Peter C. Whybrow
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American psychiatrist
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Why Is Peter C. Whybrow Influential?
(Suggest an Edit or Addition)According to Wikipedia, Peter C. Whybrow is an English psychiatrist and award-winning author whose primary research focus has been on understanding the metabolic role of thyroid hormones in the adult brain and how to apply this knowledge to the treatment of mood disorder, especially bipolar disorder. He is Judson Braun Distinguished Professor in the Department of Psychiatry and Biobehavioral Sciences of the David Geffen School of Medicine at UCLA.
Peter C. Whybrow's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The National Depressive and Manic-depressive Association (DMDA) survey of bipolar members. (1994) (854)
- World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Unipolar Depressive Disorders, Part 1: Update 2013 on the acute and continuation treatment of unipolar depressive disorders (2013) (454)
- World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Unipolar Depressive Disorders in Primary Care (2007) (448)
- Independent assessment of manic and depressive symptoms by self-rating. Scale characteristics and implications for the study of mania. (1991) (395)
- A hypothesis of thyroid-catecholamine-receptor interaction. Its relevance to affective illness. (1981) (335)
- World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Unipolar Depressive Disorders, Part 1: Acute and Continuation Treatment of Major Depressive Disorder (2002) (333)
- Mental changes accompanying thyroid gland dysfunction. A reappraisal using objective psychological measurement. (1969) (329)
- Thyroid hormones, serotonin and mood: of synergy and significance in the adult brain (2002) (300)
- Abnormalities of indoleamines in affective disorders. (1972) (286)
- Rapid cycling bipolar affective disorder. I. Association with grade I hypothyroidism. (1990) (248)
- Rapid cycling bipolar affective disorder. II. Treatment of refractory rapid cycling with high-dose levothyroxine: a preliminary study. (1990) (245)
- The comparative antidepressant value of L-tryptophan and imipramine with and without attempted potentiation by liothyronine. (1972) (239)
- Evidence of chaotic mood variation in bipolar disorder. (1995) (236)
- Does thyroid supplementation accelerate tricyclic antidepressant response? A review and meta-analysis of the literature. (2001) (229)
- Reconceptualizing anhedonia: novel perspectives on balancing the pleasure networks in the human brain (2015) (176)
- World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Unipolar Depressive Disorders, Part 2: Maintenance treatment of major depressive disorder and treatment of chronic depressive disorders and subthreshold depressions. (2002) (168)
- Temporal relation between sleep and mood in patients with bipolar disorder. (2006) (167)
- Multisite data reanalysis of the validity of rapid cycling as a course modifier for bipolar disorder in DSM-IV. (1994) (144)
- World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Unipolar Depressive Disorders. Part 2: Maintenance Treatment of Major Depressive Disorder-Update 2015 (2015) (138)
- Supraphysiological doses of levothyroxine alter regional cerebral metabolism and improve mood in bipolar depression (2005) (133)
- Psychoneuroendocrinology of mood disorders. The hypothalamic-pituitary-thyroid axis. (1998) (121)
- Menstrual cycle related mood changes in women with bipolar disorder. (2003) (120)
- Dynamic coupling of whole-brain neuronal and neurotransmitter systems (2020) (118)
- Whole-Brain Multimodal Neuroimaging Model Using Serotonin Receptor Maps Explains Non-linear Functional Effects of LSD (2018) (117)
- Using technology to improve longitudinal studies: self-reporting with ChronoRecord in bipolar disorder. (2004) (108)
- Thyroid function and the response to liothyronine in depression. (1972) (103)
- Testing definitions of dysphoric mania and hypomania: prevalence, clinical characteristics and inter-episode stability. (1994) (96)
- Immune parameters in rapid cycling bipolar patients before and after lithium treatment. (1999) (93)
- Smartphones in mental health: a critical review of background issues, current status and future concerns (2020) (83)
- Gender differences in thyroid system function: relevance to bipolar disorder and its treatment (2014) (82)
- Psychosomatic medicine : current trends and clinical applications (1977) (80)
- Toward a biology of depression: some suggestions from neurophysiology. (1969) (80)
- Ethical perspectives on recommending digital technology for patients with mental illness (2017) (78)
- Thyroid, brain and mood modulation in affective disorder: insights from molecular research and functional brain imaging. (2003) (77)
- Absence of evidence for bornavirus infection in schizophrenia, bipolar disorder and major depressive disorder (2012) (76)
- MEMORY IMPROVEMENT WITH TREATMENT OF HYPOTHYROIDISM (2006) (68)
- Self-reporting software for bipolar disorder: Validation of ChronoRecord by patients with mania (2008) (63)
- X linkage revisited. A further family study of manic-depressive illness. (1974) (62)
- Measurement of tissue lithium concentration by lithium magnetic resonance spectroscopy in patients with bipolar disorder (1991) (60)
- Mood Disorders: Toward a New Psychobiology (1984) (59)
- Thyroid hypofunction in patients with rapid-cycling bipolar disorder after lithium challenge (2003) (58)
- Brightening Depression (2004) (56)
- I-123 iofetamine single-photon computed emission tomography in rapid cycling bipolar disorder: A clinical study (1997) (54)
- Sex-specific self-reported mood changes by patients with bipolar disorder. (2005) (51)
- Approximate entropy of self-reported mood prior to episodes in bipolar disorder. (2006) (51)
- The therapeutic use of triiodothyronine and high dose thyroxine in psychiatric disorder. (1994) (51)
- Subjective response to and tolerability of long-term supraphysiological doses of levothyroxine in refractory mood disorders. (2001) (50)
- Diretrizes da World Federation of Societies of Biological Psychiatry (WFSBP) Part 1: World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for biological treatment of unipolar depressive disorders, part I: Acute and continuation treatment of major depressive disorder (2009) (50)
- Melancholia, a Model in Madness: A Discussion of Recent Psychobiologic Research into Depressive Illness (1973) (48)
- Clinical hypothyroidism occurring during lithium treatment: two case histories and a review of thyroid function in 19 patients. (1971) (47)
- Relationship among latitude, climate, season and self-reported mood in bipolar disorder. (2009) (46)
- Big data for bipolar disorder (2016) (44)
- Supraphysiologic doses of levothyroxine as adjunctive therapy in bipolar depression: a randomized, double-blind, placebo-controlled study. (2014) (43)
- Relationship between sunlight and the age of onset of bipolar disorder: an international multisite study. (2014) (43)
- The electronic assessment of the longitudinal course of bipolar disorder: the ChronoRecord software. (2003) (42)
- Bone mineral density in pre-and post-menopausal women with affective disorder treated with long-term L-thyroxine augmentation. (2001) (42)
- Impact of sunlight on the age of onset of bipolar disorder (2012) (42)
- Verbal memory retrieval deficits associated with untreated hypothyroidism. (2007) (42)
- The transmission of manic depressive illness--II. Segregation analysis of three sets of family data. (1981) (41)
- The effect of changing thyroid function on cyclic affective illness in a human subject. (1986) (41)
- Cyclic A.M.P. in affective disorders. (1970) (40)
- Self-reported data from patients with bipolar disorder: frequency of brief depression. (2007) (38)
- Drug treatment patterns in bipolar disorder: analysis of long-term self-reported data (2013) (38)
- Bone mineral density and L-thyroxine treatment in rapidly cycling bipolar disorder (1997) (38)
- Levothyroxine effects on depressive symptoms and limbic glucose metabolism in bipolar disorder: a randomized, placebo-controlled positron emission tomography study (2015) (38)
- Influence of light exposure during early life on the age of onset of bipolar disorder. (2015) (35)
- American Mania: When More is Not Enough (2005) (35)
- Sex differences in thyroid axis function: Relevance to affective disorder and its treatment (1995) (33)
- Rapid Antidepressant Response After Nocturnal TRH Administration in Patients With Bipolar Type I and Bipolar Type II Major Depression (2005) (33)
- Online information seeking by patients with bipolar disorder: results from an international multisite survey (2016) (33)
- A family history study of rapid-cycling bipolar disorder (1993) (33)
- The potential influence of LED lighting on mental illness (2018) (32)
- Methysergide in mania. A controlled trial. (1969) (32)
- Mood changes related to antidepressants: a longitudinal study of patients with bipolar disorder in a naturalistic setting (2005) (32)
- Free T4 index and clinical outcome in patients with depression. (2007) (31)
- Influence of birth cohort on age of onset cluster analysis in bipolar I disorder (2015) (31)
- Association between age of onset and mood in bipolar disorder: comparison of subgroups identified by cluster analysis and clinical observation. (2010) (31)
- Adjunctive thyroid hormone treatment in rapid cycling bipolar disorder: A double‐blind placebo‐controlled trial of levothyroxine (L‐T4) and triiodothyronine (T3) (2018) (30)
- Frequency of subsyndromal symptoms and employment status in patients with bipolar disorder (2009) (30)
- Subsyndromal Mood Symptoms: A Useful Concept for Maintenance Studies of Bipolar Disorder? (2009) (29)
- Bone mineral density during maintenance treatment with supraphysiological doses of levothyroxine in affective disorders: a longitudinal study. (2004) (29)
- Changes in self-reported sleep duration predict mood changes in bipolar disorder. (2008) (26)
- Does the use of an automated tool for self-reporting mood by patients with bipolar disorder bias the collected data? (2005) (23)
- Thyroid Hormone, Brain, and Behavior (2002) (22)
- Comparison of sleep/wake parameters for self-monitoring bipolar disorder. (2009) (22)
- Association between solar insolation and a history of suicide attempts in bipolar I disorder. (2019) (22)
- Increasing Cybercrime Since the Pandemic: Concerns for Psychiatry (2021) (22)
- Lithium administration affects gene expression of thyroid hormone receptors in rat brain. (1999) (22)
- The association between concurrent psychotropic medications and self‐reported adherence with taking a mood stabilizer in bipolar disorder (2010) (22)
- Solar insolation in springtime influences age of onset of bipolar I disorder (2017) (21)
- Brief depressive symptoms in patients with bipolar disorder: Analysis of long-term self-reported data (2012) (20)
- Self-reported data from patients with bipolar disorder: impact on minimum episode length for hypomania. (2006) (20)
- Automation to optimise physician treatment of individual patients: examples in psychiatry. (2019) (20)
- Myxedema psychosis: clinical and biochemical changes during recovery. (1967) (18)
- Differential expression of thyroid hormone receptor isoforms by thyroid hormone and lithium in rat GH3 and B103 cells (1999) (18)
- Mood Charting and Technology: New Approach to Monitoring Patients with Mood Disorders (2006) (17)
- Decreasing the minimum length criterion for an episode of hypomania: evaluation using self-reported data from patients with bipolar disorder (2011) (17)
- Internet use by older adults with bipolar disorder: international survey results (2018) (15)
- Use of polypharmacy and self-reported mood in outpatients with bipolar disorder (2005) (15)
- Role of thyroid hormone therapy in depressive disorders (2021) (15)
- Hypothalamic–pituitary-end organ function in women with bipolar depression (2007) (15)
- Common use of dietary supplements for bipolar disorder: a naturalistic, self-reported study (2015) (15)
- Clinical applications of levothyroxine in refractory mood disorders (2003) (15)
- Disrupted brain structural connectivity in Pediatric Bipolar Disorder with psychosis (2019) (15)
- Trajectories of adherence to mood stabilizers in patients with bipolar disorder (2019) (15)
- Antidepressant dosage taken by patients with bipolar disorder: factors associated with irregularity (2013) (14)
- Regional cerebral glucose metabolism and anxiety symptoms in bipolar depression: Effects of levothyroxine (2010) (14)
- Regularity in Daily Mood Stabilizer Dosage Taken by Patients with Bipolar Disorder (2013) (13)
- Biology of depression and mania (1993) (13)
- Treatment of bipolar depression with supraphysiologic doses of levothyroxine: a randomized, placebo-controlled study of comorbid anxiety symptoms (2019) (12)
- Pituitary-adrenal and thyroid effects on melatonin content of the rat pineal gland (1989) (12)
- Effects of Peripheral Thyroid Hormones on the Central Nervous System: Relevance to Disorders of Mood (1988) (12)
- Spatiotemporal brain dynamics during recognition of the music of Johann Sebastian Bach (2020) (12)
- Biologische behandlung unipolarer depressiver störungen in der allgemeinärztlichen versorgung: Leitlinien der World Federation of Societies of Biological Psychiatry (WFSBP) (2008) (11)
- Comparison of pre-episode and pre-remission states using mood ratings from patients with bipolar disorder. (2011) (11)
- The Use and Abuse of the “Medical Model” as a Conceptual Frame in Psychiatry (1972) (11)
- Regularity of self-reported daily dosage of mood stabilizers and antipsychotics in patients with bipolar disorder (2018) (11)
- Thyroid hormone and mood modulation: New insights from functional brain imaging techniques (2003) (9)
- Effects of supraphysiological doses of l-thyroxine on cognitive function in healthy individuals (2002) (9)
- Association between median family income and self-reported mood symptoms in bipolar disorder. (2011) (8)
- X-linked transmission of manic-depressive illness. (1973) (8)
- Neuroendocrine Mediating Mechanisms: From the Symbolic Stimulus to the Physiological Response (1974) (8)
- World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Unipolar Depressive Disorders, Part 2: Maintenance Treatment of Major Depressive Disorder and Treatment of Chronic Depressive Disorders and Subthreshold Depressions (2002) (8)
- Variations in seasonal solar insolation are associated with a history of suicide attempts in bipolar I disorder (2021) (8)
- Antibodies in autoimmune thyroiditis affect glucose metabolism of anterior cingulate (2014) (7)
- Testing definitions of dysphoric mania and hypomania (1994) (7)
- Survey of psychiatrist use of digital technology in clinical practice (2020) (6)
- Adam Smith's American Dream: Time to Take Stock (2007) (6)
- Synergistic action between iodine and lithium. (1972) (6)
- International multi-site survey on the use of online support groups in bipolar disorder (2017) (5)
- Long-term treatment with supraphysiologic doses of levothyroxine in treatment-refractory mood disorders - A prospective study of cardiovascular tolerability. (2018) (5)
- Toward a Psychobiological Integration: Affective Illness as a Final Common Path to Adaptive Failure (1984) (5)
- Effects of hypothyroidism on brain metabolism and its associations with neuropsychiatric impairments (2006) (5)
- Commercial Use of Emotion Artificial Intelligence (AI): Implications for Psychiatry (2022) (4)
- Relationship between adjunctive medications for anxiety and time spent ill in patients with bipolar disorder (2009) (4)
- Hormones and Human Behavior (1987) (4)
- Mood and body weight in a woman with rapid cycling bipolar disorder: a case report. (1993) (4)
- What Is the 'Core' Symptom of Mania?-Reply (1993) (4)
- THYROID AXIS CONSIDERATIONS IN PATIENTS WITH RAPID CYCLING AFFECTIVE DISORDER (1992) (4)
- Depression, Mania, and Thyroid Function: A Story of Intimate Relationships (2008) (4)
- Special article Dangerously Addictive. Why we are biologically ill-suited to the riches of modern America? (2009) (4)
- Internet of things issues related to psychiatry (2021) (3)
- Implications for Clinical Practice, Training, and Research (1984) (3)
- The association between concurrent psychotropic medications and self-reported adherence with taking a mood stabilizer (2010) (3)
- A Mood Apart: The Thinker's Guide to Emotion and Its Disorders (1997) (3)
- New technology for longitudinal studies of patients with bipolar disorder (2005) (3)
- Erratum to: Online information seeking by patients with bipolar disorder: results from an international multisite survey (2017) (2)
- Receiver Operating Characteristic Curve Analysis of Screening Tools for Bipolar Disorder Comorbid With ADHD in Schoolchildren (2020) (2)
- Iatrogenic hypothyroid psychosis. (1969) (2)
- Depression and other psychiatric illnesses associated with medical conditions (1999) (2)
- Self-perpetuation of bromism. (1966) (2)
- Time Urgency, Sleep Loss, and Obesity (2012) (2)
- Changing Characteristics of Psychiatric Consultation in a University Hospital * (1969) (2)
- Correspondence (1997) (2)
- Diretrizes da World Federation of Societies of Biological Psychiatry (WFSBP) Part 2: World Federation of Societies of Biological Psychiatry (WFSBP)Part 2: Maintenance treatment af major depressive disorder and treatment of chronic depressive diosorders and subthreshold depressions (2009) (1)
- Mood Disorders: An Introduction (1984) (1)
- Lithium: a fascinating element in neuropsychiatry (2006) (1)
- Clinical and Familial Subtypes of Mood Disorders: Observation, Opinion, and Purpose (1984) (1)
- Association between Adherence with an Atypical Antipsychotic and with Other Psychiatric Drugs in Patients with Bipolar Disorder (2020) (1)
- Reply to the Letter to the Editor by George et al. (2014) (1)
- Association between polarity of first episode and solar insolation in bipolar I disorder. (2022) (1)
- A national policy for biomedical and behavioral research: position of the Association of American Medical Colleges. (1979) (1)
- Manic-Depressive Psychosis (1969) (1)
- Expectations for Artificial Intelligence (AI) in Psychiatry (2022) (1)
- Biological treatment of unipolar depressive disorders in the general practitioner's medical care: Guidelines of the World Federation of Societies of Biological Psychiatry (WFSBP) (2008) (1)
- Disrupted structural connectivity in Pediatric Bipolar Disorder (2017) (0)
- Die elektronische Erfassung des longitudinalen Verlaufs bipolarer Störungen (2008) (0)
- Depression and physical symptoms in primary hypothyroidism: Medial frontal cortical activity predicts individual therapeutic responses to thyroxine (2007) (0)
- The Emerging Neurobiology of Mood Disorder (1984) (0)
- Mood Disorders (1984) (0)
- Attachment and Loss (1984) (0)
- Supraphysiological doses of L-thyroxine alter regional cerebral metabolism in refractory bipolar depression: A FDG-PET study (2004) (0)
- New Journals (1998) (0)
- What is mental illness? toward a neuroscience of humanity (2000) (0)
- Mechanisms of the non-linear interactions between the neuronal and neurotransmitter systems explained by causal whole-brain modeling (2019) (0)
- TRICYCLIC DRUGS AND THE HYPOTHALAMIC-PITUITARY-THYROID AXIS (1980) (0)
- Clinical research training in psychopharmacology--context and climate: notes from the chairman's perspective. (1988) (0)
- A self-rating scale for mania: Preliminary findings (1989) (0)
- P.2.e.027 Supraphysiological doses of levothyroxine in bipolar depression: a randomised controlled, double blind study (2011) (0)
- In fl uence of light exposure during early life on the age of onset of bipolar disorder (2015) (0)
- Is More Always Better? The American Experiment (2013) (0)
- Preliminary communication Free T 4 index and clinical outcome in patients with depression (2007) (0)
- S.28.04 Ethical considerations about recommending technology for patients with bipolar illness (2017) (0)
- The Neurobiological Foundations of Behavior: Environmental Challenge and Response (1984) (0)
- Time, Thyroid and Psychosis (1979) (0)
- Depression (1964) (0)
- Chapter 2 Is More Always Better ? The American Experiment (2018) (0)
- Internal State Scale (2018) (0)
- Low-dimensional chaos in bipolar disorder [1] (multiple letters) (1998) (0)
- Do your patients with bipolar disorder use dietary supplements? (2015) (0)
- P-2-79 Endocrine response to lithium challenge in unmedicated rapid-cycling patients (1995) (0)
- WHAT IS THE CORE SYMPTOM OF MANIA ? AUTHOR'S REPLY (1993) (0)
- The Meaning of Loss: Psychoanalytic Explorations (1984) (0)
- Theoretical Aspects of Living Systems: Philosophical Pitfalls and Dynamic Constructs (1984) (0)
- Some thoughts upon the discontents of the British general practitioner. (1967) (0)
- Mood Disorders: Historical Perspective and Current Models of Explanation (1984) (0)
- Contents of the American Journal of Psychiatry (1994) (0)
- Depressive Disorders: Depression . Theory and Research. Joseph Becker. Winston, Washington, D.C., 1974 (distributor, Halsted [Wiley], New York). xii, 240 pp. $12.50. Series in Clinical Psychology. (1974) (0)
- Unconventional uses of thyroid hormones: Psychiatric indications in mood disorder (2002) (0)
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Peter C. Whybrow is affiliated with the following schools:
