Pere B. Puigserver
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Pere B. Puigserverbiology Degrees
Biology
#10700
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#14052
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Molecular Biology
#1581
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#1609
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Biochemistry
#1718
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#1853
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Biology
Pere B. Puigserver's Degrees
- PhD Biochemistry University of Barcelona
Why Is Pere B. Puigserver Influential?
(Suggest an Edit or Addition)Pere B. Puigserver's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes (2003) (6859)
- Resveratrol improves health and survival of mice on a high-calorie diet (2006) (4154)
- Mechanisms Controlling Mitochondrial Biogenesis and Respiration through the Thermogenic Coactivator PGC-1 (1999) (3848)
- Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α (2006) (3817)
- A Cold-Inducible Coactivator of Nuclear Receptors Linked to Adaptive Thermogenesis (1998) (3709)
- AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity (2009) (2302)
- Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres (2002) (2201)
- Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator. (2003) (2005)
- Transcriptional regulation of adipogenesis. (2000) (1987)
- Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1 (2005) (1937)
- Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1 (2001) (1845)
- Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. (2005) (1420)
- CREB regulates hepatic gluconeogenesis through the coactivator PGC-1 (2001) (1376)
- Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres. (2002) (1310)
- Insulin-regulated hepatic gluconeogenesis through FOXO1–PGC-1α interaction (2003) (1277)
- mTOR controls mitochondrial oxidative function through a YY1–PGC-1α transcriptional complex (2007) (1268)
- Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC‐1α (2007) (1199)
- SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis (2007) (1001)
- Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment (2009) (896)
- Cytokine stimulation of energy expenditure through p38 MAP kinase activation of PPARgamma coactivator-1. (2001) (744)
- Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction. (2003) (715)
- Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1 (2001) (670)
- Errα and Gabpa/b specify PGC-1α-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle (2004) (614)
- Neuronal SIRT1 Activation as a Novel Mechanism Underlying the Prevention of Alzheimer Disease Amyloid Neuropathology by Calorie Restriction* (2006) (591)
- Fasting-dependent glucose and lipid metabolic response through hepatic sirtuin 1 (2007) (551)
- Activation of PPARγ coactivator-1 through transcription factor docking (1999) (545)
- PGC1α expression defines a subset of human melanoma tumors with increased mitochondrial capacity and resistance to oxidative stress. (2013) (541)
- Regulation of hepatic fasting response by PPARγ coactivator-1α (PGC-1): Requirement for hepatocyte nuclear factor 4α in gluconeogenesis (2003) (535)
- Metabolic adaptations through the PGC‐1α and SIRT1 pathways (2008) (521)
- p38 Mitogen-Activated Protein Kinase Is the Central Regulator of Cyclic AMP-Dependent Transcription of the Brown Fat Uncoupling Protein 1 Gene (2004) (512)
- Peroxisome Proliferator-activated Receptor γ Coactivator 1β (PGC-1β), A Novel PGC-1-related Transcription Coactivator Associated with Host Cell Factor* (2002) (489)
- Survival of tissue-resident memory T cells requires exogenous lipid uptake and metabolism (2017) (454)
- GCN5 acetyltransferase complex controls glucose metabolism through transcriptional repression of PGC-1alpha. (2006) (426)
- Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1. (2000) (408)
- Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle. (2004) (368)
- Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity (2014) (348)
- Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1alpha: modulation by p38 MAPK. (2004) (326)
- Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP. (2010) (322)
- Activation of PPARgamma coactivator-1 through transcription factor docking. (1999) (304)
- O-GlcNAc Regulates FoxO Activation in Response to Glucose* (2008) (287)
- The cAMP/PKA pathway rapidly activates SIRT1 to promote fatty acid oxidation independently of changes in NAD(+). (2011) (284)
- Metabolic adaptations through the PGC-1 alpha and SIRT1 pathways. (2008) (283)
- TRPV4 Is a Regulator of Adipose Oxidative Metabolism, Inflammation, and Energy Homeostasis (2012) (282)
- Foxo1 integrates insulin signaling with mitochondrial function in the liver (2009) (277)
- Peroxisome proliferator-activated receptor gamma coactivator 1beta (PGC-1beta ), a novel PGC-1-related transcription coactivator associated with host cell factor. (2002) (275)
- Regulation of hepatic fasting response by PPARgamma coactivator-1alpha (PGC-1): requirement for hepatocyte nuclear factor 4alpha in gluconeogenesis. (2003) (260)
- Insulin regulation of gluconeogenesis (2018) (255)
- The deacetylase Sirt6 activates the acetyltransferase GCN5 and suppresses hepatic gluconeogenesis. (2012) (245)
- A metabolic prosurvival role for PML in breast cancer. (2012) (233)
- PGC-1β in the Regulation of Hepatic Glucose and Energy Metabolism* (2003) (220)
- Targeting hepatic glucose metabolism in the treatment of type 2 diabetes (2016) (209)
- Modulation of Estrogen Receptor-α Transcriptional Activity by the Coactivator PGC-1* (2000) (204)
- Cyclin D1-CDK4 Controls Glucose Metabolism Independently of Cell Cycle Progression (2014) (199)
- A Hypoxia-Induced Positive Feedback Loop Promotes Hypoxia-Inducible Factor 1α Stability through miR-210 Suppression of Glycerol-3-Phosphate Dehydrogenase 1-Like (2011) (192)
- The sirtuin family's role in aging and age-associated pathologies. (2013) (190)
- The genetic ablation of SRC-3 protects against obesity and improves insulin sensitivity by reducing the acetylation of PGC-1α (2008) (190)
- Nutrient-dependent regulation of PGC-1alpha's acetylation state and metabolic function through the enzymatic activities of Sirt1/GCN5. (2010) (186)
- Tissue-specific regulation of metabolic pathways through the transcriptional coactivator PGC1-α (2005) (181)
- A PGC-1α-O-GlcNAc Transferase Complex Regulates FoxO Transcription Factor Activity in Response to Glucose* (2009) (180)
- Mitochondrial biogenesis through activation of nuclear signaling proteins. (2013) (180)
- Molecular pathophysiology of hepatic glucose production. (2015) (179)
- Concurrent regulation of AMP-activated protein kinase and SIRT1 in mammalian cells. (2009) (166)
- PGC1α promotes tumor growth by inducing gene expression programs supporting lipogenesis. (2011) (162)
- A PGC1α-mediated transcriptional axis suppresses melanoma metastasis (2016) (155)
- ER and Nutrient Stress Promote Assembly of Respiratory Chain Supercomplexes through the PERK-eIF2α Axis. (2019) (154)
- Oleic Acid Stimulates Complete Oxidation of Fatty Acids through Protein Kinase A-dependent Activation of SIRT1-PGC1α Complex* (2013) (152)
- In vitro and in vivo induction of brown adipocyte uncoupling protein (thermogenin) by retinoic acid. (1996) (145)
- Tissue-specific regulation of metabolic pathways through the transcriptional coactivator PGC1-alpha. (2005) (137)
- Transcriptional activation of adipogenesis. (1999) (136)
- PGC-1beta in the regulation of hepatic glucose and energy metabolism. (2003) (131)
- Suppression of β Cell Energy Metabolism and Insulin Release by PGC-1α (2003) (129)
- GCN5-mediated Transcriptional Control of the Metabolic Coactivator PGC-1β through Lysine Acetylation* (2009) (128)
- Selective Chemical Inhibition of PGC-1α Gluconeogenic Activity Ameliorates Type 2 Diabetes (2017) (122)
- Cdc2-like kinase 2 is an insulin-regulated suppressor of hepatic gluconeogenesis. (2010) (114)
- Induction and degradation of the uncoupling protein thermogenin in brown adipocytes in vitro and in vivo. Evidence for a rapidly degradable pool. (1992) (109)
- Oxidative Dimerization of PHD2 is Responsible for its Inactivation and Contributes to Metabolic Reprogramming via HIF-1α Activation (2016) (105)
- SIRT 1 deacetylase protects against neurodegeneration in models for Alzheimer ’ s disease and amyotrophic lateral sclerosis (2013) (97)
- Yin Yang 1 deficiency in skeletal muscle protects against rapamycin-induced diabetic-like symptoms through activation of insulin/IGF signaling. (2012) (96)
- Modulation of estrogen receptor-alpha transcriptional activity by the coactivator PGC-1. (2000) (95)
- Regulation of adipogenesis and energy balance by PPARγ and PGC-1 (2000) (94)
- Genetic inhibition of hepatic acetyl-CoA carboxylase activity increases liver fat and alters global protein acetylationa (2014) (86)
- Suppression of beta cell energy metabolism and insulin release by PGC-1alpha. (2003) (82)
- Targeting mitochondrial oxidative metabolism in melanoma causes metabolic compensation through glucose and glutamine utilization. (2014) (79)
- Defective Mitochondrial Morphology and Bioenergetic Function in Mice Lacking the Transcription Factor Yin Yang 1 in Skeletal Muscle (2012) (78)
- Clk2 and B56β mediate insulin-regulated assembly of the PP2A phosphatase holoenzyme complex on Akt. (2011) (78)
- PGC-1 Coactivators: Shepherding the Mitochondrial Biogenesis of Tumors. (2016) (72)
- Hypothalamic malonyl-CoA triggers mitochondrial biogenesis and oxidative gene expression in skeletal muscle: Role of PGC-1α (2006) (67)
- Stimulation of uncoupling protein 1 expression in brown adipocytes by naturally occurring carotenoids (1999) (66)
- Foxa2, a novel transcriptional regulator of insulin sensitivity (2006) (58)
- Evidence for masking of brown adipose tissue mitochondrial GDP-binding sites in response to fasting in rats made obese by dietary manipulation. Effects of reversion to standard diet. (1991) (54)
- Characterization of the peroxisome proliferator activated receptor coactivator 1 alpha (PGC 1α) expression in the murine brain (2003) (51)
- Involvement of the retinoblastoma protein in brown and white adipocyte cell differentiation: functional and physical association with the adipogenic transcription factor C/EBPalpha. (1998) (50)
- Regulation of adipogenesis and energy balance by PPARgamma and PGC-1. (2000) (49)
- Defective NADPH production in mitochondrial disease complex I causes inflammation and cell death (2020) (49)
- Myopathy caused by mammalian target of rapamycin complex 1 (mTORC1) inactivation is not reversed by restoring mitochondrial function (2011) (43)
- Bromodomain Inhibitors Correct Bioenergetic Deficiency Caused by Mitochondrial Disease Complex I Mutations. (2016) (43)
- Effect of selective β-adrenoceptor stimulation on UCP synthesis in primary cultures of brown adipocytes (1996) (41)
- correction: CREB regulates hepatic gluconeogenesis through the coactivator PGC-1 (2001) (39)
- Retinoic acid modulates retinoid X receptor α and retinoic acid receptor α levels of cultured brown adipocytes (1997) (35)
- Brown Adipose YY1 Deficiency Activates Expression of Secreted Proteins Linked to Energy Expenditure and Prevents Diet-Induced Obesity (2015) (33)
- GCN5 ACETYLTRANSFERASE IN CELLULAR ENERGETIC AND METABOLIC PROCESSES. (2020) (32)
- USP7 attenuates hepatic gluconeogenesis through modulation of FoxO1 gene promoter occupancy. (2014) (30)
- A cold-stress-inducible PERK/OGT axis controls TOM70-assisted mitochondrial protein import and cristae formation. (2021) (30)
- Cancer Cells Hijack Gluconeogenic Enzymes to Fuel Cell Growth. (2015) (30)
- Cdc2-Like Kinase 2 Suppresses Hepatic Fatty Acid Oxidation and Ketogenesis Through Disruption of the PGC-1α and MED1 Complex (2014) (29)
- Adipose Tissue CLK2 Promotes Energy Expenditure during High-Fat Diet Intermittent Fasting. (2017) (27)
- The Methionine Transamination Pathway Controls Hepatic Glucose Metabolism through Regulation of the GCN5 Acetyltransferase and the PGC-1α Transcriptional Coactivator* (2016) (27)
- Retinoic acid modulates retinoid X receptor alpha and retinoic acid receptor alpha levels of cultured brown adipocytes. (1997) (26)
- Tetracyclines promote survival and fitness in mitochondrial disease models (2020) (26)
- 2-methoxyestradiol, an endogenous metabolite of 17b-estradiol, inhibits adipocyte proliferation (1998) (24)
- H3K27me3-mediated PGC1α gene silencing promotes melanoma invasion through WNT5A and YAP. (2020) (22)
- Inhibition of the ER stress IRE1α inflammatory pathway protects against cell death in mitochondrial complex I mutant cells (2018) (21)
- Cold exposure induces different uncoupling-protein thermogenin masking/unmasking processes in brown adipose tissue depending on mitochondrial subtypes. (1994) (20)
- ERRα Maintains Mitochondrial Oxidative Metabolism and Constitutes an Actionable Target in PGC1α-Elevated Melanomas (2017) (19)
- Cyclin D 1-CDK 4 Controls Glucose Metabolism Independently of Cell Cycle Progression (2014) (17)
- Certainly can't live without this: SIRT6. (2006) (16)
- Peroxisomal-derived ether phospholipids link nucleotides to respirasome assembly (2021) (15)
- Nutrient-dependent acetylation controls basic regulatory metabolic switches and cellular reprogramming. (2011) (14)
- Nuclear FoxO1 inflames insulin resistance (2010) (13)
- Transcriptome-wide analysis of PGC-1α–binding RNAs identifies genes linked to glucagon metabolic action (2020) (13)
- Mechanisms of mitochondrial respiratory adaptation (2022) (12)
- Obesity/Type 2 Diabetes-Associated Liver Tumors Are Sensitive to Cyclin D1 Deficiency (2020) (9)
- Erratum: CREB regulates hepatic gluconeogenesis through the coactivator PGC-1 (Nature (2001) 413 (179-183)) (2001) (8)
- Impaired starvation-induced loss of mitochondrial protein in the brown adipose tissue of dietary obese rats. (1992) (8)
- Decreased genetic dosage of hepatic Yin Yang 1 causes diabetic-like symptoms. (2014) (7)
- Glycine decarboxylase cleaves a "malignant" metabolic path to promote tumor initiation. (2012) (7)
- Stem cells: Dietary fat promotes intestinal dysregulation (2016) (6)
- Regulation of Hepatic Metabolism, Recent Advances, and Future Perspectives (2019) (6)
- Breaking BRAF(V600E)–drug resistance by stressing mitochondria (2016) (6)
- Autophagy mediates hepatic GRK2 degradation to facilitate glucagon‐induced metabolic adaptation to fasting (2020) (5)
- Hypersensitivity to ferroptosis in chromophobe RCC is mediated by a glutathione metabolic dependency and cystine import via solute carrier family 7 member 11 (2022) (5)
- A PGC‐1alpha:O‐GlcNAc Transferase Complex Regulates Foxo1a Activation in Response to Glucose (2007) (5)
- Adenosine activates thermogenic adipocytes (2014) (5)
- Diminished response to food deprivation of the rat brown adipose tissue mitochondrial uncoupling system with age (1997) (4)
- Insulin resistance: β-arrestin development (2009) (4)
- Receptor feasts on sugar and cholesterol (2007) (3)
- Targeting adaptive cellular responses to mitochondrial bioenergetic deficiencies in human disease (2021) (3)
- In vivo measurement of the acetylation state of sirtuin substrates as a proxy for sirtuin activity. (2013) (3)
- Chapter 7 – Signaling Transduction and Metabolomics (2018) (3)
- Tumor and Stem Cell Biology PGC 1 a Promotes Tumor Growth by Inducing Gene Expression Programs Supporting Lipogenesis (2011) (3)
- Inhibition of the ER stress IRE1α inflammatory pathway protects against cell death in mitochondrial complex I mutant cells (2018) (2)
- Dietary regulation of fasting-induced mitochondrial protein degradation in adult rat brown adipose tissue. (1992) (2)
- A hypoxia induced positive feedback loop promotes HIF-1 αααα stability through miR-210 suppression of glycerol-3-phosphate dehydrogenase 1-like (2011) (2)
- Elevated O‐GlcNAc Cycling on FOXO1A Mediates Inappropriate Hepatic Gluconeogenesis (2006) (1)
- Structure-Activity Relationship and Biological Investigation of SR18292 (16), a Suppressor of Glucagon-Induced Glucose Production. (2021) (1)
- 055 Tissue resident memory T cell survival requires exogenous lipid uptake and metabolism (2017) (1)
- A PGC‐1α:O‐GlcNAc Transferase Complex Regulates Foxo1a Activation in Response to Glucose (2008) (1)
- TITLE: Maintenance of Glucose Homeostasis through Acetylation of the Metabolic Transcriptional Coactivator PGC-1alpha PRINCIPAL INVESTIGATOR: (2007) (0)
- EFFECT OF SHORT- AND LONG-TERM ADRENERGIC STIMULATION ON THE EXPRESSION OF THE UNCOUPLING PROTEIN THERMOGENIN (UCP) IN BROWN ADIPOCYTE PRECURSOR CELLS DIFFERENTIATING IN CULTURE (1996) (0)
- Evolution and Disease Mitochondrial DNA Genetics and the Heteroplasmy Conundrum in (2014) (0)
- The SLC25A47 locus controls gluconeogenesis and energy expenditure (2023) (0)
- Abstract 279: Lysosomal cyst(e)ine regulates melanoma de-differentiation and sensitivity to ferroptosis (2023) (0)
- New pgc-1 isoforms and their uses (2002) (0)
- A Hypoxia-Induced Positive Feedback Loop Promotes Hypoxia-Inducible Factor 1α Stability through miR-210 Suppression of Glycerol-3-Phosphate Dehydrogenase 1-Like (2012) (0)
- A liver-specific mitochondrial carrier that controls gluconeogenesis and energy expenditure (2022) (0)
- Regulation of adipogenesis and energy balance by the PPARγ system. (2000) (0)
- Interrupting synoviolin play at the ER: a plausible action to elevate mitochondrial energetics and silence obesity (2015) (0)
- PGC-1, a novel PPAR-gamma coactivator OFF brown adipose tissue (1998) (0)
- Atossa: a royal link between OXPHOS metabolism and macrophage migration (2022) (0)
- 栄養素はPGC‐1α・SIRT1複合体を介してグルコース恒常性を調節する (2005) (0)
- Nutrient Sensing Through Metabolic Transcription‐Dependent Acetylation (2008) (0)
- Nicotinamide N-methyltransferase is a novel regulator of energy metabolism in adipose tissue (2014) (0)
- Defective NADPH production in mitochondrial disease complex I causes inflammation and cell death (2020) (0)
- PGC1a at the Nexus of Cancer Stem Cell Fates (2018) (0)
- Nuclear Chromatin Factors Defining Mitochondrial Bioenergetics (2012) (0)
- 81 Proffered Paper: Regulation of Cellular Metabolism by Cancer Genes – Implications in Breast Cancer (2012) (0)
- Tetracycline-dependent inhibition of mitoribosome protein elongation in mitochondrial disease mutant cells suppresses IRE1α to promote cell survival (2023) (0)
- Controversies surrounding peripheral cannabinoid receptor 1 in fatty liver disease. (2021) (0)
- Tetracyclines promote survival and fitness in mitochondrial disease models (2021) (0)
- Maintenance of Glucose Homeostasis Through Acetylation of the Metabolic Transcriptional Coactivator PGC1-alpha (2009) (0)
- Control of Nutrient and Energy Homeostasis through the PGC‐1 Pathway (2007) (0)
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What Schools Are Affiliated With Pere B. Puigserver?
Pere B. Puigserver is affiliated with the following schools:
