Peter Jan Sterk

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Peter Jan Sterk is affiliated with the following schools: University of Amsterdam, Leiden University

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Peter Jan Sterk

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#331

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#431

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Peter Jan Sterk's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma (2013) (2784)
Guidelines for methacholine and exercise challenge testing-1999. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors, July 1999. (2000) (2420)
Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsìveness, and the late asthmatic response (2000) (1869)
An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials and clinical practice. (2009) (1585)
Airway responsiveness. Standardized challenge testing with pharmacological, physical and sensitizing stimuli in adults. Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal. Official Statement of the European Respiratory Society. (1993) (1138)
Clinical control and histopathologic outcome of asthma when using airway hyperresponsiveness as an additional guide to long-term treatment. The AMPUL Study Group. (1999) (912)
Nitric oxide in health and disease of the respiratory system. (2004) (837)
Long-term effects of a long-acting beta 2-adrenoceptor agonist, salmeterol, on airway hyperresponsiveness in patients with mild asthma. (1992) (452)
An electronic nose in the discrimination of patients with asthma and controls. (2007) (428)
Risk factors of frequent exacerbations in difficult-to-treat asthma (2005) (428)
A new perspective on concepts of asthma severity and control (2008) (420)
Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort (2015) (400)
A European Respiratory Society technical standard: exhaled biomarkers in lung disease (2017) (383)
Airway smooth muscle dynamics: a common pathway of airway obstruction in asthma (2007) (383)
External validation of blood eosinophils, FENO and serum periostin as surrogates for sputum eosinophils in asthma (2014) (382)
Difficult/therapy-resistant asthma: the need for an integrated approach to define clinical phenotypes, evaluate risk factors, understand pathophysiology and find novel therapies. ERS Task Force on Difficult/Therapy-Resistant Asthma. European Respiratory Society. (1999) (378)
Factors associated with persistent airflow limitation in severe asthma. (2001) (354)
Diagnosis and definition of severe refractory asthma: an international consensus statement from the Innovative Medicine Initiative (IMI) (2010) (340)
Standardised methodology of sputum induction and processing (2002) (333)
Volatile Metabolites of Pathogens: A Systematic Review (2013) (328)
Severe asthma in adults: what are the important questions? (2007) (293)
Sputum induction (2002) (289)
Reduction in sputum neutrophil and eosinophil numbers by the PDE4 inhibitor roflumilast in patients with COPD (2007) (287)
Chronic sinusitis in severe asthma is related to sputum eosinophilia. (2002) (286)
Effect of inhaled steroids on airway hyperresponsiveness, sputum eosinophils, and exhaled nitric oxide levels in patients with asthma (1999) (282)
Relationship between the inflammatory infiltrate in bronchial biopsy specimens and clinical severity of asthma in patients treated with inhaled steroids. (1996) (247)
T-helper cell type 2 (Th2) and non-Th2 molecular phenotypes of asthma using sputum transcriptomics in U-BIOPRED (2017) (246)
Application of ’omics technologies to biomarker discovery in inflammatory lung diseases (2013) (236)
"Refractory" eosinophilic airway inflammation in severe asthma: effect of parenteral corticosteroids. (2004) (233)
Recurrent exacerbations in severe asthma are associated with enhanced airway closure during stable episodes. (2000) (233)
Systems medicine and integrated care to combat chronic noncommunicable diseases (2011) (230)
Murine models of asthma (2003) (213)
Repeatability of cellular and soluble markers of inflammation in induced sputum from patients with asthma. (1996) (212)
ERS technical standard on bronchial challenge testing: general considerations and performance of methacholine challenge tests (2017) (210)
Experimental rhinovirus 16 infection. Effects on cell differentials and soluble markers in sputum in asthmatic subjects. (1997) (210)
U‐BIOPRED clinical adult asthma clusters linked to a subset of sputum omics (2017) (210)
Diagnostic accuracy of minimally invasive markers for detection of airway eosinophilia in asthma: a systematic review and meta-analysis. (2015) (210)
Effect of experimental rhinovirus 16 colds on airway hyperresponsiveness to histamine and interleukin‐8 in nasal lavage in asthmatic subjects in vivo (1997) (210)
Effect of fluticasone with and without salmeterol on pulmonary outcomes in chronic obstructive pulmonary disease: a randomized trial. (2009) (203)
Bronchial hyperresponsiveness: the need for a distinction between hypersensitivity and excessive airway narrowing. (1989) (199)
Asthma therapy and airway remodeling. (2007) (196)
The burden of severe asthma in childhood and adolescence: results from the paediatric U-BIOPRED cohorts (2015) (178)
Severe adult-onset asthma: A distinct phenotype. (2013) (178)
Defensins: key players or bystanders in infection, injury, and repair in the lung? (1999) (177)
Internet-Based Self-management Plus Education Compared With Usual Care in Asthma (2009) (177)
Chronic obstructive pulmonary disease: role of bronchiolar mast cells and macrophages. (1997) (175)
Comparison of inflammatory cell counts in asthma: induced sputum vs bronchoalveolar lavage and bronchial biopsies (1997) (173)
Rhinovirus inhalation causes long-lasting excessive airway narrowing in response to methacholine in asthmatic subjects in vivo. (1995) (170)
Standardized challenge testing with pharmacological, physical and sensitizing stimuli in adults (1993) (170)
Modules, networks and systems medicine for understanding disease and aiding diagnosis (2014) (170)
Relation between duration of smoking cessation and bronchial inflammation in COPD (2005) (169)
Safety of sputum induction (2002) (167)
Relationship between exhaled nitric oxide and airway hyperresponsiveness following experimental rhinovirus infection in asthmatic subjects. (1998) (165)
The long-term effects of nedocromil sodium and beclomethasone dipropionate on bronchial responsiveness to methacholine in nonatopic asthmatic subjects. (1990) (164)
Persistent airflow limitation in adult-onset nonatopic asthma is associated with serologic evidence of Chlamydia pneumoniae infection. (2001) (162)
Oral leukotriene inhibitor (MK-886) blocks allergen-induced airway responses. (1993) (162)
Enhanced bronchial expression of vascular endothelial growth factor and receptors (Flk-1 and Flt-1) in patients with chronic obstructive pulmonary disease (2005) (161)
The effect of inhaled leukotriene D4 and methacholine on sputum cell differentials in asthma. (1997) (160)
Breathomics in lung disease. (2015) (157)
Integrated care pathways for airway diseases (AIRWAYS-ICPs) (2014) (155)
Bronchial CD8 cell infiltrate and lung function decline in asthma. (2005) (154)
An integrative systems biology approach to understanding pulmonary diseases. (2010) (154)
The effect of MK-0591, a novel 5-lipoxygenase activating protein inhibitor, on leukotriene biosynthesis and allergen-induced airway responses in asthmatic subjects in vivo. (1995) (153)
Exhaled air molecular profiling in relation to inflammatory subtype and activity in COPD (2011) (149)
A Transcriptome‐driven Analysis of Epithelial Brushings and Bronchial Biopsies to Define Asthma Phenotypes in U‐BIOPRED (2017) (149)
Benefits of high altitude allergen avoidance in atopic adolescents with moderate to severe asthma, over and above treatment with high dose inhaled steroids (2001) (143)
Enhanced bronchial expression of extracellular matrix proteins in chronic obstructive pulmonary disease. (2006) (142)
Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study (2019) (141)
Three phenotypes of adult‐onset asthma (2013) (140)
Alveolar nitric oxide versus measures of peripheral airway dysfunction in severe asthma (2006) (137)
A dynamic bronchial airway gene expression signature of chronic obstructive pulmonary disease and lung function impairment. (2013) (136)
Long-term effects of chemotherapy in patients with testicular cancer. (1992) (135)
Effect of inhaled heparin on allergen-induced early and late asthmatic responses in patients with atopic asthma. (1996) (135)
A Severe Asthma Disease Signature from Gene Expression Profiling of Peripheral Blood from U‐BIOPRED Cohorts (2017) (135)
Sputum transcriptomics reveal upregulation of IL‐1 receptor family members in patients with severe asthma (2017) (135)
Precision medicine in airway diseases: moving to clinical practice (2017) (134)
Dissociation of lung function and airway inflammation in chronic obstructive pulmonary disease. (2004) (133)
Exhaled breath analysis by electronic nose in airways disease. Established issues and key questions (2013) (131)
Exhaled Molecular Fingerprinting in Diagnosis and Monitoring: Validating Volatile Promises. (2015) (129)
Bronchial inflammation and airway responses to deep inspiration in asthma and chronic obstructive pulmonary disease. (2007) (128)
Lung function and sputum characteristics of patients with severe asthma during an induced exacerbation by double-blind steroid withdrawal. (1999) (128)
Impaired perception of dyspnea in patients with severe asthma. Relation to sputum eosinophils. (1998) (128)
Exhaled nitric oxide (NO) is reduced shortly after bronchoconstriction to direct and indirect stimuli in asthma. (1998) (128)
Bronchoconstriction induced by citric acid inhalation in guinea pigs: role of tachykinins, bradykinin, and nitric oxide. (1999) (125)
Long-Term Effects of a Long-acting ??2-Adrenoceptor Agonist, Salmeterol, on Airways Hyperresponsiveness in Patients with Mild Asthma (1993) (125)
Dose‐responses over time to inhaled fluticasone propionate treatment of exercise‐ and methacholine‐induced bronchoconstriction in children with asthma (2000) (125)
ARIA 2016: Care pathways implementing emerging technologies for predictive medicine in rhinitis and asthma across the life cycle (2016) (124)
The effect of inhaled corticosteroids on the maximal degree of airway narrowing to methacholine in asthmatic subjects. (1991) (121)
Exhaled nitric oxide predicts lung function decline in difficult-to-treat asthma (2008) (120)
Rhinovirus-induced airway inflammation in asthma: effect of treatment with inhaled corticosteroids before and during experimental infection. (2001) (120)
Epithelial IL‐6 trans‐signaling defines a new asthma phenotype with increased airway inflammation (2019) (119)
Consistency of sputum eosinophilia in difficult-to-treat asthma: a 5-year follow-up study. (2009) (118)
Asthma severity and susceptibility to air pollution. (1998) (117)
An electronic nose distinguishes exhaled breath of patients with Malignant Pleural Mesothelioma from controls. (2012) (117)
Exhaled breath metabolomics as a noninvasive diagnostic tool for acute respiratory distress syndrome (2014) (115)
Extracellular matrix composition in COPD (2012) (114)
Assessing the effect of deep inhalation on airway calibre: a novel approach to lung function in bronchial asthma and COPD. (1998) (112)
Experimental rhinovirus 16 infection causes variable airway obstruction in subjects with atopic asthma. (1999) (110)
The dynamics of the pulmonary microbiome during mechanical ventilation in the intensive care unit and the association with occurrence of pneumonia (2017) (108)
Limited bronchoconstriction to methacholine using partial flow-volume curves in nonasthmatic subjects. (1985) (106)
Small airways function and molecular markers in exhaled air in mild asthma (2005) (106)
Internet-based self-management offers an opportunity to achieve better asthma control in adolescents. (2007) (102)
The effect of an inhaled neutral endopeptidase inhibitor, thiorphan, on airway responses to neurokinin A in normal humans in vivo. (1992) (100)
Validated and longitudinally stable asthma phenotypes based on cluster analysis of the ADEPT study (2016) (100)
Eotaxin-2 and eotaxin-3 expression is associated with persistent eosinophilic bronchial inflammation in patients with asthma after allergen challenge. (2005) (99)
Maximal airway narrowing to inhaled leukotriene D4 in normal subjects. Comparison and interaction with methacholine. (1987) (99)
Publication Bias in Laboratory Animal Research: A Survey on Magnitude, Drivers, Consequences and Potential Solutions (2012) (98)
Integration of electronic nose technology with spirometry: validation of a new approach for exhaled breath analysis (2014) (97)
Inhaled allergen bronchoprovocation tests. (2013) (97)
Is diet partly responsible for differences in COVID-19 death rates between and within countries? (2020) (96)
“T2-high” in severe asthma related to blood eosinophil, exhaled nitric oxide and serum periostin (2019) (95)
Tobacco use in relation to COPD and asthma (2007) (95)
Risk of deep vein thrombosis and pulmonary embolism in asthma (2012) (95)
Severe Chronic Allergic (and Related) Diseases: A Uniform Approach – A MeDALL – GA2LEN – ARIA Position Paper (2012) (93)
Clinical and inflammatory phenotyping by breathomics in chronic airway diseases irrespective of the diagnostic label (2018) (92)
Allergen-induced impairment of bronchoprotective nitric oxide synthesis in asthma. (2001) (91)
The protective effect of a beta 2 agonist against excessive airway narrowing in response to bronchoconstrictor stimuli in asthma and chronic obstructive lung disease. (1991) (90)
Symbols, abbreviations and units. Working Party Standardization of Lung Function Tests, European Community for Steel and Coal. (1993) (89)
Physical properties of aerosols produced by several jet- and ultrasonic nebulizers. (1984) (87)
Validity of peak expiratory flow measurement in assessing reversibility of airflow obstruction. (1992) (87)
Chronic bronchitis sub-phenotype within COPD: inflammation in sputum and biopsies (2008) (86)
Smoking status and anti-inflammatory macrophages in bronchoalveolar lavage and induced sputum in COPD (2011) (85)
Neutral endopeptidase activity and airway hyperresponsiveness to neurokinin A in asthmatic subjects in vivo. (1993) (84)
Effects of inhaled substance P on airway responsiveness to methacholine in asthmatic subjects in vivo. (1994) (84)
Asymptomatic worsening of airway inflammation during low-dose allergen exposure in asthma: protection by inhaled steroids. (2002) (82)
Understanding the complexity of IgE-related phenotypes from childhood to young adulthood: a Mechanisms of the Development of Allergy (MeDALL) seminar. (2012) (82)
Transcriptome sequencing (RNA-Seq) of human endobronchial biopsies: asthma versus controls (2013) (80)
Clinical applications of assessment of airway inflammation using induced sputum (2002) (80)
Association of anxiety with perception of histamine induced bronchoconstriction in patients with asthma. (1997) (80)
Breathomics in the setting of asthma and chronic obstructive pulmonary disease. (2016) (80)
Inhaled Steroids Modulate Extracellular Matrix Composition in Bronchial Biopsies of COPD Patients: A Randomized, Controlled Trial (2013) (80)
Enhanced expression of fibroblast growth factors and receptor FGFR-1 during vascular remodeling in chronic obstructive pulmonary disease. (2002) (79)
ERS technical standard on bronchial challenge testing: pathophysiology and methodology of indirect airway challenge testing (2018) (79)
Virus-induced airway hyperresponsiveness in man. (1993) (77)
Electronic Nose Technology for Detection of Invasive Pulmonary Aspergillosis in Prolonged Chemotherapy-Induced Neutropenia: a Proof-of-Principle Study (2013) (77)
Airway gene expression in COPD is dynamic with inhaled corticosteroid treatment and reflects biological pathways associated with disease activity (2013) (76)
Induced sputum in adolescents with severe stable asthma. Safety and the relationship of cell counts and eosinophil cationic protein to clinical severity. (1999) (74)
Symbols, abbreviations and units (1993) (74)
Personalized respiratory medicine: exploring the horizon, addressing the issues. Summary of a BRN-AJRCCM workshop held in Barcelona on June 12, 2014. (2015) (74)
Breathomics from exhaled volatile organic compounds in pediatric asthma (2017) (74)
Eosinophils capture viruses, a capacity that is defective in asthma (2019) (73)
Chronic obstructive pulmonary disease is associated with enhanced bronchial expression of FGF‐1, FGF‐2, and FGFR‐1 (2005) (72)
Expression of smooth muscle and extracellular matrix proteins in relation to airway function in asthma. (2008) (71)
Exhaled breath profiles in the monitoring of loss of control and clinical recovery in asthma (2017) (71)
Assessment of microvascular leakage via sputum induction: the role of substance P and neurokinin A in patients with asthma. (2002) (71)
Symptom- and fraction of exhaled nitric oxide-driven strategies for asthma control: A cluster-randomized trial in primary care. (2015) (71)
Differential distribution of inflammatory cells in large and small airways in smokers (2006) (71)
Effects of flutter and PEP mask physiotherapy on symptoms and lung function in children with cystic fibrosis. (1998) (70)
Long-term asthma treatment guided by airway hyperresponsiveness in children: a randomised controlled trial (2007) (68)
Are rhinovirus-induced airway responses in asthma aggravated by chronic allergen exposure? (2003) (67)
Weekly self-monitoring and treatment adjustment benefit patients with partly controlled and uncontrolled asthma: an analysis of the SMASHING study (2010) (67)
Effect of transportation and storage using sorbent tubes of exhaled breath samples on diagnostic accuracy of electronic nose analysis (2012) (66)
Identifying patients at risk for severe exacerbations of asthma: development and external validation of a multivariable prediction model (2016) (66)
Glucocorticoid-induced changes in gene expression of airway smooth muscle in patients with asthma. (2013) (65)
Biomarkers in asthma and allergic rhinitis. (2010) (65)
Identification and prospective stability of electronic nose (eNose)–derived inflammatory phenotypes in patients with severe asthma (2019) (64)
Systems medicine approaches for the definition of complex phenotypes in chronic diseases and ageing. From concept to implementation and policies. (2014) (64)
Sputum induction in severe asthma by a standardized protocol: predictors of excessive bronchoconstriction. (2001) (64)
Effect of an NK1/NK2 receptor antagonist on airway responses and inflammation to allergen in asthma. (2007) (63)
Expression of the anaphylatoxin receptors C3aR and C5aR is increased in fatal asthma. (2005) (63)
The excretion of leukotriene E4 into urine following inhalation of leukotriene D4 by human individuals. (1987) (63)
IL-17-high asthma with features of a psoriasis immunophenotype. (2019) (62)
Clinical and inflammatory determinants of bronchial hyperresponsiveness in COPD (2012) (62)
Comparison of exhaled breath condensate pH using two commercially available devices in healthy controls, asthma and COPD patients (2009) (60)
Comparative effectiveness of long term drug treatment strategies to prevent asthma exacerbations: network meta-analysis (2014) (60)
Let's not forget: the GOLD criteria for COPD are based on post-bronchodilator FEV1 (2004) (60)
Small airways dysfunction and neutrophilic inflammation in bronchial biopsies and BAL in COPD. (2007) (60)
Combined sputum hypermethylation and eNose analysis for lung cancer diagnosis (2014) (59)
The effect of an inhaled leukotriene antagonist, L-648,051, on early and late asthmatic reactions and subsequent increase in airway responsiveness in man. (1990) (59)
Internet-based tapering of oral corticosteroids in severe asthma: a pragmatic randomised controlled trial (2011) (58)
Ozone-induced inflammation assessed in sputum and bronchial lavage fluid from asthmatics: a new noninvasive tool in epidemiologic studies on air pollution and asthma. (1999) (58)
Comparison of classification methods in breath analysis by electronic nose (2015) (57)
Rhinovirus infections: induction and modulation of airways inflammation in asthma (1999) (57)
Effects of experimental rhinovirus 16 infection on airway hyperresponsiveness to bradykinin in asthmatic subjects in vivo. (1997) (56)
Abnormal lung sounds in patients with asthma during episodes with normal lung function. (1994) (56)
Anti‐IL‐5 in Mild Asthma Alters Rhinovirus‐induced Macrophage, B‐Cell, and Neutrophil Responses (MATERIAL). A Placebo‐controlled, Double‐Blind Study (2019) (55)
Cost-Effectiveness of Internet-Based Self-Management Compared with Usual Care in Asthma (2011) (55)
Cardiovascular side effects of inhaled salbutamol in hypoxic asthmatic patients (2001) (55)
Maximal airway narrowing in humans in vivo. Histamine compared with methacholine. (1986) (54)
Exhaled molecular profiles in the assessment of cystic fibrosis and primary ciliary dyskinesia. (2013) (54)
Anxiety, depression and personality traits in severe, prednisone-dependent asthma. (2014) (54)
Sputum proteomics and airway cell transcripts of current and ex-smokers with severe asthma in U-BIOPRED: an exploratory analysis (2018) (52)
The use of induced sputum in clinical trials (2002) (52)
Building bridges for innovation in ageing: Synergies between action groups of the EIP on AHA (2016) (52)
Doxycycline for outpatient-treated acute exacerbations of COPD: a randomised double-blind placebo-controlled trial. (2017) (51)
Exhaled breath analysis with electronic nose technology for detection of acute liver failure in rats. (2014) (51)
Does a single dose of the phosphodiesterase 4 inhibitor, cilomilast (15 mg), induce bronchodilation in patients with chronic obstructive pulmonary disease? (2003) (51)
Safety of long-acting β-agonists: urgent need to clear the air remains (2009) (51)
Fluctuations and determinism of respiratory impedance in asthma and chronic obstructive pulmonary disease. (2010) (50)
The “Shrinking lung syndrome” in SLE, treatment with theophylline (1993) (50)
The shape of the dose-response curve to inhaled bronchoconstrictor agents in asthma and in chronic obstructive pulmonary disease. (1991) (49)
Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5) (2016) (49)
Lung sound intensity in patients with emphysema and in normal subjects at standardised airflows. (1992) (49)
Fully automated assessment of inflammatory cell counts and cytokine expression in bronchial tissue. (2003) (49)
Is there a specific relationship between asthma and panic disorder? (1996) (49)
Enhanced expression of neutral endopeptidase (NEP) in airway epithelium in biopsies from steroid- versus nonsteroid-treated patients with atopic asthma. (1997) (49)
The effect of inhaled budesonide on the maximal degree of airway narrowing to leukotriene D4 and methacholine in normal subjects in vivo. (1989) (48)
Breath analysis by gas chromatography-mass spectrometry and electronic nose to screen for pleural mesothelioma: a cross-sectional case-control study (2017) (47)
Long-term multicentre trial in chronic nonspecific lung disease: methodology and baseline assessment in adult patients. Dutch CNSLD Study Group. (1992) (47)
Standardised methodology of sputum induction and processing. Future directions. (2002) (46)
Electronic Nose Breathprints Are Independent of Acute Changes in Airway Caliber in Asthma (2010) (46)
Multi-scale computational models of the airways to unravel the pathophysiological mechanisms in asthma and chronic obstructive pulmonary disease (AirPROM) (2013) (46)
Exhaled breath profiling for diagnosing acute respiratory distress syndrome (2014) (45)
An electronic nose discriminates exhaled breath of patients with untreated pulmonary sarcoidosis from controls. (2013) (45)
Rhinovirus infection in nonasthmatic subjects: effects on intrapulmonary airways (2002) (44)
Stratification of asthma phenotypes by airway proteomic signatures. (2019) (44)
Changes in microbiota during experimental human Rhinovirus infection (2015) (43)
Systemic tryptophan and kynurenine catabolite levels relate to severity of rhinovirus-induced asthma exacerbation: a prospective study with a parallel-group design (2013) (43)
Role of nitric oxide in the airway response to exercise in healthy and asthmatic subjects. (2001) (43)
The message from the World Asthma Meeting. The Working Groups of the World Asthma Meeting, held in Barcelona, Spain, December 9-13, 1998. (1999) (43)
Extracellular matrix in airway smooth muscle is associated with dynamics of airway function in asthma (2012) (43)
Limited maximal airway narrowing in nonasthmatic subjects. Role of neural control and prostaglandin release. (1985) (42)
Altered exhaled biomarker profiles in children during and after rhinovirus-induced wheeze (2014) (42)
Exacerbations in Adults with Asthma: A Systematic Review and External Validation of Prediction Models. (2018) (42)
Proliferation and inflammation in bronchial epithelium after allergen in atopic asthmatics (2003) (42)
Effect of ozone exposure on maximal airway narrowing in non-asthmatic and asthmatic subjects. (1995) (42)
DNA hypermethylation analysis in sputum for the diagnosis of lung cancer: training validation set approach (2015) (40)
Effect of oral L-arginine on airway hyperresponsiveness to histamine in asthma. (1999) (40)
Importance of total serum IgE for improvement in airways hyperresponsiveness with inhaled corticosteroids in asthma and chronic obstructive pulmonary disease. The Dutch CNSLD Study Group. (1995) (40)
The severity of breathlessness during challenges with inhaled methacholine and hypertonic saline in atopic asthmatic subjects. The relationship with deep breath-induced bronchodilation. (1995) (40)
Severe asthma exists despite suppressed tissue inflammation: findings of the U-BIOPRED study (2016) (40)
Evidence for systemic rather than pulmonary effects of interleukin-5 administration in asthma (2001) (40)
Repeatability of measures of inflammatory cell number in bronchial biopsies in atopic asthma. (1997) (39)
Inhalation Challenge Tests and Airway Responsiveness in Man (1985) (39)
Antileukoprotease-containing bronchiolar cells. Relationship with morphologic disease of small airways and parenchyma. (1989) (39)
Systems Biology and Clinical Practice in Respiratory Medicine. The Twain Shall Meet. (2016) (39)
A simple breath sampling method in intubated and mechanically ventilated critically ill patients (2014) (39)
Sputum microbiome profiles identify severe asthma phenotypes of relative stability at 12-18 months. (2020) (38)
Detection of Airway Colonization by Aspergillus fumigatus by Use of Electronic Nose Technology in Patients with Cystic Fibrosis (2015) (38)
A systems medicine clinical platform for understanding and managing non- communicable diseases. (2014) (36)
Urinary Leukotriene E4 and Prostaglandin D2 Metabolites Increase in Adult and Childhood Severe Asthma Characterized by Type 2 Inflammation. A Clinical Observational Study (2020) (36)
Toll‐like receptor 3 blockade in rhinovirus‐induced experimental asthma exacerbations: A randomized controlled study (2017) (36)
Alterations in exhaled breath metabolite-mixtures in two rat models of lipopolysaccharide-induced lung injury. (2013) (35)
In vivo imaging of the airway wall in asthma: fibered confocal fluorescence microscopy in relation to histology and lung function (2011) (35)
Transcriptomic gene signatures associated with persistent airflow limitation in patients with severe asthma (2017) (35)
Comparison of maximal bronchoconstriction in vivo and airway smooth muscle responses in vitro in nonasthmatic humans. (1988) (34)
Relapse in FEV1 Decline After Steroid Withdrawal in COPD. (2015) (34)
Lung sounds during allergen-induced asthmatic responses in patients with asthma. (1996) (34)
Exhaled nitric oxide in COPD: glancing through a smoke screen (1999) (34)
Lung function decline in asthma patients with elevated bronchial CD8, CD4 and CD3 cells (2016) (34)
Protective effect of inhaled budesonide against unlimited airway narrowing to methacholine in atopic patients with asthma. (1997) (34)
The Impact of Allergic Rhinitis and Asthma on Human Nasal and Bronchial Epithelial Gene Expression (2013) (33)
The effect of methacholine-induced acute airway narrowing on lung sounds in normal and asthmatic subjects. (1995) (33)
The volatile metabolic fingerprint of ventilator-associated pneumonia (2014) (33)
Emerging understanding of the mechanism of action of Bronchial Thermoplasty in asthma (2018) (33)
Changes of nebulizer output over the years. (1992) (32)
Detection of exacerbations in asthma based on electronic diary data: results from the 1-year prospective BIOAIR study (2013) (32)
Efficacy of the novel phosphodiesterase-4 inhibitor BAY 19-8004 on lung function and airway inflammation in asthma and chronic obstructive pulmonary disease (COPD). (2003) (32)
Longitudinally Stable, Clinically Defined Clusters of Patients with Asthma Independently Identified in the ADEPT and U-BIOPRED Asthma Studies. (2016) (32)
Airway inflammation in COPD after long-term withdrawal of inhaled corticosteroids (2016) (32)
Relation between small airways disease and parenchymal destruction in surgical lung specimens. (1990) (32)
Contribution of airway eosinophils in airway wall remodeling in asthma: Role of MMP‐10 and MET (2019) (32)
The effect of a single inhaled dose of a VLA‐4 antagonist on allergen‐induced airway responses and airway inflammation in patients with asthma (2006) (31)
Subphenotypes of Mild-to-Moderate COPD by Factor and Cluster Analysis of Pulmonary Function, CT Imaging and Breathomics in a Population-Based Survey (2013) (31)
Pressure-volume analysis of the lung with an exponential and linear-exponential model in asthma and COPD. Dutch CNSLD Study Group. (1995) (31)
Oxygen‐assisted exercise training in adult cystic fibrosis patients with pulmonary limitation to exercise (1991) (31)
Effect of bradykinin on allergen induced increase in exhaled nitric oxide in asthma (2003) (31)
Treatable traits in the European U‐BIOPRED adult asthma cohorts (2018) (30)
Smelling the Diagnosis: The Electronic Nose as Diagnostic Tool in Inflammatory Arthritis. A Case-Reference Study (2016) (30)
Sample size estimation in studies monitoring exercise-induced bronchoconstriction in asthmatic children. (1997) (30)
Prediction of response to anti-PD-1 therapy in patients with non-small-cell lung cancer by electronic nose analysis of exhaled breath. (2019) (30)
Noninvasive methods to measure airway inflammation: future considerations. (2000) (29)
Improvement in bronchodilation following deep inspiration after a course of high-dose oral prednisone in asthma. (2006) (29)
Bradykinin-induced asthmatic fibroblast/myofibroblast activities via bradykinin B2 receptor and different MAPK pathways. (2013) (29)
Transcriptional machinery in asthma: closing the gap with clinical phenotypes. (2002) (28)
Airway remodelling: the future (2007) (28)
Long‐term future risk of severe exacerbations: Distinct 5‐year trajectories of problematic asthma (2017) (28)
Complex systems in pulmonary medicine: a systems biology approach to lung disease. (2011) (28)
Inhaled hyaluronic acid against exercise-induced bronchoconstriction in asthma. (2006) (28)
Prolonged recovery from exercise‐induced asthma with increasing age in childhood (1995) (28)
Susceptibility to Chronic Mucus Hypersecretion, a Genome Wide Association Study (2011) (28)
Airway inflammation contributes to health status in COPD: a cross-sectional study (2006) (27)
Measurement of exhaled nitric oxide as a potential screening tool for pulmonary tuberculosis. (2011) (27)
The value of the forced expiration technique with and without postural drainage in adults with cystic fibrosis. (1986) (27)
Glucose prediction by analysis of exhaled metabolites – a systematic review (2014) (27)
The determinants of airway hyperresponsiveness to hypertonic saline in atopic asthma in vivo. Relationship with sub‐populations of peripheral blood leucocytes (1993) (26)
Long‐term effects of exercise training and hyperalimentation in adult cystic fibrosis patients with severe pulmonary dysfunction (1992) (25)
Comparison of maximal airway narrowing to methacholine between children and adults. (1991) (25)
CD8(+) T cells characterize early smoking-related airway pathology in patients with asthma. (2013) (25)
Clinical, virological and epidemiological characteristics of rhinovirus infections in early childhood: A comparison between non-hospitalised and hospitalised children (2015) (24)
Effect of long-term corticosteroid treatment on microRNA and gene-expression profiles in COPD (2019) (24)
Assessment of pulmonary oxygen toxicity: Relevance to professional diving; a review (2013) (24)
Evaluation of coagulation activation after Rhinovirus infection in patients with asthma and healthy control subjects: an observational study (2014) (24)
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The hyperventilation provocation test in panic disorder. (1992) (23)
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The physical properties of a jet-nebulizer and their relevance for the histamine provocation test. (1983) (22)
Rhinovirus‐16 induced temporal interferon responses in nasal epithelium links with viral clearance and symptoms (2019) (22)
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Do eosinophils contribute to oxidative stress in mild asthma? (2019) (21)
The long‐term effect of nedocromil sodium on the maximal degree of airway narrowing to methacholine in atopic asthmatic subjects (1992) (20)
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Asthma phenotyping: TH2-high, TH2-low, and beyond. (2014) (18)
Biomarkers and asthma management: analysis and potential applications (2018) (18)
Methodological considerations for large-scale breath analysis studies: lessons from the U-BIOPRED severe asthma project (2018) (18)
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The combined effects of histamine and methacholine on the maximal degree of airway narrowing in normal humans in vivo. (1988) (17)
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Three Major Efforts to Phenotype Asthma: Severe Asthma Research Program, Asthma Disease Endotyping for Personalized Therapeutics, and Unbiased Biomarkers for the Prediction of Respiratory Disease Outcome. (2019) (16)
Steroid Resistance in COPD? Overlap and Differential Anti-Inflammatory Effects in Smokers and Ex-Smokers (2014) (16)
Enhanced oxidative stress in smoking and ex-smoking severe asthma in the U-BIOPRED cohort (2018) (16)
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Perception of Bronchoconstriction: A Complementary Disease Marker in Children with Asthma (2013) (15)
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Lipopolysaccharide amplifies eosinophilic inflammation after segmental challenge with house dust mite in asthmatics (2015) (14)
Levels of cytokines in broncho-alveolar lavage fluid, but not in plasma, are associated with levels of markers of lipid peroxidation in breath of ventilated ICU patients (2015) (14)
Electronic nose identifies bronchoalveolar lavage fluid eosinophils in asthma. (2015) (14)
Exacerbation-Prone Asthma: A Separate Bioclinical Phenotype? (2017) (14)
Type 2‐low asthma phenotypes by integration of sputum transcriptomics and serum proteomics (2020) (14)
Large-Scale Label-Free Quantitative Mapping of the Sputum Proteome. (2018) (13)
eNose technology can detect and classify human pathogenic molds in vitro: a proof-of-concept study of Aspergillus fumigatus and Rhizopus oryzae (2016) (13)
Measuring metabolomics in acute lung injury: choosing the correct compartment? (2012) (13)
Bronchial hyperresponsiveness: definition and terminology (1996) (13)
Ventilation inhomogeneity in α1-antitrypsin-deficient emphysema (2006) (13)
Ruling out SARS-CoV-2 infection using exhaled breath analysis by electronic nose in a public health setting (2021) (13)
Airway responsiveness to histamine or methacholine: advances in measurement and interpretation. (1986) (13)
Airway hyperresponsiveness: using bronchial challenge tests in research and management of asthma. (2002) (13)
Effect of an inhaled neutral endopeptidase inhibitor, thiorphan, on airway responsiveness to leukotriene D4 in normal and asthmatic subjects. (1994) (13)
Effects of a high-protein diet in acid maltase deficiency (1989) (13)
Mild asthma in overweight women: A new phenotype? (2010) (12)
Adaptation of a difficult-to-manage asthma programme for implementation in the Dutch context: a modified e-Delphi (2017) (12)
Enhanced airway dilation by positive-pressure inflation of the lungs compared with active deep inspiration in patients with asthma. (2008) (12)
Urinary Eosinophil Protein X in Children with Atopic Asthma (2007) (12)
Bradykinin B2 receptor expression in the bronchial mucosa of allergic asthmatics: the role of NF‐kB (2016) (12)
Loss of adaptive capacity in asthmatic patients revealed by biomarker fluctuation dynamics after rhinovirus challenge (2019) (12)
Asthma control cost-utility randomized trial evaluation (ACCURATE): the goals of asthma treatment (2011) (12)
Volatile metabolites of pathogens – a Systematic review Plos Pathogens 2013 (2014) (12)
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Cigarette smoking and pulmonary diffusion defects in rheumatoid arthritis (1998) (11)
Repeated low dose allergen exposure: a new investigational model of asthma as a persistent disease? (1998) (11)
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Mapping atopic dermatitis and anti-IL-22 response signatures to Type 2-low severe neutrophilic asthma. (2021) (11)
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Instability of sputum molecular phenotypes in U-BIOPRED severe asthma (2020) (11)
Metabolic differences between bronchial epithelium from healthy individuals and asthma patients and the effect of bronchial thermoplasty. (2021) (11)
eNose breathprints as a surrogate biomarker for classifying asthma patients by atopy. (2020) (11)
The place of airway hyperresponsiveness in the asthma phenotype (1995) (11)
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The PDE4 inhibitor roflumilast reduces sputum neutrophil and eosinophil numbers in patients with COPD (2007) (10)
Lipid phenotyping of lung epithelial lining fluid in healthy human volunteers (2018) (10)
Hyperbaric oxygen diving affects exhaled molecular profiles in men (2014) (10)
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Urinary Eosinophil Protein X in Childhood Asthma: Relation with Changes in Disease Control and Eosinophilic Airway Inflammation (2013) (9)
Th2 subsetting of U-BIOPRED asthma subjects based on airway transciptomic profiles (2015) (8)
Towards identifying the susceptible smoker. (1981) (8)
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Reversal of the late asthmatic response increases exhaled nitric oxide. (2005) (7)
Airway Elastin is increased in severe asthma and relates to proximal wall area: histological and computed tomography findings from the U‐BIOPRED severe asthma study (2020) (7)
Lung function fluctuation patterns unveil asthma and COPD phenotypes unrelated to type 2 inflammation. (2021) (7)
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Lung function before and after oxygen diving: a randomized crossover study. (2012) (7)
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Metabolomics in Critically ill Patients: Focus on Exhaled Air (2012) (7)
Airway inflammation in COPD after long-term withdrawal of inhaled corticosteroids (2017) (7)
eNose breathprints as composite biomarker for real-time phenotyping of complex respiratory diseases. (2020) (7)
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Fast Assessment Of ALI/ARDS In The ICU Using Exhaled Breath Analysis (2010) (6)
Long-term follow-up after two years of asthma treatment guided by airway responsiveness in children. (2013) (6)
Relationship between atrial septal defects and asthma-like dyspnoea: the impact of transcatheter closure (2016) (6)
The Influence of Smoking Status on Exhaled Breath Profiles in Asthma and COPD Patients (2021) (6)
Reduction of airway smooth muscle mass after bronchial thermoplasty: are we there yet? (2015) (6)
Heterogeneity of airway hyperresponsiveness: time for unconventional, but traditional, studies. (2004) (6)
Targeted exhaled breath analysis for detection of Pseudomonas aeruginosa in cystic fibrosis patients. (2021) (6)
Small airways, big challenge (2011) (6)
Factors Influencing Continuous Breath Signal in Intubated and Mechanically-Ventilated Intensive Care Unit Patients Measured by an Electronic Nose (2016) (5)
Targeted exhaled breath analysis for detection of Pseudomonas aeruginosa in cystic fibrosis patients (2020) (5)
A Topological Data Analysis Network Model of Asthma Based on Blood Gene Expression Profiles (2019) (5)
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Automatic negative evaluation of suffocation sensations in individuals with suffocation fear. (2005) (5)
Increased day‐to‐day fluctuations in exhaled breath profiles after a rhinovirus challenge in asthma (2021) (5)
Use of Posterior Probabilities to Evaluate Methods of Discriminant Analysis (1981) (5)
Modern Inflammatory Phenotyping of Asthma. Breathomics Is Here to Stay (2019) (5)
How integration of global omics-data could help preparing for pandemics – a scent of influenza (2014) (5)
Serving researchers, the impact factor and other conflicts of interest (2005) (5)
Clinical features of bronchial hyperresponsiveness. (1999) (5)
The trials and tribulations of anti–IL-5 … (2002) (4)
Early detection of lung cancer in patients with COPD by eNose technology (2018) (4)
Unbiased clustering of children with asthma or pre-school wheeze using the U-BIOPRED electronic nose platform (2014) (4)
Medication adherence in patients with severe asthma prescribed oral corticosteroids in the U-BIOPRED cohort. (2021) (4)
Diagnostic Value Of Exhaled Breath Analysis In Tuberculosis (2012) (4)
Alterations of Exhaled Breath Metabolite – mixtures in Two Rat Models of Lipopolysaccharide – induced Lung Injury Journal of Applied Physiology 2013 (2014) (4)
The first U-BIOPRED blood handprint of severe asthma (2015) (4)
Atrial septal defect in adults is associated with airway hyperresponsiveness (2018) (4)
Doxycycline for exacerbations of chronic obstructive pulmonary disease in outpatients: who benefits? (2020) (4)
An Atlas of Induced Sputum : An Aid for Research and Diagnosis (2003) (4)
Erratum to: Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5) (2017) (4)
An electronic nose can distinguish between different asthma phenotypes (2013) (4)
Breath biomarkers in asthma: we're getting answers, but what are the important questions? (2019) (4)
Breathomics can discriminate between anti IgE-treated and non-treated severe asthma adults (2015) (4)
eNose analysis for early immunotherapy response monitoring in non-small cell lung cancer. (2021) (4)
Identification of exhaled volatile organic compounds (VOCs) associated with loss of asthma control (2016) (4)
Eosinophil progenitors in sputum: throwing out the baby with the bath water? (2004) (4)
Non-invasive breath monitoring with eNose does not improve glucose diagnostics in critically ill patients in comparison to continuous glucose monitoring in blood (2017) (4)
COVID-19 and beyond: a call for action and audacious solidarity to all the citizens and nations, it is humanity’s fight (2020) (4)
Doxycycline Added to Prednisolone in Outpatient-Treated Acute Exacerbations of COPD: A Cost-Effectiveness Analysis Alongside a Randomised Controlled Trial (2019) (4)
Long-term asthma treatment guided by airway hyperresponsiveness in children (2007) (4)
Emerging Complexity in the Biomarkers of Exacerbation-Prone Asthma (2020) (4)
Exploring The Potential Of Electronic Nose Measurements For Diagnosing Sarcoidosis (2012) (3)
Inflammatory phenotypes underlying uncontrolled childhood asthma despite inhaled corticosteroid treatment: rationale and design of the PACMAN2 study (2013) (3)
Proteomics in asthma: the clinicians were right after all, were not they? (2017) (3)
Asthmatic children that are uncontrolled despite inhaled corticosteroids have a distinct breathprint: Results of the PACMAN2 study (2015) (3)
Measures of adherence in patients with severe asthma prescribed systemic steroids in the U-BIOPRED cohort (2018) (3)
Clustering analysis of clinical variables in U-BIOPRED adult asthma cohort (2014) (3)
Nasal Polyposis Identifies An At Risk Phenotype Among Patients With Adult-Onset Asthma (2011) (3)
Ex vivo innate responses to particulate matter from livestock farms in asthma patients and healthy individuals (2020) (3)
AsthmaMap: an interactive knowledge repository for mechanisms of asthma. (2020) (3)
Identifying patients at risk for future exacerbations of asthma: Development of a prediction model (2015) (3)
Anti-IL5 in mild asthma alters rhinovirus-induced macrophage, B cell and neutrophil responses (2019) (3)
Exhaled molecular patterns change after experimental rhinovirus 16 infection in asthma (2011) (3)
eTRIKS IT platfroms for large-scale biomedical research (2015) (3)
An Electronic Nose Discriminates between the Exhaled Breath of Patients with Pleural Malignant Mesothelioma and Healthy Controls. (2009) (3)
Characteristics of asthma in U-BIOPRED severe and non-severe cohorts with distinct biomarker profiles (2015) (3)
Erratum: International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma (European Respiratory Journal (2014) 43 (343–373) DOI: 10.1183/09031936.00202013) (2018) (3)
STANDARDIZATION OF LUNG FUNTION TESTS EUROPEAN COMMUNITY FOR STEEL AND COAL OFFICIAL STATEMENT OF THE EUROPEAN RESPIRATORY SOCIETY (2012) (3)
Asthmatic children that are uncontrolled despite inhaled corticosteroids have a distinct breathprint (the pacman2 study) (2015) (3)
The secret life of steroids in asthma (2008) (3)
Effect Of Long Term Corticosteroid Treatment On Microrna And Gene Expression Profiles In Chronic Obstructive Pulmonary Disease (2015) (3)
Exhaled air volatile organic compounds and eosinophilic airway inflammation in asthma (2012) (3)
Sputum transcriptomics reveal up-regulation of IL-1 receptor family members in severe asthma. (2017) (3)
Identification of recent exacerbations in COPD patients by electronic nose (2020) (3)
A cluster randomized trial comparing strict, partial, and FeNO-guided asthma control strategies in primary care (2013) (3)
Assessment of repeatability of eNose (SpiroNose) measurements in healthy and asthmatic subjects (2018) (3)
Characteristics of the frequent exacerbator in U-BIOPRED adult severe asthma cohort (2015) (3)
Exhaled molecular pro fi les in the assessment of cystic fi brosis and primary ciliary dyskinesia ☆ (2013) (3)
Molecular evidence of Group 1 innate lymphoid cell activation in the U-BIOPRED cohort (2017) (2)
Bronchoscopic Air-sampling by Electronic Nose for molecular assessment Of Lung Cancer (2010) (2)
eNose Technology for Detection of Pseudomonas Aeruginosa Infection in Cystic Fibrosis Patients (2019) (2)
Late Breaking Abstract - Comparison of the blood transcriptomic profiles of adults and children from the U-BIOPRED asthma study (2017) (2)
Exhaled Breath Molecular Profiling Using an Electronic Nose Identifies Eosinophilic Inflammation in COPD. (2009) (2)
Novel Type 2-high gene clusters associated with corticosteroid sensitivity in COPD (2020) (2)
Virus Dependent Changes In Exhaled Molecular Profile In Wheezy Infants. Prospective Data From The EUROPA Study (2012) (2)
Impact of atrial septal defect closure on diffusing capacity for nitric oxide and carbon monoxide (2019) (2)
Exhaled Breath Molecular Profiles by Electronic Nose Can Discriminate Doctor-Confirmed Wheezy Infants from Controls. (2009) (2)
Erratum to: Building bridges for innovation in ageing: Synergies between action groups of the EIP on AHA (2016) (2)
Analysing exhaled breath during endovenous laser ablation of varicose veins using an electronic nose and gas chromatography-mass spectrometry (2013) (2)
LSC Abstract – Identifying biomarkers of loss of control/exacerbations in asthma from exhaled breath (2016) (2)
Reliability Of 'Doctor's Confirmed Wheeze' In Infants: Validation In The EUROPA Cohort (2011) (2)
Infection: friend or foe to the development of asthma? (2001) (2)
Systemic corticosteroid-associated serum analyte profiles in the U-BIOPRED severe asthma cohort (2015) (2)
Exhaled breath analysis for identifying eosinophilic and neutrophilic inflammation in a mixed population of patients with asthma or COPD (2016) (2)
Baseline and longitudinal urinary eicosanoid profiles for molecular sub-phenotyping in the U-BIOPRED study (2019) (2)
Exhaled Breath Analysis In The Diagnosis Of Acute Lung Injury (2011) (2)
Monitoring exhaled Nitric Oxide (FENO) To Tailor The Lowest Effective Dose Of Oral Corticosteroids In Severe Asthma (MONOSA-Study) (2010) (2)
Breathomics in asthma and COPD 5 (2016) (2)
Pre- and post-bronchodilator spirometric values and the degree of reversibility in patients with COPD. Author's reply (2004) (2)
A good asthma catch by professional fishing (2017) (2)
MMP10andMETas predictive classifiers of bronchial eosinophilic asthma in UBIOPRED (2015) (2)
Non-invasive monitoring of bronchial inflammation in asthma. (1997) (2)
Volatile Organic Compounds Breathprinting of U-BIOPRED Severe Asthma smokers/ex-smokers cohort (2017) (2)
Your 10,000 manuscripts (2008) (2)
Unbiased cluster analysis of severe asthma based on metabolomics by the U-BIOPRED electronic nose platform (2013) (2)
Discrimination between oral corticosteroid-treated and oral corticosteroid-non-treated severe asthma patients by an electronic nose platform (2014) (2)
A Genome Wide Association Study of Moderate-Severe Asthma in subjects from the United Kingdom (2017) (2)
A new series on airway remodelling (2007) (2)
ESICM LIVES 2016: part two (2016) (2)
U-BIOPRED accessible handprint: combining omics platforms to identify stable asthma subphenotypes (2018) (2)
LSC Abstract – The AsthmaMap: Towards a community-driven reconstruction of asthma-relevant pathways and networks (2016) (2)
Exhaled breath VOCs are associated with nocturnal wakening in asthmatic children (2015) (2)
Unbiased clustering of severe asthma patients based on exhaled breath profiles (2015) (2)
Asthma phenotyping: T H 2-high, T H 2-low, and beyond (2013) (2)
Single-breath diffusion: Comparison between helium and methane as tracer gases in COPD and healthy controls (2014) (2)
LATE-BREAKING ABSTRACT: Transcriptomic fingerprinting in severe adult-onset asthma shows type2-high and inflammatory-cell gene signatures in the U-BIOPRED cohort (2015) (2)
Longitudinal changes in exhaled breath GC/MS profiles during loss of asthma control by prospective steroid withdrawal (2015) (2)
Prediction of asthma in early preschool wheezing by electronic nose analysis (2021) (2)
Detection of Pseudomonas aeruginosa in exhaled breath of cystic fibrosis patients (2018) (2)
Local And Systemic Inflammatory Responses Following Low-Dose Bronchial Endotoxin Instillation In Mild Asthmatics (2011) (2)
CONTINUOUS EXHALED BREATH ANALYSIS ON THE ICU (2011) (2)
Pragmatic trials: how to adjust for the 'Hawthorne effect'? response (2012) (1)
30. Cell differentials in induced sputum after inhaled leukotriene D in subjects with mild, persistent asthma (1997) (1)
Smoking status and anti-inflammatory macrophages in induced sputum and bronchoalveolar lavage in COPD (2011) (1)
Late Breaking Abstract - Comparison of clinical characteristics between severe adult asthmatics in Brazil(ProAR) and Europe(U-BIOPRED) (2017) (1)
Coagulation activity increases with disease severity in patients with asthma (2015) (1)
Gene signatures from U-BIOPRED transcriptomic-associated clusters exist in COPD (2017) (1)
Anti-Inflammatory Macrophages in Ex-Smokers with COPD in Bronchoalveolar Lavage (BAL) and Sputum. (2009) (1)
Whole transcriptome analysis in peripheral blood from asthmatic and healthy subjects in the U-BIOPRED study (2014) (1)
Nose in malignant mesothelioma-Prediction of response to immune checkpoint inhibitor treatment. (2021) (1)
Successful Distinction between Asthma and COPD by Molecular Profiling of Exhaled Breath Using Electronic Nose. (2009) (1)
Imprinting of bronchial epithelial cells upon in vivo rhinovirus infection in people with asthma (2021) (1)
In memoriam: Frederick E Hargreave (1938–2011) (2011) (1)
Clinical Improvement In Patients With Severe Asthma At High Altitude Occurs Irrespective Of Allergy To House Dust Mite (2010) (1)
Clinical and histological comparison of smoking and non-smoking patients with severe asthma in the U-BIOPRED cohort (2014) (1)
Late Breaking Abstract - Cluster analysis of treatable traits in the U-BIOPRED adult severe asthma cohort (2017) (1)
NITRIC OXIDE AND RESPONSE TO INHALED BRADYKININ IN SEVERE ASTHMA. AUTHORS'REPLY (1998) (1)
Airway Gene Expression as a Molecular Phenotype of COPD (2012) (1)
Airway physiology and pathophysiology in severe asthma (2011) (1)
Correction for de Heer et al., Detection of Airway Colonization by Aspergillus fumigatus by Use of Electronic Nose Technology in Patients with Cystic Fibrosis (2016) (1)
Association of endopeptidases, involved in SARS‐CoV‐2 infection, with microbial aggravation in sputum of severe asthma (2021) (1)
Cardiac Arrhythmia Induced Cough: Demonstrable But Not Clinically Significant In Chronic Cough (2012) (1)
Abstracts from the 3rd International Severe Asthma Forum (ISAF) (2017) (1)
Biomarker discovery for asthma phenotyping : From gene expression to the clinic (2015) (1)
Late Breaking Abstract - Technical validation of breath analysis by eNose in disease diagnosis: Tidal breathing vs. vital capacity manoeuvre (2019) (1)
Relationship between blood eosinophil count and bronchial epithelial gene expression in COPD versus Asthma (2018) (1)
Late Breaking Abstract - Detection of clinical instability by eNose in COPD patients (2018) (1)
eNose breathprints as surrogate biomarkers for classifying asthma patients by atopy (2019) (1)
Effect of summertime air pollution on acute respiratory symptoms and lung function in mild to severe asthmatics. (1997) (1)
Patient-reported clinical control and peak-flow: Effects of 30 versus 6 month treatment with inhaled corticosteroids (ICS) with/without long-acting2-agonists (LABA) in moderately severe COPD (2009) (1)
FKBP5 a candidate for corticosteroid insensitivity in COPD (2016) (1)
Exhaled Molecular Profiles In The Diagnosis Of Cystic Fibrosis And Primary Ciliary Dyskinesia (2012) (1)
Modelling electronic nose sensor deflections by matching Gas Chromatography-Mass Spectrometry exhaled breath samples (2019) (1)
Airway Hyperresponsiveness to Mannitol Is Associated with Markers of Airway Inflammation in Patients with COPD. (2009) (1)
Changes In Gene Expression Profiles Induced By DsRNA And Allergen In Primary Nasal And Bronchial Epithelial Cells Of Patients With Asthma And Controls (2012) (1)
Unsupervised and externally validated clinical cluster analysis from the U-BIOPRED paediatric cohorts (2018) (1)
Translation of in vitro findings to patients with asthma: a timely and compelling challenge (2019) (1)
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PATHOPHYSIOLOGY OF ASTHMA (2000) (1)
pulmonary disease Flt-1 ) in patients with chronic obstructive andendothelial growth factor and receptors ( Flk-1 Enhanced bronchial expression of vascular (2005) (1)
Detection of Pseudomonas aeruginosa infection in cystic fibrosis patients by eNose technology (2018) (1)
Detection of invasive aspergillosis by an electronic nose platform: Preliminary data in a validation cohort (2014) (1)
Anti-IgE Treatment Improves Lung Function In Patients With Mild Persistent Allergic Asthma (2006) (1)
Exhaled Breath Molecular Profiling In The Differential Diagnosis between Asthma With Fixed Airways Obstruction And COPD: External Validation (2010) (1)
Exclusion of asthma for screening purposes using exhaled air molecular profiling by electronic nose (2011) (1)
In memoriam Professor Paul Vermeire, 1936–2007: a tribute from the ERJ Chief Editors (2007) (1)
The Effect of Tiotropium Bromide on Deep Inspiration-Induced Bronchodilation and Airway Responsiveness in Asthma. (2009) (1)
Weighted Gene Co-expression Network Analysis of blood paediatric samples from the U-BIOPRED study identifies oxidative stress association with asthma severity (2018) (1)
Iconographies supplémentaires de l'article : Severe adult-onset asthma: A distinct phenotype (2013) (1)
Rhinovirus Challenge in Asthmatics and Healthy Volunteers to Evaluate the Safety and Appropriate Dose of a GMP Human Rhinovirus 16 Preparation for Challenge Studies in Mild-Moderate Asthmatics taking ICS (2018) (1)
Predictive performance of non-invasive Type 2 biomarkers for asthmatic sputum eosinophilia in Bobcat and U-Biopred studies (2016) (1)
Limited Maximal Airway Narrowing in Nonasthmatic Subjects (2015) (1)
Proteome fingerprints define groups with distinct clinico-pathological phenotypes in the U-BIOPRED asthma study (2016) (1)
Topological data analysis (TDA) of U-BIOPRED paediatric peripheral blood gene expression identified asthma phenotypes characterised by alternative splicing of glucocorticoid receptor (GR) mRNA (2018) (1)
Chronic obstructive pulmonary disease phenotypes: current rather than future perspectives. (2012) (1)
Patterns of Daily Exhaled Nitric Oxide (FENO) in Severe, Steroid-Dependent Asthma. (2009) (1)
Pathogenesis and treatment of asthma (2002) (1)
Identification Of Micrornas That Potentially Regulate Chronic Mucus Hypersecretion In COPD (2016) (1)
Associated factors with persistent airflow limitation in asthma in U-BIOPRED (2013) (1)
How to achieve safe, high-quality clinical studies with non-Medicinal Investigational Products? A practical guideline by using intra-bronchial carbon nanoparticles as case study (2016) (1)
Identification of atopy amongst wheezing infants via electronic nose (2014) (1)
Nitric oxide and response to inhaled bradykinin in severe asthma (1998) (1)
Leukotriene Receptor Antagonists and Biosynthesis Inhibitors in Asthma (1994) (1)
Local coagulation activation following bronchial instillation of house dust mite allergen (HDM) and HDM/Lipopolysaccharide (LPS) in mild asthmatics (2012) (0)
Prediction of wheeze recurrence and severity in infants by composite epidemiological score (2013) (0)
Is the average exhaled nitric oxide concentration (FeNO) effective in detecting respiratory rhinovirus (RV) infections? (2020) (0)
Towards Prospective Criteria For Asthma Exacerbations: When Do General Practitioners Start Systemic Corticosteroids? (2011) (0)
U-BIOPRED asthma cohort: Inflammatory markers and corticosteroid use (2013) (0)
Airway Gene Expression Is Dynamic With Inhaled Corticosteroid Treatment And Reflects Clinical Response In Patients With COPD (2012) (0)
Extracellular Matrix Components Within Airway Smooth Muscle In Asthma: Histopathology And Airway Function (2010) (0)
Evaluation of the effect of sampling of spontaneous sputum over a prolonged period on the sensitivity for lung cancer (2011) (0)
Nitric oxide and response to inhaled bradykinin in severe asthma (multiple letters) (1998) (0)
Understanding Pulmonary Diseases An Integrative Systems Biology Approach to (2010) (0)
bronchial inflammation in COPD Relation between duration of smoking cessation and (2006) (0)
Morse-clustering of a Topological Data Analysis Network Identifies Phenotypes of Asthma Based on Blood Gene Expression Profiles (2019) (0)
Urinary metabolomics-based molecular sub-phenotyping of the U-BIOPRED asthma cohort (2017) (0)
Airway remodelling in the U-BIOPRED severe asthma cohort (2015) (0)
Strategies for tailoring asthma treatment in adults. (2013) (0)
U-BIOPRED: Clinical characteristics of children with severe asthma (SA) and severe pre-school wheeze (SPSW) (2014) (0)
Clinical Presentation Of Newly Diagnosed Adult-onset Asthma (2010) (0)
LATE-BREAKING ABSTRACT: Sputum transcriptome analysis yields eosinophilic and non-eosinophilic inflammatory mechanisms in UBIOPRED asthma cohort (2015) (0)
Effect of Bronchodilation on Smell-Prints of Exhaled Breath in Asthmatic Patients Assessed by Electronic Nose (eNose). (2009) (0)
UvA-DARE ( Digital Academic Repository ) Human enteroviruses and parechoviruses : disease spectrum and need for treatment in young children (2014) (0)
T17 gene asthma signature characterized by sputum neutrophilia and regular use of antibiotics (2017) (0)
Exhaled breath analysis discriminates phenotypes of acute lung injury (ALI) (2012) (0)
Forced oscillation technique: an alternative outcome measure for methacholine provocation test (2017) (0)
Versican and collagen-III expression in bronchial and pulmonary muscular arteries in COPD patients (2015) (0)
Only in non-obese patients with COPD MEF50 is strongly associated with dynamic hyperinflation (2014) (0)
Inducible Expression Quantitative Trait Loci (2016) (0)
The role of food allergy in adult onset asthma (2011) (0)
Discordant use of short‐acting β2 agonists in children and adults with severe, uncontrolled asthma from the U‐BIOPRED cohort (2020) (0)
Reply: Complexity Analysis of Respiratory Dynamics. (2017) (0)
Use of Pulmonary Inhalants Remains Remarkably High After Atrial Septal Defect Closure. (2018) (0)
The airway smooth muscle in asthma : More than meets the eye (2013) (0)
The trials and tribulations of anti-IL-5 em leader. (2002) (0)
Subphenotyping COPD using breath profiles COPD subphenotypes by combining pulmonary function, CT imaging and breathomics in cluster analysis. A population-based survey (2011) (0)
Tapering oral corticosteroids in severe asthma is associated with a decrease in fractional exhaled nitric oxide (2011) (0)
Lung Function in Active Smokers (1982) (0)
inspiration in patients with asthma inflation of the lungs compared with active deep Enhanced airway dilation by positive-pressure (2015) (0)
Phenotyping COPD: Association Between exhaled molecular Profiles And Inflammatory Biomarkers In Sputum And Blood (2010) (0)
Chronic rhinosinusitis and airway inflammation in new onset asthma in adults (2011) (0)
Macrophage Heterogeneity and Soluble Mediators in Sputum And Bronchoalveolar Lavage from Current Smokers And Ex-smokers With COPD (2010) (0)
De rol van groeifactoren en extracellulaire matrix regulatoren in luchtweg remodeling in COPD (1998) (0)
Correction: Susceptibility to Chronic Mucus Hypersecretion, a Genome Wide Association Study (2015) (0)
COVID-19 and beyond: a call for action and audacious solidarity to all the citizens and nations, it is humanity’s fight [version 1; peer review: awaiting peer review] (2020) (0)
LSC - 2019 - Anti-IL5 in mild asthma alters rhinovirus-induced macrophage, B cell and neutrophil responses (2019) (0)
Human rhinovirus (HRV) 16 infection in mild asthmatics induces an influx of neutrophils and increased expression of IL-8 in the nasal mucosa (1997) (0)
[Asthma: theory and practice in the year 1992]. (1992) (0)
A Bronchial Airway Gene Expression Signature Of COPD That Is Reflective Of Lung Tissue Disease Processes And Is Reversible With Inhaled Steroids (2012) (0)
Hyperinflation and health status contribute to 6-minute walk distance in COPD, contrary to airway inflammation (2011) (0)
Volatile organic compounds concentrations in the exhaled breath of ventilated ICU-patients are different between patients with pneumonia, colonized airways and controls. (2014) (0)
Regulatory T cells in healthy and asthmatic subjects challenged with rhinovirus (2011) (0)
Bradykinin and exhaled nitric oxide in asthma. (2002) (0)
Peak Expiratory Flow Rate, Symptom Score, and Medical Use in Patients With Asthma or Chronic Airflow Limitation Before and 1 Year After a Stay in the Alpine Climate (1994) (0)
Breathomics in pulmonary disease Fens (2011) (0)
Bos ICM Letter VAP headspace Supplement (2014) (0)
Unbiased clinical cluster analysis across a combined European and a Brazilian severe asthma (SA) population. (2018) (0)
Within-Breath Fluctuations of Respiratory Impedance under Methacholine Challenge in Asthma. (2009) (0)
Antibiotics For Treating COPD-Exacerbations In An Out-Of-Hours Setting: Clinical Practice Versus Guidelines (2011) (0)
Association between Respiratory Viral Infections and Lung Function Decline in Asthma. (2009) (0)
The complex association of pulmonary function with panic disorder: a rejoinder to Ley (1998). (1999) (0)
Remodeling of bronchial and pulmonary muscular arteries in mild/moderate COPD (2014) (0)
Periostin expression in the U-BIOPRED severe asthma bronchoscopy cohort (2018) (0)
Serum pregnancy-associated plasma protein A (PAPPA) as a predictor of eosinophilic Type-2 high asthma (2021) (0)
Clinical determinants for oral steroids during COPD-exacerbations in primary care (2011) (0)
Posture Dependent Expiratory Flow Limitation In Obese Subjects Measured By Within-Breath Forced Oscillation Technique (2011) (0)
The Additive Effect Of Salmeterol To Inhaled Corticosteroids On House Dust Mite (HDM) ± Lipopolysaccharide Induced Pulmonary Inflammation In Patients With Mild Asthma (2012) (0)
Distinct pathways underlying neutrophilic inflammation in smoking-associated severe asthma in U-BIOPRED (2017) (0)
Cluster Analysis Identifies COPD Subphenotypes By Combining Pulmonary Function, CT Imaging And Breathomics (2011) (0)
Lumican And Biglycan Expression In Lungs Of COPD Patients (2010) (0)
Late Breaking Abstract - Microbiome-driven clusters in severe asthma derived from induced sputum: identification and stability over time (2019) (0)
Poly(I:C)-induced responses in nasal and bronchial epithelial cells of patients with asthma and healthy controls (2011) (0)
Fluctuation Dynamics of Clinical Markers in Asthmatic and Healthy Subjects Challenged with Rhinovirus (2017) (0)
Authors' response (2011) (0)
Respiratory medicine (2020) (0)
Added Value Of Exhaled Breath Analysis To Viral Profiling And Atopy In The Phenotyping Of Infants With Confirmed Wheeze (2011) (0)
Biomarkers and exacerbations of asthma and COPD (2011) (0)
Future directions (2002) (0)
Bias in Laboratory Animal Research : A Survey on Magnitude , Drivers , Consequences and Potential Solutions (2017) (0)
Exhaled breath metabolomics as a non – invasive diagnostic tool for ARDS European Respiratory Journal 2014 (2014) (0)
[Novel treatment of bronchial asthma: application of leukotriene receptor antagonists and leukotriene synthesis inhibitors]. (1998) (0)
In memoriam Maurizio Vignola (2005) (0)
Extracellular Matrix Within Airway Smooth Muscle And Dynamics Of Airway Function In Asthma And Atopy (2011) (0)
Pulmonary , gastrointestinal and urogenital pharmacology Bradykinin-induced asthmatic fi broblast / myo fi broblast activities via bradykinin B 2 receptor and different MAPK pathways (2013) (0)
Effects of cigarette smoke on bronchial epithelium: implications for asthma (2002) (0)
Real TimeIn VitroClassification of CF-DerivedStaphylococcus aureusandPseudomonas aeruginosaby Electronic Nose. (2009) (0)
Subtypes of eosinophilic asthma with discrete gene pathway phenotypes (2019) (0)
P047 Detection of Pseudomonas aeruginosa in exhaled breath of cystic fibrosis patients (2018) (0)
Interferon response genes in nasal epithelium to RV16 challenge in asthma patients links to viral clearance and common cold scores (2019) (0)
Maximal Airway Narrowing in Humans in vivo (2015) (0)
Indoleamine 2,3-dioxygenase and virus-induced exacerbations in asthma (2008) (0)
UvA-DARE (Digital Academic Repository) Diagnosis of pulmonary injury and infection by exhaled breath analysis Bos, L.D.J (2014) (0)
The first U-BIOPRED sputum handprint of severe asthma (2015) (0)
Characteristics of the adult corticosteroid-dependent severe asthma in UBIOPRED consortium (2014) (0)
[Symbols, abbreviations and units. Work Group on Standardization of Respiratory Function Tests. European Community for Coal and Steel. Official position of the European Respiratory Society]. (1994) (0)
e-Nose art (2016) (0)
Change in glucocorticoid sensitivity of peripheral blood leukocytes after strenous exercise (1997) (0)
1 Biomarkers in asthma and allergic rhinitis (2018) (0)
Increased Activation Of Coagulation In Patients With Mild Asthma After Rhinovirus Infection (2012) (0)
Cross-sectional biomarker comparisons with a longitudinal perspective in asthma monitoring: the eNose premise (2020) (0)
COVID-19 and Beyond: A Call for Action and Audacious Solidarity to All the Citizens and Nations, It Is Humanity’s Fight (2020) (0)
Author's response to reviews Title: Inflammatory phenotypes underlying long-term uncontrolled childhood asthma: Rationale and design of the PACMAN2 study Authors: (2013) (0)
Electronic nose breathprints reflect BALF inflammatory cell counts in asthma (2013) (0)
OF WORKING GROUP 1 Sputum induction Leader of the Working Group : P . L . Paggiaro * Members of the Working Group : (2002) (0)
Structure-function relationship between extracellular matrix in airway smooth muscle and dynamics of lung function in asthma (2011) (0)
Effects Of Smoking Status And Inhaled Corticosteroids On Extracellular Matrix Proteins In Bronchial Biopsies Of COPD Patients (2011) (0)
Urinary metabolomics-profiling of the U-BIOPRED asthma study identified biochemical clusters associated with asthma severity (2020) (0)
Contents, vol. 50, Supplement 2, 1986 (1986) (0)
Is there a need for higher doses of steroids in moderate asthma (2001) (0)
Diagnostic accuracy of markers for detection of airway eosinophilia in asthma: A systematic review (2014) (0)
"COPD-Lite": do you like the taste? (2011) (0)
Systemic coagulation increases with asthma severity (2014) (0)
[Hyperventilation: not a cause of panic attacks]. (1993) (0)
Local and systemic inflammatory responses following bronchial instillation of house dust mite allergen (HDM) and HDM/lipopolysaccharide (LPS) in mild asthmatics (2011) (0)
Late Breaking Abstract - Longitudinal analysis of variation in clinical features from the U-BIOPRED severe asthma cohort (2018) (0)
Combined analysis of gene expression and clinical data in the severe asthma U-BIOPRED cohorts (2014) (0)
Loss of adaptive capacity in asthmatics revealed by biomarker fluctuation dynamics upon experimental rhinovirus challenge (2019) (0)
Targetted therapy for virus-induced exacerbations in asthma (2011) (0)
Intracerebral hemorrhage in ICU: is it worth treating? (2016) (0)
Longitudinal Replication Of Severe Asthma Exhaled Breath Phenotypes By The U-Biopred Electronic Nose Platform (2016) (0)
Association between rhinovirus C infection and respiratory symptom severity in an unselected pediatric population, the EUROPA-study (2012) (0)
Gladspierweeefsel fenotype in de luchtwegen en de klinische expressie van astma (2009) (0)
The Effect of Bronchial Challenge Testing on Exhaled Breath Molecular Profile by Electronic Nose in Asthma Patients. (2009) (0)
Lipid biomarkers predictive of gastro-oesophageal reflux in adult asthma (2016) (0)
List of principal contributors (2003) (0)
Exhaled Breath Analysis for Prediction of Response to Anti-PD1 Therapy in Patients with NSCLC (2017) (0)
Association between exhaled volatile organic compounds and urinary levels of oral corticosteroids within the U-BIOPRED Cohort (2018) (0)
Improving aasthma ttreatment: tthe pphysiological m message (1994) (0)
Diagnostic Value Of Plasma Tryptophan Level In Allergic Asthma Patients (2012) (0)
asthmatic children . exercise-induced bronchoconstriction in Sample size estimation in studies monitoring (1998) (0)
Correction to: Sputum ACE2, TMPRSS2 and FURIN gene expression in severe neutrophilic asthma (2021) (0)
Late Breaking Abstract - Day-to-day variability in exhaled breath profiles of asthmatic patients and healthy volunteers challenged with a rhinovirus (2019) (0)
The way forward in asthma: integrative physiology. (1998) (0)
Psychological Factors Contributing To Asthma Control And Asthma Related Quality Of Life In Patients With Severe Prednisone-Dependent Asthma (2011) (0)
Diagnosis of pulmonary injury and infection by exhaled breath analysis (2014) (0)
Asthma and respiratory pathogens (2007) (0)
Metabolic differences in bronchial epithelium from asthma patients and impact of bronchial thermoplasty (2020) (0)
AGREEMENTS AND DISAGREEMENTS IN RESULTS OF EPIDEMIOLOGICAL INVESTIGATIONS WITH QUESTIONNAIRES AND SPIROMETRIC LUNG-FUNCTION TESTS (1982) (0)
healthy subjects with airway smooth muscle activation and unloading Short-term variability in respiratory impedance and effect of deep breath in asthmatic and (2015) (0)
Supplement: The roots of allergic sensitization - Proceedings of the Fourth Lunteren Symposium - Introduction (2000) (0)
Isolation of High Quality RNA from the Airway Smooth Muscle in Human Bronchial Biopsy Specimens: A Feasibility Study. (2009) (0)
Parent administered questionnaire captures presence and severity of doctor confirmed wheeze in infants (2011) (0)
Asthma and Wheeze Severity and the Oropharyngeal Microbiota in Children and Adolescents. (2022) (0)
Multivariate cluster analysis of immunopathological and clinical data from the U-BIOPRED severe asthma study: Preliminary results (2015) (0)
From the Editors (2004) (0)
1068: ICU ADMISSIONS AMONG PATIENTS WITH MILD TO SEVERE COPD: RESULTS FROM THE TEXACOLD STUDY (2016) (0)
Transmission of blood- borne viruses after motor- car accidents (1998) (0)
Urinary LTE4 may be associated with TH2-driven asthma: Initial data from the Pan-European U-BIOPRED IMI project (2014) (0)
Upper And Lower Airway Epithelial Responses To Synthetic Viral DsRNA In Patients With Asthma, Rhinitis And Control Subjects (2011) (0)
Asthma guidelines: to w ards ev idenc e-b ased applic atio n o f peak flo w (2006) (0)
Improved validity of cellular and molecular biomarkers from whole induced sputum in asthma and COPD (2008) (0)
Prevalence Of Sino-Nasal Diseases In New Onset Asthma In Adults (2011) (0)
The ability of the eNose on the discrimination of smoking status in asthma and COPD (2020) (0)
Low-dose Rhinovirus (RV16) Challenge In Allergic Asthma Patients Is Sufficient To Induce Clinical Signs Of A Mild Exacerbation (2010) (0)
diseasein patients with chronic obstructive pulmonary endothelial growth factor and receptors (Flk-1 and Enhanced bronchial expression of vascular (2006) (0)
breath in humans Effects of ventilation on the collection of exhaled (2015) (0)
Farewell to "CARA"? (1994) (0)
Temporal Fluctuations of Electronic Nose Signatures in Patiens with Asthma and Healthy Controls Challenged With Rhinovirus (2018) (0)
Late Breaking Abstract - ENose based phenotyping of newly presented patients with asthma or COPD (2018) (0)
The U-BIOPRED severe asthma study: Immunopathological characterisation (2014) (0)
Mast cell gene signature enrichment associates with late-onset severe asthma (2016) (0)
PRS43 - COST-EFFECTIVENESS OF DOXYCYCLINE VERSUS PLACEBO IN OUTPATIENT-TREATED ACUTE EXACERBATIONS OF COPD: A DOUBLE-BLIND RANDOMIZED CONTROLLED TRIAL (2018) (0)
MiR-320d: A novel anti-inflammatory miRNA up regulated by corticosteroids (2015) (0)
Headspace volatile trapping and analysis facility (2013) (0)
Assessing inflammation in COPD: (Non-)invasive methods (2013) (0)
Confirmed wheezing in infancy as basis for molecular fingerprinting in the prediction of asthma (2009) (0)
Antibiotics in exacerbations of asthma (2011) (0)
Further resolution of non-T2 asthma subtypes from high-throughput sputum transciptomics data in U-BIOPRED (2018) (0)
spectrometry: a feasibility study Analyses of mouse breath with ion mobility (2015) (0)
Patient-Reported Clinical Control and Peak-Flow (2009) (0)
Linking Gene Signatures with Eosinophil Cell Counts Thresholds for Severe Asthma Endotypes, from Bronchial to Blood (2019) (0)
exhaled air in mild asthma Small airways function and molecular markers in (2005) (0)
P3.02c-052 Electronic Nose: An Early Response Biomarker for Anti-PD1 Therapy in Patients with NSCLC: Topic: IT (2017) (0)
TNFAIP3 (A20) expression is elevated in the sputum of severe asthmatics (2016) (0)
Next-gen transcriptome analysis (RNA-Seq) of human bronchial biopsies and laser microdissected airway smooth muscle: Asthma vs. controls (2012) (0)
THORAXJNL153643 910..917 (0)
Breatheomics in the phenotyping and monitoring of asthma and COPD (2007) (0)
Intermittent versus continuous treatment with inhaled corticosteroids in COPD (1998) (0)
Rhinovirus infection activates coagulation through eosinophilic airway inflammation (2012) (0)
Towards molecular diagnosois in exhaled air (2007) (0)
Risk Factors Of Asthma Onset In Adulthood (2012) (0)
Differential mast cell activation by transcriptomic signature analysis in the U-BIOPRED severe asthma cohort (2020) (0)
Physiology of severe vs. mild-moderate U-BIOPRED cohorts interpreted using a computational model (2015) (0)
UvA-DARE ( Digital Academic Repository ) Comparison of exhaled breath condensate pH using two commercially available devices in healthy controls , asthma and COPD patients (2009) (0)
Next-Generation Transcriptome Sequencing (RNA-Seq) Of Whole Human Endobronchial Biopsies And Laser Dissected Airway Smooth Muscle: Asthma Versus Healthy Controls (2012) (0)
Expression of versican in large and small airways and parenchima in lungs of non-smokers smokers and COPD patients (2009) (0)
Enrichment of the Janus kinase (JAK) activation signature in severe asthma sputum: Correlation with IL-13 expression (2016) (0)
Adult onset asthma: the first 5 years (2009) (0)
Molecular Profiling of Exhaled Breath for Detection of Cystic Fibrosis in Children. (2009) (0)
Elastic Fiber Density in Large and Small Airways and Parenchyma in Lungs of Non-Smokers, Smokers and COPD Patients. (2009) (0)
The temporal stability of coagulation and fibrinolytic factors in patients with asthma and healthy subjects (2015) (0)
Airway Pathology in Smoking Asthmatics Is Characterized by CD8+ T Cells and Epithelial Changes. (2009) (0)
No Evidence of Respiratory Viral Infections in Patients with Stable Asthma as Determined by Non-Invasive Techniques. (2009) (0)
Glycoproteins In Large And Small Airways And In Lung Parenchyma Of COPD Patients (2011) (0)
unconventional, but traditional, studies Heterogeneity of airway hyperresponsiveness: time for (2015) (0)
P2602Airway hyperresponsiveness is associated with secundum atrial septal defects in adults (2018) (0)
ADEPT-derived, U-BIOPRED validated asthma clinical clusters with Th2 and non-Th2 phenotypes (2014) (0)
Constant Work Treadmill Test as a New Endpoint in Pulmonary Hypertension. (2009) (0)
Towards A Safe And Efficacious Model For Human Challenge With Carbon Black Nanoparticles (2010) (0)
Weekly self-monitoring and treatment adjustment benefi t patients with partly controlled and uncontrolled asthma (2010) (0)
Relationship between mitochondrial function and cellular ageing depends upon compartment analysed (2016) (0)
Eleventh Meeting of the European Venous Forum: Antwerp, Belgium, 24–26 June 2010 (2010) (0)
Sputum supernatant profiling reveals inflammasome-associated signatures in severe asthmatics in U-BIOPRED (2015) (0)
Macrophage migration inhibitory factor promotes glucocorticoid resistance of neutrophilic inflammation in a murine model of severe asthma. (2022) (0)
Repeated breath profiling by eNoses identifies asthma exacerbations and airway eosinophilia (2014) (0)
COPD subphenotypes in a population-based survey by factor and cluster analysis (2012) (0)
Increased incidence of pulmonary embolism in severe asthma (2011) (0)
Novel Adult-Onset Asthma Subphenotypes Using Cluster Analysis (2012) (0)
Airway smooth muscle fenotype and the clinical expression of asthma (2009) (0)
Using exhaled breath profiles in the discrimination between COPD, lung cancer and their co-morbidity (2015) (0)
monitoring in adolescents with asthma Compliance and reliability of electronic PEF (2006) (0)
Sputum transcriptomics identifies co-expressed network signatures associated with Fev1 and sputum neutrophilia in severe asthmatics on oral corticosteroids (2016) (0)
Mannose binding lectin (MBL) levels predict lung function decline in severe asthma (2006) (0)
Male Gender And Absence Of Atopy Are Associated With Persistent Airflow Limitation In Adult Onset Asthma (2010) (0)
Beyond airway disease: the value of breath tests in acute pulmonary embolism, a proof-of-principle study Breathomics as a diagnostic tool for pulmonary embolism (2011) (0)
LSC Abstract – Eicosanoids in asthma: Multi-omics data interpretation (2016) (0)
Electronic Nose Sensor Responses Are Repeatable When Measuring a Stable VOC Mixture. (2009) (0)
Effect Of Long Term Corticosteroid Treatment On Microrna And Gene Expression Profiles In Chronic Obstructive Pulmonary Disease: Transcriptomics Of The Glucold Study (2015) (0)
Phenotypes of adult-onset asthma by cluster analysis (2012) (0)
COVID-19 and beyond: a call for action and audacious solidarity to all the citizens and nations, it is humanity’s fight [version 1; peer review: 3 approved with reservations] (2021) (0)

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