Peter W Laird
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Researcher ORCID ID = 0000-0001-9117-3641
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Computer Science
Peter W Laird's Degrees
- PhD Computer Science Stanford University
- Masters Computer Science University of California, Berkeley
- Bachelors Computer Science University of California, Berkeley
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(Suggest an Edit or Addition)Peter W Laird's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Comprehensive molecular portraits of human breast tumors (2012) (7791)
- Integrated Genomic Analyses of Ovarian Carcinoma (2011) (6411)
- Comprehensive molecular characterization of human colon and rectal cancer (2012) (6141)
- Comprehensive genomic characterization defines human glioblastoma genes and core pathways (2008) (5775)
- Comprehensive molecular characterization of gastric adenocarcinoma (2014) (4496)
- Inferring tumour purity and stromal and immune cell admixture from expression data (2013) (4215)
- Comprehensive molecular profiling of lung adenocarcinoma (2014) (4095)
- Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia. (2013) (3821)
- Integrated genomic characterization of endometrial carcinoma (2013) (3708)
- The Somatic Genomic Landscape of Glioblastoma (2013) (3693)
- Comprehensive genomic characterization of squamous cell lung cancers (2012) (2998)
- Comprehensive genomic characterization of head and neck squamous cell carcinomas (2015) (2860)
- The Immune Landscape of Cancer (2018) (2766)
- Cancer-epigenetics comes of age (1999) (2508)
- Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. (2015) (2211)
- Genomic Classification of Cutaneous Melanoma (2015) (2143)
- Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma. (2010) (2121)
- The Molecular Taxonomy of Primary Prostate Cancer (2015) (2116)
- Integrated Genomic Characterization of Papillary Thyroid Carcinoma (2014) (2007)
- CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer (2006) (1849)
- Comprehensive molecular characterization of urothelial bladder carcinoma (2014) (1748)
- Comprehensive molecular characterization of clear cell renal cell carcinoma (2013) (1724)
- Oncogenic Signaling Pathways in The Cancer Genome Atlas (2018) (1646)
- Absolute quantification of somatic DNA alterations in human cancer (2012) (1607)
- Simplified mammalian DNA isolation procedure. (1991) (1556)
- Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma (2017) (1514)
- Early detection: The power and the promise of DNA methylation markers (2003) (1512)
- Principles and challenges of genome-wide DNA methylation analysis (2010) (1511)
- Pan-cancer patterns of somatic copy-number alteration (2013) (1501)
- Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma (2016) (1474)
- Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer (2017) (1446)
- MethyLight: a high-throughput assay to measure DNA methylation. (2000) (1404)
- Comprehensive Characterization of Cancer Driver Genes and Mutations (2018) (1360)
- Comprehensive Molecular Portraits of Invasive Lobular Breast Cancer (2015) (1332)
- Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer (2018) (1329)
- COBRA: a sensitive and quantitative DNA methylation assay. (1997) (1227)
- Multiplatform Analysis of 12 Cancer Types Reveals Molecular Classification within and across Tissues of Origin (2014) (1192)
- Epigenetic stem cell signature in cancer (2007) (1102)
- Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma. (2017) (1092)
- Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation (2018) (984)
- Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma. (2016) (931)
- Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas (2016) (826)
- Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer. (2010) (788)
- Suppression of intestinal neoplasia by DNA hypomethylation (1995) (781)
- Integrated genomic and molecular characterization of cervical cancer (2017) (762)
- Cancer epigenetics. (2005) (749)
- Interplay between the Cancer Genome and Epigenome (2013) (709)
- Analysis of repetitive element DNA methylation by MethyLight (2005) (703)
- The somatic genomic landscape of chromophobe renal cell carcinoma. (2014) (646)
- The chromatin accessibility landscape of primary human cancers (2018) (646)
- Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina–associated domains (2011) (603)
- Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas (2018) (600)
- Comprehensive and Integrated Genomic Characterization of Adult Soft Tissue Sarcomas (2017) (577)
- Cooperativity between DNA Methyltransferases in the Maintenance Methylation of Repetitive Elements (2002) (572)
- Low-level processing of Illumina Infinium DNA Methylation BeadArrays (2013) (570)
- Epigenetic patterns in the progression of esophageal adenocarcinoma. (2001) (542)
- Genome-scale analysis of aberrant DNA methylation in colorectal cancer. (2012) (507)
- Pathogenic Germline Variants in 10,389 Adult Cancers (2018) (501)
- Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage (2011) (489)
- Survival and development of neonatal rat cardiomyocytes transplanted into adult myocardium. (2002) (487)
- Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients (2018) (471)
- THE ROLE OF DNA METHYLATION IN CANCER GENETICS AND EPIGENETICS (1996) (441)
- DNA Methylation in the Human Cerebral Cortex Is Dynamically Regulated throughout the Life Span and Involves Differentiated Neurons (2007) (427)
- Comprehensive characterization, annotation and innovative use of Infinium DNA methylation BeadChip probes (2016) (423)
- CpG island hypermethylation in human colorectal tumors is not associated with DNA methyltransferase overexpression. (1999) (422)
- Precision and performance characteristics of bisulfite conversion and real-time PCR (MethyLight) for quantitative DNA methylation analysis. (2006) (386)
- Hypermethylated APC DNA in plasma and prognosis of patients with esophageal adenocarcinoma. (2000) (380)
- Patterns of somatic structural variation in human cancer genomes (2020) (377)
- Fields of aberrant CpG island hypermethylation in Barrett's esophagus and associated adenocarcinoma. (2000) (376)
- A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer (2017) (365)
- Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles (2017) (361)
- Association between molecular subtypes of colorectal cancer and patient survival. (2015) (353)
- CpG island methylator phenotype (CIMP) of colorectal cancer is best characterised by quantitative DNA methylation analysis and prospective cohort studies (2006) (352)
- Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas. (2018) (338)
- Alterations of immune response of non-small cell lung cancer with Azacytidine (2013) (335)
- DNA Methylation as a Biomarker for Cardiovascular Disease Risk (2010) (330)
- Whole-genome and multisector exome sequencing of primary and post-treatment glioblastoma reveals patterns of tumor evolution (2015) (307)
- Environmental epigenetics: prospects for studying epigenetic mediation of exposure–response relationships (2012) (295)
- Germ-line passage is required for establishment of methylation and expression patterns of imprinted but not of nonimprinted genes. (1996) (291)
- Association of Breast Cancer DNA Methylation Profiles with Hormone Receptor Status and Response to Tamoxifen (2004) (290)
- The Landscape of Microsatellite Instability in Colorectal and Endometrial Cancer Genomes (2013) (289)
- DNA Methylation: An Alternative Pathway to Cancer (2001) (282)
- Discovery of multi-dimensional modules by integrative analysis of cancer genomic data (2012) (281)
- Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer (2018) (277)
- Cigarette smoking and colorectal cancer risk by molecularly defined subtypes. (2010) (276)
- Widespread Epigenetic Abnormalities Suggest a Broad DNA Methylation Erasure Defect in Abnormal Human Sperm (2007) (271)
- Integrated Molecular Characterization of Uterine Carcinosarcoma. (2017) (271)
- DNA methylation and cancer. (1994) (265)
- DNA Hypomethylation and Ovarian Cancer Biology (2004) (265)
- Integrated Molecular Characterization of Testicular Germ Cell Tumors (2018) (261)
- Epigenetic profiling of somatic tissues from human autopsy specimens identifies tissue- and individual-specific DNA methylation patterns. (2009) (253)
- Quantitative comparison of DNA methylation assays for biomarker development and clinical applications (2016) (251)
- Rebuilding a Damaged Heart: Long-Term Survival of Transplanted Neonatal Rat Cardiomyocytes After Myocardial Infarction and Effect on Cardiac Function (2002) (248)
- Bis-SNP: Combined DNA methylation and SNP calling for Bisulfite-seq data (2012) (239)
- Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas. (2018) (222)
- Epigenetic Analysis of KSHV Latent and Lytic Genomes (2010) (212)
- An epidemiologic and genomic investigation into the obesity paradox in renal cell carcinoma. (2013) (209)
- Mutagenicity of 5-aza-2'-deoxycytidine is mediated by the mammalian DNA methyltransferase. (1997) (204)
- DNA methylation loss in late-replicating domains is linked to mitotic cell division (2018) (202)
- Moving AHEAD with an international human epigenome project (2008) (202)
- Molecular Characterization of MSI-H Colorectal Cancer by MLHI Promoter Methylation, Immunohistochemistry, and Mismatch Repair Germline Mutation Screening (2008) (201)
- Comprehensive molecular characterization of mitochondrial genomes in human cancers (2017) (197)
- The role of DNA methylation in cancer genetic and epigenetics. (1996) (189)
- Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context (2018) (188)
- Hypomethylation and hypermethylation of DNA in Wilms tumors (2002) (181)
- Complete genetic suppression of polyp formation and reduction of CpG-island hypermethylation in Apc(Min/+) Dnmt1-hypomorphic Mice. (2002) (181)
- Breast cancer DNA methylation profiles in cancer cells and tumor stroma: association with HER-2/neu status in primary breast cancer. (2006) (178)
- Comparison of Breast Cancer Molecular Features and Survival by African and European Ancestry in The Cancer Genome Atlas (2017) (178)
- DNA methylation profiles of gastric carcinoma characterized by quantitative DNA methylation analysis (2008) (169)
- Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer (2013) (167)
- SeSAMe: reducing artifactual detection of DNA methylation by Infinium BeadChips in genomic deletions (2018) (161)
- Unique DNA methylation patterns distinguish noninvasive and invasive urothelial cancers and establish an epigenetic field defect in premalignant tissue. (2010) (161)
- Vitamin C Promotes Widespread Yet Specific DNA Demethylation of the Epigenome in Human Embryonic Stem Cells (2010) (153)
- Inferring regulatory element landscapes and transcription factor networks from cancer methylomes (2015) (151)
- Quantitative analysis of associations between DNA hypermethylation, hypomethylation, and DNMT RNA levels in ovarian tumors (2006) (150)
- DNA methylation analysis by MethyLight technology. (2001) (147)
- Analysis of the Association between CIMP and BRAFV600E in Colorectal Cancer by DNA Methylation Profiling (2009) (142)
- The Somatic Genomic Landscape of Glioblastoma (2014) (135)
- Thymidylate synthase: a novel genetic determinant of plasma homocysteine and folate levels (2002) (133)
- Sensitive Detection of DNA Methylation (2003) (124)
- Distinct methylation profiles of glioma subtypes (2003) (124)
- In vivo analysis of Pim-1 deficiency. (1993) (119)
- Identification of a panel of sensitive and specific DNA methylation markers for squamous cell lung cancer (2008) (119)
- Non-invasive diagnosis of early-stage lung cancer using high-throughput targeted DNA methylation sequencing of circulating tumor DNA (ctDNA) (2019) (115)
- Hierarchical clustering of lung cancer cell lines using DNA methylation markers. (2002) (114)
- Kaiso contributes to DNA methylation-dependent silencing of tumor suppressor genes in colon cancer cell lines. (2008) (111)
- A Distinct DNA Methylation Shift in a Subset of Glioma CpG Island Methylator Phenotypes during Tumor Recurrence (2018) (111)
- Identification of a panel of sensitive and specific DNA methylation markers for lung adenocarcinoma (2007) (110)
- Genome-Scale Discovery of DNA-Methylation Biomarkers for Blood-Based Detection of Colorectal Cancer (2012) (109)
- Comprehensive Analysis of Genetic Ancestry and Its Molecular Correlates in Cancer. (2020) (105)
- Phase I trial of continuous infusion 5-aza-2′-deoxycytidine (2003) (105)
- DNA Methyltransferase Deficiency Modifies Cancer Susceptibility in Mice Lacking DNA Mismatch Repair (2002) (102)
- Long-term Epigenetic Therapy with Oral Zebularine Has Minimal Side Effects and Prevents Intestinal Tumors in Mice (2008) (101)
- Correlation of Pathologic Features With CpG Island Methylator Phenotype (CIMP) by Quantitative DNA Methylation Analysis in Colorectal Carcinoma (2006) (100)
- DNA methylation analysis by digital bisulfite genomic sequencing and digital MethyLight (2008) (100)
- Combination Epigenetic Therapy in Advanced Breast Cancer with 5-Azacitidine and Entinostat: A Phase II National Cancer Institute/Stand Up to Cancer Study (2016) (99)
- DNA methylation profiles in diffuse large B-cell lymphoma and their relationship to gene expression status (2008) (98)
- Frequency of deletions of EPCAM (TACSTD1) in MSH2-associated Lynch syndrome cases. (2011) (95)
- Tumor Budding in Colorectal Carcinoma: Confirmation of Prognostic Significance and Histologic Cutoff in a Population-based Cohort (2015) (94)
- Dnmt1 deficiency leads to enhanced microsatellite instability in mouse embryonic stem cells. (2004) (94)
- Smad3 deficiency promotes tumorigenesis in the distal colon of ApcMin/+ mice. (2006) (93)
- DNA Methylation Profiles of Ovarian Epithelial Carcinoma Tumors and Cell Lines (2010) (93)
- The Mutagenic Potential of Duodenoesophageal Reflux (2005) (90)
- The methylenetetrahydrofolate reductase C677T mutation induces cell‐specific changes in genomic DNA methylation and uracil misincorporation: A possible molecular basis for the site‐specific cancer risk modification (2009) (90)
- Erratum: Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles (Cell Reports (2017) 18(11) (2780–2794) (S2211124717302140) (10.1016/j.celrep.2017.02.033)) (2017) (88)
- Impaired interleukin-3 response in Pim-1-deficient bone marrow-derived mast cells. (1993) (87)
- Sex differential in methylation patterns of selected genes in Singapore Chinese (2005) (86)
- Transcription of the intergenic regions of the tubulin gene cluster of Trypanosoma brucei: evidence for a polycistronic transcription unit in a eukaryote. (1987) (85)
- Before and After: Comparison of Legacy and Harmonized TCGA Genomic Data Commons' Data. (2019) (83)
- Role of methionine adenosyltransferase 2A and S-adenosylmethionine in mitogen-induced growth of human colon cancer cells. (2007) (82)
- Targeted methylation sequencing of plasma cell-free DNA for cancer detection and classification (2018) (82)
- Combined bisulfite restriction analysis (COBRA). (2002) (82)
- Oncogenic mechanisms mediated by DNA methylation. (1997) (79)
- Pim-1 levels determine the size of early B lymphoid compartments in bone marrow (1993) (79)
- Reduced Rates of Gene Loss, Gene Silencing, and Gene Mutation in Dnmt1-Deficient Embryonic Stem Cells (2001) (79)
- Distinct DNA methylation profiles in malignant mesothelioma, lung adenocarcinoma, and non-tumor lung. (2003) (78)
- Association of the Colorectal CpG Island Methylator Phenotype with Molecular Features, Risk Factors, and Family History (2015) (78)
- Trans splicing in trypanosomes — archaism or adaptation? (1989) (76)
- The Role of DNA Methylation in the Development and Progression of Lung Adenocarcinoma (2007) (75)
- A comparison of cluster analysis methods using DNA methylation data (2004) (74)
- Gene dysregulation by histone variant H2A.Z in bladder cancer (2013) (71)
- Promoter methylation of the mutated in colorectal cancer gene is a frequent early event in colorectal cancer (2007) (67)
- DNA methylation profile of 28 potential marker loci in malignant mesothelioma. (2007) (65)
- Mature mRNAs of Trypanosoma brucei possess a 5' cap acquired by discontinuous RNA synthesis. (1985) (65)
- In vivo labelling of intermediates in the discontinuous synthesis of mRNAs in Trypanosoma brucei. (1987) (62)
- Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles. (2017) (61)
- Combination epigenetic therapy in metastatic colorectal cancer (mCRC) with subcutaneous 5-azacitidine and entinostat: a phase 2 consortium/stand Up 2 cancer study (2017) (61)
- Global and gene-specific epigenetic patterns in human bladder cancer genomes are relatively stable in vivo and in vitro over time. (2001) (60)
- Genome-Scale Screen for DNA Methylation-Based Detection Markers for Ovarian Cancer (2011) (59)
- DNA Hypermethylation of ESR1 and PGR in Breast Cancer: Pathologic and Epidemiologic Associations (2009) (56)
- Mild depletion of dietary folate combined with other B vitamins alters multiple components of the Wnt pathway in mouse colon. (2007) (55)
- Comprehensive DNA Methylation Analysis on the Illumina ® Infinium ® Assay Platform (2008) (53)
- Associations between colorectal cancer molecular markers and pathways with clinicopathologic features in older women. (2013) (53)
- Promoter Hypermethylation of Tumor Suppressor Genes in Urine from Patients with Cervical Neoplasia (2007) (50)
- Erratum: The somatic genomic landscape of glioblastoma (Cell (2013) 155 (462-477)) (2014) (49)
- Identification of activated enhancers and linked transcription factors in breast, prostate, and kidney tumors by tracing enhancer networks using epigenetic traits (2016) (49)
- 2'-Deoxy-N4-[2-(4-nitrophenyl)ethoxycarbonyl]-5-azacytidine: a novel inhibitor of DNA methyltransferase that requires activation by human carboxylesterase 1. (2008) (49)
- Altered Folate Availability Modifies the Molecular Environment of the Human Colorectum: Implications for Colorectal Carcinogenesis (2011) (45)
- Postmenopausal hormone therapy and colorectal cancer risk by molecularly defined subtypes among older women (2011) (43)
- Rapid and quantitative method of allele-specific DNA methylation analysis. (2006) (42)
- Ovarian Cancer Early Detection Claims Are Biased (2008) (42)
- Microcell-mediated chromosome transfer identifies EPB41L3 as a functional suppressor of epithelial ovarian cancers. (2010) (41)
- Sex differences in oncogenic mutational processes (2019) (41)
- Associations Between Intake of Folate and Related Micronutrients with Molecularly Defined Colorectal Cancer Risks in the Iowa Women's Health Study (2012) (40)
- Specific Variants in the MLH1 Gene Region May Drive DNA Methylation, Loss of Protein Expression, and MSI-H Colorectal Cancer (2010) (40)
- Molecular Features of Cancers Exhibiting Exceptional Responses to Treatment. (2020) (38)
- DNA methylation profiles of female steroid hormone-driven human malignancies. (2006) (37)
- DNA defects, epigenetics, and gene expression in cancer-adjacent breast: a study from The Cancer Genome Atlas (2016) (35)
- Hormone therapy, DNA methylation and colon cancer. (2010) (34)
- Clinical applications of DNA methylation biomarkers in colorectal cancer. (2013) (34)
- Loss of function of Trp53, but not Apc, leads to the development of esophageal adenocarcinoma in mice with jejunoesophageal reflux. (1999) (33)
- Mismatch repair deficiency and CpG island hypermethylation in sporadic colon adenocarcinomas. (2001) (33)
- Multiscale Representation of Genomic Signals (2014) (33)
- A pgk::hprt fusion as a selectable marker for targeting of genes in mouse embryonic stem cells: disruption of the T-cell receptor delta-chain-encoding gene. (1991) (32)
- Analysis of complex methylation data. (2002) (31)
- Stable introduction of exogenous DNA into Trypanosoma brucei. (1987) (31)
- Analysis of Pim-1 function in mutant mice. (1993) (30)
- Transgenic mice for the preparation of hygromycin-resistant primary embryonic fibroblast feeder layers for embryonic stem cell selections. (1995) (30)
- Sensitivity and reproducibility of standardized-competitive RT-PCR for transcript quantification and its comparison with real time RT-PCR (2004) (29)
- Mouse model systems to study multistep tumorigenesis. (1994) (28)
- Prolonged culture of normal chorionic villus cells yields ICF syndrome-like chromatin decondensation and rearrangements (2003) (28)
- Locking in on the human methylome (2009) (28)
- In epigenetic therapy, less is more. (2012) (27)
- Diet, cancer and aging in DNA mismatch repair deficient mice. (2002) (25)
- A blueprint for an international cancer epigenome consortium. A report from the AACR Cancer Epigenome Task Force. (2012) (23)
- Clinicopathologic Risk Factor Distributions for MLH1 Promoter Region Methylation in CIMP-Positive Tumors (2015) (22)
- Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples (2020) (22)
- Controlled turnover and 3' trimming of the trans splicing precursor of Trypanosoma brucei. (1987) (21)
- Reduction of pancreatic acinar cell tumor multiplicity in Dnmt1 hypomorphic mice. (2011) (20)
- Promoter Methylation Analysis Reveals That KCNA5 Ion Channel Silencing Supports Ewing Sarcoma Cell Proliferation (2015) (20)
- Promoter hypermethylation: a new therapeutic target emerges in urothelial cancer. (2005) (20)
- DNA methylator and mismatch repair phenotypes are not mutually exclusive in colorectal cancer cell lines (2000) (18)
- Alcohol Intake and Colorectal Cancer Risk by Molecularly Defined Subtypes in a Prospective Study of Older Women (2011) (18)
- Non-specific filtering of beta-distributed data (2014) (17)
- Gene-Specific Methylation and Subsequent Risk of Colorectal Adenomas among Participants of the Polyp Prevention Trial (2005) (17)
- Systematic Assessment of Tumor Purity and Its Clinical Implications (2020) (17)
- Association of high microvessel αvβ3 and low PTEN with poor outcome in stage 3 neuroblastoma: rationale for using first in class dual PI3K/BRD4 inhibitor, SF1126. (2017) (16)
- Advances in Brief Complete Genetic Suppression of Polyp Formation and Reduction of CpG-Island Hypermethylation in ApcMin / Dnmt 1-Hypomorphic Mice 1 (2002) (15)
- DNA methylation dynamics and dysregulation delineated by high-throughput profiling in the mouse (2022) (14)
- Cancer Risks for the Relatives of Colorectal Cancer Cases with a Methylated MLH1 Promoter Region: Data from the Colorectal Cancer Family Registry (2011) (14)
- MethyLight and Digital MethyLight. (2018) (12)
- Transcriptional heterogeneity in the lactase gene within cell-type is linked to the epigenome (2017) (12)
- The Exceptional Responders Initiative: Feasibility of A National Cancer Institute Pilot Study. (2020) (12)
- Abstract LB-173: Genome-scale analysis of aberrant DNA methylation in colorectal cancer (2011) (11)
- The USC Epigenome Center. (2009) (11)
- Epigenetic Subgroups of Esophageal and Gastric Adenocarcinoma with Differential GATA5 DNA Methylation Associated with Clinical and Lifestyle Factors (2011) (11)
- Beta regression improves the detection of differential DNA methylation for epigenetic epidemiology (2016) (11)
- Whole-genome characterization of lung adenocarcinomas lacking alterations in the RTK/RAS/RAF pathway (2021) (10)
- γ-Glutamyl hydrolase modulation significantly influences global and gene-specific DNA methylation and gene expression in human colon and breast cancer cells (2014) (9)
- Association of high microvessel αvβ3 and low PTEN with poor outcome in stage 3 neuroblastoma: rationale for using first in class dual PI3K/BRD4 inhibitor, SF1126 (2016) (9)
- CpG Island Methylator Phenotype in Human Colorectal Cancer Is Tightly Associated with BRAF Mutation and Underlies Sporadic Mismatch Repair Deficiency. (2006) (9)
- Cluster analysis for DNA methylation profiles having a detection threshold (2006) (8)
- Effects of folylpolyglutamate synthase modulation on global and gene-specific DNA methylation and gene expression in human colon and breast cancer cells. (2016) (8)
- Tumor budding in colorectal carcinoma (2015) (8)
- Multi-cancer molecular signatures and their interrelationships (2013) (7)
- Repeated assessment by high-throughput assay demonstrates that sperm DNA methylation levels are highly reproducible. (2011) (7)
- Mouse models in DNA-methylation research. (2000) (7)
- The REMOTE-control system: a system for reversible and tunable control of endogenous gene expression in mice (2017) (7)
- Abstract S2-04: Comprehensive molecular characterization of invasive lobular breast tumors (2015) (7)
- Epigenomics-based diagnostics. (2010) (6)
- Distinct epigenetic shift in a subset of Glioma CpG island methylator phenotype (G-CIMP) during tumor recurrence (2017) (6)
- Abstract 3302: The molecular landscape of oncogenic signaling pathways in The Cancer Genome Atlas (2018) (6)
- Determination of the CpG Island Methylator Phenotype (CIMP) in colorectal cancer using MethyLight (2006) (6)
- Dnmt 1 deficiency leads to enhanced microsatellite instability in mouse embryonic stem cells (2004) (6)
- Multiomics in primary and metastatic breast tumors from the AURORA US network finds microenvironment and epigenetic drivers of metastasis (2022) (6)
- Alterations in deoxyribonucleic acid (DNA) methylation patterns of Calca, Timp3, Mmp2, and Igf2r are associated with chronic cystitis in a cyclophosphamide-induced mouse model. (2013) (6)
- Modeling Exposures for DNA Methylation Profiles (2006) (5)
- Comprehensive molecular characterization and analysis of muscle-invasive urothelial carcinomas. (2017) (5)
- Phase I trial of TRC102 (methoxyamine HCl) in combination with temozolomide in patients with relapsed solid tumors and lymphomas (2020) (5)
- The molecular landscape of oncogenic signaling pathways in The Cancer Genome Atlas (2018) (4)
- Abstract GS3-08: Multiplatform analysis of matched primary and metastatic breast tumors from the AURORA US Network (2020) (4)
- Epi meets genomics: Technologies for finding and reading the 5th base (2005) (4)
- Bis-SNP: Combined DNA methylation and SNP calling for Bisulfite-seq data (2012) (4)
- Ancestry-specific predisposing germline variants in cancer (2020) (4)
- Cell division drives DNA methylation loss in late-replicating domains in primary human cells (2022) (4)
- stem cells is a hallmark of cancer Age-dependent DNA methylation of genes that are suppressed in Material Supplemental (2010) (4)
- Differences in Genome-wide DNA Methylation Profiles in Breast Milk by Race and Lactation Duration (2019) (3)
- Comparison of Breast CancerMolecular Features and Survival byAfrican and EuropeanAncestry in The Cancer GenomeAtlas (2017) (3)
- Abstract 5383: Non-invasive diagnosis of early-stage lung cancer via targeted high-throughput DNA methylation sequencing of circulating tumor DNA (ctDNA) (2017) (3)
- Environmental epigenetics: prospects for studying epigenetic mediation of exposure–response relationships (2012) (3)
- Modeling measurement error in tumor characterization studies (2011) (3)
- Inferring regulatory element landscapes and transcription factor networks from cancer methylomes (2015) (2)
- 146 Diabetes Mellitus (DM) and Colorectal Cancer (CRC) Risk by Molecularly-Defined Subtypes in a Prospective Study of Older Women (2010) (2)
- Tea and Chocolate Consumption and Colorectal Cancer Risk by Molecularly Defined Subtypes in a Prospective Cohort Study of Older Women: Presidential Poster: 2094 (2013) (2)
- FIELDS OF ABERREANT CPG ISLAND HYPERMETHYLATION IN BARRETTE’S ESOPHAGUS AND ASSOCIATED ADENOCARCINOMAS (2000) (2)
- Bile salt-induced mutation In vitro (1998) (2)
- DNA methylation profile of 1501 loci in bladder cancer shows evidence of a field defect (2008) (2)
- Abstract 2969: Progress in The Cancer Genome Atlas bladder cancer project (2015) (2)
- Analysis of germline-driven ancestry-associated gene expression in cancers (2022) (1)
- Comprehensive molecular profiling of urothelial bladder cancer at the DNA, RNA, and protein levels: A TCGA project. (2014) (1)
- Genome-Wide DNA Methylation Analysis of Patients with Myelodysplastic Syndrome After Azacitidine Treatment. (2009) (1)
- Comprehensive characterization of 412 muscle invasive urothelial carcinomas: Final analysis of The Cancer Genome Atlas (TCGA) project. (2016) (1)
- Analytical protocol to identify local ancestry-associated molecular features in cancer (2021) (1)
- Epigenetic Cancer Therapy Makes Headway (2006) (1)
- Author Correction: Pan-cancer analysis of whole genomes (2023) (1)
- ELMER: An R/Bioconductor Tool Inferring Regulatory Element Landscapes and Transcription Factor Networks Using Methylomes (2016) (1)
- All Things in Moderation: Prevention of Intestinal Adenomas by DNA Hypomethylation (2016) (1)
- Integrated DNA Methylation/RNA Profiling in Middle Temporal Gyrus of Alzheimer’s Disease (2023) (1)
- DNA methylation markers for ovarian cancer (2010) (1)
- Molecular subtypes of colorectal cancer in relation to disease survival. (2014) (1)
- Non-specific filtering of beta-distributed data (2014) (1)
- Comprehensive analysis of cancer stemness (2018) (1)
- Whole-genome characterization of lung adenocarcinomas lacking alterations in the RTK/RAS/RAF pathway (2021) (1)
- In vivo Application of the REMOTE-control System for the Manipulation of Endogenous Gene Expression. (2019) (1)
- Identification of activated enhancers and linked transcription factors in breast, prostate, and kidney tumors by tracing enhancer networks using epigenetic traits (2016) (1)
- High-resolution profiling of lung adenocarcinoma identifies expression subtypes with specific biomarkers and clinically relevant vulnerabilities. (2022) (1)
- Procedure for analysis of DNA methylation high performance. (2000) (0)
- Abstract P6-10-07: Differences in genome-wide DNA methylation levels in breast milk by race and lactation duration (2018) (0)
- Abstract P1-05-11: Comprehensive comparison of breast cancer molecular portraits by African and European ancestry in the cancer genome atlas (2017) (0)
- How epigenomics broke the mold: an interview with Peter W Laird. (2022) (0)
- Resource Reveals Molecular Classification Multiplatform Analysis of 12 Cancer Types within and across Tissues of Origin (0)
- DNA methylation loss in late-replicating domains is linked to mitotic cell division (2018) (0)
- DNA methylation markers associated with serous ovarian cancer subtypes (2011) (0)
- DNA Methylation Profiles in Cancer Cells and Tumor Stroma: Association with HER-2/neu Status in Primary Breast Cancer. (2006) (0)
- Abstract 1620: Effects of γ-glutamyl hydrolase and folylpolyglutamyl synthase modulation on gene-specific promoter CpG island methylation (2011) (0)
- High-resolution lung adenocarcinoma expression subtypes identify tumors with dependencies on MET, CDK4, CDK6, and PD-L1 (2022) (0)
- The mutagenic potential of duodeno-gastroesophageal reflux (2000) (0)
- FREE with the March issue of Trends in Molecular Medicine (2002) (0)
- Author Correction: Patterns of somatic structural variation in human cancer genomes (2020) (0)
- Integrative Genomic Analy sis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles Graphical (2017) (0)
- Abstract SY15-01: Modeling the initiation of Ewing sarcoma in human neural crest stem cells (2011) (0)
- Accepted Manuscript Association Between Molecular Subtypes of Colorectal Cancer and Patient Survival (2014) (0)
- Comparative Molecular An alysis of Gastrointestinal Adenocarcinomas (0)
- Author Correction: The evolutionary history of 2,658 cancers (2023) (0)
- Stable introduction ofexogenous DNA intoTrypanosoma brucei (1987) (0)
- Abstract PL02-01: Cancer genetic and epigenetic interactions. (2013) (0)
- Decision letter: A rat epigenetic clock recapitulates phenotypic aging and co-localizes with heterochromatin (2020) (0)
- Abstract 128: Comprehensive molecular characterization of 412 muscle-invasive urothelial bladder carcinomas: final analysis of The Cancer Genome Atlas (TCGA) project (2016) (0)
- Effects of γ‐glutamyl hydrolase modulation on CpG promoter DNA methylation and gene expression in human colon cancer cells (2013) (0)
- Field Defect in Premalignant Tissue and Invasive Urothelial Cancers and Establish an Epigenetic Unique DNA Methylation Patterns Distinguish Noninvasive (2010) (0)
- Effects of folylpolyglutamate synthase modulation on CpG promoter DNA methylation and gene expression in human colon cancer cells (2013) (0)
- Abstract B130: The intratumoral heterogeneity of glioblastoma suggests a pivotal role for clonal evolution. (2013) (0)
- γ-Glutamyl hydrolase modulation significantly influences global and gene-specific DNA methylation and gene expression in human colon and breast cancer cells (2014) (0)
- THE P53 PATHWAY AND ANCESTRAL PROGENITORS ARE ASSOCIATED WITH TUMOR RECURRENCE IN GLIOBLASTOMA (2014) (0)
- DNA methylation and HOMER data for primary and recurrent glioma cases. (2018) (0)
- Pim-1 Levels Determine the Size o f Early B Lymphoid Compartments in Bone Marrow By Jos Domen (2003) (0)
- Abstract 5518: Clinicopathologic associations with colorectal cancer molecular pathways in a cohort study of older women: (2012) (0)
- Cancer esearch or and Stem Cell Biology que DNA Methylation Patterns Distinguish Noninvasive Invasive Urothelial Cancers and Establish an R enetic Field Defect in Premalignant Tissue (2010) (0)
- Abstract 5312: The effect ofDnmt1overexpression on intestinal tumorigenesis (2018) (0)
- Abstract 3288: The KCNA5 promoter is hypermethylated in Ewing sarcoma and silencing contributes to cell proliferation (2015) (0)
- Mouse Models for the Study of DNA Methylation (2004) (0)
- Abstract 31: DNA Methylation Analysis of Radiated Skin Reveals Chonic Inflammation with a Predominance of Polymorphonuclear Granulocytes (2014) (0)
- 147 DNA methylation profile of 28 candidate marker loci in malignant mesothelioma (2006) (0)
- Abstract LB-233: Modeling Ewing sarcoma initiation in human neural crest stem cells (2011) (0)
- Epigenetic patterns differ in different types of cancer (2005) (0)
- ole of Methionine Adenosyltransferase 2 A and S-adenosylmethionine in itogen-Induced Growth of Human Colon Cancer Cells (2007) (0)
- DNA Methylation in Colorectal Cancer: Multiple Facets of Tumorigenesis (2009) (0)
- Genome wide mapping of histone methylation reveals a distinct epigenomic signature in human pluripotent stem cells (2010) (0)
- Stable introduction of exogenoud DNA into Trypsnosoma brucei (1987) (0)
- Test Procedure DNA methylation high performance (2000) (0)
- Abstract A44: Coffee consumption and colorectal cancer risk by molecularly defined subtypes in a prospective cohort study of older women (2013) (0)
- Abstract 984: Alteration of the p53 pathway is associated with subclonal tumor progression in glioblastoma (2014) (0)
- Alterations in the DNA Methylation Patterns of Calca, Timp3, Mmp2, and Igf2r are Associated with Chronic Cystitis in a Cyclophosphamide-induced Mouse Model (2013) (0)
- Abstract 5381: A highly sensitive method for noninvasive cancer profiling through targeted methylation sequencing of circulating cell-free DNA (2017) (0)
- DNA methylation patterns predict clinical outcome in esophageal adenocarcinoma (2001) (0)
- Abstract 3310: Non-invasive diagnosis of colorectal cancer via targeted high-throughput DNA methylation sequencing of circulating tumor DNA (ctDNA) (2018) (0)
- DNA Methylation Data Analysis (2012) (0)
- Author Correction: Inferring structural variant cancer cell fraction (2022) (0)
- 722 IDENTIFICATION OF EPIGENETIC CHANGES IN CHRONIC BLADDER INFLAMMATION (2012) (0)
- A method with high capacity for analysis of DNA methylation (2000) (0)
- Abstract 4922: Patterns of tumor evolution in high grade serous ovarian carcinoma (2012) (0)
- Abstract 987: Comprehensive characterization of urothelial bladder cancer: a TCGA Project update (2014) (0)
- S1950 Folate Intake and Colorectal Cancer Risks By CIMP and BRAF-Mutation Status Among Older Women (2009) (0)
- DAB2IP is a bifunctional tumor suppressor that regulates wildtype RAS and inflammatory cascades in KRAS mutant colon cancer. (2023) (0)
- Exploring the cancer methylome (2012) (0)
- Abstract 4492: Colorectal cancer survival by molecular subtypes in a population-based cohort of older women (2012) (0)
- Gene dysregulation by histone variant H2A.Z in bladder cancer (2013) (0)
- An intermediate methylation signature is associated with improved patient survival and a distinct global mRNA expression profile in glioblastoma: An interim analysis of The Cancer Genome Atlas data (2008) (0)
- Integrated genomic characterization of oesophageal carcinoma (2017) (0)
- Comprehensivemolecularcharacterization of human colon and rectal cancer (2012) (0)
- Ovarian Cancer Early Detection Claims Are Biased. Authors' reply (2008) (0)
- Abstract 5895: Whole-genome characterization of lung adenocarcinomas lacking alterations in RTK/RAS/RAF/MAPK pathway (2020) (0)
- Abstract LB-373: Comprehensive analysis of cancer stemness (2018) (0)
- P3.02-008 Non-Invasive Diagnosis of Solitary Pulmonary Nodules Using High-Throughput Targeted DNA Methylation Sequencing of Circulating Tumor DNA (2017) (0)
- A method for analysis of DNA methylation at a high throughput rate (2000) (0)
- Abstract #LB-169: DNA methylation profiling reveals a field defect in bladders with cancer and a distinct hypomethylated pattern in non-invasive bladder tumors (2009) (0)
- A broad epigenetic defect of abnormal human sperm is suggested by elevated methylation of numerous DNA sequences in sperm of low concentration, poor morphology and poor motility (2007) (0)
- GENO-06A PAN-GLIOMA CHARACTERIZATION OF GENOMIC, EPIGENOMIC AND TRANSCRIPTOMIC ACTIVITIES REVEALS NOVEL RELATIONSHIPS BETWEEN HISTOLOGICAL SUBTYPES AND MOLECULAR SIGNATURES (2015) (0)
- P31 DNA methylation profiles in breast cancer — relation to hormone receptors and role in response to adjuvant endocrine treatment (2004) (0)
- Abstract LB176: Multiplatform analysis of matched primary and metastatic breast tumors from the AURORA US Network identifies microenvironment features as drivers of metastasis (2022) (0)
- PROCEDURE WITH HIGH CAPACITY FOR ANALYSIS OF DNA methylation (2000) (0)
- Uni and Epig (2010) (0)
- Abstract LB-004: Molecular hallmarks of cancer: Stemness (2017) (0)
- Abstract A115: Alcohol use and molecularly defined colorectal cancer risks in a prospective study of older women (2010) (0)
- Update on Epigenetic Agents in the Treatment of BC (2014) (0)
- Author Correction: Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples (2020) (0)
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What Schools Are Affiliated With Peter W Laird?
Peter W Laird is affiliated with the following schools:
