Peter Elsbach
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Dutch physician
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Philosophy
Peter Elsbach's Degrees
- Doctorate Medicine University of Amsterdam
- PhD Medical Sciences Leiden University
Why Is Peter Elsbach Influential?
(Suggest an Edit or Addition)According to Wikipedia, Peter Elsbach was a Dutch physician. He was professor of medicine at the New York University School of Medicine. He specialized in biochemistry, infectious diseases and natural anti-bacterial host defense.
Peter Elsbach's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Purification and characterization of a potent bactericidal and membrane active protein from the granules of human polymorphonuclear leukocytes. (1978) (421)
- High-affinity binding of the bactericidal/permeability-increasing protein and a recombinant amino-terminal fragment to the lipid A region of lipopolysaccharide (1992) (251)
- Human bactericidal/permeability-increasing protein and a recombinant NH2-terminal fragment cause killing of serum-resistant gram-negative bacteria in whole blood and inhibit tumor necrosis factor release induced by the bacteria. (1992) (222)
- Role of the bactericidal/permeability-increasing protein in host defence. (1998) (215)
- The potent anti-Staphylococcus aureus activity of a sterile rabbit inflammatory fluid is due to a 14-kD phospholipase A2. (1996) (210)
- Separation and purification of a potent bactericidal/permeability-increasing protein and a closely associated phospholipase A2 from rabbit polymorphonuclear leukocytes. Observations on their relationship. (1979) (202)
- Cloning of the cDNA of a human neutrophil bactericidal protein. Structural and functional correlations. (1989) (199)
- Phospholipid metabolism by phagocytic cells. Phospholipases A2 associated with rabbit polymorphonuclear leukocyte granules. (1974) (195)
- Endotoxin-neutralizing properties of the 25 kD N-terminal fragment and a newly isolated 30 kD C-terminal fragment of the 55-60 kD bactericidal/permeability-increasing protein of human neutrophils (1991) (179)
- An opsonic function of the neutrophil bactericidal/permeability-increasing protein depends on both its N- and C-terminal domains. (1997) (152)
- A 25-kDa NH2-terminal fragment carries all the antibacterial activities of the human neutrophil 60-kDa bactericidal/permeability-increasing protein. (1987) (145)
- Bactericidal/permeability increasing protein and host defense against gram-negative bacteria and endotoxin. (1993) (137)
- Phospholipases and phospholipid turnover in Escherichia coli spheroplasts. (1972) (134)
- Low concentrations of indomethacin inhibit phospholipase A2 of rabbit polymorphonuclear leukocytes. (1978) (133)
- A reevaluation of the roles of the O2-dependent and O2-independent microbicidal systems of phagocytes. (1983) (128)
- The bactericidal/permeability-increasing protein (BPI), a potent element in host-defense against gram-negative bacteria and lipopolysaccharide. (1993) (126)
- Structural determinants of the action against Escherichia coli of a human inflammatory fluid phospholipase A2 in concert with polymorphonuclear leukocytes. (1994) (125)
- Purification of a cellular (granulocyte) and an extracellular (serum) phospholipase A2 that participate in the destruction of Escherichia coli in a rabbit inflammatory exudate. (1990) (124)
- What is the real role of antimicrobial polypeptides that can mediate several other inflammatory responses? (2003) (120)
- Lipopolysaccharide (LPS)-binding Proteins BPI and LBP Form Different Types of Complexes with LPS* (1997) (119)
- Structural and functional properties of a phospholipase A2 purified from an inflammatory exudate. (1986) (117)
- Resistance of gram-negative bacteria to purified bactericidal leukocyte proteins: relation to binding and bacterial lipopolysaccharide structure. (1980) (114)
- Separation of sublethal and lethal effects of the bactericidal/permeability increasing protein on Escherichia coli. (1990) (108)
- Bacterial lipopolysaccharide primes human neutrophils for enhanced release of arachidonic acid and causes phosphorylation of an 85-kD cytosolic phospholipase A2. (1994) (108)
- Cell-wall determinants of the bactericidal action of group IIA phospholipase A2 against Gram-positive bacteria. (1999) (103)
- Partial characterization and purification of a rabbit granulocyte factor that increases permeability of Escherichia coli. (1975) (100)
- Killing of gram-negative bacteria by polymorphonuclear leukocytes: role of an O2-independent bactericidal system. (1982) (99)
- Degradation of microorganisms by phagocytic cells. (1980) (93)
- Individual and synergistic effects of rabbit granulocyte proteins on Escherichia coli. (1994) (88)
- The role of lipopolysaccharides in the action of the bactericidal/permeability-increasing neutrophil protein on the bacterial envelope. (1984) (87)
- The Carboxyl-terminal Domain of Closely Related Endotoxin-binding Proteins Determines the Target of Protein-Lipopolysaccharide Complexes* (2002) (85)
- Extracellular accumulation of potently microbicidal bactericidal/permeability-increasing protein and p15s in an evolving sterile rabbit peritoneal inflammatory exudate. (1995) (80)
- Antibacterial 15-kDa protein isoforms (p15s) are members of a novel family of leukocyte proteins. (1993) (78)
- Human granulocytes express a 55-kDa lipopolysaccharide-binding protein on the cell surface that is identical to the bactericidal/permeability-increasing protein. (1993) (78)
- Isolation and characterization of a phospholipase A2 from an inflammatory exudate. (1978) (77)
- Innate immunity: from plants to humans. (2000) (75)
- Increased synthesis of phospholipid during phagocytosis. (1968) (73)
- Role of charge and hydrophobic interactions in the action of the bactericidal/permeability-increasing protein of neutrophils on gram-negative bacteria. (1983) (71)
- Antibacterial proteins of granulocytes differ in interaction with endotoxin. Comparison of bactericidal/permeability-increasing protein, p15s, and defensins. (1995) (70)
- Oxygen-independent intracellular and oxygen-dependent extracellular killing of Escherichia coli S15 by human polymorphonuclear leukocytes. (1985) (69)
- Phospholipid metabolism by phagocytic cells. I. A comparison of conversion of [32P]lysolecithin to lecithin and glycerylphosphorylcholine by homogenates of rabbit polymorphonuclear leukocytes and alveolar macrophages. (1966) (66)
- Effect of lipopolysaccharide (LPS) chain length on interactions of bactericidal/permeability-increasing protein and its bioactive 23-kilodalton NH2-terminal fragment with isolated LPS and intact Proteus mirabilis and Escherichia coli (1994) (65)
- Preferential binding of the neutrophil cytoplasmic granule-derived bactericidal/permeability increasing protein to target bacteria. Implications and use as a means of purification. (1989) (64)
- A recombinant amino terminal fragment of bactericidal/permeability‐increasing protein inhibits the induction of leukocyte responses by LPS (1993) (63)
- Phospholipase A activity associated with membranes of human polymorphonuclear leucocytes. (1977) (61)
- Separation of sublethal and lethal effects of polymorphonuclear leukocytes on Escherichia coli. (1990) (61)
- COMPOSITION AND SYNTHESIS OF LIPIDS IN RESTING AND PHAGOCYTIZING LEUKOCYTES (1959) (59)
- Utilization of labeled Escherichia coli as phospholipase substrate. (1991) (57)
- Integration of antimicrobial host defenses: role of the bactericidal/permeability-increasing protein. (1994) (56)
- THE INTERACTION IN VITRO BETWEEN POLYMORPHONUCLEAR LEUKOCYTES AND MYCOPLASMA (1971) (56)
- Some properties of phospholipases of alveolar macrophages. (1973) (56)
- Phospholipid metabolism by phagocytic cells. VI. Observations on the fate of phospholipids of granulocytes and ingested Escherichia coli during phagocytosis. (1972) (55)
- Bacterial phospholipid hydrolysis enhances the destruction of Escherichia coli ingested by rabbit neutrophils. Role of cellular and extracellular phospholipases. (1990) (54)
- On the interaction between phagocytes and micro-organisms. (1973) (54)
- ACID LIPASE AND PHOSPHOLIPASE ACTIVITY IN HOMOGENATES OF RABBIT POLYMORPHONUCLEAR LEUKOCYTES. (1963) (53)
- STUDIES ON THE SODIUM AND POTASSIUM TRANSPORT IN RABBIT POLYMORPHONUCLEAR LEUKOCYTES (1959) (53)
- Phagocytosis of bacteria and phospholipid degradation. (1988) (53)
- Effects of Phagocytosis by Rabbit Granulocytes on Macromolecular Synthesis and Degradation in Different Species of Bacteria (1973) (51)
- Metabolism of phospholipids by polymorphonuclear leukocytes. (1965) (51)
- Oxygen-dependent and oxygen-independent mechanisms of microbicidal activity of neutrophils. (1985) (50)
- Determinants of the action of phospholipases A on the envelope phospholipids of Escherichia coli. (1979) (49)
- Effect of ACTH, hydrocortisone, and glucagon on plasma nonesterified fatty acid concentration (NEFA) in normal subjects and in patients with liver disease. (1962) (44)
- Amino acid sequence of a basic Agkistrodon halys blomhoffii phospholipase A2. Possible role of NH2-terminal lysines in action on phospholipids of Escherichia coli. (1986) (43)
- Prospects for use of recombinant BPI in the treatment of gram-negative bacterial infections. (1995) (43)
- Deacylation of Lipopolysaccharide in Whole Escherichia coli during Destruction by Cellular and Extracellular Components of a Rabbit Peritoneal Inflammatory Exudate* (1999) (42)
- p15s (15-kD antimicrobial proteins) are stored in the secondary granules of Rabbit granulocytes: implications for antibacterial synergy with the bactericidal/permeability-increasing protein in inflammatory fluids. (1997) (42)
- Reversible envelope effects during and after killing of Escherichia coli w by a highly-purified rabbit polymorpho-nuclear leukocyte fraction. (1976) (42)
- Effects of levorphanol on phospholipid metabolism and composition in Escherichia coli. (1971) (41)
- Cellular triglyceride as a source of fatty acid for lecithin synthesis during phagocytosis. (1969) (40)
- Potent CD14-mediated signalling of human leukocytes by Escherichia coli can be mediated by interaction of whole bacteria and host cells without extensive prior release of endotoxin (1996) (38)
- Phospholipid metabolism by phagocytic cells. VII. The degradation and utilization of phospholipids of various microbial species by rabbit granulocytes. (1972) (37)
- Isolation of two isoforms of a novel 15-kDa protein from rabbit polymorphonuclear leukocytes that modulate the antibacterial actions of other leukocyte proteins. (1990) (36)
- Sensitivity of K1-Encapsulated Escherichia coli to Killing by the Bactericidal/Permeability-Increasing Protein of Rabbit and Human Neutrophils (1982) (36)
- The use of a phospholipase A-less Escherichia coli mutant to establish the action of granulocyte phospholipase A on bacterial phospholipids during killing by a highly purified granulocyte fraction. (1977) (36)
- Phospholipase A2 activity in the plasma membrane of human polymorphonuclear leukocytes (1981) (34)
- Phospholipase activity associated with serum albumin. (1973) (34)
- Host Defense Functions of Proteolytically Processed and Parent (Unprocessed) Cathelicidins of Rabbit Granulocytes (2002) (33)
- Phospholipid Synthesis by Staphylococcus aureus during (Sub)Lethal Attack by Mammalian 14-Kilodalton Group IIA Phospholipase A2 (2000) (32)
- Deacylation of Purified Lipopolysaccharides by Cellular and Extracellular Components of a Sterile Rabbit Peritoneal Inflammatory Exudate (1999) (31)
- The effects of the morphine analogue levorphanol on leukocytes. Metabolic effects at rest and during phagocytosis. (1971) (30)
- The appearance of lecithin- 32 P, synthesized from lysolecithin- 32 P, in phagosomes of polymorphonuclear leukocytes. (1972) (30)
- COMPARISON OF UPTAKE OF PALMITIC, STEARIC, OLEIC AND LINOLEIC ACID BY POLYMORPHONUCLEAR LEUKOCYTES. (1964) (29)
- Respiratory burst facilitates the digestion of Escherichia coli killed by polymorphonuclear leukocytes (1987) (29)
- The effect of restriction of protein and total calories on pancreatic function in obese patients. (1962) (28)
- The role of intramembrane Ca2+ in the hydrolysis of the phospholipids of Escherichia coli by Ca2+-dependent phospholipases. (1985) (28)
- Antibiotics from within: antibacterials from human and animal sources. (1990) (25)
- The antiinflammatory activity of analogs of indomethacin correlates with their inhibitory effects on phospholipase A2 of rabbit polymorphonuclear leukocytes. (1980) (25)
- Incorporation of [1-14C]linoleic acid into lipids of polymorphonuclear leukocytes (1963) (24)
- Persistence of Regulation of Macromolecular Synthesis by Escherichia coli During Killing by Disrupted Rabbit Granulocytes (1974) (24)
- UPTAKE OF FAT BY PHAGOCYTIC CELLS. AN EXAMINATION OF THE ROLE OF PHAGOCYTOSIS. II. RABBIT ALVEOLAR MACROPHAGES. (1965) (23)
- Salt and water metabolism during weight reduction. (1961) (23)
- Lysolecithin metabolism by human platelets. (1971) (23)
- Effects of the bactericidal/permeability-increasing protein of polymorphonuclear leukocytes on isolated bacterial cytoplasmic membrane vesicles (1988) (22)
- Relation between binding and the action of phospholipases A2 on Escherichia coli exposed to the bactericidal/permeability-increasing protein of neutrophils. (1987) (21)
- Metabolism of lysophosphatidyl ethanolamine and lysophosphatidyl choline by homogenates of rabbit polymorphonuclear leukocytes and alveolar macrophages. (1967) (21)
- Increased lecithin synthesis during phagocytosis by normal leukocytes and by leukocytes of a patient with chronic granulomatous disease. (1969) (21)
- The role of phospholipase A2 lysines in phospholipolysis of Escherichia coli killed by a membrane-active neutrophil protein. (1982) (20)
- Heparin inhibits phagocytosis by polymorphonuclear leukocytes (1981) (19)
- Acylation of monoacylglycerophosphoethanolamine in the inner and outer membranes of the envelope of an Escherichia coli K12 strain and its phospholipase A-deficient mutant. (1978) (19)
- The bactericidal/permeability increasing protein of neutrophils is a potent antibacterial and anti-endotoxin agent in vitro and in vivo. (1994) (19)
- The action of human and rabbit serum phospholipase A2 on Escherichia coli phospholipids. (1980) (19)
- Mechanisms of disposal of bacterial lipopolysaccharides by animal hosts. (2000) (18)
- Lipid metabolism by phagocytes. (1972) (18)
- UPTAKE OF FAT BY PHAGOCYTIC CELLS. AN EXAMINATION OF THE ROLE OF PHAGOCYTOSIS. I. RABBIT POLYMORPHONUCLEAR LEUKOCYTES. (1965) (18)
- Low concentrations of indomethacin inhibit phospholipase A 2 of rabbit polymorphonuclear leukocytes ( inflammation / prostaglandin synthesis (18)
- Effects of human and rabbit serum on viability, permeability, and envelope lipids of Serratia marcescens (1975) (17)
- Chylomicron-lipid-splitting activity in homogenates of rabbit polymorphonuclear leukocytes. (1965) (17)
- The effect of the morphine analog levorphanol on phagocytosing leukocytes. A morphologic study. (1971) (15)
- The activity of the pneumococcal autolytic system and the fate of the bacterium during ingestion by rabbit polymorphonuclear leukocytes (1977) (15)
- Altered Phospholipid Metabolism in Escherichia coli Accompanying Killing by Disrupted Granulocytes (1975) (13)
- Bactericidal/permeability-increasing protein in host defense and its efficacy in the treatment of bacterial sepsis (2001) (13)
- BPI (Bactericidal/Permeability-Increasing Protein) (2002) (13)
- Bactericidal permeability-increasing protein in host defence against gram-negative bacteria and endotoxin. (1994) (12)
- ACTH and cortisone as adjuncts in the treatment of advanced pulmonary tuberculosis. (1957) (11)
- Killing of Escherichia coli by a granulocyte fraction occurs without recognizable ultrastructural alterations in the bacterial envelope, as studied by freeze-fracture electron microscopy (1977) (10)
- The effect of collagenase preparations contaminated with phospholipase C activity on adipose tissue lecithin. (1970) (9)
- Role of Phagocytosis in the Uptake of Lipid by a Phagocytic Cell (1962) (9)
- Lecithin-lysolecithin cycle in the toad bladder. (1968) (8)
- Bactericidal/permeability-increasing protein in host defense and its efficacy in the treatment of bacterial sepsis (2001) (7)
- Chapter 6 – PHAGOCYTOSIS (1974) (7)
- Regulation and role of phospholipases in host-bacteria interaction. (1990) (6)
- Isolation and characterization of a phospholipase A, from an inflammatory exudate (1978) (6)
- Lipid Metabolism by Phagocytic Cells (1980) (5)
- Determinants of the Antimicrobial Action of 14-kD Phospholipase A2 (1997) (5)
- O2-independent killing of gram-negative bacteria by intact granulocytes. The role of a potent bactericidal membrane-perturbing protein. (1982) (4)
- Structural characterization of BPI-modulating 15 kDa proteins from rabbit polymorphonuclear leukocytes: Identification of a novel family of leukocyte proteins (2005) (4)
- Recent advances in therapy of sepsis: focus on recombinant bactericidal/permeability-increasing protein (BPI). (1998) (4)
- Lecithin and lysolecithin metabolism by isolated mucosal cells of the toad bladder. (1968) (4)
- Structural and functional organization of the human neutrophil 60 kDa bactericidal/permeability-increasing protein (1991) (4)
- Triglyceride formation and hydrolysis by toad bladder epithelium. (1969) (2)
- Killing of gram-negative bacteria by neutrophils: role of O2-independent system in intracellular killing and evidence of O2-dependent extracellular killing. (1985) (2)
- HEPARIN INHIBITION OF PHAGOCYTOSIS BY PMN 299 ulation of granulocyte function by hyaluronic acid (1)
- A connective tissue membrane as a molecular sieve. (1972) (1)
- Cardiac displacement in pectus excavatum. (1957) (1)
- The Role of Intramembrane Ca 2 + in the Hydrolysis of the Phospholipids of Escherichia coli by Ca 2 +-dependent Phospholipases * (2001) (1)
- Bactericidal/Permeability-Increasing Protein, p15s and Phospholipases A2, Endogenous Antibiotics in Host Defense Against Bacterial Infections (2020) (1)
- Oxygen-independent antimicrobial mechanisms of pmn (1999) (1)
- Two unidentified TABLE I Content and Composia . on of Lipids of Rabbit Polymorpkonudear Leukocytes (2003) (0)
- COOPERATIVE ACTION OF PURIFIED BACTERICIDAL/PERMEABILITY INCREASING PROTEIN AND PHOSPHOLIPASE A2 FROM RABBIT POLYMORPHONUCLEAR LEUKOCYTES (1980) (0)
- [DISORDERS IN WATER METABOLISM AND SALT METABOLISM IN OBESITY]. (1963) (0)
- Bactericidal/Permeability-Increasing Protein and Its Bioactive 23-Kilodalton NH2-Terminal Fragment with Isolated LPS (1993) (0)
- Recent Advances in Therapy of Sepsis (1998) (0)
- Biologically active bactericidal / permeability-increasing protein bruchstücke (1991) (0)
- Granulocyte Fraction Occurs Without Recognizable Ultrastructural Alterations (2003) (0)
- Lysolecithin Metabolism by Human Platelets BLOOD (2005) (0)
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