Paul Zamecnik
American geneticist
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Biology
Paul Zamecnik's Degrees
- Doctorate Medicine Harvard University
Why Is Paul Zamecnik Influential?
(Suggest an Edit or Addition)According to Wikipedia, Paul Charles Zamecnik was an American scientist who played a central role in the early history of molecular biology. He was a professor of medicine at Harvard Medical School and a senior scientist at Massachusetts General Hospital. Zamecnik pioneered the in vitro synthesis of proteins and helped elucidate the way cells generate proteins. With Mahlon Hoagland he co-discovered transfer RNA . Through his later work, he is credited as the inventor of antisense therapeutics. Throughout his career, Zamecnik earned over a dozen US patents for his therapeutic techniques. Up until his death in 2009 he maintained a lab at MGH where he studied the application of synthetic oligonucleotides for chemotherapeutic treatment of drug resistant and XDR tuberculosis in his later years.
Paul Zamecnik's Published Works
Published Works
- Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide. (1978) (1413)
- Inhibition of Rous sarcoma viral RNA translation by a specific oligodeoxyribonucleotide. (1978) (724)
- A soluble ribonucleic acid intermediate in protein synthesis. (1958) (612)
- Detection of nucleic acid hybridization by nonradiative fluorescence resonance energy transfer. (1988) (427)
- Enzymatic carboxyl activation of amino acids. (1956) (378)
- The effect of guanosine diphosphate and triphosphate on the incorporation of labeled amino acids into proteins. (1956) (319)
- Studies on cytoplasmic ribonucleoprotein particles from the liver of the rat. (1955) (316)
- Inhibition of replication and expression of human T-cell lymphotropic virus type III in cultured cells by exogenous synthetic oligonucleotides complementary to viral RNA. (1986) (298)
- Intermediate reactions in protein biosynthesis. (1957) (282)
- Relation between phosphate energy donors and incorporation of labeled amino acids into proteins. (1954) (257)
- The effect of puromycin on rabbit reticulocyte ribosomes. (1962) (248)
- Enzymatic synthesis of diadenosine tetraphosphate and diadenosine triphosphate with a purified lysyl-sRNA synthetase. (1966) (216)
- The preparation and some properties of a low molecular weight ribonucleic acid from baker's yeast. (1960) (213)
- Oligodeoxynucleoside phosphoramidates and phosphorothioates as inhibitors of human immunodeficiency virus. (1988) (213)
- Presence of diadenosine 5',5''' -P1, P4-tetraphosphate (Ap4A) in mamalian cells in levels varying widely with proliferative activity of the tissue: a possible positive "pleiotypic activator". (1976) (213)
- Inhibition of human immunodeficiency virus replication by antisense oligodeoxynucleotides. (1988) (192)
- Inhibition of human immunodeficiency virus in early infected and chronically infected cells by antisense oligodeoxynucleotides and their phosphorothioate analogues. (1989) (160)
- Nucleoside tri-phosphates as precursors of ribonucleic acid end groups in a mammalian system. (1958) (151)
- Diadenosine 5',5"'-P1,P4-tetraphosphate (Ap4A): its role in cellular metabolism. (1983) (141)
- Treatment of Mycobacterium tuberculosis with antisense oligonucleotides to glutamine synthetase mRNA inhibits glutamine synthetase activity, formation of the poly-L-glutamate/glutamine cell wall structure, and bacterial replication. (2000) (138)
- ON THE STABILITY OF AMINOACYL-S-RNA TO NUCLEOPHILIC CATALYSIS. (1964) (122)
- Site-specific excision from RNA by RNase H and mixed-phosphate-backbone oligodeoxynucleotides. (1990) (119)
- Inhibition of acquired immunodeficiency syndrome virus by oligodeoxynucleoside methylphosphonates. (1988) (107)
- Cupric ion catalysis in hydrolysis of aminoacyl-tRNA. (1968) (107)
- Specific inhibition of human immunodeficiency virus type 1 replication by antisense oligonucleotides: an in vitro model for treatment. (1992) (105)
- Isolation and characterization of dinucleoside tetra- and tri-phosphates formed in the presence of lysyl-sRNA synthetase. (1966) (105)
- Incorporation of C14-amino acids into proteins of leaf disks and cell-free fractions of tobacco leaves. (1956) (105)
- Amino acid incorporation into protein by extracts of E. coli. (1960) (98)
- Rous sarcoma virus genome is terminally redundant: the 3' sequence. (1977) (93)
- Long-term treatment of human immunodeficiency virus-infected cells with antisense oligonucleotide phosphorothioates. (1993) (92)
- Ribosomes and protein synthesis (1981) (87)
- Studies on the carbohydrate and protein metabolism of the rat hepatoma. (1951) (85)
- A MANOMETRIC METHOD FOR MEASURING THE ACTIVITY OF THE CL. WELCHII LECITHINASE AND A DESCRIPTION OF CERTAIN PROPERTIES OF THIS ENZYME (1947) (82)
- THE ROLE OF MICROSOMES IN THE INCORPORATION OF AMINO ACIDS INTO PROTEINS (1954) (81)
- BINDING OF AMINO ACIDS TO THE END GROUP OF A SOLUBLE RIBONUCLEIC ACID. (1959) (80)
- Targeting the Mycobacterium tuberculosis 30/32-kDa mycolyl transferase complex as a therapeutic strategy against tuberculosis: Proof of principle by using antisense technology (2002) (75)
- HeLa cell DNA polymerase alpha is tightly associated with tryptophanyl-tRNA synthetase and diadenosine 5',5"'-P1,P4-tetraphosphate binding activities. (1981) (68)
- A hydrolytic procedure for ribonucleosides and its possible application to the sequential degradation of RNA. (1960) (68)
- Inhibition of influenza virus replication by phosphorothioate oligodeoxynucleotides. (1990) (67)
- Association of diadenosine 5',5"'-P1,P4-tetraphosphate binding protein with HeLa cell DNA polymerase alpha. (1981) (64)
- Analogues of diadenosine 5',5'''-P1,P4-tetraphosphate (Ap4A) as potential anti-platelet-aggregation agents. (1992) (62)
- Mechanism of incorporation of labeled amino acids into protein. (1956) (57)
- Oxygen transfer to AMP in the enzymic synthesis of the hydroxamate of tryptophan. (1957) (57)
- An historical account of protein synthesis, with current overtones--a personalized view. (1969) (55)
- Fluorescence resonance energy transfer in near-infrared fluorescent oligonucleotide probes for detecting protein–DNA interactions (2008) (55)
- PARTIAL PURIFICATION OF SOLUBLE RNA. (1960) (52)
- EXPERIMENTAL DEMYELINATION BY MEANS OF ENZYMES, ESPECIALLY THE ALPHA TOXIN OF CLOSTRIDIUM WELCHII (1950) (51)
- Regulation of DNA replication in S phase nuclei by ATP and ADP pools. (1979) (51)
- Electron micrographic studies of transport of oligodeoxynucleotides across eukaryotic cell membranes. (1994) (50)
- Antimalarial activities of oligodeoxynucleotide phosphorothioates in chloroquine-resistant Plasmodium falciparum. (1992) (50)
- Rapid noninvasive detection of experimental atherosclerotic lesions with novel 99mTc-labeled diadenosine tetraphosphates. (1998) (50)
- Priming of DNA synthesis by diadenosine 5',5"'-P1,P4-tetraphosphate with a double-stranded octadecamer as a template and DNA polymerase alpha. (1982) (50)
- Dependence of amino acid binding to soluble ribonucleic acid on cytidine triphosphate. (1958) (48)
- Contamination of Hodgkin's disease cell cultures (1981) (48)
- Medical Survey of Nutrition in Newfoundland. (1945) (47)
- Incorporation in vitro of radioactive carbon from carboxyl-labeled dl-alanine and glycine into proteins of normal and malignant rat livers. (1948) (46)
- Resolution of the diadenosine 5',5"'-P1,P4-tetraphosphate binding subunit from a multiprotein form of HeLa cell DNA polymerase alpha. (1983) (46)
- Inhibition of Plasmodium falciparum malaria using antisense oligodeoxynucleotides. (1996) (46)
- Intermediate Reactions in Amino Acid Incorporation. (1958) (44)
- The clearance and degradation of oligodeoxynucleotides following intravenous injection into rabbits. (1991) (42)
- ANOMALOUS ROTATORY DISPERSION OF SOLUBLE RIBONUCLEIC ACID AND ITS RELATION TO AMINO ACID SYNTHETASE RECOGNITION. (1965) (39)
- The effect of dinitrophenol on the incorporation of alanine labeled with radioactive carbon into the proteins of slices of normal and malignant rat liver. (1948) (39)
- Incorporation of adenosine into ATP: formation of compartmentalized ATP. (1976) (38)
- P1,P4-dithio-P2,P3-monochloromethylene diadenosine 5',5'''-P1,P4-tetraphosphate: a novel antiplatelet agent. (1997) (38)
- Reversal of cystic fibrosis phenotype in a cultured Delta508 cystic fibrosis transmembrane conductance regulator cell line by oligonucleotide insertion. (2004) (37)
- Antimycobacterial activities of antisense oligodeoxynucleotide phosphorothioates in drug-resistant strains. (1996) (37)
- Hairpin extensions enhance the efficacy of mycolyl transferase-specific antisense oligonucleotides targeting Mycobacterium tuberculosis (2007) (36)
- TRANSFORMATION OF BACTERIA INTO L FORMS BY AMINO ACIDS, (1952) (35)
- EFFECT OF BROMINATION ON THE AMINO ACID-ACCEPTING ACTIVITIES OF TRANSFER RIBONUCLEIC ACIDS. (1963) (35)
- Detection of inflamed atherosclerotic lesions with diadenosine-5′,5‴-P1,P4-tetraphosphate (Ap4A) and positron-emission tomography (2006) (34)
- Thiosine-resistant mutants of Escherichia coli K-12 with growth-medium-dependent lysl-tRNA synthetase activity. I. Isolation and physiological characterization. (1972) (34)
- Diadenosine 5',5'''-P1,P4-tetraphosphate, a potential antithrombotic agent. (1988) (33)
- PEPTIDASE ACTIVITY OF LYMPH AND SERUM AFTER BURNS (1945) (33)
- Site specific functionalization of oligonucleotides for attaching two different reporter groups. (1990) (32)
- Conformational differences between s-RNA and aminoacyl s-RNA. (1965) (32)
- Peptide bond synthesis in normal and malignant tissue. (1950) (32)
- A STUDY OF THE COMPETITION OF LECITHIN AND ANTITOXIN FOR CL. WELCHII LECITHINASE (1947) (31)
- Base composition differences between avian myeloblastosis virus transfer RNA and transfer RNA isolated from host cells. (1971) (30)
- Circular dichroism and ordered structure of bisnucleoside oligophosphates and their Zn2+ and Mg2+ complexes. (1983) (30)
- Growth of cultured cells from patients with Hodgkin's disease and transplantation into nude mice. (1977) (27)
- Amino-acid acceptor activity of the "70S-associated" 4S RNA from avian myeloblastosis virus. (1973) (25)
- Purification of valine transfer ribonucleic acid by combined chromatographic and chemical procedures. (1961) (24)
- Historical Aspects of Protein Synthesis * (1979) (23)
- Some optical properties of diadenosine-5'-phosphates. (1969) (23)
- Thiosine-resistant mutants of Escherichia coli K-12 with growth-medium-dependent lysyl-tRNA synthetase activity.II. Evidence for an altered lysyl-tRNA synthetase. (1972) (22)
- 5',5'''-P1, P4 diadenosine tetraphosphate (Ap4A): a putative initiator of DNA replication. (1985) (22)
- Some physical properties of lysyl and arginyl-transfer RNA synthetases of Escherichia coli B. (1969) (22)
- The use of labeled amino acids in the study of the protein metabolism of normal and malignant tissues: a review. (1950) (22)
- History of antisense oligonucleotides. (1996) (21)
- Evidence that the polyadenylic acid segment of "35S" RNA of avian myeloblastosis virus is located at the 3'-OH terminus. (1973) (21)
- ON THE AMINOACYL-RNA SYNTHETASE RECOGNITION SITES OF YEAST AND E. COLI TRANSFER RNA. (1963) (20)
- THE TOXIC FACTORS IN EXERIMENTAL TRAUMATIC SHOCK. VI. THE TOXIC INFLUENCE OF THE BACTERIAL FLORA, PARTICULARLY CLOSTRIDIUM WELCHII, IN EXUDATES OF ISCHEMIC MUSCLE. (1945) (20)
- PHYSIOLOGIC ACTION OF CLOSTRIDIUM WELCHII (TYPE A) TOXINS IN DOGS. (1947) (19)
- Phosphoramidate, Phosphorothioate, and Methylphosphonate Analogs of Oligodeoxynucleotide : Inhibitors of Replication of Human Immunodeficiency Virus (1989) (19)
- Antithrombotic effect of beta,beta'-monochloromethylene diadenosine 5',5"'-P1,P4-tetraphosphate. (1992) (18)
- Relationship of the first step in protein synthesis to ppGpp: formation of A(5')ppp(5')Gpp. (1975) (18)
- Plasmodium falciparum: effect of chemical structure on efficacy and specificity of antisense oligonucleotides against malaria in vitro. (1998) (18)
- Oligonucleotides with rapid turnover of the phosphate groups occur endogenously in eukaryotic cells. (1987) (17)
- The 3'-terminal nucleosides of the high molecular weight RNA of avian myeloblastosis virus. (1972) (17)
- Near-infrared fluorescent oligodeoxyribonucleotide reporters for sensing NF-kappaB DNA interactions in vitro. (2008) (17)
- PHYSIOLOGIC ACTION OF CLOSTRIDIUM OEDEMATIENS (NOVYI) TOXIN IN DOGS. (1947) (17)
- The biochemistry of neoplastic tissue. (1952) (16)
- Activity of catheptic enzymes in p-dimethylaminoazobenzene hepatomas. (1947) (16)
- Summary of symposium on transfer RNA and transfer RNA modification in differentiation and neoplasia. (1971) (15)
- Isolation of valyl-RNA of a high degree of purity. (1962) (15)
- THE TOXIC FACTORS IN EXPERIMENTAL TRAUMATIC SHOCK. II. STUDIES ON ELECTROLYTE AND WATER BALANCE IN SHOCK. (1945) (15)
- Diadenosine 5',5'''-p1,p4-tetraphosphate deficiency in blood platelets of the Chédiak-Higashi syndrome. (1985) (15)
- T1 ribonuclease inhibition of polyuridylic acid-stimulated polyphenylalanine synthesis. (1963) (15)
- Aspects of the kinetic properties of lysyl-tRNA synthetase from Escherichia coli, strain B. (1970) (15)
- Effect of Bromination on the Biological Activities of Transfer RNA of Escherichia coli (1964) (15)
- An in vivo effect of the metabolites L-alanine and glycyl-L-leucine on the properties of lysyl-tRNA synthetase from Escherichia coli K-12. I. Influence on subunit composition and molecular weight distribution. (1976) (14)
- Biological Synthesis of Radioactive Silk. (1949) (14)
- Aminoacyl-tRNA synthetases catalyze AMP----ADP----ATP exchange reactions, indicating labile covalent enzyme-amino-acid intermediates. (1987) (14)
- Conjugates of minor groove DNA binders with oligodeoxynucleotides: synthesis and properties. (1996) (13)
- THE TOXIC FACTORS IN EXPERIMENTAL TRAUMATIC SHOCK. I. PHYSIOLOGIC EFFECTS OF MUSCLE LIGATION IN THE DOG. (1945) (13)
- MODIFICATION OF AMINO ACID ACCEPTANCE AND TRANSFER CAPACITY OF RNA IN THE PRESENCE OF ORGANIC SOLVENTS. (1965) (13)
- The effect of sex hormones on hepatic and renal lesions induced in rats by a choline-deficient diet. (1951) (13)
- Increased incorporation of adenosine into adenine nucleotide pools in serum-deprived mammalian cells. (1978) (12)
- 99mTc-labeled nucleotides as tumor-seeking radiodiagnostic agents. (1984) (12)
- THE TOXIC FACTORS IN EXPERIMENTAL TRAUMATIC SHOCK. IV. THE EFFECTS OF THE INTRAVENOUS INJECTION OF THE EFFUSION FROM ISCHEMIC MUSCLE. (1945) (12)
- Protection of Animals Against CI. welchii (Type A) Toxin by Injection of Certain Purified Lipids.∗ † (1945) (12)
- Chemical modification of aminoacyl ligases and the effect on formation of aminoacyl-tRNA. (1967) (12)
- Optical rotatory dispersion of E. coli sRNA in the far ultraviolet region. (1965) (12)
- Conformational differences among purified samples of transfer RNA from yeast. (1966) (11)
- THE TOXIC FACTORS IN EXPERIMENTAL TRAUMATIC SHOCK. V. CHEMICAL AND ENZYMATIC PROPERTIES OF MUSCLE EXUDATE. (1945) (11)
- An antigen in Hodgkin's disease tissue cultures: fluorescent antibody studies. (1974) (11)
- Studies on the Mechanism of Protein Synthesis (1958) (11)
- Synthesis and Anti‐HIV Activity of Oligoribonucleotides and Their Phosphorothioate Analogs (1992) (11)
- From protein synthesis to genetic insertion. (2005) (11)
- In vitro incorporation of C14-DL-leucine into normal and leukemic white cells. (1957) (10)
- A Novel Thymidine Phosphoramidite Synthon for Incorporation of Internucleoside Phosphate Linkers During Automated Oligodeoxynucleotide Synthesis (2008) (10)
- The machinery of protein synthesis (1984) (10)
- Minor base composition of "70S-associated" 4S RNA from avian myeloblastosis virus. (1973) (9)
- THE TOXIC FACTORS IN EXPERIMENTAL TRAUMATIC SHOCK. III. SHOCK ACCOMPANYING MUSCLE ISCHEMIA AND LOSS OF VASCULAR FLUID. (1945) (9)
- Proton magnetic resonance investigation of interactions between L‐tryptophan and dinucleoside phosphates at low pD (1977) (9)
- A sensitive micro assay for inorganic pyrophosphatase. (1970) (8)
- Electron microscopy of hodgkin's disease tissue cultures (1979) (7)
- THE DISTRIBUTION OF INJECTED ORGANIC DISELENIDES IN TISSUES OF TUMOR-BEARIN G ANIMALS (1941) (7)
- Diagnosis of storage pool deficiency by determination of diadenosine 5', 5'''-P1,P4-tetraphosphate in whole blood. (1986) (7)
- Chromatographic and electrophoretic analysis of an antigen in Hodgkin's disease tissue cultures. (1977) (7)
- Mutation of chloroplasts in Ageratum, following treatment with 5-bromodeoxyuridine. (1967) (7)
- A tumor antigen in tissue cultures derived from patients with Hodgkin's disease. (1973) (7)
- Covalent modification of phenylalanyl-tRNA synthetase with phenylalanine during the amino acid activation reaction catalyzed by the enzyme. (1985) (6)
- A manometric method for determining the kinetics of an enzymatic hydrolysis of peptides. (1947) (6)
- An antigen in Hodgkin's disease tissue cultures: radioiodine-labeled antibody studies. (1974) (6)
- MICROPHOTOMETRIC DETERMINATION OF THE RATE OF ENZYMATIC PROTEOLYSIS (1945) (6)
- Unsettled questions in the field of protein synthesis. (1962) (5)
- A comparison of activators of proteolytic enzymes and peptidases in normal rat livers and hepatomas. (1949) (4)
- Inhibition of in vitro transcription by oligodeoxynucleotides. (1994) (4)
- The toxic factors in experimental traumatic shock; the toxic influence of the bacterial flora, particularly Clostridium welchii, in exudates of ischemic muscle. (1945) (4)
- Analysis of oncornavirus RNA subunits by electron microscopy. (1975) (3)
- Solid phase synthesis of oligonucleotides carrying puromycin at 3′-terminal (1993) (3)
- DISTRIBUTION OF CATHEPTIC ENZYMES IN THE HOG KIDNEY (1945) (3)
- A new chemical procedure for 32P-labeling of ribonucleic acids at their 5'-ends after isolation. (1975) (3)
- Oligodeoxynucleotide hybridization inhibition of HIV and influenza virus. (1991) (3)
- TOXIC FACTORS IN EXPERIMENTAL TRAUMATIC SHOCK (2)
- Lack of Carcinoǵenic Potency of Sulfanilamide and Prontosil Soluble in Mice (1939) (2)
- Demyelination by means of enzymes. (1949) (2)
- Action of osmium tetroxide on amino acid-transfer ribonucleic acid: correlations between the genetic code and the sensitivity of acceptor activity. (1966) (2)
- PARTIAL PURIFICATION OF TRANSFER RNA * (1960) (2)
- The mechanism of protein synthesis and its possible alteration in the presence of oncogenic RNA viruses. (1966) (2)
- [89] Partial purification of amino acid specific soluble RNA's by means of a chemical modification of the terminal ribose of sRNA☆ (1967) (2)
- PROTEIN SYNTHESIS: EARLY WAVES AND RECENT RIPPLES (1976) (2)
- The mechanism of amino acid activation: the work of Mahlon Hoagland. 1956. (2009) (1)
- Priming of DNA synthesis by diadenosine 5',5"'-P ,P4- tetraphosphate with a double-stranded octadecamer (1)
- OLIGONUCLEOTIDES AND GROWTH REGULATION (1979) (1)
- THE INFLUENCE OF ANTITOXIN UPON THE ACTION OF CLOSTRIDIUM OEDEMATIENS TOXIN IN THE HEART-LUNG PREPARATION OF THE DOG. (1947) (1)
- [18] Modification of tRNA's by bromination (1971) (1)
- Similarities in ATP-binding domain between E. coli tyrosyl-tRNA synthetase and human estrogen receptor. (1989) (1)
- Use of Drugs Targeted to Inhibit Different Stages of the HIV Life Cycle in the Treatment of AIDS (1992) (1)
- Carbon-14 and the Development of In Vitro Protein Synthesis Research (2003) (0)
- Multiple myeloma. (1949) (0)
- Early steps in protein synthesis and their regulation: a background study related to the biological effects of radiation. Progress report, July 1, 1974--June 30, 1975 (1975) (0)
- Early steps in protein synthesis and their regulation: a background study related to the biological effects of radiation. Progress report, July 1, 1973--June 30, 1974 (1974) (0)
- A New Chemical Procedure for 32P-Labeli Their 5'-Ends after Isolation (2016) (0)
- Joseph Charles Aub 1890-1973. (1974) (0)
- Intermediate reactions in protein biosynthesis. 1957. (1989) (0)
- Protein synthesis and its regulation: a background study related to the biological effects of radiation. Progress report, July 1, 1976--August 31, 1977 (1977) (0)
- A New Chemical Procedure for 32 P-Labeling of Ribonucleic Acids at Their 5 '-Ends after Isolation ( 5 '-terminus / 35 S RNA of avian myeloblastosis virus / nonaqueous media ) (0)
- The toxic factors in experimental traumatic shock; chemical and enzymatic properties of muscle exudate. (1945) (0)
- AN ENZYMATIC MECHANISM FOR LINKING AMINO ACIDS TO RNA* (2004) (0)
- The machinenj of protein synthesis (1984) (0)
- TISSUE CULTURE STUDIES IN HODGKIN ' S DISEASE (2003) (0)
- Studies on in vitro metabolism of the rat hepatoma. (1952) (0)
- Foreword: Looking to the Future (2005) (0)
- Concerning the Recognition Reaction and Transfer RNA in Protein Synthesis (1967) (0)
- Method for site-specific modification of rna and production of polypeptides encoded thereby (1991) (0)
- THE TOXIC FACTORS IN EXPERIMENTAL TRAUMATICSHOCK (0)
- WKB edge-effect corrections to numerical wave functions for asymmetric potentials (1987) (0)
- 710 Cancer Research The transfer of some substance or substances through the medium of body tissues (0)
- Early steps in protein synthesis and their regulation: a background study related to the biological effects of radiation. Progress report, July 1, 1975--June 30, 1976 (1976) (0)
- Increased incorporation of adenosi in serum-deprived mammalian cell (growth regulation) (2016) (0)
- Members Elected in 2006 (2006) (0)
- Intermediate reactions in amino acid incorporation in normal and neoplastic tissues. (1960) (0)
- Antisense oligonucleotide analogues as therapeutic agents. (1990) (0)
- HISTORICAL BACKGROUND ON DIADENOSINE 5′,5″′-P1,P4-TETRAPHOSPHATE (AP4A) AND CURRENT DEVELOPMENTS (1979) (0)
- TRANSMUISSIBLE VARIATIONS IN \ THE CYTOPLASM ITVIITHiNJ \ SPECIES OF HIGHER PLANTS * By (0)
- Resolution of the diadenosine 5 ' , 5 " '-Pl , P 4-tetraphosphate binding subunit from a multiprotein form of HeLa cell DNA polymerase a ( DNA replication ) (0)
- A 11 Patent Number : 5 , 637 , 459 45 ) Date of Patent : Jun . 10 , 1997 (2017) (0)
- AN INVESTIGATION ON THE MECHANISMS AND REGULATIONS OF NUCLEIC ACID AND PROTEIN SYNTHESIS, AND THEIR POSSIBLE RELATIONSHIP TO RADIATION DAMAGE. Progress Report, September 1, 1964-August 31, 1965 (1965) (0)
- Minor base changes in transfer ribonucleic acid in avian myeloblastosis virus. (1973) (0)
- Regulation of Growth, and Its Relation to Cancer. (1967) (0)
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