Peter. J. Newman

Q: What Schools Are Affiliated With Peter. J. Newman

Peter. J. Newman is affiliated with the following schools: Medical College of Wisconsin, Dublin City University, Tel Aviv University, Rockefeller University, Case Western Reserve University, Gadjah Mada University, University of Reading

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Peter. J. Newman

Biology

#9851

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#13103

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Immunology

#598

World Rank

#618

Historical Rank

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Biology

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Peter. J. Newman's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

PECAM-1 (CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily. (1990) (981)
The biology of PECAM-1. (1997) (717)
Molecular and cellular properties of PECAM-1 (endoCAM/CD31): a novel vascular cell-cell adhesion molecule (1991) (684)
Integrins: dynamic scaffolds for adhesion and signaling in platelets. (2004) (592)
The human platelet alloantigens, PlA1 and PlA2, are associated with a leucine33/proline33 amino acid polymorphism in membrane glycoprotein IIIa, and are distinguishable by DNA typing. (1989) (540)
Platelet surface glycoproteins. Studies on resting and activated platelets and platelet membrane microparticles in normal subjects, and observations in patients during adult respiratory distress syndrome and cardiac surgery. (1986) (481)
Signal transduction pathways mediated by PECAM-1: new roles for an old molecule in platelet and vascular cell biology. (2003) (393)
CD31 expressed on distinctive T cell subsets is a preferential amplifier of beta 1 integrin-mediated adhesion (1992) (392)
Molecular and functional aspects of PECAM-1/CD31. (1994) (332)
Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31): alternatively spliced, functionally distinct isoforms expressed during mammalian cardiovascular development. (1994) (306)
Switched at birth: a new family for PECAM-1. (1999) (283)
Endothelial functions of platelet/endothelial cell adhesion molecule-1 (CD31) (2016) (252)
PECAM-1: regulator of endothelial junctional integrity (2014) (248)
Platelet PECAM-1 inhibits thrombus formation in vivo. (2006) (208)
Enzymatic amplification of platelet-specific messenger RNA using the polymerase chain reaction. (1988) (205)
The Protein-tyrosine Phosphatase SHP-2 Binds Platelet/Endothelial Cell Adhesion Molecule-1 (PECAM-1) and Forms a Distinct Signaling Complex during Platelet Aggregation (1997) (201)
The Neutrophil-specific Antigen CD177 Is a Counter-receptor for Platelet Endothelial Cell Adhesion Molecule-1 (CD31)* (2007) (195)
Individually Distinct Ig Homology Domains in PECAM-1 Regulate Homophilic Binding and Modulate Receptor Affinity (*) (1996) (189)
The molecular genetic basis of Glanzmann thrombasthenia in the Iraqi-Jewish and Arab populations in Israel. (1991) (181)
Platelet/endothelial cell adhesion molecule-1 (CD31)-mediated cellular aggregation involves cell surface glycosaminoglycans. (1993) (177)
Structure of the human gene encoding granule membrane protein-140, a member of the selectin family of adhesion receptors for leukocytes. (1990) (175)
Characterization of Phosphotyrosine Binding Motifs in the Cytoplasmic Domain of Platelet/Endothelial Cell Adhesion Molecule-1 (PECAM-1) That Are Required for the Cellular Association and Activation of the Protein-tyrosine Phosphatase, SHP-2* (1997) (173)
A new role for platelet-endothelial cell adhesion molecule-1 (CD31): inhibition of TCR-mediated signal transduction. (1999) (169)
PECAM-1: conflicts of interest in inflammation. (2010) (168)
Identification of FcgammaRIIa as the ITAM-bearing receptor mediating alphaIIbbeta3 outside-in integrin signaling in human platelets. (2008) (165)
On the association of glycoprotein Ib and actin-binding protein in human platelets (1985) (164)
Polymorphism of human platelet membrane glycoprotein IIb associated with the Baka/Bakb alloantigen system. (1990) (163)
Platelet endothelial cell adhesion molecule-1 serves as an inhibitory receptor that modulates platelet responses to collagen. (2001) (162)
The Role of PECAM‐1 in Vascular Cell Biology a (1994) (158)
A heterophilic adhesion mechanism for platelet/endothelial cell adhesion molecule 1 (CD31) (1992) (157)
Rapid determination of platelet alloantigen genotypes by polymerase chain reaction using allele‐specific primers (1994) (146)
Platelets release pathogenic serotonin and return to circulation after immune complex-mediated sequestration (2018) (144)
Anti-GPVI-associated ITP: an acquired platelet disorder caused by autoantibody-mediated clearance of the GPVI/FcRgamma-chain complex from the human platelet surface. (2004) (141)
Prenatal diagnosis of neonatal alloimmune thrombocytopenia using allele-specific oligonucleotide probes. (1991) (140)
Inhibition of antigen-receptor signaling by Platelet Endothelial Cell Adhesion Molecule-1 (CD31) requires functional ITIMs, SHP-2, and p56(lck). (2001) (135)
Activation-dependent changes in human platelet PECAM-1: phosphorylation, cytoskeletal association, and surface membrane redistribution (1992) (135)
PECAM-1 functions as a specific and potent inhibitor of mitochondrial-dependent apoptosis. (2003) (128)
Quantitation of membrane glycoprotein IIIa on intact human platelets using the monoclonal antibody, AP-3 (1985) (123)
Biosynthesis and processing of the cell adhesion molecule PECAM-1 includes production of a soluble form. (1994) (123)
The human platelet alloantigens Br(a) and Brb are associated with a single amino acid polymorphism on glycoprotein Ia (integrin subunit alpha 2). (1993) (120)
Antibodies Against the First Ig-Like Domain of Human Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1) That Inhibit PECAM-1-Dependent Homophilic Adhesion Block In Vivo Neutrophil Recruitment1 (2000) (117)
Endothelial cell PECAM-1 confers protection against endotoxic shock. (2005) (111)
Antibody to platelet/endothelial cell adhesion molecule-1 reduces myocardial infarct size in a rat model of ischemia-reperfusion injury. (1996) (109)
Truncation of the cytoplasmic domain of beta3 in a variant form of Glanzmann thrombasthenia abrogates signaling through the integrin alpha(IIb)beta3 complex. (1997) (109)
A point mutation in the cysteine-rich domain of glycoprotein (GP) IIIa results in the expression of a GPIIb-IIIa (alphaIIbbeta3) integrin receptor locked in a high-affinity state and a Glanzmann thrombasthenia-like phenotype. (2001) (108)
Site-Specific Effects of PECAM-1 on Atherosclerosis in LDL Receptor–Deficient Mice (2008) (106)
Heparin promotes platelet responsiveness by potentiating αIIbβ3-mediated outside-in signaling. (2011) (105)
Platelet/endothelial cell adhesion molecule-1 serves as a costimulatory agonist receptor that modulates integrin-dependent adhesion and aggregation of human platelets. (1998) (102)
Characterization of the human platelet/endothelial cell adhesion molecule-1 promoter: identification of a GATA-2 binding element required for optimal transcriptional activity. (1997) (101)
Platelet endothelial cell adhesion molecule (CD31). (1993) (96)
Characteristics of quinine- and quinidine-induced antibodies specific for platelet glycoproteins IIb and IIIa. (1991) (95)
Cooperative integrin/ITAM signaling in platelets enhances thrombus formation in vitro and in vivo. (2013) (93)
Organization of the gene for human platelet/endothelial cell adhesion molecule-1 shows alternatively spliced isoforms and a functionally complex cytoplasmic domain. (1994) (91)
Relative contribution of PECAM-1 adhesion and signaling to the maintenance of vascular integrity (2011) (89)
Glanzmann thrombasthenia: new insights from an historical perspective. (1994) (88)
Thrombospondin-1, a natural inhibitor of angiogenesis, regulates platelet-endothelial cell adhesion molecule-1 expression and endothelial cell morphogenesis. (1997) (87)
Identification of PECAM-1 in solid tumor cells and its potential involvement in tumor cell adhesion to endothelium. (1993) (86)
An amino acid polymorphism within the RGD binding domain of platelet membrane glycoprotein IIIa is responsible for the formation of the Pena/Penb alloantigen system. (1992) (86)
The molecular immunology of human platelet proteins. (1992) (84)
A single amino acid substitution flanking the fourth calcium binding domain of alpha IIb prevents maturation of the alpha IIb beta 3 integrin complex. (1994) (83)
Involvement of the cysteine-rich domain of glycoprotein IIIa in the expression of the human platelet alloantigen, PlA1: evidence for heterogeneity in the humoral response. (1995) (82)
Quantitation of membrane glycoprotein IIIa on intact human platelets using the monoclonal antibody, AP-3. (1985) (80)
Contributions of the extracellular and cytoplasmic domains of platelet-endothelial cell adhesion molecule-1 (PECAM-1/CD31) in regulating cell-cell localization. (2000) (80)
Glanzmann thrombasthenia resulting from a single amino acid substitution between the second and third calcium-binding domains of GPIIb. Role of the GPIIb amino terminus in integrin subunit association. (1995) (78)
Amino acid 489 is encoded by a mutational "hot spot" on the beta 3 integrin chain: the CA/TU human platelet alloantigen system. (1993) (78)
PECAM-1 negatively regulates GPIb/V/IX signaling in murine platelets. (2003) (78)
Identification and functional characterization of protein kinase C isozymes in platelets and HEL cells. (1992) (73)
Tests of the Extension and Deadbolt Models of Integrin Activation* (2007) (72)
Activation-independent, antibody-mediated removal of GPVI from circulating human platelets: development of a novel NOD/SCID mouse model to evaluate the in vivo effectiveness of anti-human platelet agents. (2006) (72)
Proteinase 3 Contributes to Transendothelial Migration of NB1-Positive Neutrophils (2012) (71)
A point mutation leads to an unpaired cysteine residue and a molecular weight polymorphism of a functional platelet beta 3 integrin subunit. The Sra alloantigen system of GPIIIa. (1994) (70)
Neutrophil Transmigration Mediated by the Neutrophil-Specific Antigen CD177 Is Influenced by the Endothelial S536N Dimorphism of Platelet Endothelial Cell Adhesion Molecule-1 (2010) (70)
Detection of drug‐dependent, platelet‐reactive antibodies by antigen‐ capture ELISA and flow cytometry (1990) (69)
Eptifibatide-induced thrombocytopenia and thrombosis in humans require FcgammaRIIa and the integrin beta3 cytoplasmic domain. (2009) (66)
Nomenclature of human platelet alloantigens: a problem with the HPA system? (1994) (65)
Human platelet alloantigens. (1994) (62)
Disruption of the long-range GPIIIa Cys5-Cys435 disulfide bond results in the production of constitutively active GPIIb-IIIa (αIIbβ3) integrin complexes (2002) (62)
Integrin Activation by Regulated Dimerization and Oligomerization of Platelet Endothelial Cell Adhesion Molecule (Pecam)-1 from within the Cell (2001) (61)
Synthesis by cultured human umbilical vein endothelial cells of two proteins structurally and immunologically related to platelet membrane glycoproteins IIb and IIIa (1986) (60)
The human PECAM1 gene maps to 17q23. (1996) (60)
Antiendothelial &agr;v&bgr;3 Antibodies Are a Major Cause of Intracranial Bleeding in Fetal/Neonatal Alloimmune Thrombocytopenia (2016) (55)
Synergistic action of two murine monoclonal antibodies that inhibit ADP-induced platelet aggregation without blocking fibrinogen binding. (1987) (55)
Platelet GPIIb-IIIa: Molecular Variations and Alloantigens (1991) (55)
A recombinant soluble form of the integrin alpha IIb beta 3 (GPIIb-IIIa) assumes an active, ligand-binding conformation and is recognized by GPIIb-IIIa-specific monoclonal, allo-, auto-, and drug-dependent platelet antibodies. (1998) (51)
Platelet hyperreactivity explains the bleeding abnormality and macrothrombocytopenia in a murine model of sitosterolemia. (2013) (51)
Cadherin 6 Has a Functional Role in Platelet Aggregation and Thrombus Formation (2012) (51)
GPIbα regulates platelet size by controlling the subcellular localization of filamin. (2012) (51)
Human Platelet Alloantigens: Recent Findings, New Perspectives (1995) (50)
Effect of single amino acid substitutions on the formation of the PlA and Bak alloantigenic epitopes (1991) (49)
Studies on the nature of the human platelet alloantigen, PlA1: localization to a 17,000-dalton polypeptide. (1985) (48)
Peroxynitrite reduces the endothelium-derived hyperpolarizing factor component of coronary flow-mediated dilation in PECAM-1-knockout mice. (2006) (46)
Inhibition of HPA-1a alloantibody-mediated platelet destruction by a deglycosylated anti-HPA-1a monoclonal antibody in mice: toward targeted treatment of fetal-alloimmune thrombocytopenia. (2013) (45)
A dinucleotide deletion results in defective membrane anchoring and circulating soluble glycoprotein Ib alpha in a novel form of Bernard-Soulier syndrome. (1997) (45)
Enzymatic amplification of specific cDNA inserts from λgt11 libraries (1988) (45)
Cellular and molecular aspects of PECAM-1. (1992) (44)
Lyn and PECAM-1 function as interdependent inhibitors of platelet aggregation. (2011) (43)
Structural basis for PECAM-1 homophilic binding. (2015) (43)
CRISPR/Cas9-mediated conversion of human platelet alloantigen allotypes. (2016) (43)
Human platelet fibrinogen: purification and hemostatic properties. (1985) (42)
Detection and characterization of monoclonal antibodies to platelet membrane proteins (1981) (41)
The proinflammatory phenotype of PECAM-1-deficient mice results in atherogenic diet-induced steatohepatitis. (2007) (41)
Residues within a lipid-associated segment of the PECAM-1 cytoplasmic domain are susceptible to inducible, sequential phosphorylation. (2011) (41)
Palmitoylation at Cys595 is essential for PECAM-1 localisation into membrane microdomains and for efficient PECAM-1-mediated cytoprotection (2006) (39)
Mechanisms of PECAM-1-mediated cytoprotection and implications for cancer cell survival (2005) (38)
Glanzmann's thrombasthenia associated with deletion-insertion and alternative splicing in the glycoprotein IIb gene. (1995) (38)
Detection of the Glanzmann's Thrombasthenia Mutations in Arab and Iraqi-Jewish Patients by Polymerase Chain Reaction and Restriction Analysis of Blood or Urine Samples (1991) (37)
The cell-adhesion and signaling molecule PECAM-1 is a molecular mediator of resistance to genotoxic chemotherapy (2006) (37)
Immunoreceptor tyrosine-based inhibitory motif (ITIM)-mediated inhibitory signaling is regulated by sequential phosphorylation mediated by distinct nonreceptor tyrosine kinases: a case study involving PECAM-1. (2013) (36)
Human platelets circulating in mice: applications for interrogating platelet function and survival, the efficacy of antiplatelet therapeutics, and the molecular basis of platelet immunological disorders (2007) (36)
The alleles of PECAM-1. (2006) (36)
Platelet alloantigens: cardiovascular as well as immunological risk factors? (1997) (35)
Neutrophil Proteinase 3 Acts on Protease-Activated Receptor-2 to Enhance Vascular Endothelial Cell Barrier Function (2013) (34)
Effect of single amino acid substitutions on the formation of the PlA and Bak alloantigenic epitopes. (1991) (34)
A Leu262Pro mutation in the integrin β3 subunit results in an αIIb-β3 complex that binds fibrin but not fibrinogen (2000) (34)
A Ser162→ Leu Mutation within Glycoprotein (GP) IIIa (Integrin β3) Results in an Unstable αIIbβ3 Complex that Retains Partial Function in a Novel Form of Type II Glanzmann Thrombasthenia (1998) (33)
Nitration of PECAM-1 ITIM tyrosines abrogates phosphorylation and SHP-2 binding. (2002) (33)
Reconstruction of platelet proteins into phospholipid vesicles. Functional proteoliposomes. (1985) (33)
Synthesis of analogs of human platelet membrane glycoprotein IIb-IIIa complex by chicken peripheral blood thrombocytes. (1985) (33)
Blockade of maternal anti‐HPA‐1a–mediated platelet clearance by an HPA‐1a epitope–specific F(ab′)2 in an in vivo mouse model of alloimmune thrombocytopenia (2009) (32)
Paxillin family members function as Csk-binding proteins that regulate Lyn activity in human and murine platelets. (2007) (32)
Cell Surface Glycosaminoglycans Do Not Serve as Ligands for PECAM-1 (1998) (31)
PTH Receptor Signaling in Osteoblasts Regulates Endochondral Vascularization in Maintenance of Postnatal Growth Plate (2015) (30)
Extraction and identification of human platelet integral membrane proteins using Triton X-114. (1982) (30)
Monoclonal antibodies bound to subunits of the integrin GPIIb-IIIa are internalized and interfere with filopodia formation and platelet aggregation. (1990) (29)
Neonatal alloimmune thrombocytopenia due to a new platelet-specific alloantibody. (1993) (28)
Platelet Activation and Thrombus Formation over IgG Immune Complexes Requires Integrin αIIbβ3 and Lyn Kinase (2015) (27)
Perspectives Series: Cell Adhesion in Vascular Biology The Biology of PECAM-1 (1996) (27)
Mechanism of Outside-In &agr;IIb&bgr;3-Mediated Activation of Human Platelets by the Colonizing Bacterium, Streptococcus gordonii* (2010) (26)
A site involving the "hybrid" and PSI homology domains of GPIIIa (beta 3-integrin subunit) is a common target for antibodies associated with quinine-induced immune thrombocytopenia. (2003) (26)
The Role of Sialylated Glycans in Human Platelet Endothelial Cell Adhesion Molecule 1 (PECAM-1)-mediated Trans Homophilic Interactions and Endothelial Cell Barrier Function* (2016) (26)
Disruption of the long-range GPIIIa Cys(5)-Cys(435) disulfide bond results in the production of constitutively active GPIIb-IIIa (alpha(IIb)beta(3)) integrin complexes. (2002) (26)
Regulation of Endothelial Cell Barrier Function by Antibody-driven Affinity Modulation of Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1)* (2014) (25)
Mapping early conformational changes in αIIb and β3 during biogenesis reveals a potential mechanism for αIIbβ3 adopting its bent conformation (2007) (25)
Changes in expression of the cell adhesion molecule PECAM-1 (CD31) during differentiation of human leukemic cell lines. (1994) (24)
The leukocyte cell adhesion cascade and its role in myocardial ischemia-reperfusion injury (1997) (22)
Drug-dependent clearance of human platelets in the NOD/scid mouse by antibodies from patients with drug-induced immune thrombocytopenia. (2010) (22)
A dinucleotide deletion in exon 4 of the PlA2 allelic form of glycoprotein IIIa: implications for the correlation of serologic versus genotypic analysis of human platelet alloantigens. (1996) (20)
PECAM-1 dampens cytokine levels during LPS-induced endotoxemia by regulating leukocyte trafficking. (2012) (19)
Reactive oxygen species induce reversible PECAM-1 tyrosine phosphorylation and SHP-2 binding. (2003) (18)
Disruption of a Long-Range Disulfide Bond Between Residues Cys406 and Cys655 in Glycoprotein IIIa Does Not Affect the Function of Platelet Glycoprotein IIb-IIIa (1997) (18)
Purification of human platelet membrane glycoproteins IIb and IIIa using high-performance liquid chromatography gel filtration. (1983) (18)
The role of fibrinogen A alpha chains in ADP-induced platelet aggregation in the presence of fibrinogen molecules containing gamma' chains. (1988) (17)
PECAM‐1 functions as a negative regulator of laminin‐induced platelet activation (2010) (16)
The cell-adhesion and signaling molecule PECAM-1 as a molecular mediator of genotoxic chemotherapy resistance (2005) (16)
Mapping early conformational changes in alphaIIb and beta3 during biogenesis reveals a potential mechanism for alphaIIbbeta3 adopting its bent conformation. (2007) (15)
Restoration of Responsiveness of Phospholipase Cγ2-Deficient Platelets by Enforced Expression of Phospholipase Cγ1 (2015) (15)
An alternatively spliced isoform of PECAM-1 is expressed at high levels in human and murine tissues, and suggests a novel role for the C-terminus of PECAM-1 in cytoprotective signaling (2008) (15)
Phospholipase Cγ2 contributes to stable thrombus formation on VWF (2004) (14)
The Anti-Inflammatory Actions of Platelet Endothelial Cell Adhesion Molecule-1 Do Not Involve Regulation of Endothelial Cell NF-κB (2010) (14)
Identification and characterization of functional cation coordination sites in platelet endothelial cell adhesion molecule-1. (1997) (14)
Adhesive and signaling properties of a naturally occurring allele of glycoprotein IIIa with an amino acid substitution within the ligand binding domain-the Pena/Penb platelet alloantigenic epitopes. (1998) (14)
Integrin-αIIbβ3-mediated outside-in signalling activates a negative feedback pathway to suppress platelet activation (2016) (14)
Packaging functionally important plasma proteins into the α‐granules of human‐induced pluripotent stem cell‐derived megakaryocytes (2019) (13)
Frontline Science: PECAM‐1 (CD31) expression in naïve and memory, but not acutely activated, CD8+ T cells (2018) (13)
A Leu262Pro mutation in the integrin beta(3) subunit results in an alpha(IIb)-beta(3) complex that binds fibrin but not fibrinogen. (2000) (11)
The biochemistry of platelet-specific alloantigens. (1986) (11)
High-resolution mapping of the polyclonal immune response to the human platelet alloantigen HPA-1a (PlA1). (2018) (11)
Inherited Mutations within the Calcium-Binding Sites of the Integrin αIIb Subunit (Platelet Glycoprotein IIb) (1996) (10)
Disruption of a long-range disulfide bond between residues Cys406 and Cys655 in glycoprotein IIIa does not affect the function of platelet glycoprotein IIb-IIIa. (1997) (10)
Identiﬁcation of Fc (cid:1) RIIa as the ITAM-bearing receptor mediating (cid:2) IIb (cid:3) 3 outside-in integrin signaling in human platelets (2008) (10)
A Frameshift Mutation at Gly975 in the Transmembrane Domain of GPIIb Prevents GPIIb-IIIa Expression – Analysis of Two Novel Mutations in a Kindred with Type I Glanzmann Thrombasthenia (1998) (10)
PECAM-1/IgG attenuates peroxynitrite-mediated extremity reperfusion injury. (2001) (10)
Bioengineered iPSC-derived megakaryocytes for the detection of platelet-specific patient alloantibodies. (2019) (9)
31 – SCREENING OF λgt11 LIBRARIES (1990) (9)
TCR-Mediated Signal Transduction Adhesion Molecule-1 (CD31): Inhibition of A New Role for Platelet-Endothelial Cell (1999) (9)
HPA-1a/b (PlA1/A2, Zwa/b): the odyssey of an alloantigen system (2007) (8)
Leukocyte adhesion in pial cerebral venules after PMA stimulation and ischemia/reperfusion in vivo. (1997) (8)
Hemizygosity for the gene encoding glycoprotein Ibβ is not responsible for macrothrombocytopenia and bleeding in patients with 22q11 deletion syndrome (2019) (7)
Inherited mutations within the calcium-binding sites of the integrin alpha IIb subunit (platelet glycoprotein IIb). Effects of the amino acid side chain and the amino acid position on cation binding. (1996) (7)
A Ser162-->Leu mutation within glycoprotein (GP) IIIa (integrin beta3) results in an unstable alphaIIbbeta3 complex that retains partial function in a novel form of type II Glanzmann thrombasthenia. (1998) (6)
Preclinical evaluation of immunotherapeutic regimens for fetal/neonatal alloimmune thrombocytopenia. (2021) (6)
Phospholipase Cgamma2 contributes to stable thrombus formation on VWF. (2004) (6)
Platelet Function Changes during Neonatal Cardiopulmonary Bypass Surgery: Mechanistic Basis and Lack of Correlation with Excessive Bleeding (2019) (6)
Molecular genetic aspects of human platelet antigen systems. (1991) (6)
Generation of ‘designer erythroblasts’ lacking one or more blood group systems from CRISPR/Cas9 gene‐edited human‐induced pluripotent stem cells (2021) (5)
CHAPTER 11 – PECAM-1 (2007) (5)
CRISPR‐mediated deletion of the PECAM‐1 cytoplasmic domain increases receptor lateral mobility and strengthens endothelial cell junctional integrity (2018) (4)
T cell receptor and alloimmune thrombocytopenias: a model for autoimmune diseases? (1992) (4)
Diacylglycerol kinase ζ is a negative regulator of GPVI-mediated platelet activation. (2019) (4)
Truncation of the Cytoplasmic Domain of (cid:98) 3 in a Variant Form of Glanzmann Thrombasthenia Abrogates Signaling through the Integrin (cid:97) IIb (cid:98) 3 Complex (1997) (4)
Generation of PECAM‐1 (CD31) conditional knockout mice (2019) (4)
New role for the GPVI/FcRγ chain complex (2006) (3)
Conditional CRISPR‐mediated deletion of Lyn kinase enhances differentiation and function of iPSC‐derived megakaryocytes (2021) (2)
Prophylactic administration of HPA-1a-specific antibodies prevents fetal/neonatal alloimmune thrombocytopenia in mice. (2022) (2)
Enzymatic amplification of specific cDNA inserts from lambda gt11 libraries. (1988) (2)
formation in vitro and in vivo Cooperative integrin/ITAM signaling in platelets enhances thrombus (2013) (2)
The FcR γ Chain Potentiates Outside-In Integrin Signaling. (2006) (2)
Cardiovascular-Kidney Interactions in Health and Disease Peroxynitrite reduces the endothelium-derived hyperpolarizing factor component of coronary flow-mediated dilation in PECAM-1-knockout mice (2005) (2)
filamin regulates platelet size by controlling the subcellular localization of α GPIb (2012) (2)
Overlapping and unique substrate specificities of ST3GAL1 and 2 during hematopoietic and megakaryocytic differentiation (2022) (2)
GPVI and the not so eager cleaver. (2010) (2)
Chapter 15 – PECAM-1 (2013) (2)
Cd31 pecam 1 is an adhesion amplifier on unique t cell subsets (1992) (2)
FcγRIIa Is Required for Outside-In β3 Integrin Signaling in Human Platelets. (2007) (2)
High-resolutionmapping of the polyclonal immune response to the human platelet alloantigen HPA-1a (Pl) (2018) (1)
Effect on ex vivo platelet aggregation and in vivo cyclic flow with Na+/H+ exchange inhibition (2011) (1)
The Anti-Inflammatory Actions of Platelet Endothelial Cell Adhesion Molecule-1 Do Not Involve Regulation of Endothelial Cell NF-kB (2010) (1)
Species-Specific Roles for a2,3- and a2,6-Linked Sialic Acid Residues in PECAM-1-Mediated Homophilic Interactions (2015) (1)
Filamins Regulate Differentiation of Megakaryocytes and Platelets From Cultured Embryonic Stem (ES) Cells. (2010) (1)
Prevention of Fetal/Neonatal Alloimmune Thrombocytopenia in Mice: Biochemical and Cell Biological Characterization of Isoforms of a Human Monoclonal Antibody (2022) (1)
Enhancement Of Endothelial Cell Barrier Function By Antibody-Driven Affinity Modulation Of PECAM-1 (2013) (1)
Construction and expression of an enzymatically active form of PECAM-1 containing the phosphatase domain of the protein tyrosine phosphatase, SHP-2. (2001) (1)
FcγRIIa Enhances Thrombus Growth in Vitro and in Vivo (2011) (1)
Atomic Level Dissection of the Platelet Endothelial Cell Adhesion Molecule 1 (PECAM-1) Homophilic Binding Interface: Implications for Endothelial Cell Barrier Function (2021) (1)
Polymorphism of human platelet membrane glycoprotein iiia and diagnostic and therapeutic applications thereof (1992) (1)
The HumanPlatelet Alloantigens Bra and Brb Are Associated with a Single Amino Acid Polymorphism on Glycoprotein la ( Integrin Subunit a 2 ) (2013) (1)
Neutrophil Proteinase 3 (PR3) Enhances Vascular Endothelial Cell Barrier Function (2010) (1)
High-resolution mapping of the polyclonal immune response to the human platelet alloantigen HPA-1a (Pl A1 ) (2018) (1)
Variability of PECAM-1 Expression on Blood Cells. (2004) (0)
Prophylactic Administration of Antibodies Specific for the HPA-1a Epitope Prevents Alloimmunization and Platelet Destruction in a Murine Model of Fetal Neonatal Alloimmune Thrombocytopenia (2021) (0)
Endothelial Biomedicine: Functions of Platelet-Endothelial Cell Adhesion Molecule-1 in the Vascular Endothelium (2007) (0)
Integrin αIIbβ3-Mediated Outside-in Signaling: Brake or Amplifier of Platelet Activation? (2014) (0)
GPIb (cid:1) regulates platelet size by controlling the subcellular localization of ﬁlamin (2012) (0)
Neither Free αIIb nor Free β3 Limits αIIbβ3 Biogenesis, and Pro-αIIbβ3 Adopts a Conformation Akin to Ligand-Bound Mature αIIbβ3. (2005) (0)
2008 Russell Ross Memorial Lectureship in Vascular Biology—Activating and Inhibitory Receptors in Blood and Vascular Cells (2008) (0)
PECAM-1: regulator of endothelial junctional integrity (2014) (0)
Designer Platelets: Crispr/Cas-Mediated Conversion of Human Platelet Alloantigen Allotypes (2014) (0)
THROMBOSIS AND HEMOSTASIS Cooperative integrin / ITAM signaling in platelets enhances thrombus formation in vitro and in vivo (2013) (0)
FcγRIIa and the Integrin β3 Cytoplasmic Domain: Two Prerequisites for Thrombocytopenia and Thrombosis Following Administration of the Fibrinogen Receptor Antagonist, Eptifibatide. (2007) (0)
The biology of PECAM-1. (1997) (0)
A Single Amino Acid Substitution Flanking the Fourth Calcium Binding Domain of aIm Prevents Maturation of the aImp, Integrin Complex* (2001) (0)
Adhesion Molecule-1 Dimorphism of Platelet Endothelial Cell N 536 Influenced by the Endothelial S Neutrophil-Specific Antigen CD177 Is Neutrophil Transmigration Mediated by the (2010) (0)
Platelet Activation In Sitosterolemia Mice (2010) (0)
Contribution of outside-in αIIbβ3-mediated activation of human platelets by the colonizing bacterium, Streptococcus gordonii, to the thrombotic complications of infective endocarditis (2010) (0)
the monoclonal antibody, AP-3 Quantitation of membrane glycoprotein IIIa on intact human platelets using (2011) (0)
alternative splicing in the glycoprotein IIb gene Glanzmann's thrombasthenia associated with deletion-insertion and (2011) (0)
PLATELETS AND THROMBOPOIESIS CRISPR / Cas 9-mediated conversion of human platelet alloantigen allotypes (2016) (0)
induced platelet aggregation without blocking fibrinogen binding Synergistic action of two murine monoclonal antibodies that inhibit ADP (2011) (0)
An Authentic Murine Model of Fetal/Neonatal Alloimmune Thrombocytopenia (2019) (0)
Scientific Sessions on Arteriosclerosis, Thrombosis and Vascular Biology (2010) (0)
Involve Regulation of Endothelial Cell NF-NotEndothelial Cell Adhesion Molecule-1 Do The Anti-Inflammatory Actions of Platelet Newman (2010) (0)
Glycoprotein IIb-IIIa in Glycoprotein IIIa Does Not Affect the Function of Platelet 655 Cys and 406 Disruption of a Long-Range Disulfide Bond Between Residues Cys (2011) (0)
An Unexpected Role For αIIbβ3 In Immune Complex Disorders (2013) (0)
Adhesive and Signaling Properties of a Naturally Occurring Allele of Glycoprotein IIIa With an Amino Acid Substitution Within the Ligand Binding Domain—The Pena/PenbPlatelet Alloantigenic Epitopes (1998) (0)
Migration of NB1-Positive Neutrophils Proteinase 3 Contributes to Transendothelial (0)
quinine-induced immune thrombocytopenia 3-integrin subunit) is a common target for antibodies associated with β A site involving the ''hybrid'' and PSI homology domains of GPIIIa ( (2013) (0)
Crispr/Cas9-Mediated Generation of Mouse Platelets Expressing the Human Platelet Alloantigen, HPA-1a (2015) (0)
CD4+ T Cells Are Required for Production of Disease-Causing Antibodies in an Alloantigen-Specific Murine Model of Fetal/Neonatal Alloimmune Thrombocytopenia (2022) (0)
Abstract 25: Platelet Activation by GPVI, GPIb-V-IX and aIIbß3 Requires PLC?2 but Not PLC?1 (2013) (0)
Blockade of Chemotherapy-Induced Thrombocytopenia by Bax Inhibiting Peptides (BIPs) in Mouse Model. (2007) (0)
Filamin A Controls Embryonic Stem Cell Differentiation. (2009) (0)
Block In Vivo Neutrophil Recruitment PECAM-1-Dependent Homophilic Adhesion Molecule-1 (PECAM-1) That Inhibit of Human Platelet Endothelial Cell Adhesion Antibodies Against the First Ig-Like Domain (1999) (0)
Neutrophil Proteinase (PR3) Regulates Neutrophil Transendothelial Cell Migration. (2010) (0)
Genetic Removal of Terminal Sialic Acid Residues from the O-Linked Glycans Adjacent to the HPA-9b Polymorphism of Platelet Membrane Glycoprotein IIb Improves the Binding and Detection of HPA-9b Patient Alloantibodies (2021) (0)
Involvement of the EGF Domain in the Formation of the Human Platelet Alloantigen, HPA-1a (2015) (0)
Conditional CRISPR-Mediated Deletion of Lyn Kinase Promotes Megakaryocyte Differentiation, Platelet Production and Function (2020) (0)
Abstract 40: Neutrophil Serine Protease PR3 Promotes Platelet Adhesion and Activation on von Willebrand Factor (vWF) Expressing Endothelial Cells (2013) (0)
Syndrome in a Novel Form of Bernard-Soulier α Circulating Soluble Glycoprotein Ib A Dinucleotide Deletion Results in Defective Membrane Anchoring and (2013) (0)
PECAM-1 Is a Negative Regulator of Platelet Activation by Laminin. (2007) (0)
Human Platelets Express Functional Pannexin-1 (2011) (0)
Crystal structure of PECAM-1 D1D2 domain (2016) (0)
Disaggregation Signals Initiated by Ligand Binding and Platelet Aggregation (2011) (0)
Atomic-Level Dissection of the Polyclonal Immune Response to the Human Platelet Alloantigen, HPA-1a (PlA1) (2018) (0)
FcγRIIa Rescues Normally-Poor αIIbβ3-Mediated Outside-in Signaling in Mouse Platelets. (2009) (0)
in the presence of fibrinogen molecules containing gamma' chains The role of fibrinogen A alpha chains in ADP-induced platelet aggregation (2011) (0)
Prevention of Fetal/Neonatal Alloimmune Thrombocytopenia in a Preclinical Model By Monoclonal Anti-HPA-1a Antibody Prophylaxis: Structural and Functional Properties of Antibody Variant Isoforms (2021) (0)
ATVB In Focus Platelet Activation and the Formation of the Platelet Plug (2010) (0)
Disruption of the long-range GPIIIa Cys 5 -Cys 435 disulﬁde bond results in the production of constitutively active GPIIb-IIIa ( (cid:1) IIb (cid:2) 3 ) integrin complexes (2002) (0)
Paxillin Becomes Tyrosine-Phosphorylated and Binds Csk in a GpIIb-IIIa-Dependent Manner Following GPVI-Induced Activation of Murine Platelets. (2004) (0)
Quantitative Measurement of VWF Binding to the Platelet Integrin αIIbβ3 - Abnormalities Identified in Individuals with VWD (2015) (0)
Generation of iPSC-Derived Human Megakaryocytes for Flow Cytometric Detection of Platelet-Specific Alloantibodies (2018) (0)
Reactive oxygen species induce reversible PECAM-1 tyrosine phosphorylation and SHP-2 binding : Vascular signaling by free radicals (2003) (0)
Patent Number : 45 ) Date of Patent : 5 , 436 , 163 Jul . 25 , 1995 (2017) (0)
The Neutrophil Specific CD177 Is a Novel Counter-Receptor for Endothelial PECAM-1. (2006) (0)
Drug Dependent Immune Destruction of Human Platelets in the NOD/SCID Mouse. (2008) (0)
PECAM-1 Inhibits Signaling Pathways That Amplify Platelet Aggregation. (2006) (0)

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