Peter Ten Ten Dijke
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Molecular Biology
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Biology
Peter Ten Ten Dijke's Degrees
- PhD Molecular Biology University of California, Berkeley
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(Suggest an Edit or Addition)Peter Ten Ten Dijke's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Direct binding of Smad3 and Smad4 to critical TGFβ‐inducible elements in the promoter of human plasminogen activator inhibitor‐type 1 gene (1998) (1861)
- TGF-beta signalling from cell membrane to nucleus through SMAD proteins. (1997) (1323)
- Balancing the activation state of the endothelium via two distinct TGF‐β type I receptors (2002) (1140)
- TGF‐β receptor‐mediated signalling through Smad2, Smad3 and Smad4 (1997) (1056)
- Activin receptor-like kinase 1 modulates transforming growth factor-beta 1 signaling in the regulation of angiogenesis. (2000) (878)
- Identification and Functional Characterization of Distinct Critically Important Bone Morphogenetic Protein-specific Response Elements in the Id1 Promoter* (2002) (857)
- Sclerostin Is an Osteocyte-expressed Negative Regulator of Bone Formation, But Not a Classical BMP Antagonist (2004) (843)
- Identification of type I receptors for osteogenic protein-1 and bone morphogenetic protein-4. (1994) (749)
- Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling. (2003) (713)
- Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling. (1997) (709)
- Identification and Functional Characterization of a Smad Binding Element (SBE) in the JunB Promoter That Acts as a Transforming Growth Factor-β, Activin, and Bone Morphogenetic Protein-inducible Enhancer* (1998) (609)
- Targeting TGF-β Signaling in Cancer. (2017) (608)
- Cloning and characterization of a human type II receptor for bone morphogenetic proteins. (1995) (569)
- Characterization of type I receptors for transforming growth factor-beta and activin. (1994) (564)
- TGF-β in progression of liver disease (2011) (546)
- Abnormal angiogenesis but intact hematopoietic potential in TGF‐β type I receptor‐deficient mice (2001) (543)
- Osteogenic protein-1 binds to activin type II receptors and induces certain activin-like effects (1995) (536)
- BMP-9 signals via ALK1 and inhibits bFGF-induced endothelial cell proliferation and VEGF-stimulated angiogenesis (2007) (499)
- Regulation of cell proliferation by Smad proteins (2002) (453)
- TGF-β-Mediated Epithelial-Mesenchymal Transition and Cancer Metastasis (2019) (449)
- New insights into TGF-beta-Smad signalling. (2004) (448)
- TGF-(beta) type I receptor/ALK-5 and Smad proteins mediate epithelial to mesenchymal transdifferentiation in NMuMG breast epithelial cells. (1999) (441)
- Extracellular control of TGFbeta signalling in vascular development and disease. (2007) (430)
- The L45 loop in type I receptors for TGF‐β family members is a critical determinant in specifying Smad isoform activation (1998) (429)
- Role of Smad Proteins and Transcription Factor Sp1 in p21Waf1/Cip1 Regulation by Transforming Growth Factor-β* (2000) (426)
- Hedgehog creates a gradient of DPP activity in Drosophila wing imaginal discs. (2000) (415)
- Phosphorylation of Ser465 and Ser467 in the C Terminus of Smad2 Mediates Interaction with Smad4 and Is Required for Transforming Growth Factor-β Signaling* (1997) (408)
- Signaling by members of the TGF-beta family in vascular morphogenesis and disease. (2010) (375)
- Differential expression of transforming growth factor-beta 1, -beta 2, and -beta 3 by glioblastoma cells, astrocytes, and microglia. (1992) (370)
- Induction of inhibitory Smad6 and Smad7 mRNA by TGF-beta family members. (1998) (367)
- Smad7 prevents activation of hepatic stellate cells and liver fibrosis in rats. (2003) (363)
- Activin receptor-like kinases: a novel subclass of cell-surface receptors with predicted serine/threonine kinase activity. (1993) (362)
- Induction of sonic hedgehog mediators by transforming growth factor-beta: Smad3-dependent activation of Gli2 and Gli1 expression in vitro and in vivo. (2007) (360)
- FK506 activates BMPR2, rescues endothelial dysfunction, and reverses pulmonary hypertension. (2013) (359)
- The dynamic roles of TGF‐β in cancer (2011) (355)
- Distinct spatial and temporal expression patterns of two type I receptors for bone morphogenetic proteins during mouse embryogenesis. (1995) (344)
- Apoptosis in podocytes induced by TGF-beta and Smad7. (2001) (339)
- SOST/sclerostin, an osteocyte-derived negative regulator of bone formation. (2005) (338)
- Formation of hetero-oligomeric complexes of type I and type II receptors for transforming growth factor-beta. (1994) (325)
- The tumor suppressor Smad4 is required for transforming growth factor beta-induced epithelial to mesenchymal transition and bone metastasis of breast cancer cells. (2006) (323)
- Distinct transforming growth factor-beta (TGF-beta) receptor subsets as determinants of cellular responsiveness to three TGF-beta isoforms. (1990) (315)
- Stimulation of Id1 Expression by Bone Morphogenetic Protein Is Sufficient and Necessary for Bone Morphogenetic Protein–Induced Activation of Endothelial Cells (2002) (314)
- Identification of another member of the transforming growth factor type beta gene family. (1988) (312)
- Specificity, diversity, and regulation in TGF-beta superfamily signaling. (1999) (301)
- Wnt but Not BMP Signaling Is Involved in the Inhibitory Action of Sclerostin on BMP‐Stimulated Bone Formation (2006) (277)
- Endogenous patterns of TGFbeta superfamily signaling during early Xenopus development. (2000) (260)
- Transforming Growth Factor β1 Induces Nuclear Export of Inhibitory Smad7* (1998) (259)
- TGF-beta receptor function in the endothelium. (2005) (258)
- Signaling via hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors. (1996) (257)
- Transforming growth factor-beta signal transduction in angiogenesis and vascular disorders. (2005) (257)
- Matrix metalloproteinase-14 (MT1-MMP)-mediated endoglin shedding inhibits tumor angiogenesis. (2010) (254)
- Deficient Smad7 expression: A putative molecular defect in scleroderma (2002) (253)
- BMP signaling in vascular diseases (2012) (251)
- Differential Inhibition of Smad6 and Smad7 on Bone Morphogenetic Protein- and Activin-mediated Growth Arrest and Apoptosis in B Cells* (1999) (246)
- Transforming growth factor β signal transduction (2002) (239)
- Elucidation of Smad Requirement in Transforming Growth Factor-β Type I Receptor-induced Responses* (2003) (230)
- Signaling of transforming growth factor-beta family members through Smad proteins. (2000) (228)
- TGF-β-Induced Endothelial-Mesenchymal Transition in Fibrotic Diseases (2017) (222)
- Transforming growth factor-beta1 to the bone. (2005) (220)
- Distinct and overlapping patterns of localization of bone morphogenetic protein (BMP) family members and a BMP type II receptor during fracture healing in rats. (1998) (212)
- Osteocyte-derived sclerostin inhibits bone formation: its role in bone morphogenetic protein and Wnt signaling. (2008) (210)
- Signaling interplay between transforming growth factor-β receptor and PI3K/AKT pathways in cancer. (2013) (202)
- SMAD3 represses androgen receptor-mediated transcription. (2001) (201)
- Promoting bone morphogenetic protein signaling through negative regulation of inhibitory Smads (2001) (200)
- Endoglin forms a heteromeric complex with the signaling receptors for transforming growth factor-beta. (1994) (200)
- Oral administration of GW788388, an inhibitor of TGF-beta type I and II receptor kinases, decreases renal fibrosis. (2008) (194)
- Animal models of chronic liver diseases. (2013) (188)
- TRAF4 promotes TGF-β receptor signaling and drives breast cancer metastasis. (2013) (181)
- Genetic and pharmacological targeting of activin receptor-like kinase 1 impairs tumor growth and angiogenesis (2010) (181)
- Lack of Primary Cilia Primes Shear-Induced Endothelial-to-Mesenchymal Transition (2011) (180)
- Annexin A1 regulates TGF-β signaling and promotes metastasis formation of basal-like breast cancer cells (2010) (180)
- Bone morphogenetic protein 7 in the development and treatment of bone metastases from breast cancer. (2007) (174)
- Regulation of endothelial cell plasticity by TGF-β (2011) (173)
- Identification and characterization of LTBP-2, a novel latent transforming growth factor-beta-binding protein. (1994) (173)
- Receptors for transforming growth factor-beta. (1994) (171)
- TGF-β Signaling in Control of Cardiovascular Function. (2018) (169)
- Transforming growth factor β signal transduction in hepatic stellate cells via Smad2/3 phosphorylation, a pathway that is abrogated during in vitro progression to myofibroblasts (2001) (169)
- The bone morphogenetic protein pathway is inactivated in the majority of sporadic colorectal cancers. (2008) (165)
- Cartilage‐Derived Morphogenetic Proteins and Osteogenic Protein‐1 Differentially Regulate Osteogenesis (1998) (165)
- Functionality of Endothelial Cells and Pericytes From Human Pluripotent Stem Cells Demonstrated in Cultured Vascular Plexus and Zebrafish Xenografts (2014) (164)
- Distinct Modes of Inhibition by Sclerostin on Bone Morphogenetic Protein and Wnt Signaling Pathways* (2010) (162)
- Efficient TGF-β Induction of the Smad7 Gene Requires Cooperation between AP-1, Sp1, and Smad Proteins on the Mouse Smad7 Promoter* (2000) (162)
- BMP7, a putative regulator of epithelial homeostasis in the human prostate, is a potent inhibitor of prostate cancer bone metastasis in vivo. (2007) (162)
- Transforming growth factor beta-induced endothelial-to-mesenchymal transition: a switch to cardiac fibrosis? (2008) (161)
- Transforming Growth Factor-β (TGF-β)-mediated Connective Tissue Growth Factor (CTGF) Expression in Hepatic Stellate Cells Requires Stat3 Signaling Activation* (2013) (158)
- Localization of Smads, the TGF‐β Family Intracellular Signaling Components During Endochondral Ossification (1999) (157)
- Smad and AML Proteins Synergistically Confer Transforming Growth Factor β1 Responsiveness to Human Germ-line IgA Genes* (2000) (155)
- Bone morphogenetic protein signaling in bone homeostasis. (2015) (154)
- Loss of SMAD4 alters BMP signaling to promote colorectal cancer cell metastasis via activation of Rho and ROCK. (2014) (154)
- ALK2 R206H mutation linked to fibrodysplasia ossificans progressiva confers constitutive activity to the BMP type I receptor and sensitizes mesenchymal cells to BMP‐induced osteoblast differentiation and bone formation (2009) (153)
- Nuclear Factor YY1 Inhibits Transforming Growth Factor β- and Bone Morphogenetic Protein-Induced Cell Differentiation (2003) (150)
- Physical and Functional Interaction of Murine andXenopus Smad7 with Bone Morphogenetic Protein Receptors and Transforming Growth Factor-β Receptors* (1998) (146)
- Expression of TGF-beta isoforms during first trimester human embryogenesis. (1990) (146)
- Smad7 Is an Activin-inducible Inhibitor of Activin-induced Growth Arrest and Apoptosis in Mouse B Cells* (1998) (145)
- VE‐cadherin is a critical endothelial regulator of TGF‐β signalling (2008) (142)
- Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches (2021) (141)
- Negative regulation of TGF-beta receptor/Smad signal transduction. (2007) (141)
- ALK1 Opposes ALK5/Smad3 Signaling and Expression of Extracellular Matrix Components in Human Chondrocytes (2008) (140)
- Exploring anti-TGF-β therapies in cancer and fibrosis (2011) (140)
- Three-dimensional co-cultures of human endothelial cells and embryonic stem cell-derived pericytes inside a microfluidic device. (2013) (139)
- Diffusion of nodal signaling activity in the absence of the feedback inhibitor Lefty2. (2001) (138)
- Transforming growth factor beta signal transduction. (2002) (137)
- Id1 is a critical mediator in TGF‐β–induced transdifferentiation of rat hepatic stellate cells (2006) (137)
- TGFβ Signaling and Cardiovascular Diseases (2012) (136)
- Activation of the TGF-beta/activin-Smad2 pathway during allergic airway inflammation. (2001) (133)
- TMEPAI, a transmembrane TGF-beta-inducible protein, sequesters Smad proteins from active participation in TGF-beta signaling. (2010) (132)
- Endoglin Has a Crucial Role in Blood Cell–Mediated Vascular Repair (2006) (132)
- Growth differentiation factor-9 induces Smad2 activation and inhibin B production in cultured human granulosa-luteal cells. (2003) (128)
- Activation of bone morphogenetic protein/Smad signaling in bronchial epithelial cells during airway inflammation. (2002) (127)
- Expression of Smad proteins in human colorectal cancer (1999) (126)
- Recombinant transforming growth factor type beta 3: biological activities and receptor-binding properties in isolated bone cells (1990) (125)
- Signaling inputs converge on nuclear effectors in TGF-beta signaling. (2000) (124)
- Age-dependent alteration of TGF-β signalling in osteoarthritis (2011) (124)
- Compensatory signalling induced in the yolk sac vasculature by deletion of TGFβ receptors in mice (2007) (124)
- Deficiency for endoglin in tumor vasculature weakens the endothelial barrier to metastatic dissemination (2013) (123)
- Epithelial–mesenchymal-transition-inducing transcription factors: new targets for tackling chemoresistance in cancer? (2018) (120)
- Snail and Slug, key regulators of TGF-β-induced EMT, are sufficient for the induction of single-cell invasion. (2013) (119)
- Increased smad expression and activation are associated with apoptosis in normal and malignant prostate after castration. (1999) (119)
- Transforming Growth Factor-β1 Mutations in Camurati-Engelmann Disease Lead to Increased Signaling by Altering either Activation or Secretion of the Mutant Protein* (2003) (118)
- Autocrine bone morphogenetic protein-9 signals through activin receptor-like kinase-2/Smad1/Smad4 to promote ovarian cancer cell proliferation. (2009) (117)
- Nonsynonymous variants in the SMAD6 gene predispose to congenital cardiovascular malformation (2012) (116)
- Nodal Signaling Uses Activin and Transforming Growth Factor-β Receptor-regulated Smads* (2001) (114)
- Targeting TGFβ signal transduction for cancer therapy (2021) (113)
- Global Analysis of Smad2/3-Dependent TGF-β Signaling in Living Mice Reveals Prominent Tissue-Specific Responses to Injury1 (2005) (113)
- TGF-beta signaling by Smad proteins. (2000) (112)
- A Perspective on the Development of TGF-β Inhibitors for Cancer Treatment (2019) (111)
- Bone morphogenetic protein receptor signal transduction in human disease (2018) (111)
- Identification of a Key Residue Mediating Bone Morphogenetic Protein (BMP)-6 Resistance to Noggin Inhibition Allows for Engineered BMPs with Superior Agonist Activity* (2010) (111)
- TGF-β Signaling in Breast Cancer Cell Invasion and Bone Metastasis (2011) (110)
- TGFβ-induced metabolic reprogramming during epithelial-to-mesenchymal transition in cancer (2019) (110)
- Endoglin Expression on Cancer-Associated Fibroblasts Regulates Invasion and Stimulates Colorectal Cancer Metastasis (2018) (107)
- Xenopus Smad4beta is the co-Smad component of developmentally regulated transcription factor complexes responsible for induction of early mesodermal genes. (1999) (107)
- Transforming growth factor-β signalling controls human breast cancer metastasis in a zebrafish xenograft model (2013) (103)
- KLF2 Suppresses TGF-&bgr; Signaling in Endothelium Through Induction of Smad7 and Inhibition of AP-1 (2007) (102)
- Smad7-induced beta-catenin degradation alters epidermal appendage development. (2006) (101)
- Connective tissue growth factor expression and Smad signaling during mouse heart development and myocardial infarction (2004) (101)
- TGF-&bgr; family co-receptor function and signaling (2018) (100)
- Endothelial‐to‐mesenchymal transition in cardiovascular diseases: Developmental signaling pathways gone awry (2018) (100)
- Transforming growth factor-beta signaling and tumor angiogenesis. (2009) (99)
- Expression and localization of bone morphogenetic proteins (BMPs) and BMP receptors in ossification of the ligamentum flavum. (1997) (98)
- Dominant-Negative ALK2 Allele Associates With Congenital Heart Defects (2009) (98)
- Transforming growth factor-beta1 (TGF-beta)-induced apoptosis of prostate cancer cells involves Smad7-dependent activation of p38 by TGF-beta-activated kinase 1 and mitogen-activated protein kinase kinase 3. (2003) (98)
- Efficient Association of an Amino-terminally Extended Form of Human Latent Transforming Growth Factor- Binding Protein with the Extracellular Matrix (*) (1995) (96)
- On-Target Anti-TGF-β Therapies Are Not Succeeding in Clinical Cancer Treatments: What Are Remaining Challenges? (2020) (95)
- Bone Morphogenetic Proteins in Vascular Homeostasis and Disease. (2018) (94)
- Signaling by ALK5 mediates TGF-β-induced ET-1 expression in endothelial cells: a role for migration and proliferation (2007) (94)
- BMP-9 interferes with liver regeneration and promotes liver fibrosis (2017) (94)
- Inflammation induces endothelial‐to‐mesenchymal transition and promotes vascular calcification through downregulation of BMPR2 (2019) (94)
- Anti-human Activin Receptor-like Kinase 1 (ALK1) Antibody Attenuates Bone Morphogenetic Protein 9 (BMP9)-induced ALK1 Signaling and Interferes with Endothelial Cell Sprouting* (2012) (94)
- Enhanced expression of transforming growth factor-beta s and transforming growth factor-beta type II receptor in the synovial tissues of patients with rheumatoid arthritis. (1994) (93)
- c-Myb Enhances Breast Cancer Invasion and Metastasis through the Wnt/β-Catenin/Axin2 Pathway. (2016) (93)
- Bone morphogenetic protein receptors and activin receptors are highly expressed in ossified ligament tissues of patients with ossification of the posterior longitudinal ligament. (1997) (93)
- Elevated TGFβ–Smad signalling in experimental Pkd1 models and human patients with polycystic kidney disease (2010) (89)
- RNF12 controls embryonic stem cell fate and morphogenesis in zebrafish embryos by targeting Smad7 for degradation. (2012) (87)
- TGF-β-Induced Endothelial to Mesenchymal Transition in Disease and Tissue Engineering (2020) (86)
- Serine/threonine kinase receptors. (1994) (85)
- Intracellular signaling of osteogenic protein‐1 through Smad5 activation (1998) (84)
- Biphasic effects of transforming growth factor β on bone morphogenetic protein–induced osteoblast differentiation (2011) (84)
- Ubiquitin-specific Protease 4 Mitigates Toll-like/Interleukin-1 Receptor Signaling and Regulates Innate Immune Activation* (2012) (83)
- BMP pathways are involved in otic capsule formation and epithelial-mesenchymal signaling in the developing chicken inner ear. (2002) (82)
- A Novel Type I Receptor Serine-Threonine Kinase Predominantly Expressed in the Adult Central Nervous System* (1996) (81)
- A rapid and sensitive bioassay to measure bone morphogenetic protein activity (2007) (79)
- Ionizing radiation shifts the PAI-1/ID-1 balance and activates notch signaling in endothelial cells. (2009) (79)
- BMP type II receptor as a therapeutic target in pulmonary arterial hypertension (2017) (78)
- Smad1 pathway is activated in systemic sclerosis fibroblasts and is targeted by imatinib mesylate. (2008) (78)
- Controlling angiogenesis by two unique TGF-β type I receptor signaling pathways. (2011) (74)
- Deubiquitinase Activity Profiling Identifies UCHL1 as a Candidate Oncoprotein That Promotes TGFβ-Induced Breast Cancer Metastasis (2019) (74)
- Expression of transforming‐growth‐factor (TGF)‐β receptors and Smad proteins in glioblastoma cell lines with distinct responses to TGF‐β1 (1999) (72)
- Fine‐tuning BMP7 signalling in adipogenesis by UBE2O/E2‐230K‐mediated monoubiquitination of SMAD6 (2013) (72)
- New mechanisms of skin innate immunity: ASK1‐mediated keratinocyte differentiation regulates the expression of β‐defensins, LL37, and TLR2 (2005) (72)
- TGF-β Signaling in Endothelial-to-Mesenchymal Transition: The Role of Shear Stress and Primary Cilia (2012) (72)
- Identification of receptors and Smad proteins involved in activin signalling in a human epidermal keratinocyte cell line (1998) (71)
- A Kinome-Wide Small Interfering RNA Screen Identifies Proviral and Antiviral Host Factors in Severe Acute Respiratory Syndrome Coronavirus Replication, Including Double-Stranded RNA-Activated Protein Kinase and Early Secretory Pathway Proteins (2015) (71)
- Molecular analyses of the 15q and 18q SMAD genes in pancreatic cancer (1999) (69)
- Endoglin promotes TGF‐β/Smad1 signaling in scleroderma fibroblasts (2011) (68)
- Combined Inhibition of TGF-β Signaling and the PD-L1 Immune Checkpoint Is Differentially Effective in Tumor Models (2019) (67)
- Tgfβ/Alk5 signaling is required for shear stress induced klf2 expression in embryonic endothelial cells (2011) (67)
- JUNB governs a feed-forward network of TGFβ signaling that aggravates breast cancer invasion (2017) (66)
- Physical and functional interaction of murine and Xenopus Smad7 with bone morphogenetic protein receptors and transforming growth factor-beta receptors. (1998) (66)
- The BMP pathway either enhances or inhibits the Wnt pathway depending on the SMAD4 and p53 status in CRC (2014) (64)
- Breast cancer metastasis suppressor OTUD1 deubiquitinates SMAD7 (2017) (64)
- The rationale for targeting TGF‐β in chronic liver diseases (2016) (63)
- Gene Array Analysis of Bone Morphogenetic Protein Type I Receptor‐Induced Osteoblast Differentiation (2003) (63)
- Aberrant Bmp signaling and notochord delamination in the pathogenesis of esophageal atresia (2007) (63)
- Elevated transforming growth factor β and mitogen-activated protein kinase pathways mediate fibrotic traits of Dupuytren's disease fibroblasts (2011) (62)
- Genomic characterization of the human DNA excision repair gene ERCC-1. (1987) (62)
- TGF-β receptor signaling pathways in angiogenesis; emerging targets for anti-angiogenesis therapy. (2011) (62)
- ENDOGLIN Is Dispensable for Vasculogenesis, but Required for Vascular Endothelial Growth Factor-Induced Angiogenesis (2014) (62)
- A rate equation approach to elucidate the kinetics and robustness of the TGF-beta pathway. (2006) (61)
- TGF-beta and BMP7 interactions in tumour progression and bone metastasis. (2007) (61)
- Two novel type II receptors mediate BMP signalling and are required to establish left-right asymmetry in zebrafish. (2008) (61)
- Ski co‐repressor complexes maintain the basal repressed state of the TGF‐β target gene, SMAD7, via HDAC3 and PRMT5 (2009) (59)
- The therapeutic potential of targeting the endothelial-to-mesenchymal transition (2018) (59)
- Cancer-associated fibroblast-derived Gremlin 1 promotes breast cancer progression (2019) (58)
- An assay for the determination of biologically active bone morphogenetic proteins using cells transfected with an inhibitor of differentiation promoter-luciferase construct. (2006) (57)
- The prognostic role of TGF-β signaling pathway in breast cancer patients. (2013) (57)
- IL-1 beta and IL-6 selectively induce transforming growth factor-beta isoforms in human articular chondrocytes. (1993) (56)
- Anti-Sclerostin Antibody Inhibits Internalization of Sclerostin and Sclerostin-Mediated Antagonism of Wnt/LRP6 Signaling (2013) (56)
- Transforming growth factor beta signal transduction in hepatic stellate cells via Smad2/3 phosphorylation, a pathway that is abrogated during in vitro progression to myofibroblasts. TGFbeta signal transduction during transdifferentiation of hepatic stellate cells. (2001) (55)
- Bone morphogenetic protein 6 and oxidized low-density lipoprotein synergistically recruit osteogenic differentiation in endothelial cells. (2015) (55)
- Phosphorylation of Ser165 in TGF‐β type I receptor modulates TGF‐β1‐induced cellular responses (1996) (55)
- GSK3β inactivation induces apoptosis of leukemia cells by repressing the function of c-Myb (2011) (54)
- Synthetic triterpenoids enhance transforming growth factor beta/Smad signaling. (2003) (52)
- Cancer associated-fibroblast-derived exosomes in cancer progression (2021) (52)
- Transient Disruption of Autocrine TGF-β Signaling Leads to Enhanced Survival and Proliferation Potential in Single Primitive Human Hemopoietic Progenitor Cells1 (2002) (52)
- BMP-7 inhibits TGF-β-induced invasion of breast cancer cells through inhibition of integrin β3 expression (2011) (51)
- Signal transduction via serine/threonine kinase receptors. (1994) (51)
- Induced Pluripotent Stem Cells to Model Human Fibrodysplasia Ossificans Progressiva (2015) (50)
- Immunotherapeutic Potential of TGF-β Inhibition and Oncolytic Viruses. (2020) (49)
- Expression of TGF-beta related Smad proteins in human epithelial skin tumors. (1999) (48)
- Vanilloid receptor-1 regulates neurogenic inflammation in colon and protects mice from colon cancer. (2012) (48)
- The activities of Smad and Gli mediated signalling pathways in high-grade conventional osteosarcoma. (2012) (48)
- Activin Receptor-like Kinase 1 Ligand Trap Reduces Microvascular Density and Improves Chemotherapy Efficiency to Various Solid Tumors (2015) (47)
- LRP8 mediates Wnt/β‐catenin signaling and controls osteoblast differentiation (2012) (47)
- Epigenetic Reprogramming of TGF-β Signaling in Breast Cancer (2019) (47)
- In Brief: Endothelial‐to‐mesenchymal transition (2016) (46)
- Functional antagonism between activin and osteogenic protein‐1 in human embryonal carcinoma cells (1999) (45)
- Smad protein and TGF-beta signaling in vascular smooth muscle cells. (2003) (45)
- The transcriptional co-activator P/CAF potentiates TGF-beta/Smad signaling. (2000) (45)
- SLUG Is Expressed in Endothelial Cells Lacking Primary Cilia to Promote Cellular Calcification (2015) (44)
- Dual exon skipping in myostatin and dystrophin for Duchenne muscular dystrophy (2011) (44)
- Transforming Growth Factor β Signaling in Colorectal Cancer Cells With Microsatellite Instability Despite Biallelic Mutations in TGFBR2. (2015) (44)
- A covalently dimerized recombinant human bone morphogenetic protein-15 variant identifies bone morphogenetic protein receptor type 1B as a key cell surface receptor on ovarian granulosa cells. (2012) (43)
- TGFβ1-induced SMAD2/3 and SMAD1/5 phosphorylation are both ALK5-kinase-dependent in primary chondrocytes and mediated by TAK1 kinase activity (2017) (43)
- Role of soluble endoglin in BMP9 signaling (2019) (43)
- Expression of Transforming Growth Factor-β1, Activin A, and Their Receptors in Thyroid Follicle Cells: Negative Regulation of Thyrocyte Growth and Function1. (1999) (42)
- Fas-associated factor 1 antagonizes Wnt signaling by promoting β-catenin degradation (2011) (42)
- cDNA cloning, expression studies and chromosome mapping of human type I serine/threonine kinase receptor ALK7 (ACVR1C) (2001) (42)
- Inhibition of Activin Signaling Slows Progression of Polycystic Kidney Disease. (2016) (42)
- TGF-β Family Signaling Pathways in Cellular Dormancy. (2019) (42)
- Time-resolved dissection of early phosphoproteome and ensuing proteome changes in response to TGF-β (2014) (42)
- Bone morphogenetic protein type IB receptor is progressively expressed in malignant glioma tumours. (1996) (42)
- MicroRNA-155 functions as a negative regulator of RhoA signaling in TGF-β-induced endothelial to mesenchymal transition. (2012) (42)
- Nerve growth factor mediates activation of the Smad pathway in PC12 cells. (2004) (42)
- TGFβ signaling in liver regeneration. (2012) (41)
- Temporal smad7 transgene induction in mouse epidermis accelerates skin wound healing. (2011) (41)
- Smad6 determines BMP-regulated invasive behaviour of breast cancer cells in a zebrafish xenograft model (2016) (41)
- Endoglin haploinsufficiency reduces radiation-induced fibrosis and telangiectasia formation in mouse kidneys. (2009) (41)
- TGF-β1/ALK5-induced monocyte migration involves PI3K and p38 pathways and is not negatively affected by diabetes mellitus. (2011) (41)
- Reversible ubiquitination regulates the Smad/TGF-beta signalling pathway. (2006) (41)
- SOST expression is restricted to the great arteries during embryonic and neonatal cardiovascular development (2007) (40)
- Spheroid assay to measure TGF-β-induced invasion. (2011) (39)
- Distribution of phosphorylated Smad2 identifies target tissues of TGF beta ligands in mouse development. (2003) (39)
- USP4 inhibits SMAD4 monoubiquitination and promotes activin and BMP signaling (2017) (39)
- TGFβ and EGF signaling orchestrates the AP-1- and p63 transcriptional regulation of breast cancer invasiveness (2020) (39)
- Shear induced collateral artery growth modulated by endoglin but not by ALK1 (2012) (38)
- Phosphorylation of Smad signaling proteins by receptor serine/threonine kinases. (2001) (38)
- Overactive bone morphogenetic protein signaling in heterotopic ossification and Duchenne muscular dystrophy (2012) (38)
- Activin receptor-like kinase 1 as a target for anti-angiogenesis therapy (2013) (37)
- Endoglin for tumor imaging and targeted cancer therapy (2013) (37)
- Genetic depletion and pharmacological targeting of αv integrin in breast cancer cells impairs metastasis in zebrafish and mouse xenograft models (2015) (37)
- Antisense-Oligonucleotide Mediated Exon Skipping in Activin-Receptor-Like Kinase 2: Inhibiting the Receptor That Is Overactive in Fibrodysplasia Ossificans Progressiva (2013) (36)
- In Situ Proximity Ligation Detection of c-Jun/AP-1 Dimers Reveals Increased Levels of c-Jun/Fra1 Complexes in Aggressive Breast Cancer Cell Lines in Vitro and in Vivo* (2010) (36)
- FAF1 phosphorylation by AKT accumulates TGF-β type II receptor and drives breast cancer metastasis (2017) (35)
- Targeting tumour vasculature by inhibiting activin receptor-like kinase (ALK)1 function. (2016) (35)
- c-Met activation leads to the establishment of a TGFβ-receptor regulatory network in bladder cancer progression (2019) (35)
- Bone morphogenetic protein receptors: Structure, function and targeting by selective small molecule kinase inhibitors. (2020) (35)
- Key signaling nodes in mammary gland development and cancer: Smad signal integration in epithelial cell plasticity (2012) (34)
- Invasive Behavior of Human Breast Cancer Cells in Embryonic Zebrafish. (2017) (34)
- Expression of TGFβ-family signalling components in ageing cartilage: age-related loss of TGFβ and BMP receptors. (2016) (34)
- Bone morphogenetic protein signal transduction in bone. (2006) (33)
- Role of glycosylation in TGF-β signaling and epithelial-to-mesenchymal transition in cancer (2020) (32)
- Latent transforming growth factor-beta complex in Chinese hamster ovary cells contains the multifunctional cysteine-rich fibroblast growth factor receptor, also termed E-selectin-ligand or MG-160. (1997) (32)
- Development of a 96-well plate sample preparation method for integrated N- and O-glycomics using porous graphitized carbon liquid chromatography-mass spectrometry. (2020) (32)
- Methylation of Smad6 by protein arginine N‐methyltransferase 1 (2006) (31)
- Bone Morphogenetic Protein 9 Protects against Neonatal Hyperoxia-Induced Impairment of Alveolarization and Pulmonary Inflammation (2017) (29)
- Transforming Growth Factor (TGF-β)-specific Signaling by Chimeric TGF-β Type II Receptor with Intracellular Domain of Activin Type IIB Receptor* (1997) (29)
- Current perspectives on inhibitory SMAD7 in health and disease (2020) (28)
- Characterization of the binding of transforming growth factor-beta 1, -beta 2, and -beta 3 to recombinant beta 1-latency-associated peptide. (1992) (28)
- Autophagy contributes to BMP type 2 receptor degradation and development of pulmonary arterial hypertension (2019) (28)
- Regulation of the TGF-β pathway by deubiquitinases in cancer. (2016) (28)
- Expression of transforming-growth-factor (TGF)-beta receptors and Smad proteins in glioblastoma cell lines with distinct responses to TGF-beta1. (1999) (28)
- TGFβ Activates Mitogen- and Stress-activated Protein Kinase-1 (MSK1) to Attenuate Cell Death* (2010) (27)
- GREM1 is associated with metastasis and predicts poor prognosis in ER-negative breast cancer patients (2019) (26)
- Targeting TGF-β Signaling by Antisense Oligonucleotide-mediated Knockdown of TGF-β Type I Receptor (2014) (26)
- Fas-associated Factor 1 Is a Scaffold Protein That Promotes β-Transducin Repeat-containing Protein (β-TrCP)-mediated β-Catenin Ubiquitination and Degradation* (2012) (26)
- Expression of the inhibitory Smad7 in early mouse development and upregulation during embryonic vasculogenesis (2000) (26)
- Therapeutic targeting of TGF-β in cancer: hacking a master switch of immune suppression. (2021) (26)
- Smad3 Is a Key Nonredundant Mediator of Transforming Growth Factor β Signaling in Nme Mouse Mammary Epithelial Cells (2009) (26)
- Disorganised stroma determined on pre‐treatment breast cancer biopsies is associated with poor response to neoadjuvant chemotherapy: Results from the NEOZOTAC trial (2015) (25)
- Assignment1 of the Smad7 gene (MADH7) to human chromosome 18q21.1 by fluorescence in situ hybridization (1998) (24)
- Mutational Analysis of Sclerostin Shows Importance of the Flexible Loop and the Cystine-Knot for Wnt-Signaling Inhibition (2013) (24)
- Role of endoglin in fibrosis and scleroderma. (2012) (24)
- Novel Ex Vivo Culture Method for the Study of Dupuytren's Disease: Effects of TGFβ Type 1 Receptor Modulation by Antisense Oligonucleotides (2014) (23)
- Delta-Like Ligand 4 Modulates Liver Damage by Down-Regulating Chemokine Expression. (2016) (23)
- A Rat Pituitary Tumor Cell Line (GH) Expresses Type I and Type II Receptors and Other Cell Surface Binding Protein(s) for Transforming Growth Factor- (*) (1995) (23)
- Key role for ubiquitin protein modification in TGFβ signal transduction (2012) (23)
- Fibulin-4 deficiency increases TGF-β signalling in aortic smooth muscle cells due to elevated TGF-β2 levels (2015) (23)
- Immunohistochemical Localization of Osteogenetic Protein (OP-1) and Its Receptors in Rabbit Articular Cartilage (2002) (22)
- Fluid shear stress-induced TGF-β/ALK5 signaling in renal epithelial cells is modulated by MEK1/2 (2017) (22)
- Bone morphogenetic protein 9 as a key regulator of liver progenitor cells in DDC‐induced cholestatic liver injury (2018) (22)
- Fish tales: The use of zebrafish xenograft human cancer cell models. (2017) (21)
- Orthotopic ossification of the spinal ligaments of zucker fatty rats: A possible animal model for ossification of the human posterior longitudinal ligament (1997) (21)
- Endothelium-derived stromal cells contribute to hematopoietic bone marrow niche formation. (2021) (20)
- Characterization of in vivo phosphorylation of activin type II receptor. (1993) (20)
- 5-Aminosalicylic acid inhibits TGF-beta1 signalling in colorectal cancer cells. (2010) (19)
- Development of Macrocycle Kinase Inhibitors for ALK2 Using Fibrodysplasia Ossificans Progressiva‐Derived Endothelial Cells (2019) (19)
- Regulation of endothelial barrier function by TGF‐β type I receptor ALK5: Potential role of contractile mechanisms and heat shock protein 90 (2012) (19)
- Transforming growth factor-beta-mediated mast cell migration depends on mitogen-activated protein kinase activity. (2001) (18)
- Wnt/β-catenin signaling changes C2C12 myoblast proliferation and differentiation by inducing Id3 expression. (2012) (18)
- The high affinity ALK1-ligand BMP9 induces a hypertrophy-like state in chondrocytes that is antagonized by TGFβ1. (2015) (18)
- Expression of transforming growth factor-beta1, activin A, and their receptors in thyroid follicle cells: negative regulation of thyrocyte growth and function. (1999) (17)
- Prevention of progression of pulmonary hypertension by the Nur77 agonist 6-mercaptopurine: role of BMP signalling (2019) (17)
- Wild-type p53 inhibits pro-invasive properties of TGF-β3 in breast cancer, in part through regulation of EPHB2, a new TGF-β target gene (2014) (17)
- Hepatocyte-specific Smad7 deletion accelerates DEN-induced HCC via activation of STAT3 signaling in mice (2017) (16)
- Chromosomal localization of three human genes encoding bone morphogenetic protein receptors (1999) (16)
- Ectopic expression of Smad7 inhibits transforming growth factor-beta responses in vascular smooth muscle cells. (2001) (16)
- Cloning and characterization of p70(S6K beta) defines a novel family of p70 S6 kinases. (1998) (16)
- Differential O- and Glycosphingolipid Glycosylation in Human Pancreatic Adenocarcinoma Cells With Opposite Morphology and Metastatic Behavior (2020) (16)
- New function of the myostatin/activin type I receptor (ALK4) as a mediator of muscle atrophy and muscle regeneration (2016) (16)
- Visualizing TGF-β and BMP signaling in human atherosclerosis: a histological evaluation based on Smad activation. (2012) (15)
- Transforming growth factor beta and wound healing in human cholesteatoma. (2008) (15)
- Smad2 Phosphorylation in Diabetic Kidney Tubule Epithelial Cells Is Associated with Modulation of Several Transforming Growth Factor-β Family Members (2017) (15)
- Bone morphogenetic protein signalling in NGF-stimulated PC12 cells. (2003) (15)
- Tacrolimus-Induced BMP/SMAD Signaling Associates With Metabolic Stress–Activated FOXO1 to Trigger β-Cell Failure (2019) (15)
- A current perspective on applications of macrocyclic‐peptide‐based high‐affinity ligands (2016) (15)
- Clinical Utility Gene Card for: Fibrodysplasia ossificans progressiva (2015) (15)
- Combinatorial Therapeutic Approaches with Nanomaterial-Based Photodynamic Cancer Therapy (2022) (14)
- TMED10 Protein Interferes with Transforming Growth Factor (TGF)-β Signaling by Disrupting TGF-β Receptor Complex Formation* (2017) (14)
- Interrogating TGF-β Function and Regulation in Endothelial Cells. (2016) (13)
- Secreted BMP antagonists and their role in cancer and bone metastases. (2020) (13)
- Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells (2020) (12)
- TGF‐β signaling in liver metastasis (2020) (12)
- A comprehensive enhancer screen identifies TRAM2 as a key and novel mediator of YAP oncogenesis (2021) (12)
- Transforming growth factor type beta 3 maps to human chromosome 14, region q23-q24. (1988) (11)
- TGF-β-Induced Endothelial to Mesenchymal Transition Is Determined by a Balance Between SNAIL and ID Factors (2021) (11)
- Regulatory RNAs controlling vascular (dys)function by affecting TGF-ß family signalling (2015) (11)
- Follistatin‐controlled activin‐HNF4α‐coagulation factor axis in liver progenitor cells determines outcome of acute liver failure (2021) (11)
- E3 Ubiquitin Ligases: Key Regulators of TGFβ Signaling in Cancer Progression (2021) (10)
- Role of TGF-beta in the tumor stroma. (2008) (10)
- Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling (2022) (10)
- Cancer associated-fibroblast-derived exosomes in cancer progression (2021) (10)
- RLP, a novel Ras-like protein, is an immediate-early transforming growth factor-beta (TGF-beta) target gene that negatively regulates transcriptional activity induced by TGF-beta. (2004) (10)
- JNK-Dependent cJun Phosphorylation Mitigates TGFβ- and EGF-Induced Pre-Malignant Breast Cancer Cell Invasion by Suppressing AP-1-Mediated Transcriptional Responses (2019) (9)
- Lack of responsiveness to TGF-beta1 in a thyroid carcinoma cell line with functional type I and type II TGF-beta receptors and Smad proteins, suggests a novel mechanism for TGF-beta insensitivity in carcinoma cells. (1999) (9)
- Reactivation of BMP signaling by suboptimal concentrations of MEK inhibitor and FK506 reduces organ-specific breast cancer metastasis. (2020) (9)
- Towards a cure for Fibrodysplasia ossificans progressiva. (2016) (9)
- Microfluidics meets 3D cancer cell migration. (2022) (9)
- The prognostic role of TGF-β signaling pathway in breast cancer patients. (2013) (8)
- Fibrodysplasia Ossificans Progressiva: What Have We Achieved and Where Are We Now? Follow-up to the 2015 Lorentz Workshop (2021) (8)
- Bone morphogenetic protein receptors. (1996) (8)
- A Signaling Crosstalk between BMP9 and HGF/c-Met Regulates Mouse Adult Liver Progenitor Cell Survival (2020) (8)
- VprBP mitigates TGF-β and Activin signaling by promoting Smurf1-mediated type I receptor degradation (2019) (8)
- 6-mercaptopurine, an agonist of Nur77, reduces progression of pulmonary hypertension by enhancing BMP signalling. (2019) (8)
- Heterozygous disruption of activin receptor-like kinase 1 is associated with increased arterial pressure in mice (2015) (7)
- Transforming growth factor (TGF-beta)-specific signaling by chimeric TGF-beta type II receptor with intracellular domain of activin type IIB receptor. (1997) (7)
- Activin A induces a non-fibrotic phenotype in smooth muscle cells in contrast to TGF-β. (2011) (7)
- Determining TGF-β Receptor Levels in the Cell Membrane. (2016) (7)
- CD161 expression and regulation defines rapidly responding effector CD4+ T cells associated with improved survival in HPV16-associated tumors (2022) (7)
- Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer Cells. (2020) (7)
- ALK1Fc Suppresses the Human Prostate Cancer Growth in in Vitro and in Vivo Preclinical Models (2017) (7)
- USP8 promotes cancer progression and extracellular vesicle‐mediated CD8+ T cell exhaustion by deubiquitinating the TGF‐β receptor TβRII (2022) (6)
- The effects of transforming growth factor beta 3 on the growth of highly enriched hematopoietic progenitor cells derived from normal human bone marrow and peripheral blood. (1991) (6)
- Cripto favors chondrocyte hypertrophy via TGF‐β SMAD1/5 signaling during development of osteoarthritis (2021) (6)
- Disparate phospho-Smad2 levels in advanced type 2 diabetes patients with diabetic nephropathy and early experimental db/db mouse model (2017) (6)
- Generation of Fibrodysplasia ossificans progressiva and control integration free iPSC lines from periodontal ligament fibroblasts. (2019) (5)
- The protein kinase LKB1 promotes self‐renewal and blocks invasiveness in glioblastoma (2021) (5)
- In vivo imaging of TGFβ signalling components using positron emission tomography. (2019) (5)
- Ter94/VCP Is a Novel Component Involved in BMP Signaling (2014) (5)
- Metabolic Reprogramming of Mammary Epithelial Cells during TGF-β-Induced Epithelial-to-Mesenchymal Transition (2021) (5)
- Eccrine sweat glands: expression of transforming growth factor-beta and bone morphogenetic protein type I receptors and their intracellular signalling Smad proteins. (1999) (5)
- TGF-β in progression of liver disease (2011) (4)
- 14-3-3ζ turns TGF-β to the dark side. (2015) (4)
- New function of the myostatin/activin type I receptor (ALK4) as a mediator of muscle atrophy and muscle regeneration. (2017) (4)
- Challenges and Opportunities for Drug Repositioning in Fibrodysplasia Ossificans Progressiva (2021) (4)
- Crystal structures of BMPRII extracellular domain in binary and ternary receptor complexes with BMP10 (2022) (4)
- TGF-β Pathway (2020) (4)
- A Programmable Multifunctional 3D Cancer Cell Invasion Micro Platform. (2022) (4)
- Cercosporamide inhibits bone morphogenetic protein receptor type I kinase activity in zebrafish (2020) (4)
- RNF12 is regulated by AKT phosphorylation and promotes TGF-β driven breast cancer metastasis (2022) (4)
- Combinatorial therapeutic approaches of photodynamic therapy and immune checkpoint blockade for colon cancer treatment (2022) (4)
- TGF-β-mediated Endothelial to Mesenchymal Transition (EndMT) and the Functional Assessment of EndMT Effectors using CRISPR/Cas9 Gene Editing. (2021) (3)
- Integration of transcriptional signals at the tumor cell invasive front (2010) (3)
- Inhibiting Endothelial Cell Function in Normal and Tumor Angiogenesis Using BMP Type I Receptor Macrocyclic Kinase Inhibitors (2021) (3)
- Deregulated bone morphogenetic protein receptor signaling underlies fibrodysplasia ossificans progressiva. (2012) (3)
- Molecular characterization of transforming growth factor type beta 3. (1990) (3)
- OVOL1 inhibits breast cancer cell invasion by enhancing the degradation of TGF-β type I receptor (2022) (3)
- Author Correction: c-Met activation leads to the establishment of a TGFβ-receptor regulatory network in bladder cancer progression (2019) (2)
- A novel pancreatic cancer mini-tumor model to study desmoplasia and MyCAF differentiation (2022) (2)
- BMP type II receptor as a therapeutic target in pulmonary arterial hypertension (2017) (2)
- MnTBAP Reverses Pulmonary Vascular Remodeling and Improves Cardiac Function in Experimentally Induced Pulmonary Arterial Hypertension (2020) (2)
- TGFβ selects for pro‐stemness over pro‐invasive phenotypes during cancer cell epithelial–mesenchymal transition (2022) (2)
- Transforming growth factor-beta signaling via ALK1 and ALK5 regulates distinct functional pathways in vein graft intimal hyperplasia (2019) (2)
- Vascular defects associated with hereditary hemorrhagic telangiectasia revealed in patient-derived isogenic iPSCs in 3D vessels on chip (2022) (2)
- Photodynamic Therapy in Combination with the Hepatitis B Core Virus-like Particles (HBc VLPs) to Prime Anticancer Immunity for Colorectal Cancer Treatment (2022) (2)
- Breast cancer dormancy is associated with a 4NG1 state and not senescence (2021) (2)
- Assessment of functional competence of endothelial cells from human pluripotent stem cells in zebrafish embryos. (2014) (2)
- The polarity protein Par3 coordinates positively self-renewal and negatively invasiveness in glioblastoma (2021) (1)
- Fine-tuning ALK1 linear polyubiquitination to control angiogenesis. (2021) (1)
- Inhibition of the prolyl isomerase Pin1 improves endothelial function and attenuates vascular remodelling in pulmonary hypertension by inhibiting TGF-β signalling (2021) (1)
- BMP-7 inhibits TGF-β-induced invasion of breast cancer cells through inhibition of integrin β3 expression (2011) (1)
- TRAF4 Inhibits Bladder Cancer Progression by Promoting BMP/SMAD Signaling (2020) (1)
- Synthesis and preclinical evaluation of [11C]LR111 and [18F]EW-7197 as PET tracers of the activin-receptor like kinase-5. (2022) (1)
- ALK1 controls hepatic vessel formation, angiodiversity, and angiocrine functions in hereditary hemorrhagic telangiectasia of the liver (2022) (1)
- An Experimental Liver Metastasis Mouse Model Suitable for Short and Long‐Term Intravital Imaging (2021) (1)
- Key signaling nodes in mammary gland development and cancer: Smad signal integration in epithelial cell plasticity (2012) (1)
- Genetic depletion and pharmacological targeting of αv integrin in breast cancer cells impairs metastasis in zebrafish and mouse xenograft models (2015) (1)
- Harnessing epithelial-mesenchymal plasticity to boost cancer immunotherapy (2023) (1)
- Low Transforming Growth Factor-β Pathway Activity in Cervical Adenocarcinomas (2022) (1)
- A comprehensive enhancer screen identifies TRAM2 as a key and novel mediator of YAP oncogenesis (2021) (1)
- Visualizing Dynamic Changes During TGF-β-Induced Epithelial to Mesenchymal Transition. (2022) (1)
- Cancer-associated fibroblast-derived Gremlin 1 promotes breast cancer progression (2019) (1)
- Emerging regulators of BMP bioavailability. (2016) (1)
- Transforming growth factor-β signalling controls human breast cancer metastasis in a zebrafish xenograft model (2013) (1)
- ST3GAL5‐catalyzed gangliosides inhibit TGF‐β‐induced epithelial‐mesenchymal transition via TβRI degradation (2022) (1)
- 18th European Symposium on Radiopharmacy and Radiopharmaceuticals (2016) (1)
- Measurement of constitutive activity of BMP type I receptors. (2010) (0)
- Developing advanced cell culture models to study COVID-19-associated pulmonary fibrosis (2022) (0)
- Correction: Mutational Analysis of Sclerostin Shows Importance of the Flexible Loop and the Cystine-Knot for Wnt-Signaling Inhibition (2014) (0)
- Dissection of N-, O- and glycosphingolipid glycosylation changes in PaTu-S pancreatic adenocarcinoma cells upon TGF-β challenge (2021) (0)
- Inhibition of TGFβ type I receptor activity facilitates liver regeneration upon acute CCl4 intoxication in mice (2015) (0)
- Abstract 19603: Bone Morphogenetic Protein 6 and Oxidized Low-density Lipoprotein Synergistically Recruit Osteogenic Differentiation in Endothelial Cells (2015) (0)
- Breast cancer metastasis suppressor OTUD1 deubiquitinates SMAD7 (2017) (0)
- A Novel Pancreatic Cancer Mini-tumor Model to Study Desmoplasia and Myofibroblastic Cancer-Associated Fibroblast Differentiation (2022) (0)
- GREM1 is associated with metastasis and predicts poor prognosis in ER-negative breast cancer patients (2019) (0)
- RNF12 is regulated by AKT phosphorylation and promotes TGF-β driven breast cancer metastasis (2022) (0)
- TGF-β in aging and disease (2011) (0)
- Editorial: TGF-β and BMP signaling in cancer (2022) (0)
- TGFβ-induced metabolic reprogramming during epithelial-to-mesenchymal transition in cancer (2019) (0)
- Differential optineurin expression controls TGFβ signaling and is a key determinant for metastasis of triple negative breast cancer (2023) (0)
- TGF-β signalling and its role in cancer progression and metastasis (2012) (0)
- Overactive bone morphogenetic protein signaling in heterotopic ossification and Duchenne muscular dystrophy (2012) (0)
- The therapeutic potential of targeting the endothelial-to-mesenchymal transition (2018) (0)
- Age-dependent alteration of TGF-β signalling in osteoarthritis (2011) (0)
- Uncovering the deubiquitinase activity landscape of breast cancer (2020) (0)
- Inhibition of the prolyl isomerase Pin1 improves endothelial function and attenuates vascular remodelling in pulmonary hypertension by inhibiting TGF-β signalling (2021) (0)
- Controlling Smad4 signaling with a Wip (2020) (0)
- LncRNA LITATS1 suppresses TGF-β-induced EMT and cancer cell plasticity by potentiating TβRI degradation. (2023) (0)
- Opposing USP19 splice variants in TGF-β signaling and TGF-β-induced epithelial–mesenchymal transition of breast cancer cells (2023) (0)
- Establishment of Embryonic Zebrafish Xenograft Assays to Investigate TGF-β Family Signaling in Human Breast Cancer Progression. (2022) (0)
- A Programmable Multifunctional 3D Cancer Cell Invasion Micro Platform (Small 20/2022) (2022) (0)
- Combination of photodynamic therapy and stimulator of interferon genes (STING) agonist inhibits colorectal tumor growth and recurrence (2023) (0)
- Surface topography is a context-dependent activator of TGF-β signaling in mesenchymal stem cells (2020) (0)
- TGF-β Signalling in Cancer: Role and Therapeutic Targeting of the Tumour Stroma (2021) (0)
- Enhancing anti-tumor immunity through liposomal oxaliplatin and localized immunotherapy via STING activation. (2023) (0)
- 132 Non-synonymous SMAD6 mutations impaired inhibition of bmp signalling in patients with congenital cardiovascular malformation (2011) (0)
- Dynamic Visualization of TGF-β/SMAD3 Transcriptional Responses in Single Living Cells (2022) (0)
- Erratum to: BMP type II receptor as a therapeutic target in pulmonary arterial hypertension (2017) (0)
- Fluid shear stress-induced TGF-β/ALK5 signaling in renal epithelial cells is modulated by MEK1/2 (2017) (0)
- Imaging the TGFβ type I receptor in pulmonary arterial hypertension (2023) (0)
- Intertumoral Differences Dictate the Outcome of TGF-β Blockade on the Efficacy of Viro-Immunotherapy (2023) (0)
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