Peter J. Novick
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Peter J. Novickbiology Degrees
Biology
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Molecular Biology
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Neuroscience
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Biochemistry
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Biology
Peter J. Novick's Degrees
- Bachelors Biology Stanford University
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(Suggest an Edit or Addition)Peter J. Novick's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway (1980) (1728)
- Role of Rab GTPases in membrane traffic and cell physiology. (2011) (1320)
- A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector. (1987) (1101)
- Rabs and their effectors: Achieving specificity in membrane traffic (2006) (1027)
- The Exocyst is a multiprotein complex required for exocytosis in Saccharomyces cerevisiae. (1996) (852)
- A ras-like protein is required for a post-Golgi event in yeast secretion (1987) (821)
- The diversity of Rab proteins in vesicle transport. (1997) (793)
- Order of events in the yeast secretory pathway (1981) (753)
- Phosphoinositides as Regulators in Membrane Traffic (1996) (731)
- The exocyst is an effector for Sec4p, targeting secretory vesicles to sites of exocytosis (1999) (644)
- A GTP-binding protein required for secretion rapidly associates with secretory vesicles and the plasma membrane in yeast (1988) (522)
- Secretion and cell-surface growth are blocked in a temperature-sensitive mutant of Saccharomyces cerevisiae (1979) (509)
- Phenotypic analysis of temperature-sensitive yeast actin mutants (1985) (503)
- Sec3p Is a Spatial Landmark for Polarized Secretion in Budding Yeast (1998) (384)
- Sec9 is a SNAP-25-like component of a yeast SNARE complex that may be the effector of Sec4 function in exocytosis (1994) (378)
- Friends and family: The role of the rab GTPases in vesicular traffic (1993) (356)
- A protein interaction map for cell polarity development (2001) (341)
- Spatial regulation of the exocyst complex by Rho1 GTPase (2001) (339)
- The role of Myo2, a yeast class V myosin, in vesicular transport (1995) (338)
- Sec1p Binds to Snare Complexes and Concentrates at Sites of Secretion (1999) (334)
- Sec2p Mediates Nucleotide Exchange on Sec4p and Is Involved in Polarized Delivery of Post-Golgi Vesicles (1997) (331)
- The yeast phosphatidylinositol-4-OH kinase Pik1 regulates secretion at the Golgi (1999) (329)
- Sec6, Sec8, and Sec15 are components of a multisubunit complex which localizes to small bud tips in Saccharomyces cerevisiae (1995) (321)
- GTPase networks in membrane traffic. (2012) (319)
- Homologs of the synaptobrevin/VAMP family of synaptic vesicle proteins function on the late secretory pathway in S. cerevisiae (1993) (314)
- Vesicles carry most exocyst subunits to exocytic sites marked by the remaining two subunits, Sec3p and Exo70p (2004) (310)
- Cdc42 Interacts with the Exocyst and Regulates Polarized Secretion* (2001) (310)
- The exocyst defrocked, a framework of rods revealed (2006) (297)
- Suppressors of yeast actin mutations. (1989) (279)
- Compartmentalized assembly of oligosaccharides on exported glycoproteins in yeast (1981) (264)
- Mutational analysis of SEC4 suggests a cyclical mechanism for the regulation of vesicular traffic. (1989) (263)
- Ypt32 recruits the Sec4p guanine nucleotide exchange factor, Sec2p, to secretory vesicles; evidence for a Rab cascade in yeast (2002) (263)
- Mutations in the SAC1 gene suppress defects in yeast Golgi and yeast actin function (1989) (226)
- Protein complexes in transport vesicle targeting. (2000) (222)
- The GTP-binding protein Ypt1 is required for transport in vitro: the Golgi apparatus is defective in ypt1 mutants (1989) (211)
- Exo84p Is an Exocyst Protein Essential for Secretion* (1999) (206)
- GDI1 encodes a GDP dissociation inhibitor that plays an essential role in the yeast secretory pathway. (1994) (206)
- Myo4p and She3p are required for cortical ER inheritance in Saccharomyces cerevisiae (2003) (192)
- The role of GTP-binding proteins in transport along the exocytic pathway. (1993) (187)
- Interactions of three domains distinguishing the Ras-related GTP-binding proteins Ypt1 and Sec4 (1993) (185)
- Ordering the Final Events in Yeast Exocytosis (2000) (178)
- Construction and genetic characterization of temperature-sensitive mutant alleles of the yeast actin gene. (1984) (174)
- Purification and characterization of constitutive secretory vesicles from yeast (1987) (166)
- A Rab GAP cascade defines the boundary between two Rab GTPases on the secretory pathway (2009) (166)
- Exocyst is involved in cystogenesis and tubulogenesis and acts by modulating synthesis and delivery of basolateral plasma membrane and secretory proteins. (2000) (161)
- Spatial Regulation of Exocytosis: Lessons from Yeast (1998) (160)
- ER structure and function. (2013) (147)
- Phosphatidylinositol 4-phosphate controls both membrane recruitment and a regulatory switch of the Rab GEF Sec2p. (2010) (147)
- Dynamics and inheritance of the endoplasmic reticulum (2004) (144)
- The structures of exocyst subunit Exo70p and the Exo84p C-terminal domains reveal a common motif (2005) (141)
- Rtn1p is involved in structuring the cortical endoplasmic reticulum. (2006) (137)
- The Yeast Class V Myosins, Myo2p and Myo4p, Are Nonprocessive Actin-Based Motors (2001) (135)
- The Sec15 protein responds to the function of the GTP binding protein, Sec4, to control vesicular traffic in yeast (1989) (132)
- Ras family therapy: Rab, Rho and Ral talk to the exocyst. (2002) (132)
- Geranylgeranylated Snares Are Dominant Inhibitors of Membrane Fusion (2000) (126)
- Sec3p is needed for the spatial regulation of secretion and for the inheritance of the cortical endoplasmic reticulum. (2003) (122)
- Hydrolysis of GTP by Sec4 protein plays an important role in vesicular transport and is stimulated by a GTPase-activating protein in Saccharomyces cerevisiae. (1992) (122)
- Role of actin and Myo2p in polarized secretion and growth of Saccharomyces cerevisiae. (2000) (120)
- Export of major cell surface proteins is blocked in yeast secretory mutants (1983) (119)
- Tlg2p, a Yeast Syntaxin Homolog That Resides on the Golgi and Endocytic Structures* (1998) (116)
- Yeast secretory mutants that block the formation of active cell surface enzymes (1984) (115)
- Sec8p and Sec15p are components of a plasma membrane-associated 19.5S particle that may function downstream of Sec4p to control exocytosis (1992) (112)
- The Secretory Process and Yeast Cell-surface Assembly (1982) (110)
- Sec3p is involved in secretion and morphogenesis in Saccharomyces cerevisiae. (1997) (108)
- A mammalian guanine-nucleotide-releasing protein enhances function of yeast secretory protein Sec4 (1993) (107)
- Interactions between Rabs, tethers, SNAREs and their regulators in exocytosis. (2006) (107)
- Pag1p, a novel protein associated with protein kinase Cbk1p, is required for cell morphogenesis and proliferation in Saccharomyces cerevisiae. (2002) (102)
- DSS4-1 is a dominant suppressor of sec4-8 that encodes a nucleotide exchange protein that aids Sec4p function (1993) (100)
- A catalytic coiled coil: structural insights into the activation of the Rab GTPase Sec4p by Sec2p. (2007) (99)
- Binding and hydrolysis of guanine nucleotides by Sec4p, a yeast protein involved in the regulation of vesicular traffic. (1990) (94)
- The yeast lgl family member Sro7p is an effector of the secretory Rab GTPase Sec4p (2006) (93)
- Functional specialization within a vesicle tethering complex (2004) (93)
- Lunapark stabilizes nascent three-way junctions in the endoplasmic reticulum (2014) (90)
- Sec15 protein, an essential component of the exocytotic apparatus, is associated with the plasma membrane and with a soluble 19.5S particle (1991) (83)
- ER network formation requires a balance of the dynamin-like GTPase Sey1p and Lnp1p, a member of the Lunapark family (2012) (82)
- The tail of a yeast class V myosin, myo2p, functions as a localization domain. (1999) (82)
- Identification of a Sec4p GTPase-activating Protein (GAP) as a Novel Member of a Rab GAP Family* (1998) (81)
- Sec2 protein contains a coiled-coil domain essential for vesicular transport and a dispensable carboxy terminal domain (1990) (77)
- The Neurospora crassa exocyst complex tethers Spitzenkörper vesicles to the apical plasma membrane during polarized growth (2014) (77)
- The rab exchange factor Sec2p reversibly associates with the exocyst. (2006) (76)
- Ptc1p regulates cortical ER inheritance via Slt2p (2006) (73)
- Yeast rab GTPase-activating protein Gyp1p localizes to the Golgi apparatus and is a negative regulator of Ypt1p. (2001) (72)
- A mammalian inhibitory GDP/GTP exchange protein (GDP dissociation inhibitor) for smg p25A is active on the yeast SEC4 protein (1991) (70)
- Regulation of membrane traffic by Rab GEF and GAP cascades (2016) (64)
- 23 Genes, 23 years later (2004) (61)
- Promiscuity in Rab-SNARE interactions. (1999) (61)
- Aux1p/Swa2p is required for cortical endoplasmic reticulum inheritance in Saccharomyces cerevisiae. (2001) (60)
- Ice2p is important for the distribution and structure of the cortical ER network in Saccharomyces cerevisiae (2005) (57)
- The polarity-establishment component Bem1p interacts with the exocyst complex through the Sec15p subunit (2006) (54)
- Guidebook to the secretory pathway (1994) (54)
- The Role of the Cooh Terminus of Sec2p in the Transport of Post-Golgi Vesicles (2000) (54)
- Fractionation of yeast organelles. (1989) (53)
- The exocyst meets the translocon: a regulatory circuit for secretion and protein synthesis? (2004) (47)
- Synthetic interactions of the post-Golgi sec mutations of Saccharomyces cerevisiae. (2000) (47)
- Dominant negative alleles of SEC10 reveal distinct domains involved in secretion and morphogenesis in yeast. (1998) (47)
- Identification and characterization of homologues of the Exocyst component Sec10p (1997) (44)
- Interactions of Nucleotide Release Factor Dss4p with Sec4p in the Post-Golgi Secretory Pathway of Yeast* (1997) (43)
- Development of cell polarity in budding yeast. (1995) (42)
- The synaptobrevin homologue Snc2p recruits the exocyst to secretory vesicles by binding to Sec6p (2013) (42)
- A snc1 endocytosis mutant: phenotypic analysis and suppression by overproduction of dihydrosphingosine phosphate lyase. (2000) (41)
- Interaction of Sec4 with GDI proteins from bovine brain, Drosophila melanogaster and Saccharomyces cerevisiae (1993) (41)
- Osh4p is needed to reduce the level of phosphatidylinositol-4-phosphate on secretory vesicles as they mature (2014) (39)
- Structure of a C-terminal fragment of its Vps53 subunit suggests similarity of Golgi-associated retrograde protein (GARP) complex to a family of tethering complexes (2010) (39)
- The Rab GTPase YPT‐1 associates with Golgi cisternae and Spitzenkörper microvesicles in Neurospora crassa (2015) (39)
- An internal domain of Exo70p is required for actin-independent localization and mediates assembly of specific exocyst components. (2009) (39)
- ER-phagy requires Lnp1, a protein that stabilizes rearrangements of the ER network (2018) (38)
- Establishing a Role for the GTPase Ypt1p at the Late Golgi (2010) (37)
- SEC6 encodes an 85 kDa soluble protein required for exocytosis in yeast (1992) (34)
- Phosphorylation of the Rab exchange factor Sec2p directs a switch in regulatory binding partners (2013) (34)
- Myo2p, a class V myosin in budding yeast, associates with a large ribonucleic acid-protein complex that contains mRNAs and subunits of the RNA-processing body. (2008) (32)
- Bem1p contributes to secretory pathway polarization through a direct interaction with Exo70p (2014) (32)
- Nuclear pore complex integrity requires Lnp1, a regulator of cortical endoplasmic reticulum (2015) (32)
- The organization, structure, and inheritance of the ER in higher and lower eukaryotes. (2005) (31)
- Ypt32p regulates the translocation of Chs3p from an internal pool to the plasma membrane. (2006) (27)
- Purification and characterization of yeast exocyst complex. (2001) (26)
- Vps13 is required for the packaging of the ER into autophagosomes during ER-phagy (2020) (23)
- Activation of the Mitogen-activated Protein Kinase, Slt2p, at Bud Tips Blocks a Late Stage of Endoplasmic Reticulum Inheritance in Saccharomyces cerevisiae (2010) (19)
- No exchange without receipt (1994) (17)
- The cycle of SEC4 function in vesicular transport. (2007) (17)
- Two subunits of the exocyst, Sec3p and Exo70p, can function exclusively on the plasma membrane (2018) (15)
- Different polarisome components play distinct roles in Slt2p-regulated cortical ER inheritance in Saccharomyces cerevisiae (2013) (15)
- Membrane fusion: Changing partners (2000) (15)
- The synaptobrevin homologue Snc 2 p recruits the exocyst to secretory vesicles by binding to Sec 6 p (15)
- Control of exocytosis in yeast. (1995) (14)
- Yeast secretory mutants: isolation and characterization. (1983) (13)
- [64] Yeast secretory mutants: Isolation and characterization (1983) (13)
- Rewiring a Rab regulatory network reveals a possible inhibitory role for the vesicle tether, Uso1 (2017) (12)
- Distinct and specific GAP activities in rat pancreas on the yeast GTP‐binding proteins Ypt1 and Sec4 (1992) (12)
- Purification and properties of a GTPase-activating protein for yeast Rab GTPases. (2001) (12)
- ER-phagy requires the assembly of actin at sites of contact between the cortical ER and endocytic pits (2022) (11)
- Regulation of vesicular traffic by a GTP-binding protein on the cytoplasmic surface of secretory vesicles in yeast. (1988) (11)
- Membrane traffic. (2010) (11)
- [26] Expression, purification, and assays of Gdilp from recombinant Escherichia coli (1995) (10)
- Intracellular transport mutants of yeast (1985) (10)
- Three Yips for Rab recruitment (2003) (9)
- The casein kinases Yck1p and Yck2p act in the secretory pathway, in part, by regulating the Rab exchange factor Sec2p (2016) (9)
- Analysis of SEC9 Suppression Reveals a Relationship of SNARE Function to Cell Physiology (2009) (9)
- Supplemental Data A Catalytic Coiled Coil : Structural Insights into the Activation of the Rab GTPase Sec 4 p by Sec 2 p (2007) (8)
- Purification of Sec4 protein from Saccharomyces cerevisiae and Escherichia coli. (1992) (5)
- Vesicular transport. No exchange without receipt. (1994) (4)
- Bem 1 p contributes to secretory pathway polarization through a direct interaction with Exo 70 p (2014) (4)
- GIV/Girdin and Exo70 Collaboratively Regulate the Mammalian Polarized Exocytic Machinery (2020) (3)
- Purification Protein complexes in transport vesicle targeting (2000) (3)
- Identification and verification of Sro7p as an effector of the Sec4p Rab GTPase. (2008) (3)
- Ptc 1 p regulates cortical ER inheritance via Slt 2 p (2013) (3)
- A Rab Effector Called the Exocyst and Related Vesicle Tether Complexes (2014) (3)
- Expression, purification, and assays of Gdi1p from recombinant Escherichia coli. (1995) (3)
- Double NPY motifs at the N-terminus of the yeast t-SNARE Sso2 synergistically bind Sec3 to promote membrane fusion (2022) (2)
- Genetic Analysis of Cytoskeletal Protein Function in Yeast (1984) (1)
- A pathway of a hundred genes starts with a single mutant: Isolation of sec1-1 (2014) (1)
- Purification of GDP dissociation stimulator Dss4 from recombinant bacteria. (1995) (1)
- Assaying the interaction of the Rab guanine nucleotide exchange protein Sec2 with the upstream Rab, a downstream effector, and a phosphoinositide. (2015) (1)
- Genes , 23 Years Later Commentary (2006) (0)
- Autophagy of the ER Requires Actin Assembly Driven by the Interaction of ER with Endocytic Pits (2022) (0)
- S7-Targeting, translocation and secretion (2007) (0)
- Hydrolysis of GTP by Sec4 protein plays an important role in vesicular transport and is stimulated by a GTPase-activating protein in Saccharomyces cerevisiae (1992) (0)
- GIV/Girdin and Exo70 Constitute the Core of the Mammalian Polarized Exocytic Machinery (2019) (0)
- Small GTPases and Vesicle Trafficking: Sec4p and its Interaction with Up- and Downstream Elements (1993) (0)
- Crystal Structure of the Exo84p C-terminal Domains (2005) (0)
- Actin assembly at sites of contact between the cortical ER and endocytic pits promotes ER autophagy (2022) (0)
- Table of Contents (1989) (0)
- SNAREs Are Dominant Inhibitors of Membrane Fusion (2000) (0)
- Testing the Phenotypic Effects of a Rab Chimera that Resolves Exchange Factor Specificity from Effector Specificity. (2021) (0)
- The Nucleotide Cycle of Sec4 is Important for Its Function in Vesicular Transport (1993) (0)
- 23 Genes, 23 Years Later Commentary (2004) (0)
- Exploring the consequences of redirecting an exocytic Rab onto endocytic vesicles (2023) (0)
- Microsoft Word-Cdc42/Exo-text(version2) (2001) (0)
- Double NPY motifs at the N-terminus of Sso2 synergistically bind Sec3 to promote membrane fusion (2022) (0)
- Exploring the consequences of redirecting an exocytic Rab onto endocytic vesicles. (2023) (0)
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