Philip Quirke
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(Suggest an Edit or Addition)Philip Quirke's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Short-term endpoints of conventional versus laparoscopic-assisted surgery in patients with colorectal cancer (MRC CLASICC trial): multicentre, randomised controlled trial (2005) (2852)
- Summary of product characteristics (2016) (2018)
- LOCAL RECURRENCE OF RECTAL ADENOCARCINOMA DUE TO INADEQUATE SURGICAL RESECTION Histopathological Study of Lateral Tumour Spread and Surgical Excision (1986) (1891)
- Randomized trial of laparoscopic-assisted resection of colorectal carcinoma: 3-year results of the UK MRC CLASICC Trial Group. (2007) (1444)
- Preoperative radiotherapy versus selective postoperative chemoradiotherapy in patients with rectal cancer (MRC CR07 and NCIC-CTG C016): a multicentre, randomised trial (2009) (1327)
- Role of circumferential margin involvement in the local recurrence of rectal cancer (1994) (1018)
- Effect of the plane of surgery achieved on local recurrence in patients with operable rectal cancer: a prospective study using data from the MRC CR07 and NCIC-CTG CO16 randomised clinical trial (2009) (923)
- What is the role for the circumferential margin in the modern treatment of rectal cancer? (2008) (914)
- Five‐year follow‐up of the Medical Research Council CLASICC trial of laparoscopically assisted versus open surgery for colorectal cancer (2010) (909)
- Kirsten ras mutations in patients with colorectal cancer: the ‘RASCAL II’ study (2001) (873)
- Macroscopic evaluation of rectal cancer resection specimen: clinical significance of the pathologist in quality control. (2002) (843)
- Diagnostic accuracy of preoperative magnetic resonance imaging in predicting curative resection of rectal cancer: prospective observational study (2006) (791)
- Rates of Circumferential Resection Margin Involvement Vary Between Surgeons and Predict Outcomes in Rectal Cancer Surgery (2002) (638)
- Complete mesocolic excision with central vascular ligation produces an oncologically superior specimen compared with standard surgery for carcinoma of the colon. (2010) (625)
- Value of mismatch repair, KRAS, and BRAF mutations in predicting recurrence and benefits from chemotherapy in colorectal cancer. (2011) (616)
- Low rectal cancer: a call for a change of approach in abdominoperineal resection. (2005) (575)
- Long‐term follow‐up of the Medical Research Council CLASICC trial of conventional versus laparoscopically assisted resection in colorectal cancer (2013) (574)
- Recommendations for reporting tumor budding in colorectal cancer based on the International Tumor Budding Consensus Conference (ITBCC) 2016 (2017) (561)
- KRAS and BRAF mutations in advanced colorectal cancer are associated with poor prognosis but do not preclude benefit from oxaliplatin or irinotecan: results from the MRC FOCUS trial. (2009) (558)
- WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors. (1998) (541)
- Preoperative High-resolution Magnetic Resonance Imaging Can Identify Good Prognosis Stage I, II, and III Rectal Cancer Best Managed by Surgery Alone: A Prospective, Multicenter, European Study (2011) (530)
- Magnetic resonance imaging-detected tumor response for locally advanced rectal cancer predicts survival outcomes: MERCURY experience. (2011) (524)
- Mismatch Repair Status and BRAF Mutation Status in Metastatic Colorectal Cancer Patients: A Pooled Analysis of the CAIRO, CAIRO2, COIN, and FOCUS Studies (2014) (499)
- European guidelines for quality assurance in colorectal cancer screening and diagnosis: Overview and introduction to the full Supplement publication (2012) (469)
- The Modern Abdominoperineal Excision: The Next Challenge After Total Mesorectal Excision (2005) (438)
- Extramural depth of tumor invasion at thin-section MR in patients with rectal cancer: results of the MERCURY study. (2007) (438)
- Preoperative magnetic resonance imaging assessment of circumferential resection margin predicts disease-free survival and local recurrence: 5-year follow-up results of the MERCURY study. (2014) (430)
- PCR: a practical approach. (1991) (429)
- Mutational signature in colorectal cancer caused by genotoxic pks+E. coli (2020) (426)
- EURECCA colorectal: multidisciplinary management: European consensus conference colon & rectum. (2014) (395)
- Evidence of the oncologic superiority of cylindrical abdominoperineal excision for low rectal cancer. (2008) (387)
- Pathology grading of colon cancer surgical resection and its association with survival: a retrospective observational study. (2008) (370)
- Localised Colon Cancer: ESMO Clinical Practice Guidelines for Diagnosis, Treatment and Follow-up. (2020) (370)
- Multicentre experience with extralevator abdominoperineal excision for low rectal cancer (2010) (368)
- Bladder and sexual function following resection for rectal cancer in a randomized clinical trial of laparoscopic versus open technique (2005) (367)
- Validation study of a quantitative multigene reverse transcriptase-polymerase chain reaction assay for assessment of recurrence risk in patients with stage II colon cancer. (2011) (349)
- Panitumumab and irinotecan versus irinotecan alone for patients with KRAS wild-type, fluorouracil-resistant advanced colorectal cancer (PICCOLO): a prospectively stratified randomised trial (2013) (349)
- Understanding optimal colonic cancer surgery: comparison of Japanese D3 resection and European complete mesocolic excision with central vascular ligation. (2012) (344)
- Total mesorectal excision and local recurrence: A study of tumour spread in the mesorectum distal to rectal cancer (1995) (326)
- Surgical management and outcomes of colorectal cancer liver metastases (2010) (309)
- Unlocking the archive – gene expression in paraffin‐embedded tissue (2001) (299)
- Tissue extraction of DNA and RNA and analysis by the polymerase chain reaction. (1990) (295)
- A randomised trial of the effect of omega-3 polyunsaturated fatty acid supplements on the human intestinal microbiota (2017) (292)
- Multidisciplinary Rectal Cancer Management: 2nd European Rectal Cancer Consensus Conference (EURECA-CC2). (2009) (287)
- Predictive biomarkers of chemotherapy efficacy in colorectal cancer: results from the UK MRC FOCUS trial. (2008) (281)
- Thirty-day postoperative mortality after colorectal cancer surgery in England (2011) (279)
- The prediction of local recurrence in rectal adenocarcinoma by histopathological examination (1988) (277)
- An international, multicentre, prospective, randomised, controlled, unblinded, parallel-group trial of robotic-assisted versus standard laparoscopic surgery for the curative treatment of rectal cancer (2012) (262)
- Prognostic value of p53 overexpression and c-Ki-ras gene mutations in colorectal cancer. (1993) (258)
- Circumferential margin involvement after mesorectal excision of rectal cancer with curative intent (1998) (242)
- Prospective Validation of a Low Rectal Cancer Magnetic Resonance Imaging Staging System and Development of a Local Recurrence Risk Stratification Model: The MERCURY II Study (2016) (238)
- Identification of Helicobacter pylori DNA in the mouths and stomachs of patients with gastritis using PCR. (1993) (238)
- KRAS mutation testing for predicting response to anti-EGFR therapy for colorectal carcinoma: proposal for an European quality assurance program (2008) (234)
- Impact of short-course preoperative radiotherapy for rectal cancer on patients' quality of life: data from the Medical Research Council CR07/National Cancer Institute of Canada Clinical Trials Group C016 randomized clinical trial. (2010) (207)
- DNA markers predicting benefit from adjuvant fluorouracil in patients with colon cancer: a molecular study (2002) (200)
- Rapid detection of allele loss in colorectal tumours using microsatellites and fluorescent DNA technology. (1993) (198)
- Cell proliferation in Helicobacter pylori associated gastritis and the effect of eradication therapy. (1995) (197)
- Choice of management strategy for colorectal cancer based on a diagnostic immunohistochemical test for defective mismatch repair (1999) (196)
- DNA fingerprinting from single cells (1997) (192)
- A uniform residual tumor (R) classification (2009) (183)
- The rationale behind complete mesocolic excision (CME) and a central vascular ligation for colon cancer in open and laparoscopic surgery (2014) (181)
- Chronicle: results of a randomised phase III trial in locally advanced rectal cancer after neoadjuvant chemoradiation randomising postoperative adjuvant capecitabine plus oxaliplatin (XELOX) versus control. (2014) (180)
- Unacceptable variation in abdominoperineal excision rates for rectal cancer: time to intervene? (2008) (177)
- Multicenter randomized controlled trial of conventional versus laparoscopic surgery for colorectal cancer within an enhanced recovery programme: EnROL. (2014) (176)
- Allelic drop-out and preferential amplification in single cells and human blastomeres: implications for preimplantation diagnosis of sex and cystic fibrosis. (1995) (175)
- Overexpression of HER2/neu in solid tumours: an immunohistochemical survey (2001) (174)
- Comparison of Magnetic Resonance Imaging and Histopathological Response to Chemoradiotherapy in Locally Advanced Rectal Cancer (2012) (173)
- Prognostic significance of DNA aneuploidy and cell proliferation in rectal adenocarcinomas (1987) (172)
- p53 in colorectal cancer: clinicopathological correlation and prognostic significance (1991) (172)
- Circumferential resection margin involvement: an independent predictor of survival following surgery for oesophageal cancer (2001) (169)
- Frequency of allele loss of DCC, p53, RBI, WT1, NF1, NM23 and APC/MCC in colorectal cancer assayed by fluorescent multiplex polymerase chain reaction. (1994) (166)
- Clinical-grade Detection of Microsatellite Instability in Colorectal Tumors by Deep Learning. (2020) (165)
- HER2 overexpression and amplification as a potential therapeutic target in colorectal cancer: analysis of 3256 patients enrolled in the QUASAR, FOCUS and PICCOLO colorectal cancer trials (2016) (165)
- The proportion of tumour cells is an independent predictor for survival in colorectal cancer patients (2010) (161)
- Has the new TNM classification for colorectal cancer improved care? (2012) (159)
- One millimetre is the safe cut‐off for magnetic resonance imaging prediction of surgical margin status in rectal cancer (2011) (159)
- High grade dysplasia of the gastric mucosa: a marker for gastric carcinoma. (1990) (158)
- The future of the TNM staging system in colorectal cancer: time for a debate? (2007) (151)
- PCR identification of Helicobacter pylori in faeces from gastritis patients (1993) (146)
- Training and quality assurance for rectal cancer: 20 years of data is enough. (2003) (146)
- Colorectal tumour deposits in the mesorectum and pericolon; a critical review (2007) (145)
- Colour Normalisation in Digital Histopathology Images (2009) (142)
- KRAS mutation testing for predicting response to anti-EGFR therapy for colorectal carcinoma: proposal for an European quality assurance program (2008) (140)
- Toward routine use of 3D histopathology as a research tool. (2012) (139)
- Methylation and colorectal cancer (2001) (138)
- Loss of expression of oestrogen receptor beta in colon cancer and its association with Dukes' staging. (2005) (138)
- Who to treat with adjuvant therapy in Dukes B/stage II colorectal cancer? The need for high quality pathology (2007) (136)
- Reporting colorectal cancer (2007) (136)
- Tumor Deposits in Colorectal Cancer: Improving the Value of Modern Staging-A Systematic Review and Meta-Analysis. (2017) (134)
- Identifying stage III colorectal cancer patients: the influence of the patient, surgeon, and pathologist. (2007) (132)
- Quality assurance in pathology in colorectal cancer screening and diagnosis—European recommendations (2010) (131)
- Early gastric cancer: 46 cases treated in one surgical department. (1992) (131)
- Endoluminal ultrasound and computed tomography in the staging of rectal cancer (1988) (130)
- Achaete-scute like 2 (ascl2) is a target of Wnt signalling and is upregulated in intestinal neoplasia (2006) (130)
- Association of molecular markers with toxicity outcomes in a randomized trial of chemotherapy for advanced colorectal cancer: the FOCUS trial. (2009) (130)
- A quantitative multigene RT-PCR assay for prediction of recurrence in stage II colon cancer: Selection of the genes in four large studies and results of the independent, prospectively designed QUASAR validation study. (2009) (129)
- Patient factors influencing conversion from laparoscopically assisted to open surgery for colorectal cancer (2007) (127)
- Early rectal cancer: the European Association for Endoscopic Surgery (EAES) clinical consensus conference (2015) (124)
- Lymph nodes, tumor deposits, and TNM: are we getting better? (2011) (123)
- Investigating the poor outcomes of BRAF-mutant advanced colorectal cancer: analysis from 2530 patients in randomised clinical trials (2016) (119)
- Short-term costs of conventional vs laparoscopic assisted surgery in patients with colorectal cancer (MRC CLASICC trial) (2006) (118)
- Helicobacter pylori infection and dental care. (1995) (116)
- Heterogeneity of colorectal adenocarcinomas evaluated by flow cytometry and histopathology. (1985) (115)
- Patients With Low Rectal Cancer Treated by Abdominoperineal Excision Have Worse Tumors and Higher Involved Margin Rates Compared With Patients Treated by Anterior Resection (2010) (113)
- EphB2 is a Prognostic Factor in Colorectal Cancer (2005) (111)
- MRI staging of low rectal cancer (2009) (110)
- Relevance of magnetic resonance imaging‐detected pelvic sidewall lymph node involvement in rectal cancer (2011) (109)
- Microsatellite instability in colorectal cancer: improved assessment using fluorescent polymerase chain reaction. (1995) (106)
- Mycobacterium paratuberculosis DNA not detected in Crohn's disease tissue by fluorescent polymerase chain reaction. (1995) (104)
- Significance of circumferential resection margin involvement after oesophagectomy for cancer (1993) (104)
- Systemic neutrophil-to-lymphocyte ratio in colorectal cancer: the relationship to patient survival, tumour biology and local lymphocytic response to tumour (2015) (102)
- Improving the Quality of Colon Cancer Surgery Through a Surgical Education Program (2010) (99)
- A systematic review of cancer related patient outcomes after anterior resection and abdominoperineal excision for rectal cancer in the total mesorectal excision era. (2011) (97)
- Prediction of the response of colorectal cancer to systemic therapy. (2002) (97)
- In situ validation of an intestinal stem cell signature in colorectal cancer (2012) (96)
- DNA aneuploidy in ulcerative colitis. (1986) (95)
- Flow cytometry: Methodology and applications in pathology (1986) (92)
- DNA aneuploidy in colorectal adenomas. (1986) (92)
- Image-based consensus molecular subtype (imCMS) classification of colorectal cancer using deep learning (2020) (91)
- Intra-tumoral Heterogeneity of KRAS and BRAF Mutation Status in Patients with Advanced Colorectal Cancer (aCRC) and Cost-Effectiveness of Multiple Sample Testing (2011) (91)
- EURECCA colorectal: multidisciplinary mission statement on better care for patients with colon and rectal cancer in Europe. (2013) (90)
- Accuracy of radiological staging in identifying high‐risk colon cancer patients suitable for neoadjuvant chemotherapy: a multicentre experience (2012) (90)
- A Flow Cytometric, Clinical, and Histological Study of Stromal Neoplasms of the Gastrointestinal Tract (1992) (88)
- Routine short course pre-op radiotherapy or selective post-op chemoradiotherapy for resectable rectal cancer? Preliminary results of the MRC CR07 randomised trial. (2006) (87)
- Parathyroid hormone-related peptide in normal human fetal development. (1990) (86)
- A retrospective observational study examining the characteristics and outcomes of tumours diagnosed within and without of the English NHS Bowel Cancer Screening Programme (2012) (86)
- c-Ki-ras gene mutations in dysplasia and carcinomas complicating ulcerative colitis. (1991) (85)
- Cross-laboratory validation of the OncoScan® FFPE Assay, a multiplex tool for whole genome tumour profiling (2015) (85)
- Kinetic and Physical Studies of Cell Death Induced By Chemotherapeutic Agents Or Hyperthermia (1986) (82)
- Expression of DNA Double-Strand Break Repair Proteins ATM and BRCA1 Predicts Survival in Colorectal Cancer (2006) (82)
- Can we Save the rectum by watchful waiting or TransAnal microsurgery following (chemo) Radiotherapy versus Total mesorectal excision for early REctal Cancer (STAR-TREC study)?: protocol for a multicentre, randomised feasibility study (2017) (80)
- Pattern of expression of c-erbB-2 oncoprotein in human fetuses. (1989) (79)
- Molecular pathology of colorectal cancer. (1997) (79)
- DETECTION OF MEASLES VIRUS RNA IN PARAFFIN-EMBEDDED TISSUE (1989) (79)
- MRI assessment of the bony pelvis may help predict resectability of rectal cancer (2005) (76)
- Combined Epiregulin and Amphiregulin Expression Levels as a Predictive Biomarker for Panitumumab Therapy Benefit or Lack of Benefit in Patients With RAS Wild-Type Advanced Colorectal Cancer. (2016) (76)
- Capecitabine, oxaliplatin, radiotherapy, and excision (CORE) in patients with MRI-defined locally advanced rectal adenocarcinoma: Results of an international multicenter phase II study. (2006) (75)
- Fixation and Spread of Somatic Mutations in Adult Human Colonic Epithelium (2018) (74)
- p53 in colorectal cancer: clinicopathological correlation and prognostic significance. (1991) (72)
- Defining the surgical planes on MRI improves surgery for cancer of the low rectum. (2009) (71)
- IntAct: intra‐operative fluorescence angiography to prevent anastomotic leak in rectal cancer surgery: a randomized controlled trial (2018) (71)
- The validity of the Royal College of Pathologists’ colorectal cancer minimum dataset within a population (2007) (71)
- Is DNA aneuploidy a good prognostic indicator in patients with advanced colorectal cancer? (1986) (70)
- Quality of Surgery for Stage III Colon Cancer: Comparison Between England, Germany, and Japan (2014) (69)
- Simultaneous DNA 'fingerprinting', diagnosis of sex and single-gene defect status from single cells. (1995) (69)
- Cell proliferation in the gastric corpus in Helicobacter pylori associated gastritis and after gastric resection. (1995) (69)
- Pre‐operative staging of rectal neoplasm and its impact on clinical management (1985) (69)
- Chronicle: results of a randomised phase III trial in locally advanced rectal cancer after neoadjuvant chemoradiation randomising postoperative adjuvant capecitabine plus oxaliplatin (XELOX) versus control. (2014) (68)
- c-erbB-2/c-erbA co-amplification indicative of lymph node metastasis, and c-myc amplification of high tumour grade, in human breast carcinoma. (1989) (68)
- Silver‐stained structures (AgNORs), their dependence on tissue fixation and absence of prognostic relevance in rectal adenocarcinoma (1989) (68)
- Focus on Extralevator Perineal Dissection in Supine Position for Low Rectal Cancer Has Led to Better Quality of Surgery and Oncologic Outcome (2012) (68)
- Viewing apoptosis through a ‘TUNEL’ (2001) (68)
- Comparison of labelling by bromodeoxyuridine, MIB-1, and proliferating cell nuclear antigen in gastric mucosal biopsy specimens. (1994) (66)
- European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender. (2020) (65)
- Radical surgery versus organ preservation via short-course radiotherapy followed by transanal endoscopic microsurgery for early-stage rectal cancer (TREC): a randomised, open-label feasibility study (2020) (64)
- High-Resolution Array Comparative Genomic Hybridization in Sporadic and Celiac Disease–Related Small Bowel Adenocarcinomas (2010) (64)
- Should the Benefit of Adjuvant Chemotherapy in Colon Cancer Be Re-Evaluated? (2016) (62)
- The Pathologist’s Role in the Assessment of Local Recurrence in Rectal Carcinoma (1992) (62)
- European guidelines for quality assurance in colorectal cancer screening and diagnosis. First Edition – Quality assurance in pathology in colorectal cancer screening and diagnosis (2012) (62)
- The English National Low Rectal Cancer Development Programme: key messages and future perspectives (2014) (60)
- Diagnosis of molar pregnancy and persistent trophoblastic disease by flow cytometry. (1987) (59)
- Cost effectiveness of antenatal screening for cystic fibrosis (1995) (59)
- The multidisciplinary rectal cancer treatment: main convergences, controversial aspects and investigational areas which support the need for an European Consensus. (2005) (57)
- p53 expression and K-ras mutation in colorectal adenomas. (1993) (57)
- Parathyroid hormone‐related peptide: Expression in fetal and neonatal development (1992) (57)
- MLH1 −93G>A promoter polymorphism and risk of mismatch repair deficient colorectal cancer (2008) (57)
- Can a Novel MRI Staging System for Low Rectal Cancer Aid Surgical Planning? (2011) (56)
- Area of Submucosal Invasion and Width of Invasion Predicts Lymph Node Metastasis in pT1 Colorectal Cancers (2015) (56)
- Accurately Identifying Low‐Allelic Fraction Variants in Single Samples with Next‐Generation Sequencing: Applications in Tumor Subclone Resolution (2013) (55)
- Mesorectal fascia instead of circumferential resection margin in preoperative staging of rectal cancer. (2011) (55)
- The role of microsatellite instability in gastric carcinoma (1998) (55)
- Wide Variation in the Use of Radiotherapy in the Management of Surgically Treated Rectal Cancer Across the English National Health Service (2016) (54)
- Cancer’s craving for sugar: an opportunity for clinical exploitation (2009) (54)
- Mycobacterium avium subspecies paratuberculosis is a cause of Crohn's disease (2001) (54)
- Multiple genetic diagnoses from single cells using multiplex PCR: reliability and allele dropout (1998) (53)
- Helicobacter gastritis and intestinal metaplasia in a gastric cancer family (1990) (53)
- Evidence‐based medicine: the time has come to set standards for staging (2010) (52)
- Virtual reality Powerwall versus conventional microscope for viewing pathology slides: an experimental comparison (2009) (52)
- Voyaging by canoe and computer: experiments in the settlement of the Pacific Ocean (1990) (52)
- Comparison of triplicated (S) and quadruplicated (W) pelvic ileal reservoirs. Studies on manovolumetry, fecal bacteriology, fecal volatile fatty acids, mucosal morphology, and functional results. (1992) (51)
- Flow cytofluorometric evidence for the differential radioresponsiveness of aneuploid and diploid cervix tumours. (1987) (51)
- DNA content and prognosis of non-Hodgkin's lymphoma. (1986) (50)
- European guidelines for quality assurance in colorectal cancer screening and diagnosis. First Edition – Annotations of colorectal lesions (2012) (50)
- Prognostic significance of microsatellite instability in patients with gastric carcinoma. (1997) (49)
- A pictorial description of extralevator abdominoperineal excision for low rectal cancer (2012) (49)
- Prenatal detection of trisomy 21 and 18 from amniotic fluid by quantitative fluorescent polymerase chain reaction. (1998) (48)
- Defective hMSH2/hMLH1 protein expression is seen infrequently in ulcerative colitis associated colorectal cancers (2000) (48)
- Local recurrence after rectal cancer resection is strongly related to the plane of surgical dissection and is further reduced by pre-operative short course radiotherapy. Preliminary results of the Medical Research Council (MRC) CR07 trial. (2006) (48)
- Molecular pathology of gastric carcinoma: progress and prospects. (1992) (48)
- Prognostic indicators in centroblastic-centrocytic lymphoma. (1988) (47)
- Candidate driver genes in focal chromosomal aberrations of stage II colon cancer (2010) (46)
- Deletion of chromosome 4q predicts outcome in Stage II colon cancer patients (2011) (46)
- Limitations of Existing Systems of Staging for Rectal Cancer: The Forgotten Margin (1997) (46)
- Cross-platform array comparative genomic hybridization meta-analysis separates hematopoietic and mesenchymal from epithelial tumors (2007) (45)
- A robust multiplex immunofluorescence and digital pathology workflow for the characterisation of the tumour immune microenvironment (2020) (45)
- Evaluation of the role of pre‐operative magnetic resonance imaging in the management of rectal cancer (2001) (44)
- Prognosis and response to therapy in colorectal cancer. (2002) (44)
- Tracking with virtual slides: a tool to study diagnostic error in histopathology (2009) (44)
- Morphometric analysis and lymph node yield in laparoscopic complete mesocolic excision performed by supervised trainees (2014) (44)
- Expression of the CUB domain containing protein 1 (CDCP1) gene in colorectal tumour cells (2007) (44)
- Quantitative analysis of colorectal tissue microarrays by immunofluorescence and in situ hybridization (2003) (43)
- Assessing the relative costs of standard open surgery and laparoscopic surgery in colorectal cancer in a randomised controlled trial in the United Kingdom. (2000) (43)
- Development and validation of deep learning classifiers to detect Epstein-Barr virus and microsatellite instability status in gastric cancer: a retrospective multicentre cohort study (2021) (42)
- Magnetic resonance imaging‐detected lymph nodes close to the mesorectal fascia are rarely a cause of margin involvement after total mesorectal excision (2010) (42)
- Virtual reality microscope versus conventional microscope regarding time to diagnosis: an experimental study (2013) (41)
- Early mortality from colorectal cancer in England: a retrospective observational study of the factors associated with death in the first year after diagnosis (2013) (41)
- Acute pouchitis and deficiencies of fuel (1995) (41)
- HELICOBACTER PYLORI INFECTION AND GASTRIC CANCER (1996) (40)
- RAPID SCREENING FOR ΔF508 DELETION IN CYSTIC FIBROSIS (1989) (39)
- EnROL: A multicentre randomised trial of conventional versus laparoscopic surgery for colorectal cancer within an enhanced recovery programme (2012) (39)
- Feasibility of family based screening for colorectal neoplasia: experience in one general surgical practice. (1993) (39)
- Direct multiplex amplification of DNA from a formalin fixed, paraffin wax embedded tissue section (2000) (39)
- Correlation between epithelial cell proliferation and histological grading in gastric mucosa. (1999) (39)
- Outcome measures in multimodal rectal cancer trials. (2020) (39)
- Inhibition of EGFR, HER2, and HER3 signalling in patients with colorectal cancer wild-type for BRAF, PIK3CA, KRAS, and NRAS (FOCUS4-D): a phase 2–3 randomised trial (2017) (39)
- Experimental models of colorectal cancer (1998) (38)
- Immune status is prognostic for poor survival in colorectal cancer patients and is associated with tumour hypoxia (2020) (38)
- Clarifying the TNM staging of rectal cancer in the context of modern imaging and neo‐adjuvant treatment: ‘y’‘u’ and ‘p’ need ‘mr’ and ‘ct’ (2008) (38)
- Rapid Trisomy Diagnosis (21, 18, and 13) Using Fluorescent PCR and Short Tandem Repeats: Applications for Prenatal Diagnosis and Preimplantation Genetic Diagnosis (1998) (38)
- Comparison of histopathological and flow cytometric parameters in prediction of prognosis in gastric cancer (1989) (37)
- Population-based study of laparoscopic colorectal cancer surgery 2006–2008 (2013) (37)
- Molecular biology of colorectal neoplasia. (1993) (37)
- Swarm learning for decentralized artificial intelligence in cancer histopathology (2021) (37)
- Small bowel adenocarcinoma copy number profiles are more closely related to colorectal than to gastric cancers. (2012) (37)
- Lymphatic vessel distribution in the mucosa and submucosa and potential implications for T1 colorectal tumors. (2011) (36)
- Clinicopathological, genomic and immunological factors in colorectal cancer prognosis (2018) (36)
- Carcinoma of the ileostomy in a patient with familial adenomatous polyposis (1988) (36)
- Fluorescent polymerase chain reaction: Part I. A new method allowing genetic diagnosis and DNA fingerprinting of single cells. (1996) (35)
- Assessment of microsatellite alterations in young patients with gastric adenocarcinoma (1997) (35)
- Fluorescent PCR: A new technique for PGD of sex and single-gene defects (1996) (34)
- Whole mount microscopic sections reveal that Denonvilliers' fascia is one entity and adherent to the mesorectal fascia; implications for the anterior plane in total mesorectal excision? (2015) (34)
- A retrospective observational study of the relationship between family history and survival from colorectal cancer (2013) (33)
- Standardised reports with a template format are superior to free text reports: the case for rectal cancer reporting in clinical practice (2019) (33)
- Sensitive, Simultaneous Quantitation of Two Unlabeled DNA Targets Using a Magnetic Nanoparticle–Enzyme Sandwich Assay (2013) (33)
- Abnormal Intestinal Permeability (1987) (33)
- Pathologic Processing of the Total Mesorectal Excision (2015) (32)
- MRI Predictive Factors for Long-Term Outcomes of Low Rectal Tumours (2011) (32)
- Weakly supervised annotation‐free cancer detection and prediction of genotype in routine histopathology (2021) (32)
- 6003 The correlation between Topoisomerase-I (Topo1) expression and outcome of treatment with capecitabine and irinotecan in advanced colorectal cancer (ACC) patients (pts) treated in the CAIRO study of the Dutch Colorectal Cancer Group (DCCG) (2009) (31)
- KRAS mutation analysis on low percentage of colon cancer cells: the importance of quality assurance (2012) (31)
- A feasibility study testing four hypotheses with phase II outcomes in advanced colorectal cancer (MRC FOCUS3): a model for randomised controlled trials in the era of personalised medicine? (2014) (30)
- DNA Methylation, a Biomarker for Colorectal Cancer (2003) (30)
- Deep learning detects genetic alterations in cancer histology generated by adversarial networks (2021) (30)
- Inhibition of WEE1 Is Effective in TP53- and RAS-Mutant Metastatic Colorectal Cancer: A Randomized Trial (FOCUS4-C) Comparing Adavosertib (AZD1775) With Active Monitoring (2021) (30)
- Modern Management of Colorectal Cancer — A Pathologist's View (2003) (30)
- Goseki grading in gastric cancer: comparison with existing systems of grading and its reproducibility (1994) (30)
- Comparison of treatment and outcome information between a clinical trial and the National Cancer Data Repository (2011) (30)
- Antagonist. Mycobacterium avium subspecies paratuberculosis is a cause of Crohn's disease. (2001) (29)
- Major histocompatibility complex class II antigen expression in B and T cell non-Hodgkin's lymphoma. (1987) (29)
- "Let my laptop lead the way": a Middle Eastern study (2002) (29)
- Clinical Trial of Oral Nelfinavir before and during Radiation Therapy for Advanced Rectal Cancer (2016) (29)
- Addition of panitumumab to irinotecan: Results of PICCOLO, a randomized controlled trial in advanced colorectal cancer (aCRC). (2011) (29)
- Annex to Quirke et al. Quality assurance in pathology in colorectal cancer screening and diagnosis: annotations of colorectal lesions (2010) (29)
- A retrospective observational study of length of stay in hospital after colorectal cancer surgery in England (1998–2010) (2016) (28)
- Artificial intelligence for detection of microsatellite instability in colorectal cancer—a multicentric analysis of a pre-screening tool for clinical application (2022) (28)
- Robotic-assisted surgery compared with laparoscopic resection surgery for rectal cancer: the ROLARR RCT (2019) (28)
- Chromosome 5q Loss in Colorectal Flat Adenomas (2012) (28)
- Bevacizumab and Combination Chemotherapy in rectal cancer Until Surgery (BACCHUS): a phase II, multicentre, open-label, randomised study of neoadjuvant chemotherapy alone in patients with high-risk cancer of the rectum (2015) (28)
- Implementation of complete mesocolic excision at a university hospital in Denmark: An audit of consecutive, prospectively collected colon cancer specimens. (2014) (26)
- Internal anal sphincter nerves – a macroanatomical and microscopic description of the extrinsic autonomic nerve supply of the internal anal sphincter (2018) (26)
- Understanding the surgical pitfalls in total mesorectal excision: Investigating the histology of the perirectal fascia and the pelvic autonomic nerves. (2015) (25)
- Parathyroid hormone-related peptide in the human fetal uro-genital tract (1990) (25)
- T3+ and T4 Rectal Cancer Patients Seem to Benefit From the Addition of Oxaliplatin to the Neoadjuvant Chemoradiation Regimen (2012) (25)
- Growth factor expression during rat development: a comparison of TGF-beta 3, TGF-alpha, bFGF, PDGF and PDGF-R. (1993) (24)
- Adenoma screening and colorectal cancer. (1991) (24)
- Colorectal cancer reporting: are we failing the patient? (1997) (24)
- A prospective phase II study of pre-operative chemotherapy then short-course radiotherapy for high risk rectal cancer: COPERNICUS (2018) (24)
- Pathology of colorectal cancer. (2007) (24)
- Rapid genetic diagnosis at 7-9 weeks gestation: diagnosis of sex, single gene defects and DNA fingerprint from coelomic samples. (1996) (24)
- Preoperative chemoradiation with capecitabine, irinotecan and cetuximab in rectal cancer: significance of pre-treatment and post-resection RAS mutations (2017) (24)
- Mesocolic plane surgery: an old but forgotten technique? (2009) (24)
- Significant Individual Variation Between Pathologists in the Evaluation of Colon Cancer Specimens After Complete Mesocolic Excision (2016) (23)
- TmaDB: a repository for tissue microarray data (2005) (23)
- In situ hybridisation for the identification of Helicobacter pylori in paraffin wax embedded tissue. (1994) (23)
- Revised staging: is it really better, or do we not know? (2010) (23)
- Correlation of morphology, immunophenotype, and flow cytometry with remission induction and survival in high grade non‐Hodgkin's lymphoma (1989) (23)
- Pre-trial inter-laboratory analytical validation of the FOCUS4 personalised therapy trial (2015) (22)
- Histopathological Work-Up of Resection Specimens, Local Excisions and Biopsies in Colorectal Cancer (2012) (22)
- Same day diagnosis of Down's syndrome and sex in single cells using multiplex fluorescent PCR. (1998) (22)
- The new biology: histopathology (1999) (21)
- Association of Tumor HER3 Messenger RNA Expression With Panitumumab Efficacy in Advanced Colorectal Cancer (2017) (21)
- KRAS and BRAF mutations in Nigerian colorectal cancers. (2012) (21)
- Role of the oxidative DNA damage repair gene OGG1 in colorectal tumorigenesis. (2013) (21)
- Hodgkin's disease: a flow cytometric study. (1988) (21)
- The Design and Evaluation of Interfaces for Navigating Gigapixel Images in Digital Pathology (2016) (21)
- EURECCA consensus conference highlights about colorectal cancer clinical management: the pathologists expert review (2014) (21)
- Comprehensive Mutation Analysis in Colorectal Flat Adenomas (2012) (21)
- Deep learning identifies inflamed fat as a risk factor for lymph node metastasis in early colorectal cancer (2021) (21)
- Severe Symptomatic Hypoglycaemia Due to Quinine Therapy (1986) (20)
- A comparison of microsatellite instability in early onset gastric carcinomas from relatively low and high incidence European populations (2000) (20)
- Genes mediating programmed cell death: an immunohistochemical study of bcl-2, c-myc and p53 expression in colorectal neoplasia (1996) (20)
- A Search for Candidate Viruses in Type 1 Diabetic Pancreas Using the Polymerase Chain Reaction (1994) (20)
- Standards and datasets for reporting cancers Dataset for histopathological reporting of colorectal cancer December 2017 (2018) (20)
- Intratumoral stromal morphometry predicts disease recurrence but not response to 5‐fluorouracil—results from the QUASAR trial of colorectal cancer (2018) (20)
- An investigation of different methods of cell cycle analysis by flow cytometry in rectal cancer. (1992) (20)
- European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender. (2021) (20)
- BACCHUS: A randomised non-comparative phase II study of neoadjuvant chemotherapy (NACT) in patients with locally advanced rectal cancer (LARC) (2018) (20)
- Challenging diagnostic issues in adenomatous polyps with epithelial misplacement in bowel cancer screening: 5 years’ experience of the Bowel Cancer Screening Programme Expert Board (2017) (20)
- Biology and genetics of colorectal cancer. (2001) (20)
- Quantitation by flow cytofluorometry of response of tumours of the uterine cervix to radiotherapy. (1985) (19)
- The colorectal cancer-associated faecal microbiome of developing countries resembles that of developed countries (2021) (19)
- Performance and interaction behaviour during visual search on large, high-resolution displays (2015) (19)
- Expression of the 17-1A antigen in gastric and gastro-oesophageal junction adenocarcinomas: a potential immunotherapeutic target? (1999) (19)
- Low abdominoperineal excision rates are associated with high‐workload surgeons and lower tumour height. Is further specialization needed? (2011) (18)
- Diagnosis of complete molar pregnancy by microsatellites in archival material. (1993) (18)
- Ischaemic proctitis and adventitial fibromuscular dysplasia of the superior rectal artery (1984) (18)
- A histologic and flow cytometric study of Kaposi's sarcoma (1992) (18)
- Flow cytometry of normal, hyperplastic, and malignant human endometrium. A study of ploidy and proliferative indices including comparison with in vitro S-phase labeling. (1989) (18)
- Flow cytometry in persistent trophoblastic disease. (1988) (18)
- Gross genomic damage measured by DNA image cytometry independently predicts gastric cancer patient survival (2009) (18)
- Urgent improvements needed to diagnose and manage Lynch syndrome (2017) (18)
- Extraction and amplification of DNA from archival haematoxylin and eosin sections and cervical cytology Papanicolaou smears. (1989) (17)
- No Significant Association Between the Fecal Microbiome and the Presence of Irritable Bowel Syndrome-type Symptoms in Patients with Quiescent Inflammatory Bowel Disease. (2018) (17)
- Association of Coloproctology of Great Britain & Ireland (ACPGBI): Guidelines for the Management of Cancer of the Colon, Rectum and Anus (2017) ‐ Pathology Standards and Datasets (2017) (17)
- Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesis (2021) (17)
- The sigmoid take-off: An anatomical imaging definition of the rectum validated on specimen analysis. (2020) (17)
- Congenital Torulopsis glabrata infection in man. (1980) (17)
- Experiences from the front-line routine consenting of surplus surgically removed tissue: without investment by the National Health Service fully informed consent for all is not available (2006) (17)
- PROGNOSIS IN MALIGNANT GLIOMA: A RETROSPECTIVE STUDY OF BIOPSY SPECIMENS BY FLOW CYTOMETRY (1989) (17)
- Deep Learning for the detection of microsatellite instability from histology images in colorectal cancer: a systematic literature review (2021) (16)
- Prenatal detection of trisomy 13 from amniotic fluid by quantitative fluorescent polymerase chain reaction (1998) (16)
- Examining the potential use and long-term stability of guaiac faecal occult blood test cards for microbial DNA 16S rRNA sequencing (2016) (16)
- Comparison of molecular and pathologic features of stage II and stage III colon cancer in four large studies conducted for development of the 12-gene colon cancer recurrence score. (2010) (16)
- New insights into the lymphovascular microanatomy of the colon and the risk of metastases in pT1 colorectal cancer obtained with quantitative methods and three‐dimensional digital reconstruction (2015) (16)
- DNA methylation, a biomarker for colorectal cancer: implications for screening and pathological utility. (2003) (16)
- Exploring the poor outcomes of BRAF mutant (BRAF mut) advanced colorectal cancer (aCRC): Analysis from 2,530 patients (pts) in randomized clinical trials (RCTs). (2015) (16)
- Preimplantation Genetic Diagnosis Using Fluorescent Polymerase Chain Reaction: Results and Future Developments (1999) (16)
- Detection of Common Viruses Using the Polymerase Chain Reaction to Assess Levels of Viral Presence in Type 1 (Insulin‐dependent) Diabetic Patients (1995) (16)
- Parathyroid hormone related peptide in ovarian carcinoma. (1990) (15)
- DNA aneuploidy and cell proliferation in familial adenomatous polyposis. (1988) (15)
- Working at the microscope: analysis of the activities involved in diagnostic pathology (2012) (15)
- Flow cytofluorometric analysis of serial biopsies of tumours of the uterine cervix. (1984) (15)
- Antenatal screening for cystic fibrosis (1996) (15)
- Flow cytometry and AgNORs in benign, borderline, and malignant mucinous and serous tumours of the ovary. (1993) (15)
- Is there a case for routine clinical application of ploidy measurements in gastrointestinal tumours? (2004) (14)
- Prognostic and predictive significance of proliferation in 867 colorectal cancers (2012) (14)
- Identification of 42 Genes Linked to Stage II Colorectal Cancer Metastatic Relapse (2016) (14)
- Association between family history and mismatch repair in colorectal cancer (2005) (14)
- Pathology is a necessary and informative tool in oncology clinical trials (2014) (14)
- Additional loss of MSH2 and MSH6 expression in sporadic deficient mismatch repair colorectal cancer due to MLH1 promoter hypermethylation (2019) (14)
- Evaluation of miR 31 3p as a biomarker of prognosis and panitumumab benefit in RAS-wt advanced colorectal cancer (aCRC): Analysis of patients (pts) from the PICCOLO trial. (2015) (13)
- Image-based consensus molecular subtype classification (imCMS) of colorectal cancer using deep learning (2019) (13)
- Morphometry of gastric carcinoma: Its association with patient survival, tumour stage, and DNA ploidy (1992) (13)
- Leveraging wall-sized high-resolution displays for comparative genomics analyses of copy number variation (2013) (13)
- Relationship between cell ploidy and glucocorticoid induced death in human lymphoid cell lines. (1984) (13)
- The correlation between endoscopic and histopathological measurements in colorectal polyps (2015) (13)
- Frequency of replication errors in colorectal cancer and their association with family history (1998) (13)
- Three-year survival result of CORE (Capecitabine, Oxaliplatin, Radiotherapy and Excision) study after post-operative chemotherapy in patients with locally advanced rectal adenocarcinoma (2009) (13)
- Regional multidisciplinary team intervention programme to improve colorectal cancer outcomes: study protocol for the Yorkshire Cancer Research Bowel Cancer Improvement Programme (YCR BCIP) (2019) (13)
- Cluster differentiation antigen expression, proliferative activity and clinical stage in centroblastic centrocytic lymphomas (1986) (13)
- Multimodal Imaging Techniques for the Extraction of Detailed Geometrical and Physiological Information for Use in Multi-Scale Models of Colorectal Cancer and Treatment of Individual Patients (2006) (12)
- A phase II single arm feasibility trial of neoadjuvant chemotherapy (NAC) with oxaliplatin/fluorouracil (OxMdG) then short-course preoperative radiotherapy (SCPRT) then immediate surgery in operable rectal cancer (ORC): COPERNICUS (NCT01263171). (2015) (12)
- An international phase II study of Capecitabine, Oxaliplatin, Radiotherapy and Excision (CORE) in patients with MRI-defined locally advanced rectal adenocarcinoma. Interim results. (2005) (12)
- Context Aware Colour Classification in Digital Microscopy (2011) (12)
- High gastric juice ascorbic acid concentrations in members of a gastric cancer family. (1993) (11)
- Comparison of FISH, PRINS, and Conventional and Fluorescent PCR for Single-Cell Sexing: Suitability for Preimplantation Genetic Diagnosis (1998) (11)
- The effect of a multidisciplinary regional educational programme on the quality of colon cancer resection (2018) (11)
- Acute renal failure complicating Legionnaires' disease. (1980) (11)
- Extraction of DNA from exfoliative cytology specimens and its suitability for analysis by the polymerase chain reaction (1990) (11)
- Detection of the Epidermal Growth Factor Receptor, Amphiregulin and Epiregulin in Formalin-Fixed Paraffin-Embedded Human Placenta Tissue by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging (2013) (11)
- Ploidy, proliferative activity, cluster differentiation antigen expression and clinical remission in highgrade non‐Hodgkin's lymphoma (1987) (11)
- Molecular markers of chemotherapeutic response and toxicity in colorectal cancer (2007) (11)
- A Retrospective Observational Study of the Relationship between Single Nucleotide Polymorphisms Associated with the Risk of Developing Colorectal Cancer and Survival (2015) (10)
- The anatomy of the perineal body in relation to abdominoperineal excision for low rectal cancer (2016) (10)
- ARISTOTLE: A phase III trial comparing concurrent capecitabine with capecitabine and irinotecan (Ir) chemoradiation as preoperative treatment for MRI-defined locally advanced rectal cancer (LARC). (2020) (10)
- Clinical and molecular characteristics and treatment outcomes of advanced right-colon, left-colon and rectal cancers: data from 1180 patients in a phase III trial of panitumumab with an extended biomarker panel. (2020) (10)
- DNA-ploidy studies in a keratocyst undergoing subsequent malignant transformation. (1987) (10)
- Role of the Oxidative DNA Damage Repair Gene OGG1 in Colorectal Tumorigenesis (2013) (10)
- 509PDPRIMARY TUMOUR LOCATION (PTL) AS A PROGNOSTIC AND PREDICTIVE FACTOR IN ADVANCED COLORECTAL CANCER (ACRC): DATA FROM 2075 PATIENTS (PTS) IN RANDOMISED TRIALS. (2014) (10)
- Quality of surgery: has the time come for colon cancer? (2015) (10)
- Flow cytometry in the quantitation of DNA aneuploidy and cell proliferation in human disease. (1990) (9)
- Preface to Genomic Pathology – a New Frontier (2001) (9)
- Detection of c-Ki-ras mutations in bile samples from patients with pancreatic and biliary cancers (1995) (9)
- Capecitabine Versus Active Monitoring in Stable or Responding Metastatic Colorectal Cancer After 16 Weeks of First-Line Therapy: Results of the Randomized FOCUS4-N Trial (2021) (9)
- Pathology--a molecular prognostic approach. (2002) (9)
- Molecular biology and infections of the gut. (1992) (9)
- Incorporating Local and Global Context for Better Automated Analysis of Colorectal Cancer on Digital Pathology Slides (2016) (9)
- Mutation Detection by Clonal Sequencing of PCR Amplicons and Grouped Read Typing is Applicable to Clinical Diagnostics (2013) (9)
- Confirmation that somatic mutations of beta‐2 microglobulin correlate with a lack of recurrence in a subset of stage II mismatch repair deficient colorectal cancers from the QUASAR trial (2019) (9)
- Quantitative assessment of tumor cell density in rectal cancer following three different preoperative therapies compared to surgery alone. (2010) (8)
- Rapid determination of trisomy 18 parental origin using fluorescent PCR and small tandem repeat markers: case reports (1998) (8)
- INFARCTION OF THE TONGUE IN WEGENER'S GRANULOMATOSIS (1992) (8)
- What can the molecular pathologist offer for optimal decision making? (2010) (8)
- Prognostic value of thymidylate synthase (TS) expression on failure-free survival of fluorouracil-treated metastatic colorectal cancer patients. (2006) (8)
- Microbiome Analysis of More Than 2,000 NHS Bowel Cancer Screening Programme Samples Shows the Potential to Improve Screening Accuracy (2021) (8)
- Comparing mutation calls in fixed tumour samples between the affymetrix OncoScan® array and PCR based next-generation sequencing (2017) (7)
- In-depth Clinical and Biological Exploration of DNA Damage Immune Response as a Biomarker for Oxaliplatin Use in Colorectal Cancer (2020) (7)
- Association of topoisomerase-1 (Topo1) with the efficacy of chemotherapy in a randomized trial for advanced colorectal cancer patients (FOCUS). (2006) (7)
- Prenatal detection of trisomy 21 by fluorescent polymerase chain reaction: importance of primer selection and criticism of an earlier report. (1997) (7)
- Two cases of primary malignant melanoma of the oesophagus. (1988) (7)
- Decoy receptor 1 (DCR1) promoter hypermethylation and response to irinotecan in metastatic colorectal cancer. (2017) (7)
- Ex vivo specimen MRI and pathology confirm a rectosigmoid mesenteric waist at the junction of the mesorectum and mesocolon (2020) (7)
- A Prototype Infrastructure for the Secure Aggregation of Imaging and Pathology Data for Colorectal Cancer Care (2006) (6)
- Screening sperm donors for cystic fibrosis (1995) (6)
- Combined epiregulin (EREG) and amphiregulin (AREG) expression levels as a biomarker of prognosis and panitumumab benefit in RAS-wt advanced colorectal cancer (aCRC). (2014) (6)
- Molecular approaches to colorectal cancer: a review (1998) (6)
- Addressing the variation in adjuvant chemotherapy treatment for colorectal cancer: Can a regional intervention promote national change? (2020) (6)
- Flat adenomas (1999) (6)
- Short Term Pathology Results from the First World Wide Randomised Trial of Robotic Versus Laparoscopic Resection for Rectal Cancer (ROLARR) (2016) (6)
- Towards automatic patient selection for chemotherapy in colorectal cancer trials (2014) (6)
- Further applications of the polymerase chain reaction (1989) (6)
- Decoy receptor 1 (DCR1) promoter hypermethylation and response to irinotecan in metastatic colorectal cancer (2017) (6)
- The polymerase chain reaction: The route to molecular histopathology (1989) (6)
- Radiologist and multidisciplinary team clinician opinions on the quality of MRI rectal cancer staging reports: how are we doing? (2019) (6)
- Molecular subtype-specific efficacy of anti-EGFR therapy in colorectal cancer is dependent on the chemotherapy backbone (2021) (6)
- The modern anatomical surgical approach to localised rectal cancer (2013) (6)
- Influence of age on surgical treatment and postoperative outcomes of patients with colorectal cancer in Denmark and Yorkshire, England (2021) (6)
- A New Image Registration algorithm with application to 3 D Histopathology (2008) (6)
- The Impact of Short Course Pre-operative Radiotherapy on Patients' Quality of Life: Data from the MRC CR07/NCIC CO16 Randomised Clinical Trial in Patients with Rectal Cancer (2008) (6)
- Next Generation intraoperative Lymph node staging for Stratified colon cancer surgery (GLiSten): a multicentre, multinational feasibility study of fluorescence in predicting lymph node-positive disease (2016) (5)
- Assessment of multiple markers for association with response rate (RR) and failure-free survival (FFS) in patients with advanced colorectal cancer (CRC) treated with chemotherapy in the MRC CR08 (FOCUS) randomized trial. (2004) (5)
- Staging of colorectal cancer (1987) (5)
- Preservation of gut microbiome following ridinilazole versus fidaxomicin treatment of Clostridium difficile infection (2017) (5)
- Artificial Intelligence–Assisted Amphiregulin and Epiregulin IHC Predicts Panitumumab Benefit in RAS Wild-Type Metastatic Colorectal Cancer (2021) (5)
- Ultrastructural study of Kaposi's sarcoma. (1996) (5)
- Lynch syndrome screening in colorectal cancer: results of a prospective 2‐year regional programme validating the NICE diagnostics guidance pathway throughout a 5.2‐million population (2021) (5)
- Preoperative Chemotherapy for Operable Colon Cancer: Mature Results of an International Randomized Controlled Trial (2023) (5)
- Kaposi's Sarcoma: A Clinico-Pathologic Overview (1991) (5)
- Association of molecular markers with toxicity outcomes in a randomized trial of chemotherapy for advanced colorectal cancer (FOCUS). (2006) (5)
- Protocol for a multicentre randomised feasibility trial evaluating early Surgery Alone In LOw Rectal cancer (SAILOR) (2016) (5)
- GEMS–RCPSG: ‘Is Academic Medicine for Me?’ National Conference 2011, 19 November 2011 (2012) (5)
- A new class of colorectal cancer gene. (1995) (5)
- The role of the longitudinal muscle in the anal sphincter complex (2020) (5)
- OC-074 Major improvement in the stage profile of tumours diagnosed in the NHS Bowel Cancer Screening Programme (2010) (4)
- The tissue microarray data exchange specification: Extending TMA DES to provide flexible scoring and incorporate virtual slides (2011) (4)
- The D prefix: toward a reproducible validated alternative end point in rectal cancer. (2015) (4)
- Colon cancer surgery: pathological quality control is essential for optimal outcomes (2018) (4)
- Experiences of running a stratified medicine adaptive platform trial: Challenges and lessons learned from 10 years of the FOCUS4 trial in metastatic colorectal cancer (2022) (4)
- Prospector: A web-based tool for rapid acquisition of gold standard data for pathology research and image analysis (2015) (4)
- Video. Fluorescent polymerase chain reaction: Part II. Detailed technique (1996) (4)
- Prognostic and Predictive Value of Tumor Budding in Colorectal Cancer. (2021) (4)
- Encrypted federated learning for secure decentralized collaboration in cancer image analysis (2022) (4)
- Polymerase chain reaction (PCR) on fixed necropsy material. (1990) (3)
- Carriage of adhesive Escherichia coli after restorative proctocolectomy and pouch anal anastomosis: relation with functional outcome and inflammation. (1993) (3)
- Abstract form for the Irish Journal of Medical Science v workshop on gastroduodenal pathology and Helicobacter pylori July 5th — 7th 1992 — Dublin, Ireland (1992) (3)
- Detection of somatic mutations in tumors using unaligned clonal sequencing data (2014) (3)
- FOCUS 3: A study to determine the feasibility of molecular selection of therapy using K-RAS, B-RAF, and topo-1 in patients with advanced colorectal cancer (ACRC). (2012) (3)
- OC-0219 THE MRC CR07 TRIAL NCIC CO16 TRIAL AFTER A MEDIAN FOLLOW UP OF 8 YEARS (2012) (3)
- Characterisation of dysplastic liver nodules using low‐pass DNA sequencing and detection of chromosome arm‐level abnormalities in blood‐derived cell‐free DNA (2021) (3)
- ACP Broadsheet 133: November 1992. Gross examination of the stomach. (1992) (3)
- Prognostic and predictive value of tumour budding in stage II colorectal carcinoma. (2015) (3)
- Molecular biology made easy. The polymerase chain reaction (1992) (3)
- The molecular revolution--coming your way soon. (1992) (3)
- The need for a revised staging system of metastatic (M) colorectal cancer (CRC): Evidence from a national perspective on survival following surgically treated (HPX) liver metastases. (2009) (3)
- Oral Poster Presentations (2012) (3)
- Reply to C. Zhuang et al. (2014) (2)
- Abstract 4446: Assessment of tissue composition with digital pathology in colorectal cancer (2019) (2)
- Expression of estrogen receptor β — comparison between invasive lobular and ductal cancers of the breast (2001) (2)
- Extending the tissue microarray data exchange specification for inclusion of data analysis results (2011) (2)
- Normal Large Intestine: Anatomy, Specimen Dissection and Histology Relevant to Pathological Practice (2012) (2)
- The role of the pathologist (2005) (2)
- Investigating the Faecal Microbiome in Formalin Fixed Paraffin Embedded (FFPE) Material (2015) (2)
- Colorectal Cancer: Pathology for the radiologist: pathological insights into colorectal cancer (2007) (2)
- Molecular markers to predict survival and benefit from adjuvant intraportal 5FU in colon cancer (1999) (2)
- What is the Role of the Neutrophil: Lymphocyte Ratio in Colorectal Cancer? (2021) (2)
- Hodgkin's disease: a flowcytometric study (1988) (2)
- 3D Histopathology of the Liver Using Dual Chromogen Histochemistry (2010) (2)
- OC-033 Nine-Gene Signature Implicated in the Early Development of Hepatitis C Virus (HCV) Related Hepatocellular Carcinoma (HCC) (2016) (2)
- Tumour deposits in colorectal cancer: the challenge is continuing (2008) (2)
- Quality of Surgery (2020) (2)
- FOCUS4: MAMS Trial Design in Action. Early Closure of FOCUS4-D (Pan-HER 1, 2 and 3 Inhibitor Versus Placebo) in Advanced Colorectal Cancer (aCRC) Patients, with Tumours Wildtype (WT) for KRAS, NRAS, BRAF and PIK3CA (2017) (2)
- FOxTROT: Randomized phase II study of neoadjuvant chemotherapy (CT) with or without an anti-EGFR monoclonal antibody for locally advanced, operable colon cancer: Planned interim report. (2011) (2)
- Luminal Bioavailability of Orally Administered ω-3 PUFAs in the Distal Small Intestine, and Associated Changes to the Ileal Microbiome, in Humans with a Temporary Ileostomy (2021) (2)
- Improving the management of early colorectal cancers (eCRC) by using quantitative markers to predict lymph node involvement and thus the need for major resection of pT1 cancers (2021) (2)
- What factors determine specimen quality in colon cancer surgery? A cohort study (2020) (2)
- Molecular markers and the prediction of prognosis and response to therapy in colon cancer (1999) (2)
- Developing a biomarker-stratified trial design in advanced colorectal cancer: The MRC FOCUS 3 feasibility study. (2011) (2)
- Blind total gastrectomy for massive bleeding from the stomach (1986) (2)
- Study to identify the optimum surgical technique in colon cancer (2014) (2)
- Oral nelfinavir before and during radiation therapy for rectal cancer: Changes in tumor perfusion and correlation between tissue and radiological markers of response. (2014) (2)
- 545P Epidermal growth factor receptor (EGFR) copy number (CN) as a biomarker of prognosis and panitumumab (Pan) benefit in RAS-wt advanced colorectal cancer (aCRC) (2017) (2)
- Genomics in Colorectal Cancer: Godsend or Gimmick? (2003) (1)
- Artificial intelligence-assisted immunohistochemical (IHC) evaluation of tumor amphiregulin (AREG) and epiregulin (EREG) expression as a combined predictive biomarker for panitumumab (Pan) therapy benefit in RAS wild-type (wt) metastatic colorectal cancer (mCRC): Analysis within the phase III PICCOL (2021) (1)
- Trials Symposium (2014) (1)
- Quality-of-life outcomes in older patients with early-stage rectal cancer receiving organ-preserving treatment with hypofractionated short-course radiotherapy followed by transanal endoscopic microsurgery (TREC): non-randomised registry of patients unsuitable for total mesorectal excision (2022) (1)
- Deletion of Chromosome 4q Predicts Outcome in Stage II Colon Cancer Patients (2010) (1)
- EnROL: A multicentre randomised trial of conventional versus laparoscopic surgery for colorectal cancer within an enhanced recovery programme (2012) (1)
- Pre-operative FOLFOX chemotherapy in advanced colon cancer: Pathology analysis of the FOxTROT trial (2019) (1)
- Bevacizumab and combination chemotherapy in rectal cancer until surgery (BACCHUS): A phase II, multicenter, open-label, randomized study of neoadjuvant chemotherapy alone without radiation in patients with MRI-defined high-risk cancer of the rectum not threatening the circumferential margin. (2014) (1)
- KRAS and BRAF Mutational Status can be Accurately Determined on Diagnostic Tissue Biopsies: An Analysis of Matched Biopsy and Resection Material from Patients with Colon Cancer in the NCRI FOxTROT trial (2012) (1)
- RNA gene expression signatures and DNA copy number changes in hepatocellular carcinoma formalin-fixed paraffin-embedded archived samples compared to fresh and normal tissues from the same patients (2006) (1)
- Residual Tumour Cell Density and the Relationship to Survival Following Pre-Operative Chemoradiation in Locally Advanced Rectal Cancer: Results of the NWCOG RICE Trial (2015) (1)
- OP26. Assessing the relative costs of standard open surgery and laparoscopic surgery in colorectal cancer in a randomised controlled trial (1997) (1)
- Fully transformer-based biomarker prediction from colorectal cancer histology: a large-scale multicentric study (2023) (1)
- 62. The virtual surgical pelvis: A highly-detailed 3D pelvic model for anatomical education and surgical simulation (2014) (1)
- Gaining biomarker insights from existing stage II colorectal cancer (CRC) patient cohorts in the United Kingdom: Using real-world data to guide treatment decisions. (2017) (1)
- HER3 as a biomarker of prognosis and panitumumab (Pan) benefit in RAS-wt advanced colorectal cancer (aCRC) (2015) (1)
- Pretreatment and postresection epidermal growth factor receptor (EGFR) pathway mutations in a prospective phase II trial (EXCITE) of preoperative cetuximab-containing chemoradiation (CRT) in locally advanced rectal cancer (LARC). (2014) (1)
- Generalizable biomarker prediction from cancer pathology slides with self-supervised deep learning: A retrospective multi-centric study (2023) (1)
- Biomodulation of irinotecan using ciclosporin: Results of PICCOLO, a randomized controlled trial in advanced colorectal cancer (aCRC). (2011) (1)
- Differences in the management of patients requiring an emergency resection for colonic cancer in two European populations (2022) (1)
- 2087 The development of a 3D anatomical atlas of the pelvis: Taking the next step in enhancing surgical anatomical education and clinical guidance (2015) (1)
- Will Extralevator Abdominoperineal Excision Become the New Gold Standard (2012) (1)
- Topoisomerase-1 (Topo1) as a predictive and prognostic factor in colorectal cancer chemotherapy (2009) (1)
- Reduce Academic Fatigue and Enhance Retention for The Determined Ones (TDOs) in Online Learning (2021) (1)
- 90th Annual Convention Poster Presentations and Abstracts (1991) (1)
- BACCHUS: A randomised study of neoadjuvant chemotherapy alone in patients with high-risk locally advanced rectal cancer. (2017) (1)
- Exploring the utility and acceptability of Faecal immunochemical testing (FIT) as a novel intervention for the improvement of colorectal Cancer (CRC) surveillance in individuals with lynch syndrome (FIT for lynch study): a single-arm, prospective, multi-centre, non-randomised study (2022) (1)
- P3.03-005 Inhibition of PRMT5 is Synthetic Lethal in Mesotheliomas Harboring MTAP Loss: Topic: Mesothelioma Transitional (2017) (1)
- Oral maintenance capecitabine versus active monitoring for patients with metastatic colorectal cancer (mCRC) who are stable or responding after 16 weeks of first-line treatment: Results from the randomized FOCUS4-N trial. (2021) (1)
- Exploiting Warburg's Effect for Clinical Gain: Pdk-3 is a Potential Target for Mitochondrial Modulation in Colorectal Cancer (CRC) (2010) (1)
- Improving Quality of Colon Cancer Surgery Through Surgical Education (2010) (1)
- Supporting Teacher Development on the Web (2008) (1)
- Abstract LB129: Stratification of radiotherapy and fluoropyrimidine-based chemotherapy from multi-omic profiling in rectal cancer biopsies (2021) (1)
- Creating Your Own Professional Development and Lifelong Learning Plan (2020) (1)
- 144 Quality control of rectal surgery, a must? (2009) (1)
- Fostering the Role of Pathology in Research (2009) (1)
- Role of derived neutrophil lymphocyte ratio as a biomarker in advanced colorectal cancer (2014) (1)
- Helicobacter pylori Detection by Polymerase Chain Reaction of the Gene Encoding 16S Ribosomal RNA in Fresh and Paraffin-Embedded Material (1993) (1)
- Improving the management of early colorectal cancer: assessment of quantitative markers to predict the need for major resection (2017) (1)
- FOxTROT:Randomized phased II study of neoadjuvant chemotherapy with or without an anti-EGFR monoclonal antibody for locally advanced, operable colon cancer. (2010) (1)
- The Six Best Abstracts (2018) (1)
- Gastrointestinal tumors, colorectal (2012) (1)
- p53 allelic imbalance in astrocytoma detected using fluorescent PCR of microsatellite repeat polymorphisms (1995) (1)
- Adventitial fibromuscular dysplasia and ischaemic bowel (1984) (1)
- Sustainable Leadership in a Post Pandemic HE World (2021) (0)
- Reflective Writing and Its Potential for Developing Teacher Leaders (2020) (0)
- Teacher Knowledge Development (2020) (0)
- Online Student Teaching Practicums During COVID-19: A Successful Case in the UAE (2023) (0)
- Invited commentary (2005) (0)
- Action research in the Middle East and North Africa (MENA) (2023) (0)
- Professional Development Learning Plans (2021) (0)
- [Close teamwork between pathologist and surgeon can improve results in colorectal cancer treatment]. (2011) (0)
- Developing Teachers as Leaders (2021) (0)
- 431P The FOCUS4-N trial results and individual patient data meta-analysis (IPDM) of maintenance therapy versus active monitoring for patients with metastatic colorectal cancer (mCRC) (2021) (0)
- List of Figures and Tables (2006) (0)
- Supporting English language teachers doing further degrees at a distance:a web based strategy researched (2006) (0)
- How the Most Productive TESOLers Fit it all in: Strategies for Productivity and Efficiency (2020) (0)
- ELT Management and Leadership Training (2020) (0)
- Dr. Quirke replies (1987) (0)
- A Career Impacted (2020) (0)
- An Approach to Using Reflective Writing to Develop Teacher Leaders (2020) (0)
- Relationship Between Baseline Rectal Tumor Length and Magnetic Resonance Tumor Regression Grade Response to Chemoradiotherapy: A Subanalysis of the TRIGGER Feasibility Study (2022) (0)
- Reflective Writing to Develop Teacher Leaders (2020) (0)
- The Leeds Powerwall Project (LEEP) (2013) (0)
- FOCUS4 biomarker laboratories: from the benefits to the practical and logistical issues faced during 6 years of centralised testing (2022) (0)
- Analysis of membrane metallopeptidases NEPand ECE expression in prostate cancer tissue microarrays (2005) (0)
- There are Significant Differences in Copy Number Variation Between Microsatellite-Stable and Instable Cases in Stage II/III Colorectal Cancer (2013) (0)
- Mycobacterium paratuberculosis DNA not detected in Crohn ' s disease tissue byfluorescent polymerase chain reaction Characteristics of patients Crohn ' s Ulcerative disease colitis Controls (2006) (0)
- PWE-147 Human Herpesvirus and Adenovirus Unique Genetic Sequences Detected in Hepatocellular Cancer Genomes (2013) (0)
- P QUIRKE carcinoma The role of microsatellite instability in gastric (1998) (0)
- Subject Index Vol. 30, Suppl. 2, 2012 (2012) (0)
- Abstract 626: Cross-site reproducibility and orthogonal validation of copy number and somatic mutation calls of OncoScan® FFPE Assay Kit in solid tumors (2015) (0)
- 6012 POSTER DISCUSSION Improved Oncological Outcome After Modified Extralevator Abdominoperineal Excision in Low Rectal Cancer Patients (2011) (0)
- Mismatch Repair Testing in Colorectal Cancer - Is Less More? (2012) (0)
- Abstracts of the Association of Coloproctology of Great Britain and Ireland Annual Meeting. June 8-11, 2009. Harrogate, United Kingdom. (2009) (0)
- Molecular Biology Of Digestive Disease (1994) (0)
- Pathology of the mesorectum — Implications for routine reporting (1997) (0)
- Cross-laboratory validation of the OncoScan® FFPE Assay, a multiplex tool for whole genome tumour profiling (2015) (0)
- Nucleic Acids Research (0)
- Chapter 5 Promoter CpG island hypermethylation patterns in polypoid and nonpolypoid colorectal adenomas (2013) (0)
- Colorectal Cancer: Updated Royal College of Pathologists’ Guidelines (2015) (0)
- Immunohistochemical assessment of p53 and Bcl2 does not predict response to 5-FU for colon cancer patients in the AXIS trial (2000) (0)
- Patient self-reported bladder function: further information (2019) (0)
- TECHNIQUES Tissue extraction of DNA and RNA and analysis by the polymerase chain reaction (0)
- Somatic Mutations of Beta2-Microglobulin are Correlated with a Lack of Disease Recurrence in a Subset of Stage II Mismatch Repair Deficient Colorectal Cancers from the QUASAR Trial (2018) (0)
- A Machine Learning Model of Complete Response to Radiation in Rectal Cancer Reveals Immune Infiltrate and TGFβ Signalling as Key Predictors (2022) (0)
- Association between artificial intelligence (AI) -assisted tumor AREG and EREG immunohistochemistry (IHC) and outcomes from anti-EGFR therapy during the routine management of metastatic colorectal cancer (mCRC): An observational cohort study. (2023) (0)
- Storage and analysis of microarray data (2005) (0)
- Assessment of rat colonic tumours by flow cytometry: Metastases are commonly DNA aneuploid (1987) (0)
- End-of-trial documentation (2016) (0)
- INTER-LABORATORY PRE-VALIDATION OF THE FOCUS4 PERSONALISED THERAPY TRIAL (2014) (0)
- The Three-Dimensional Anatomy of the Anal Sphincter Complex and its Relevance to Low Rectal and Anal Pathology (2015) (0)
- Abstracts of the Association of Coloproctology of Great Britain and Ireland Annual Meeting. July 1-3, 2012. Dublin, Ireland. (2012) (0)
- Pathology and Staging (2001) (0)
- 09.00 -12.00 Standard of Care and Outlook to the Future in … … Colon Cancer (2013) (0)
- Comparison of Mutational Status in the EGFR Pathway Across Four Different Platforms in the Fluoropyrimidine Oxaliplatin and Targeted Receptor Pre-Operative Therapy (FOxTROT) Trial (2018) (0)
- Authors' reply (1996) (0)
- Are Current Automated Approaches for Determining the Phylogeny of Multiple Deposits Capable of Interpreting the Complexity of Cancer Evolution (2015) (0)
- The Site of the Tumor, Not the Type of Operation, Determines the Worse Prognosis of the Low Rectal Cancer (2006) (0)
- Loss of pTEN Expression is Strongly Associated with the Presence of the BRAF V600E Mutation, and Further Complicates Combination Treatment Strategies for Patients with Advanced Colorectal Cancer (2015) (0)
- Diagnosis ofcomplete molar pregnancy by microsatellites inarchival material (1993) (0)
- Silver jubilee of the Royal College of Pathologists (1987) (0)
- Defining the Rectum and Sigmoid Colon: Should We Abolish the Term 'Rectosigmoid' to Improve Outcomes in Colorectal Cancer? (2015) (0)
- 5-aminolevulinic acid prescription and guidance for reconstitution (2016) (0)
- Secrets from the microbiome: molecular biology meets microbiology meets histopathology … meets clinical biochemistry (2015) (0)
- Investigating the poor outcomes of BRAF -mutant advanced colorectal cancer to develop practical treatment strategies (2017) (0)
- Colorectal cancer (1994) (0)
- HER1-3 inhibition in patients with colorectal cancer that is wild-type for BRAF, PIK3CA, KRAS, and NRAS mutations (FOCUS-4D): first results from the multi-arm multi-stage phase II/III FOCUS-4 randomised trial (2017) (0)
- Analysis of an Indian colorectal cancer faecal microbiome collection demonstrates universal colorectal cancer-associated patterns, but closest correlation with other Indian cohorts (2022) (0)
- 1050 poster CHANGES IN TUMOUR PERFUSION INDUCED BY NELFINAVIR AND RADIOTHERAPY: TRANSLATION TO A PHASE I-II CLINICAL TRIAL (2011) (0)
- Pathology in surgical practice. G. J. Hadfield, M. Hobsley and B. C. Morson (Eds). Edward Arnold, Maidenhead, 1985. No. of pages: ix + 500. Price: £49.50. ISBN: 0 7131 4471 8 (1987) (0)
- Lymphatic vessel distribution in the mucosa and submucosa and potential implications for T1 colorectal tumours (2010) (0)
- Trial case report forms (2016) (0)
- Comparison of Mutational Calls Obtained with Pyrosequencing and the Affymetrix OncoScan (R) FFPE Assay in Patients with Colon Cancer Recruited to the NCRI FOxTROT Trial (2015) (0)
- Comparing Gene Copy Number Status of Receptor Tyrosine Kinase and Downstream Signalling Genes Between Oesophageal and Gastric Cancer (2017) (0)
- Trials Symposium (2013) (0)
- Potential of Molecular Biology in Preoperative Evaluation (1997) (0)
- Posters (2010) (0)
- COLORECTAL CANCER. AUTHORS' REPLY (1994) (0)
- DEFICIENT MISMATCH REPAIR (DMMR) AND BRAF MUTATION (MT) STATUS IN PATIENTS (PTS) WITH METASTATIC COLORECTAL CANCER (MCRC): A META-ANALYSIS OF THE CAIRO, CAIRO2, COIN AND FOCUS STUDIES (2012) (0)
- 93rd annual convention podium and poster abstracts (1994) (0)
- DNA ploidy is an independent prognostic factor but not a predictive factor in sporadic colorectal cancer (2002) (0)
- The isolation and characterisation of circulating tumour cells from patients with hepatocellular carcinoma (2016) (0)
- Artificial intelligence-assisted evaluation of tumor infiltrating CD3+ and CD8+ T cells for prognostication and prediction of benefit from adjuvant chemotherapy in early stage colorectal cancer (CRC): A retrospective analysis of the QUASAR trial. (2023) (0)
- carcinomarole of microsatellite instability in gastric (2006) (0)
- Supporting undergraduate teaching in histopathology with virtual microscopy (2006) (0)
- The risk of colorectal cancer in individuals with mutations of the cystic fibrosis transmembrane conductance regulator (CFTR) gene: An English population-based study. (2022) (0)
- Will the Extra Levator Approach for Low Rectal Cancer Become the New Gold Standard (2018) (0)
- MCMs and geminin: Similar expression but different relationship to survival in small bowel compared to gastric cancer (2006) (0)
- A prospective phase II study of pre-operative chemotherapy then short-course radiotherapy for high risk rectal cancer: COPERNICUS (2018) (0)
- Adenoma screening and colorectal cancer. (1991) (0)
- The potential of the microbiome for colorectal cancer screening (2016) (0)
- Bevacizumab and Combination Chemotherapy in rectal cancer Until Surgery (BACCHUS): a phase II, multicentre, open-label, randomised study of neoadjuvant chemotherapy alone in patients with high-risk cancer of the rectum (2015) (0)
- laparoscopic colorectal surgery so that their patients might benefit from its advantages. (2014) (0)
- An Evaluation of Culture Techniques versus 16S Profiling for Investigation of Antibiotic-Mediated Alteration of Microbiota Populations within a Clinically Reflective In Vitro Model of the Human Gut (2015) (0)
- Distribution and Quantification of Vessels in Normal Colorectal Tissue (2010) (0)
- Reply (1994) (0)
- Tumor deposits in colorectal cancer: Refining their definition in the TNM system (2023) (0)
- Prognostic Factors and Colorectal Cancer; Markers in Context (2017) (0)
- PWE-044 Inter-Tumour Heterogeneity in Hepatitis C Virus (HCV) Related Multi-Focal Hepatocellular Carcinoma (HCC) (2016) (0)
- Edinburgh Research Explorer Image-based consensus molecular subtype (imCMS) classification of colorectal cancer using deep learning (2020) (0)
- ACP Broadsheet 133 Gross examination of the stomach (2004) (0)
- 196. Rectal pathology (2012) (0)
- Prognostic value of p53, hMLH1, hMSH2, MGMT and COX-2 in the QUASAR-1 Dukes' stage B colorectal cancer cohort (2002) (0)
- Molecular selection of therapy in metastatic colorectal cancer: the FOCUS4 molecularly stratified RCT (2022) (0)
- Short report Direct multiplex amplification of DNA from a formalin fixed, paraYn wax embedded tissue section (2000) (0)
- THE EFFECT OF SINGLE NUCLEOTIDE POLYMORPHISMS ON CLINICAL OUTCOME AND SURVIVAL IN THE FOCUS (FLUOROURACIL, OXALIPLATIN AND IRINOTECAN: USE AND SEQUENCING) CLINICAL TRIAL OF METASTATIC COLORECTAL CANCER (2016) (0)
- Identifying molecular markers predictive of survival and benefit from adjuvant 5-fluorouracil in colon cancer (1998) (0)
- Sa1943 Histopathologic Grading Using Poorly-Differentiated Clusters Predicts Outcome in Colorectal Carcinoma (2014) (0)
- Current status of measurement of DNA content. (1987) (0)
- Characterising the Gastrointestinal Microbiome in Comorbid Inflammatory Bowel Disease and Irritable Bowel Syndrome (2017) (0)
- Reply to: Does MRI Restaging of Rectal Cancer After Chemoradiotherapy Actually Permit a Change in Surgical Management? (2017) (0)
- DCR1 promoter hypermethylation and response to irinotecan in metastatic colorectal cancer (2016) (0)
- Clinical expert letter:: Improving the identification and management of Lynch syndrome in the UK (2017) (0)
- Correspondence Dna Aneuploidy in Ulcerative Colitis (0)
- Abstracts of the ESCP 9th Scientific and Annual Meeting, 24-26 September 2014, Barcelona, Spain. (2014) (0)
- Authors' reply (1990) (0)
- Whole genome sequencing of 2,023 colorectal cancers reveals mutational landscapes, new driver genes and immune interactions (2022) (0)
- Reply to D.J. Sargent et al. (2016) (0)
- What can the Pathologist Tell the Multidisciplinary Team about Rectal Cancer Resection (2008) (0)
- Comparison of Histologically Normal Mucosa and Blood as Controls for Targeted Next Generation Sequencing Analysis in Patients with Colon Cancer in the NCRI FOxTROT Trial (2015) (0)
- PIK3CA Mutation is Strongly Associated with K-ras 12/13 Mutation in Stage II/III Colorectal Cancer (2012) (0)
- PWE-045 A Strong Correlation Exists between Morphologic and Genomic Heterogeneity in Hepatocellular Carcinoma (HCC) (2016) (0)
- Histopathological Downstaging of Colon Cancer Following Six Weeks of Pre-operative Chemotherapy: Early Results of the NCRI FOxTROT Trial (2012) (0)
- Abstracts of the Association of Coloproctology of Great Britain and Ireland Annual Meeting. July 1-3, 2013. Liverpool, United Kingdom. (2013) (0)
- Reporting colorectal cancer (2007) (0)
- Genetic predisposition and abnormalities in gastric cancer (1994) (0)
- Erratum : Deletion of chromosome 4q predicts outcome in Stage II colon cancer patients (Analytical Cellular Pathology (2010) 33: 2 (95-104)) (2011) (0)
- Exploring the suitability and stability of guaiac faecal occult blood test cards to isolate microbial DNA for 16srRNA sequencing (2016) (0)
- 189PFCγRIIa and FCγRIIIa single nucleotide polymorphisms (SNPs) and cetuximab benefit in the EXCITE trial (2017) (0)
- Comparing mutation calls in fixed tumour samples between the affymetrix OncoScan® array and PCR based next-generation sequencing (2017) (0)
- The Grb2 splice variant, Grb3-3, is a negative regulator of RAS activation (2022) (0)
- Lunchtime Poster Presentations (2009) (0)
- Immune status is prognostic for poor survival in colorectal cancer patients and is associated with tumour hypoxia (2020) (0)
- MRC CLASICC trial – Authors' reply (2005) (0)
- Gastrointestinal Pathology (2012) (0)
- Parathryroid hormone related peptide in normal human development (1990) (0)
- 16.29: Reproducibility of Left Ventricular Ejection Fraction Assessments by 64-Slice Multidetector Row Computed Tomography (2007) (0)
- Whole-Mount Microscopic Sections Reveal that Denonvilliers' Fascia is One Entity and Adherent to the Mesorectal Fascia: Should we still Question the Anterior Plane in TME? (2015) (0)
- THE NM23 GENE AND COLORECTAL CANCER. AUTHOR'S REPLY (1994) (0)
- 1041 NEXT GENERATION SEQUENCING USED TO MAP EARLY GENETIC LESIONS IN HEPATOCELLULAR CANCER PROGRESSION (2013) (0)
- Genetic predisposition and abnormalities in gastric cancer : Gastric carcinogenesis (1994) (0)
- MRC CLASICC trial - reply (2005) (0)
- Title: Image-based consensus molecular subtype classification (imCMS) of colorectal cancer using deep learning (2019) (0)
- Exploring outcomes of RAS-mutant (RAS mut) advanced colorectal cancer (aCRC) treated with chemotherapy: Analysis from 2254 patients (pts) in randomised clinical trials (RCTs). (2016) (0)
- Comparison of Mismatch Repair Protein Expression Between Biopsies and Resections in Advanced Colon Cancer from the Phase II Group of the Fluoropyrimidine Oxaliplatin and Targeted Receptor Pre-Operative Therapy (FOxTROT) Trial (2018) (0)
- Abstracts of Cardiff Pathology 2009, the Fifth Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain and Ireland. June 30-July 3, 2009. Cardiff, United Kingdom. (2009) (0)
- The colorectal cancer-associated faecal microbiome of developing countries resembles that of developed countries (2021) (0)
- Divergent oncogenic changes influence survival differences between colon and rectal adenocarcinomas (2009) (0)
- The evolutionary landscape of colorectal tumorigenesis (2018) (0)
- CONSIDERATIONS IN THE DEVELOPMENT AND VALIDATION OF GENOMIC TESTS FOR CANCER RECURRENCE AND TREATMENT BENEFIT (2010) (0)
- 6.0: Assessment of the range of normal left ventricular volumes in a patient population with normal ejection fraction and correlation with other modalities of ejection fraction estimation (2007) (0)
- The Authors Reply. (2016) (0)
- MCM proteins and geminin in gastric cancer: Association with prognosis, histological type, DNA ploidy and proliferation (2005) (0)
- The clinical relevance of tumor RAS/TP53 dual mutation in early and metastatic colorectal cancer (CRC). (2022) (0)
- University of Birmingham Investigating the poor outcomes of BRAF-mutant advanced colorectal cancer (2017) (0)
- Patient stratification into robust cancer-cell intrinsic subtypes from colorectal cancer biopsies may inform prospective clinical trials (2018) (0)
- 553PTHE DERIVED NEUTROPHIL LYMPHOCYTE RATIO (DNLR) AS A BIOMARKER IN ADVANCED COLORECTAL CANCER (ACRC). (2014) (0)
- Implementation of a digital ecosystem to develop clinical algorithms (2019) (0)
- Pre-Treatment and Post-Treatment Epidermal Growth Factor Receptor Pathway Mutations in a Prospective Phase II Trial (NWCOG EXCITE) of Cetuximab-Containing Chemoradiation in Locally Advanced Rectal Cancer (2015) (0)
- Introduction to Flow Cytometry (1992) (0)
- The Effect of Multidisciplinary Education on the Quality of Colon Cancer Resection (2015) (0)
- An e-learning system using virtual slides (2005) (0)
- Characterising the Oral and Bowel Microbiome as a Prelude to Understanding its Role in Cancer Development Using a Next Generation Sequencing Approach (2015) (0)
- Commentary on Demetter et al. (2013) (0)
- Clinical Practice and Management Strategy at a Coloproctology Center in South Korea (2018) (0)
- A searchable online database of virtual slides. (2005) (0)
- Objectives: To assess the variation in risk-adjusted 30-day post-operative mortality for colorectal cancer patients between Hospital Trusts within the English NHS. Design: Retrospective cross sectional population-based study of data extracted from the National Cancer Data Repository Setting: All pro (2016) (0)
- Literature review search strategies (2016) (0)
- Assay result variability during determination of mismatch repair deficiency status using immunohistochemistry: A transatlantic comparative study. (2011) (0)
- Investigating the Challenges of Using Historical Formalin-Fixed Paraffin-Embedded (FFPE) Material from the MRC CR07 Rectal Cancer Trial Using the Affymetrix OncoScan (R) FFPE Assay and Next Generation Sequencing (2015) (0)
- 337P Prediction of poor response to oxaliplatin by an RNA signature derived and validated in colorectal cancer clinical trials (2022) (0)
- DNA aneuploidy in ulcerative colitis. (1987) (0)
- Pre-operative tumour marker status predicts recurrence and survival after complete cytoreduction and hyperthermic intraperitoneal chemotherapy for Pseudomyxoma Peritonei : outcome in 519 patients (2013) (0)
- The MERCURY II Study: Prospective Validation of a Low Rectal Cancer Assessment System Using Magnetic Resonance Imaging, and Development of a Local Recurrence Risk Stratification Model (2016) (0)
- Small bowel adenocarcinomas are more similar to colorectal than gastric cancer according to their chromosomal copy number profile (2010) (0)
- The use of Affymetrix OncoScan to Validate Biomarker Screening Results in Patients Enrolled in the MRC FOCUS4 Trial: The Quest to Get More, from Less (2017) (0)
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