Peter Nowell
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American cancer researcher
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Philosophy
Peter Nowell's Degrees
- Doctorate Medicine University of Pennsylvania
Why Is Peter Nowell Influential?
(Suggest an Edit or Addition)According to Wikipedia, Peter Carey Nowell was a cancer researcher and co-discoverer of the Philadelphia chromosome. At the time of his death, he was the Gaylord P. and Mary Louise Harnwell Emeritus Professor of Pathology and Laboratory Medicine at the University of Pennsylvania.
Peter Nowell's Published Works
Published Works
- The clonal evolution of tumor cell populations. (1976) (6248)
- Chromosome preparations of leukocytes cultured from human peripheral blood. (1960) (4064)
- A minute chromosome in human chronic granulocytic leukemia (1960) (2544)
- Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation. (1984) (1793)
- Phytohemagglutinin: an initiator of mitosis in cultures of normal human leukocytes. (1960) (1360)
- Chromosome studies on normal and leukemic human leukocytes. (1960) (1060)
- Mechanisms of tumor progression. (1986) (712)
- Molecular cloning of the chromosomal breakpoint of B-cell lymphomas and leukemias with the t(11;14) chromosome translocation. (1984) (687)
- Association of CYP3A4 genotype with treatment-related leukemia. (1998) (345)
- The chromosome constitution of a human phenotypic intersex. (1959) (332)
- Molecular basis of human B cell neoplasia. (1985) (331)
- Dexamethasone inhibition of interleukin 1 beta production by human monocytes. Posttranscriptional mechanisms. (1988) (319)
- Genes on chromosomes 4, 9, and 19 involved in 11q23 abnormalities in acute leukemia share sequence homology and/or common motifs. (1993) (310)
- Chromosome studies in human leukemia. II. Chronic granulocytic leukemia. (1961) (310)
- Transcriptional activation of the translocated c-myc oncogene in burkitt lymphoma. (1983) (290)
- Characteristics of cultured human melanocytes isolated from different stages of tumor progression. (1985) (283)
- Sequential expression of protooncogenes during lectin-stimulated mitogenesis of normal human lymphocytes. (1986) (277)
- Cloning of the ALL-1 fusion partner, the AF-6 gene, involved in acute myeloid leukemias with the t(6;11) chromosome translocation. (1993) (271)
- Expression of the neu gene-encoded protein (P185neu) in human non-small cell carcinomas of the lung. (1990) (257)
- A 14;18 and an 8;14 chromosome translocation in a cell line derived from an acute B-cell leukemia. (1984) (239)
- Activation of Jak/STAT proteins involved in signal transduction pathway mediated by receptor for interleukin 2 in malignant T lymphocytes derived from cutaneous anaplastic large T-cell lymphoma and Sezary syndrome. (1996) (238)
- Cytogenetics of human malignant melanoma and premalignant lesions. (1984) (225)
- The immunosuppressive macrolide RAD inhibits growth of human Epstein-Barr virus-transformed B lymphocytes in vitro and in vivo: A potential approach to prevention and treatment of posttransplant lymphoproliferative disorders. (2000) (224)
- QUANTITATIVE STUDIES ON THE MIXED LYMPHOCYTE INTERACTION IN RATS (1967) (218)
- Involvement of the TCL5 gene on human chromosome 1 in T-cell leukemia and melanoma. (1989) (217)
- Receptor protein-tyrosine phosphatase gamma is a candidate tumor suppressor gene at human chromosome region 3p21. (1991) (212)
- Expression of the receptor for epidermal growth factor correlates with increased dosage of chromosome 7 in malignant melanoma (1985) (209)
- Regulation of bcl-2 proto-oncogene expression during normal human lymphocyte proliferation. (1987) (207)
- Growth and continued function of rat marrow cells in x-radiated mice. (1956) (200)
- Cloning of ALL-1, the locus involved in leukemias with the t(4;11)(q21;q23), t(9;11)(p22;q23), and t(11;19)(q23;p13) chromosome translocations. (1991) (189)
- Karyotypic evolution in human malignant melanoma. (1986) (184)
- Deregulation of c-myc by translocation of the alpha-locus of the T-cell receptor in T-cell leukemias. (1986) (183)
- Growth factor requirements of childhood acute leukemia: establishment of GM-CSF-dependent cell lines (1987) (178)
- Inhibition of human leukocyte mitosis by prednisolone in vitro. (1961) (177)
- Oncogenic potential of bcl-2 demonstrated by gene transfer (1988) (176)
- Discovery of the Philadelphia chromosome: a personal perspective. (2007) (172)
- QUANTITATIVE STUDIES ON THE MIXED LYMPHOCYTE INTERACTION IN RATS (1970) (167)
- Therapy-related myelodysplastic syndrome and acute myeloid leukemia in children: correlation between chromosomal abnormalities and prior therapy. (1991) (165)
- Heterogeneity of chromosome 22 breakpoint in Philadelphia-positive (Ph+) acute lymphocytic leukemia. (1986) (158)
- Translocation of an immunoglobulin kappa locus to a region 3' of an unrearranged c-myc oncogene enhances c-myc transcription. (1983) (156)
- Effect of cyclosporin A and dexamethasone on interleukin 2 receptor gene expression. (1986) (155)
- BCL2-mediated tumorigenicity of a human T-lymphoid cell line: synergy with MYC and inhibition by BCL2 antisense. (1990) (152)
- QUANTITATIVE STUDIES ON THE MIXED LYMPHOCYTE INTERACTION IN RATS (1971) (151)
- Mantle cell lymphoma cells express predominantly cyclin D1a isoform and are highly sensitive to selective inhibition of CDK4 kinase activity. (2006) (151)
- Primary melanoma cells of the vertical growth phase: similarities to metastatic cells. (1985) (150)
- Tumor progression: a brief historical perspective. (2002) (149)
- Translocation of immunoglobulin VH genes in Burkitt lymphoma. (1982) (149)
- Molecular anatomy of chromosome 7q deletions in myeloid neoplasms: evidence for multiple critical loci. (1998) (147)
- Association of amplified oncogene c-myc with an abnormally banded chromosome 8 in a human leukaemia cell line (1983) (145)
- QUANTITATIVE STUDIES ON THE MIXED LYMPHOCYTE INTERACTION IN RATS (1968) (142)
- Chromosomes of "minimal deviation" hepatomas and some other transplantable rat tumors. (1967) (141)
- Low NAD(P)H:quinone oxidoreductase activity is associated with increased risk of leukemia with MLL translocations in infants and children. (2002) (139)
- Differential effects of Bcl-2 on T and B cells in transgenic mice. (1992) (135)
- Regulation of c-myc mRNA levels in normal human lymphocytes by modulators of cell proliferation. (1985) (132)
- Transcriptional activation of an unrearranged and untranslocated c-myc oncogene by translocation of a C lambda locus in Burkitt. (1983) (131)
- Activation of MYC in a masked t(8;17) translocation results in an aggressive B-cell leukemia. (1989) (127)
- MITOTIC INHIBITION AND CHROMOSOME DAMAGE BY MITOMYCIN IN HUMAN LEUKOCYTE CULTURES. (1964) (125)
- Location of gene for beta subunit of human T-cell receptor at band 7q35, a region prone to rearrangements in T cells. (1985) (123)
- The (4;11)(q21;q23) chromosome translocations in acute leukemias involve the VDJ recombinase. (1992) (121)
- Locus of the alpha-chain of the T-cell receptor is split by chromosome translocation in T-cell leukemias. (1985) (120)
- Evolution of B-cell malignancy: pre-B-cell leukemia resulting from MYC activation in a B-cell neoplasm with a rearranged BCL2 gene. (1988) (119)
- Chromosome studies in preleukemic states. IV. Myeloproliferative versus cytopenic disorders (1978) (119)
- Differentiation of human leukemic leukocytes in tissue culture. (1960) (114)
- Transforming Growth Factor β Production and Responsiveness in Normal Human Melanocytes and Melanoma Cells (1994) (114)
- Analysis of the androgen response of 23 patients with agnogenic myeloid metaplasia: The value of chromosomal studies in predicting response and survival (1982) (108)
- Cytogenetic Findings and Survival in B-cell Chronic Lymphocytic Leukemia. Second IWCCLL Compilation of Data on 662 Patients. (1991) (107)
- A human c-erbA oncogene homologue is closely proximal to the chromosome 17 breakpoint in acute promyelocytic leukemia. (1984) (105)
- Possible involvement of the chromosome region 10q24----q26 in early stages of melanocytic neoplasia. (1988) (104)
- Pre-B-cell leukemia with a t(8; 14) and a t(14; 18) translocation is preceded by follicular lymphoma. (1988) (104)
- Detection of leukemia-associated MLL-GAS7 translocation early during chemotherapy with DNA topoisomerase II inhibitors. (2000) (104)
- Cytogenetics of preleukemia. (1982) (103)
- Molecular analysis of a t(7;14)(g35;g32) chromosome translocation in a T cell leukemia of a patient with ataxia telangiectasia (1988) (102)
- DNA Contents of Chromosome Ph1 and Chromosome 21 in Human Chronic Granulocytic Leukemia (1964) (102)
- Molecular analysis of a t(14;14) translocation in leukemic T-cells of an ataxia telangiectasia patient. (1989) (101)
- Proliferation, differentiation, and cytogenetics of chronic leukemic B lymphocytes cultured with mitomycin-treated normal cells (1981) (100)
- The chromosome 14 breakpoint in neoplastic B cells with the t(11;14) translocation involves the immunoglobulin heavy chain locus. (1984) (95)
- Hepatosplenic and Subcutaneous Panniculitis-Like γ/δ T Cell Lymphomas Are Derived from Different Vδ Subsets of γ/δ T Lymphocytes (2000) (94)
- Near-precise interchromosomal recombination and functional DNA topoisomerase II cleavage sites at MLL and AF-4 genomic breakpoints in treatment-related acute lymphoblastic leukemia with t(4;11) translocation (2001) (89)
- Chronic Lymphocytic Leukemia B Cells Are Resistant to the Apoptotic Effects of Transforming Growth Factor-β (1997) (86)
- Radiation carcinogenesis: the sequence of events. (1965) (84)
- Long‐term integration and neuronal differentiation of human embryonal carcinoma cells (NT era‐2) transplanted into the caudoputamen of nude mice (1996) (83)
- Diagnostic and prognostic significance of Sézary cells in peripheral blood smears from patients with cutaneous T cell lymphoma. (1985) (80)
- Treatment with 13-cis-retinoic acid in transfusion-dependent patients with myelodysplastic syndrome and decreased toxicity with addition of alpha-tocopherol. (1990) (78)
- The most common chromosome change in 86 chronic B cell or T cell tumors: a 14q32 translocation. (1986) (78)
- Evidence for the existence of multipotential lympho‐hematopoietic stem cells in the adult rat (1970) (74)
- Physical mapping of the minimal region of loss in 5q- chromosome. (1995) (73)
- Growth factor requirements of childhood acute T-lymphoblastic leukemia: correlation between presence of chromosomal abnormalities and ability to grow permanently in vitro. (1991) (72)
- Sex chromosome polymorphism and the normal karyotype in three strains of the laboratory rat (1963) (72)
- Panhandle PCR strategy to amplify MLL genomic breakpoints in treatment-related leukemias. (1997) (72)
- Chromosome studies in human leukemia. IV. Myeloproliferative syndrome and other atypical myeloid disorders. (1962) (71)
- Reduced surface expression of transforming growth factor beta receptor type II in mitogen-activated T cells from Sézary patients. (1995) (71)
- BCL2 and JUNB abnormalities in primary cutaneous lymphomas (2004) (70)
- Oligodeoxynucleotide-mediated inhibition of c-myb gene expression in autografted bone marrow: a pilot study. (2002) (69)
- CHROMOSOME CHANGES IN HUMAN LEUKEMIA AND A TENTATIVE ASSESSMENT OF THEIR SIGNIFICANCE (1964) (68)
- Phosphorylation process induced by epidermal growth factor alters the oncogenic and cellular neu (NGL) gene products. (1988) (68)
- Hepatosplenic γδ T-cell lymphoma : Ultrastructural, immunophenotypic, and functional evidence for cytotoxic T lymphocyte differentiation (1997) (67)
- Evidence that TGF-beta can inhibit human T-lymphocyte proliferation through paracrine and autocrine mechanisms. (1993) (67)
- High incidence of human type-C retrovirus (HTLV) in family members of a HTLV-positive Japanese T-cell leukemia patient. (1983) (66)
- Chromosome translocations and B cell neoplasia. (1984) (65)
- The minute chromosome (Phl) in chronic granulocytic leukemia. (1962) (65)
- Amplified C lambda and c-abl genes are on the same marker chromosome in K562 leukemia cells. (1983) (65)
- Clustering of breakpoints on chromosome 10 in acute T-cell leukemias with the t(10;14) chromosome translocation. (1989) (65)
- Chromosome studies in “preleukemia”. III. myelofibrosis (1976) (64)
- Clonal Characteristics of Cutaneous T Cell Lymphomas: Cytogenetic Evidence from Blood, Lymph Nodes, and Skin (1982) (64)
- A phorbol ester (TPA) can replace macrophages in human lymphocyte cultures stimulated with a mitogen but not with an antigen. (1982) (64)
- Marrow chromosome studies in “preleukemia”: Further correlation with clinical course (1971) (63)
- Chromosome studies in preleukemic states: V. Prognostic significance of single versus multiple abnormalities (1986) (63)
- Sézary cell counts in erythrodermic cutaneous T-cell lymphoma: Implications for prognosis and staging (2006) (61)
- Unstable chromosome changes in tuberculin-stimulated leukocyte cultures from irradiated patients. Evidence for immunologically committed, long-lived lymphocytes in human blood. (1965) (60)
- Panhandle PCR for cDNA: a rapid method for isolation of MLL fusion transcripts involving unknown partner genes. (2000) (59)
- Karyotypic stability in chronic B-cell leukemia. (1988) (57)
- Multiplex RT-PCR for the detection of leukemia-associated translocations: validation and application to routine molecular diagnostic practice. (2003) (57)
- Transforming growth factor beta production and responsiveness in normal human melanocytes and melanoma cells. (1994) (54)
- Panhandle and reverse-panhandle PCR enable cloning of der(11) and der(other) genomic breakpoint junctions of MLL translocations and identify complex translocation of MLL, AF-4, and CDK6 (2002) (54)
- Evidence for an interleukin-independent pathway for human lymphocyte activation. (1983) (54)
- Functional role of HLA class I cell-surface molecules in human T-lymphocyte activation and proliferation. (1986) (53)
- Chronic myelogenous leukemia: Laboratory diagnosis and monitoring (2001) (53)
- Hepatosplenic and subcutaneous panniculitis-like gamma/delta T cell lymphomas are derived from different Vdelta subsets of gamma/delta T lymphocytes. (2000) (52)
- Chromosome studies in human leukemia. III. Acute granulocytic leukemia. (1962) (52)
- Chromosome studies of a transplanted and a primary canine venereal sarcoma. (1965) (52)
- Structural alteration in the MYB protooncogene and deletion within the gene encoding alpha-type protein kinase C in human melanoma cell lines. (1988) (52)
- A chromosomal breakage syndrome with profound immunodeficiency (1986) (51)
- A t(1;19) chromosome translocation in three cases of human malignant melanoma. (1986) (50)
- Transcriptional Activation of an Unrearranged and Untranslocated c-myc Oncogene by Translocation of a Clambda Locus in Burkitt Lymphoma Cells (1983) (50)
- Late effects of fast neutrons versus x-rays in mice: nephrosclerosis, tumors, longevity. (1959) (49)
- A clonal CD4-positive T-cell line established from the blood of a patient with Sézary syndrome. (1991) (49)
- Hepatosplenic gamma-delta T-cell lymphoma as a late-onset posttransplant lymphoproliferative disorder in renal transplant recipients. (2000) (49)
- Origins of human cancer revisited (1990) (49)
- IL 2 alone is mitogenic only for Tac-positive lymphocytes in human peripheral blood. (1986) (48)
- Cytogenetics of melanocytic tumors. (1993) (47)
- Detection of myc translocations in lymphoma cells by fluorescence in situ hybridization with yeast artificial chromosomes. (1995) (47)
- The 2p breakpoint of a 2;8 translocation in Burkitt lymphoma interrupts the V kappa locus. (1984) (47)
- Survey of exposure to genotoxic agents in primary myelodysplastic syndrome: correlation with chromosome patterns and data on patients without hematological disease. (1990) (46)
- An altered 11-kilobase transcript in leukemic cell lines with the t(4;11)(q21;q23) chromosome translocation. (1992) (46)
- The role of the accessory cell in mitogen-stimulated human T cell gene expression. (1986) (45)
- Genetic alterations in leukemias and lymphomas: impressive progress and continuing complexity. (1997) (45)
- The mitogenic effect of A23187 in human peripheral lymphocytes. (1977) (45)
- Calcium signaling induces acquisition of dendritic cell characteristics in chronic myelogenous leukemia myeloid progenitor cells. (1999) (44)
- Preleukemia and leukemia with 12p- and 19q+ chromosome alterations following Alkeran therapy. (1985) (44)
- Cytogenetic Evidence for the Clonal Nature of Richter's Syndrome (1981) (44)
- Tumors as clonal proliferation (1978) (44)
- Cytogenetics of chronic T cell leukemia, including two patients with a 14q+ translocation (1978) (44)
- Heterogeneous abnormalities of CCND1 and RB1 in primary cutaneous T-Cell lymphomas suggesting impaired cell cycle control in disease pathogenesis. (2006) (44)
- Regulation of bcl-2 gene expression in lymphoid cell lines containing normal #18 or t(14;18) chromosomes. (1989) (43)
- MLL Genomic Breakpoint Distribution Within the Breakpoint Cluster Region in De Novo Leukemia in Children (1998) (43)
- Sequence analysis of the MYC oncogene involved in the t(8;14)(q24;q11) chromosome translocation in a human leukemia T-cell line indicates that putative regulatory regions are not altered. (1988) (43)
- Alpha-chain locus of the T-cell antigen receptor is involved in the t(10;14) chromosome translocation of T-cell acute lymphocytic leukemia. (1987) (42)
- Differential growth of metastatic tumors in liver and lung; experiments with rabbit V2 carcinoma. (1952) (41)
- Disappearance of cytogenetic abnormalities and clinical remission during therapy with 13-cis-retinoic acid in a patient with myelodysplastic syndrome: inhibition of growth of the patient's malignant monocytoid clone. (1986) (39)
- Prognostic significance of single chromosome abnormalities in preleukemic states. (1989) (39)
- Evidence for early hematopoietic progenitor cell involvement in acute promyelocytic leukemia. (1999) (39)
- Philip Levine award lecture. Chromosome translocations and oncogenes in human lymphoid tumors. (1990) (39)
- Foundations in cancer research. Chromosomes and cancer: the evolution of an idea. (1993) (38)
- Characterization of lymphocyte subpopulations in chronic lymphocytic leukemia (1974) (38)
- Translocation breakpoint mapping: molecular and cytogenetic studies of chromosome 22. (1986) (38)
- Molecular anatomy of a 5q interstitial deletion. (1990) (38)
- Molecular events in tumor development. (1988) (38)
- Molecular cloning and characterization of a cDNA for human granulocyte colony-stimulating factor (G-CSF) from a glioblastoma multiforme cell line and localization of the G-CSF gene to chromosome band 17q21. (1987) (38)
- Suppression of interleukin 2 receptor acquisition by monoclonal antibodies recognizing the 50 KD protein associated with the sheep erythrocyte receptor on human T lymphocytes. (1985) (37)
- Philadelphia Chromosome Symposium: commemoration of the 50th anniversary of the discovery of the Ph chromosome. (2011) (37)
- In situ hybridization and translocation breakpoint mapping (1985) (37)
- CHROMOSOME STUDIES OF VIRUS-INDUCED RABBIT PAPILLOMAS AND DERIVED PRIMARY CARCINOMAS. (1963) (37)
- Functional properties of the 50 kd protein associated with the E-receptor on human T lymphocytes: suppression of IL 2 production by anti-p50 monoclonal antibodies. (1985) (37)
- Isochromosome 17 in Atypical Myeloproliferative and Lymphoproliferative Disorders (1977) (36)
- Preleukemia. Cytogenetic clues in some confusing disorders. (1977) (36)
- Transforming growth factor-beta inhibits human T-cell proliferation through multiple targets. (1992) (36)
- Chromosome abnormalities in myelodysplastic syndromes. (1992) (35)
- Effect of wheat germ agglutinin on the interleukin pathway of human T lymphocyte activation. (1985) (35)
- Spontaneous production of interleukin-1 by human alveolar macrophages. (1983) (34)
- Induction of intestinal carcinoma in the mouse by whole-body fast-neutron irradiation. (1956) (34)
- Molecular genetics of 11q23 chromosome translocations. (1995) (34)
- Chromosomes, genes, and cancer. (1986) (34)
- Etiologic aspects of cold agglutinin disease: evidence for cytogenetically defined clones of lymphoid cells and the demonstration that an anti-Pr cold autoantibody is derived from a chromosomally aberrant B cell clone. (1986) (33)
- Immunophysiological studies of interleukin-2 and canine lymphocytes. (1992) (32)
- Late effects of x-radiation. The influence of dose fractionation on life span, leukemia, and nephrosclerosis incidence in mice. (1960) (31)
- Management of health-care--associated infections in the oncology patient. (2003) (31)
- Chromosomes of "minimal deviation" hepatomas: a further report on diploid tumors. (1969) (31)
- Danazol treatment of myelodysplastic syndromes (1991) (31)
- Chromosomes of primary granulocytic leukemia (chloroleukemia) in the rat. (1963) (30)
- Lineage-specific gene rearrangement/deletion: a nonconservative model. (1989) (30)
- T Cell Variant of Chronic Lymphocytic Leukaemia with Chromosome Abnormality and Defective Response to Mitogens (1976) (30)
- Requirement for extracellular calcium or magnesium in mitogen‐induced activation of human peripheral blood lymphocytes (1988) (30)
- Cytogenetics of acute and chronic myelofibrosis (1978) (30)
- Transition to tetraploidy in 1,25-dihydroxyvitamin D3-resistant HL60 cells is preceded by reduced growth factor dependence and constitutive up-regulation of Sp1 and AP-1 transcription factors. (1996) (29)
- Chromosomal orientation of the lambda light chain locus: Vλ is proximal to Cλ in 22q11 (1985) (29)
- Etiologic aspects of cold agglutinin disease: evidence for cytogenetically defined clones of lymphoid cells and the demonstration that an anti-Pr cold autoantibody is derived from a chromosomally aberrant B cell clone (1986) (29)
- Chromosomal translocation in T-cell leukemia line HUT 78 results in a MYC fusion transcript. (1988) (29)
- Potential role for wild-type p53 in leukemias with MLL gene translocations (1998) (29)
- Chromosome 7 abnormalities in children with Down syndrome and preleukemia. (1991) (29)
- A 2p;11q chromosome translocation in dysmyelopoietic preleukemia. (1985) (28)
- A chromosomal breakage syndrome with profound immunodeficiency. (1986) (28)
- Hepatosplenic gammadelta T-cell lymphoma: ultrastructural, immunophenotypic, and functional evidence for cytotoxic T lymphocyte differentiation. (1997) (28)
- Cancer genetics, cytogenetics—defining the enemy within (1998) (28)
- Proto-oncogene expression in cloned T lymphocytes: mitogens and growth factors induce different patterns of expression. (1987) (28)
- The cytogenetics of human malignant melanoma and premalignant lesions. (1988) (27)
- Cytogenetic evidence for the clonal nature of Richter's syndrome. (1981) (26)
- CHROMOSOME ABNORMALITIES IN LIVER AND MARROW OF MICE IRRADIATED WITH FAST NEUTRONS, GAMMA RAYS, AND X-RAYS: EFFECT OF DOSE RATE. (1965) (26)
- Incidence of neoplasms and other late lesions in mice protected against lethal x-ray doses by spleen homogenate. (1956) (26)
- ACCELERATED INDUCTION OF HEPATOMAS IN FAST NEUTRON‐IRRADIATED MICE INJECTED WITH CARBON TETRACHLORIDE * (1964) (26)
- Sarcoidal tissue reaction in Sézary syndrome. (2000) (26)
- Progesterone augments proliferation induced by epidermal growth factor in a feline mammary adenocarcinoma cell line (1991) (26)
- DISTRIBUTION OF PROLIFERATING DONOR CELLS IN RUNT DISEASE IN RATS (1964) (25)
- Cyclosporin A Directly Inhibits Human B‐Cell Proliferation by More Than a Single Mechanism (1985) (25)
- Anti-HLA class I antibodies inhibit the T cell-independent proliferation of human B lymphocytes. (1987) (25)
- Persistent lymphocytosis with chromosomal evidence of malignancy. (1975) (24)
- Protein kinase C regulates both production and secretion of interleukin 2. (1991) (24)
- Chromosomal Abnormalities and Dyserythropoiesis in the Preleukaemic Phase of Multiple Myeloma (1975) (24)
- Neoplasms of the glandular stomach in mice irradiated with x-rays or fast neutrons. (1958) (24)
- Cytogenetic studies of bone marrow in breast cancer patients after adjuvant chemotherapy (1981) (24)
- Chromosomal and molecular clues to tumor progression. (1989) (24)
- Historical communication: Philadelphia-positive chronic myelogenous leukemia followed for 27 years. (1988) (24)
- CHROMOSOME CHANGES FOLLOWING IRRADIATION IN MAMMALS (1964) (24)
- Panhandle Polymerase Chain Reaction Amplifies MLL Genomic Translocation Breakpoint Involving Unknown Partner Gene (1997) (24)
- Parental-F1 Hybrid Bone Marrow Chimeras: High Incidence of Donor-Type Lymphomas 1 (1970) (24)
- Some Biological Aspects of Lymphocytes Reactive to Strong Histocompatibility Alloantigens (1972) (23)
- t(3;11) translocation in treatment-related acute myeloid leukemia fuses MLL with the GMPS (GUANOSINE 5' MONOPHOSPHATE SYNTHETASE) gene. (2000) (23)
- Chromosome changes in primary tumors. (1965) (23)
- Molecular characterization of a t(11;14)(q23;q32) chromosome translocation in a B-cell lymphoma. (1990) (23)
- XX T cells and XY B cells in two patients with severe combined immune deficiency. (1984) (23)
- A potassium ionophore (Nigericin) inhibits stimulation of human lymphocytes by mitogens (1978) (23)
- Progressive preleukemia with a chromosomally abnormal clone in a kindred with the Estren-Dameshek variant of Fanconi's anemia. (1984) (23)
- Karyotypic differences between primary cultures and cell lines from tumors with the human T-cell leukemia virus. (1984) (23)
- Cytogenetics of chronic B-cell and T-cell leukemia (1980) (23)
- Studies on the life history of lymphocytes. I. The life-span of cells responsive in the mixed lymphocyte interaction. (1971) (23)
- Accessory Cells Provide More Than One Signal for Lectin Mitogen‐Stimulated Proliferation of Human Lymphocytes (1985) (22)
- Malignant and nonmalignant T cell lines from human T cell lymphotropic virus type I-negative patients with Sézary syndrome. (1991) (22)
- Growth factor-dependent differentiation along the myeloid and lymphoid lineages in an immature acute T lymphocytic leukemia. (1990) (22)
- Expression of c-myc proto-oncogene in normal human lymphocytes. Regulation by transcriptional and posttranscriptional mechanisms. (1987) (22)
- Unusually indolent T‐cell prolymphocytic leukemia associated with a complex karyotype: Is this T‐cell chronic lymphocytic leukemia? (2002) (21)
- A novel t(3;8)(q27;q24.1) simultaneously involving both the BCL6 and MYC genes in a diffuse large B-cell lymphoma. (2007) (20)
- Cytogenetics of childhood preleukemia. (1983) (20)
- The distribution and in situ growth pattern of injected rat marrow in x-irradiated mice. (1957) (20)
- Cytogenetic approaches to human cancer genes 1 (1994) (20)
- Cytotoxic T-Lymphocyte Differentiation and Cytogenetic Alterations in γδ Hepatosplenic T-Cell Lymphoma and Posttransplant Lymphoproliferative Disorders (1997) (19)
- Diagnostic and prognostic value of chromosome studies in cancer. (1974) (18)
- Two complex translocations in chronic granulocytic leukemia involving chromosomes 22, 9, and a third chromosome (1975) (18)
- The gene encoding the T4 antigen maps to human chromosome 12. (1986) (18)
- Chromosomal approaches to oncogenes and oncogenesis 1 (1988) (18)
- Lymphocytes and hemic stem cells. (1971) (18)
- REGULATION OF GENE EXPRESSION IN LECTIN‐STIMULATED OR LYMPHOKINE‐STIMULATED T LYMPHOCYTES1 (1988) (18)
- The breakpoint in 22q11 in a case of Ph-positive acute lymphocytic leukemia interrupts the immunoglobulin light chain gene cluster. (1985) (18)
- Trisomy 8 in an allogeneic stem cell transplant recipient representative of a donor‐derived constitutional abnormality (2008) (17)
- Kinetics of mitogen-induced proliferation and differentiation of human peripheral blood B lymphocytes. (1981) (17)
- Monoclonal antibody OKT11A inhibits and recombinant interleukin 2 (IL 2) augments expression of IL 2 receptors at a pretranslational level. (1985) (16)
- Sequential proliferation induced in human peripheral blood lymphocytes by mitogen. II. Suppression by PHA-activated cells. (1977) (16)
- Proliferation, differentiation, and cytogenetics of chronic leukemic B lymphocytes cultured with mitomycin-treated normal cells. (1981) (16)
- E rosette formation at 37°:A property of mitogen-stimulated human peripheral blood lymphocytes (1976) (16)
- Clonal characteristics of cutaneous T cell lymphomas: cytogenetic evidence from blood, lymph nodes, and skin. (1983) (15)
- Altered Response to and Production of TGF-β by B Cells from Autoimmune NZB Mice☆ (1997) (15)
- Kinetics of human lymphocyte proliferation: proportion of cells responsive to phytohemagglutinin and correlation with E rosette formation. (1975) (15)
- Reduced Incidence of Persistent Chromosome Aberrations in Mice Irradiated at Low Dose Rates (1963) (15)
- The clonal nature of neoplasia. (1989) (15)
- Soluble inhibitors of T lymphocyte proliferation: Tools for dissecting pathways of T cell activation (1988) (14)
- Changes in membrane markers and chromosome patterns in chronic T-cell leukemia. (1979) (14)
- Clonal repopulation in reticular tissues of x‐irradiated mice: Effect of dose and of limb‐shielding (1967) (14)
- Progress with chronic myelogenous leukemia: a personal perspective over four decades. (2002) (14)
- Concurrent diagnosis of chronic lymphocytic leukemia and myelodysplastic syndrome. (1997) (13)
- Rapid magnetic purification of rosette-forming lymphocytes. (1979) (13)
- Secondary Ph-positive CML with a minority monosomy 7 clone. (1987) (13)
- Evidence of myeloid differentiation in non-M3 acute myeloid leukemia treated with the retinoid X receptor agonist bexarotene (2007) (13)
- PROGNOSTIC VALUE OF MARROW CHROMOSOME STUDIES IN HUMAN "PRELEUKEMIA". (1965) (13)
- Suppression of the normal mouse c-myc oncogene in human lymphoma cells (1985) (12)
- Hepatomas in Mice: Incidence Increased after Gamma Irradiation at Low Dose Rates (1965) (12)
- Sézary Syndrome Coexisting with B-Cell Chronic Lymphocytic Leukemia: Case Report and Review of the Literature (2007) (12)
- Effect of isologous bone marrow and antibiotics in mice after supralethal x-irradiation (1000 to 1100 r). (1957) (12)
- Ph1-positive acute leukemia with a 17q;21q translocation. (1984) (11)
- LNHIBITION OF BOWEL EPITHELIUM REGENERATION BY GRAFTED HOMOLOGOUS SPLEEN CELLS IN IRRADIATED MICE (1961) (11)
- Trisomy 3 in cold agglutinin disease. (1990) (11)
- Stimulation and inhibition of human T cell subsets by wheat germ agglutinin. (1985) (11)
- The chromosome constitution of a human phenotypic intersex: reconfirmation of a 46-chromosome, XX, apparently non-mosaic "true hermaphrodite". (2009) (11)
- Aberrant responses of human lymphocytic neoplasms to cytokine regulation (1998) (11)
- Panhandle polymerase chain reaction amplifies MLL genomic translocation breakpoint involving unknown partner gene. (1997) (11)
- Sequential proliferation induced in human peripheral blood lymphocytes by mitogen. I. Growth of 1000 lymphocytes in feeder layer cultures. (1977) (10)
- Biological significance of induced human chromosome aberrations. (1969) (10)
- Cytotoxic T-lymphocyte differentiation and cytogenetic alterations in gammadelta hepatosplenic T-cell lymphoma and posttransplant lymphoproliferative disorders. (1997) (10)
- A pilot trial of 13-cis-retinoic acid and alpha-tocopherol with recombinant human erythropoietin in myelodysplastic syndrome patients with progressive or transfusion-dependent anemias. The Central Pennsylvania Oncology Group. (1998) (10)
- The human VpreB gene is located on chromosome 22 near a cluster of $${\text{V}}_{\lambda _1 } $$ gene segments (2004) (10)
- Pathologic changes in old non-irradiated F1 hybrid mice injected with parental-strain spleen cells. (1959) (10)
- The surface ultrastructure of normal and leukemic rat lymphocytes. (1958) (10)
- T and B lymphocytes in chronic lymphocytic leukemia. (1976) (9)
- Karyotypic Progression and Metastasis Formation of Human Tumors (1986) (9)
- Genetic instability and tumor development. (1991) (9)
- FETAL LIVER AND THYMUS: ROLES IN THE ONTOGENESIS OF THE MOUSE IMMUNE SYSTEM (1966) (8)
- The effect of temperature on the growth of virus-induced frog carcinoma. II. The temperature coefficient of growth in vitro. (1953) (8)
- Differential growth of blood-borne metastatic tumors in liver and lung (experiments with rabbit V-2 carcinoma). (1951) (8)
- Molecular genetics of human B cell neoplasia. (1986) (8)
- Duplicated regions of AF-4 intron 4 at t(4;11) translocation breakpoints. (1999) (8)
- Karyotypic and clinical progression in chronic myelogenous leukemia after 30 years. (1992) (8)
- Chromosomal translocations, immunoglobulin genes, and oncogenes in human B-cell tumors. (1985) (8)
- Chromosomal orientation of the lambda light chain locus: V lambda is proximal to C lambda in 22q11. (1985) (8)
- Chronic Lymphocytic Leukemia B Cells Are Resistant to the Apoptotic Effects of Transforming Growth Factor-b (1997) (8)
- The etiology of leukemia: some comments on current studies. (1966) (8)
- How many human cancer genes? (1991) (7)
- Analysis of Clinical, Histopathologic and Immunopathologic Parameters in Erythrodermic Variants of Cutaneous T-Cell Lymphoma with Implications for Staging (1994) (7)
- Chromosomal approaches to the molecular basis of neoplasia. (1986) (7)
- Regulation of gene expression in lectin-stimulated or lymphokine-stimulated T lymphocytes. Effects of cyclosporine. (1988) (7)
- ÆTIOLOGY OF LEUKÆMIA (1960) (7)
- Sequential proliferation induced in human peripheral blood lymphocytes by mitogens. III. Possible mechanisms of suppression by PHA-activated cells. (1978) (6)
- Stimulation of Mitosis in Rat Marrow Cultures by Serum From Infected Rats.∗ (1959) (6)
- Cytogenetics of Neoplasia (1987) (6)
- Chromosome rearrangements in oncogenesis. (1984) (6)
- Two cases of myelodysplastic syndrome with both t(5;20) and 17p+ translocations. (1987) (6)
- Surface ultrastructure of tumor sub-lines differing in adhesiveness. (1960) (5)
- Two adult siblings with thrombocytopenia and a familial 13;14 translocation. (1984) (5)
- Changes in clonal expression during the course of acute leukemia: possible subsets in childhood leukemia. (1982) (5)
- What causes lymphocytic tumors? (1990) (5)
- BONE MARROW TRANSPLANTATION (BMT) IN GAUCHER'S DISEASE (1984) (5)
- Richter's syndrome associated with loss of response to transforming growth factor-beta. (1994) (5)
- CHROMOSOME ABERRATIONS AND IMMUNOLOGICAL MEMORY. (1968) (5)
- Chromosomes and Tumor Progression. (1980) (5)
- Marrow fibrosis associated with a Philadelphia chromosome. (1992) (5)
- Proliferation in vivo of T lymphocytes reactive to histocompatibility alloantigens: a correction (1975) (5)
- Chronic myelomonocytic leukemia in a patient with a familial t(6;16)(q13;q22) translocation. (1987) (5)
- SPECIFIC SUPPRESSION OF WOUND HEALING IN MICE BY GRAFT‐VS-HOST REACTION (1964) (5)
- Clinical Trials and in Vitro Studies of 13 CIS Retinoic Acid in the Myelodysplastic Syndrome (1986) (5)
- In situ hybridization and translocation breakpoint mapping. I. Nonidentical 22q11 breakpoints for the t(9;22) of CML and the t(8;22) of Burkitt lymphoma. (1984) (5)
- Chromosomal and growth factor abnormalities in leukemia. AACR special conference in cancer research. (1991) (5)
- Surface marker analysis and karyotype distinguish acute biphenotypic leukemia from acute myelogenous leukemia expressing terminal deoxynucleotidyl transferase (1991) (5)
- Molecular mechanisms involved in human B and T cell neoplasia. (1986) (4)
- Molecular monitoring of pre-B acute lymphocytic leukemia. (1987) (4)
- Reduced incidence of persistent chromosome aberrations in mice irradiated at low dose rates. (1964) (4)
- Cancer, chromosomes, and genes. (1992) (4)
- Coexistence of myeloid and lymphoid neoplastic subpopulations in chronic myelogenous leukemia. (1981) (4)
- CHAPTER 7 – MECHANISMS OF INTERLEUKIN 2 ACTION: IL-2-INDUCIBLE GENE EXPRESSION IN T LYMPHOCYTES (1988) (4)
- DNA-cytophotometry of lymph node touch imprints in cutaneous T-cell lymphoma. (1988) (4)
- The lymphokine "inhibitor of DNA synthesis" (IDS) suppresses human T lymphocyte proliferation by an interleukin-2-independent mechanism. (1986) (4)
- Ph-negative T cells in a patient with chronic myelogenous leukemia for twenty-eight years. (1989) (4)
- Late effects of x-irradiation in chemically protected mice: alteration of tumor incidence after AET-treatment. (1970) (4)
- Oncogene Activation by Chromosome Translocation (1986) (3)
- Late effects of fractionated x-irradiation in mice. Failure to prevent nonthymic lymphomas by thigh-shielding. (1963) (3)
- Genetic changes in cancer: cause or effect? (1971) (3)
- Chromosomal approaches to hematopoietic oncogenesis (1993) (3)
- Modification of radiation response in mice by heterologous and isologous bone marrow. (1957) (3)
- Oncogenes in normal and neoplastic lymphocytes (1987) (2)
- Interleukins and inhibitors in human lymphocyte regulation. (1984) (2)
- Translocation 11;14 in newly diagnosed chronic myelogenous leukemia. (1995) (2)
- Chromosome alterations in oncogenesis. (1985) (2)
- INCIDENCE OF NEOPLASMS IN MICE PROTECTED AGAINST LETHAL DOSES OF X-RAY BY SPLEEN HOMOGENATE (1956) (2)
- Studies of normal and neoplastic lymphocytes (2002) (2)
- A new polymorphic probe on chromosome 6q: p327A (D6S93). (1991) (2)
- Fifty Years in Cancer Research (2002) (1)
- Hepatosplenic and Subcutaneous Panniculitis-Like g/d T Cell Lymphomas Are Derived from Different Vd Subsets of g/d T Lymphocytes (2000) (1)
- Liver Catalase Activity in Rat Leukemia (1960) (1)
- E rosette formation at 37 degrees C: a property of mitogen-stimulated human peripheral blood lymphocytes. (1976) (1)
- Carcinogenesis by Fast Neutrons Relative to X Rays in Mice: Effect of Uninephrectomy and of CC14, (1964) (1)
- are highly sensitive to selective inhibition of CDK4 kinase activity Mantle cell lymphoma cells express predominantly Cyclin D1a isoform and (2013) (1)
- Deficiency of OKT4+ helper cells in SCID. (1985) (1)
- Regulation of c-myc mRNA levels in normal lymphocytes by modulators of cell proliferation (1985) (1)
- Letter: T cells in chronic lymphocytic leukaemia. (1975) (0)
- Chromosomes, oncogenes, and neoplasia. (1990) (0)
- Oncogene expression in Burkitt's lymphoma. (1984) (0)
- THE EFFECT OF TEMPERATURE ON THE GROWTH OF VIRUS-INDUCED FROG CARCINOMA (1953) (0)
- 966 A SEVERE CHROMOSOMAL BREAK SYNDROME WITH PROFOUND IMMUNODEFICIENCY (1985) (0)
- Philadelphia Chromosome (Ph’) Negative, MLL-Rearranged AML Arising in a Patient Treated with Imatinib for CML. (2005) (0)
- Gene Transfer Investigations of Oncogenes Activated by Chromosomal Translocations in Human Lymphomas and Leukemias: BCL2 and C-MYC (1991) (0)
- Editorial help (2004) (0)
- Clonal repopulation in reticular tissues of x-irradiated mice: effect of dose and of limb-shielding. USNRDL-TR-67-79. (1967) (0)
- (myeloid leukemia/chromosome translocation/p53/in situ hybridization) (2016) (0)
- INCREASED INCIDENCE OF MOUSE HEPATOMAS AND OVARIAN ADENOMAS AFTER LOW-DOSE-RATE GAMMA RADIATION. USNRDL-TR-820. (1965) (0)
- The sequence of events in radiation carcinogenesis: a unifying formulation. USNRDL-TR-930. (1965) (0)
- Editorial help (2004) (0)
- Strong immunostaining of lymphoid cells with an anti bcl 2 antiserum 9718 is a reliable marker of bcl 2 overexpression due to t14 18 (1992) (0)
- Human lymphotoxin mutein lacks hypotensive activity but has higher in vivo antitumor activity than lymphotoxin or tumor necrosis factor (1997) (0)
- 806 TRANSLOCATION BREAKPOINT MAPPING OF 9;22 ALL AND 806 8;22 BURKITT'S LYMPHOMA REVEALS DIFFERING BREAK-POINTS WITHIN 22q11 (1985) (0)
- STUDIES ON THE LIFE HISTORY OF LYMPHOCYTES (1971) (0)
- Mouse hepatomas, increased incidence after low-dose-rate gamma irradiation. Abstr. (1965) (0)
- Late effects of fractionated x-radiation in mice. Failure to prevent non-thymic lymphomas by thigh-shielding. (1962) (0)
- Molecular Anatomy of a 5 q Interstitial Deletion (2003) (0)
- T CELLS IN CHRONIC LYMPHOCYTIC LEUKÆMIA (1975) (0)
- The lymphocyte: a brief summary. (1966) (0)
- Immunoglobulin genes, oncogenes, and human B-cell tumors (1985) (0)
- Regulation of proto-oncogene expression during T lymphocyte activation and proliferation. (1987) (0)
- lymphocytes cultured with mitomycin-treated normal cells Proliferation, differentiation, and cytogenetics of chronic leukemic B (2011) (0)
- Molecular genetics of human B cell neoplasia. (1986) (0)
- Proceedings of the Fifth and Sixth Leucocyte Culture Conferences, J.E. Harris, M.R. Schwarz (Eds.). Academic Press, Vienna (1970 and 1972) (1973) (0)
- Perspectives in Cancer Research Mechanisms of Tumor Progression (2006) (0)
- kindred with the Estren-Dameshek variant of Fanconi's anemia Progressive preleukemia with a chromosomally abnormal clone in a (2011) (0)
- HISTOCHEMICAL DEMONSTRATION OF THE DISTRIBUTION OF INJECTED RAT BONE MARROW GROWING IN X-IRRADIATED MICE (1956) (0)
- autoantibody is derived from a chromosomally aberrant B cell clone cold defined clones of lymphoid cells and the demonstration that an anti-Pr Etiologic aspects of cold agglutinin disease: evidence for cytogenetically (2013) (0)
- Accelerated induction of hepatomas in fast neutron irradiated mice injected with carbon tetrachloride. (1962) (0)
- Review of new bookLeukemia Research, edited by Sven-Aage Killmann and C. N. Muller-Berat. Elmsford, New York, Pergamon Press, Inc. Subscription price $45 per year. (1978) (0)
- Clonal Evolution and Childhood Tumors (1982) (0)
- Diagnostic and Prognostic Significance of S # { 233 } zaryCells in Peripheral Blood Smears From Patients With Cutaneous T Cell Lymphoma (2005) (0)
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