Peter. J. Newman
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(Suggest an Edit or Addition)Peter. J. Newman's Published Works
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Published Works
- PECAM-1 (CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily. (1990) (981)
- The biology of PECAM-1. (1997) (717)
- Molecular and cellular properties of PECAM-1 (endoCAM/CD31): a novel vascular cell-cell adhesion molecule (1991) (684)
- Integrins: dynamic scaffolds for adhesion and signaling in platelets. (2004) (592)
- The human platelet alloantigens, PlA1 and PlA2, are associated with a leucine33/proline33 amino acid polymorphism in membrane glycoprotein IIIa, and are distinguishable by DNA typing. (1989) (540)
- Platelet surface glycoproteins. Studies on resting and activated platelets and platelet membrane microparticles in normal subjects, and observations in patients during adult respiratory distress syndrome and cardiac surgery. (1986) (481)
- Signal transduction pathways mediated by PECAM-1: new roles for an old molecule in platelet and vascular cell biology. (2003) (393)
- CD31 expressed on distinctive T cell subsets is a preferential amplifier of beta 1 integrin-mediated adhesion (1992) (392)
- Molecular and functional aspects of PECAM-1/CD31. (1994) (332)
- Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31): alternatively spliced, functionally distinct isoforms expressed during mammalian cardiovascular development. (1994) (306)
- Switched at birth: a new family for PECAM-1. (1999) (283)
- Endothelial functions of platelet/endothelial cell adhesion molecule-1 (CD31) (2016) (252)
- PECAM-1: regulator of endothelial junctional integrity (2014) (248)
- Platelet PECAM-1 inhibits thrombus formation in vivo. (2006) (208)
- Enzymatic amplification of platelet-specific messenger RNA using the polymerase chain reaction. (1988) (205)
- The Protein-tyrosine Phosphatase SHP-2 Binds Platelet/Endothelial Cell Adhesion Molecule-1 (PECAM-1) and Forms a Distinct Signaling Complex during Platelet Aggregation (1997) (201)
- The Neutrophil-specific Antigen CD177 Is a Counter-receptor for Platelet Endothelial Cell Adhesion Molecule-1 (CD31)* (2007) (195)
- Individually Distinct Ig Homology Domains in PECAM-1 Regulate Homophilic Binding and Modulate Receptor Affinity (*) (1996) (189)
- The molecular genetic basis of Glanzmann thrombasthenia in the Iraqi-Jewish and Arab populations in Israel. (1991) (181)
- Platelet/endothelial cell adhesion molecule-1 (CD31)-mediated cellular aggregation involves cell surface glycosaminoglycans. (1993) (177)
- Structure of the human gene encoding granule membrane protein-140, a member of the selectin family of adhesion receptors for leukocytes. (1990) (175)
- Characterization of Phosphotyrosine Binding Motifs in the Cytoplasmic Domain of Platelet/Endothelial Cell Adhesion Molecule-1 (PECAM-1) That Are Required for the Cellular Association and Activation of the Protein-tyrosine Phosphatase, SHP-2* (1997) (173)
- A new role for platelet-endothelial cell adhesion molecule-1 (CD31): inhibition of TCR-mediated signal transduction. (1999) (169)
- PECAM-1: conflicts of interest in inflammation. (2010) (168)
- Identification of FcgammaRIIa as the ITAM-bearing receptor mediating alphaIIbbeta3 outside-in integrin signaling in human platelets. (2008) (165)
- On the association of glycoprotein Ib and actin-binding protein in human platelets (1985) (164)
- Polymorphism of human platelet membrane glycoprotein IIb associated with the Baka/Bakb alloantigen system. (1990) (163)
- Platelet endothelial cell adhesion molecule-1 serves as an inhibitory receptor that modulates platelet responses to collagen. (2001) (162)
- The Role of PECAM‐1 in Vascular Cell Biology a (1994) (158)
- A heterophilic adhesion mechanism for platelet/endothelial cell adhesion molecule 1 (CD31) (1992) (157)
- Rapid determination of platelet alloantigen genotypes by polymerase chain reaction using allele‐specific primers (1994) (146)
- Platelets release pathogenic serotonin and return to circulation after immune complex-mediated sequestration (2018) (144)
- Anti-GPVI-associated ITP: an acquired platelet disorder caused by autoantibody-mediated clearance of the GPVI/FcRgamma-chain complex from the human platelet surface. (2004) (141)
- Prenatal diagnosis of neonatal alloimmune thrombocytopenia using allele-specific oligonucleotide probes. (1991) (140)
- Inhibition of antigen-receptor signaling by Platelet Endothelial Cell Adhesion Molecule-1 (CD31) requires functional ITIMs, SHP-2, and p56(lck). (2001) (135)
- Activation-dependent changes in human platelet PECAM-1: phosphorylation, cytoskeletal association, and surface membrane redistribution (1992) (135)
- PECAM-1 functions as a specific and potent inhibitor of mitochondrial-dependent apoptosis. (2003) (128)
- Quantitation of membrane glycoprotein IIIa on intact human platelets using the monoclonal antibody, AP-3 (1985) (123)
- Biosynthesis and processing of the cell adhesion molecule PECAM-1 includes production of a soluble form. (1994) (123)
- The human platelet alloantigens Br(a) and Brb are associated with a single amino acid polymorphism on glycoprotein Ia (integrin subunit alpha 2). (1993) (120)
- Antibodies Against the First Ig-Like Domain of Human Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1) That Inhibit PECAM-1-Dependent Homophilic Adhesion Block In Vivo Neutrophil Recruitment1 (2000) (117)
- Endothelial cell PECAM-1 confers protection against endotoxic shock. (2005) (111)
- Antibody to platelet/endothelial cell adhesion molecule-1 reduces myocardial infarct size in a rat model of ischemia-reperfusion injury. (1996) (109)
- Truncation of the cytoplasmic domain of beta3 in a variant form of Glanzmann thrombasthenia abrogates signaling through the integrin alpha(IIb)beta3 complex. (1997) (109)
- A point mutation in the cysteine-rich domain of glycoprotein (GP) IIIa results in the expression of a GPIIb-IIIa (alphaIIbbeta3) integrin receptor locked in a high-affinity state and a Glanzmann thrombasthenia-like phenotype. (2001) (108)
- Site-Specific Effects of PECAM-1 on Atherosclerosis in LDL Receptor–Deficient Mice (2008) (106)
- Heparin promotes platelet responsiveness by potentiating αIIbβ3-mediated outside-in signaling. (2011) (105)
- Platelet/endothelial cell adhesion molecule-1 serves as a costimulatory agonist receptor that modulates integrin-dependent adhesion and aggregation of human platelets. (1998) (102)
- Characterization of the human platelet/endothelial cell adhesion molecule-1 promoter: identification of a GATA-2 binding element required for optimal transcriptional activity. (1997) (101)
- Platelet endothelial cell adhesion molecule (CD31). (1993) (96)
- Characteristics of quinine- and quinidine-induced antibodies specific for platelet glycoproteins IIb and IIIa. (1991) (95)
- Cooperative integrin/ITAM signaling in platelets enhances thrombus formation in vitro and in vivo. (2013) (93)
- Organization of the gene for human platelet/endothelial cell adhesion molecule-1 shows alternatively spliced isoforms and a functionally complex cytoplasmic domain. (1994) (91)
- Relative contribution of PECAM-1 adhesion and signaling to the maintenance of vascular integrity (2011) (89)
- Glanzmann thrombasthenia: new insights from an historical perspective. (1994) (88)
- Thrombospondin-1, a natural inhibitor of angiogenesis, regulates platelet-endothelial cell adhesion molecule-1 expression and endothelial cell morphogenesis. (1997) (87)
- Identification of PECAM-1 in solid tumor cells and its potential involvement in tumor cell adhesion to endothelium. (1993) (86)
- An amino acid polymorphism within the RGD binding domain of platelet membrane glycoprotein IIIa is responsible for the formation of the Pena/Penb alloantigen system. (1992) (86)
- The molecular immunology of human platelet proteins. (1992) (84)
- A single amino acid substitution flanking the fourth calcium binding domain of alpha IIb prevents maturation of the alpha IIb beta 3 integrin complex. (1994) (83)
- Involvement of the cysteine-rich domain of glycoprotein IIIa in the expression of the human platelet alloantigen, PlA1: evidence for heterogeneity in the humoral response. (1995) (82)
- Quantitation of membrane glycoprotein IIIa on intact human platelets using the monoclonal antibody, AP-3. (1985) (80)
- Contributions of the extracellular and cytoplasmic domains of platelet-endothelial cell adhesion molecule-1 (PECAM-1/CD31) in regulating cell-cell localization. (2000) (80)
- Glanzmann thrombasthenia resulting from a single amino acid substitution between the second and third calcium-binding domains of GPIIb. Role of the GPIIb amino terminus in integrin subunit association. (1995) (78)
- Amino acid 489 is encoded by a mutational "hot spot" on the beta 3 integrin chain: the CA/TU human platelet alloantigen system. (1993) (78)
- PECAM-1 negatively regulates GPIb/V/IX signaling in murine platelets. (2003) (78)
- Identification and functional characterization of protein kinase C isozymes in platelets and HEL cells. (1992) (73)
- Tests of the Extension and Deadbolt Models of Integrin Activation* (2007) (72)
- Activation-independent, antibody-mediated removal of GPVI from circulating human platelets: development of a novel NOD/SCID mouse model to evaluate the in vivo effectiveness of anti-human platelet agents. (2006) (72)
- Proteinase 3 Contributes to Transendothelial Migration of NB1-Positive Neutrophils (2012) (71)
- A point mutation leads to an unpaired cysteine residue and a molecular weight polymorphism of a functional platelet beta 3 integrin subunit. The Sra alloantigen system of GPIIIa. (1994) (70)
- Neutrophil Transmigration Mediated by the Neutrophil-Specific Antigen CD177 Is Influenced by the Endothelial S536N Dimorphism of Platelet Endothelial Cell Adhesion Molecule-1 (2010) (70)
- Detection of drug‐dependent, platelet‐reactive antibodies by antigen‐ capture ELISA and flow cytometry (1990) (69)
- Eptifibatide-induced thrombocytopenia and thrombosis in humans require FcgammaRIIa and the integrin beta3 cytoplasmic domain. (2009) (66)
- Nomenclature of human platelet alloantigens: a problem with the HPA system? (1994) (65)
- Human platelet alloantigens. (1994) (62)
- Disruption of the long-range GPIIIa Cys5-Cys435 disulfide bond results in the production of constitutively active GPIIb-IIIa (αIIbβ3) integrin complexes (2002) (62)
- Integrin Activation by Regulated Dimerization and Oligomerization of Platelet Endothelial Cell Adhesion Molecule (Pecam)-1 from within the Cell (2001) (61)
- Synthesis by cultured human umbilical vein endothelial cells of two proteins structurally and immunologically related to platelet membrane glycoproteins IIb and IIIa (1986) (60)
- The human PECAM1 gene maps to 17q23. (1996) (60)
- Antiendothelial &agr;v&bgr;3 Antibodies Are a Major Cause of Intracranial Bleeding in Fetal/Neonatal Alloimmune Thrombocytopenia (2016) (55)
- Synergistic action of two murine monoclonal antibodies that inhibit ADP-induced platelet aggregation without blocking fibrinogen binding. (1987) (55)
- Platelet GPIIb-IIIa: Molecular Variations and Alloantigens (1991) (55)
- A recombinant soluble form of the integrin alpha IIb beta 3 (GPIIb-IIIa) assumes an active, ligand-binding conformation and is recognized by GPIIb-IIIa-specific monoclonal, allo-, auto-, and drug-dependent platelet antibodies. (1998) (51)
- Platelet hyperreactivity explains the bleeding abnormality and macrothrombocytopenia in a murine model of sitosterolemia. (2013) (51)
- Cadherin 6 Has a Functional Role in Platelet Aggregation and Thrombus Formation (2012) (51)
- GPIbα regulates platelet size by controlling the subcellular localization of filamin. (2012) (51)
- Human Platelet Alloantigens: Recent Findings, New Perspectives (1995) (50)
- Effect of single amino acid substitutions on the formation of the PlA and Bak alloantigenic epitopes (1991) (49)
- Studies on the nature of the human platelet alloantigen, PlA1: localization to a 17,000-dalton polypeptide. (1985) (48)
- Peroxynitrite reduces the endothelium-derived hyperpolarizing factor component of coronary flow-mediated dilation in PECAM-1-knockout mice. (2006) (46)
- Inhibition of HPA-1a alloantibody-mediated platelet destruction by a deglycosylated anti-HPA-1a monoclonal antibody in mice: toward targeted treatment of fetal-alloimmune thrombocytopenia. (2013) (45)
- A dinucleotide deletion results in defective membrane anchoring and circulating soluble glycoprotein Ib alpha in a novel form of Bernard-Soulier syndrome. (1997) (45)
- Enzymatic amplification of specific cDNA inserts from λgt11 libraries (1988) (45)
- Cellular and molecular aspects of PECAM-1. (1992) (44)
- Lyn and PECAM-1 function as interdependent inhibitors of platelet aggregation. (2011) (43)
- Structural basis for PECAM-1 homophilic binding. (2015) (43)
- CRISPR/Cas9-mediated conversion of human platelet alloantigen allotypes. (2016) (43)
- Human platelet fibrinogen: purification and hemostatic properties. (1985) (42)
- Detection and characterization of monoclonal antibodies to platelet membrane proteins (1981) (41)
- The proinflammatory phenotype of PECAM-1-deficient mice results in atherogenic diet-induced steatohepatitis. (2007) (41)
- Residues within a lipid-associated segment of the PECAM-1 cytoplasmic domain are susceptible to inducible, sequential phosphorylation. (2011) (41)
- Palmitoylation at Cys595 is essential for PECAM-1 localisation into membrane microdomains and for efficient PECAM-1-mediated cytoprotection (2006) (39)
- Mechanisms of PECAM-1-mediated cytoprotection and implications for cancer cell survival (2005) (38)
- Glanzmann's thrombasthenia associated with deletion-insertion and alternative splicing in the glycoprotein IIb gene. (1995) (38)
- Detection of the Glanzmann's Thrombasthenia Mutations in Arab and Iraqi-Jewish Patients by Polymerase Chain Reaction and Restriction Analysis of Blood or Urine Samples (1991) (37)
- The cell-adhesion and signaling molecule PECAM-1 is a molecular mediator of resistance to genotoxic chemotherapy (2006) (37)
- Immunoreceptor tyrosine-based inhibitory motif (ITIM)-mediated inhibitory signaling is regulated by sequential phosphorylation mediated by distinct nonreceptor tyrosine kinases: a case study involving PECAM-1. (2013) (36)
- Human platelets circulating in mice: applications for interrogating platelet function and survival, the efficacy of antiplatelet therapeutics, and the molecular basis of platelet immunological disorders (2007) (36)
- The alleles of PECAM-1. (2006) (36)
- Platelet alloantigens: cardiovascular as well as immunological risk factors? (1997) (35)
- Neutrophil Proteinase 3 Acts on Protease-Activated Receptor-2 to Enhance Vascular Endothelial Cell Barrier Function (2013) (34)
- Effect of single amino acid substitutions on the formation of the PlA and Bak alloantigenic epitopes. (1991) (34)
- A Leu262Pro mutation in the integrin β3 subunit results in an αIIb-β3 complex that binds fibrin but not fibrinogen (2000) (34)
- A Ser162→ Leu Mutation within Glycoprotein (GP) IIIa (Integrin β3) Results in an Unstable αIIbβ3 Complex that Retains Partial Function in a Novel Form of Type II Glanzmann Thrombasthenia (1998) (33)
- Nitration of PECAM-1 ITIM tyrosines abrogates phosphorylation and SHP-2 binding. (2002) (33)
- Reconstruction of platelet proteins into phospholipid vesicles. Functional proteoliposomes. (1985) (33)
- Synthesis of analogs of human platelet membrane glycoprotein IIb-IIIa complex by chicken peripheral blood thrombocytes. (1985) (33)
- Blockade of maternal anti‐HPA‐1a–mediated platelet clearance by an HPA‐1a epitope–specific F(ab′)2 in an in vivo mouse model of alloimmune thrombocytopenia (2009) (32)
- Paxillin family members function as Csk-binding proteins that regulate Lyn activity in human and murine platelets. (2007) (32)
- Cell Surface Glycosaminoglycans Do Not Serve as Ligands for PECAM-1 (1998) (31)
- PTH Receptor Signaling in Osteoblasts Regulates Endochondral Vascularization in Maintenance of Postnatal Growth Plate (2015) (30)
- Extraction and identification of human platelet integral membrane proteins using Triton X-114. (1982) (30)
- Monoclonal antibodies bound to subunits of the integrin GPIIb-IIIa are internalized and interfere with filopodia formation and platelet aggregation. (1990) (29)
- Neonatal alloimmune thrombocytopenia due to a new platelet-specific alloantibody. (1993) (28)
- Platelet Activation and Thrombus Formation over IgG Immune Complexes Requires Integrin αIIbβ3 and Lyn Kinase (2015) (27)
- Perspectives Series: Cell Adhesion in Vascular Biology The Biology of PECAM-1 (1996) (27)
- Mechanism of Outside-In &agr;IIb&bgr;3-Mediated Activation of Human Platelets by the Colonizing Bacterium, Streptococcus gordonii* (2010) (26)
- A site involving the "hybrid" and PSI homology domains of GPIIIa (beta 3-integrin subunit) is a common target for antibodies associated with quinine-induced immune thrombocytopenia. (2003) (26)
- The Role of Sialylated Glycans in Human Platelet Endothelial Cell Adhesion Molecule 1 (PECAM-1)-mediated Trans Homophilic Interactions and Endothelial Cell Barrier Function* (2016) (26)
- Disruption of the long-range GPIIIa Cys(5)-Cys(435) disulfide bond results in the production of constitutively active GPIIb-IIIa (alpha(IIb)beta(3)) integrin complexes. (2002) (26)
- Regulation of Endothelial Cell Barrier Function by Antibody-driven Affinity Modulation of Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1)* (2014) (25)
- Mapping early conformational changes in αIIb and β3 during biogenesis reveals a potential mechanism for αIIbβ3 adopting its bent conformation (2007) (25)
- Changes in expression of the cell adhesion molecule PECAM-1 (CD31) during differentiation of human leukemic cell lines. (1994) (24)
- The leukocyte cell adhesion cascade and its role in myocardial ischemia-reperfusion injury (1997) (22)
- Drug-dependent clearance of human platelets in the NOD/scid mouse by antibodies from patients with drug-induced immune thrombocytopenia. (2010) (22)
- A dinucleotide deletion in exon 4 of the PlA2 allelic form of glycoprotein IIIa: implications for the correlation of serologic versus genotypic analysis of human platelet alloantigens. (1996) (20)
- PECAM-1 dampens cytokine levels during LPS-induced endotoxemia by regulating leukocyte trafficking. (2012) (19)
- Reactive oxygen species induce reversible PECAM-1 tyrosine phosphorylation and SHP-2 binding. (2003) (18)
- Disruption of a Long-Range Disulfide Bond Between Residues Cys406 and Cys655 in Glycoprotein IIIa Does Not Affect the Function of Platelet Glycoprotein IIb-IIIa (1997) (18)
- Purification of human platelet membrane glycoproteins IIb and IIIa using high-performance liquid chromatography gel filtration. (1983) (18)
- The role of fibrinogen A alpha chains in ADP-induced platelet aggregation in the presence of fibrinogen molecules containing gamma' chains. (1988) (17)
- PECAM‐1 functions as a negative regulator of laminin‐induced platelet activation (2010) (16)
- The cell-adhesion and signaling molecule PECAM-1 as a molecular mediator of genotoxic chemotherapy resistance (2005) (16)
- Mapping early conformational changes in alphaIIb and beta3 during biogenesis reveals a potential mechanism for alphaIIbbeta3 adopting its bent conformation. (2007) (15)
- Restoration of Responsiveness of Phospholipase Cγ2-Deficient Platelets by Enforced Expression of Phospholipase Cγ1 (2015) (15)
- An alternatively spliced isoform of PECAM-1 is expressed at high levels in human and murine tissues, and suggests a novel role for the C-terminus of PECAM-1 in cytoprotective signaling (2008) (15)
- Phospholipase Cγ2 contributes to stable thrombus formation on VWF (2004) (14)
- The Anti-Inflammatory Actions of Platelet Endothelial Cell Adhesion Molecule-1 Do Not Involve Regulation of Endothelial Cell NF-κB (2010) (14)
- Identification and characterization of functional cation coordination sites in platelet endothelial cell adhesion molecule-1. (1997) (14)
- Adhesive and signaling properties of a naturally occurring allele of glycoprotein IIIa with an amino acid substitution within the ligand binding domain-the Pena/Penb platelet alloantigenic epitopes. (1998) (14)
- Integrin-αIIbβ3-mediated outside-in signalling activates a negative feedback pathway to suppress platelet activation (2016) (14)
- Packaging functionally important plasma proteins into the α‐granules of human‐induced pluripotent stem cell‐derived megakaryocytes (2019) (13)
- Frontline Science: PECAM‐1 (CD31) expression in naïve and memory, but not acutely activated, CD8+ T cells (2018) (13)
- A Leu262Pro mutation in the integrin beta(3) subunit results in an alpha(IIb)-beta(3) complex that binds fibrin but not fibrinogen. (2000) (11)
- The biochemistry of platelet-specific alloantigens. (1986) (11)
- High-resolution mapping of the polyclonal immune response to the human platelet alloantigen HPA-1a (PlA1). (2018) (11)
- Inherited Mutations within the Calcium-Binding Sites of the Integrin αIIb Subunit (Platelet Glycoprotein IIb) (1996) (10)
- Disruption of a long-range disulfide bond between residues Cys406 and Cys655 in glycoprotein IIIa does not affect the function of platelet glycoprotein IIb-IIIa. (1997) (10)
- Identification of Fc (cid:1) RIIa as the ITAM-bearing receptor mediating (cid:2) IIb (cid:3) 3 outside-in integrin signaling in human platelets (2008) (10)
- A Frameshift Mutation at Gly975 in the Transmembrane Domain of GPIIb Prevents GPIIb-IIIa Expression – Analysis of Two Novel Mutations in a Kindred with Type I Glanzmann Thrombasthenia (1998) (10)
- PECAM-1/IgG attenuates peroxynitrite-mediated extremity reperfusion injury. (2001) (10)
- Bioengineered iPSC-derived megakaryocytes for the detection of platelet-specific patient alloantibodies. (2019) (9)
- 31 – SCREENING OF λgt11 LIBRARIES (1990) (9)
- TCR-Mediated Signal Transduction Adhesion Molecule-1 (CD31): Inhibition of A New Role for Platelet-Endothelial Cell (1999) (9)
- HPA-1a/b (PlA1/A2, Zwa/b): the odyssey of an alloantigen system (2007) (8)
- Leukocyte adhesion in pial cerebral venules after PMA stimulation and ischemia/reperfusion in vivo. (1997) (8)
- Hemizygosity for the gene encoding glycoprotein Ibβ is not responsible for macrothrombocytopenia and bleeding in patients with 22q11 deletion syndrome (2019) (7)
- Inherited mutations within the calcium-binding sites of the integrin alpha IIb subunit (platelet glycoprotein IIb). Effects of the amino acid side chain and the amino acid position on cation binding. (1996) (7)
- A Ser162-->Leu mutation within glycoprotein (GP) IIIa (integrin beta3) results in an unstable alphaIIbbeta3 complex that retains partial function in a novel form of type II Glanzmann thrombasthenia. (1998) (6)
- Preclinical evaluation of immunotherapeutic regimens for fetal/neonatal alloimmune thrombocytopenia. (2021) (6)
- Phospholipase Cgamma2 contributes to stable thrombus formation on VWF. (2004) (6)
- Platelet Function Changes during Neonatal Cardiopulmonary Bypass Surgery: Mechanistic Basis and Lack of Correlation with Excessive Bleeding (2019) (6)
- Molecular genetic aspects of human platelet antigen systems. (1991) (6)
- Generation of ‘designer erythroblasts’ lacking one or more blood group systems from CRISPR/Cas9 gene‐edited human‐induced pluripotent stem cells (2021) (5)
- CHAPTER 11 – PECAM-1 (2007) (5)
- CRISPR‐mediated deletion of the PECAM‐1 cytoplasmic domain increases receptor lateral mobility and strengthens endothelial cell junctional integrity (2018) (4)
- T cell receptor and alloimmune thrombocytopenias: a model for autoimmune diseases? (1992) (4)
- Diacylglycerol kinase ζ is a negative regulator of GPVI-mediated platelet activation. (2019) (4)
- Truncation of the Cytoplasmic Domain of (cid:98) 3 in a Variant Form of Glanzmann Thrombasthenia Abrogates Signaling through the Integrin (cid:97) IIb (cid:98) 3 Complex (1997) (4)
- Generation of PECAM‐1 (CD31) conditional knockout mice (2019) (4)
- New role for the GPVI/FcRγ chain complex (2006) (3)
- Conditional CRISPR‐mediated deletion of Lyn kinase enhances differentiation and function of iPSC‐derived megakaryocytes (2021) (2)
- Prophylactic administration of HPA-1a-specific antibodies prevents fetal/neonatal alloimmune thrombocytopenia in mice. (2022) (2)
- Enzymatic amplification of specific cDNA inserts from lambda gt11 libraries. (1988) (2)
- formation in vitro and in vivo Cooperative integrin/ITAM signaling in platelets enhances thrombus (2013) (2)
- The FcR γ Chain Potentiates Outside-In Integrin Signaling. (2006) (2)
- Cardiovascular-Kidney Interactions in Health and Disease Peroxynitrite reduces the endothelium-derived hyperpolarizing factor component of coronary flow-mediated dilation in PECAM-1-knockout mice (2005) (2)
- filamin regulates platelet size by controlling the subcellular localization of α GPIb (2012) (2)
- Overlapping and unique substrate specificities of ST3GAL1 and 2 during hematopoietic and megakaryocytic differentiation (2022) (2)
- GPVI and the not so eager cleaver. (2010) (2)
- Chapter 15 – PECAM-1 (2013) (2)
- Cd31 pecam 1 is an adhesion amplifier on unique t cell subsets (1992) (2)
- FcγRIIa Is Required for Outside-In β3 Integrin Signaling in Human Platelets. (2007) (2)
- High-resolutionmapping of the polyclonal immune response to the human platelet alloantigen HPA-1a (Pl) (2018) (1)
- Effect on ex vivo platelet aggregation and in vivo cyclic flow with Na+/H+ exchange inhibition (2011) (1)
- The Anti-Inflammatory Actions of Platelet Endothelial Cell Adhesion Molecule-1 Do Not Involve Regulation of Endothelial Cell NF-kB (2010) (1)
- Species-Specific Roles for a2,3- and a2,6-Linked Sialic Acid Residues in PECAM-1-Mediated Homophilic Interactions (2015) (1)
- Filamins Regulate Differentiation of Megakaryocytes and Platelets From Cultured Embryonic Stem (ES) Cells. (2010) (1)
- Prevention of Fetal/Neonatal Alloimmune Thrombocytopenia in Mice: Biochemical and Cell Biological Characterization of Isoforms of a Human Monoclonal Antibody (2022) (1)
- Enhancement Of Endothelial Cell Barrier Function By Antibody-Driven Affinity Modulation Of PECAM-1 (2013) (1)
- Construction and expression of an enzymatically active form of PECAM-1 containing the phosphatase domain of the protein tyrosine phosphatase, SHP-2. (2001) (1)
- FcγRIIa Enhances Thrombus Growth in Vitro and in Vivo (2011) (1)
- Atomic Level Dissection of the Platelet Endothelial Cell Adhesion Molecule 1 (PECAM-1) Homophilic Binding Interface: Implications for Endothelial Cell Barrier Function (2021) (1)
- Polymorphism of human platelet membrane glycoprotein iiia and diagnostic and therapeutic applications thereof (1992) (1)
- The HumanPlatelet Alloantigens Bra and Brb Are Associated with a Single Amino Acid Polymorphism on Glycoprotein la ( Integrin Subunit a 2 ) (2013) (1)
- Neutrophil Proteinase 3 (PR3) Enhances Vascular Endothelial Cell Barrier Function (2010) (1)
- High-resolution mapping of the polyclonal immune response to the human platelet alloantigen HPA-1a (Pl A1 ) (2018) (1)
- Variability of PECAM-1 Expression on Blood Cells. (2004) (0)
- Prophylactic Administration of Antibodies Specific for the HPA-1a Epitope Prevents Alloimmunization and Platelet Destruction in a Murine Model of Fetal Neonatal Alloimmune Thrombocytopenia (2021) (0)
- Endothelial Biomedicine: Functions of Platelet-Endothelial Cell Adhesion Molecule-1 in the Vascular Endothelium (2007) (0)
- Integrin αIIbβ3-Mediated Outside-in Signaling: Brake or Amplifier of Platelet Activation? (2014) (0)
- GPIb (cid:1) regulates platelet size by controlling the subcellular localization of filamin (2012) (0)
- Neither Free αIIb nor Free β3 Limits αIIbβ3 Biogenesis, and Pro-αIIbβ3 Adopts a Conformation Akin to Ligand-Bound Mature αIIbβ3. (2005) (0)
- 2008 Russell Ross Memorial Lectureship in Vascular Biology—Activating and Inhibitory Receptors in Blood and Vascular Cells (2008) (0)
- PECAM-1: regulator of endothelial junctional integrity (2014) (0)
- Designer Platelets: Crispr/Cas-Mediated Conversion of Human Platelet Alloantigen Allotypes (2014) (0)
- THROMBOSIS AND HEMOSTASIS Cooperative integrin / ITAM signaling in platelets enhances thrombus formation in vitro and in vivo (2013) (0)
- FcγRIIa and the Integrin β3 Cytoplasmic Domain: Two Prerequisites for Thrombocytopenia and Thrombosis Following Administration of the Fibrinogen Receptor Antagonist, Eptifibatide. (2007) (0)
- The biology of PECAM-1. (1997) (0)
- A Single Amino Acid Substitution Flanking the Fourth Calcium Binding Domain of aIm Prevents Maturation of the aImp, Integrin Complex* (2001) (0)
- Adhesion Molecule-1 Dimorphism of Platelet Endothelial Cell N 536 Influenced by the Endothelial S Neutrophil-Specific Antigen CD177 Is Neutrophil Transmigration Mediated by the (2010) (0)
- Platelet Activation In Sitosterolemia Mice (2010) (0)
- Contribution of outside-in αIIbβ3-mediated activation of human platelets by the colonizing bacterium, Streptococcus gordonii, to the thrombotic complications of infective endocarditis (2010) (0)
- the monoclonal antibody, AP-3 Quantitation of membrane glycoprotein IIIa on intact human platelets using (2011) (0)
- alternative splicing in the glycoprotein IIb gene Glanzmann's thrombasthenia associated with deletion-insertion and (2011) (0)
- PLATELETS AND THROMBOPOIESIS CRISPR / Cas 9-mediated conversion of human platelet alloantigen allotypes (2016) (0)
- induced platelet aggregation without blocking fibrinogen binding Synergistic action of two murine monoclonal antibodies that inhibit ADP (2011) (0)
- An Authentic Murine Model of Fetal/Neonatal Alloimmune Thrombocytopenia (2019) (0)
- Scientific Sessions on Arteriosclerosis, Thrombosis and Vascular Biology (2010) (0)
- Involve Regulation of Endothelial Cell NF-NotEndothelial Cell Adhesion Molecule-1 Do The Anti-Inflammatory Actions of Platelet Newman (2010) (0)
- Glycoprotein IIb-IIIa in Glycoprotein IIIa Does Not Affect the Function of Platelet 655 Cys and 406 Disruption of a Long-Range Disulfide Bond Between Residues Cys (2011) (0)
- An Unexpected Role For αIIbβ3 In Immune Complex Disorders (2013) (0)
- Adhesive and Signaling Properties of a Naturally Occurring Allele of Glycoprotein IIIa With an Amino Acid Substitution Within the Ligand Binding Domain—The Pena/PenbPlatelet Alloantigenic Epitopes (1998) (0)
- Migration of NB1-Positive Neutrophils Proteinase 3 Contributes to Transendothelial (0)
- quinine-induced immune thrombocytopenia 3-integrin subunit) is a common target for antibodies associated with β A site involving the ''hybrid'' and PSI homology domains of GPIIIa ( (2013) (0)
- Crispr/Cas9-Mediated Generation of Mouse Platelets Expressing the Human Platelet Alloantigen, HPA-1a (2015) (0)
- CD4+ T Cells Are Required for Production of Disease-Causing Antibodies in an Alloantigen-Specific Murine Model of Fetal/Neonatal Alloimmune Thrombocytopenia (2022) (0)
- Abstract 25: Platelet Activation by GPVI, GPIb-V-IX and aIIbß3 Requires PLC?2 but Not PLC?1 (2013) (0)
- Blockade of Chemotherapy-Induced Thrombocytopenia by Bax Inhibiting Peptides (BIPs) in Mouse Model. (2007) (0)
- Filamin A Controls Embryonic Stem Cell Differentiation. (2009) (0)
- Block In Vivo Neutrophil Recruitment PECAM-1-Dependent Homophilic Adhesion Molecule-1 (PECAM-1) That Inhibit of Human Platelet Endothelial Cell Adhesion Antibodies Against the First Ig-Like Domain (1999) (0)
- Neutrophil Proteinase (PR3) Regulates Neutrophil Transendothelial Cell Migration. (2010) (0)
- Genetic Removal of Terminal Sialic Acid Residues from the O-Linked Glycans Adjacent to the HPA-9b Polymorphism of Platelet Membrane Glycoprotein IIb Improves the Binding and Detection of HPA-9b Patient Alloantibodies (2021) (0)
- Involvement of the EGF Domain in the Formation of the Human Platelet Alloantigen, HPA-1a (2015) (0)
- Conditional CRISPR-Mediated Deletion of Lyn Kinase Promotes Megakaryocyte Differentiation, Platelet Production and Function (2020) (0)
- Abstract 40: Neutrophil Serine Protease PR3 Promotes Platelet Adhesion and Activation on von Willebrand Factor (vWF) Expressing Endothelial Cells (2013) (0)
- Syndrome in a Novel Form of Bernard-Soulier α Circulating Soluble Glycoprotein Ib A Dinucleotide Deletion Results in Defective Membrane Anchoring and (2013) (0)
- PECAM-1 Is a Negative Regulator of Platelet Activation by Laminin. (2007) (0)
- Human Platelets Express Functional Pannexin-1 (2011) (0)
- Crystal structure of PECAM-1 D1D2 domain (2016) (0)
- Disaggregation Signals Initiated by Ligand Binding and Platelet Aggregation (2011) (0)
- Atomic-Level Dissection of the Polyclonal Immune Response to the Human Platelet Alloantigen, HPA-1a (PlA1) (2018) (0)
- FcγRIIa Rescues Normally-Poor αIIbβ3-Mediated Outside-in Signaling in Mouse Platelets. (2009) (0)
- in the presence of fibrinogen molecules containing gamma' chains The role of fibrinogen A alpha chains in ADP-induced platelet aggregation (2011) (0)
- Prevention of Fetal/Neonatal Alloimmune Thrombocytopenia in a Preclinical Model By Monoclonal Anti-HPA-1a Antibody Prophylaxis: Structural and Functional Properties of Antibody Variant Isoforms (2021) (0)
- ATVB In Focus Platelet Activation and the Formation of the Platelet Plug (2010) (0)
- Disruption of the long-range GPIIIa Cys 5 -Cys 435 disulfide bond results in the production of constitutively active GPIIb-IIIa ( (cid:1) IIb (cid:2) 3 ) integrin complexes (2002) (0)
- Paxillin Becomes Tyrosine-Phosphorylated and Binds Csk in a GpIIb-IIIa-Dependent Manner Following GPVI-Induced Activation of Murine Platelets. (2004) (0)
- Quantitative Measurement of VWF Binding to the Platelet Integrin αIIbβ3 - Abnormalities Identified in Individuals with VWD (2015) (0)
- Generation of iPSC-Derived Human Megakaryocytes for Flow Cytometric Detection of Platelet-Specific Alloantibodies (2018) (0)
- Reactive oxygen species induce reversible PECAM-1 tyrosine phosphorylation and SHP-2 binding : Vascular signaling by free radicals (2003) (0)
- Patent Number : 45 ) Date of Patent : 5 , 436 , 163 Jul . 25 , 1995 (2017) (0)
- The Neutrophil Specific CD177 Is a Novel Counter-Receptor for Endothelial PECAM-1. (2006) (0)
- Drug Dependent Immune Destruction of Human Platelets in the NOD/SCID Mouse. (2008) (0)
- PECAM-1 Inhibits Signaling Pathways That Amplify Platelet Aggregation. (2006) (0)
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What Schools Are Affiliated With Peter. J. Newman?
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