Philip Majerus

Q: What Schools Are Affiliated With Philip Majerus

Philip Majerus is affiliated with the following schools: Monash University, Kagoshima University, Teikyo University, Washington University in St. Louis, University of California, Berkeley, University of British Columbia, University of Notre Dame

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Philip Majerus

Biology

#3279

World Rank

#5034

Historical Rank

#1347

USA Rank

Biochemistry

#478

World Rank

#562

Historical Rank

#171

USA Rank

biology Degrees

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Biology

Philip Majerus's Degrees

PhD Biochemistry University of California, Berkeley
Bachelors Chemistry University of California, Berkeley

Why Is Philip Majerus Influential?

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According to Wikipedia, Philip Warren Majerus was an American biochemist who confirmed the cardiovascular benefits of aspirin. After graduating from medical school and completing a residency at Massachusetts General Hospital, Majerus conducted research at the National Heart Institute before becoming a faculty member at the Washington University School of Medicine.

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Philip Majerus's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Collaborative overview of randomised trials of antiplatelet therapy Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients (1994) (3667)
Acetylation of prostaglandin synthase by aspirin. (1975) (952)
The mechanism of the effect of aspirin on human platelets. I. Acetylation of a particulate fraction protein. (1975) (862)
The 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-triphosphate 5-phosphatase. (1996) (672)
The metabolism of phosphoinositide-derived messenger molecules. (1986) (583)
Inhibition of platelet prostaglandin synthetase by oral aspirin. (1978) (564)
Diglyceride lipase: a pathway for arachidonate release from human platelets. (1979) (540)
SopB, a protein required for virulence of Salmonella dublin, is an inositol phosphate phosphatase. (1998) (445)
Thrombomodulin is found on endothelium of arteries, veins, capillaries, and lymphatics, and on syncytiotrophoblast of human placenta (1985) (412)
Structure and function of thrombomodulin: a natural anticoagulant. (1990) (410)
Properties of the factor Xa binding site on human platelets. (1978) (382)
Inositol phosphate biochemistry. (1992) (369)
A thrombin-sensitive protein of human platelet membranes. (1971) (313)
Thrombomodulin is present in human plasma and urine. (1985) (304)
Inositol phosphates: synthesis and degradation. (1988) (288)
Protein kinase C phosphorylates human platelet inositol trisphosphate 5′-phosphomonoesterase, increasing the phosphatase activity (1986) (278)
Isolation and properties of a thrombin-sensitive protein of human platelets. (1972) (275)
Inositol polyphosphate 4-phosphatase II regulates PI3K/Akt signaling and is lost in human basal-like breast cancers (2010) (274)
Characterization of 1,2-diacylglycerol hydrolysis in human platelets. Demonstration of an arachidonoyl-monoacylglycerol intermediate. (1983) (262)
Cyclic adenosine 3',5'-monophosphate inhibits the availability of arachidonate to prostaglandin synthetase in human platelet suspensions. (1977) (260)
The binding of thrombin to the surface of human platelets. (1974) (258)
The protein deficient in Lowe syndrome is a phosphatidylinositol-4,5-bisphosphate 5-phosphatase. (1995) (245)
Prevention of thrombosis in patients on hemodialysis by low-dose aspirin. (1979) (239)
Arachidonate metabolism in vascular disorders. (1983) (239)
Multiple forms of an inositol polyphosphate 5-phosphatase form signaling complexes with Shc and Grb2 (1996) (235)
Mutations in the inositol polyphosphate-5-phosphatase E gene link phosphatidyl inositol signaling to the ciliopathies (2009) (234)
The Role of Phosphatases in Inositol Signaling Reactions* (1999) (231)
Recent insights in phosphatidylinositol signaling (1990) (217)
Purification and properties of human coagulation factor VII. (1980) (215)
Thrombin-induced protein phosphorylation in human platelets. (1975) (214)
Cultured human skin fibroblasts and arterial cells produce a labile platelet-inhibitory prostaglandin. (1977) (212)
Discovery of an arachidonoyl coenzyme A synthetase in human platelets. (1982) (210)
The measurement of thrombin in clotting blood by radioimmunoassay. (1976) (207)
The Inositol 5′-Phosphatase SHIP Binds to Immunoreceptor Signaling Motifs and Responds to High Affinity IgE Receptor Aggregation* (1996) (201)
Isolation and quantitation of the platelet membrane glycoprotein deficient in thrombasthenia using a monoclonal hybridoma antibody. (1980) (198)
The activation loop of phosphatidylinositol phosphate kinases determines signaling specificity. (2000) (196)
Characterization of prostacyclin synthesis in cultured human arterial smooth muscle cells, venous endothelial cells and skin fibroblasts (1979) (188)
Human thrombomodulin: complete cDNA sequence and chromosome localization of the gene. (1987) (182)
Isolation of human platelets and platelet surface membranes. (1974) (182)
Isolation and characterization of thrombomodulin from human placenta. (1984) (180)
Thrombin-induced hydrolysis of phosphatidylinositol in human platelets. (1980) (180)
Inherited predisposition to thrombosis (1993) (177)
Identification, cloning, and expression of a cytosolic megakaryocyte protein-tyrosine-phosphatase with sequence homology to cytoskeletal protein 4.1. (1991) (168)
Purification and characterization of human coagulation factor V. (1981) (163)
Definition of a metal-dependent/Li(+)-inhibited phosphomonoesterase protein family based upon a conserved three-dimensional core structure. (1995) (162)
Hydrolysis of polyphosphoinositides by purified sheep seminal vesicle phospholipase C enzymes. (1984) (161)
Identification and properties of two distinct phosphatidylinositol-specific phospholipase C enzymes from sheep seminal vesicular glands. (1982) (160)
Isolation of a phosphomonoesterase from human platelets that specifically hydrolyzes the 5-phosphate of inositol 1,4,5-trisphosphate. (1985) (159)
Acetyl coenzyme A carboxylase. The roles of synthesis and degradation in regulation of enzyme levels in rat liver. (1969) (157)
Phosphoinositide turnover provides a link in stimulus—response coupling (1985) (154)
Interaction of coagulation factor Xa with human platelets. (1977) (151)
Cell Lines from Kidney Proximal Tubules of a Patient with Lowe Syndrome Lack OCRL Inositol Polyphosphate 5-Phosphatase and Accumulate Phosphatidylinositol 4,5-Bisphosphate* (1998) (151)
Phosphoinositide interconversion in thrombin-stimulated human platelets. (1985) (145)
The synthesis of sulfated dextran beads for isolation of human plasma coagulation factors II, IX, and X. (1980) (144)
Sensitivity of fatty acid cyclooxygenase from human aorta to acetylation by aspirin. (1978) (141)
The turnover of thrombin-thrombomodulin complex in cultured human umbilical vein endothelial cells and A549 lung cancer cells. Endocytosis and degradation of thrombin. (1985) (138)
Phosphatidylinositol-4-phosphate 5-Kinase Isozymes Catalyze the Synthesis of 3-Phosphate-containing Phosphatidylinositol Signaling Molecules* (1997) (137)
The inositol polyphosphate 5-phosphatase Ocrl associates with endosomes that are partially coated with clathrin. (2004) (132)
The Isolation and Characterization of a cDNA Encoding Phospholipid-specific Inositol Polyphosphate 5-Phosphatase* (2000) (131)
The effects of mepacrine and p-bromophenacyl bromide on arachidonic acid release in human platelets. (1982) (130)
Patients with congenital factor V deficiency have decreased factor Xa binding sites on their platelets. (1978) (128)
Factor Va-dependent binding of factor Xa to human platelets. (1980) (128)
Thrombomodulin, an endothelial anticoagulant protein, is absent from the human brain. (1986) (123)
Nuclear phosphatidylinositols decrease during S-phase of the cell cycle in HeLa cells. (1994) (123)
Production of phosphoinositide-derived messengers (1984) (123)
Properties of Type II Inositol Polyphosphate 5-Phosphatase (*) (1995) (122)
The metabolism of tris- and tetraphosphates of inositol by 5-phosphomonoesterase and 3-kinase enzymes. (1987) (121)
Isolation and characterization of the inositol cyclic phosphate products of polyphosphoinositide cleavage by phospholipase C. Physiological effects in permeabilized platelets and Limulus photoreceptor cells. (1985) (120)
Acetylation of prostaglandin synthetase by aspirin. Purification and properties of the acetylated protein from sheep vesicular gland. (1977) (118)
Inositol Hexakisphosphate Binds to Clathrin Assembly Protein 3 (AP-3/AP180) and Inhibits Clathrin Cage Assembly in Vitro(*) (1995) (117)
Modulation of phosphatidylinositol-specific phospholipase C activity by phospholipid interactions, diglycerides, and calcium ions. (1982) (115)
Formation of phosphatidylinositol 3-phosphate by isomerization from phosphatidylinositol 4-phosphate. (1991) (111)
The regulation of fatty acid biosynthesis in rat hepatomas. (1968) (108)
Phosphoinositide-specific Inositol Polyphosphate 5-Phosphatase IV Inhibits Akt/Protein Kinase B Phosphorylation and Leads to Apoptotic Cell Death* (2002) (108)
Deficiency of factor Xa-factor Va binding sites on the platelets of a patient with a bleeding disorder. (1979) (107)
Inositol 1,3,4-Trisphosphate 5/6-Kinase Associates with the COP9 Signalosome by Binding to CSN1* (2002) (106)
The fatty acid composition of phosphatidylinositol from thrombin-stimulated human platelets. (1981) (105)
Phosphatidylinositol 3-phosphate is present in normal and transformed fibroblasts and is resistant to hydrolysis by bovine brain phospholipase C II. (1989) (98)
Glutathione biosynthesis in human erythrocytes. I. Identification of the enzymes of glutathione synthesis in hemolysates. (1971) (98)
The Isolation and Characterization of cDNA Encoding Human and Rat Brain Inositol Polyphosphate 4-Phosphatase (*) (1995) (96)
Arachidonate release and phosphatidic acid turnover in stimulated human platelets. (1983) (95)
The identification and characterization of two phosphatidylinositol-4,5-bisphosphate 4-phosphatases. (2005) (95)
The binding of phytohemagglutinins to human platelet plasma membranes. (1972) (94)
Characterization of myotubularin-related protein 7 and its binding partner, myotubularin-related protein 9 (2003) (94)
Overexpression of the inositol phosphatase SopB in human 293 cells stimulates cellular chloride influx and inhibits nuclear mRNA export. (2001) (92)
Bad blood by mutation (1994) (90)
Glutathione synthetase deficiency as a cause of hereditary hemolytic disease. (1970) (89)
The protein tyrosine phosphatase SHP-1 regulates integrin-mediated adhesion of macrophages (1998) (89)
Arachidonoyl-CoA synthetase. Separation from nonspecific acyl-CoA synthetase and distribution in various cells and tissues. (1985) (87)
THE ACYL CARRIER PROTEIN OF FATTY ACID SYNTHESIS: PURIFICATION, PHYSICAL PROPERTIES, AND SUBSTRATE BINDING SITE. (1964) (87)
Isolation of vitamin B12-binding proteins using affinity chromatography. 3. Purification and properties of human plasma transcobalamin II. (1972) (86)
Lipid metabolism in human platelets. (1969) (85)
Identification of myotubularin as the lipid phosphatase catalytic subunit associated with the 3-phosphatase adapter protein, 3-PAP (2003) (85)
Hydrolysis of phosphatidylinositol 3,4-bisphosphate by inositol polyphosphate 4-phosphatase isolated by affinity elution chromatography. (1994) (85)
Thrombomodulin, an endothelial anticoagulant protein, is absent from the human brain (1986) (85)
Cloning and expression of a cytosolic megakaryocyte protein-tyrosine-phosphatase with sequence homology to retinaldehyde-binding protein and yeast SEC14p. (1992) (85)
Identity of inositol 1,2-cyclic phosphate 2-phosphohydrolase with lipocortin III. (1990) (84)
ACYL-CARRIER PROTEIN. II. INTERMEDIARY REACTIONS OF FATTY ACID SYNTHESIS. (1964) (84)
Lack of covalent modification of prostaglandin synthetase (cyclo-oxygenase) by indomethacin. (1977) (84)
Inositol polyphosphate 1-phosphatase from calf brain. Purification and inhibition by Li+, Ca2+, and Mn2+. (1987) (84)
The cDNA Cloning and Characterization of Inositol Polyphosphate 4-Phosphatase Type II (1997) (84)
The interaction of human coagulation factor Va with platelets. (1982) (81)
Guanine nucleotides stimulate soluble phosphoinositide-specific phospholipase C in the absence of membranes. (1986) (81)
Thrombomodulin as a marker for vascular tumors. Comparative study with factor VIII and Ulex europaeus I lectin. (1987) (80)
Lipid metabolism in human platelets. I. Evidence for a complete fatty acid synthesizing system. (1969) (80)
Multiple forms of the SH2-containing inositol phosphatase, SHIP, are generated by C-terminal truncation. (1998) (80)
Isolation of vitamin B12-binding proteins using affinity chromatography. I. Preparation and properties of vitamin B12-sepharose. (1972) (79)
[18] Purification of human coagulation factors II, IX, and X using sulfated dextran beads (1981) (78)
Isolation of Inositol 1,3,4-Trisphosphate 5/6-Kinase, cDNA Cloning, and Expression of the Recombinant Enzyme (*) (1996) (78)
ACYL CARRIER PROTEIN. IV. THE IDENTIFICATION OF 4'-PHOSPHOPANTETHEINE AS THE PROSTHETIC GROUP OF THE ACYL CARRIER PROTEIN. (1965) (76)
Phosphatidylinositol signalling reactions. (1998) (76)
Coagulation factor Va binds to human umbilical vein endothelial cells and accelerates protein C activation. (1984) (75)
The Pathway for the Production of Inositol Hexakisphosphate in Human Cells* (2005) (74)
Isolation and characterization of the inositol cyclic phosphate products of phosphoinositide cleavage by phospholipase C. Metabolism in cell-free extracts. (1986) (74)
Biosynthesis of coagulation Factor V by a human hepatocellular carcinoma cell line. (1984) (74)
Type I phosphatidylinositol-4,5-bisphosphate 4-phosphatase regulates stress-induced apoptosis (2007) (73)
High affinity esterification of eicosanoid precursor fatty acids by platelets. (1983) (72)
The Synthesis of Inositol Hexakisphosphate (2002) (72)
Regulation of PI(3)K/Akt signalling and cellular transformation by inositol polyphosphate 4‐phosphatase‐1 (2009) (72)
Inositol 1,3,4-Trisphosphate 5/6-Kinase Is a Protein Kinase That Phosphorylates the Transcription Factors c-Jun and ATF-2* (2001) (72)
Identification and isolation of a 75-kDa inositol polyphosphate-5-phosphatase from human platelets. (1989) (70)
Inhibition of human platelet aggregation by monovalent antifibrinogen antibody fragments. (1975) (70)
Mutation of the conserved domains of two inositol polyphosphate 5-phosphatases. (1996) (70)
Inositol cyclic phosphates are produced by cleavage of phosphatidylphosphoinositols (polyphosphoinositides) with purified sheep seminal vesicle phospholipase C enzymes. (1985) (70)
The Human Homolog of the Rat Inositol Phosphate Multikinase Is an Inositol 1,3,4,6-Tetrakisphosphate 5-Kinase* (2002) (69)
The structure and function of mouse thrombomodulin. Phorbol myristate acetate stimulates degradation and synthesis of thrombomodulin without affecting mRNA levels in hemangioma cells. (1988) (68)
Aspirin as a quantitative acetylating reagent for the fatty acid oxygenase that forms prostaglandins. (1976) (66)
Properties of inositol polyphosphate 1-phosphatase. (1988) (65)
Relationships between platelets and coagulation factors in hemostasis. (1978) (65)
Disruption of the mouse inositol 1,3,4,5,6-pentakisphosphate 2-kinase gene, associated lethality, and tissue distribution of 2-kinase expression. (2005) (64)
Isolation of vitamin B12-binding proteins using affinity chromatography. II. Purification and properties of a human granulocyte vitamine B12-binding protein. (1972) (63)
Characterization of a cDNA encoding Arabidopsis thaliana inositol 1,3,4-trisphosphate 5/6-kinase. (1997) (62)
Specificity determinants in inositol polyphosphate synthesis: crystal structure of inositol 1,3,4-trisphosphate 5/6-kinase. (2005) (62)
The role of prostaglandins in platelet function. (1979) (61)
A role for thrombomodulin in the pathogenesis of thrombin-induced thromboembolism in mice (1988) (60)
Evidence for a single class of thrombin-binding sites of human platelets. (1976) (59)
The Properties of the Protein Tyrosine Phosphatase PTPMEG* (1996) (59)
Inositol polyphosphate 4-phosphatase B as a regulator of bone mass in mice and humans. (2011) (58)
Inositol Polyphosphate 4-Phosphatase Is Inactivated by Calpain-mediated Proteolysis in Stimulated Human Platelets* (1997) (58)
Cloning and expression of human 75-kDa inositol polyphosphate-5-phosphatase. (1991) (57)
The mRNA Export Factor Human Gle1 Interacts with the Nuclear Pore Complex Protein Nup155* (2004) (57)
Inositols do it all. (1996) (56)
The regulation of fatty acid biosynthesis in human skin fibroblasts. (1973) (56)
Uptake and subcellular distribution of [3H]arachidonic acid in murine fibrosarcoma cells measured by electron microscope autoradiography (1985) (56)
Fatty acid biosynthesis and the role of the acyl carrier protein. (1967) (55)
Glutathione synthesis in human erythrocytes. II. Purification and properties of the enzymes of glutathione biosynthesis. (1971) (55)
[6] Acyl carrier protein from Escherichia coli (1969) (53)
Human thrombomodulin is not an efficient inhibitor of the procoagulant activity of thrombin. (1985) (53)
Diverse proteins homologous to inositol monophosphatase (1991) (52)
Comparative effects of aspirin and diflunisal on prostaglandin synthetase from human platelets and sheep seminal vesicles. (1977) (51)
Inositol polyphosphate 4-phosphatase type I regulates cell growth downstream of transcription factor GATA-1. (2000) (50)
Isolation and structural characterization of the polypeptide subunits of membrane glycoprotein IIb-IIIa from human platelets. (1982) (50)
A role for thrombomodulin in the pathogenesis of thrombin-induced thromboembolism in mice. (1988) (49)
The regulation of fatty acid synthesis in human skin fibroblasts. Inhibition of fatty acid synthesis by free fatty acids. (1973) (49)
Activation of coagulation factor V by a platelet protease. (1982) (48)
The inositol polyphosphate 4-phosphatase forms a complex with phosphatidylinositol 3-kinase in human platelet cytosol. (1999) (48)
Bradykinin-stimulated release of arachidonate from phosphatidyl inositol in mouse fibrosarcoma cells. (1980) (48)
The perturbation of thrombin binding to human platelets by anions. (1975) (48)
Myotubularin-related protein (MTMR) 9 determines the enzymatic activity, substrate specificity, and role in autophagy of MTMR8 (2012) (47)
Pathway for the formation of D-3 phosphate containing inositol phospholipids in intact human platelets. (1990) (47)
Isolation and characterization of two 3-phosphatases that hydrolyze both phosphatidylinositol 3-phosphate and inositol 1,3-bisphosphate. (1991) (47)
The effects of thrombin on adenyl cyclase activity and a membrane protein from human platelets. (1972) (46)
THE EFFECTS OF THROMBIN ON PHYTOHEMAGGLUTININ RECEPTOR SITES IN HUMAN PLATELETS (1974) (46)
Acyl carrier protein. VII. The primary structure of the substrate-binding site. (1965) (46)
A mutant HSDM1C1 fibrosarcoma line selected for defective eicosanoid precursor uptake lacks arachidonate-specific acyl-CoA synthetase. (1984) (45)
Inositol cyclic triphosphate [inositol 1,2-(cyclic)-4,5-triphosphate] is formed upon thrombin stimulation of human platelets. (1986) (45)
Human coagulation factor Va is a cofactor for the activation of protein C. (1983) (44)
Neural tube defects in mice with reduced levels of inositol 1,3,4-trisphosphate 5/6-kinase (2009) (44)
Characterization of an adapter subunit to a phosphatidylinositol (3)P 3-phosphatase: Identification of a myotubularin-related protein lacking catalytic activity (2001) (43)
Crystal structure of inositol polyphosphate 1-phosphatase at 2.3-A resolution. (1994) (42)
The cDNA Cloning and Characterization of Inositol Polyphosphate 4-Phosphatase Type II EVIDENCE FOR CONSERVED ALTERNATIVE SPLICING IN THE 4-PHOSPHATASE FAMILY* (1997) (42)
MTMR9 Increases MTMR6 Enzyme Activity, Stability, and Role in Apoptosis* (2009) (41)
Isolation and heterologous expression of a cDNA encoding bovine inositol polyphosphate 1-phosphatase. (1990) (40)
Prostaglandins: Critical roles in pregnancy and colon cancer (1998) (39)
Editorial: Why aspirin? (1976) (38)
Phosphorylation of Platelet Pleckstrin Activates Inositol Polyphosphate 5-Phosphatase I* (1997) (37)
Inositol polyphosphate 1-phosphatase is present in the nucleus and inhibits DNA synthesis. (1994) (37)
ACYL CARRIER PROTEIN. 3. AN ENOYL HYDRASE SPECIFIC FOR ACYL CARRIER PROTEIN THIOESTERS. (1965) (37)
Fatty acid structural requirements for activity of arachidonoyl-CoA synthetase. (1984) (35)
Fatty acid biosynthesis in human leukocytes. (1967) (35)
Signaling Inositol Polyphosphate-5-phosphatase (1997) (33)
Phosphoinositide phosphatases and disease This work is supported by funds from the Howard Hughes Medical Institute (J.D.Y.), and from the National Institutes of Health HL-55672 (J.D.Y.) and HL-016634 (P.W.M.) Published, JLR Papers in Press, November 11, 2008. (2009) (33)
Increased Levels of Inositol Hexakisphosphate (InsP6) Protect HEK293 Cells from Tumor Necrosis Factor α- and Fas-induced Apoptosis* (2005) (33)
Effects of thrombomodulin and coagulation Factor Va-light chain on protein C activation in vitro. (1984) (32)
The effect of overexpression of the protein tyrosine phosphatase PTPMEG on cell growth and on colony formation in soft agar in COS-7 cells. (1996) (32)
[19] Human factor VII (1981) (32)
The binding of human and bovine thrombin to human platelets. (1976) (32)
Isolation of D-myo-inositol 1:2-cyclic phosphate 2-inositolphosphohydrolase from human placenta. (1986) (32)
Protein C inhibits endocytosis of thrombin−thrombomodulin complexes in A549 lung cancer cells and human umbilical vein endothelial cells (1987) (31)
Lipid metabolism in human platelets. II. De novo phospholipid synthesis and the effect of thrombin on the pattern of synthesis. (1969) (30)
The v-sis oncogene product but not platelet-derived growth factor (PDGF) a homodimers activate PDGF α and β receptors intracellularly and initiate cellular transformation (1992) (29)
RHC 80267 does not inhibit the diglyceride lipase pathway in intact platelets. (1983) (29)
Acyl Carrier Protein: Effects of Acetylation and Tryptic Hydrolysis on Function in Fatty Acid Synthesis (1968) (29)
The discovery of a 3-phosphomonoesterase that hydrolyzes phosphatidylinositol 3-phosphate in NIH 3T3 cells. (1989) (29)
Induction of the platelet release reaction by phytohemagglutinin. (1974) (26)
Human genetics. Bad blood by mutation. (1994) (26)
The isolation and characterization of inositol polyphosphate 4-phosphatase. (1990) (26)
Thrombin-stimulated immunoprecipitation of phosphatidylinositol 3-kinase from human platelets. (1990) (24)
An Entamoeba histolytica inositol 1,3,4-trisphosphate 5/6-kinase has a novel 3-kinase activity. (2000) (24)
The light chain of factor Va contains the activity of factor Va that accelerates protein C activation by thrombin. (1983) (24)
Transcription of thrombomodulin mRNA in mouse hemangioma cells is increased by cycloheximide and thrombin. (1989) (24)
Acetyl coenzyme A carboxylase. The effects of biotin deficiency on enzyme in rat liver and adipose tissue. (1970) (23)
Characterization and assay of diacylglycerol lipase from human platelets. (1982) (23)
Development and characterization of a tissue culture cell line with essential fatty acid deficiency. (1982) (22)
Diglyceride lipase: a pathway for arachidonate release from human platelets. (1980) (22)
Acyl Carrier Protein. VI. Purification and Properties of β-Ketoacyl Acyl Carrier Protein Synthetase* (1965) (22)
The role of inositol signaling in the control of apoptosis. (2008) (22)
A Novel Phosphatidylinositol-3,4,5-trisphosphate 5-Phosphatase Associates with the Interleukin-3 Receptor* (1996) (21)
The Biosynthesis of β-Hydroxy-β-methylglutaryl Coenzyme A in Yeast V. THE ROLE OF ACYL CARRIER PROTEIN (1966) (21)
Binding of the products of prothrombin activation to human platelets. (1975) (20)
Expression of inositol 1,3,4-trisphosphate 5/6-kinase (ITPK1) and its role in neural tube defects. (2010) (20)
Structure and function of the acyl carrier protein. (1966) (20)
Sequence of a cDNA for mouse thrombomodulin and comparison of the predicted mouse and human amino acid sequences. (1989) (19)
Pathway for the formation of D-3 phosphate containing inositol phospholipids in PDGF stimulated NIH 3T3 fibroblasts. (1991) (19)
Cloning, heterologous expression, and chromosomal localization of human inositol polyphosphate 1-phosphatase. (1993) (19)
The role of erythropoietin receptor tyrosine phosphorylation in erythropoietin-induced proliferation. (1997) (19)
Inositol 1,3,4-Trisphosphate 5/6-Kinase Inhibits Tumor Necrosis Factor-induced Apoptosis* (2003) (18)
Inositol polyphosphate multikinase regulates inositol 1,4,5,6-tetrakisphosphate. (2006) (18)
Acyl carrier protein. Structural requirements for function in fatty acid biosynthesis. (1967) (17)
The role of myotubularin-related phosphatases in the control of autophagy and programmed cell death. (2012) (17)
Cyclic hydrolase-transfected 3T3 cells have low levels of inositol 1,2-cyclic phosphate and reach confluence at low density. (1991) (16)
Uptake and release of arachidonate by platelets. (1983) (14)
Blasts from the past. (2004) (14)
[5] Mechanism of saturated fatty acid biosynthesis in Escherichia coli (1969) (13)
Regulation of inositol 1,3,4-trisphosphate 5/6-kinase (ITPK1) by reversible lysine acetylation (2012) (13)
The v-sis oncogene product but not platelet-derived growth factor (PDGF) A homodimers activate PDGF alpha and beta receptors intracellularly and initiate cellular transformation. (1992) (12)
Fraud in medical research. Presidential address delivered before the 74th annual meeting of the American Society for Clinical Investigation, Washington, DC, 8 May 1982. (1982) (12)
INO-4995 therapeutic efficacy is enhanced with repeat dosing in cystic fibrosis knockout mice and human epithelia. (2010) (12)
Crystallization and initial X-ray crystallographic characterization of recombinant bovine inositol polyphosphate 1-phosphatase produced in Spodoptera frugiperda cells. (1994) (11)
Protein C inhibits endocytosis of thrombin-thrombomodulin complexes in A549 lung cancer cells and human umbilical vein endothelial cells. (1987) (10)
THE MECHANISM OF FATTY ACID BIOSYNTHESIS AND THE INVOLVEMENT OF AN ACYL CARRIER PROTEIN (1965) (9)
CHAPTER 18 – Phosphatidylinositol Phospholipase C (1990) (8)
[9] β-Ketoacyl acyl carrier protein synthase (1969) (8)
[7] Acetyl-CoA acyl carrier protein transacylase (1969) (8)
Measurement of icosanoid precursor uptake and release by intact cells. (1987) (7)
A Discrete Signaling Function for an Inositol Pyrophosphate (2007) (7)
Mechanisms for Eicosanoid Precursor Uptake and Release by a Tissue Culture Cell Line (1985) (7)
The role of inositol polyphosphate 4-phosphatase 1 in platelet function using a weeble mouse model. (2011) (7)
Eicosadiynoic acid: a non-toxic inhibitor of multiple enzymatic steps in the production of icosanoids from arachidonic acid. (1987) (7)
Identification of a phosphodiesterase that converts inositol cyclic 1:2-phosphate to inositol 2-phosphate. (1992) (6)
of Platelet Prostaglandin Synthetase by Oral Aspirin (1978) (6)
[10] β-Ketoacyl acyl carrier protein reductase (1969) (6)
The relation of conductivity to the binding of thrombin to human platelets. (1978) (6)
Health, air pollution, and animal agriculture (2020) (5)
The Phosphatidylinositol Pathway of Platelets and Vascular Cells a (1991) (5)
Mammalian cells that express Bacillus cereus phosphatidylinositol-specific phospholipase C have increased levels of inositol cyclic 1:2-phosphate, inositol 1-phosphate, and inositol 2-phosphate. (1992) (5)
[11] β-Hydroxybutyryl acyl carrier protein dehydrase from Escherichia coli (1969) (5)
Use of vitamin B 12 in affinity chromatography. (1974) (5)
Erythrocyte glutathione synthesis in the neonate. (1974) (5)
Isolation of Vitamin B , ,-binding Proteins Using Affinity Chromatography (2002) (5)
Protein kinase C (PKC) phosphorylates human platelet inositol trisphosphate 5/sup +/-/-phosphomonoesterase (IP/sub 3/ 5'-p'tase) increasing phosphatase activity (1986) (5)
[Distribution of thrombomodulin in human tissues and characterization of thrombomodulin in plasma]. (1988) (5)
Inositol-1,2-cyclic-phosphate 2-inositolphosphohydrolase. Substrate specificity and regulation of activity by phospholipids, metal ion chelators, and inositol 2-phosphate. (1991) (4)
Phosphoinositide metabolism in human platelets. (1987) (4)
Complex Interaction between Factor Va‐Light Chain and Thrombomodulin in the Regulation of Protein C Activation a (1986) (4)
The 5-hydroxyl of myo-inositol is essential for uptake into HSDM1C1 mouse fibrosarcoma cells. (1985) (3)
An aspirin a day. (2014) (3)
SopB, a protein required for virulence of Salmonella dublin ,i s an inositol phosphate phosphatase (phosphatidylinositolycell signalingychloride channels) (1998) (3)
Isolation of 1-monomethylphosphoinositol 4,5-bisphosphate [a product of methanolysis of inositol 1,2-(cyclic)-4,5-trisphosphate] from Swiss mouse 3T3 cells. (1988) (2)
[8] Malonyl-CoA acyl carrier protein transacylase (1969) (2)
Synthesis of inositol 1,2-(cyclic)-4,5-trisphosphate. (1987) (2)
Pathways of phosphoinositide metabolism in human platelets. (1985) (2)
The role of phosphoinositides in cell physiology. (1986) (1)
The production of phosphoinositide-derived messenger molecules. (1986) (1)
Inositol 1,3,4-trisphosphate 5/6-kinase complexed Mg2+/ADP (2005) (1)
Plasma antithrombins and thrombin binding to platelets in plasma. (1979) (1)
Wandering through the Laboratory (2010) (1)
Generated by C-Terminal Truncation Multiple Forms of the SH2-Containing Inositol Phosphatase, SHIP, Are (2013) (0)
ANOFFICIAL JOURNAL ofte AMERICAN HEARTASSOCIATION (2017) (0)
Inositol 1,3,4-trisphosphate 5/6-Kinase in complex with Mg2+/AMP-PCP/Ins(1,3,4)P3 (2005) (0)
The Metabolism of Inositol Phosphates (1988) (0)
Prothrombin Activation on the platelet surface (1979) (0)
Isolation And Characterization Of Platelet Membrane Glycoprotein IIB-IIIa With A Monoclonal Antibody (1981) (0)
The George M. Kober Lecture: molecular mechanisms of intracellular signal transduction. (1991) (0)
Chemical messengers of the inflammatory process. Handbook of inflammation, volume 1 J. C. Houck, ed. Amsterdam, New York: Elsevier/North-Holland. (1979). 421 pp. $75.00 (1980) (0)
1997 PEDIATRIC ACADEMIC SOCIETIES ’ ANNUAL MEETING SPONSORED BY THE AMERICAN PEDIATRIC Socnrr S 0 cIE ’ rY FOR PEDIATRIC RESEARCH AND AMULATORY PEDIATRIC ASSOCIATION (2004) (0)
Isolation of 1-monomethylphosphoinositol 4 , 5-bisphosphate [ a product of methanolysis of inositol 1 , 2-( cyclic )-4 , 5-trisphosphate ] from Swiss mouse 3 T 3 cells ( inositol cyclic phosphates / signal transduction / inositol cyclic trisphosphate ) (0)
PHYTOHEMAGGLUTININ RECEPTOR SITES IN HUMAN PLATELETS (1974) (0)
Acetylation of prostaglandin synthase by aspirin ( platelets / seminal vesicles (0)
Reply from Wilson and Majerus (1986) (0)
EFFECT OF THROMBIN ON THE PATTERN OF SYNTHESIS NANCY (0)
Increased levels of inositol hexakisphosphate (InsP6) protect HEK293 cells from TNFα and Fas induced apoptosis (2005) (0)
The anticoagulant properties of thrombomodulin (1986) (0)
The Regulation of Fatty Acid Biosynthesis in Rat (2003) (0)
t of Arteries , Veins , Capillaries , and Lymphatics , and on Syncytiotrophoblast of Human Placenta (2003) (0)
PREPARATION OF ANTI-HUMAN THROMBOMODULIN ANTIBODIES AND THEIR APPLICATION FOR STUDY ON PLASMA THROMBOMODULIN (1987) (0)
Prostaglandins, icosanoids, leukotrienes, and other lipids (1987) (0)
Cardiovascular news (1999) (0)
ofte AMERICAN HEART ASSOCIATION NO . 3 1976 EDITORIAL Why Aspirin ? (0)
Phosphatidylinositol-4-phosphate 5-kinases synthesize two distinct signaling molecules from phosphatidylinositol 3-phosphate (1997) (0)
How does the brain function during starvation ? 1972 – 1977 (2004) (0)
Wandering through the laboratory. (2011) (0)
Interaction between human myotubularin proteins MTMR6 and MTMR9 (2006) (0)
Type 1 inositol polyphosphate-4-phosphatase influences growth of primary megakaryocytes and other cell types and is differentially expressed in the absence of GATA-1. (1999) (0)
The biosynthesis of beta-hydroxy-beta-methylglutaryl coenzyme A in yeast. V. The role of acyl carrier protein. (1966) (0)
IDENTIFICATION OF THE ENZYMES OF GLUTATHIONESYNTHESIS IN HEMOLYSATES (0)
Human coagulation factor Va is a c protein C (blood clotting/factor V/clotting inhibitors) (2016) (0)

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