Paul Wender
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American chemist
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Chemistry
Paul Wender's Degrees
- PhD Chemistry University of California, Berkeley
- Bachelors Chemistry University of California, Berkeley
Why Is Paul Wender Influential?
(Suggest an Edit or Addition)According to Wikipedia, Paul A. Wender is an American chemist whose work is focused on organic chemistry, organometallic chemistry, synthesis, catalysis, chemical biology, imaging, drug delivery, and molecular therapeutics. He is currently the Francis W. Bergstrom Professor of Chemistry at Stanford University and is an Elected Fellow at the American Association for the Advancement of Science and the American Academy of Arts and Sciences.
Paul Wender's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: peptoid molecular transporters. (2000) (1447)
- Nanotube molecular transporters: internalization of carbon nanotube-protein conjugates into Mammalian cells. (2004) (1241)
- Function-oriented synthesis, step economy, and drug design. (2008) (829)
- Conjugation of arginine oligomers to cyclosporin A facilitates topical delivery and inhibition of inflammation (2000) (588)
- Role of membrane potential and hydrogen bonding in the mechanism of translocation of guanidinium-rich peptides into cells. (2004) (538)
- Synthesis at the molecular frontier (2009) (399)
- The design of guanidinium-rich transporters and their internalization mechanisms. (2008) (384)
- Taxol®: science and applications. (1995) (361)
- Arginine-rich molecular transporters for drug delivery: role of backbone spacing in cellular uptake. (2002) (287)
- Retrosynthetic Reaction Prediction Using Neural Sequence-to-Sequence Models (2017) (283)
- Adaptive translocation: the role of hydrogen bonding and membrane potential in the uptake of guanidinium-rich transporters into cells. (2005) (276)
- Transition Metal Catalyzed [5 + 2] Cycloadditions of Vinylcyclopropanes and Alkynes: A Homolog of the Diels-Alder Reaction for the Synthesis of Seven-Membered Rings (1995) (250)
- Fifteen years of cell-penetrating, guanidinium-rich molecular transporters: basic science, research tools, and clinical applications. (2013) (249)
- Overcoming multidrug resistance of small-molecule therapeutics through conjugation with releasable octaarginine transporters (2008) (219)
- The Pinene Path to Taxanes. 6. A Concise Stereocontrolled Synthesis of Taxol (1997) (193)
- Practical Synthesis of Prostratin, DPP, and Their Analogs, Adjuvant Leads Against Latent HIV (2008) (170)
- Modeling of the bryostatins to the phorbol ester pharmacophore on protein kinase C. (1988) (156)
- Molecular transporters for peptides: delivery of a cardioprotective epsilonPKC agonist peptide into cells and intact ischemic heart using a transport system, R(7). (2001) (153)
- New reactions and step economy: the total synthesis of (±)-salsolene oxide based on the type II transition metal-catalyzed intramolecular [4 + 4] cycloaddition (2006) (153)
- Designed, Synthetically Accessible Bryostatin Analogues Potently Induce Activation of Latent HIV Reservoirs in vitro (2012) (151)
- Charge-altering releasable transporters (CARTs) for the delivery and release of mRNA in living animals (2017) (150)
- Oligocarbamate molecular transporters: design, synthesis, and biological evaluation of a new class of transporters for drug delivery. (2002) (149)
- A computationally designed Rh(I)-catalyzed two-component [5+2+1] cycloaddition of ene-vinylcyclopropanes and CO for the synthesis of cyclooctenones. (2007) (144)
- The First Synthesis of a Daphnane Diterpene: The Enantiocontrolled Total Synthesis of (+)-Resiniferatoxin (1997) (144)
- The First Formal Asymmetric Synthesis of Phorbol (1997) (141)
- The practical synthesis of a novel and highly potent analogue of bryostatin. (2002) (139)
- Releasable luciferin-transporter conjugates: tools for the real-time analysis of cellular uptake and release. (2006) (138)
- Molecular Transporters: Synthesis of Oligoguanidinium Transporters and Their Application to Drug Delivery and Real‐Time Imaging (2006) (137)
- Toward the ideal synthesis and molecular function through synthesis-informed design. (2014) (135)
- On the mechanism of [Rh(CO)2Cl]2-catalyzed intermolecular (5 + 2) reactions between vinylcyclopropanes and alkynes. (2004) (133)
- Asymmetric catalysis of the [5 + 2] cycloaddition reaction of vinylcyclopropanes and pi-systems. (2006) (128)
- Studies on tumor promoters. 9. A second-generation synthesis of phorbol (1990) (127)
- A new and practical approach to the synthesis of taxol and taxol analogs: the pinene path. (1992) (126)
- The Pinene Path to Taxanes. 5. Stereocontrolled Synthesis of a Versatile Taxane Precursor (1997) (124)
- Analysis of the phorbol ester pharmacophore on protein kinase C as a guide to the rational design of new classes of analogs. (1986) (123)
- Enhanced mRNA delivery into lymphocytes enabled by lipid-varied libraries of charge-altering releasable transporters (2018) (122)
- Highly potent, synthetically accessible prostratin analogs induce latent HIV expression in vitro and ex vivo (2013) (121)
- Molecular Basis for Protein Kinase C Isozyme-Selective Binding: The Synthesis, Folding, and Phorbol Ester Binding of the Cysteine-Rich Domains of All Protein Kinase C Isozymes (1998) (120)
- Origins of differences in reactivities of alkenes, alkynes, and allenes in [Rh(CO)2Cl]2-catalyzed (5 + 2) cycloaddition reactions with vinylcyclopropanes. (2008) (119)
- Transition metal-catalyzed hetero-[5 + 2] cycloadditions of cyclopropyl imines and alkynes: dihydroazepines from simple, readily available starting materials. (2002) (118)
- Introduction: Frontiers in Organic Synthesis. (1996) (118)
- Transition metal-catalyzed intermolecular [5+2] and [5+2+1] cycloadditions of allenes and vinylcyclopropanes. (2005) (116)
- Multicomponent cycloadditions: the four-component [5+1+2+1] cycloaddition of vinylcyclopropanes, alkynes, and CO. (2005) (116)
- First Studies of the Transition Metal‐Catalyzed [5+2] Cycloadditions of Alkenes and Vinylcyclopropanes: Scope and Stereochemistry. (1998) (114)
- Efficient synthetic access to a new family of highly potent bryostatin analogues via a Prins-driven macrocyclization strategy. (2008) (114)
- Cyclopentadienone synthesis by rhodium(I)-catalyzed [3 + 2] cycloaddition reactions of cyclopropenones and alkynes. (2006) (108)
- Three-component cycloadditions: the first transition metal-catalyzed [5+2+1] cycloaddition reactions. (2002) (108)
- Transition Metal-Catalyzed (6+2) Cycloadditions of 2-Vinylcyclobutanones and Alkenes: A New Reaction for the Synthesis of Eight-Membered Rings (2000) (107)
- Oligocarbonate molecular transporters: oligomerization-based syntheses and cell-penetrating studies. (2009) (106)
- Cyclocarboamination of alkynes with aziridines: synthesis of 2,3-dihydropyrroles by a catalyzed formal [3 + 2] cycloaddition. (2009) (105)
- Electronic and steric control of regioselectivities in Rh(I)-catalyzed (5 + 2) cycloadditions: experiment and theory. (2010) (105)
- The first intermolecular transition metal-catalyzed [5+2] cycloadditions with simple, unactivated, vinylcyclopropanes. (2001) (103)
- Transition Metal-Catalyzed Intramolecular [4 + 2] Diene-Allene Cycloadditions: A Convenient Synthesis of Angularly Substituted Ring Systems with Provision for Catalyst-Controlled Chemo- and Stereocomplementarity (1995) (103)
- Designed guanidinium-rich amphipathic oligocarbonate molecular transporters complex, deliver and release siRNA in cells (2012) (102)
- Total synthesis of bryostatin 9. (2011) (102)
- Studies on tumor promoters. 7. The synthesis of a potentially general precursor of the tiglianes, daphnanes, and ingenanes (1989) (101)
- Nickel-catalyzed intramolecular [4+4] cycloadditions. 4. Enantioselective total synthesis of (+)-asteriscanolide (1988) (101)
- Toward the ideal synthesis. New transition metal-catalyzed reactions inspired by novel medicinal leads (2002) (101)
- Molecular dynamics simulations reveal ligand-controlled positioning of a peripheral protein complex in membranes (2017) (99)
- Transition Metal-Catalyzed [5 + 2] Cycloadditions of Allenes and Vinylcyclopropanes: First Studies of Endo−Exo Selectivity, Chemoselectivity, Relative Stereochemistry, and Chirality Transfer (1999) (99)
- Nickel-catalyzed intramolecular [4 + 4]-cycloadditions: a new method for the synthesis of polycycles containing eight-membered rings (1986) (98)
- STUDIES ON TUMOR PROMOTERS .8. THE SYNTHESIS OF PHORBOL (1989) (97)
- Synthesis of the First Members of a New Class of Biologically Active Bryostatin Analogues (1998) (97)
- Effect of histone deacetylase inhibitors on HIV production in latently infected, resting CD4(+) T cells from infected individuals receiving effective antiretroviral therapy. (2012) (97)
- Ligand effects on rates and regioselectivities of Rh(I)-catalyzed (5 + 2) cycloadditions: a computational study of cyclooctadiene and dinaphthocyclooctatetraene as ligands. (2012) (97)
- The Transition Metal-Catalyzed Intermolecular [5+2] Cycloaddition: The Homologous Diels−Alder Reaction (1998) (95)
- [(arene)Rh(cod)]+ Complexes as catalysts for [5+2] cycloaddition reactions. (2002) (93)
- Design, synthesis, and evaluation of potent bryostatin analogs that modulate PKC translocation selectivity (2011) (93)
- The design, computer modeling, solution structure, and biological evaluation of synthetic analogs of bryostatin 1. (1998) (92)
- Total synthesis of (-)-laulimalide. (2000) (92)
- Cell-Penetrating, Guanidinium-Rich Oligophosphoesters: Effective and Versatile Molecular Transporters for Drug and Probe Delivery. (2016) (88)
- A metal-catalyzed intermolecular [5+2] cycloaddition/Nazarov cyclization sequence and cascade. (2010) (87)
- Substituent effects, reactant preorganization, and ligand exchange control the reactivity in Rh(I)-catalyzed (5+2) cycloadditions between vinylcyclopropanes and alkynes. (2008) (84)
- Nickel-catalyzed intramolecular [4+2] dienyne cycloadditions: an efficient new method for the synthesis of polycycles containing cyclohexa-1,4-dienes (1989) (83)
- Toward the Ideal Synthesis and Transformative Therapies: The Roles of Step Economy and Function Oriented Synthesis. (2013) (83)
- Rhodium-Catalyzed [5 + 2] Cycloadditions of Allenes and Vinylcyclopropanes: Asymmetric Total Synthesis of (+)-Dictamnol. (1999) (82)
- General methodology for the synthesis of neocarzinostatin chromophore analogues : intramolecular chromium-mediated closures for strained-ring synthesis (1990) (82)
- A Dual-Function Antibiotic-Transporter Conjugate Exhibits Superior Activity in Sterilizing MRSA Biofilms and Killing Persister Cells. (2018) (81)
- Late-stage intermolecular CH activation for lead diversification: a highly chemoselective oxyfunctionalization of the C-9 position of potent bryostatin analogues. (2005) (81)
- Real-time analysis of uptake and bioactivatable cleavage of luciferin-transporter conjugates in transgenic reporter mice (2007) (77)
- Guanidinium rich peptide transporters and drug delivery. (2003) (75)
- Intracellular cargo delivery by an octaarginine transporter adapted to target prostate cancer cells through cell surface protease activation. (2006) (74)
- Reactivity and Chemoselectivity of Allenes in Rh(I)-Catalyzed Intermolecular (5 + 2) Cycloadditions with Vinylcyclopropanes: Allene-Mediated Rhodacycle Formation Can Poison Rh(I)-Catalyzed Cycloadditions (2014) (74)
- Transition Metal-Catalyzed [5+2] Cycloadditions with Substituted Cyclopropanes: First Studies of Regio- and Stereoselectivity (1999) (72)
- Synthetic studies on arene-olefin cycloadditions: total synthesis of (.+-.)-.alpha.-cedrene (1981) (72)
- Arginine-based molecular transporters: the synthesis and chemical evaluation of releasable taxol-transporter conjugates. (2003) (71)
- A New and Selective Catalyst for the [5 + 2] Cycloaddition of Vinylcyclopropanes and Alkynes (1998) (71)
- Studies on tumor promoters. 11. A new [5+2] cycloaddition method and its application to the synthesis of BC ring precursors of phorboids (1991) (70)
- Cellular delivery and photochemical release of a caged inositol-pyrophosphate induces PH-domain translocation in cellulo (2016) (70)
- mRNA vaccination with charge-altering releasable transporters elicits human T cell responses and cures established tumors in mice (2018) (70)
- Gene transfer via reversible plasmid condensation with cysteine-flanked, internally spaced arginine-rich peptides. (2003) (69)
- Toward the identification of selective modulators of protein kinase C (PKC) isozymes: establishment of a binding assay for PKC isozymes using synthetic C1 peptide receptors and identification of the critical residues involved in the phorbol ester binding. (2001) (69)
- Studies on DNA - active agents: The synthesis of the parent carbocyclic subunit of neocarzinostatin chromophore A (1988) (69)
- In vivo activation of latent HIV with a synthetic bryostatin analog effects both latent cell "kick" and "kill" in strategy for virus eradication (2017) (69)
- Scalable synthesis of bryostatin 1 and analogs, adjuvant leads against latent HIV (2017) (68)
- Synthetic studies on arene-olefin cycloadditions. 4. Total synthesis of (.+-.)-modhephene (1982) (68)
- Delivery of antimicrobials into parasites (2003) (68)
- Actin is the primary cellular receptor of bistramide A (2005) (67)
- The rational design of potential chemotherapeutic agents: Synthesis of bryostatin analogues (1999) (67)
- Asymmetric synthesis of the tricyclic core of NGF-inducing cyathane diterpenes via a transition-metal-catalyzed [5 + 2] cycloaddition. (2001) (66)
- The first metal-catalyzed intramolecular [5+2] cycloadditions of vinylcyclopropanes and alkenes: Scope, stereochemistry, and asymmetric catalysis (1998) (64)
- Synthetic studies on arene-olefin cycloadditions. ii. total synthesis of (±)-isocomene (1981) (62)
- A cellular model of Alzheimer's disease therapeutic efficacy: PKC activation reverses Aβ-induced biomarker abnormality on cultured fibroblasts (2009) (62)
- RhI-catalyzed C-C bond activation: seven-membered ring synthesis by a [6+1] carbonylative ring-expansion reaction of allenylcyclobutanes. (2006) (61)
- Asymmetric total synthesis of (+)-aphanamol I based on the transition metal catalyzed [5 + 2] cycloaddition of allenes and vinylcyclopropanes. (2000) (61)
- Transition Metal Catalyzed Cycloadditions: An Intramolecular [4 + 4] Cycloaddition Strategy for the Efficient Synthesis of Dicyclopenta[a,d]cyclooctene 5−8−5 Ring Systems (1997) (61)
- Gateway synthesis of daphnane congeners and their protein kinase C affinities and cell-growth activities. (2011) (60)
- Microtubule-stabilizing agents based on designed laulimalide analogues. (2004) (59)
- Arene-alkene cycloadditions and organic synthesis (1990) (59)
- Local Delivery of Ox40l, Cd80, and Cd86 mRNA Kindles Global Anticancer Immunity. (2019) (59)
- Dendrimeric molecular transporters: synthesis and evaluation of tunable polyguanidino dendrimers that facilitate cellular uptake. (2005) (58)
- Intramolecular nickel catalyzed cycloadditions of bis-dienes: 3 approaches to the taxane skeleton☆ (1987) (58)
- An approach to the site-selective diversification of apoptolidin A with peptide-based catalysts. (2009) (58)
- Rhodium dinaphthocyclooctatetraene complexes: synthesis, characterization and catalytic activity in [5+2] cycloadditions. (2012) (55)
- Studies on DNA-cleaving agents: synthesis of a functional dynemicin analogue (1991) (55)
- Reaction of allylically substituted enolates with organometallic reagents: a convenient source of enolonium ion equivalents (1981) (55)
- Function through Synthesis-Informed Design (2015) (54)
- A photochemically triggered DNA cleaving agent: synthesis, mechanistic and DNA cleavage studies on a new analog of the anti-tumor antibiotic dynemicin (1993) (53)
- Synthetic studies on arene-olepin cycloadditions-VII:1 a three-step total synthesis of (±)-silphinene (1985) (53)
- Metal-catalyzed [2+2+1] cycloadditions of 1,3-dienes, allenes, and CO. (2006) (52)
- Single-molecule motions of oligoarginine transporter conjugates on the plasma membrane of Chinese hamster ovary cells. (2008) (51)
- Bioengineered Vaults: Self-Assembling Protein Shell–Lipophilic Core Nanoparticles for Drug Delivery (2014) (51)
- Preparation and cycloadditions of a 4-methoxy-3-oxidopyrylium ylid: a reagent for the synthesis of highly substituted seven-membered rings and tetrahydrofurans (1992) (51)
- Structural Complexity Through Multicomponent Cycloaddition Cascades Enabled by Dual-Purpose, Reactivity Regenerating 1,2,3-Triene Equivalents (2014) (51)
- A general methodology for pseudoguaiane synthesis: total synthesis of (.+-.)-damsinic acid and (.+-.)-confertin (1979) (51)
- Nickel(0)-catalyzed [2 + 2 + 2 + 2] cycloadditions of terminal diynes for the synthesis of substituted cyclooctatetraenes. (2007) (51)
- Nickel-catalyzed intramolecular [4+4] cycloadditions: 2. Allylic stereoinduction and modelling studies in the preparation of bicyclo[6.4.0]dodecadienes (1987) (50)
- Macroexpansion methodology : Medium ring synthesis based on an eight unit ring expansion process (1981) (50)
- A proapoptotic signaling pathway involving RasGRP, Erk, and Bim in B cells. (2009) (50)
- The design, synthesis, and evaluation of C7 diversified bryostatin analogs reveals a hot spot for PKC affinity. (2008) (49)
- Synthetic studies on arene-olefin cycloadditions. 11. Total synthesis of (−)-retigeranic acid (1990) (48)
- Cell-Penetrating, Guanidinium-Rich Molecular Transporters for Overcoming Efflux-Mediated Multidrug Resistance (2014) (48)
- Rhodium(I)-catalyzed [2+2+1] cycloadditions of 1,3-dienes, alkenes, and CO. (2004) (48)
- Synthesis and biological evaluation of (-)-laulimalide analogues. (2003) (47)
- Transition Metal-Catalyzed Intramolecular [4 + 2] Cycloadditions: A Novel Method for the Assembly of Nitrogen Heterocycles and Its Application to Yohimban Alkaloid Synthesis (1996) (46)
- An efficient, scalable synthesis of the molecular transporter octaarginine via a segment doubling strategy. (2001) (46)
- Function oriented synthesis: the design, synthesis, PKC binding and translocation activity of a new bryostatin analog. (2004) (46)
- Macroexpansion methodology. 3. Eight-step synthesis of (-)-(3Z)-cembrene A (1985) (46)
- The photochemistry of 1-alkenylbenzotriazoles : Methodology for the synthesis of indoles (1986) (44)
- Translating Nature's Library: The Bryostatins and Function-Oriented Synthesis. (2011) (44)
- The synthesis of highly substituted cyclooctatetraene scaffolds by metal-catalyzed [2+2+2+2] cycloadditions: studies on regioselectivity, dynamic properties, and metal chelation. (2009) (44)
- The Diene Effect: The Design, Development, and Mechanistic Investigation of Metal-Catalyzed Diene-yne, Diene-ene, and Diene-allene [2+2+1] Cycloaddition Reactions (2010) (44)
- A molecular method for the delivery of small molecules and proteins across the cell wall of algae using molecular transporters (2012) (44)
- Transition metal-catalyzed intramolecular [4 + 2] cycloadditions: Mechanistic and synthetic investigations (1998) (44)
- Synthetic studies on arene-olefin cycloadditions. 10. A concise, stereocontrolled total synthesis of (.+-.)-laurenene (1988) (44)
- Laulimalide and synthetic laulimalide analogues are synergistic with paclitaxel and 2-methoxyestradiol. (2006) (44)
- Practical method for .alpha.-alkenyl ketone synthesis based on a facile reductive rearrangement of alkynyl halohydrins (1983) (44)
- Intermolecular dienyl Pauson-Khand reaction. (2004) (44)
- Rhodium(I)-catalyzed [4+2+2] cycloadditions of 1,3-dienes, alkenes, and alkynes for the synthesis of cyclooctadienes. (2006) (44)
- Studies on oxidopyrylium [5+2] cycloadditions: toward a general synthetic route to the C12-hydroxydaphnetoxins. (2006) (44)
- Bioorthogonal Catalysis: A General Method To Evaluate Metal-Catalyzed Reactions in Real Time in Living Systems Using a Cellular Luciferase Reporter System (2015) (43)
- METHODOLOGY FOR THE FACILE AND REGIO-CONTROLLED SYNTHESIS OF INDOLES (1983) (43)
- The dienyl Pauson-Khand reaction. (2003) (43)
- Oligo(serine ester) Charge-Altering Releasable Transporters: Organocatalytic Ring-Opening Polymerization and their Use for in Vitro and in Vivo mRNA Delivery. (2019) (42)
- A Vancomycin-Arginine Conjugate Inhibits Growth of Carbapenem-resistant E. coli and Targets Cell-Wall Synthesis. (2019) (42)
- Synthetic studies on arene-olefin cycloadditions -III- total synthesis of (±)-hirsutene☆ (1982) (41)
- Stereochemistry of dialkylcuprate additions to cyclopropyl acrylic esters. An application to the synthesis of (.+-.)-eremophilone (1977) (41)
- Serial [5+2]/[4+2] Cycloadditions: Facile, Preparative, Multi-Component Syntheses of Polycyclic Compounds from Simple, Readily Available Starting Materials. (2001) (41)
- Highly efficient, facile, room temperature intermolecular [5 + 2] cycloadditions catalyzed by cationic rhodium(I): one step to cycloheptenes and their libraries. (2010) (40)
- Studies on tumor promoters: the first synthesis of the phorbol skeleton (1987) (40)
- Transition Metal-Catalyzed Intramolecular [4 + 2] Cycloadditions: Initial Studies on Stereochemistry and on Steroid and Vitamin D Analog Syntheses (1995) (39)
- Organobis(cuprates): a new class of reagents and method for spiroannelation (1988) (39)
- Intramolecular photoinduced diene-diene cyaloadditions: a selective method for the synthesis of complex eight-membered rings and polyquinanes (1987) (38)
- Total synthesis and initial biological evaluation of new B-ring-modified bryostatin analogs. (2006) (38)
- Inspirations from nature. New reactions, new therapeutic leads, and new drug delivery systems (2003) (37)
- Synthetic studies on areneolefin cycloadditions -VI- two syntheses of (±)-coriolin. (1983) (37)
- Total synthesis of (.+-.)-isabelin (1980) (37)
- A facile route to divinylcyclopropanes. An efficient method for the annelative formation of functionalized cycloheptanes (1976) (37)
- Towards the Ideal Synthesis (1998) (36)
- Synthesis and Biological Activities of New Conformationally Restricted Analogues of (−)-Indolactam-V: Elucidation of the Biologically Active Conformation of the Tumor-Promoting Teleocidins (1996) (35)
- Nickel(0)-Catalyzed Intramolecular [4 + 4] Cycloadditions: 5. The Type II Reaction in the Synthesis of Bicyclo[5.3.1]undecadienes (1991) (35)
- Isoapoptolidin: structure and activity of the ring-expanded isomer of apoptolidin. (2002) (35)
- Function-oriented synthesis: studies aimed at the synthesis and mode of action of 1alpha-alkyldaphnane analogues. (2007) (35)
- Synthesis and biological evaluation of fully synthetic bryostatin analogues (1998) (34)
- Synthetic studies on arene-olefin cycloadditions-VIII. Total syntheses of (±)-silphiperfol-6-ene, (±)-7 α H-silphiperfol-5-ene and (±)-7 β H-silphiperfol-5-ene☆ (1985) (34)
- Triazole Photonucleases: A New Family of Light Activatable DNA Cleaving Agents (1996) (33)
- Rhodium(I)‐Catalyzed [5+2], [6+2], and [5+2+1] Cycloadditions: New Reactions for Organic Synthesis (2005) (33)
- Regiospecific generation of lithioenamines from .alpha.,.beta.-unsaturated imines. An alternative method for reduction-alkylation of enones (1978) (33)
- An arene-alkene photocycloaddition-radical cyclization cascade: The first syntheses of cis,cis,cis,trans-[5.5.5.5]-fenestranes (1996) (33)
- “Picolog,” a Synthetically-Available Bryostatin Analog, Inhibits Growth of MYC-Induced Lymphoma In Vivo (2012) (33)
- Synthesis and biological evaluation of bryostatin analogues: the role of the A-ring (2000) (32)
- Function‐Oriented Synthesis, Step Economy, and Drug Design (2008) (32)
- Characterization of designed, synthetically accessible bryostatin analog HIV latency reversing agents (2018) (31)
- A new synthetic approach to the C ring of known as well as novel bryostatin analogues. (2003) (31)
- Synthesis and PKC binding of a new class of a-ring diversifiable bryostatin analogues utilizing a double asymmetric hydrogenation and cross-coupling strategy. (2006) (31)
- Studies on tumor promoters. 10. Synthesis of the abc ring system of the tiglianes and daphnanes by a zirconium-mediated intramolecular enyne carbocyclization (1990) (31)
- Peptide delivery to tissues via reversibly linked protein transduction sequences. (2002) (31)
- Prolonging microtubule dysruption enhances the immunogenicity of chronic lymphocytic leukaemia cells (2009) (30)
- Computer-Guided Design, Synthesis, and Protein Kinase C Affinity of a New Salicylate-Based Class of Bryostatin Analogs (2014) (29)
- Olefin metathesis-transannular ene sequence. A method for the stereocontrolled synthesis of trans-decalin derivatives. 1. Total synthesis of (.+-.)-calameon (1980) (29)
- Inhibition of Chikungunya Virus-Induced Cell Death by Salicylate-Derived Bryostatin Analogues Provides Additional Evidence for a PKC-Independent Pathway. (2016) (29)
- Combinations of isoform-targeted histone deacetylase inhibitors and bryostatin analogues display remarkable potency to activate latent HIV without global T-cell activation (2017) (29)
- Apoptolidins B and C: isolation, structure determination, and biological activity. (2005) (29)
- A formal synthesis of crinipellin B based on the arene-alkene meta-photocycloaddition reaction (1998) (29)
- A concise, selective synthesis of the polyketide spacer domain of a potent bryostatin analogue. (2003) (29)
- Seven-membered ring synthesis based on arene olefin cycloadditions: The total synthesis of (±)-Rudmollin (1986) (29)
- Apoptolidins E and F, new glycosylated macrolactones isolated from Nocardiopsis sp. (2009) (28)
- Design, synthesis, and biological evaluation of a potent, PKC selective, B-ring analog of bryostatin. (2006) (28)
- Methods for the preparations of 1,5-dienes. A metathetical route to medium-sized carbocycles (1977) (28)
- Hetero-atom substituted chromium allyls: Synthetic studies on neocarzinostatin chromophore analogues (1990) (27)
- Beyond cell penetrating peptides: designed molecular transporters. (2012) (27)
- Catalytic Efficiency Is a Function of How Rhodium(I) (5 + 2) Catalysts Accommodate a Conserved Substrate Transition State Geometry: Induced Fit Model for Explaining Transition Metal Catalysis. (2015) (27)
- The intramolecular addition of silylated alkynes to aldehydes: Methodology for the construction of cyclic enediynes and its application to dynemicin analogs (1995) (27)
- Synthesis and biological evaluation of a new class of bryostatin analogues: the role of the C20 substituent in protein kinase C binding (2000) (27)
- REDOR NMR Reveals Multiple Conformers for a Protein Kinase C Ligand in a Membrane Environment (2018) (27)
- Studies on DNA cleaving agents : synthesis and chemically induced cycloaromatization of a monocyclic neocarzinostatin chromophore analogue (1991) (26)
- Identification, activity, and structural studies of peptides incorporating the phorbol ester-binding domain of protein kinase C. (1995) (26)
- Tetramethyleneethane Equivalents: Recursive Reagents for Serialized Cycloadditions (2015) (26)
- Taxol-oligoarginine conjugates overcome drug resistance in-vitro in human ovarian carcinoma. (2012) (26)
- Vault Nanoparticles: Chemical Modifications for Imaging and Enhanced Delivery. (2017) (25)
- Toward the synthesis of the taxol C,D, ring system: Photolysis of α-methoxy ketones (1992) (25)
- Total synthesis and biological evaluation of 11-desmethyllaulimalide, a highly potent simplified laulimalide analogue. (2006) (25)
- Toward a structure-activity relationship for apoptolidin: selective functionalization of the hydroxyl group array. (2003) (25)
- Synthetic studies on arene-olefin cycloadditions - V. total synthesis of (±)-isoiridomyrmecin.☆ (1983) (25)
- An approach to the tiglianes, daphnanes, and ingenanes via the divinylcyclopropane rearrangement (1980) (25)
- The olefin metathesis/transannular ene sequence: a method for the stereocontrolled synthesis of -decalin derivatives. 3. total synthesis of (±)-warburganal (1982) (25)
- General methodology for cis-hydroisoquinoline synthesis. III: A sixteen step synthesis of reserpine (1987) (24)
- Identification of a tunable site in bryostatin analogs: C20 Bryologs through late stage diversification. (2005) (24)
- Facile synthetic access to and biological evaluation of the macrocyclic core of apoptolidin. (2003) (24)
- Role of the A-ring of bryostatin analogues in PKC binding: synthesis and initial biological evaluation of new A-ring-modified bryologs. (2005) (24)
- Pharmacophore mapping in the laulimalide series: total synthesis of a vinylogue for a late-stage metathesis diversification strategy. (2006) (24)
- Correlation of F0F1-ATPase inhibition and antiproliferative activity of apoptolidin analogues. (2006) (24)
- Simplified analogs of bryostatin with anticancer activity display greater potency for translocation of PKCdelta-GFP. (2004) (24)
- General methodology for cis-hydroisoquinoline synthesis: synthesis of reserpine (1980) (23)
- Functional DNA Delivery Enabled by Lipid-Modified Charge-Altering Releasable Transporters (CARTs). (2018) (23)
- GENERAL METHODOLOGY FOR CIS‐HYDROISOQUINOLINE SYNTHESIS: SYNTHESIS OF RESERPINE (2002) (23)
- Toward a biorelevant structure of protein kinase C bound modulators: design, synthesis, and evaluation of labeled bryostatin analogues for analysis with rotational echo double resonance NMR spectroscopy. (2015) (23)
- Synthetic bryostatin analogues activate the RasGRP1 signaling pathway. (2004) (23)
- Effect of Serum and Antioxidants on the Immunogenicity of Protein Kinase C-Activated Chronic Lymphocytic Leukemia Cells (2005) (23)
- The synthesis and chemistry of a simplified, functional analogue of neocarzinostatin chromophore: identification of an intramolecular 1,5-hydrogen atom (1994) (23)
- Sequence Specific DNA Cleavage by Conjugates of Benzotriazoles and Minor Groove Binders (1997) (22)
- Methyldialkylcyanodiazenecarboxylates as intermediates for transforming aliphatic ketones into nitriles (1977) (22)
- Studies on DNA-cleaving agents: computer modeling analysis of the mechanism of activation and cleavage of dynemicin-oligonucleotide complexes. (1991) (22)
- Engineering circular RNA for enhanced protein production (2022) (22)
- Propargyltrimethylsilanes as Allene Equivalents in Transition Metal-Catalyzed [5 + 2] Cycloadditions (2014) (22)
- Synthesis and evaluation of designed PKC modulators for enhanced cancer immunotherapy (2020) (22)
- Comparison of chemical characteristics of the first and the second cysteine-rich domains of protein kinase C gamma. (1997) (21)
- Beyond Cell Penetrating Peptides: Designed Molecular Transporters. (2012) (21)
- [3 + 2] and [5 + 2] Arene–Alkene Photocycloadditions (1991) (21)
- Prodrugs of PKC modulators show enhanced HIV latency reversal and an expanded therapeutic window (2020) (21)
- Indole synthesis based on triazole photochemistry: Total synthesis of7-methoxymitosene☆ (1987) (20)
- The olefin metathesis-transannular ene sequence: a method for the stereocontrolled synthesis of trans-decalin derivatives. 2. Formal eudesmane syntheses (1980) (20)
- Total synthesis of quadrone and terrecyclic acid A (1985) (20)
- Function-oriented synthesis: biological evaluation of laulimalide analogues derived from a last step cross metathesis diversification strategy. (2008) (20)
- Toward the Ideal Synthesis: Connectivity Analysis and Multibond‐ Forming Processes (1994) (20)
- Improved Protein Kinase C Affinity through Final Step Diversification of a Simplified Salicylate-Derived Bryostatin Analog Scaffold (2014) (20)
- Synthesis and phorbol ester-binding studies of the individual cysteine-rich motifs of protein kinase D. (1999) (19)
- Imine prototropy: synthetic consequences in the generation of metalloenamines (1978) (19)
- Guanidinium-rich, glycerol-derived oligocarbonates: a new class of cell-penetrating molecular transporters that complex, deliver, and release siRNA. (2015) (19)
- A Phosphoramidite Analogue of Cyclotriphosphate Enables Iterative Polyphosphorylations. (2019) (19)
- Charge-altering releasable transporters enable phenotypic manipulation of natural killer cells for cancer immunotherapy. (2020) (19)
- Latency reversal plus natural killer cells diminish HIV reservoir in vivo (2022) (19)
- Isolation, Structure Determination, and Anti-Cancer Activity of Apoptolidin D (2007) (19)
- Clinical correlates of HIV-1 DNA and inducible HIV-1 RNA reservoirs in peripheral blood in children with perinatally acquired HIV-1 infection with sustained virologic suppression for at least 5 years. (2020) (18)
- Ynol Ethers as Ketene Equivalents in Rhodium-Catalyzed Intermolecular [5 + 2] Cycloaddition Reactions. (2017) (18)
- Synthesis of modified nucleoside oligophosphates simplified: Fast, pure, and protecting group free. (2019) (18)
- Bromoacetophenone-based photonucleases: photoinduced cleavage of DNA by 4'-bromoacetophenone-pyrrolecarboxamide conjugates. (1999) (18)
- Rhodium-Catalyzed [5+2] Cycloaddition Reactions in Water (2003) (18)
- Base-induced decomposition of methyl dialkylcyanodiazenecarboxylates. Transformation of ketones into nitriles, .alpha.-carbomethoxynitriles, and .alpha.-methylnitriles (1971) (18)
- Solid-phase synthesis, mass spectrometric analysis of the zinc-folding, and phorbol ester-binding studies of the 116-mer peptide containing the tandem cysteine-rich C1 domains of protein kinase C gamma. (1999) (18)
- Methodology for indole synthesis (1981) (17)
- A photochemically mediated [4C + 2C] annelation. Synthesis of (.+-.)-10-epijunenol (1978) (17)
- A Second Generation Photochemically Activatable Dynemicin Analog: A Concise Synthesis and DNA Cleavage Studies (1994) (17)
- Delivery of Inorganic Polyphosphate into Cells Using Amphipathic Oligocarbonate Transporters (2018) (16)
- C–C Bond Formation (Part 1) by Addition Reactions: Higher-order Cycloadditions (2007) (16)
- Beyond Natural Products: Synthetic Analogues of Bryostatin 1 (2006) (16)
- DISCOVERY OF A NEW FRAGMENTATION REACTION (1990) (15)
- MACROEXPANSION METHODOLOGY: AN EFFICIENT EIGHT UNIT RING EXPANSION (1981) (15)
- Reversible RNA acylation for control of CRISPR–Cas9 gene editing† (2019) (15)
- Simplified Bryostatin Analogues Protect Cells from Chikungunya Virus-Induced Cell Death (2016) (15)
- Synthesis and mechanistic investigations of pH-responsive cationic poly(aminoester)s† (2020) (14)
- A general method for -hydroisoquinoline synthesis (1979) (14)
- A Gateway Synthesis, PKC Affinities and Cell Growth Activities of Daphnane Congeners (2011) (14)
- Function Oriented Synthesis: Preparation and Initial Biological Evaluation of New A-Ring-Modified Bryologs. (2011) (14)
- An mRNA SARS-CoV-2 Vaccine Employing Charge-Altering Releasable Transporters with a TLR-9 Agonist Induces Neutralizing Antibodies and T Cell Memory (2021) (14)
- Selective binding of bryostatin analogues to the cysteine rich domains of protein kinase C isozymes. (1999) (14)
- Rhodium(I)-Catalyzed [2+2], [2+2+2], and [2+2+2+2] Cycloadditions of Dienes or Alkynes with a Bis-ene (2009) (13)
- Rethinking the Role of Natural Products: Function‐Oriented Synthesis, Bryostatin, and Bryologs (2014) (13)
- The C4 hydroxyl group of phorbol esters is not necessary for protein kinase C binding. (2001) (13)
- The pinene path to taxol: Readily accessible a-ring building blocks based on novel alkyl- and alkenyllithium reagents with internal carbonyl groups (1995) (13)
- The chemistry-medicine continuum: Synthetic, computer, spectroscopic and biological studies on new chemotherapeutic leads (1998) (12)
- Synthesis and PKC isozyme surrogate binding of indothiolactam-V, a new thioamide analogue of tumor promoting indolactam-V. (2000) (12)
- Bryostatin 1 Promotes Synaptogenesis and Reduces Dendritic Spine Density in Cortical Cultures through a PKC-Dependent Mechanism. (2020) (12)
- Breaching biological barriers: protein translocation domains as tools for molecular imaging and therapy. (2003) (12)
- An mRNA SARS-CoV-2 vaccine employing Charge-Altering Releasable Transporters with a TLR-9 agonist induces neutralizing antibodies and T cell memory (2021) (11)
- The Pinene Path to Taxanes. 4. Approaches to Taxol and Taxol Analogs through Elaboration of Aromatic C-Ring Precursors. (1996) (11)
- Studies on the regio- and diastereo-selective epoxidation of daphnanes and tiglianes. (2015) (11)
- Synthesis and biological activities of new conformationally fixed analogues of (−)-indolactam-V, the core structure of tumor-promoting teleocidins (1995) (11)
- Organobiscuprates. A single-step spiroannelation method (1977) (11)
- Mechanistic and computational studies of exocyclic stereocontrol in the synthesis of bryostatin-like cis-2,6-disubstituted 4-alkylidenetetrahydropyrans by Prins cyclization. (2013) (10)
- Synthesis and Characterization of New Photolabile Phorbol Esters for Affinity Labeling of Protein Kinase C (1996) (10)
- Synthesis and binding of photoaffinity ligand candidates for protein kinase C (1993) (10)
- Tracking HIV Rebound following Latency Reversal Using Barcoded HIV (2020) (10)
- In Situ Detection of Endogenous HIV Activation by Dynamic Nuclear Polarization NMR and Flow Cytometry (2020) (10)
- The stereospecific generation of the cis-vicinal methyls in eremophilane and valencane sesquiterpenes: The total synthesis of (±) eremophilone and (±) 7-epieremophilone. (1974) (10)
- Comparative analysis of the anti-chikungunya virus activity of novel bryostatin analogs confirms the existence of a PKC-independent mechanism. (2016) (9)
- Toward the synthesis of taxol and its analogs: Incorporation of non-aromatic C-rings in the pinene pathway (1995) (9)
- The First Formal Asymmetric Synthesis of Phorbol. (1997) (9)
- An enolate-accelerated Cope rearrangement (1985) (9)
- Lead Diversification through a Prins-Driven Macrocyclization Strategy: Application to C13-Diversified Bryostatin Analogues (2013) (9)
- Synthesis of novel taxol analogs and evaluation of their biological activities (1997) (8)
- A New and Practical Approach to the Synthesis of Taxol and Taxol Analogues: The Pinene Path. (1992) (7)
- Mapping Phorbol Ester Binding Domains of Protein Kinase C (PKC): The Design, Synthesis and Biological Activity of Novel Phorbol Ester Dimers (1999) (7)
- Synthesis and Tumor-promoting Activities of 12-Epi-phorbol-12,13-dibutyrate (2000) (7)
- Synthesis and characterization of the first cysteine-rich domain of novel protein kinase C (1997) (7)
- Impact of Treatment Interruption on HIV Reservoirs and Lymphocyte Subsets in Individuals Who Initiated Antiretroviral Therapy During the Early Phase of Infection. (2019) (7)
- Studies on tumor promoters: V. Complementary 1,4-stereocontrol in phorboid cycloheptene synthesis via the divinylcyclopropane rearrangement (1988) (7)
- IMINE PROTOTROPY- SYNTHETIC CONSEQUENCES IN THE GENERATION OF METALLOENAMINES (1978) (6)
- Function-Oriented Synthesis: Design, Synthesis, and Evaluation of Highly Simplified Bryostatin Analogues. (2020) (6)
- Photocleavage of DNA by 4′-bromoacetophenone analogs (2001) (6)
- Bryostatin analogue-induced apoptosis in mantle cell lymphoma cell lines. (2012) (6)
- In Vivo Targeting of Escherichia coli with Vancomycin-Arginine (2021) (6)
- Synthesis and characterization of the second cysteine-rich region of mouse skin PKCGh (1996) (6)
- Novel Oxidative Rearrangement Product of the First trans,cis,cis,cis-[5.5.5.5]Fenestrane Derivative (1997) (5)
- Transition Metal Catalyzed [5 + 2] Cycloadditions of Allenes and Vinylcyclopropanes: First Studies of endo—exo Selectivity, Chemoselectivity, Relative Stereochemistry, and Chirality Transfer. (2010) (5)
- Photoinduced cleavage of DNA by bromofluoroacetophenone-pyrrolecarboxamide conjugates. (2003) (5)
- Protein kinase C regulatory domain surrogate peptides : Effects of metal ions on folding, phorbol ester-binding, and selectivity (1997) (5)
- A new class of simplified phorbol ester analogues: synthesis and binding to PKC and eta PKC-C1B (eta PKC-CRD2). (1999) (5)
- Rh(I)-catalyzed cleavage of unactivated CO bonds Carbonylative rearrangement reactions of allenyl ethers to 2-carboalkoxy-1,3-dienes (2005) (5)
- Transition Metal-Catalyzed [5 + 2] Cycloadditions with Substituted Cyclopropanes: First Studies of Regio- and Stereoselectivity (2000) (5)
- A Phosphoramidite Analogue of Cyclotriphosphate Enables Iterative Polyphosphorylations (2019) (4)
- Isolation, structure determination, and anti-cancer activity of apoptolidin D. (2007) (4)
- Arene-Alkene Photocycloaddition Reactions (1990) (4)
- The Pinene Approach to Taxanes 2: Development of a Versatile C9, C10 Linker (1995) (4)
- Electronic and Steric Control of Regioselectivities in Rh(I)‐Catalyzed [5 + 2] Cycloadditions: Experiment and Theory. (2011) (4)
- The Synthesis of Seven‐Membered Rings: General Strategies and the Design and Development of a New Class of Cycloaddition Reactions (1999) (4)
- Bryostatin and its synthetic analog, picolog rescue dermal fibroblasts from prolonged stress and contribute to survival and rejuvenation of human skin equivalents (2018) (4)
- Designed PKC-targeting bryostatin analogs modulate innate immunity and neuroinflammation (2020) (4)
- Art, architecture, and the molecular frontier. (2015) (4)
- Three‐Component Cycloadditions: The First Transition Metal Catalyzed [5 + 2 + 1] Cycloaddition Reactions. (2002) (3)
- Synthesis of 1-(2-naphthoyl) benzotriazoles as photoactivated DNA cleaving agents (1997) (3)
- The Transition Metal‐Catalyzed Intermolecular [5 + 2] Cycloaddition: The Homologous Diels—Alder Reaction. (1999) (3)
- Charge-Altering Releasable Transporters Enable Specific Phenotypic Manipulation of Resting Primary Natural Killer Cells (2020) (3)
- The Preparation of Cyclohept‐4‐Enones by Rhodium‐Catalyzed Intermolecular [5+2] Cycloaddition (2012) (3)
- Rhodium Dinaphthocyclooctatetraene Complexes: Synthesis, Characterization and Catalytic Activity in [5 + 2] Cycloadditions. (2012) (3)
- Enantioselective synthesis of neocarzinostatin chromophore aglycon (1997) (3)
- Synthesis and Biological Activities of New Conformationally Restricted Analogues of (‐)‐Indolactam‐V: Elucidation of the Biologically Active Conformation of the Tumor‐Promoting Teleocidins. (2010) (3)
- Synthesis and binding studies of the 116-mer peptide containing the double cysteine-rich motifs of protein kinase C gamma (1998) (2)
- Toward the Ideal Synthesis: New Transition Metal catalyzed Reactions Inspired by Novel Medicinal Leads (2002) (2)
- Transition Metal‐Catalyzed [6 + 2] Cycloadditions of 2‐Vinylcyclobutanones and Alkenes: A New Reaction for the Synthesis of Eight‐Membered Rings. (2000) (2)
- Fingolimod-Conjugated Charge-Altering Releasable Transporters Efficiently and Specifically Deliver mRNA to Lymphocytes In Vivo and In Vitro. (2022) (2)
- The Photochemistry of 1-Alkenylbenzotriazoles Methodology for the Synthesis of Indoles. (1986) (2)
- Transition‐Metal‐Catalyzed Intramolecular (4 + 2) Diene‐Allene Cycloadditions: A Convenient Synthesis of Angularly Substituted Ring Systems with Provision for Catalyst‐Controlled Chemo‐ and Stereocomplementarity. (1995) (2)
- A New and Selective Catalyst for the [5 + 2] Cycloaddition of Vinylcyclopropanes and Alkynes. (1998) (2)
- Author Correction: Engineering circular RNA for enhanced protein production (2022) (2)
- Toward the Ideal Synthesis and Transformative Therapies: The Roles of Step Economy and Function Oriented Synthesis (2013) (2)
- Carbonyl(chloro)bis(triphenylphosphine)rhodium(I) (2001) (2)
- Synthesis and Biological Evaluation of a New Class of Bryostatin Analogues: The Role of the C20 Substituent in Protein Kinase C Binding. (2000) (2)
- RhI‐Catalyzed C—C Bond Activation: Seven‐Membered Ring Synthesis by a [6 + 1] Carbonylative Ring‐Expansion Reaction of Allenylcyclobutanes. (2006) (2)
- Rhodium‐Catalyzed [5 + 2] Cycloaddition Reactions in Water. (2003) (2)
- Chemistry, computers and carcinogenesis (1989) (2)
- A Photochemically Triggered DNA Cleaving Agent: Synthesis, Mechanistic and DNA Cleavage Studies on a New Analogue of the Antitumor Antibiotic Dynemicin. (1994) (2)
- Breaching Biological Barriers: Protein Translocation Domains as Tools for Molecular Imaging and Therapy (2003) (2)
- Design and synthesis of new DNA photocleavers, 4′-bromoacetophenone-pyrrolecarboxamide hybrid compounds (2000) (2)
- SYNTHETIC STUDIES ON ARENE‐OLEFIN CYCLOADDITIONS ‐ VII: A THREE‐STEP TOTAL SYNTHESIS OF (.+‐.)‐SILPHINENE (1985) (2)
- Molecular understanding of cellular uptake by arginine-rich cell penetrating peptides (2006) (2)
- Studies on Tumor Promoters. Part 11. A New (5 + 2)Cycloaddition Method and Its Applications to the Synthesis of BC Ring Precursors of Phoboids. (1992) (2)
- Rh(I)-Catalyzed Cleavage of Unactivated C—O Bonds — Carbonylative Rearrangement Reactions of Allenyl Ethers to 2-Carboalkoxy-1,3-dienes. (2006) (1)
- SYNTHETIC STUDIES ON ARENE-OLEFIN CYCLOADDITIONS. II. TOTAL SYNTHESIS OF (.+-.)-ISOCOMENE (1982) (1)
- Nitriles from Ketones: Cyclohexanecarbonitrile (2003) (1)
- Indole Synthesis Based on Triazole Photochemistry: Total Synthesis of 7-Methoxymitosene. (1988) (1)
- Metal-Catalyzed [2 + 2 + 1] Cycloadditions of 1,3-Dienes, Allenes, and CO. (2006) (1)
- A New and Practical Five‐Carbon Component for Metal‐Catalyzed [5 + 2] Cycloadditions: Preparative Scale Syntheses of Substituted Cycloheptenones. (2010) (1)
- Mechanistic Insights into Guanidinium-Rich Transporters Entering Cells (2006) (1)
- Studies on DNA-Cleaving Agents: Synthesis of a Functional Dynemicin Analogue. (1991) (1)
- Translating Nature's Library: Future Opportunities through Function Oriented Design (2013) (1)
- Toward the Synthesis of the Taxol C,D Ring System: Photolysis of . alpha.-Methoxy Ketones. (1992) (1)
- Practical synthesis of the therapeutic leads tigilanol tiglate and its analogues. (2022) (1)
- Seven-Membered Ring Synthesis Based on Arene Olefin Cycloadditions: The Total Synthesis of (±)-Rudmollin. (1986) (1)
- A PHOTOCHEMICALLY MEDIATED (4C + 2C) ANNELATION. SYNTHESIS OF (.+-.)-10-EPIJUNENOL (2002) (1)
- The First Intermolecular Transition Metal‐Catalyzed [5 + 2] Cycloadditions with Simple, Unactivated, Vinylcyclopropanes. (2001) (1)
- Highly Efficient, Facile, Room-Temperature Intermolecular [5 + 2] Cycloadditions Catalyzed by Cationic Rhodium(I): One Step to Cycloheptenes and Their Libraries. (2010) (1)
- Multicomponent Cycloadditions: The Four-Component [5 + 1 + 2 + 1] Cycloaddition of Vinylcyclopropanes, Alkynes, and CO. (2005) (1)
- Synthesis and PKC Isozyme Surrogate Binding of Indothiolactam‐V, a New Thioamide Analogue of Tumor Promoting Indolactam‐V. (2000) (1)
- Spiroannelation via Organobis(Cuprates): 9,9‐Dimethylspiro[4.5]Decan‐7‐One (2003) (1)
- Serial [5 + 2]/[4 + 2] Cycloadditions: Facile, Preparative, Multi‐Component Syntheses of Polycyclic Compounds from Simple, Readily Available Starting Materials. (2002) (1)
- Bis‐(1,5‐cyclooctadiene)nickel(0) (2006) (1)
- 2‐Alkenyl Carbinols from 2‐Halo Ketones: 2‐E‐Propenylcyclohexanol (2003) (1)
- Transition Metal Catalyzed Cycloadditions: An Intramolecular (4 + 4) Cycloaddition Strategy for the Efficient Synthesis of Dicyclopenta(a,d) cyclooctene 5‐8‐5 Ring Systems. (1997) (1)
- Synthetic Studies on Arene‐Olefin Cycloadditions. Part 12. Total Synthesis of (.+‐.)‐Subergorgic Acid (I). (1991) (1)
- Synthesis and Biological Evaluation of Bryostatin Analogues: The Role of the A-Ring. (2000) (1)
- Rhodium(I)‐Catalyzed [4 + 2 + 2] Cycloadditions of 1,3‐Dienes, Alkenes, and Alkynes for the Synthesis of Cyclooctadienes. (2006) (0)
- Total Synthesis of Quadrone and Terrecyclic Acid A1. (1986) (0)
- Intramolecular Nickel Catalyzed Cycloadditions of Bisdienes: 3 Approaches to the Taxane Skeleton. (1987) (0)
- N‐Alkoxyimidazolylidene Transition‐Metal Complexes. Application to [5 + 2] and [4 + 2] Cycloaddition Reactions. (2007) (0)
- Macroexpansion Methodology. Part 5. An Enolate‐Accelerated Cope Rearrangement. (1986) (0)
- Hetero‐Atom Substituted Chromium Allyls: Synthetic Studies on Neocarzinostatin (I) Analogues. (1992) (0)
- Macroexpansion Methodology. Part 3. Eight-Step Synthesis of (-)-(3Z)-Cembrene A. (1986) (0)
- Transition Metal‐Catalyzed Intramolecular [4 + 2] Cycloadditions: Mechanistic and Synthetic Investigations. (1998) (0)
- Synthesis and evaluation of designed PKC modulators for enhanced cancer immunotherapy (2020) (0)
- Comprehensive analysis of HIV reservoirs in elite controllers (2023) (0)
- A Second Generation Photochemically Activatable Dynemicin Analogue: A Concise Synthesis and DNA Cleavage Studies. (2010) (0)
- The Synthesis of Highly Substituted Cyclooctatetraene Scaffolds by Metal-Catalyzed [2 + 2 + 2 + 2] Cycloadditions: Studies on Regioselectivity, Dynamic Properties, and Metal Chelation. (2010) (0)
- A Formal Synthesis of Crinipellin B Based on the Arene—Alkene meta-Photocycloaddition Reaction. (1999) (0)
- Novel Oxidative Rearrangement Product of the First trans,cis,cis,cis‐( 5.5.5.5)Fenestrane Derivative. (2010) (0)
- MACROEXPANSION METHODOLOGY. PART 2. MEDIUM-RING SYNTHESIS BASED ON AN EIGHT-UNIT RING-EXPANSION PROCESS (1982) (0)
- Organobis(cuprates): A New Class of Reagents and Method for Spiroanellation. (1988) (0)
- Preparation and Cycloadditions of a 4-Methoxy-3-oxidopyrylium Ylid: A Reagent for the Synthesis of Highly Substituted Seven-Membered Rings and Tetrahydrofurans. (2010) (0)
- The Pinene Path to Taxanes: Genesis and Evolution of a Strategy for Synthesis (1994) (0)
- The Pinene Path to Taxol: Readily Accessible A‐Ring Building Blocks Based on Novel Alkyl‐ and Alkenyllithium Reagents with Internal Carbonyl Groups. (2010) (0)
- Analogues de laulimalide en tant qu'agents therapeutiques (2005) (0)
- Bis(acrylonitrile)nickel(0) (2001) (0)
- The Dienyl Pauson—Khand Reaction. (2003) (0)
- Trimethylene Methane Dianion Equivalent for the Asymmetric Consecutive Allylation of Aldehydes: Applications to Prins-Driven Macrocyclizations for the Synthesis of Bryostatin 1 and Analogues. (2022) (0)
- Apicomplexan pathways, inhibitors, and drug delivery (2005) (0)
- Transition Metal Catalyzed Intramolecular (4 + 2) Cycloadditions: A Novel Method for the Assembly of Nitrogen Heterocycles and Its Application to Yohimban Alkaloid Synthesis. (1996) (0)
- Apoptolidines E (I) and F (II), New Glycosylated Macrolactones Isolated from Nocardiopsis sp. (2010) (0)
- Rhodium-Catalyzed [5+2] Cycloaddition-NazarovCyclization Strategy (2010) (0)
- Nickel-Catalyzed Intramolecular (4 + 2) Dienyne Cycloadditions: An Efficient New Method for the Synthesis of Polycycles Containing Cyclohexa-1,4-dienes. (1989) (0)
- Synthesis of Novel Taxol Analogues and Evaluation of Their Biological Activities. (1997) (0)
- PRACTICAL METHOD FOR α‐ALKENYL KETONE SYNTHESIS BASED ON A FACILE REDUCTIVE REARRANGEMENT OF ALKYNYL HALOHYDRINS (1983) (0)
- A general method for cis-hydroisoquinoline synthesis (1979) (0)
- THE STEREOSPECIFIC GENERATION OF THE CIS-VICINAL METHYLS IN EREMOPHILANE AND VALENCANE SESQUITERPENES, THE TOTAL SYNTHESIS OF (+-)EREMOPHILONE AND (+-)7 EPIEREMOPHILONE (1974) (0)
- Studies on Tumor Promoters. The First Synthesis of the Phorbol Skeleton. (1987) (0)
- 1,4‐Dibromobutane (2001) (0)
- Barcoded HIV reveals effects of PKC modulation on viral reservoir (2019) (0)
- Discovery of a New Fragmentation Reaction. (1991) (0)
- Synthesis and Biological Activities of New Conformationally Fixed Analogues of (-)-Indolactam-V, the Core Structure of Tumor-Promoting Teleocidins. (1995) (0)
- SYNTHETIC STUDIES ON ARENE‐OLEFIN CYCLOADDITIONS ‐ V. TOTAL SYNTHESIS OF (.+‐.)‐ISOIRIDOMYRMECIN (1984) (0)
- AN APPROACH TO THE TIGLIANES, DAPHANES, AND INGENANES VIA THE DIVINYLCYCLOPROPANE REARRANGEMENT (1980) (0)
- Toward the Total Synthesis of Taxol and its Analogues (1996) (0)
- Nickel(0)-Catalyzed Intramolecular (4 + 4)Cycloadditions. Part 5. The Type II Reaction in the Synthesis of Bicyclo(5.3.1)undecadienes. (1992) (0)
- Dicyanobis(triphenylphosphine)nickel(II) (2001) (0)
- 13 – Structural Design in Antitumor Compounds (1991) (0)
- Tumor Promoters. Part 7. The Synthesis of a Potentially General Precursor of the Tiglianes, Daphnanes, and Ingenanes. (1990) (0)
- Editorial: To Eun Lee on His 65th Birthday (2011) (0)
- The Synthesis and Chemistry of a Simplified, Functional Analogue of Neocarzinostatin Chromophore: Identification of an Intramolecular 1,5‐ Hydrogen Atom Transfer Relevant to the Mechanism and Cleavage Selectivity of Diyl‐Based DNA Cleaving Agents. (1994) (0)
- A Metal‐Catalyzed Intermolecular [5 + 2] Cycloaddition/Nazarov Cyclization Sequence and Cascade. (2010) (0)
- C4QO00228H 1166..1171 ++ (2014) (0)
- Intermolecular Dienyl Pauson—Khand Reaction. (2004) (0)
- Rhodium(I)‐Catalyzed [2 + 2 + 1] Cycloadditions of 1,3‐Dienes, Alkenes, and CO. (2004) (0)
- Analogues de la bryostatine, methodes de synthese et utilisations (2000) (0)
- ORGANOBISCUPRATES. A SINGLE-STEP SPIROANNULATION METHOD (1977) (0)
- Nickel-Catalyzed Intramolecular (4 + 4) Cycloadditions. Part 2. Allylic Stereoinduction and Modeling Studies in the Preparation of Bicyclo-(6.4.0)dodecadienes. (1987) (0)
- BASENINDUZIERTE ZERS. VON DIALKYLCYANDIAZENCARBONSAEUREMETHYLESTERN, UMWANDLUNG VON KETONEN IN NITRILE, ALPHA-METHOXYCARBONYL- UND ALPHA-METHYL-NITRILE (1971) (0)
- Nickel-Catalyzed Intramolecular (4 + 4)Cycloadditions. Part 4. Enantioselective Total Synthesis of (+)-Asteriscanolide. (1988) (0)
- Tris(triphenylphosphine)nickel(0) (2001) (0)
- General Methodology for cis-Hydroisoquinoline Synthesis. Part 3. A Sixteen Step Synthesis of Reserpine (I). (1987) (0)
- Synthetic Studies on Arene-Olefin Cycloadditions. Part 3. Total Synthesis of (±)-Hirsutene. (1983) (0)
- Isolation of Diazacycloheptatetraenes from Thermal Nitrene-Nitrene Rearrangements' (1980) (0)
- Serial [5+2]/[4+2] Cycloadditions: Facile, Preparative, Multi-Component Syntheses of Polycyclic Compounds from Simple, Readily Available Starting Materials This research was supported by grant CHE-9800445 from the National Science Foundation. The Stanford Graduate Fellowship (M.J.C.S. and G.G.G.) is (2001) (0)
- Asymmetric [5+2] Cycloaddition of Vinylcyclopropanes and π-Systems (2006) (0)
- Nickel-Catalyzed Intramolecular [4 + 4] Cycloadditions: A New Method for the Synthesis of Polycycles Containing Eight-Membered Rings. (1986) (0)
- Transition Metal‐Catalyzed Intermolecular [5 + 2] and [5 + 2 + 1] Cycloadditions of Allenes and Vinylcyclopropanes. (2005) (0)
- Structural Complexity Through Multicomponent Cycloaddition Cascades Enabled by Dual-Purpose, Reactivity Regenerating (2014) (0)
- REGIOSPECIFIC GENERATION OF LITHIOENAMINES FROM α,β-UNSATURATED IMINES. AN ALTERNATIVE METHOD FOR REDUCTION-ALKYLATION OF ENONES (1978) (0)
- Molecular dynamics simulations reveal ligand-controlled positioning of a peripheral protein complex in membranes (2017) (0)
- Correction to "Synthesis of Modified Nucleoside Oligophosphates Simplified: Fast, Pure, and Protecting Group Free". (2019) (0)
- Tetrakis(trichlorophosphine)nickel(0) (2001) (0)
- Synthesis and Biological Evaluation of Fully Synthetic Bryostatin Analogues. (1999) (0)
- Pinene Approach to Taxanes. Part 2. Development of a Versatile C9, C10 Linker. (1995) (0)
- Gilbert Stork (1921–2017) (2017) (0)
- Tetramethyleneethane Equivalents: Recursive Reagents for Serialized Cycloadditions. (2015) (0)
- An Arene-Alkene Photocycloaddition-Radical Cyclization Cascade: The First Syntheses of cis,cis,cis,trans-(5.5.5.5)-Fenestranes. (1997) (0)
- PP 2.13 – 00160 Enhancing Tolerability and Efficacy of Latency Reversing Agents in “Kick and Kill” HIV Cure Approaches (2022) (0)
- Overcoming Clear Cell Ovarian Cancer Resistance to Taxol by an Oligo Arginine Transporter Conjugate (2017) (0)
- Transition Metal Catalyzed Intramolecular (4 + 2) Cycloadditions: Initial Studies on Stereochemistry and on Steroid and Vitamin D Analogue Syntheses. (1995) (0)
- Silver-Catalyzed Synthesis of 2,3-Dihydro-pyrroles (2009) (0)
- Intramolecular Photoinduced Diene-Diene Cycloadditions: A Selective Method for the Synthesis of Complex Eight-Membered Rings and Polyquinanes. (1987) (0)
- The Intramolecular Addition of Silylated Alkynes to Aldehydes: Methodology for the Construction of Cyclic Enediynes and Its Application to Dynemicin Analogues. (1995) (0)
- General Methodology for the Synthesis of Neocarzinostatin Chromophore Analogues: Intramolecular Chromium-Mediated Closures for Strained-Ring Synthesis. (1990) (0)
- Combinations of isoform-targeted histone deacetylase inhibitors and bryostatin analogues display remarkable potency to activate latent HIV without global T-cell activation (2017) (0)
- Synthesis of Bryostatin Analogues (2008) (0)
- Tumor Promotion: Pharmacological and Synthetic Studies (1987) (0)
- Tumor Promoters. Part 8. The Synthesis of Phorbol. (1990) (0)
- Tetrakis(triphenylphosphine)nickel(0) (2001) (0)
- poster session 1: new drug targets, drug design and drug discovery P.101 INHIBITION OF FURIN RESULTS IN DECREASED TUMOR CELL GROWTH (2006) (0)
- Synthetic Studies on Arene-Olefin Cycloadditions. Part 10. A Concise, Stereocontrolled Total Synthesis of (.+-.)-Laurenene. (1988) (0)
- Aromatic Compounds: Isomerization and Cycloaddition (1987) (0)
- The Diene Effect: The Design, Development, and Mechanistic Investigation of Metal‐Catalyzed Diene‐yne, Diene‐ene, and Diene‐allene [2 + 2 +1] Cycloaddition Reactions. (2010) (0)
- Latency reversal plus natural killer cells diminish HIV reservoir in vivo (2022) (0)
- Tumor Promoters. Part 9. A Second-Generation Synthesis of Phorbol (1990) (0)
- Transition Metal Catalyzed (5 + 2) Cycloadditions of Vinylcyclopropanes and Alkynes: A Homologue of the Diels-Alder Reaction for the Synthesis of Seven-Membered Rings. (1995) (0)
- Transition Metal‐Catalyzed Hetero‐[5 + 2] Cycloadditions of Cyclopropyl Imines and Alkynes: Dehydroazepines from Simple, Readily Available Starting Materials. (2003) (0)
- Facile Synthesis of Stop-Sign Ene (2008) (0)
- Gilbert Stork (1921-2017). (2017) (0)
- Lysine-Derived Charge-Altering Releasable Transporters: Targeted Delivery of mRNA and siRNA to the Lungs. (2023) (0)
- Studies on Tumor Promoters. Part 5. Complementary 1,4-Stereocontrol in Phorboid Cycloheptene Synthesis via the Divinylcyclopropane Rearrangement. (1989) (0)
- The First Metal-Catalyzed Intramolecular [5 + 2] Cycloadditions of Vinylcyclopropanes and Alkenes: Scope, Stereochemistry, and Asymmetric Catalysis. (1998) (0)
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