Peter Rutledge
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Chemist
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Chemistry
Peter Rutledge's Degrees
- Bachelors Chemistry University of California, Berkeley
- PhD Chemistry Stanford University
Why Is Peter Rutledge Influential?
(Suggest an Edit or Addition)According to Wikipedia, Peter Jonathan Rutledge is a New Zealand chemist and professor at the School of Chemistry, University of Sydney. His research has focused on drug development for tuberculosis, antibiotics, and metal sensing. He has engaged in some research activity on catalysis.
Peter Rutledge's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Discovery of microbial natural products by activation of silent biosynthetic gene clusters (2015) (638)
- Chemical sensors that incorporate click-derived triazoles. (2011) (313)
- The reaction cycle of isopenicillin N synthase observed by X-ray diffraction (1999) (154)
- Metal complexes as a promising source for new antibiotics† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9sc06460e (2019) (111)
- Lab-in-a-Phone: Smartphone-Based Portable Fluorometer for pH Measurements of Environmental Water (2014) (87)
- Combined "dual" absorption and fluorescence smartphone spectrometers. (2015) (84)
- A click fluorophore sensor that can distinguish Cu(II) and Hg(II) via selective anion-induced demetallation. (2011) (66)
- Correction: Metal complexes as a promising source for new antibiotics (2020) (50)
- Recent Advances in Macrocyclic Fluorescent Probes for Ion Sensing (2017) (45)
- Inhibition Studies of Mycobacterium tuberculosis Salicylate Synthase (MbtI) (2010) (39)
- Alternative oxidation by isopenicillin N synthase observed by X-ray diffraction. (2001) (38)
- Nontoxic Metal-Cyclam Complexes, a New Class of Compounds with Potency against Drug-Resistant Mycobacterium tuberculosis. (2016) (37)
- Reversing the Triazole Topology in a Cyclam‐Triazole‐Dye Ligand Gives a 10‐Fold Brighter Signal Response to Zn2+ in Aqueous Solution (2012) (36)
- Copper, nickel, and zinc cyclam-amino acid and cyclam-peptide complexes may be synthesized with "click" chemistry and are noncytotoxic. (2011) (34)
- Structural studies on the reaction of isopenicillin N synthase with the truncated substrate analogues delta-(L-alpha-aminoadipoyl)-L-cysteinyl-glycine and delta-(L-alpha-aminoadipoyl)-L-cysteinyl-D-alanine. (2005) (34)
- Isopenicillin N synthase mediates thiolate oxidation to sulfenate in a depsipeptide substrate analogue: implications for oxygen binding and a link to nitrile hydratase? (2008) (30)
- Early warning smartphone diagnostics for water security and analysis using real-time pH mapping (2015) (29)
- Crystallographic studies on the reaction of isopenicillin N synthase with an unsaturated substrate analogue. (2003) (27)
- Structural studies on the reaction of isopenicillin N synthase with the substrate analogue delta-(l-alpha-aminoadipoyl)-l-cysteinyl-d-alpha-aminobutyrate. (2003) (26)
- Antitubercular Bis-Substituted Cyclam Derivatives: Structure-Activity Relationships and in Vivo Studies. (2018) (25)
- Interactions of isopenicillin N synthase with cyclopropyl-containing substrate analogues reveal new mechanistic insight. (2007) (25)
- Efficient deprotection of F-BODIPY derivatives: removal of BF2 using Brønsted acids (2015) (25)
- Time-resolved and temperature tuneable measurements of fluorescent intensity using a smartphone fluorimeter. (2017) (24)
- Boronated phosphonium salts containing arylboronic acid, closo-carborane, or nido-carborane: synthesis, X-ray diffraction, in vitro cytotoxicity, and cellular uptake (2010) (23)
- Active-site-mediated elimination of hydrogen fluoride from a fluorinated substrate analogue by isopenicillin N synthase. (2004) (22)
- Easy-To-Synthesize Spirocyclic Compounds Possess Remarkable in Vivo Activity against Mycobacterium tuberculosis. (2018) (20)
- Unexpected Oxidation of a Depsipeptide Substrate Analogue in Crystalline Isopenicillin N Synthase (2006) (20)
- Total synthesis of a novel 2-thiabicyclo[3.2.0]heptan-6-one analogue of penicillin N (2003) (20)
- A Fluorescent “Allosteric Scorpionand” Complex Visualizes a Biological Recognition Event (2013) (20)
- l-Proline-derived ligands to mimic the ‘2-His-1-carboxylate’ triad of the non-haem iron oxidase active site (2012) (19)
- Investigating the oxidation of alkenes by non-heme iron enzyme mimics. (2012) (19)
- A device for the high-pressure oxygenation of protein crystals. (2002) (18)
- Unique binding of a non-natural L,L,L-substrate by isopenicillin N synthase. (2005) (18)
- Structural Studies on the Reaction of Isopenicillin N Synthase with a Sterically Demanding Depsipeptide Substrate Analogue (2009) (17)
- Nanangenines: drimane sesquiterpenoids as the dominant metabolite cohort of a novel Australian fungus, Aspergillus nanangensis (2019) (17)
- A Cyclobutanone Analogue Mimics Penicillin in Binding to Isopenicillin N Synthase (2007) (17)
- Synthesis and structural characterisation of amides from picolinic acid and pyridine-2,6-dicarboxylic acid (2015) (17)
- Neuroprotective peptide-macrocycle conjugates reveal complex structure-activity relationships in their interactions with amyloid β. (2014) (15)
- Cyclobutanone Analogues of β‐Lactam Antibiotics: β‐Lactamase Inhibitors with Untapped Potential? (2017) (15)
- Recently Discovered Secondary Metabolites from Streptomyces Species (2022) (15)
- Synthesis and Evaluation of 1,8‐Disubstituted‐Cyclam/Naphthalimide Conjugates as Probes for Metal Ions (2016) (14)
- Synthesis, carbohydrate- and DNA-binding studies of cationic 2,2':6',2''-terpyridineplatinum(II) complexes containing N- and S-donor boronic acid ligands. (2011) (14)
- Incorporation of Bulky and Cationic Cyclam-Triazole Moieties into Marimastat Can Generate Potent MMP Inhibitory Activity without Inducing Cytotoxicity (2013) (13)
- Mercury binding by ferrocenoyl peptides with sulfur-containing side chains: Electrochemical, spectroscopic and structural studies (2008) (12)
- pH-Responsive quantum dots (RQDs) that combine a fluorescent nanoparticle with a pH-sensitive dye. (2014) (12)
- Design and synthesis of a tetradentate '3-amine-1-carboxylate' ligand to mimic the metal binding environment at the non-heme iron(II) oxidase active site. (2010) (12)
- Molecular Switches for any pH: A Systematic Study of the Versatile Coordination Behaviour of Cyclam Scorpionands. (2018) (11)
- Polyamide-Scorpion Cyclam Lexitropsins Selectively Bind AT-Rich DNA Independently of the Nature of the Coordinated Metal (2011) (11)
- Substrate range and enantioselectivity of epoxidation reactions mediated by the ethene-oxidising Mycobacterium strain NBB4 (2013) (11)
- Synthesis and electrochemical studies of disubstituted ferrocene/dipeptide conjugates with sulfur-containing side chains (2010) (11)
- Bend and twist intramolecular charge transfer and emission for selective metal ion sensing (2015) (10)
- Incorporating a Piperidinyl Group in the Fluorophore Extends the Fluorescence Lifetime of Click-Derived Cyclam-Naphthalimide Conjugates (2014) (10)
- Using Click Chemistry to Tune the Properties and the Fluorescence Response Mechanism of Structurally Similar Probes for Metal Ions (2015) (10)
- Chemical Sensors that Incorporate Click-Derived Triazoles (2011) (8)
- Design and synthesis of an isopenicillin N synthase mimic (2005) (8)
- The crystal structure of isopenicillin N synthase with δ-((L)-α-aminoadipoyl)-(L)-cysteinyl-(D)-methionine reveals thioether coordination to iron. (2011) (8)
- Terminally Truncated Isopenicillin N Synthase Generates a Dithioester Product: Evidence for a Thioaldehyde Intermediate during Catalysis and a New Mode of Reaction for Non‐Heme Iron Oxidases (2017) (8)
- Synthesis, electrochemistry and metal binding properties of monosubstituted ferrocenoyl peptides with thioether-containing sidechains (2011) (8)
- A direct method for the N-tetraalkylation of azamacrocycles (2016) (8)
- cis-Dihydroxylation of alkenes by a non-heme iron enzyme mimic (2008) (7)
- l-Proline derived mimics of the non-haem iron active site catalyse allylic oxidation in acetonitrile solutions (2013) (7)
- Bio-Inspired Nitrile Hydration by Peptidic Ligands Based on L-Cysteine, L-Methionine or L-Penicillamine and Pyridine-2,6-dicarboxylic Acid (2014) (7)
- Crystallographic studies on the binding of selectively deuterated LLD- and LLL-substrate epimers by isopenicillin N synthase. (2010) (7)
- Contrasting fates for 6-alpha-methylpenicillin N upon oxidation by deacetoxycephalosporin C synthase (DAOCS) and deacetoxy/deacetylcephalosporin C synthase (DAOC/DACS). (2001) (6)
- Centralised and portable “network forensics” using smartphone-based diagnostics: Case study — The mapping of tap water pH across Sydney, Australia (2014) (6)
- Isopenicillin N Synthase Binds δ‐(L‐α‐Aminoadipoyl)‐L‐Cysteinyl‐D‐Thia‐allo‐Isoleucine through both Sulfur Atoms (2011) (6)
- The crystal structure of an LLL-configured depsipeptide substrate analogue bound to isopenicillin N synthase. (2010) (6)
- Bengamides display potent activity against drug-resistant Mycobacterium tuberculosis (2019) (6)
- Chemistry in the Time of COVID-19: Reflections on a Very Unusual Semester (2020) (6)
- Absorption and fluorescence spectroscopy on a smartphone (2015) (6)
- Iron complexes of tetramine ligands catalyse allylic hydroxyamination via a nitroso–ene mechanism (2015) (5)
- Conglobatins B–E: cytotoxic analogues of the C2-symmetric macrodiolide conglobatin (2020) (5)
- A smartphone fluorometer – the lab-in-a-phone (2014) (5)
- The crystal structure of isopenicillin N synthase with a dipeptide substrate analogue. (2013) (5)
- CHAPTER 19:Isopenicillin N Synthase (2015) (5)
- Isopenicillin N Synthase: Crystallographic Studies (2021) (4)
- The crystal structure of an isopenicillin N synthase complex with an ethereal substrate analogue reveals water in the oxygen binding site (2013) (4)
- The properties and performance of a pH-responsive functionalised nanoparticle. (2014) (3)
- Tele-substitution Reactions in the Synthesis of a Promising Class of 1,2,4-Triazolo[4,3-a]pyrazine-Based Antimalarials. (2020) (3)
- The Interaction of Isopenicillin N Synthase with Homologated Substrate Analogues δ‐(L‐α‐Aminoadipoyl)‐L‐homocysteinyl‐D‐Xaa Characterised by Protein Crystallography (2013) (3)
- Selective Displacement of a Scorpionand Triazole Ligand from Metallocyclam Complexes Visualised with NMR Spectroscopy (2017) (3)
- Structural studies on the reaction of isopenicillin N synthase with the substrate analogue δ -( L - α -aminoadipoyl)- L -cysteinyl- D - α -aminobutyrate (2003) (3)
- A Treasure Hunt for Chemistry (2011) (2)
- Intelligent smartphone-based portable network diagnostics for water security Case Study realtime pH mapping of tap water (2014) (2)
- Temperature Controlled Portable Smartphone Fluorimeter (2016) (2)
- Total Synthesis of a Novel 2-Thiabicyclo[3.2.0]heptan-6-one Analogue of Penicillin N. (2004) (2)
- Investigating the use of Virtual Reality in teaching chemistry to undergraduate students (2019) (1)
- Tele-Substitution Reactions in the Synthesis of a Promising Class of Antimalarials (2020) (1)
- (2S,4S)-3-Benzoyl-4-benzyl-2-tert-butyl-1,3-oxazolidin-5-one (2012) (1)
- Cover Picture: Inhibition Studies of Mycobacterium tuberculosis Salicylate Synthase (MbtI) (ChemMedChem 7/2010) (2010) (1)
- Nitriles with a Heteroatom Attached to the Cyano Carbon (2005) (1)
- ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (Monocyclic Sulfoxide - Fe COMPLEX) (2000) (0)
- ISOPENICILLIN N SYNTHASE WITH L-D-(A-AMINOADIPOYL)-L-CYSTEINYL-D-ISODEHYDROVALINE (2004) (0)
- Isopenicillin N synthase d-(L-a-aminoadipoyl)-(3R)-methyl-L-cysteine D-a-hydroxyisovaleryl ester complex (Oxygen exposed 5 minutes 20 bar) (2005) (0)
- Isopenicillin N synthase with substrate analogue ACOMP (35minutes oxygen exposure) (2008) (0)
- Isopenicillin N synthase with substrate analogue L,L,D-ACd2Ab (unexposed) (2008) (0)
- EMBEDDING CREATIVE EXERCISES TO PROMOTE LEARNING-CENTRED EXPERIENCES IN CHEMISTRY TUTORIALS (2020) (0)
- Isopenicillin N synthase with AC-O-methyl-D-threonine (2012) (0)
- Isopenicillin N synthase complexed with L-aminoadipoyl-L-cysteinyl-L- hexafluorovaline (2005) (0)
- Fluorescent measurements of Zn2+ on a smartphone (2015) (0)
- Isopenicillin N synthase d-(L-a-aminoadipoyl)-(3R)-methyl-L-cysteine D-a-hydroxyisovaleryl ester complex (anaerobic) (2005) (0)
- Isopenicillin N Synthase Aminoadipoyl-Cysteinyl-Alanine-Fe NO Complex (2005) (0)
- ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (OXYGEN-EXPOSED PRODUCT FROM ANAEROBIC AC-VINYLGLYCINE FE COMPLEX) (2003) (0)
- ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (ANAEROBIC AC-VINYLGLYCINE FE COMPLEX) (2003) (0)
- Symbiosis in chemistry and biology (2006) (0)
- Discovery of antimicrobial compounds from Lendenfeldia, Ircinia and Dysidea sponges using bioassay guided fractionation of marine extracts (2018) (0)
- Crystallographic studies on the reaction cycle of isopenicillin N synthase (2004) (0)
- ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (ACmC Fe COMPLEX) (2000) (0)
- LEARNING ABOUT THE COMPLEXITY OF SCIENCE THROUGH CITIZEN SCIENCE (2020) (0)
- Perphenazine-Macrocycle Conjugates Rapidly Sequester the Aβ42 Monomer and Prevent Formation of Toxic Oligomers and Amyloid. (2022) (0)
- Isopenicillin N synthase with a 2-thiabicycloheptan-6-one product analogue (2007) (0)
- Isopenicillin N Synthase From Aspergillus Nidulans (Anaerobic Ac- methyl-cyclopropylglycine Fe Complex) (2007) (0)
- Isopenicillin N synthase with substrate analogue AsMCOV (oxygen exposed 1min 20bar) (2008) (0)
- ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (OXYGEN EXPOSED PRODUCT FROM ANAEROBIC ACOV FE COMPLEX) (2001) (0)
- Yeppoonic acids A – D: 1,2,4-trisubstituted arene carboxylic acid co-metabolites of conglobatin from an Australian Streptomyces sp. (2021) (0)
- Copper(II) complexes of N-propargyl cyclam ligands reveal a range of coordination modes and colours, and unexpected reactivity. (2020) (0)
- TEACHING CHEMISTRY UNDERGRADUATES TO SHARE THEIR SCIENCE WITH THE PUBLIC (2020) (0)
- Suertides A–C: selective antibacterial cyclic hexapeptides from Amycolatopsis sp. MST-135876v3 (2022) (0)
- Perphenazine-macrocycle conjugates divert Aβ42 towards non-toxic aggregates by monomer sequestration (2020) (0)
- Conglobatins B–E: cytotoxic analogues of the C2-symmetric macrodiolide conglobatin (2020) (0)
- Yeppoonic acids A – D: 1,2,4-trisubstituted arene carboxylic acid co-metabolites of conglobatin from an Australian Streptomyces sp. (2021) (0)
- Isopenicillin N synthase with AC-D-S-methyl-3R-methylcysteine (2011) (0)
- Perphenazine-macrocycle conjugates rapidly sequester the Aβ42 monomer and inhibit amyloid formation (2020) (0)
- tert-Butyldimethylsilanol hemihydrate (2008) (0)
- Isopenicillin N synthase with AC-D-methionine (2012) (0)
- ISOPENICILLIN N SYNTHASE aminoadipoyl-cysteinyl-aminobutyrate-FE-NO COMPLEX (2004) (0)
- Isopenicillin N synthase with substrate analogue AsMCOV (2013) (0)
- ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (ANAEROBIC ACOV FE COMPLEX) (2001) (0)
- Substrate range and enantioselectivity of epoxidation reactions mediated by the ethene-oxidising Mycobacterium strain NBB4 (2012) (0)
- Isopenicillin N synthase with the dipeptide substrate analogue AhC (2013) (0)
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