Paula Cohen
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British-American geneticist, professor and Associate Vice Provost for Life Sciences at Cornell University
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Paula Cohenbiology Degrees
Biology
#15073
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Genetics
#1859
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#1975
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Biology
Why Is Paula Cohen Influential?
(Suggest an Edit or Addition)According to Wikipedia, Paula Elaine Cohen is a British-American geneticist who is a professor and Associate Vice Provost for Life Sciences at Cornell University. Her research considers DNA repair mechanisms and the regulation of crossing over during mammalian meiosis. She was awarded the National Down Syndrome Society Charles J. Epstein Down Syndrome Research Award in 2004 and elected Fellow of the American Association for the Advancement of Science in 2021.
Paula Cohen's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Meiotic Pachytene Arrest in MLH1-Deficient Mice (1996) (578)
- MutS homolog 4 localization to meiotic chromosomes is required for chromosome pairing during meiosis in male and female mice. (2000) (444)
- Mammalian MutS homologue 5 is required for chromosome pairing in meiosis (1999) (391)
- Mutation in the Mismatch Repair Gene Msh6 Causes Cancer Susceptibility (1997) (378)
- Meiotic arrest and aneuploidy in MLH3-deficient mice (2002) (363)
- The time course and chromosomal localization of recombination-related proteins at meiosis in the mouse are compatible with models that can resolve the early DNA-DNA interactions without reciprocal recombination. (2002) (342)
- Inactivation of Exonuclease 1 in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterility. (2003) (323)
- Control of Meiotic Crossovers: From Double-Strand Break Formation to Designation. (2016) (237)
- RNF212 is a dosage-sensitive regulator of crossing-over during mammalian meiosis (2013) (217)
- Essential Role of Fkbp6 in Male Fertility and Homologous Chromosome Pairing in Meiosis (2003) (201)
- Not all germ cells are created equal: aspects of sexual dimorphism in mammalian meiosis. (2005) (190)
- MUS81 Generates a Subset of MLH1-MLH3–Independent Crossovers in Mammalian Meiosis (2008) (178)
- Genetic Recombination Is Targeted towards Gene Promoter Regions in Dogs (2013) (177)
- Genetic analysis of chromosome pairing, recombination, and cell cycle control during first meiotic prophase in mammals. (2006) (163)
- Mismatch Repair Genes Mlh1 and Mlh3 Modify CAG Instability in Huntington's Disease Mice: Genome-Wide and Candidate Approaches (2013) (163)
- Extreme heterogeneity in the molecular events leading to the establishment of chiasmata during meiosis i in human oocytes. (2005) (153)
- Antagonistic roles of ubiquitin ligase HEI10 and SUMO ligase RNF212 regulate meiotic recombination (2014) (147)
- Absence of colony stimulating factor-1 in osteopetrotic (csfmop/csfmop) mice disrupts estrous cycles and ovulation. (1997) (143)
- Macrophages: important accessory cells for reproductive function (1999) (137)
- Absence of colony-stimulating factor-1 in osteopetrotic (csfmop/csfmop) mice results in male fertility defects. (1996) (134)
- Localization of MMR proteins on meiotic chromosomes in mice indicates distinct functions during prophase I (2005) (119)
- Regulation of meiotic recombination and prophase I progression in mammals (2001) (117)
- Control of Spermatogenesis in Mice by the Cyclin D-Dependent Kinase Inhibitors p18Ink4c and p19Ink4d (2001) (117)
- Ubiquitylated PCNA plays a role in somatic hypermutation and class-switch recombination and is required for meiotic progression (2008) (104)
- AGO4 regulates entry into meiosis and influences silencing of sex chromosomes in the male mouse germline. (2012) (93)
- Colony-stimulating factor-1 plays a major role in the development of reproductive function in male mice. (1997) (88)
- Chromosome Cohesion Established by Rec8-Cohesin in Fetal Oocytes Is Maintained without Detectable Turnover in Oocytes Arrested for Months in Mice (2016) (81)
- Mammalian BLM helicase is critical for integrating multiple pathways of meiotic recombination (2010) (73)
- Mismatch repair proteins, meiosis, and mice: understanding the complexities of mammalian meiosis. (2004) (72)
- SFMBT1 functions with LSD1 to regulate expression of canonical histone genes and chromatin-related factors. (2013) (71)
- Mammalian BTBD12 (SLX4) Protects against Genomic Instability during Mammalian Spermatogenesis (2011) (69)
- Mammalian CNTD1 is critical for meiotic crossover maturation and deselection of excess precrossover sites (2014) (67)
- Colony-stimulating factor 1 regulation of neuroendocrine pathways that control gonadal function in mice. (2002) (65)
- Ovol1 regulates meiotic pachytene progression during spermatogenesis by repressing Id2 expression (2005) (63)
- Dynamic transcriptome profiles within spermatogonial and spermatocyte populations during postnatal testis maturation revealed by single-cell sequencing (2018) (58)
- The roles of microRNAs and siRNAs in mammalian spermatogenesis (2016) (55)
- Conditional Inactivation of the DNA Damage Response Gene Hus1 in Mouse Testis Reveals Separable Roles for Components of the RAD9-RAD1-HUS1 Complex in Meiotic Chromosome Maintenance (2013) (55)
- Silastic implants for delivery of oestradiol to mice. (1993) (54)
- Distinct Functions of MLH3 at Recombination Hot Spots in the Mouse (2008) (54)
- Effect of the colony-stimulating factor-1 null mutation, osteopetrotic (csfm(op)), on the distribution of macrophages in the male mouse reproductive tract. (1997) (48)
- Distinct effects of the recurrent Mlh1G67R mutation on MMR functions, cancer, and meiosis (2008) (45)
- Comparative Analysis of Meiotic Progression in Female Mice Bearing Mutations in Genes of the DNA Mismatch Repair Pathway1 (2008) (39)
- Dgcr8 and Dicer are essential for sex chromosome integrity during meiosis in males (2015) (38)
- Silastic implants for delivering physiological concentrations of progesterone to mice. (1994) (32)
- Normal sexual function in male mice lacking a functional type I interleukin-1 (IL-1) receptor. (1998) (32)
- Cohesin Removal along the Chromosome Arms during the First Meiotic Division Depends on a NEK1-PP1γ-WAPL Axis in the Mouse. (2016) (28)
- FancJ (Brip1) loss-of-function allele results in spermatogonial cell depletion during embryogenesis and altered processing of crossover sites during meiotic prophase I in mice (2016) (27)
- A role for Mlh3 in somatic hypermutation. (2006) (27)
- Analysis of meiotic prophase I in live mouse spermatocytes (2008) (24)
- Predicting Gene Networks in Human Oocyte Meiosis (2010) (21)
- The minimum requirements for oestradiol to induce uterine sensitivity for implantation and decidualization in mice. (1995) (20)
- A mutation in the endonuclease domain of mouse MLH3 reveals novel roles for MutLγ during crossover formation in meiotic prophase I (2019) (20)
- Transcriptome profiling of the developing male germ line identifies the miR-29 family as a global regulator during meiosis (2017) (19)
- NEK1 Facilitates Cohesin Removal during Mammalian Spermatogenesis (2011) (16)
- Small RNAs and RNAi pathways in meiotic prophase I (2007) (14)
- NIMA-related kinase 1 (NEK1) regulates meiosis I spindle assembly by altering the balance between α-Adducin and Myosin X (2017) (13)
- Mutation of the ATPase Domain of MutS Homolog-5 (MSH5) Reveals a Requirement for a Functional MutSγ Complex for All Crossovers in Mammalian Meiosis (2019) (12)
- Double trouble in human aneuploidy (2015) (9)
- Cyclin N-Terminal Domain-Containing-1 Coordinates Meiotic Crossover Formation with Cell-Cycle Progression in a Cyclin-Independent Manner (2019) (8)
- Dgcr8 and Dicer are essential for sex chromosome integrity during meiosis in males (2015) (7)
- Somatic CAG expansion in Huntington's disease is dependent on the MLH3 endonuclease domain, which can be excluded via splice redirection (2021) (6)
- Characterization of telomeric repeat-containing RNA (TERRA) localization and protein interactions in primordial germ cells of the mouse†. (2018) (6)
- Use of the Osteopetrotic Mouse for Studying Macrophages in the Reproductive Tract (1994) (6)
- Genetic dissection of the RNA polymerase II transcription cycle (2021) (6)
- Studying recombination in mouse oocytes. (2013) (6)
- FancJ (Brip1) loss-of-function allele results in spermatogonial cell depletion during embryogenesis and altered processing of crossover sites during meiotic prophase I in mice (2015) (4)
- Special issue on “recent advances in meiotic chromosome structure, recombination and segregation” (2016) (4)
- Phosphoproteomics of ATR signaling in mouse testes (2022) (3)
- Role of EXO1 nuclease activity in genome maintenance, the immune response and tumor suppression in Exo1D173A mice (2021) (3)
- Chapter 1 – Mammalian Meiosis (2015) (3)
- Phosphoproteomics of ATR Signaling in Prophase I of Mouse Meiosis (2021) (1)
- Mutation Of MLH3 Endonuclease Motif Reveals Integration Between Crossover Pathways In Mammalian Meiosis (2019) (1)
- NIMA-related kinase 1 (NEK1) regulates the localization and phosphorylation of α-Adducin (ADD1) and Myosin X (MYO10) during meiosis (2017) (1)
- Chromosome Pairing in Meiosis Essential Role of Fkbp 6 in Male Fertility and Homologous (2014) (0)
- Stuart B. Moss: a leader and advocate for the reproductive biology community (2021) (0)
- Biology and Pathology of the Oocyte: Gene networks in oocyte meiosis (2013) (0)
- Meiotic gene transcription programs are mediated by A-MYB and BRDT-dependent RNA polymerase II pause release during mammalian prophase I (2022) (0)
- A-MYB and BRDT-dependent RNA Polymerase II pause release orchestrates transcriptional regulation in mammalian meiosis (2023) (0)
- Mammalian CNTD 1 is critical for meiotic crossover maturation (2014) (0)
- Non‐human primates exhibit errors in meiosis I (2012) (0)
- Postnatal oogenesis leads to an exceptionally large ovarian reserve in naked mole-rats (2023) (0)
- Special Announcement (1995) (0)
- Cohesin Removal along th e Chromosome Arms during the First Meiotic Division Depends on a NEK 1-PP 1 g-WAPL Axis in the Mouse Graphical (2016) (0)
- Characterization of Telomeric Repeat-Containing RNA (TERRA) localization and protein interactions in Primordial Germ Cells of the mouse (2018) (0)
- Somatic CAG expansion in Huntington’s disease is dependent on the MLH3 endonuclease domain, which can be excluded via MLH3 splice redirection to suppress expansion (2020) (0)
- Macrophages: Trophic roles in reproduction (1996) (0)
- Generation and properties of mouse oocytes that lack N-acetylglucosaminyltransferase I (2002) (0)
- Small RNAs and their protein partners in animal meiosis. (2023) (0)
- Initial investigation of ubiquitination pathway in mammalian meiosis (2010) (0)
- Multiple 9-1-1 complexes promote homolog synapsis, DSB repair, and ATR signaling during mammalian meiosis (2021) (0)
- Repair Proteins in Meiosis (2004) (0)
- The Birth of an Alternatively Spliced Exon : 3 Splice-Site Selection in Alu Exons (2003) (0)
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