interphase Microtubules in Fission Yeast (2005) (55)
- Quantitative Phosphoproteomics Reveals the Signaling Dynamics of Cell-Cycle Kinases in the Fission Yeast Schizosaccharomyces pombe (2018) (54)
- Analysis of the Schizosaccharomyces pombe cyclin puc1: evidence for a role in cell cycle exit. (1994) (53)
- Potent, Reversible, and Specific Chemical Inhibitors of Eukaryotic Ribosome Biogenesis (2016) (52)
- Tea3p Is a Cell End Marker Activating Polarized Growth in Schizosaccharomyces pombe (2002) (50)
- Yeast cells can enter a quiescent state through G1, S, G2, or M phase of the cell cycle. (1993) (50)
- Fission Yeast Cells Undergo Nuclear Division in the Absence of Spindle Microtubules (2010) (50)
- Cyclins of the fission yeast Schizosaccharomyces pombe. (1995) (50)
- The protein kinase kin1, the fission yeast orthologue of mammalian MARK/PAR‐1, localises to new cell ends after mitosis and is important for bipolar growth (2003) (49)
- A Meiosis-Specific Cyclin Regulated by Splicing Is Required for Proper Progression through Meiosis (2005) (49)
- Molecular rearrangement of mating-type genes in fission yeast (1982) (48)
- Cyclin B proteolysis and the cyclin-dependent kinase inhibitor rum1p are required for pheromone-induced G1 arrest in fission yeast. (1998) (48)
- A systematic genomic screen implicates nucleocytoplasmic transport and membrane growth in nuclear size control (2017) (47)
- Cyclin Dependent Kinases and Cell Cycle Control (2002) (47)
- The spatial and temporal organization of origin firing during the S-phase of fission yeast (2015) (47)
- p25rum1 promotes proteolysis of the mitotic B‐cyclin p56cdc13 during G1 of the fission yeast cell cycle (1997) (46)
- Cell cycle genes of the fission yeast. (1987) (45)
- Mutational analysis supports a structural model for the cell cycle protein kinase p34. (1994) (45)
- Altered patterns of ribonucleic acid synthesis during the cell cycle: a mechanism compensating for variation in gene concentration. (1979) (45)
- The Incredible Life and Times of Biological Cells (2000) (45)
- The p150-Glued Ssm4p regulates microtubular dynamics and nuclear movement in fission yeast (2004) (44)
- The European Cancer Patient’s Bill of Rights, update and implementation 2016 (2016) (44)
- Characterization of the fission yeast cdc10+ protein that is required for commitment to the cell cycle. (1989) (44)
- License Withheld--Geminin Blocks DNA Replication (2000) (43)
- Molecular Combing of Single DNA Molecules on the 10 Megabase Scale (2016) (43)
- End4/Sla2 is involved in establishment of a new growth zone in Schizosaccharomyces pombe (2005) (43)
- The G1/S cyclin Cig2p during meiosis in fission yeast. (2002) (42)
- Nuclear membrane protein Lem2 regulates nuclear size through membrane flow (2019) (41)
- Cdk1 and cell morphology: connections and directions. (2009) (41)
- Yeast as a model system for understanding the control of DNA replication in eukaryotes (1990) (41)
- Cdc18 enforces long-term maintenance of the S phase checkpoint by anchoring the Rad3-Rad26 complex to chromatin. (2007) (40)
- Model organism databases: essential resources that need the support of both funders and users (2016) (39)
- S. pombe genome deletion project: An update (2010) (38)
- De Novo Growth Zone Formation from Fission Yeast Spheroplasts (2011) (38)
- Cell cycle control — both deterministic and probabilistic? (1980) (38)
- Mis-specification of cortical identity in a fission yeast PAK mutant (1999) (37)
- A single cyclin–CDK complex is sufficient for both mitotic and meiotic progression in fission yeast (2015) (37)
- A review of mitosis in the fission yeast Schizosaccharomyces pombe. (1989) (37)
- Investigations into the control of cell form and polarity: the use of morphological mutants in fission yeast. (1993) (37)
- Introduction to Fission Yeast as a Model System. (2018) (36)
- Analyzing fission yeast multidrug resistance mechanisms to develop a genetically tractable model system for chemical biology. (2012) (36)
- Noisy Cell-Size-Correlated Expression of Cyclin B Drives Probabilistic Cell-Size Homeostasis in Fission Yeast (2019) (36)
- Cell cycle. License withheld--geminin blocks DNA replication. (2000) (35)
- Ste20/GCK kinase Nak1/Orb3 polarizes the actin cytoskeleton in fission yeast during the cell cycle (2005) (34)
- Ensuring a successful UK research endeavour : a review of the UK research councils (2015) (34)
- Regulation of the cell cycle timing of Start in fission yeast by the rum1+ gene (1994) (33)
- Global control of cell growth in fission yeast and its coordination with the cell cycle. (2012) (33)
- The cell cycle and suc1: from structure to function? (1995) (33)
- A note on the evolution of meiosis. (1991) (32)
- Dominant mutants identify new roles for p34cdc2 in mitosis. (1995) (32)
- Interaction of cdc2 and rum1 regulates Start and S-phase in fission yeast. (1995) (32)
- Cyclins and cell cycle control (1991) (31)
- Cdc18/CDC6 activates the Rad3-dependent checkpoint in the fission yeast (2007) (30)
- New concepts in fission yeast morphogenesis. (2000) (30)
- Cdc18p can block mitosis by two independent mechanisms. (1998) (30)
- A dominant negative allele of p34cdc2 shows altered phosphoamino acid content and sequesters p56cdc13 cyclin (1992) (30)
- Maintenance of replication forks and the S-phase checkpoint by Cdc18p and Orp1p (2002) (30)
- Molecular cloning and sequence analysis of mutant alleles of the fission yeast cdc2 protein kinase gene: Implications for cdc2+ protein structure and function (1989) (30)
- Nuclear envelope expansion is crucial for proper chromosomal segregation during a closed mitosis (2016) (29)
- A novel S phase inhibitor in fission yeast. (1996) (29)
- Checkpoints in the cell cycle of fission yeast. (1995) (29)
- Microtubules offset growth site from the cell centre in fission yeast (2007) (29)
- A study of integrative transformation in Schizosaccharomyces pombe (1993) (28)
- G1/S CDK is inhibited to restrain mitotic onset when DNA replication is blocked in fission yeast (2002) (27)
- How cells know they are in G1 or G2. (1994) (27)
- Cloning and characterization of the Schizosaccharomyces pombe DNA ligase gene CDC17. (1986) (25)
- Coupling DNA replication to the cell cycle. (1993) (25)
- Cold-sensitive mutants of p34dc2 that suppress a mitotic catastrophe phenotype in fission yeast (1992) (24)
- The nuclear rim protein Amo1 is required for proper microtubule cytoskeleton organisation in fission yeast (2005) (24)
- A systematic genetic screen identifies essential factors involved in nuclear size control (2019) (24)
- Identification of a G1-type cyclin puc1+ in the fission yeast Schizosaccharomyces pombe. (1991) (24)
- Cyclin-Dependent Kinases and Cell Cycle Control (Nobel Lecture). (2002) (24)
- A novel mutant allele of the chromatin-bound fission yeast checkpoint protein Rad17 separates the DNA structure checkpoints. (2000) (23)
- Cyclin-Dependent Kinase Inhibits Reinitiation of a Normal S-Phase Program during G2 in Fission Yeast (2009) (23)
- G1 regulation and checkpoints operating around START in fission yeast (1995) (23)
- Different mechanisms of cell polarisation in vegetative and shmooing growth in fission yeast. (2002) (22)
- Isolation, characterisation and molecular cloning of new mutant alleles of the fission yeast p34cdc2+ protein kinase gene: identification of temperature-sensitive G2-arresting alleles (1991) (22)
- Cloning and characterization of two genes restoring acid phosphatase activity in pho1- mutants of Schizosaccharomyces pombe. (1985) (22)
- Replication Origin Selection Regulates the Distribution of Meiotic Recombination (2014) (21)
- Histone transcription in cell cycle mutants of fission yeast (1987) (21)
- Finishing the cell cycle: control of mitosis and cytokinesis in fission yeast. (1993) (21)
- The Florey Lecture, 1990. How is the cell division cycle regulated? (1991) (21)
- US Biomedical Research under Siege (2006) (21)
- Role of Tea1p, Tea3p and Pom1p in the determination of cell ends in Schizosaccharomyces pombe (2003) (20)
- Eukaryotic Cell-Cycle Control (1992) (19)
- Analysis of the significance of a periodic, cell size-controlled doubling in rates of macromolecular synthesis for the control of balanced exponential growth of fission yeast cells. (1979) (19)
- Arginase and sucrase potential in the fission yeast Schizosaccharomyces pombe. (1980) (19)
- Role of fission yeast primase catalytic subunit in the replication checkpoint. (2001) (18)
- Controls of cell proliferation in yeast and animals. (1990) (18)
- Study of the higher eukaryotic gene function CDK2 using fission yeast. (1994) (18)
- Mammalian phosphatidylinositol 3'-kinase induces a lethal phenotype on expression in Schizosaccharomyces pombe; comparison with the VPS34 gene product. (1994) (17)
- Interphase microtubule bundles use global cell shape to guide spindle alignment in fission yeast (2008) (17)
- Regulation of the cell cycle timing of mitosis (1989) (16)
- The CCR4-NOT Complex Is Implicated in the Viability of Aneuploid Yeasts (2012) (16)
- A diffusion model for the coordination of DNA replication in Schizosaccharomyces pombe (2016) (16)
- Reductionism and explanation in cell biology. (1998) (16)
- Checkpoints and spindles (1991) (16)
- Cell-Cycle Control in Yeasts (1977) (15)
- Bring on the phosphatases (1993) (15)
- The great ideas of biology. (2003) (15)
- An analysis of cancer research funding in the UK (2003) (15)
- A chemical biology strategy to analyze rheostat-like protein kinase-dependent regulation. (2013) (14)
- A genome–wide screen to identify genes controlling the rate of entry into mitosis in fission yeast (2016) (14)
- The Hydrophobic Patch Directs Cyclin B to Centrosomes to Promote Global CDK Phosphorylation at Mitosis (2020) (14)
- Investigations into the control of cell form and polarity: the use of morphological mutants in fission yeast. (1993) (13)
- The Josef Steiner Lecture:CDKs and cell‐cycle control in fission yeast: Relevance to other eukaryotes and cancer (1997) (13)
- Involvement in Meiotic Prophase of H1 Histone Kinase and p34cdc2 Homologues in Lily (Lilium longiflorum) Microsporocytes (1991) (13)
- The Spd1p S phase inhibitor can activate the DNA replication checkpoint pathway in fission yeast. (2000) (12)
- Mutational analysis of the fission yeast p34cdc2 protein kinase gene (2004) (12)
- The Wellcome Lecture, 1992. Cell cycle control. (1993) (12)
- The cdc18 protein initiates DNA replication in fission yeast. (1997) (12)
- Dependence of mitosis on DNA replication (1990) (11)
- Phosphorylation at Thr167 is required for Schizosaccharomyces pombe P34cdc2 function (1992) (11)
- An approach to identify functional homologues and suppressors of genes in fission yeast (1997) (11)
- CDK control pathways integrate cell size and ploidy information to control cell division (2021) (11)
- Identification of a Gl-type cyclin puc+ in the fission yeast Schizosaccharomyces pombe (1991) (10)
- Building Better Institutions (2013) (10)
- Phosphorylation of the RNA-binding protein Zfs1 modulates sexual differentiation in fission yeast (2017) (10)
- Core control principles of the eukaryotic cell cycle (2021) (10)
- The central role of a CDK in controlling the fission yeast cell cycle. (1996) (10)
- Using genetics to understand biology (2019) (10)
- Specific replication origins promote DNA amplification in fission yeast (2010) (9)
- 'Injecting' yeast (2009) (9)
- Screening and purification of natural products from actinomycetes that affect the cell shape of fission yeast (2017) (9)
- Oncogenes: Yeast aids cancer research (1985) (9)
- Expression of a dominant negative allele of cdc2 prevents activation of the endogenous p34cdc2 kinase (1991) (9)
- The Importance of Biology Education (2016) (8)
- Control over the onset of DNA synthesis in fission yeast. (1987) (8)
- Controlling S-phase onset in fission yeast. (2000) (8)
- Genetic interactions in the control of mitosis in fission yeast (1989) (7)
- Finding CDK: Linking yeast with humans (2012) (7)
- Cell cycle proteins (1996) (7)
- The Cdt 1 protein is required to license DNA for replication in ® ssion yeast (7)
- A Journey in Science: Cell-Cycle Control (2017) (7)
- Identification of mutants with increased variation in cell size at onset of mitosis in fission yeast (2021) (7)
- A Dominant Negative Allele of p 34 cdc 2 Shows Altered Phosphoamino Acid Content and Sequesters p 56 cdc Cyclin (1992) (7)
- A homeostatic mechanism rapidly corrects aberrant nucleocytoplasmic ratios maintaining nuclear size in fission yeast (2019) (7)
- Genetic analysis of human p34CDC2 function in fission yeast (1993) (6)
- The fission yeast cell cycle control gene cdc2: structure of the cdc2 region (1985) (6)
- Sorting out interphase microtubules (2007) (6)
- Emerging Themes in Biology: Hints for the Future (2014) (6)
- The EU: what's best for UK cancer research and patients? (2016) (6)
- Cell cycle control in the fission yeast Schizosaccharomyces pombe (the tenth fleming lecture) (1985) (6)
- Temperature sensitive allosuppressor mutants of the fission yeast S. pombe influence cell cycle control over mitosis (1984) (6)
- Genome-wide screen for cell growth regulators in fission yeast (2017) (6)
- corrigendum: The genome sequence of Schizosaccharomyces pombe (2003) (6)
- Evolutionary conservation of the human homologue of the yeast cell cycle control gene cdc2 and assignment of Cd2 to chromosome 10 (1988) (6)
- The controls acting at mitosis in Schizosaccharomyces pombe (1993) (6)
- 'Key regulators of the cell cycle': 2001 Nobel Prize for Physiology or Medicine (2001) (5)
- A quantitative and spatial analysis of cell cycle regulators during the fission yeast cycle (2022) (5)
- Transition probability and cell-cycle initiation in yeast (1977) (5)
- Fission yeast cell cycle mutants and the logic of eukaryotic cell cycle control. (2020) (5)
- Year : 2009 Cyclin-dependent kinase inhibits reinitiation of a normal S-phase program during G 2 in fission yeast (2010) (5)
- Cell divison: Coordinating histone transcription and DNA replication (1983) (5)
- Effects of genome position and the DNA damage checkpoint on the structure and frequency of sod2 gene amplification in fission yeast. (1999) (5)
- Mammalian Growth-Associated (1989) (5)
- Cyclin Dependent Kinases and Regulation of the Fission Yeast Cell Cycle (1999) (4)
- Checkpoint check (1993) (4)
- Yeast aids cancer research. (1985) (4)
- The dcd1-1-ts mutation in a fission yeast RCC1-like gene prevents chromosome decondensation at mitotic exit (1992) (3)
- Yoshio Masui and cell cycle control, past, present and future. (1998) (3)
- Corrigendum: Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe (2010) (3)
- Molecular biology of the fission yeast Edited by A. Nasim, P. Young, and B. F. Johnson. San Diego: Academic Press. (1989). 469 pp. $99.50 (1990) (3)
- The TOR‐dependent phosphoproteome and regulation of cellular protein synthesis (2021) (3)
- Screening and Purification of Natural Products from Actinomycetes that Induce a “Rounded” Morphological Phenotype in Fission Yeast (2021) (3)
- Cell cycle: bring on the phosphatases. (1993) (3)
- Analysis of 5' flanking sequences from the Schizosaccharomyces pombe cdc2 gene. (1993) (2)
- Genetic nomenclature guide. Schizosaccharomyces pombe. (1995) (2)
- Learning from the Uncontrollable (2016) (2)
- Analysis of Fission Yeast Single DNA Molecules on the Megabase Scale Using DNA Combing. (2018) (2)
- The genome sequence of Schizosaccharomyces pombe (vol 415, pg 871, 2002) (2003) (2)
- Coordinating histone transcription and DNA replication. (1983) (2)
- In answer to questions about the Francis Crick Institute (2012) (2)
- The potential consequences for cancer care and cancer research of Brexit (2017) (2)
- p 25 rum 1 promotes proteolysis of the mitotic B-cyclin p 56 cdc 13 during G 1 of the fission yeast cell cycle phosphorylation and action of a CKI . Two types of cyclin (2013) (2)
- On fission: The 1990 Marjory Stephenson Prize Lecture (1990) (2)
- Cancer research: joint planning for the future. (2003) (2)
- Identification of novel microtubule inhibitors effective in fission yeast and human cells and their effects on breast cancer cell lines (2021) (2)
- Cell-cycle control in yeasts [proceedings]. (1977) (2)
- REGULATORY GENES CONTROLLlNG MITOSIS I N THE FISSION YEAST SCHZZOSACCHAROMYCES POMBE (2003) (1)
- 644 The cell cycle, checkpoints, and cancer (1995) (1)
- The cell cycle. Preface. (2011) (1)
- Nobel microbes define the art of cell division. (2005) (1)
- Cell Cycle Control Genes of the Fission Yeast Schizosaccharomyces pombe (1986) (1)
- Towards a new phase in the cell cycle (1985) (1)
- 8 Cell Cycle Control in Fission Yeast (1997) (1)
- A CDK activity buffer ensures mitotic completion (2022) (1)
- Cell cycle. Checkpoints and spindles. (1991) (1)
- Imperial Cancer Research Fund and The Lancet (1997) (1)
- Cell cycle control genes of the unicellular eukaryote Schizosaccharomyces pombe (1983) (1)
- What determines cell size? (2012) (1)
- Felix Hoppe-Seyler Lecture 1999. Cyclin dependent kinases and regulation of the fission yeast cell cycle. (1999) (1)
- Cell Cycle Control (2000) (1)
- The great ideas of biology : the Romanes lecture for 2003 delivered before the University of Oxford on 30 October 2003 (2004) (1)
- The Imperial Cancer Research Fund—Cancer research for the future (1998) (1)
- Cell cycle regulation in yeasts and man: Towards a unifying mechanism (2004) (1)
- New concepts in (cid:142) ssion yeast morphogenesis (2003) (0)
- Correction: Screening and purification of natural products from actinomycetes that affect the cell shape of fission yeast (doi:10.1242/jcs.194571) (2018) (0)
- Genes controlling cell proliferation (1980) (0)
- Regulation of cell size at division in the fission yeastSchizosaccharomyces pombe (2005) (0)
- Controlling onset of S-phase (1996) (0)
- Microtubules mediate mitochondrial distribution in fission yeast ( cytoskeleton / Schizosaccharomyces pombe / organelle movement ) (2005) (0)
- VTC4: a regulator of vacuole size in fission yeast (2003) (0)
- Abstracts of papers presented at the 1987 Meeting on Yeast Cell Biology, August 11-August 16, 1987 (1987) (0)
- 2002genome sequence of Schizosaccharomyces pombe. V. Wood, R. Gwilliam, M -A. (2002) (0)
- Science on the Streets of the Big Apple (2008) (0)
- Synergistic CDK control pathways maintain cell size homeostasis (2020) (0)
- Eukaryotic chromosome replication : proceedings of a Royal Society discussion meeting held on 10 and 11 December 1986 (1987) (0)
- General Discussion .1. the Role of Protooncogenes in Amphibian Development (1990) (0)
- Identification of a small RhoA GTPase inhibitor effective in fission yeast and human cells (2023) (0)
- The cell cycle and cell size influence the rates of global cellular translation and transcription in fission yeast (2023) (0)
- Elements of the cell cycle (1996) (0)
- Author response for "Identification of novel microtubule inhibitors effective in fission yeast and human cells and their effects on breast cancer cell lines" (2021) (0)
- Core control principles of the eukaryotic cell cycle (2022) (0)
- Annotated Classic The Discovery of Cyclins (2014) (0)
- The Highly Civilized Man: Richard Burton and the Victorian World by Dane Kennedy, and; The Sad Story of Burton, Speke, and the Nile; or, Was John Hanning Speke a Cad? Looking at the Evidence by W. B. Carnochan (review) (2015) (0)
- Newsmaker interview. Nobelist Paul Nurse to pilot Royal Society, London superlab. Interview by Jocelyn Kaiser. (2010) (0)
- Jürg Bähler in Fission Yeast 2 during G Reinitiation of a Normal S-Phase Program Cyclin-Dependent Kinase Inhibits (2009) (0)
- Cell cycle regulation in fission yeast (1993) (0)
- The challenges in finding your home as a multidisciplinary scientist (2022) (0)
- Fission yeast pheromone blocks S-phase by inhibiting the G 1 cyclin B – p 34 cdc 2 kinase phosphorylation facilitates binding of FAR 1 to the CDK (2013) (0)
- IMPERIAL CANCER RESEARCH FUND AND THE LANCET. AUTHORS' REPLY (1997) (0)
- Model organism databases: essential resources that need the support of both funders and users (2016) (0)
- Ciba Medal Lecture. Eukaryotic cell-cycle control. (1992) (0)
- Author response: CDK control pathways integrate cell size and ploidy information to control cell division (2021) (0)
- DNA for replication in ® ssion yeast (0)
- Editorial Board (1995) (0)
- The Involvement of cdc2 in Cell Cycle Control of DNA Replication in Xenopus Egg Extracts (1992) (0)
- The Discovery of Cyclins (2015) (0)
- Rates of global cellular translation and transcription during cell growth and the cell cycle in fission yeast (2022) (0)
- Table of Contents (1995) (0)
- Editorial Board (1995) (0)
- General Discussion .2. Regulation of the Eukaryotic Cell-Cycle (1990) (0)
- A systematic screen reveals new elements acting at the G2/M cell cycle control (2012) (0)
- Nuclear membrane protein Lem2 regulates nuclear size through membrane flow (2019) (0)
- Eighth European Cell Cycle Workshop (1987) (0)
- Cell reproduction. (1987) (0)
- Editorial Board (1995) (0)
- Unravelling nuclear size control (2019) (0)
- EMBO at 50 (2014) (0)
- “Checkpoint Controls” in the cell cycle of Schizosaccharomyces pombe (1992) (0)
- Yoshio Masui and cell cycle control, past, present and future (1998) (0)
- Pegram Lectures: 'Controlling the Cell Cycle' and 'The Great Ideas of Biology' (2009) (0)
- Regulating S Phase: CDKs, Minireview Licensing and Proteolysis (1996) (0)
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