Peter G. Traber
American academic
Peter G. Traber's AcademicInfluence.com Rankings

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Philosophy
Peter G. Traber's Degrees
- Doctorate Medicine University of California, San Francisco
- Masters Business Administration Stanford University
Why Is Peter G. Traber Influential?
(Suggest an Edit or Addition)According to Wikipedia, Peter George Traber is an American pharmaceutical company executive. He is the Chief Medical Officer for Selecta Biosciences. https://selectabio.com/ He has been the president and chief executive officer of Baylor College of Medicine and the John and Clara Whitmore Professor of Medicine. Traber succeeded Ralph Feigin to become the fourth president of BCM in March 2003, and was president until November 2008. Prior to joining Baylor, he served as Senior Vice President for Clinical Development & Medical Affairs and Chief Medical Officer at GlaxoSmithKline. Prior to that, Traber held positions as Chief Executive Officer of the University of Pennsylvania Health System and interim Dean, Chair of the Department of Internal Medicine for the University of Pennsylvania School of Medicine, Chief of Gastroenterology at the University of Pennsylvania School of Medicine, and faculty member at the University of Michigan School of Medicine. He received his undergraduate degree B.S. in Chemical Engineering at the University of Michigan in 1977, his M.D. from Wayne State Medical School in Michigan in 1981, and he trained as a gastroenterologist, after completing an internal medicine residency at Northwestern University School of Medicine in Chicago.
Peter G. Traber's Published Works
Published Works
- Cdx1 and cdx2 expression during intestinal development. (2000) (583)
- An intestine-specific homeobox gene regulates proliferation and differentiation (1996) (518)
- A homeodomain protein related to caudal regulates intestine-specific gene transcription (1994) (435)
- Hepatocyte nuclear factor-1 alpha, GATA-4, and caudal related homeodomain protein Cdx2 interact functionally to modulate intestinal gene transcription. Implication for the developmental regulation of the sucrase-isomaltase gene. (2002) (245)
- Cancer in inflammatory bowel disease. (1994) (232)
- The mesenchymal winged helix transcription factor Fkh6 is required for the control of gastrointestinal proliferation and differentiation. (1997) (228)
- CDX1 protein expression in normal, metaplastic, and neoplastic human alimentary tract epithelium. (1997) (224)
- Regression of Fibrosis and Reversal of Cirrhosis in Rats by Galectin Inhibitors in Thioacetamide-Induced Liver Disease (2013) (183)
- Intestine-specific gene transcription. (1996) (171)
- Therapy of Experimental NASH and Fibrosis with Galectin Inhibitors (2013) (153)
- The Down Regulated in Adenoma (dra) Gene Encodes an Intestine-specific Membrane Sulfate Transport Protein (*) (1995) (150)
- Effects of Belapectin, an Inhibitor of Galectin-3, in Patients with Nonalcoholic Steatohepatitis With Cirrhosis And Portal Hypertension. (2019) (148)
- Electron microscopic evaluation of brain edema in rabbits with galactosamine‐induced fulminant hepatic failure: Ultrastructure and integrity of the blood‐brain barrier (1987) (143)
- Novel DNA-binding proteins regulate intestine-specific transcription of the sucrase-isomaltase gene (1992) (125)
- Randomised clinical study: GR‐MD‐02, a galectin‐3 inhibitor, vs. placebo in patients having non‐alcoholic steatohepatitis with advanced fibrosis (2016) (118)
- Induction of cytochrome P450IA genes (CYP1A) by omeprazole in the human alimentary tract. (1992) (116)
- Effect of body temperature on brain edema and encephalopathy in the rat after hepatic devascularization. (1989) (112)
- Hepatocyte nuclear factor-1 alpha (HNF-1 alpha) and HNF-1 beta regulate transcription via two elements in an intestine-specific promoter. (1994) (104)
- Isolation of intestinal epithelial cells for the study of differential gene expression along the crypt-villus axis. (1991) (98)
- Phosphorylation of the serine 60 residue within the Cdx2 activation domain mediates its transactivation capacity. (2001) (98)
- Regulation of sucrase-isomaltase gene expression along the crypt-villus axis of rat small intestine. (1990) (89)
- Vancomycin Ototoxicity in patient with normal renal function. (1981) (88)
- Sucrase-isomaltase gene expression along crypt-villus axis of human small intestine is regulated at level of mRNA abundance. (1992) (85)
- cis-Acting elements and transcription factors involved in the intestinal specific expression of the rat calbindin-D9K gene: binding of the intestine-specific transcription factor Cdx-2 to the TATA box. (1996) (85)
- Sucrase-isomaltase Gene Transcription Requires the Hepatocyte Nuclear Factor-1 (HNF-1) Regulatory Element and Is Regulated by the Ratio of HNF-1α to HNF-1β* (2001) (82)
- Activation of enhancer elements by the homeobox gene Cdx2 is cell line specific. (1997) (81)
- Transcriptional regulation of intestinal hydrolase biosynthesis during postnatal development in rats. (1994) (80)
- Brain edema in rabbits with galactosamine-induced fulminant hepatitis. Regional differences and effects on intracranial pressure. (1986) (76)
- Isolation and characterization of the human sucrase-isomaltase gene and demonstration of intestine-specific transcriptional elements. (1992) (73)
- Physiologic significance and regulation of hepatocellular heterogeneity. (1988) (71)
- The Caudal-related Homeodomain Protein Cdx1 Inhibits Proliferation of Intestinal Epithelial Cells by Down-regulation of D-type Cyclins* (2000) (71)
- Comparison of intestinal phospholipase A/lysophospholipase and sucrase-isomaltase genes suggest a common structure for enterocyte-specific promoters. (1997) (65)
- DNA Methylation Down-regulates CDX1 Gene Expression in Colorectal Cancer Cell Lines* (2002) (63)
- Expression of cytochrome P450b and P450e genes in small intestinal mucosa of rats following treatment with phenobarbital, polyhalogenated biphenyls, and organochlorine pesticides. (1988) (58)
- Cdx1 inhibits the proliferation of human colon cancer cells by reducing cyclin D1 gene expression (2003) (56)
- Binding of polysaccharides to human galectin-3 at a noncanonical site in its carbohydrate recognition domain. (2016) (53)
- Ammonia-induced swelling of rat cerebral cortical slices: Implications for the pathogenesis of brain edema in acute hepatic failure (1989) (50)
- Utility and variability of three non-invasive liver fibrosis imaging modalities to evaluate efficacy of GR-MD-02 in subjects with NASH and bridging fibrosis during a phase-2 randomized clinical trial (2018) (50)
- Expression of PRL-1 nuclear PTPase is associated with proliferation in liver but with differentiation in intestine. (1996) (49)
- Long‐term maintenance of the adult pattern of liver‐specific expression for P‐450b, P‐450e, albumin and α‐fetoprotein genes in intrasplenically transplanted hepatocytes (1990) (48)
- Regulation of lineage-specific transcription of the sucrase-isomaltase gene in transgenic mice and cell lines. (1995) (46)
- Demonstration by in situ hybridization of the zonal modulation of rat liver cytochrome P-450b and P-450e gene expression after phenobarbital. (1988) (45)
- Sucrase-isomaltase gene expression in Barrett's esophagus and adenocarcinoma. (1993) (45)
- Molecular pathogenesis of colorectal cancer. (1997) (44)
- The human sucrase-isomaltase gene directs complex patterns of gene expression in transgenic mice. (1993) (42)
- Clusterin gene transcription is activated by caudal-related homeobox genes in intestinal epithelium. (2001) (42)
- Developmental expression of SI is regulated in transgenic mice by an evolutionarily conserved promoter. (1997) (40)
- Galectins and disease implications for targeted therapeutics (2012) (34)
- Differentiation of intestinal epithelial cells: lessons from the study of intestine-specific gene expression. (1994) (33)
- A Novel Colonic Repressor Element Regulates Intestinal Gene Expression by Interacting with Cux/CDP (2002) (31)
- P450IIB gene expression in rat small intestine: cloning of intestinal P450IIB1 mRNA using the polymerase chain reaction and transcriptional regulation of induction. (1990) (29)
- Sucrase-isomaltase gene transcription requires the hepatocyte nuclear factor-1 (HNF-1) regulatory element and is regulated by the ratio of HNF-1 alpha to HNF-1 beta. (2001) (29)
- Expression and regulation of cytochrome P-450I genes (CYP1A1 and CYP1A2) in the rat alimentary tract. (1992) (27)
- Enhancing clinical and immunological effects of anti-PD-1 with belapectin, a galectin-3 inhibitor (2021) (24)
- Galectins in Disease and Potential Therapeutic Approaches (2012) (24)
- Differential regulation of cytochrome P-450 genes along rat intestinal crypt-villus axis. (1992) (24)
- Surviving Hurricane Katrina: reconstructing the educational enterprise of Tulane University School of Medicine. (2007) (23)
- Induction of P-450IIB genes within the rat liver acinus is not dependent on the chemical inducer or on the acinar organization. (1989) (22)
- cAMP Response Element-binding Protein Interacts with the Homeodomain Protein Cdx2 and Enhances Transcriptional Activity* (1999) (19)
- V. Transcriptional regulation, development, and neoplasia of the intestinal epithelium. (1997) (17)
- Brain Edema in Experimental Fulminant Hepatic Failure (1989) (17)
- Control of gene expression in intestinal epithelial cells. (1998) (16)
- Hepatocyte Nuclear Factor-1α, GATA-4, and Caudal Related Homeodomain Protein Cdx2 Interact Functionally to Modulate Intestinal Gene Transcription (2002) (16)
- Phenobarbital induction of cytochrome p‐450 b,e genes is dependent on protein synthesis (1988) (15)
- A multicenter, randomized, double-blind, PLB-controlled trial of Galectin-3 inhibitor (GR-MD-02) in patients with NASH cirrhosis and portal hypertension (2018) (14)
- Galectin-3 inhibition with belapectin combined with anti-OX40 therapy reprograms the tumor microenvironment to favor anti-tumor immunity (2021) (14)
- A phase 2a, open‐label pilot study of the galectin‐3 inhibitor GR‐MD‐02 for the treatment of moderate‐to‐severe plaque psoriasis (2017) (13)
- The effect of student- and teacher-centred small-group learning in medical school on knowledge acquisition, retention and application (1997) (11)
- Epithelial cell growth and differentiation. V. Transcriptional regulation, development, and neoplasia of the intestinal epithelium. (1997) (10)
- Murine intestinal disaccharidases: identification of structural variants of sucrase-isomaltase complex. (1993) (8)
- NF-κB blockade exacerbates experimental colitis in transgenic mice expressing an intestinal epithelial cell (IEC) specific IκB super-repressor (2001) (7)
- Detection of hepatitis C viral RNA by the polymerase chain reaction (1991) (7)
- Transcriptional Regulation in Intestinal Development (1999) (7)
- CREB-binding protein interacts with the homeo- domain protein Cdx2 and enhances transcriptional activity. (1999) (6)
- Transcriptional regulation in intestinal development. Implications for colorectal cancer. (1999) (4)
- CREB-binding [corrected] protein interacts with the homeodomain protein Cdx2 and enhances transcriptional activity. (1999) (4)
- Acinar localization of enzymes involved in biotransformation : analysis of the cytochrome P450 gene superfamily (1989) (3)
- Sucrase-isomaltase gene transcription requires both Cdx and HNF-1 regulatory sites and is modulated by the in vivo interaction between Cdx2 and HNF-1α proteins (2001) (2)
- Response from GlaxoSmithKline (2002) (2)
- Galectin - Method for Enhancing Specific Immunotherapies in Cancer Treatment (2018) (1)
- CDX1 is downregulated in colon cancer cells and expression inhibits growth (1998) (1)
- 1136 REGRESSION OF FIBROSIS AND REVERSAL OF CIRRHOSIS IN THIOACETAMIDE-INDUCED LIVER FIBROSIS FOLLOWING TREATMENT WITH GALECTIN INHIBITORS (2013) (1)
- Molecular mechanism of the heterogeneous induction of cytochrome p 450 by phenobarbital within the liver acinus a transcriptional event (1987) (1)
- Sucrase-isomaltase gene expression requires hepatocyte nuclear factor-1 DNA element during mouse intestinal development and is differentially modulated by HNF-1A and HNF-1B (2000) (1)
- Possible nizatidine-induced subfulminant hepatic failure. (1995) (1)
- Gut patterning: the case of the missing cecum. (1998) (1)
- P306 MORF-057, an oral selective α4β7 integrin inhibitor for Inflammatory Bowel Disease, leads to specific target engagement in a single and multiple ascending dose study in healthy subjects (2021) (1)
- Sa1686 Galectin-3 (Gal-3) Expression in Relation to Fibrosis in Nonalcoholic Fatty Liver Disease (NAFLD) and Nonalcoholic Steatohepatitis (NASH) (2014) (0)
- The homeodomain transcription factor Cdx1 reduces the growth of human colon cancer cells by altering cyclin D levels (2000) (0)
- Molecular and cell biology of the small intestine (1992) (0)
- DNA methylation downregulates CDX1 gene expression in a colon cancer cell line (2000) (0)
- Dual Role for Galectin-3 in CD8 T cell Function (2005) (0)
- Pulmonary hypertension and liver disease. (1988) (0)
- Phase 2 Dose-Finding Study in Patients with Gout Using SEL-212, a Novel PEGylated Uricase (SEL-037) Combined with Tolerogenic Nanoparticles (SEL-110). (2023) (0)
- 13C-Methacetin Breath Test accurately assesses clinically significant portal hypertension in patients with NASH cirrhosis (2017) (0)
- Phosphorylation of the Cdx2 activation domain is mediated by mitogen-activated protein kinase (2001) (0)
- Cathepsin L expression is modulated by GATA-4 and Cdx2 during intestinal epithelial cell differentiation (2003) (0)
- Retroviral mediated Cdx1 or Cdx2 expression in human colon cancer cell lines and the effects on cell growth (2001) (0)
- SSRIs and deliberate self-harm. Authors' reply (2002) (0)
- Sucrase-Isomaltase Gene Expression and Adenocarcinoma (1993) (0)
- News and notices (2005) (0)
- The intestine-specific homeobox gene CDX-2 regulates cell growth in intestinal cells (IEC-6) (1995) (0)
- Tu1283 PRECLINICAL CHARACTERIZATION OF AN ORAL SMALL MOLECULE INHIBITOR TARGETING THE INTEGRIN α4β7 FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASES (IBD) (2020) (0)
- GALECTIN-DIRECTED THERAPIES (2017) (0)
- The homeodomain transcription factor Cdx1 reduces the growth of human colon cancer cells by reducing G1 Cdk kinase activity and cyclin D1 expression (2001) (0)
- Identification of a novel DNA element involved in the colonic repression of the sucrase-isomaltase gene during mouse intestinal development (2000) (0)
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