Paul Offit
#5,420
Most Influential Person
American immunologist
Why Is Paul Offit Influential?
(Suggest an Edit or Addition)According to Wikipedia, Paul Allan Offit is an American pediatrician specializing in infectious diseases, vaccines, immunology, and virology. He is the co-inventor of a rotavirus vaccine. Offit is the Maurice R. Hilleman Professor of Vaccinology, professor of pediatrics at the Perelman School of Medicine at the University of Pennsylvania, former chief of the Division of Infectious Diseases , and the director of the Vaccine Education Center at The Children's Hospital of Philadelphia. He has been a member of the Centers for Disease Control Advisory Committee on Immunization Practices. Offit is a board member of Every Child By Two and a Founding Board Member of the Autism Science Foundation .
Paul Offit's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Papers
- Safety and efficacy of a pentavalent human-bovine (WC3) reassortant rotavirus vaccine. (2006) (1611)
- Addressing parents' concerns: do multiple vaccines overwhelm or weaken the infant's immune system? (2002) (291)
- Vaccines and autism: a tale of shifting hypotheses. (2009) (290)
- Identification of the two rotavirus genes determining neutralization specificities (1986) (259)
- Rotavirus isolate WI61 representing a presumptive new human serotype (1987) (240)
- Molecular basis of rotavirus virulence: role of gene segment 4 (1986) (207)
- Passive protection against rotavirus-induced diarrhea by monoclonal antibodies to surface proteins vp3 and vp7 (1986) (201)
- Antigenic mapping of the surface proteins of rhesus rotavirus. (1986) (191)
- The development of multivalent bovine rotavirus (strain WC3) reassortant vaccine for infants. (1996) (189)
- Protection against rotavirus-induced gastroenteritis in a murine model by passively acquired gastrointestinal but not circulating antibodies (1985) (185)
- Reassortant rotaviruses containing structural proteins vp3 and vp7 from different parents induce antibodies protective against each parental serotype (1986) (171)
- SARS-CoV-2 Vaccines and the Growing Threat of Viral Variants. (2021) (157)
- Safety, efficacy, and immunogenicity of a live, quadrivalent human-bovine reassortant rotavirus vaccine in healthy infants. (2004) (155)
- Addressing parents' concerns: do vaccines contain harmful preservatives, adjuvants, additives, or residuals? (2003) (145)
- Use of Anthrax Vaccine in the United States: Recommendations of the Advisory Committee on Immunization Practices (2001) (131)
- Effects of the potency and composition of the multivalent human-bovine (WC3) reassortant rotavirus vaccine on efficacy, safety and immunogenicity in healthy infants. (2006) (121)
- Rotavirus-specific cytotoxic T lymphocytes appear at the intestinal mucosal surface after rotavirus infection (1989) (121)
- The Cutter incident, 50 years later. (2005) (108)
- Communicating science to the public: MMR vaccine and autism. (2003) (106)
- Yellow fever vaccine. Recommendations of the Advisory Committee on Immunization Practices (ACIP), 2002. (2002) (106)
- Plotkin's Vaccines (2017) (106)
- Identification of the simian rotavirus SA11 genome segment 3 product. (1988) (102)
- A murine model for oral infection with a primate rotavirus (simian SA11) (1984) (102)
- Passive protection against rotavirus-induced diarrhea by monoclonal antibodies to the heterotypic neutralization domain of VP7 and the VP8 fragment of VP4 (1989) (100)
- Development of a pentavalent rotavirus vaccine against prevalent serotypes of rotavirus gastroenteritis. (2005) (100)
- Immune response of infants and children to low-passage bovine rotavirus (strain WC3). (1986) (99)
- Vaccine Safety: Myths and Misinformation (2020) (99)
- Vaccine safety (1998) (96)
- Host factors associated with protection against rotavirus disease: the skies are clearing. (1996) (93)
- Addressing parents' concerns: do vaccines cause allergic or autoimmune diseases? (2003) (92)
- The Problem With Dr Bob's Alternative Vaccine Schedule (2009) (92)
- Rotavirus-specific cytotoxic T lymphocytes passively protect against gastroenteritis in suckling mice (1990) (87)
- Perspectives on the receipt of a COVID-19 vaccine: A survey of employees in two large hospitals in Philadelphia (2021) (86)
- Why are pharmaceutical companies gradually abandoning vaccines? (2005) (85)
- Rotavirus pathology and pathophysiology. (1994) (82)
- A randomized trial to increase acceptance of childhood vaccines by vaccine-hesitant parents: a pilot study. (2013) (80)
- Memory and distribution of virus-specific cytotoxic T lymphocytes (CTLs) and CTL precursors after rotavirus infection (1991) (73)
- Maternal antibody-mediated protection against gastroenteritis due to rotavirus in newborn mice is dependent on both serotype and titer of antibody. (1985) (72)
- Developing a SARS-CoV-2 Vaccine at Warp Speed. (2020) (68)
- Rotavirus-specific cytotoxic T lymphocytes cross-react with target cells infected with different rotavirus serotypes (1988) (66)
- Response of mice to rotaviruses of bovine or primate origin assessed by radioimmunoassay, radioimmunoprecipitation, and plaque reduction neutralization (1983) (65)
- Enhancement of rotavirus immunogenicity by microencapsulation. (1994) (64)
- Thimerosal and vaccines--a cautionary tale. (2007) (64)
- Safety, immunogenicity and efficacy in healthy infants of G1 and G2 human reassortant rotavirus vaccine in a new stabilizer/buffer liquid formulation (2003) (63)
- The New Pentavalent Rotavirus Vaccine Composed of Bovine (Strain WC3) -Human Rotavirus Reassortants (2006) (62)
- Vaccines and autism revisited--the Hannah Poling case. (2008) (62)
- Employee designation and health care worker support of an influenza vaccine mandate at a large pediatric tertiary care hospital. (2011) (61)
- Primary Murine Small Intestinal Epithelial Cells, Maintained in Long-Term Culture, Are Susceptible to Rotavirus Infection (2000) (59)
- Rotavirus-specific humoral and cellular immune response after primary, symptomatic infection. (1993) (58)
- VP4 genotyping of human rotavirus in the United States (1994) (58)
- Autism's False Prophets: Bad Science, Risky Medicine, and the Search for a Cure (2008) (55)
- Deadly Choices: How the Anti-Vaccine Movement Threatens Us All (2010) (55)
- Principal Controversies in Vaccine Safety in the United States. (2019) (54)
- Racial/Ethnic Differences in COVID-19 Vaccine Hesitancy Among Health Care Workers in 2 Large Academic Hospitals (2021) (52)
- Migration of antigen-presenting B cells from peripheral to mucosal lymphoid tissues may induce intestinal antigen-specific IgA following parenteral immunization. (1999) (52)
- Evaluation of the protective efficacy of a serotype 1 bovine-human rotavirus reassortant vaccine in infants. (1995) (51)
- The cultivation of human rotavirus, strain 'Wa', to high titer in cell culture and characterization of the viral structural polypeptides. (1983) (51)
- Rotaviruses: Immunological Determinants of Protection Against Infection and Disease (1994) (49)
- Rotavirus-specific proteins are detected in murine macrophages in both intestinal and extraintestinal lymphoid tissues. (1998) (48)
- Rotavirus immunoglobulin a responses stimulated by each of 3 doses of a quadrivalent human/bovine reassortant rotavirus vaccine. (2004) (46)
- Induction of virus-specific antibody production by lamina propria lymphocytes following intramuscular inoculation with rotavirus. (1995) (45)
- Outer capsid glycoprotein vp7 is recognized by cross-reactive, rotavirus-specific, cytotoxic T lymphocytes. (1991) (45)
- Circulating rotavirus-specific antibody-secreting cells (ASCs) predict the presence of rotavirus-specific ASCs in the human small intestinal lamina propria. (2000) (44)
- WC3 reassortant vaccines in children. (1996) (43)
- Vaccines for rotavirus gastroenteritis universally needed for infants. (2004) (43)
- Immunologic correlates of protection against rotavirus challenge after intramuscular immunization of mice (1997) (42)
- Rotavirus serotype-specific neutralizing activity in human milk. (1988) (39)
- Rotavirus-specific helper T cell responses in newborns, infants, children, and adults. (1992) (39)
- Oral inoculation of mice with low doses of microencapsulated, noninfectious rotavirus induces virus-specific antibodies in gut-associated lymphoid tissue. (1995) (38)
- B2 but Not B1 Cells Can Contribute to CD4+ T-Cell-Mediated Clearance of Rotavirus in SCID Mice (2001) (38)
- Hypertrophy, hyperplasia, and infectious virus in gut-associated lymphoid tissue of mice after oral inoculation with simian-human or bovine-human reassortant rotaviruses. (2001) (37)
- The meningococcal vaccine--public policy and individual choices. (2003) (35)
- Influence of potential protective mechanisms on the development of live rotavirus vaccines. (2010) (34)
- Noninfectious rotavirus (strain RRV) induces an immune response in mice which protects against rotavirus challenge (1989) (32)
- Gastroenteritis Caused By Human Rotaviruses (Serotype Three) In A Suckling Mouse Model* (1987) (31)
- Relative Importance of Rotavirus-Specific Effector and Memory B Cells in Protection against Challenge (1998) (31)
- The impact of access to immunization information on vaccine acceptance in three countries (2017) (30)
- Rotavirus-specific intestinal immune response in mice assessed by enzyme-linked immunospot assay and intestinal fragment culture. (1994) (29)
- The future of rotavirus vaccines. (2002) (26)
- Studying complementary and alternative therapies. (2012) (26)
- Addressing the Challenges of Serogroup B Meningococcal Disease Outbreaks on Campuses (2014) (26)
- Induction of rotavirus-specific cytotoxic T lymphocytes by vaccinia virus recombinants expressing individual rotavirus genes. (1994) (23)
- Ampicillin-Resistant, β-Lactamase-Negative Haemophilus influenzae Type b (1982) (22)
- RotaTeq: a pentavalent bovine--human reassortant rotavirus vaccine. (2006) (22)
- Vaccinated: One Man's Quest to Defeat the World's Deadliest Diseases (2007) (22)
- Response of adult human volunteers to oral administration of bovine and bovine/human reassortant rotaviruses. (1986) (22)
- Bad Faith: When Religious Belief Undermines Modern Medicine (2015) (22)
- Severe Epstein-Barr virus pulmonary involvement. (1981) (21)
- Do You Believe in Magic? The Sense and Nonsense of Alternative Medicine (2013) (21)
- COVID-19 vaccines for children. (2021) (21)
- Enhancement by microencapsulation of rotavirus-specific intestinal immune responses in mice assessed by enzyme-linked immunospot assay and intestinal fragment culture. (1995) (20)
- Correlates of protection against rotavirus infection and disease. (2008) (20)
- Presence of three P types (VP4 serotypes) and two G types (VP7 serotypes) among bovine rotavirus strains (2005) (20)
- Upper airway obstruction in association with perinatally acquired herpes simplex virus infection. (1992) (19)
- Polypeptide specificity of antiviral serum antibodies in children naturally infected with human rotavirus (1990) (19)
- Induction of Mucosal B-Cell Memory by Intramuscular Inoculation of Mice with Rotavirus (1998) (19)
- Infant immune response to human rotavirus serotype G1 vaccine candidate reassortant WI79-9: different dose response patterns to virus surface proteins VP7 and VP4 (2004) (19)
- The development of COVID-19 vaccines in the United States: Why and how so fast? (2021) (19)
- Neutralizing antibodies to heterologous animal rotavirus serotypes 5, 6, 7, and 10 in sera from Ecuadorian children (1991) (18)
- Evaluation of a bovine-human rotavirus reassortant vaccine in infants. (1993) (18)
- Immunologic determinants of protection against rotavirus disease. (1994) (18)
- Aqueous-based microencapsulation enhances virus-specific humoral immune responses in mice after parenteral inoculation. (1996) (17)
- Bad Advice: Or Why Celebrities, Politicians, and Activists Aren't Your Best Source of Health Information (2018) (17)
- Effect of Water-Based Microencapsulation on Protection against EDIM Rotavirus Challenge in Mice (1998) (16)
- Distribution of rotavirus-specific memory B cells in gut-associated lymphoid tissue after primary immunization. (2001) (15)
- The science of vaccine safety: Summary of meeting at Wellcome Trust. (2020) (13)
- Rotavirus-specific cytotoxic T lymphocyte response of mice after oral inoculation with candidate rotavirus vaccine strains RRV or WC3. (1989) (13)
- Effect of microencapsulation on immunogenicity of a bovine herpes virus glycoprotein and inactivated influenza virus in mice. (1997) (13)
- On the Shoulders of Giants - From Jenner's Cowpox to mRNA Covid Vaccines. (2021) (12)
- Bad Advice (2018) (12)
- Adjuvants, Additives, or Residuals? Addressing Parents' Concerns: Do Vaccines Contain Harmful Preservatives, (2005) (11)
- Unusual presentation of group B Streptococcus osteomyelitis. (1992) (11)
- Vaccines Against Human Hookworm Disease (2004) (10)
- Covid-19 Boosters — Where from Here? (2022) (10)
- Treatment With Quadrivalent Human Papillomavirus Vaccine for Juvenile-Onset Recurrent Respiratory Papillomatosis: Case Report and Review of the Literature (2017) (10)
- Vaccines and Your Child: Separating Fact from Fiction (2011) (10)
- Coronavirus disease 2019 (COVID-19) vaccine hesitancy among physicians, physician assistants, nurse practitioners, and nurses in two academic hospitals in Philadelphia (2021) (10)
- 25 – Development of a Mucosal Rotavirus Vaccine (1996) (10)
- Preventing harm from thimerosal in vaccines. (2000) (9)
- Should childhood vaccination be mandatory? Yes (2012) (9)
- The power of ‘box a’ (2003) (9)
- Challenges to Developing a Rotavirus Vaccine. (2017) (9)
- New vaccines against mucosal pathogens: rotavirus and respiratory syncytial virus. (1997) (8)
- Ampicillin-resistant, beta-lactamase-negative haemophilus influenzae type b. (1982) (8)
- Acyclovir therapy in neonatal herpes simplex virus infection. (1982) (8)
- II, 13. Current state of development of human rotavirus vaccines (2003) (8)
- Tactile Defensiveness and Discrimination Test-Revised (2021) (8)
- Meningococcal conjugate vaccine in the UK: an update (2004) (7)
- Delaying vaccination is not a safer choice. (2013) (7)
- Rotavirus-specific antibodies in fetal bovine serum and commercial preparations of serum albumin (1984) (7)
- Incomplete financial disclosure in a viewpoint on complementary and alternative therapies. (2012) (7)
- Comprar Vaccines, 5th Edition: Expert Consult | Paul A. Offit | 9781416036111 | Saunders (2008) (7)
- Preventing harm from thimerosal in vaccines [3] (multiple letter) (2000) (6)
- 30 – Rotavirus vaccines (2013) (6)
- A quantitative luminescence assay for measuring cell uptake of aqueous-based microcapsules in vitro. (2000) (6)
- Japanese physicians’ attitudes and intentions regarding human papillomavirus vaccine compared with other adolescent vaccines (2019) (6)
- Rotavirus-specific protein synthesis is not necessary for recognition of infected cells by virus-specific cytotoxic T lymphocytes (1989) (6)
- Vaccines and Autism (2002) (5)
- Communicating vaccine science to the public. (2014) (4)
- Vaccines and autism in primate model (2015) (4)
- How vaccine safety is monitored before and after licensure. (2001) (4)
- Relative Importance of Rotavirus-Specific Effector and Memory B Cells in Protection against Challenge (1998) (4)
- The Vaccine Schedule (2011) (3)
- 1076 ROTAVIRUSES (RV) OF BOVINE AND HUMAN ORIGIN: IMMUNE RESPONSE OF ADUIITS AND CHILDREN FOLLOWING ORAL ADMINISTRATION (1985) (3)
- The Anti-Vax Movement and What Allergists Can Do. (2020) (3)
- Specific attachment of aqueous-based microcapsules to macrophages, B cells, and dendritic cells in vitro (2002) (3)
- Improving vaccine policy making: A dose of reality. (2020) (3)
- Implementation of a Mandatory Influenza Vaccine Policy: A 10-Year Experience. (2020) (3)
- Thimerosal and autism (2004) (3)
- Viral diseases: infections of the gastrointestinal tract. (1982) (3)
- Vaccine Safety (2017) (3)
- New Book About Vaccine Safety (2008) (3)
- Determination of efficiency of attachment of biotinylated antibodies to avidin-linked, aqueous-based microcapsules by flow cytometry. (2003) (2)
- Rotavirus vaccine (1999) (2)
- Could fever improve COVID-19 outcomes? (2020) (2)
- Comparison of immunization systems in Japan and the United States - What can be learned? (2020) (2)
- Vaccine mandates in France will save lives (2018) (2)
- 52 – Rotavirus Vaccines (2018) (2)
- Rotavirus Vaccines: Round Two (2006) (2)
- A statement regarding personal belief exemption from immunization mandates: from the Pediatric Infectious Diseases Society, March 2011. (2011) (2)
- Rotavirus vaccine (1998) (2)
- Why Aren't International Travelers Vaccinated for Measles? (2017) (1)
- Motion picture sickness (2016) (1)
- Rotavirus Vaccines Part II: Raising the Bar for Vaccine Safety Studies (2011) (1)
- Preface to the Seventh Edition (2018) (1)
- Do You Believe in Magic (2013) (1)
- Polio revisited Gareth Williams Paralysed with Fear: the (2013) (1)
- Viral Microencapsulation Delays Protection after Intramuscular Inoculation of Mice with Rotavirus (1999) (1)
- Immunologic methods and correlates of protection. (2000) (1)
- Important New Resource for Clinicians Giving Expert Witness Testimony on Vaccines. (2018) (1)
- Diseases? Addressing Parents' Concerns: Do Vaccines Cause Allergic or Autoimmune (2005) (1)
- Vaccinations and Autism (2021) (1)
- Don’t Hesitate – Vaccinate! (2020) (1)
- Too many vaccinations ? Authors' reply (2002) (1)
- Celebrating the Centennial of the Birth of the World's Greatest Vaccinologist, Maurice R. Hilleman, 1919-2005. (2020) (0)
- Following Parenteral Immunization May Induce Intestinal Antigen-Specific IgA Peripheral to Mucosal Lymphoid Tissues Migration of Antigen-Presenting B Cells from (1999) (0)
- Complementary Health Practices—Reply (2012) (0)
- Intestinal virus-specific IgA production following IM immunization is induced by non-immune, antigen-presenting B cells. (1999) (0)
- Understanding the Anti-Vaccine Movement (2009) (0)
- 3. The Implosion (2008) (0)
- Don't Force Parents to Vaccinate Their Kids. Incentivize Them to Do It (2020) (0)
- Flawed research and its enduring repercussions (2020) (0)
- Thiothixene Hydrochloride (2020) (0)
- Compassionate Use for Public Health (2014) (0)
- Back to the future (2004) (0)
- Calming a Parent's Vaccine Fears (2016) (0)
- a VaccineEducationCenter,Children'sHospitalofPhiladelphia,Philadelphia,Pennsylvania; b DepartmentofPediatrics,SchoolofMedicine,UniversityofPennsylvania, (2009) (0)
- 5. Mercury Rising (2008) (0)
- 9. Science and the Media (2008) (0)
- Vaccines: An Educational Imperative & Opportunity for Biology Teachers (2019) (0)
- Vaccines in the Second Year of Life (2011) (0)
- Pertussis and Autism (2021) (0)
- Communicating with Health Care Professionals (2009) (0)
- Perception of Japanese Physicians about Human Papillomavirus Vaccine (2017) (0)
- Maintaining the public's trust in immunizations. (2000) (0)
- 7. Behind the Mercury Curtain (2008) (0)
- Liaisons from Organizations (2010) (0)
- Immunization Symposium (2020) (0)
- Killing Us Softly (2013) (0)
- Vaccines in the First Year of Life (2011) (0)
- 4. A Precautionary Tale (2008) (0)
- Book Review: Rejoinder from the author (2014) (0)
- Vaccine safety (2008) (0)
- 110 Hard Knocks: Communicating Science to the Public (2012) (0)
- The Vaccine-Autism Controversy (2017) (0)
- In vitro production of rotavirus specific immuno globulin a after oral immunization of humans (1984) (0)
- 10. Science and Society (2008) (0)
- Rotavirus Infection of Cultured Primary Murine Small Intestinal Epithelial Cells 874 (1998) (0)
- Preface to the fifth edition (2008) (0)
- Status of rubella vaccines (1981) (0)
- Epilogue: “Next, on Oprah” (2008) (0)
- Vaccination Has Eliminated Infectious Diseases at the Price of Causing Chronic Diseases (2008) (0)
- Vaccines, Calling the Shots (2014) (0)
- "Stay the Course: Science, Prevention, Education, Training, Evaluation & Update!" (2016) (0)
- Subunitary vaccine encapsulation against virus of bovine herpes type 1 based on a water solvent. (1998) (0)
- Contributors (2008) (0)
- Measles Virus RNA and Autism Revisited (2004) (0)
- Recombinant vaccine rotavirus. (1991) (0)
- CIRCULATING ROTAVIRUS-SPECIFIC ANTIBODY-SECRETING CELLS (ASCs) ARE A PREDICTOR OF ASCs IN THE HUMAN SMALL INTESTINE LAMINA PROPRIA (1999) (0)
- 8. Science in Court (2008) (0)
- Combating 'Vaccine Hesitancy,' Northwest Health Initiative Reports Gains (2020) (0)
- The “ Wakefield ” Studies : Studies Hypothesizing That MMR Causes Autism (2005) (0)
- Vaccines Against Rotavirus Gastroenteritis (2016) (0)
- Ethical considerations in the vaccine life cycle : an overview (2013) (0)
- Vaccines handbook : mobile version : a companion to Plotkin, Orenstein's and Offit's Vaccines (2009) (0)
- Preface to the sixth edition (2013) (0)
- The Cutter Incident (2017) (0)
- 6. Mercury Falling (2008) (0)
- Measles and Autism (2021) (0)
- 2. Lighting the Fuse (2008) (0)
- against Challenge Effector and Memory B Cells in Protection Relative Importance of Rotavirus-Specific (2013) (0)
- 11. A Place for Autism (2008) (0)
- Vaccines for Adolescents and Teens (2011) (0)
- 659A comparison of local determinants of vaccine hesitancy in Botswana and the Dominican Republic, two middle-income countries (2014) (0)
- Chapter 1. Little White Coffins (2017) (0)
- Measles-Mumps-Rubella (MMR) Vaccination (2021) (0)
- Vaccine Exemptions: When Do Individual Rights Trump Societal Good? (2015) (0)
- 1. The Tinderbox (2008) (0)
- Chapter 9. Death for the Lambs (2017) (0)
- 5 Things We Know to Be True. (2016) (0)
- In Memoriam (2012) (0)
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What Schools Are Affiliated With Paul Offit?
Paul Offit is affiliated with the following schools:
