Pauline Johnson
#35,640
Most Influential Person Now
English immunologist and microbiologist
Pauline Johnson 's AcademicInfluence.com Rankings
Pauline Johnson biology Degrees
Biology
#1122
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#1922
Historical Rank
Microbiology
#99
World Rank
#121
Historical Rank
Immunology
#1056
World Rank
#1082
Historical Rank
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Biology
Pauline Johnson 's Degrees
- Bachelors Microbiology University of Oxford
- PhD Microbiology Imperial College London
Why Is Pauline Johnson Influential?
(Suggest an Edit or Addition)According to Wikipedia, Pauline Johnson is an English immunologist and microbiologist at the University of British Columbia. Her research focuses on innate and adaptive immune mechanisms — in particular, the mobility of proteins in membranes, lymphocyte cell surface molecules, T cell signalling, leukocyte adhesion, and macrophages in lung inflammation.
Pauline Johnson 's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling (2001) (576)
- Galectin-3 and Galectin-1 Bind Distinct Cell Surface Glycoprotein Receptors to Induce T Cell Death1 (2006) (293)
- Role of CD44 and Hyaluronan in Neutrophil Recruitment1 (2004) (184)
- CD44 and its role in inflammation and inflammatory diseases. (2009) (160)
- Y-box binding protein-1 induces the expression of CD44 and CD49f leading to enhanced self-renewal, mammosphere growth, and drug resistance. (2010) (160)
- Host Defense Peptide LL-37 Selectively Reduces Proinflammatory Macrophage Responses (2011) (145)
- Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement (2018) (137)
- TNF-α Induction of CD44-Mediated Leukocyte Adhesion by Sulfation (1998) (133)
- The Where, When, How, and Why of Hyaluronan Binding by Immune Cells (2015) (120)
- Association of 75/80-kDa Phosphoproteins and the Tyrosine Kinases Lyn, Fyn, and Lck with the B Cell Molecule CD20 (1995) (118)
- Characterization of Recombinant CD45 Cytoplasmic Domain Proteins (1998) (90)
- Use of CD44 by CD4+ Th1 and Th2 lymphocytes to roll and adhere. (2006) (85)
- Temporal stability of the mouse gut microbiota in relation to innate and adaptive immunity. (2013) (81)
- The Suv39H1 methyltransferase inhibitor chaetocin causes induction of integrated HIV‐1 without producing a T cell response (2011) (77)
- CD44-initiated Cell Spreading Induces Pyk2 Phosphorylation, Is Mediated by Src Family Kinases, and Is Negatively Regulated by CD45* (2001) (65)
- Demonstration of a Direct Interaction between p56 and the Cytoplasmic Domain of CD45 in Vitro(*) (1996) (62)
- Endotoxin free hyaluronan and hyaluronan fragments do not stimulate TNF-α, interleukin-12 or upregulate co-stimulatory molecules in dendritic cells or macrophages (2016) (62)
- Role of Sulfation in CD44-Mediated Hyaluronan Binding Induced by Inflammatory Mediators in Human CD14+ Peripheral Blood Monocytes1 (2001) (62)
- Hyaluronan and Its Interactions With Immune Cells in the Healthy and Inflamed Lung (2018) (57)
- Hyaluronan Induces Cell Death in Activated T Cells through CD441 (2008) (56)
- Protective Effect of Killed Trypanosome Vaccines with Incorporated Adjuvants (1963) (56)
- Differential Use of Chondroitin Sulfate to Regulate Hyaluronan Binding by Receptor CD44 in Inflammatory and Interleukin 4-activated Macrophages* (2011) (53)
- Striking similarities between antigen receptor J pieces and sequence in the second chain of the murine CD8 antigen (1986) (49)
- Differential expression of the alternatively spliced exons of murine CD45 in Th1 and Th2 cell clones (1991) (49)
- TNF-alpha increases the carbohydrate sulfation of CD44: induction of 6-sulfo N-acetyl lactosamine on N- and O-linked glycans. (2002) (43)
- Regulation of hyaluronan binding by F-actin and colocalization of CD44 and phosphorylated ezrin/radixin/moesin (ERM) proteins in myeloid cells. (2005) (43)
- Arginase activity in alternatively activated macrophages protects PI3Kp110δ deficient mice from dextran sodium sulfate induced intestinal inflammation (2014) (39)
- Characterization of the Interaction between CD45 and CD45-AP (*) (1995) (39)
- CD45 Regulates TLR-Induced Proinflammatory Cytokine and IFN-β Secretion in Dendritic Cells1 (2008) (35)
- Apoptosis Mediated Through CD45 Is Independent of Its Phosphatase Activity and Association with Leukocyte Phosphatase-Associated Phosphoprotein1 (2002) (27)
- CD45-Mediated Fodrin Cleavage during Galectin-1 T Cell Death Promotes Phagocytic Clearance of Dying Cells1 (2009) (26)
- Hyaluronan binding identifies the most proliferative activated and memory T cells (2011) (25)
- CD44 interacts directly with Lck in a zinc-dependent manner. (2010) (25)
- Differential Function of PTPα and PTPα Y789F in T Cells and Regulation of PTPα Phosphorylation at Tyr-789 by CD45* (2007) (22)
- CD45 Regulates Migration, Proliferation, and Progression of Double Negative 1 Thymocytes (2010) (22)
- Immunoglobulin-Related Structures Associated with Vertebrate Cell Surfaces (1988) (21)
- Expression of N-acetylglucosamine 6-O-sulfotransferases (GlcNAc6STs)-1 and -4 in human monocytes: GlcNAc6ST-1 is implicated in the generation of the 6-sulfo N-acetyllactosamine/Lewis x epitope on CD44 and is induced by TNF-alpha. (2005) (21)
- CD45 phosphatase is crucial for human and murine acute myeloid leukemia maintenance through its localization in lipid rafts (2016) (21)
- CD45 Down-Regulates Lck-Mediated CD44 Signaling and Modulates Actin Rearrangement in T Cells1 (2008) (21)
- Chimeric CD4/CD44 molecules associate with CD44 via the transmembrane region and reduce hyaluronan binding in T cell lines (1998) (20)
- Chondroitin sulfate addition to CD44H negatively regulates hyaluronan binding. (2005) (20)
- Tyrosine phosphorylation in immune cells: direct and indirect effects on toll-like receptor-induced proinflammatory cytokine production. (2009) (19)
- CD44-mediated elongated T cell spreading requires Pyk2 activation by Src family kinases, extracellular calcium, phospholipase C and phosphatidylinositol-3 kinase. (2011) (18)
- Hyaluronan Binding Identifies a Functionally Distinct Alveolar Macrophage–like Population in Bone Marrow–Derived Dendritic Cell Cultures (2015) (18)
- Expression of CD45 Lacking the Catalytic Protein Tyrosine Phosphatase Domain Modulates Lck Phosphorylation and T Cell Activation* (2005) (18)
- Subdomain X of the Kinase Domain of Lck Binds CD45 and Facilitates Dephosphorylation* (2004) (18)
- CD44 Loss Disrupts Lung Lipid Surfactant Homeostasis and Exacerbates Oxidized Lipid-Induced Lung Inflammation (2020) (16)
- CD44-mediated hyaluronan binding marks proliferating hematopoietic progenitor cells and promotes bone marrow engraftment (2018) (14)
- The amoebicidal activity and toxicity of natural emetine, (±)-2-dehydroemetine and (−)-2-dehydroemetine (1968) (14)
- A human homolog of the mouse CD8 molecule, Lyt-3: genomic sequence and expression (2004) (13)
- The noncatalytic domains of Lck regulate its dephosphorylation by CD45. (2003) (13)
- ATG Genes Influence the Virulence of Cryptococcus neoformans through Contributions beyond Core Autophagy Functions (2018) (12)
- H2-M3-Restricted T Cells Participate in the Priming of Antigen-Specific CD4+ T Cells1 (2006) (12)
- Differential function of PTPalpha and PTPalpha Y789F in T cells and regulation of PTPalpha phosphorylation at Tyr-789 by CD45. (2007) (12)
- A cell death pathway induced by antibody-mediated cross-linking of CD45 on lymphocytes. (2003) (12)
- Regulation of CD71+TER119+ erythroid progenitor cells by CD45. (2020) (9)
- Splenic erythroid progenitors decrease TNF‐α production by macrophages and reduce systemic inflammation in a mouse model of T cell‐induced colitis (2020) (8)
- Purification of Membrane Glycoproteins with Monoclonal Antibody Affinity Columns (1985) (7)
- Generation and Identification of GM-CSF Derived Alveolar-like Macrophages and Dendritic Cells From Mouse Bone Marrow. (2016) (7)
- Use of CD 44 by CD 4 Th 1 and Th 2 lymphocytes to roll and adhere (2006) (7)
- Innate Immune Cell CD45 Regulates Lymphopenia-Induced T Cell Proliferation (2014) (7)
- CD8B, the human equivalent of the mouse Ly-3 gene is localized on chromosome 2 (2004) (6)
- Detection of restricted isoform expression and tyrosine phosphatase activity of CD45 in murine dendritic cells (1995) (6)
- The immunophilin protein FKBPL and its peptide derivatives are novel regulators of vascular integrity and inflammation via NF-κB signaling (2021) (5)
- Hyaluronan‐binding by CD44 reduces the memory potential of activated murine CD8 T cells (2018) (4)
- CD 45 Down-Regulates Lck-Mediated CD 44 Signaling and Modulates Actin Rearrangement in T Cells 1 (2008) (2)
- Clearance of Dying Cells Galectin-1 T Cell Death Promotes Phagocytic CD 45-Mediated Fodrin Cleavage during (2009) (2)
- Inflammation-induced metastatic colonization of the lung is facilitated by HGF-secreting monocyte-derived macrophages. (2021) (2)
- Dendritic Cell Cultures Derived - Population in Bone Marrow like - Distinct Alveolar Macrophage Hyaluronan Binding Identifies a Functionally (2015) (0)
- Human Hybridomas and Monoclonal Antibodies (1986) (0)
- Secretion in Dendritic Cells Proinflammatory Cytokine and IFN-CD45 Regulates TLR-Induced (2008) (0)
- The tyrosine phosphatase CD45 regulates lymphopenia-induced T cell proliferation (47.15) (2012) (0)
- T Cells through CD44 Hyaluronan Induces Cell Death in Activated (0)
- ResponsesReduces Proinflammatory Macrophage Host Defense Peptide LL-37 Selectively (2011) (0)
- Phosphatase-Associated Phosphoprotein Association with Leukocyte Independent of Its Phosphatase Activity and Apoptosis Mediated Through CD45 Is (2002) (0)
- Purification and sequence of the rat CDS antigen, a cytotoxic T-cell marker (1986) (0)
- Inflammation-Induced Metastatic Colonization of the Lung Is Facilitated by Hepatocyte Growth Factor-Secreting Monocyte-Derived Macrophages (2021) (0)
- RNA sequencing and lipidomic analysis of alveolar macrophages from normal and CD44 deficient mice (2019) (0)
- Rearrangement in T Cells Signaling and Modulates Actin CD45 Down-Regulates Lck-Mediated CD44 (2013) (0)
- Research Groups Infection , Inflammation and Immunity ( I 3 ) (2016) (0)
- Peripheral Blood Monocytes + Inflammatory Mediators in Human CD 14 Hyaluronan Binding Induced by Role of Sulfation in CD 44-Mediated (2001) (0)
- Abstract 978: Monocyte-derived macrophages contribute to the inflammation-induced survival of experimental micrometastases in the lung (2020) (0)
- Transmembrane Pickets Connect Cyto- and Exo-skeletons Forming Barriers to Receptor Engagement (2018) (0)
- Recruitmentof CD44 and Hyaluronan in Neutrophil (2012) (0)
- HOW DENDRITIC CELL CD45 REGULATES THE OUTCOME OF AN IMMUNE CHALLENGE: 3036 (2010) (0)
- Determinants of phagocytic receptor mobility: cytoskeletal picket fences and the pericellular glycocalyx coat. (2017) (0)
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Pauline Johnson is affiliated with the following schools:
