Pedro Cuatrecasas
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Pedro Cuatrecasas's Degrees
- Doctorate Medicine University of Barcelona
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(Suggest an Edit or Addition)Pedro Cuatrecasas's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Protein purification by affinity chromatography. Derivatizations of agarose and polyacrylamide beads. (1970) (2056)
- A simplified method for cyanogen bromide activation of agarose for affinity chromatography. (1974) (1673)
- [31] Affinity chromatography (1971) (1263)
- Selective enzyme purification by affinity chromatography. (1968) (914)
- Immunohistochemical localization of enkephalin in rat brain and spinal cord (1978) (788)
- Multiple opiate receptors. Enkephalins and morphine bind to receptors of different specificity. (1979) (615)
- Gangliosides and membrane receptors for cholera toxin. (1973) (490)
- Interaction of Vibrio cholerae enterotoxin with cell membranes. (1973) (451)
- Membrane receptors and hormone action. (1976) (411)
- Multiple opiate receptors: different regional distribution in the brain and differential binding of opiates and opioid peptides. (1979) (398)
- Adsorbents for affinity chromatography. Use of N-hydroxysuccinimide esters of agarose. (1972) (396)
- Specific nonopiate receptors for beta-endorphin. (1979) (393)
- Mitogen-activated Protein Kinase Kinase Inhibition Does Not Block the Stimulation of Glucose Utilization by Insulin (*) (1995) (393)
- Monoclonal antibodies to receptors for insulin and somatomedin-C. (1983) (375)
- A model for intracellular translocation of protein kinase C involving synergism between Ca2+ and phorbol esters (1985) (372)
- Insulin--receptor interactions in adipose tissue cells: direct measurement and properties. (1971) (347)
- Insulin-stimulated hydrolysis of a novel glycolipid generates modulators of cAMP phosphodiesterase. (1986) (308)
- Interaction of insulin with the cell membrane: the primary action of insulin. (1969) (307)
- Insulin and epidermal growth factor. Human fibroblast receptors related to deoxyribonucleic acid synthesis and amino acid uptake. (1975) (306)
- Rapid formation of diacylglycerol from phosphatidylcholine: a pathway for generation of a second messenger. (1986) (304)
- Somatomedin-C stimulates the phosphorylation of the beta-subunit of its own receptor. (1983) (298)
- Morphiceptin (NH4-tyr-pro-phe-pro-COHN2): a potent and specific agonist for morphine (mu) receptors. (1981) (295)
- Phospholipase A2 activity specific for phosphatidic acid. A possible mechanism for the production of arachidonic acid in platelets. (1981) (290)
- Catalytic properties and specificity of the extracellular nuclease of Staphylococcus aureus. (1967) (287)
- Epidermal growth factor: receptors in human fibroblasts and modulation of action by cholera toxin. (1973) (282)
- Radioimmunoassay and characterization of enkephalins in rat tissues. (1978) (270)
- Isolation of the insulin receptor of liver and fat-cell membranes (detergent-solubilized-( 125 I)insulin-polyethylene glycol precipitation-sephadex). (1972) (263)
- Multiple opiate receptors (1980) (248)
- Insulin-like activity of concanavalin A and wheat germ agglutinin--direct interactions with insulin receptors. (1973) (242)
- Cellular receptor for 125I-labeled tumor necrosis factor: specific binding, affinity labeling, and relationship to sensitivity. (1985) (234)
- Local aggregation of hormone–receptor complexes is required for activation by epidermal growth factor (1979) (234)
- The purification of beta-galactosidase from Escherichia coli by affinity chromatography. (1971) (227)
- Stimulation of phosphatidic acid production in platelets precedes the formation of arachidonate and parallels the release of serotonin. (1979) (226)
- Resolution of high and low affinity epidermal growth factor receptors. Inhibition of high affinity component by low temperature, cycloheximide, and phorbol esters. (1982) (218)
- Phospholipase A2 and phospholipase C activities of platelets. Differential substrate specificity, Ca2+ requirement, pH dependence, and cellular localization. (1980) (218)
- Phorbol esters stimulate the phosphorylation of receptors for insulin and somatomedin C. (1983) (217)
- The mobile receptor hypothesis and "cooperativity" of hormone binding. Application to insulin. (1976) (216)
- Receptor-mediated uptake and degradation of 125I-chemotactic peptide by human neutrophils. (1979) (216)
- Properties of the insulin receptor isolated from liver and fat cell membranes. (1972) (214)
- Interaction of protein kinase C with membranes is regulated by Ca2+, phorbol esters, and ATP. (1985) (211)
- Epidermal growth factor. Characteristics of specific binding in membranes from liver, placenta, and other target tissues. (1974) (210)
- LACTASE DEFICIENCY IN THE ADULT. A COMMON OCCURRENCE. (1965) (205)
- Receptors and Recognition (1978) (204)
- Guanosine 3':5'-cyclic monophosphate and the action of insulin and acetylcholine. (1973) (203)
- Insulin stimulates the generation from hepatic plasma membranes of modulators derived from an inositol glycolipid. (1986) (202)
- Interaction of wheat germ agglutinin and concanavalin A with isolated fat cells. (1973) (200)
- The phosphatidylinositol cycle and the regulation of arachidonic acid production (1981) (199)
- Drug discovery in jeopardy. (2006) (198)
- Modulation of Adenylate Cyclase Activity in Liver and Fat Cell Membranes by Insulin (1972) (196)
- Peptide hormone-induced receptor mobility, aggregation, and internalization. (1981) (187)
- Binding of insulin and other hormones to non-receptor materials: saturability, specificity and apparent "negative cooperativity". (1975) (186)
- The initial action of thrombin on platelets. Conversion of phosphatidylinositol to phosphatidic acid preceding the production of arachidonic acid. (1981) (186)
- Regulation of arachidonate metabolism via lipoxygenase and cyclo-oxygenase by 12-HPETE, the product of human platelet lipoxygenase. (1979) (185)
- Protein kinase C phosphorylates topoisomerase II: topoisomerase activation and its possible role in phorbol ester-induced differentiation of HL-60 cells. (1986) (184)
- Aspirin-like drugs interfere with arachidonate metabolism by inhibition of the 12-hydroperoxy-5,8,10,14-eicosatetraenoic acid peroxidase activity of the lipoxygenase pathway. (1979) (183)
- Novel opiate binding sites selective for benzomorphan drugs (1981) (180)
- Properties of the insulin receptor of isolated fat cell membranes. (1971) (175)
- Amiloride inhibits phorbol ester-stimulated Na+/H+ exchange and protein kinase C. An amiloride analog selectively inhibits Na+/H+ exchange. (1985) (173)
- Affinity chromatography and purification of the insulin receptor of liver cell membranes. (1972) (173)
- Antibodies to purified insulin receptor have insulin-like activity. (1978) (170)
- Quantitative aspects of hormone-receptor interactions of high affinity. Effect of receptor concentration and measurement of dissociation constants of labeled and unlabeled hormones. (1975) (170)
- Receptor-mediated internalization of fluorescent chemotactic peptide by human neutrophils. (1979) (168)
- Insulin receptor: structure and function. (1981) (166)
- Association of phorbol ester-induced hyperphosphorylation and reversible regulation of transferrin membrane receptors in HL60 cells. (1984) (162)
- Receptor-mediated internalization of fluorescent gonadotropin-releasing hormone by pituitary gonadotropes. (1980) (161)
- Insulin receptor: covalent labeling and identification of subunits. (1979) (161)
- Membrane receptors. (1974) (154)
- Emergence of insulin receptors on human lymphocytes during in vitro transformation. (1972) (153)
- Possible requirement of internalization in the mechanism of in vitro cytotoxicity in tumor necrosis serum. (1981) (152)
- Role of intracellular calcium mobilization in the regulation of protein kinase C-mediated membrane processes (1985) (150)
- Estimation of hormone receptor affinity by competitive displacement of labeled ligand: effect of concentration of receptor and of labeled ligand. (1975) (143)
- Purification and properties of insulin receptors from rat liver membranes. (1977) (141)
- Binding of nerve growth factor receptor in sympathetic ganglia. (1973) (133)
- Unmasking of insulin receptors in fat cells and fat cell membranes. Perturbation of membrane lipids. (1971) (132)
- Noradrenaline binding and the search for catecholamine receptors (1974) (129)
- Osteoporosis, intestinal lactase deficiency and low dietary calcium intake. (1967) (129)
- Phosphatidylinositol-specific phospholipase-C of platelets: association with 1,2-diacyglycerol-kinase and inhibition by cyclic-AMP. (1979) (129)
- Perturbation of the Insulin Receptor of Isolated Fat Cells with Proteolytic Enzymes DIRECT MEASUREMENT OF INSULIN-RECEPTOR INTERACTIONS (1971) (128)
- Affinity chromatography and the purification of estrogen receptors. (1973) (126)
- Epidermal growth factor: biological activity requires persistent occupation of high-affinity cell surface receptors. (1978) (121)
- Single-step purification of avidine from egg white by affinity chromatography on biocytin-Sepharose columns. (1968) (120)
- Quantitative determination of the lateral diffusion coefficients of the hormone-receptor complexes of insulin and epidermal growth factor on the plasma membrane of cultured fibroblasts. (1978) (119)
- Membrane sialic acid and the mechanism of insulin action in adipose tissue cells. Effects of digestion with neuraminidase. (1971) (118)
- An immunohistochemical and radioimmunological study of the distribution of [Met5]- and [Leu5]-enkephalin in the gastrointestinal tract (1978) (118)
- Characterization of a neuronal subtype of insulin-like growth factor I receptor. (1987) (118)
- A role for cyclooxygenase products in the formation of phosphatidic acid in stimulated human platelets. Differential mechanisms of action of thrombin and collagen. (1983) (117)
- Interaction of concanavalin A and wheat germ agglutinin with the insulin receptor of fat cells and liver. (1973) (116)
- MAMMALIAN GALACTOKINASE. DEVELOPMENTAL AND ADAPTIVE CHARACTERISTICS IN THE RAT LIVER. (1965) (116)
- Cyclic adenosine monophosphate-dependent phosphorylation of specific fat cell membrane proteins by an endogenous membrane-bound protein kinase. Possible involvement in the regulation of insulin-stimulated glucose transport. (1974) (115)
- Insulin-receptor interactions in liver cell membranes. (1971) (115)
- Monensin blocks the maturation of receptors for insulin and somatomedin C: identification of receptor precursors. (1983) (115)
- Lack of association of epidermal growth factor-, insulin-, and serum-induced mitogenesis with stimulation of phosphoinositide degradation in BALB/c 3T3 fibroblasts. (1986) (114)
- Agarose Derivatives for Purification of Protein by Affinity Chromatography (1970) (114)
- An amyloid protein: the amino-terminal variable fragment of an immunoglobulin light chain. (1970) (113)
- The Specificity and Action of Animal, Bacterial and Plant Toxins (1977) (112)
- Mechanism of action of cholera toxin and the mobile receptor theory of hormone receptor-adenylate cyclase interactions. (1975) (112)
- Heterogeneity and properties of opiate receptors. (1981) (111)
- In search of a second messenger for insulin. (1988) (109)
- Arachidonate metabolism via lipoxygenase and 12L-hydroperoxy-5,8,10,14-icosatetraenoic acid peroxidase sensitive to anti-inflammatory drugs. (1980) (108)
- Mobility of cholera toxin receptors on rat lymphocyte membranes. (1975) (101)
- Adenosine triphosphate-dependent inhibition of insulin-stimulated glucose transport in fat cells. Possible role of membrane phosphorylation. (1974) (100)
- Phorbol esters rapidly stimulate amiloride-sensitive Na+/H+ exchange in a human leukemic cell line (1984) (100)
- Membrane receptors as general markers for plasma membrane isolation procedures. The use of 125-I-labeled wheat germ agglutinin, insulin, and cholera toxin. (1975) (100)
- The tyrosyl residues at the active site of staphylococcal nuclease. Modifications by tetranitromethane. (1968) (100)
- Fluorescent labeling of hormone receptors in viable cells: preparation and properties of highly fluorescent derivatives of epidermal growth factor and insulin. (1978) (98)
- Lysomotropic amines cause intracellular accumulation of receptors for epidermal growth factor. (1980) (95)
- Structural requirements for opioid activity of analogues of the enkephalins (1977) (95)
- Inhibitors of glucagon inactivation. Effect on glucagon--receptor interactions and glucagon-stimulated adenylate cyclase activity in liver cell membranes. (1974) (94)
- Aspirin-like drugs inhibit arachidonic acid metabolism via lipoxygenase and cyclo-oxygenase in rat neutrophils from carrageenan pleural exudates. (1980) (94)
- Insulin Insensitivity of Large Fat Cells (1972) (93)
- Purification of neuraminidases from Vibrio Cholerae, Clostridium Perfringens and influenza virus by affinity chromatography. (1971) (93)
- Cholera toxin mimics melanocyte stimulating hormone in inducing differentiation in melanoma cells. (1974) (92)
- Studies of glucagon resistance in large rat adipocytes: 125I-labeled glucagon binding and lipolytic capacity. (1974) (92)
- Analgesic activity of intracerebroventricular administration of morphiceptin and β-casomorphins: Correlation with the morphine (μ) receptor binding affinity (1982) (91)
- The subunit structure of rat liver insulin receptor. Antibodies directed against the insulin-binding subunit. (1980) (90)
- Cholera toxin and cell growth: role of membrane gangliosides. (1974) (89)
- Cholera toxin-fat cell interaction and the mechanism of activation of the lipolytic response. (1973) (89)
- Hormone receptor complexes and their modulation of membrane function. (1975) (89)
- Vibrio cholerae choleragenoid. Mechanism of inhibition of cholera toxin action. (1973) (86)
- Opiate (Enkephalin) receptors of neuroblastoma cells: occurrence in clusters on the cell surface. (1979) (86)
- The metabolic stability of the enkephalins. (1977) (85)
- Mechanism of phorbol diester-induced regulation of surface transferrin receptor involves the action of activated protein kinase C and an intact cytoskeleton. (1985) (83)
- Preliminary characterization of the tumor cell cytotoxin in tumor necrosis serum. (1981) (83)
- 8 Staphylococcal Nuclease, Chemical Properties and Catalysis (1971) (82)
- Modulation of binding and bioactivity of insulin by anti-insulin antibody: relation to possible role of receptor self-aggregation in hormone action. (1979) (82)
- Interaction of enkephalin with opiate receptors in intact cultured cells. (1978) (81)
- Phosphorylation of receptors for insulin and insulin-like growth factor I. Effects of hormones and phorbol esters. (1986) (81)
- Affinity chromatography and structural analysis of Vibrio cholerae [Vibrio Comma] enterotoxin-ganglioside agarose and the biological effects of ganglioside-containing soluble polymers (1973) (81)
- Covalent affinity labeling of the formyl peptide chemotactic receptor. (1980) (81)
- Esterification of an endogenously synthesized lipoxygenase product into granulocyte cellular lipids. (1981) (79)
- Interactions of ligands with morphine and enkephalin receptors are differentially affected by guanine nucleotide. (1981) (76)
- Brain enkephalin distribution is unaltered by hypophysectomy. (1978) (74)
- Establishment of the interferon-mediated antiviral state: role of fatty acid cyclooxygenase. (1980) (74)
- Insulin-sepharose: immunoreactivity and use in the purification of antibody. (1969) (74)
- HUMAN AMYLOID PROTEIN: CHEMICAL VARIABILITY AND HOMOGENEITY (1971) (74)
- Endogenous prostaglandins modulate lipolytic processes in adipose tissue. (1971) (73)
- A subpopulation of cultured human promyelocytic leukemia cells (HL-60) displays the formyl peptide chemotactic receptor. (1980) (73)
- Phorbol ester receptors and protein kinase C in primary neuronal cultures: development and stimulation of endogenous phosphorylation (1986) (72)
- Interaction of iodinated enkephalin analogues with opiate receptors. (1978) (72)
- LACTASE DEFICIENCY IN THE ADULT (1965) (72)
- Cytoskeletal calmodulin-dependent protein kinase. Characterization, solubilization, and purification from rat brain. (1985) (71)
- Morphine in cow and human milk: could dietary morphine constitute a ligand for specific morphine (mu) receptors? (1981) (70)
- The production of 5-HETE and leukotriene B in rat neutrophils from carrageenan pleural exudates. (1981) (67)
- AMYLOID. VI. A COMPARISON OF TWO MORPHOLOGIC COMPONENTS OF HUMAN AMYLOID DEPOSITS (1968) (66)
- Changes in fatty acyl chains of phospholipids induced by interferon in mouse sarcoma S-180 cells. (1981) (65)
- Putative mediators of insulin action: regulation of pyruvate dehydrogenase and adenylate cyclase activities. (1982) (65)
- Receptors and Recognition: Series A (1978) (65)
- Acromegaly and other disorders of growth hormone secretion. Combined clinical staff conference at the National Institutes of Health. (1967) (65)
- The appearance of phospholipase and cyclo-oxygenase activities in the human promyelocytic leukemia cell line HL60 during dimethyl sulfoxide-induced differentiation. (1981) (65)
- Insulin stimulates the release from liver plasma membranes of a chemical modulator of pyruvate dehydrogenase. (1981) (63)
- Lysosomotropic amines inhibit mitogenesis induced by growth factors. (1981) (63)
- The defect in insulin receptors in obese-hyperglycemic mice: a probable accompaniment of more generalized alterations in membrane glycoproteins. (1975) (63)
- Rapid inactivation of cyclooxygenase activity after stimulation of intact platelets. (1979) (61)
- Chemical identification of a tumor-derived angiogenic factor. (1987) (60)
- Insulin Receptor of Fat Cells in Insulin-Resistant Metabolic States (1972) (60)
- Mechanism of activation of adenylate cyclase by cholera toxin. (1975) (59)
- Protein kinase C: rapid enzyme purification and substrate-dependence of the diacylglycerol effect. (1984) (58)
- Formyl peptide chemotactic receptors of leukocytes and macrophages. (1980) (57)
- Transferrin receptor: Its biological significance (2005) (57)
- Ca2+-calmodulin-dependent protein kinase in neuronal nuclei. (1984) (57)
- Action of corticosteroids in regulation of prostaglandin biosynthesis in cultured fibroblasts. (1978) (57)
- MURINE AMYLOID FIBRIL PROTEIN: ISOLATION, PURIFICATION AND CHARACTERIZATION (1971) (56)
- The oxidation of C14galactose by patients with congenital galactosemia: Evidence for a direct oxidative pathway (1968) (56)
- The action of staphylococcal nuclease on synthetic substrates. (1969) (56)
- Ionophore A-23187- and thrombin-induced platelet aggregation: independence from cycloxygenase products. (1978) (56)
- Role of disulphide and sulphydryl groups in clustering of enkephalin receptors in neuroblastoma cells (1979) (55)
- Affinity chromatography of macromolecules. (1972) (55)
- Protein kinase associated with tubulin: affinity chromatography and properties. (1976) (54)
- Intracellular activation of protein kinase C and regulation of the surface transferrin receptor by diacylglycerol is a spontaneously reversible process that is associated with rapid formation of phosphatidic acid. (1986) (54)
- Modulation of cyclic AMP metabolism by S-adenosylhomocysteine and S-3-deazaadenosylhomocysteine in mouse lymphocytes. (1980) (53)
- Ca2+/calmodulin-dependent protein kinases from the neuronal nuclear matrix and post-synaptic density are structurally related. (1984) (52)
- An improved method for the purification of staphylococcal nuclease. (1967) (52)
- Possible role of distinct morphine and enkephalin receptors in mediating actins of benzomorphan drugs (putative kappa and sigma agonists). (1980) (52)
- Affinity labeling of the active site of staphylococcal nuclease. Reactions with bromoacetylated substrate analogues. (1969) (52)
- Glucose transport in fat cell membranes. (1971) (52)
- Insulin receptor of liver and fat cell membranes. (1973) (51)
- Insulin receptors, cell membranes and hormone action (1974) (51)
- Putative mediators of insulin action regulate hepatic acetyl CoA carboxylase activity. (1983) (50)
- Stimulation of glycogen synthesis by insulin in human erythroleukemia cells requires the synthesis of glycosyl-phosphatidylinositol. (1994) (50)
- Characterization of the association of tritiated enkephalin with neuroblastoma cells under conditions optimal for receptor down regulation. (1983) (50)
- Inhibition of epidermal growth factor-induced mitogenesis by amiloride and an analog: evidence against a requirement for Na+/H+ exchange. (1984) (50)
- Cluster formation of opiate (enkephalin) receptors in neuroblastoma cells: differences between agonists and antagonists and possible relationships to biological functions. (1980) (49)
- Increased biological activity of dimers of oxymorphone and enkephalin: possible role of receptor crosslinking. (1982) (49)
- Diacylglycerol-induced translocation of diacylglycerol kinase: use of affinity-purified enzyme in a reconstitution system. (1986) (49)
- Purification of phosphatidylinositol kinase from bovine brain myelin. (1987) (48)
- Mechanism of action of Vibrio cholerae enterotoxin. Effects on adenylate cyclase of toad and rat erythrocyte plasma membranes. (1975) (48)
- Insulin receptors in murine mammary cells: comparison in pregnant and nonpregnant animals. (1974) (48)
- The binding of nucleotides and calcium to the extracellular nuclease of Staphylococcus aureus. Studies by gel filtration. (1967) (47)
- Fluorescent and photo-affinity enkephalin derivatives: preparation and interaction with opiate receptors. (1979) (45)
- Enkephalins and endorphins. (1978) (45)
- Purification of oestradiol receptors by affinity chromatography. (1973) (45)
- Interferon-resistant cell line lacks fatty acid cyclooxygenase activity. (1981) (45)
- Naloxazone irreversibly inhibits the high affinity binding of [125I]D-ala2-D-leu5-enkephalin. (1981) (44)
- Purification of insulin-like growth factor I receptor from human placental membranes. (1986) (44)
- Insulin-induced reduction of membrane receptor concentrations in isolated fat cells and lymphocytes. Independence from receptor occupation and possible relation to proteolytic activity of insulin. (1975) (43)
- "Galactose Dehydrogenase," "Nothing Dehydrogenase," and Alcohol Dehydrogenase: Interrelation (1967) (42)
- Digestion of insulin receptors with proteolytic and glycosidic enzymes-effects on purified and membrane-associated receptor subunits. (1980) (42)
- Rapid acylation and deacylation of arachidonic acid into phosphatidic acid of horse neutrophils. (1980) (41)
- Brain and caudate nucleus adenylate cyclase: Effects of dopamine, GTP, E prostaglandins and morphine (1975) (41)
- Specific phospholipids are required to reconstitute adenylate cyclase solubilized from rat brain. (1981) (41)
- Calmodulin binding to the cytoskeletal neuronal calmodulin-dependent protein kinase is regulated by autophosphorylation. (1985) (41)
- Activation of adenylate cyclase by phosphoramidate and phosphonate analogs of GTP: possible role of covalent enzyme-substrate intermediates in the mechanism of hormonal activation. (1975) (41)
- Cross-linking of aminotyrosyl residues in the active site of staphylococcal nuclease. (1969) (40)
- PHYSICAL AND CHEMICAL PROPERTIES OF AMYLOID FIBERS II. ISOLATION OF A UNIQUE PROTEIN CONSTITUTING THE MAJOR COMPONENT FROM HUMAN SPLENIC AMYLOID FIBRIL CONCENTRATES (1969) (40)
- Mammalian galactose dehydrogenase. I. Identification and purification in rat liver. (1966) (39)
- Structure and function of cholera toxin and hormone receptors. (1976) (39)
- Benzomorphan sites are ligand recognition sites of putative epsilon-receptors. (1984) (39)
- Disulfide reduction converts the insulin receptor of human placenta to a low affinity form. (1980) (39)
- Interaction of iodinated human [D-Ala2]beta-endorphin with opitate receptors. (1979) (39)
- A monoclonal antibody to human insulin receptor. (1982) (39)
- Complete glycosylation of the insulin and insulin-like growth factor I receptors is not necessary for their biosynthesis and function. Use of swainsonine as an inhibitor in IM-9 cells. (1986) (38)
- Independence of glucagon receptors and glucagon inactivation in liver cell membranes. (1972) (38)
- Mammalian galactose dehydrogenase. II. Properties, substrate specificity, and developmental changes. (1966) (38)
- Distinction of Receptor from Nonreceptor Interactions in Binding Studies (1979) (38)
- Opposing effects of cyclic AMP and cyclic GMP on protein phosphorylation in tubulin preparations (1976) (38)
- Novel opiate binding sites selective for benzomorphan drugs. (1981) (38)
- Topography of the active site of staphylococcal nuclease. Affinity labeling with diazonium substrate analogues. (1970) (38)
- Effects of insulin, epinephrine, and cyclic adenosine monophosphate on pyruvate dehydrogenase of adipose tissue. (1973) (37)
- Necrosin: purification and properties of a cytotoxin derived from a murine macrophage-like cell line. (1984) (37)
- Hormone receptors - their function in cell membranes and some problems related to methodology. (1975) (37)
- Murine amyloidosis: immunologic characterization of amyloid fibril protein. (1971) (36)
- The Insulin Receptor (1972) (36)
- A CONFORMATIONAL ANALYSIS FOR LEUCINE‐ENKEPHALIN USING ACTIVITY AND BINDING DATA OF SYNTHETIC ANALOGUES (1977) (36)
- Establishment of the interferon-mediated antiviral state: possible role of superoxide dismutase. (1981) (36)
- Preparation of inverted plasma membrane vesicles from isolated adipocytes. (1973) (36)
- myo-Inositol 1,4,5-trisphosphate stimulates protein phosphorylation in saponin-permeabilized human platelets. (1984) (35)
- Changes in the binding of concanavalin A and wheat germ agglutinin to human lymphocytes during in vitro transformation. (1973) (34)
- Early postnatal development of calmodulin-dependent protein kinase II in rat brain. (1985) (34)
- Role of nucleotides in tubulin polymerization: effect of guanylyl 5'-methylenediphosphonate. (1977) (33)
- Molecular complexes involved in the regulation of adenylate cyclase. (1981) (33)
- Persistence of exogenous, inserted ganglioside GM1 on the cell surface of cultured cells. (1977) (33)
- Staphylococcal Nuclease: Size and Specificity of the Active Site (1968) (33)
- Lysophosphatidic acid potentiates the thrombin-induced production of arachidonate metabolites in platelets. (1981) (33)
- [34] β-Galactosidase (1974) (32)
- Affinity chromatography and structural analysis of Vibrio cholerae enterotoxin-ganglioside agarose and the biological effects of ganglioside-containing soluble polymers. (1973) (32)
- Nerve growth factor receptor binding. Influence of enzymes, ions, and protein reagents. (1975) (31)
- Proteins associated with tubulin. (1976) (29)
- Prolactin stimulation by thyrotropin-releasing hormone in a patient with isolated thyrotropin deficiency. (1972) (29)
- Glucagon affinity absorbents: selective binding of receptors of liver cell membranes. (1971) (29)
- Fluorescence studies of the interaction of nucleotides with the active site of the nuclease of Staphylococcus aureus. (1967) (29)
- The interaction of nucleotides with the active site of staphylococcal nuclease. Spectrophotometric studies. (1967) (29)
- Genetic engineering and pharmaceuticals (1984) (28)
- Beta-adrenergic receptors: stereospecificity and lack of affinity for catechols. (1974) (28)
- Epinephrine stimulation of fat cell adenylate cyclase: regulation by guanosine-5'-triphosphate and magnesium ion. (1974) (27)
- AFFINITY CHROMATOGRAPHY: A valuable technique for purifying enzymes, studying cell interactions, and exploring hormone receptors may also have potential in treating disease (1985) (27)
- Purification of tyrosine aminotransferase by affinity chromatography. (1972) (27)
- Accumulation of epidermal growth factor within cells does not depend on receptor recycling. (1980) (26)
- Partial purification by affinity chromatography of tyrosine aminotransferase-synthesizing ribosomes from hepatoma tissue culture cells. (1971) (26)
- Topographic separation of adenylate cyclase and hormone receptors in the plasma membrane of toad erythrocyte ghosts. (1977) (25)
- Exposure of cells to an acidic environment reverses the inhibition by methylamine of the mitogenic response to epidermal growth factor. (1982) (25)
- A specific phosphoprotein phosphatase acts on histone H1 phosphorylated by protein kinase C. (1983) (24)
- Distribution and pharmacology of the enkephalins and related opiate peptides (1978) (24)
- Mechanism of activation of adenylate cyclase by Vibrio cholerae enterotoxin. Relations to the mode of activation by hormones. (1975) (24)
- The mobile receptor hypothesis for cell membrane receptor action (1977) (24)
- Solubilization of nerve growth factor receptors of rabbit superior cervical ganglia. (1976) (23)
- Chemotactic peptide stimulated endogenous arachidonic acid metabolism in HL-60 granulocytes. (1981) (23)
- Cholera Toxin: Membrane Gangliosides and Activation of Adenylate Cyclase (1977) (23)
- Guanylate cyclase. Existence of different forms and their regulation by nucleotides in calf uterus. (1976) (23)
- Activation of pigeon erythrocyte adenylate cyclase by cholera toxin. Partial purification of an essential macromolecular factor from horse erythrocyte cytosol. (1981) (23)
- Skeletal association of the cholera toxin receptor in rat erythrocytes. (1981) (22)
- Specific postsynaptic density proteins bind tubulin and calmodulin-dependent protein kinase type II. (1986) (22)
- Incorporation of rat brain adenylate cyclase into artificial phospholipid vesicles. (1979) (22)
- Unmasking of magnesium-dependent high-affinity binding sites for [dAla2, dLeu5]enkephalin after pretreatment of brain membranes with guanine nucleotides. (1983) (22)
- 2'-Deoxyadenosine-3'-monophosphate: a naturally occurring inhibitor of adenylate cyclase in amphibian and mammalian cells. (1976) (22)
- The lipoxygenase product, 5-hydroperoxy-arachidonic acid, augments chemotactic peptide-stimulated arachidonic acid release from HL60 granulocytes. (1982) (21)
- Cell receptors in disease. (1977) (21)
- Cytochalasins inhibit arachidonic acid metabolism in thrombin-stimulated platelets. (1982) (21)
- Binding of calmodulin to the neuronal cytoskeletal protein kinase type II cooperatively stimulates autophosphorylation. (1986) (21)
- Correlation between the antigenic and catalytic properties of staphylococcal nuclease. (1969) (21)
- Membrane receptors and hormone action: Recent developments (1978) (20)
- Receptor redistribution induced by hormones and neurotransmitters: Possible relationships to biological functions (1981) (20)
- Effect of sodium molybdate on cytosolic estrogen receptor. (1982) (20)
- Membrane receptors : methods for purification and characterization (1981) (20)
- CHAPTER 2 – Selective Adsorbents Based on Biochemical Specificity (1971) (19)
- Evidence for cytoskeletal associations of the adenylate cyclase system obtained by differential extraction of rat erythrocyte ghosts. (1981) (19)
- Rapid degradation of [3H]leucine-enkephalin by intact neuroblastoma cells. (1979) (18)
- , -methylene-adenosine 5'-triphosphate. A competitive inhibitor of adenylate cyclase in fat and liver cell membranes. (1973) (18)
- Hormone receptors, membrane phospholipids, and protein kinases. (1984) (18)
- Substrate analog competitive inhibitors of human renin. (1973) (17)
- Affinity chromatography of insulin receptors. (1974) (16)
- Demonstration of choleragen-dependent ADP-ribosylation in whole cells and correlation with the activation of adenylate cyclase. (1980) (15)
- An overview of toxin-receptor interactions. (1981) (15)
- The function of glycosyl phosphoinositides in hormone action. (1988) (15)
- Phorbol ester-induced lymphocyte adherence: selective action on NK cells. (1985) (15)
- [86] Estrogen receptors (1974) (14)
- Insulin: interaction with membrane receprots and relationship to cyclic purine nucleotides and cell growth. (1975) (14)
- Editorial: Problems in receptor identification: catecholamines. (1974) (14)
- Studies of the aromatic circular dichroism of Staphylococcal nuclease. (1969) (14)
- Cytosolic activator of adenylate cyclase: Reconstitution, characterization, and mechanism of action. (1983) (13)
- The structural basis of the catalytic function of staphylococcal nuclease. (1968) (13)
- Inhibition of 125I-chemotactic peptide uptake by protease inhibitors. (1980) (13)
- Molecular resolution and reconstitution of the GPP (NH) P and NAF sensitive adenylate cyclase system. (1977) (13)
- , -Methylene-adenosine-5'-triphosphate--effects of a competitive inhibitor of adenylate cyclase on cyclic AMP accumulation and lipolysis in isolated fat cells. (1973) (13)
- Long-term epidermal growth factor-receptor internalization and processing in quiescent human fibroblasts. (1981) (12)
- Affinity Chromatography (1971) (12)
- Properties of the interaction of fluoride- and guanylyl-5'-imidodiphosphate-regulatory proteins with adenylate cyclase. (1978) (12)
- Role of extracellular arachidonate in regulation of prostaglandin biosynthesis in cultured 3T3 fibroblasts. (1980) (11)
- Neurobiology and neuropharmacology of the enkephalins. (1979) (11)
- Studies on the mechanism of enkephalin receptor down regulation. (1982) (11)
- Metabolism of lactose by intestinal mucosa from normal and lactase-deficient subjects. (1967) (11)
- Special Report: Affinity Chromatography. (1985) (11)
- Role of specific membrane lipids in modulating the activity of adenylate cyclase. (1982) (11)
- Specific binding of solubilized adenylate cyclase to the erythrocyte cytoskeleton. (1981) (11)
- Mechanism of activation of adenylate cyclase byVibrio cholerae enterotoxin (1975) (10)
- Insulin receptor antibodies. (1981) (10)
- Quantification and properties of tubulin polymerization in crude brain extracts and preparations of microtubular and purified tubulin. (1978) (10)
- Formation and identification of cytoskeletal components from liver cytosolic precursors. (1982) (10)
- Thrombin and bradykinin modulate prostaglandin synthetase independently of phospholipase. (1980) (9)
- Possible role of distinct morphine and enkephalin receptors in mediating actions of benzomorphan drugs ( putative K and o ' agonists ) (9)
- CHAPTER 3 – Studies on the Interaction of Hormones with Plasma Membrane Receptors (1975) (9)
- Inhibition of fat cell membrane adenylate cyclase by 2'-deoxyadenosine-3'-monophosphate,. (1976) (9)
- CHOLERA TOXIN, MEMBRANE GLYCOLIPIDS AND THE MECHANISM OF ACTION OF PEPTIDE HORMONES (1976) (9)
- Specificity of a phosphatase for phospholipid, Ca2+-dependent protein kinase-phosphorylated histone H1 resides in the catalytic subunit. (1984) (9)
- Production of anti-glucagon antibodies in poly-L-lysine "responder" guinea-pigs. (1971) (9)
- Drug safety: phenacetin. (1979) (8)
- Binding of (3H)guanylylimidodiphosphate to membranes: lack of correlation with adenylate cyclase activation. (1976) (8)
- Determination of calmodulin by competitive binding assay. (1986) (8)
- Hormone-Receptor Interactions and the Plasma Membrane (1974) (8)
- The effect of a competitive inhibitor on the acetylation of tyrosyl and lysyl residues of staphylococcal nuclease. (1968) (8)
- Epidermal growth factor: uptake and fate. (1982) (8)
- Visualization of enkephalin receptors by image-intensified fluorescence microscopy. (1983) (8)
- Analgesic activity of intracerebroventricular administration of morphiceptin and beta-casomorphins: correlation with the morphine (micro) receptor binding affinity. (1982) (8)
- Affinity Chromatography in Immunology (1977) (7)
- Kinetics of irreversible activation of adenylate cyclase of fat cell membranes by phosphonium and phosphoramidate analogs of gtp1. (1976) (7)
- Macromolecular naloxone: a novel long-acting polymer-bound drug. (1976) (7)
- Affinity chromatography--old problems and new approaches. (1974) (7)
- Developing Concepts in Receptor Research (1983) (7)
- Regulation of phospholipase activity in platelets. (1978) (7)
- [122] Purification of neuraminidases (sialidases) by affinity chromatography (1972) (7)
- The Distributed Partnering Model for Drug Discovery and Development (2010) (7)
- Insulin receptors. (1983) (7)
- Functional purification of proteins and peptides by affinity chromatography. (1971) (7)
- Role of nucleotides in tubulin polymerization: effect of guanosine 5'-methylene diphosphonate. (1978) (7)
- Endogenous dephosphorylation of synaptosomal calmodulin-dependent protein kinase type II. (1985) (7)
- [35] Purification of insulin receptor from human placenta (1985) (6)
- Cholera toxin and membrane gangliosides: Binding and adenylate cyclase activation in normal and transformed cells (1978) (6)
- Immunological probes into the mechanism of cholera toxin action. (1976) (6)
- Mechanism of action ofVibrio cholerae enterotoxin (1975) (6)
- Staphylococcal nuclease. (1977) (6)
- Biochemical Identification of Membrane Receptors: Principles and Techniques (1975) (6)
- [79] Ganglioside-agarose and cholera toxin (1974) (6)
- Receptor-Mediated Endocytosis (1983) (6)
- Corporate America: Creativity Held Hostage (1995) (5)
- Interferon-mediated changes in lipid metabolism. (1981) (5)
- Histones H3 and H4 inhibit protein kinase C specifically. (1983) (5)
- Mechanism of activation of adenylate cyclase byVibrio cholerae enterotoxin (2005) (5)
- Arachidonate metabolism via lipoxygenase and 12 L-hydroperoxy-5 , 8 , 10 , 14-icosatetraenoic acid peroxidase sensitive to anti-inflammatory drugs ( aspirin / salicylate / indomethacin / acetaminophen / human platelets ) (5)
- Phospholipase Az Activity Specific for Phosphatidic Acid (2001) (5)
- Purification of insulin receptor from human placenta. (1985) (4)
- Affinity Chromatography for Membrane Receptor Purification (1981) (4)
- Effects of insulin on the adenylyl cyclase activity of isolated fat cell membranes (1978) (3)
- Stimulation and modulation of adenylate cyclase by Sendai virus. (1976) (3)
- Affinity Chromatography, Principles and Applications (1975) (3)
- Problems in Studying Hormone Receptor Binding (1979) (3)
- Kinetic studies of adenylyl cyclase of fat cell membranes (1978) (3)
- Properties of rat erythrocyte membrane cytoskeletal structures produced by digitonin extraction: Digitonin-insoluble β-adrenergic receptor, adenylate cyclase, and cholera toxin substrate (2005) (3)
- Insulin receptors and insulin receptor antibodies: structure-function relationships. (1982) (3)
- HORMONE RECEPTORS AND THEIR FUNCTION IN CELL MEMBRANES (1974) (3)
- The enkephalins (1978) (3)
- Phenacetin studies. (1979) (3)
- Criteria for and pitfalls in the identification of receptors. (1975) (3)
- Immobilized Enzymes. Oskar Zaborsky. CRC Press (Chemical Rubber Co.), Cleveland, Ohio, 1973. xiv, 176 pp., illus. $26.50 (1974) (3)
- Activation of adenylate cyclase by Guanosine 5′ α, β methylene triphosphate (1977) (2)
- Adsorptive Pinocytosis of Epidermal Growth Factor: Studies of its Relevance to Mitogenesis (1983) (2)
- [38] Staphylococcal nuclease (1977) (2)
- Contemporary drug development--dilemmas. (1984) (2)
- Rapid purification of chicken gizzard α-actinin (1979) (2)
- Internalization and Processing of Peptide Hormone Receptors (1985) (2)
- Competitive binding assay for drugs that interfere with calmodulin function. (1985) (2)
- Insulin receptors. (1973) (2)
- Insulin Receptor Interactions and the Action of Insulin (1975) (2)
- Difference between the calcium- and the phorbol ester-induced association of protein kinase C with phospholipid membrane. (1990) (2)
- Affinity Chromatography An Overview (1993) (2)
- THE NERVE GROWTH FACTOR RECEPTOR: DEMONSTRATION OF SPECIFIC BINDING IN SYMPATHETIC GANGLIA (1974) (2)
- Substitution by fatty acids for phosphatidylserine in a reconstitution of phorbol ester binding to protein kinase C. (1991) (1)
- Isolation and characterization of hormone receptors. (1973) (1)
- Introduction: A perspective in drug discovery and development (1982) (1)
- EMERGING CONCEPTS IN THE MECHANISM OF ACTION OF MEMBRANE RECEPTORS (1983) (1)
- Irreversible stimulation of adenylate cyclase activity of fat cell membranes by phosphoramidate and phosphonate analogs of GTP (2005) (1)
- Unmasking of magnesium-dependent high affinity binding sites for [ DAa 2 , DLeu 5 ] enkephalin after pretreatment of brain membranes with guanine nucleotides ( opiate receptors / morphiceptin / GDP / GTP / receptor regulation ) (1)
- Isolation of beta-galactosidase by chromatography. (1974) (1)
- Rapid purification of chicken gizzard alpha-actinin. (1979) (1)
- Ganglioside-agarose and cholera toxin. (1974) (1)
- Some Perspectives on the Hormone-stimulated Adenylate Cyclase System (1981) (1)
- Commentary. Insulin receptors, cell membranes and hormone action. (1974) (1)
- Response : Biological Activity of Insulin-Sepharose? (1973) (1)
- Rapidinactivation ofcyclooxygenase activity after stimulation ofintact platelets (lipoxygenase/arachidonate/phospholipases/aggregation/self-regulation) (1979) (0)
- Enzyme immobilization and adsorbents with biologic specificity. (1973) (0)
- Biochemical problems in the study of the insulin receptor. (1977) (0)
- Biochemical Tools: Immobilized Enzymes . Oskar Zaborsky. CRC Press (Chemical Rubber Co.), Cleveland, Ohio, 1973. xiv, 176 pp., illus. $26.50 (1974) (0)
- Architecture of Plasma Membrane Hormone Receptor-Effector Systems (1984) (0)
- Binding of exogenous brain protein kinase C to liver nuclei (1986) (0)
- "Galactose dehydrogenase", "nothing dehydrogenase", and alcohol dehydrogenase: interrelation. (1967) (0)
- Monoclonal Antibodies as Probes for Insulin and Insulin-like Growth Factor-I Receptors (1984) (0)
- drug combinations comprising prostacyclin or dihydroprostacycline (1978) (0)
- Effects of ATP concentration on the activation of rat brain protein kinase (1990) (0)
- Pharmacodynamics of a long acting opiate antagonist in mice: macro naloxone (1975) (0)
- 48 – Visualization of Enkephalin Receptors by Image-Intensified Fluorescence Microscopy (1989) (0)
- Macrophage cytotoxin: Sources and mechanism☆☆☆ (1982) (0)
- Combined effects of insulin , wheat germ agglutinin , and concanavalin A on glucose oxidation by isolated fat cells (0)
- Procedure kits and biotin-labeled antibody for the qualitative and / or quantitative determination of a biological substance in a sample. (1979) (0)
- Mechanism ofActionofCholera ToxinandtheMobileReceptor Theoryof (1975) (0)
- Response : Insulin Activity: The Solid Matrix (1973) (0)
- Method, equipment and composition for qualitative analysis and enzyme immunoassay of biological substances (1980) (0)
- Fluorescent chemo tactic peptide visualization of binding and internalization by human neutrophils (1979) (0)
- Kinetic studies of adenylyl cyclase of fat cell membranes (1978) (0)
- Identification of specific nerve growth factor (NGF) binding in superior cervical ganglia (1973) (0)
- Isolation oftheInsulin Receptor ofLiver andFat-Cell Membranes (1972) (0)
- Affinity chromatography. (1972) (0)
- I to reconstitute adenylate (2016) (0)
- Possible Requirement of Internalizaron in the Mechanism of in Vitro Cytotoxicity in Tumor Necrosis Serum1 (2006) (0)
- 1340 – PROBLEMS IN STUDYING HORMONE RECEPTOR BINDING (1978) (0)
- Kinetic studies on insulin inhibition of fat cell adenylyl cyclase. (1979) (0)
- Mass Spectrometry Applications in a Pharmaceutical Laboratory (1978) (0)
- Insulin Receptor Structure and Antibodies (1982) (0)
- The enkephalins. Peptides with morphine-like activity. (1978) (0)
- A pharmaceutical preparation for prevention of platelet aggregation (1978) (0)
- (epidermal growth factor/insulin/receptor-mediated degradation/internalization) (2016) (0)
- 1136 – METHODS AND PROBLEMS IN THE STUDY OF MEMBRANE RECEPTORS (1977) (0)
- Protein kinase C and simulated ischemia possible aberrations of signal transduction during ischemia (1989) (0)
- Recipient of the 1999 SBS Achievement Award (1999) (0)
- Regulation of cellular lipid metabolism by interferon and its relationship to interferon-mediated antiviral state ☆ ☆☆ (1982) (0)
- The Phosphatidylinositol Response and the Activation of Platelets (1983) (0)
- CHAPTER 23 – Excursions of a Protein Vagabond: From Nuclease to Affinity Chromatography to Hormone Receptors and Membranes (1984) (0)
- Practice and kits for the qualitative and or quantitative determination of a biological substance in a sample (1979) (0)
- Drug Discovery and Development (2010) (0)
- Phorbol EstersRapidly StimulateAmiloride-sensitive Na'/H' Exchange ina Human Leukemic Cell Line (2013) (0)
- Irreversible activation of adenylate cyclase of toad erythrocyte plasma membrane by 5′-guanylylimidodiphosphate (2005) (0)
- New insights in receptor signal transduction (1995) (0)
- Formation andidentification ofcytoskeletal components fromliver cytosolic precursors (1982) (0)
- Activation of adenylate cyclase by guanosine 5' alpha, beta methylene triphosphate. (1977) (0)
- Affinity chromatography of estrogen receptors. (1974) (0)
- Some Novel Phospholipase C Activities (1988) (0)
- MEMBRANE RECEPTORS 1 (1974) (0)
- Procedure, kits and biotin-labeled antibody for detection and / or quantitative determination of a biological substance in a praeve. (1979) (0)
- Drug Safety: Phenacetin (1979) (0)
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