Philipp E. Scherer
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Swiss American professor of medicine
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Philipp E. Schererbiology Degrees
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Philipp E. Scherer's Degrees
- Doctorate Medicine University of Geneva
- PhD Biochemistry University of Geneva
Why Is Philipp E. Scherer Influential?
(Suggest an Edit or Addition)Philipp E. Scherer's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A Novel Serum Protein Similar to C1q, Produced Exclusively in Adipocytes (*) (1995) (3175)
- The adipocyte-secreted protein Acrp30 enhances hepatic insulin action (2001) (2562)
- Adipose tissue, inflammation, and cardiovascular disease. (2005) (1711)
- Caveolins, a Family of Scaffolding Proteins for Organizing “Preassembled Signaling Complexes” at the Plasma Membrane* (1998) (1535)
- Adipose tissue remodeling and obesity. (2011) (1489)
- Obesity-associated improvements in metabolic profile through expansion of adipose tissue. (2007) (1242)
- Visceral Fat Adipokine Secretion Is Associated With Systemic Inflammation in Obese Humans (2007) (1221)
- Minireview: The adipocyte--at the crossroads of energy homeostasis, inflammation, and atherosclerosis. (2003) (1220)
- ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism (2002) (1195)
- Complex Distribution, Not Absolute Amount of Adiponectin, Correlates with Thiazolidinedione-mediated Improvement in Insulin Sensitivity* (2004) (1178)
- Caveolins, Liquid-Ordered Domains, and Signal Transduction (1999) (1055)
- Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis (2012) (980)
- Tracking adipogenesis during white adipose tissue development, expansion and regeneration (2013) (974)
- Characterization of caveolin-rich membrane domains isolated from an endothelial-rich source: implications for human disease (1994) (933)
- Structure-Function Studies of the Adipocyte-secreted Hormone Acrp30/Adiponectin (2003) (929)
- Endogenous glucose production is inhibited by the adipose-derived protein Acrp30. (2001) (910)
- Metabolic Dysregulation and Adipose Tissue Fibrosis: Role of Collagen VI (2008) (850)
- Expression cloning of SR-BI, a CD36-related class B scavenger receptor. (1994) (840)
- Adiponectin acts in the brain to decrease body weight (2004) (801)
- Adiponectin – journey from an adipocyte secretory protein to biomarker of the metabolic syndrome (2005) (793)
- Molecular Cloning of Caveolin-3, a Novel Member of the Caveolin Gene Family Expressed Predominantly in Muscle (*) (1996) (761)
- Adipose Tissue (2006) (758)
- Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin (2011) (738)
- Regulation of Fasted Blood Glucose by Resistin (2004) (725)
- Expression of Caveolin-3 in Skeletal, Cardiac, and Smooth Muscle Cells (1996) (700)
- The crystal structure of a complement-1q family protein suggests an evolutionary link to tumor necrosis factor (1998) (671)
- Hypoxia-Inducible Factor 1α Induces Fibrosis and Insulin Resistance in White Adipose Tissue (2009) (669)
- Adiponectin, Leptin, and Fatty Acids in the Maintenance of Metabolic Homeostasis through Adipose Tissue Crosstalk. (2016) (668)
- Fibrosis and adipose tissue dysfunction. (2013) (664)
- Caveolae, caveolin and caveolin-rich membrane domains: a signalling hypothesis. (1994) (653)
- Adipogenesis and metabolic health (2019) (649)
- Mice Lacking Adiponectin Show Decreased Hepatic Insulin Sensitivity and Reduced Responsiveness to Peroxisome Proliferator-activated Receptor γ Agonists* (2006) (636)
- Adipose tissue-derived factors: impact on health and disease. (2006) (627)
- Identification, sequence, and expression of caveolin-2 defines a caveolin gene family. (1996) (588)
- Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice. (2011) (585)
- Removal of visceral fat prevents insulin resistance and glucose intolerance of aging: an adipokine-mediated process? (2002) (577)
- Caveolin-1-deficient Mice Are Lean, Resistant to Diet-induced Obesity, and Show Hypertriglyceridemia with Adipocyte Abnormalities* (2002) (572)
- Flotillin and Epidermal Surface Antigen Define a New Family of Caveolae-associated Integral Membrane Proteins* (1997) (560)
- Sexual differentiation, pregnancy, calorie restriction, and aging affect the adipocyte-specific secretory protein adiponectin. (2003) (559)
- Oligomeric structure of caveolin: implications for caveolae membrane organization. (1995) (558)
- Adiponectin: mechanistic insights and clinical implications (2012) (549)
- Induction of Adipocyte Complement-Related Protein of 30 Kilodaltons by PPARγ Agonists: A Potential Mechanism of Insulin Sensitization. (2002) (546)
- Adipose-derived resistin and gut-derived resistin-like molecule-beta selectively impair insulin action on glucose production. (2003) (536)
- Lipid homeostasis, lipotoxicity and the metabolic syndrome. (2010) (535)
- Obesity and cancer—mechanisms underlying tumour progression and recurrence (2014) (528)
- A transgenic mouse with a deletion in the collagenous domain of adiponectin displays elevated circulating adiponectin and improved insulin sensitivity. (2004) (528)
- Adipokines as novel biomarkers and regulators of the metabolic syndrome (2010) (522)
- The Hyperglycemia-induced Inflammatory Response in Adipocytes (2005) (516)
- Adipocyte inflammation is essential for healthy adipose tissue expansion and remodeling. (2014) (504)
- Targeting adipose tissue in the treatment of obesity-associated diabetes (2016) (483)
- Cell-type and Tissue-specific Expression of Caveolin-2 (1997) (477)
- The cell biology of fat expansion (2015) (438)
- An FGF21-adiponectin-ceramide axis controls energy expenditure and insulin action in mice. (2013) (437)
- A haplotype at the adiponectin locus is associated with obesity and other features of the insulin resistance syndrome. (2002) (435)
- From Lipid Storage Compartment to Endocrine Organ (2006) (420)
- Induction of caveolin during adipogenesis and association of GLUT4 with caveolin-rich vesicles (1994) (408)
- The ominous triad of adipose tissue dysfunction: inflammation, fibrosis, and impaired angiogenesis. (2017) (402)
- Adipocyte-derived collagen VI affects early mammary tumor progression in vivo, demonstrating a critical interaction in the tumor/stroma microenvironment. (2005) (386)
- Specific Inhibitors of p38 Mitogen-activated Protein Kinase Block 3T3-L1 Adipogenesis* (1998) (378)
- Gluttony, sloth and the metabolic syndrome: a roadmap to lipotoxicity (2010) (376)
- Jnk1 but not jnk2 promotes the development of steatohepatitis in mice (2006) (375)
- Caveolin Isoforms Differ in Their N-terminal Protein Sequence and Subcellular Distribution. IDENTIFICATION AND EPITOPE MAPPING OF AN ISOFORM-SPECIFIC MONOCLONAL ANTIBODY PROBE (*) (1995) (373)
- The Lipopolysaccharide-activated Toll-like Receptor (TLR)-4 Induces Synthesis of the Closely Related Receptor TLR-2 in Adipocytes* (2000) (361)
- Direct insulin and leptin action on pro-opiomelanocortin neurons is required for normal glucose homeostasis and fertility. (2010) (359)
- Role of resistin in diet-induced hepatic insulin resistance. (2004) (357)
- Caveolin-1-deficient mice show insulin resistance and defective insulin receptor protein expression in adipose tissue. (2003) (355)
- Adiponectin, the past two decades. (2016) (354)
- Adipocyte-secreted factors synergistically promote mammary tumorigenesis through induction of anti-apoptotic transcriptional programs and proto-oncogene stabilization (2003) (345)
- Dichotomous effects of VEGF-A on adipose tissue dysfunction (2012) (336)
- Regulation of resistin expression and circulating levels in obesity, diabetes, and fasting. (2004) (332)
- Consuming fructose-sweetened beverages increases body adiposity in mice. (2005) (326)
- Role of caveolin-1 in the modulation of lipolysis and lipid droplet formation. (2004) (322)
- Constitutive and growth factor-regulated phosphorylation of caveolin-1 occurs at the same site (Tyr-14) in vivo: identification of a c-Src/Cav-1/Grb7 signaling cassette. (2000) (319)
- Caveolin-1 Gene Disruption Promotes Mammary Tumorigenesis and Dramatically Enhances Lung Metastasis in Vivo (2004) (304)
- Induction of adipocyte complement-related protein of 30 kilodaltons by PPARgamma agonists: a potential mechanism of insulin sensitization. (2002) (299)
- Fat apoptosis through targeted activation of caspase 8: a new mouse model of inducible and reversible lipoatrophy (2005) (298)
- Spliced X-Box Binding Protein 1 Couples the Unfolded Protein Response to Hexosamine Biosynthetic Pathway (2014) (295)
- The adipocyte as an endocrine cell. (2008) (289)
- Secretion of the Adipocyte-Specific Secretory Protein Adiponectin Critically Depends on Thiol-Mediated Protein Retention (2007) (287)
- Mitochondrial dysfunction in white adipose tissue (2012) (283)
- Paracrine and endocrine effects of adipose tissue on cancer development and progression. (2011) (280)
- MitoNEET-driven alterations in adipocyte mitochondrial activity reveal a crucial adaptive process that preserves insulin sensitivity in obesity (2012) (273)
- Diabetes and apoptosis: lipotoxicity (2009) (269)
- Adipocyte-derived endotrophin promotes malignant tumor progression. (2012) (266)
- Hyperglycemia-induced Production of Acute Phase Reactants in Adipose Tissue* (2001) (262)
- A Proteomic Approach for Identification of Secreted Proteins during the Differentiation of 3T3-L1 Preadipocytes to Adipocytes* (2002) (261)
- Targeted Induction of Ceramide Degradation Leads to Improved Systemic Metabolism and Reduced Hepatic Steatosis. (2015) (254)
- Mechanisms of early insulin-sensitizing effects of thiazolidinediones in type 2 diabetes. (2004) (245)
- Hepatocyte Toll-like Receptor 4 Regulates Obesity-Induced Inflammation and Insulin Resistance (2014) (241)
- Myofibroblasts in Murine Cutaneous Fibrosis Originate From Adiponectin‐Positive Intradermal Progenitors (2015) (237)
- Adiponectin: Systemic contributor to insulin sensitivity (2003) (235)
- Endotrophin triggers adipose tissue fibrosis and metabolic dysfunction (2014) (233)
- Role of caveolin and caveolae in insulin signaling and diabetes. (2003) (230)
- Adiponectin, driver or passenger on the road to insulin sensitivity? (2013) (226)
- Adiponectin, Cardiovascular Function, and Hypertension (2008) (226)
- An Endothelial-to-Adipocyte Extracellular Vesicle Axis Governed by Metabolic State (2018) (225)
- Plasma adiponectin complexes have distinct biochemical characteristics. (2008) (223)
- Genetic Ablation of Caveolin-1 Confers Protection Against Atherosclerosis (2004) (223)
- Mechanisms of obesity and related pathologies: The macro‐ and microcirculation of adipose tissue (2009) (221)
- Hyperglycemia as a Risk Factor for Cancer Progression (2014) (219)
- Expression of Caveolin-1 Is Required for the Transport of Caveolin-2 to the Plasma Membrane (1999) (218)
- Cyclin D1 Repression of Peroxisome Proliferator-Activated Receptor γ Expression and Transactivation (2003) (214)
- Adiponectin in health and disease: evaluation of adiponectin-targeted drug development strategies. (2009) (213)
- Disulfide-Dependent Multimeric Assembly of Resistin Family Hormones (2004) (213)
- Caveolin-2 Localizes to the Golgi Complex but Redistributes to Plasma Membrane, Caveolae, and Rafts when Co-expressed with Caveolin-1* (1999) (209)
- The Role of Adipocytes and Adipocyte‐Like Cells in the Severity of COVID‐19 Infections (2020) (204)
- A precursor protein partly translocated into yeast mitochondria is bound to a 70 kd mitochondrial stress protein. (1990) (202)
- Xbp1s in Pomc neurons connects ER stress with energy balance and glucose homeostasis. (2014) (201)
- Obese adipocytes show ultrastructural features of stressed cells and die of pyroptosis (2013) (200)
- Adiponectin complexes in human cerebrospinal fluid: distinct complex distribution from serum (2007) (197)
- Selective Downregulation of the High–Molecular Weight Form of Adiponectin in Hyperinsulinemia and in Type 2 Diabetes (2007) (194)
- Selective Inhibition of Hypoxia-Inducible Factor 1α Ameliorates Adipose Tissue Dysfunction (2012) (192)
- The Adipocyte as an Important Target Cell for Trypanosoma cruzi Infection* (2005) (189)
- Expression of caveolin-1 and -2 in differentiating PC12 cells and dorsal root ganglion neurons: caveolin-2 is up-regulated in response to cell injury. (1998) (180)
- Molecular genetics of the caveolin gene family: implications for human cancers, diabetes, Alzheimer disease, and muscular dystrophy. (1998) (179)
- C/EBPα and the Corepressors CtBP1 and CtBP2 Regulate Repression of Select Visceral White Adipose Genes during Induction of the Brown Phenotype in White Adipocytes by Peroxisome Proliferator-Activated Receptor γ Agonists (2009) (176)
- Adipocyte differentiation induces dynamic changes in NF-kappaB expression and activity. (2004) (174)
- Crowded little caves: structure and function of caveolae. (1998) (174)
- Systemic Fate of the Adipocyte-Derived Factor Adiponectin (2009) (172)
- ACDC/adiponectin polymorphisms are associated with severe childhood and adult obesity. (2006) (170)
- Specific Hepatic Sphingolipids Relate to Insulin Resistance, Oxidative Stress, and Inflammation in Nonalcoholic Steatohepatitis (2018) (166)
- Inner membrane protease I, an enzyme mediating intramitochondrial protein sorting in yeast. (1991) (162)
- Loss of Resistin Improves Glucose Homeostasis in Leptin Deficiency (2006) (158)
- A Role for the Caveolin Scaffolding Domain in Mediating the Membrane Attachment of Caveolin-1 (1999) (156)
- Adiponectin: a relevant player in PPARγ-agonist-mediated improvements in hepatic insulin sensitivity? (2005) (156)
- Adiponectin suppresses gluconeogenic gene expression in mouse hepatocytes independent of LKB1-AMPK signaling. (2011) (155)
- Metabolically healthy and unhealthy obese – the 2013 Stock Conference report (2014) (154)
- The transcriptional response of the islet to pregnancy in mice. (2009) (152)
- Chronic intermittent hypoxia induces atherosclerosis via activation of adipose angiopoietin-like 4. (2013) (151)
- Altered mitochondrial function and metabolic inflexibility associated with loss of caveolin-1. (2012) (148)
- Keynote review: the adipocyte as a drug discovery target. (2005) (148)
- Caveolae, transmembrane signalling and cellular transformation. (1995) (147)
- Proangiogenic Contribution of Adiponectin toward Mammary Tumor Growth In vivo (2009) (147)
- Enhanced metabolic flexibility associated with elevated adiponectin levels. (2010) (146)
- Cell type-specific expression and coregulation of murine resistin and resistin-like molecule-α in adipose tissue (2002) (146)
- Cab45, a novel (Ca2+)-binding protein localized to the Golgi lumen (1996) (146)
- Brain Adipocytokine Action and Metabolic Regulation (2006) (145)
- The delicate balance between fat and muscle: adipokines in metabolic disease and musculoskeletal inflammation. (2004) (143)
- Targeted Down-regulation of Caveolin-3 Is Sufficient to Inhibit Myotube Formation in Differentiating C2C12 Myoblasts (1999) (142)
- An Adipose Tissue Atlas: An Image-Guided Identification of Human-like BAT and Beige Depots in Rodents. (2018) (139)
- A Dominant-negative p38 MAPK Mutant and Novel Selective Inhibitors of p38 MAPK Reduce Insulin-stimulated Glucose Uptake in 3T3-L1 Adipocytes without Affecting GLUT4 Translocation* (2002) (139)
- Identification and characterization of a promoter cassette conferring adipocyte-specific gene expression. (2010) (138)
- Adiponectin is critical in determining susceptibility to depressive behaviors and has antidepressant-like activity (2012) (138)
- Adipocyte, Adipose Tissue, and Infectious Disease (2006) (137)
- Hypoadiponectinaemia and high risk of type 2 diabetes are associated with adiponectin-encoding (ACDC) gene promoter variants in morbid obesity: evidence for a role of ACDC in diabesity (2005) (135)
- Obesity, Diabetes, and Cardiovascular Diseases: A Compendium. (2016) (134)
- Adipokines linking obesity with colorectal cancer risk in postmenopausal women. (2012) (134)
- Partial Leptin Reduction as an Insulin Sensitization and Weight Loss Strategy. (2019) (134)
- Mechanisms of Trypanosoma cruzi persistence in Chagas disease (2012) (133)
- Cloning of cell-specific secreted and surface proteins by subtractive antibody screening (1998) (133)
- Beyond adiponectin and leptin: adipose tissue-derived mediators of inter-organ communication (2019) (133)
- The Membrane-spanning Domains of Caveolins-1 and -2 Mediate the Formation of Caveolin Hetero-oligomers (1999) (132)
- Mutational analysis of caveolin‐induced vesicle formation (1998) (131)
- Beclin 2 Functions in Autophagy, Degradation of G Protein-Coupled Receptors, and Metabolism (2013) (130)
- Inducible overexpression of adiponectin receptors highlight the roles of adiponectin-induced ceramidase signaling in lipid and glucose homeostasis (2017) (129)
- Adiponectin promotes functional recovery after podocyte ablation. (2013) (128)
- Adiponectin levels and genotype: a potential regulator of life span in humans. (2008) (127)
- Adiponectin and Leptin Levels in HIV‐Infected Subjects With Insulin Resistance and Body Fat Redistribution (2002) (126)
- Tumor Necrosis Factor α-Mediated Insulin Resistance, but Not Dedifferentiation, Is Abrogated by MEK1/2 Inhibitors in 3T3-L1 Adipocytes (2000) (125)
- microRNA-17 family promotes polycystic kidney disease progression through modulation of mitochondrial metabolism (2017) (124)
- A link between inflammation and metastasis: serum amyloid A1 and A3 induce metastasis, and are targets of metastasis-inducing S100A4 (2014) (124)
- Constitutively Active Mitogen-activated Protein Kinase Kinase 6 (MKK6) or Salicylate Induces Spontaneous 3T3-L1 Adipogenesis* (1999) (123)
- The Xbp1s/GalE axis links ER stress to postprandial hepatic metabolism. (2013) (123)
- Mitochondrial Functional State in Clonal Pancreatic β-Cells Exposed to Free Fatty Acids* (2003) (123)
- Molecular and cellular biology of caveolae paradoxes and plasticities. (1997) (122)
- Syndet is a novel SNAP-25 related protein expressed in many tissues. (1997) (120)
- Evidence for enhanced adipogenesis in the orbits of patients with Graves' ophthalmopathy. (2004) (118)
- Caveolae purification and glycosylphosphatidylinositol-linked protein sorting in polarized epithelia. (1995) (117)
- Targeted deletion of adipocytes by apoptosis leads to adipose tissue recruitment of alternatively activated M2 macrophages. (2011) (113)
- Weight loss and incretin responsiveness improve glucose control independently after gastric bypass surgery (2010) (111)
- Caveolin-3 knockout mice show increased adiposity and whole body insulin resistance, with ligand-induced insulin receptor instability in skeletal muscle. (2005) (110)
- Distinct Regulatory Mechanisms Govern Embryonic versus Adult Adipocyte Maturation (2015) (109)
- Identification of a 45-kDa protein at the protein import site of the yeast mitochondrial inner membrane. (1992) (109)
- Metabolic Messengers: adiponectin (2019) (109)
- Adipose tissue mass and location affect circulating adiponectin levels (2011) (108)
- Hypothalamic resistin induces hepatic insulin resistance. (2007) (107)
- ATR/TEM8 is highly expressed in epithelial cells lining Bacillus anthracis' three sites of entry: implications for the pathogenesis of anthrax infection. (2005) (106)
- Melanocortin 4 receptors in autonomic neurons regulate thermogenesis and glycemia (2014) (105)
- Brown adipose tissue derived VEGF-A modulates cold tolerance and energy expenditure (2014) (104)
- Evidence for Trypanosoma cruzi in adipose tissue in human chronic Chagas disease. (2011) (103)
- Immunologic and endocrine functions of adipose tissue: implications for kidney disease (2018) (103)
- Caveolin-1 and mitochondrial SOD2 (MnSOD) function as tumor suppressors in the stromal microenvironment (2011) (103)
- A Prospective Study of Inflammation Markers and Endometrial Cancer Risk in Postmenopausal Hormone Nonusers (2011) (102)
- Circulating Adipokines and Inflammatory Markers and Postmenopausal Breast Cancer Risk. (2015) (100)
- Mouse and Human Resistins Impair Glucose Transport in Primary Mouse Cardiomyocytes, and Oligomerization Is Required for This Biological Action* (2005) (99)
- 代謝：脂肪細胞ミトコンドリア活性のmitoNEETによる変化は、肥満時にインスリン感受性を維持するきわめて重要な適応過程を明らかにしている (2012) (98)
- The Pleiotropic Actions of Adiponectin are Initiated via Receptor-Mediated Activation of Ceramidase Activity (2010) (97)
- Adipocytes: impact on tumor growth and potential sites for therapeutic intervention. (2013) (97)
- Paradoxical Elevation of High–Molecular Weight Adiponectin in Acquired Extreme Insulin Resistance Due to Insulin Receptor Antibodies (2007) (96)
- Impact of tamoxifen on adipocyte lineage tracing: Inducer of adipogenesis and prolonged nuclear translocation of Cre recombinase (2015) (95)
- Adiponectin Resistance Exacerbates Insulin Resistance in Insulin Receptor Transgenic/Knockout Mice (2007) (94)
- Lipid metabolism and adipokine levels in fatty acid-binding protein null and transgenic mice. (2006) (93)
- The many secret lives of adipocytes: implications for diabetes (2018) (92)
- Low- and high-thermogenic brown adipocyte subpopulations coexist in murine adipose tissue. (2019) (92)
- Progressive loss of beta-cell function leads to worsening glucose tolerance in first-degree relatives of subjects with type 2 diabetes. (2007) (92)
- Grb10 promotes lipolysis and thermogenesis by phosphorylation-dependent feedback inhibition of mTORC1. (2014) (91)
- Plasma ceramides are elevated in female children and adolescents with type 2 diabetes (2013) (91)
- The Multifaceted Roles of Adipose Tissue—Therapeutic Targets for Diabetes and Beyond: The 2015 Banting Lecture (2016) (90)
- Selective enhancement of insulin sensitivity in the mature adipocyte is sufficient for systemic metabolic improvements (2015) (89)
- Optimization of protein production in mammalian cells with a coexpressed fluorescent marker. (2004) (89)
- Reversible De-differentiation of Mature White Adipocytes into Preadipocyte-like Precursors during Lactation. (2018) (89)
- Contributions of adipose tissue architectural and tensile properties toward defining healthy and unhealthy obesity. (2014) (88)
- Thromboxane A2 is a key regulator of pathogenesis during Trypanosoma cruzi infection (2007) (87)
- Extracellular vesicle-based interorgan transport of mitochondria from energetically stressed adipocytes. (2021) (87)
- 5-HT2CRs Expressed by Pro-opiomelanocortin Neurons Regulate Insulin Sensitivity in Liver (2010) (86)
- Adenovirus-mediated adiponectin expression augments skeletal muscle insulin sensitivity in male Wistar rats. (2005) (85)
- Differential Glucose Requirement in Skin Homeostasis and Injury Identifies a Therapeutic Target for Psoriasis (2018) (85)
- Cell type-specific expression and coregulation of murine resistin and resistin-like molecule-alpha in adipose tissue. (2002) (84)
- Combined Loss of INK4a and Caveolin-1 Synergistically Enhances Cell Proliferation and Oncogene-induced Tumorigenesis (2004) (84)
- Fasting selectively blocks development of acute lymphoblastic leukemia via leptin-receptor upregulation (2016) (84)
- Dermal Adipocytes: From Irrelevance to Metabolic Targets? (2016) (84)
- Src-induced Phosphorylation of Caveolin-2 on Tyrosine 19 (2002) (83)
- Hyperglycemia in rodent models of type 2 diabetes requires insulin-resistant alpha cells (2014) (82)
- Race-ethnic differences in adipokine levels: the Study of Women's Health Across the Nation (SWAN). (2012) (81)
- The Role of Proprotein Convertase Subtilisin/Kexin Type 9 in Nephrotic Syndrome-Associated Hypercholesterolemia (2016) (81)
- Leptin receptor signaling supports cancer cell metabolism through suppression of mitochondrial respiration in vivo. (2010) (80)
- MED13-dependent signaling from the heart confers leanness by enhancing metabolism in adipose tissue and liver (2014) (80)
- Fat-cell mass, serum leptin and adiponectin changes during weight gain and loss in yellow-bellied marmots (Marmota flaviventris) (2004) (79)
- Trypanosoma cruzi Utilizes the Host Low Density Lipoprotein Receptor in Invasion (2011) (79)
- An adipo-biliary-uridine axis that regulates energy homeostasis (2017) (79)
- Adiponectin, Leptin and Cardiovascular Disorders. (2021) (78)
- Dermal adipose tissue has high plasticity and undergoes reversible dedifferentiation in mice. (2019) (77)
- Adiponectin regulates contextual fear extinction and intrinsic excitability of dentate gyrus granule neurons through AdipoR2 receptors (2016) (76)
- Resistin, but Not Adiponectin and Leptin, Is Associated With the Risk of Ischemic Stroke Among Postmenopausal Women: Results From the Women's Health Initiative (2011) (76)
- A Role of the Inflammasome in the Low Storage Capacity of the Abdominal Subcutaneous Adipose Tissue in Obese Adolescents (2015) (76)
- Fat-Specific DsbA-L Overexpression Promotes Adiponectin Multimerization and Protects Mice From Diet-Induced Obesity and Insulin Resistance (2012) (76)
- Inhibition of endotrophin, a cleavage product of collagen VI, confers cisplatin sensitivity to tumours (2013) (73)
- Protein import into yeast mitochondria: the inner membrane import site protein ISP45 is the MPI1 gene product. (1993) (73)
- Cellular Origins of Beige Fat Cells Revisited (2019) (73)
- Chromosomal localization, expression pattern, and promoter analysis of the mouse gene encoding adipocyte-specific secretory protein Acrp30. (2001) (73)
- Adipose Tissue Biology and Cardiomyopathy: Translational Implications (2012) (72)
- Adiponectin is essential for lipid homeostasis and survival under insulin deficiency and promotes β-cell regeneration (2014) (72)
- Microarray analysis of changes in gene expression in a murine model of chronic chagasic cardiomyopathy (2003) (72)
- Improved methodologies for the study of adipose biology: insights gained and opportunities ahead (2014) (72)
- A CD36 nonsense mutation associated with insulin resistance and familial type 2 diabetes (2004) (71)
- Structure-guided Development of Specific Pyruvate Dehydrogenase Kinase Inhibitors Targeting the ATP-binding Pocket* (2013) (71)
- Tumor necrosis factor alpha-mediated insulin resistance, but not dedifferentiation, is abrogated by MEK1/2 inhibitors in 3T3-L1 adipocytes. (2000) (71)
- Connexin 43 Mediates White Adipose Tissue Beiging by Facilitating the Propagation of Sympathetic Neuronal Signals. (2016) (69)
- Ronning After the Adiponectin Receptors (2013) (69)
- Within-Individual Stability of Obesity-Related Biomarkers among Women (2007) (68)
- Trypanosoma cruzi Infection of Cultured Adipocytes Results in an Inflammatory Phenotype (2008) (67)
- Adipose Tissue: A Safe Haven for Parasites? (2017) (67)
- Morphogenesis of the developing mammary gland: stage-dependent impact of adipocytes. (2010) (67)
- Obese Mice Lacking Inducible Nitric Oxide Synthase Are Sensitized to the Metabolic Actions of Peroxisome Proliferator–Activated Receptor-γ Agonism (2008) (67)
- Adipocyte-Specific Deletion of Manganese Superoxide Dismutase Protects From Diet-Induced Obesity Through Increased Mitochondrial Uncoupling and Biogenesis (2016) (66)
- VEGF-A–Expressing Adipose Tissue Shows Rapid Beiging and Enhanced Survival After Transplantation and Confers IL-4–Independent Metabolic Improvements (2017) (66)
- Intracellular Trafficking and Secretion of Adiponectin Is Dependent on GGA-coated Vesicles* (2006) (65)
- Leptin and cancer: from cancer stem cells to metastasis. (2011) (65)
- Why does obesity cause diabetes? (2022) (64)
- Role of Transcription Factor NFAT in Glucose and Insulin Homeostasis (2006) (63)
- MitoNEET-Mediated Effects on Browning of White Adipose Tissue (2014) (63)
- PANIC-ATTAC: A Mouse Model for Inducible and Reversible β-Cell Ablation (2008) (63)
- Response of adipose tissue to early infection with Trypanosoma cruzi (Brazil strain). (2012) (63)
- In vitro phosphorylation of caveolin-rich membrane domains: identification of an associated serine kinase activity as a casein kinase II-like enzyme. (1994) (62)
- Obesity and diabetes as comorbidities for COVID-19: Underlying mechanisms and the role of viral–bacterial interactions (2020) (61)
- Analytical validation and biological evaluation of a high molecular-weight adiponectin ELISA. (2007) (60)
- Association of Phosphofructokinase-M with Caveolin-3 in Differentiated Skeletal Myotubes (1997) (59)
- Lack of Association Between Adiponectin Levels and Atherosclerosis in Mice (2010) (59)
- PPARγ in vagal neurons regulates high-fat diet induced thermogenesis. (2014) (57)
- HDAC11 suppresses the thermogenic program of adipose tissue via BRD2. (2018) (55)
- Relation of plasma ceramides to visceral adiposity, insulin resistance and the development of type 2 diabetes mellitus: the Dallas Heart Study (2018) (55)
- Adiponectin is an endogenous anti-fibrotic mediator and therapeutic target (2017) (55)
- Impact of simvastatin on adipose tissue: pleiotropic effects in vivo. (2009) (54)
- VGF ablation blocks the development of hyperinsulinemia and hyperglycemia in several mouse models of obesity. (2005) (53)
- Inflammation and ER stress regulate branched-chain amino acid uptake and metabolism in adipocytes. (2015) (52)
- Adipose tissue fatty acid chain length and mono-unsaturation increases with obesity and insulin resistance (2015) (52)
- Adiponectin: no longer the lone soul in the fight against insulin resistance? (2008) (52)
- Angiopoietin-2 in white adipose tissue improves metabolic homeostasis through enhanced angiogenesis (2017) (52)
- Adiponectin regulation of stellate cell activation via PPARγ-dependent and -independent mechanisms. (2011) (51)
- The Road From Discovery to Clinic: Adiponectin as a Biomarker of Metabolic Status (2009) (51)
- Proteinuria Increases Plasma Phosphate by Altering Its Tubular Handling. (2015) (51)
- Caveolin-1 expression is essential for proper nonshivering thermogenesis in brown adipose tissue. (2005) (51)
- Lipotoxicity and β Cell Maintenance in Obesity and Type 2 Diabetes (2019) (51)
- Pantophysin Is a Phosphoprotein Component of Adipocyte Transport Vesicles and Associates with GLUT4-containing Vesicles* (2000) (51)
- DsbA-L is a versatile player in adiponectin secretion (2008) (51)
- The primary sequence of murine caveolin reveals a conserved consensus site for phosphorylation by protein kinase C. (1994) (50)
- Nonneuronal expression of Rab3A: induction during adipogenesis and association with different intracellular membranes than Rab3D. (1995) (50)
- Effects of Adiponectin on Calcium-Handling Proteins in Heart Failure With Preserved Ejection Fraction (2014) (50)
- Prolactin Negatively Regulates Caveolin-1 Gene Expression in the Mammary Gland during Lactation, via a Ras-dependent Mechanism* (2001) (50)
- Adipocyte-Derived Factors Potentiate Nutrient-Induced Production of Plasminogen Activator Inhibitor–1 by Macrophages (2010) (50)
- Tenomodulin promotes human adipocyte differentiation and beneficial visceral adipose tissue expansion (2016) (49)
- Leptin: Less Is More (2020) (48)
- Skin aging: are adipocytes the next target? (2016) (48)
- Elevated resistin levels induce central leptin resistance and increased atherosclerotic progression in mice (2014) (48)
- High Fat Diet Modulates Trypanosoma cruzi Infection Associated Myocarditis (2014) (47)
- Adiponectin decreases pulmonary arterial remodeling in murine models of pulmonary hypertension. (2011) (47)
- Heart Failure With Preserved Ejection Fraction Induces Beiging in Adipose Tissue (2016) (47)
- The adipokine/ceramide axis: key aspects of insulin sensitization. (2014) (47)
- Human endotrophin as a driver of malignant tumor growth. (2019) (46)
- Adiponectin potentiates the acute effects of leptin in arcuate Pomc neurons (2016) (46)
- Cyclin D1 Restrains Oncogene-Induced Autophagy by Regulating the AMPK-LKB1 Signaling Axis. (2017) (46)
- Dermal adipocytes and hair cycling: is spatial heterogeneity a characteristic feature of the dermal adipose tissue depot? (2016) (46)
- Rgs16 and Rgs8 in embryonic endocrine pancreas and mouse models of diabetes (2010) (45)
- Mouse Models of Lipodystrophy Key reagents for the understanding of the metabolic syndrome. (2007) (45)
- Intermittent hypoxia exacerbates pancreatic β-cell dysfunction in a mouse model of diabetes mellitus. (2013) (45)
- The role of total and high-molecular-weight complex of adiponectin in vascular function in offspring whose parents both had type 2 diabetes (2005) (45)
- MitoNEET-Parkin Effects in Pancreatic α- and β-Cells, Cellular Survival, and Intrainsular Cross Talk (2016) (45)
- Adiponectin alters renal calcium and phosphate excretion through regulation of klotho expression. (2017) (44)
- Adiponectin as an independent predictor of the presence and degree of hepatic steatosis in the Dallas Heart Study. (2012) (43)
- Transcriptional Regulation of Dentin Matrix Protein 1 by JunB and p300 during Osteoblast Differentiation* (2004) (42)
- Phenotypic behavior of caveolin-3 R26Q, a mutant associated with hyperCKemia, distal myopathy, and rippling muscle disease. (2003) (42)
- The brown adipose tissue glucagon receptor is functional but not essential for control of energy homeostasis in mice (2019) (42)
- MKR mice are resistant to the metabolic actions of both insulin and adiponectin: discordance between insulin resistance and adiponectin responsiveness. (2006) (41)
- Chagas disease, adipose tissue and the metabolic syndrome. (2009) (41)
- Time course of histomorphological changes in adipose tissue upon acute lipoatrophy. (2013) (41)
- Adiponectin modulates ventral tegmental area dopamine neuron activity and anxiety-related behavior through AdipoR1 (2018) (40)
- Adiponectin-mediated antilipotoxic effects in regenerating pancreatic islets. (2015) (40)
- TRAIL (TNF-related apoptosis-inducing ligand) regulates adipocyte metabolism by caspase-mediated cleavage of PPARgamma (2013) (40)
- Differential Binding of Cross-Reactive Anti-DNA Antibodies to Mesangial Cells: The Role of α-Actinin1 (2006) (40)
- Endothelin in a Murine Model of Cerebral Malaria (2006) (40)
- MitoNEET-dependent formation of intermitochondrial junctions (2017) (39)
- Renal tubular cell spliced X-box binding protein 1 (Xbp1s) has a unique role in sepsis-induced acute kidney injury and inflammation. (2019) (39)
- Conditional MitoTimer reporter mice for assessment of mitochondrial structure, oxidative stress, and mitophagy (2017) (39)
- Thiazolidinediones improve insulin sensitivity in adipose tissue and reduce the hyperlipidaemia without affecting the hyperglycaemia in a transgenic model of type 2 diabetes (2004) (38)
- ERα upregulates Phd3 to ameliorate HIF-1 induced fibrosis and inflammation in adipose tissue (2014) (38)
- Effect of pioglitazone on plasma ceramides in adults with metabolic syndrome (2015) (38)
- Adipocytokine and ghrelin levels in relation to cardiovascular disease risk factors in women at midlife: longitudinal associations (2008) (38)
- Vascular Endothelial Growth Factor-D (VEGF-D) Overexpression and Lymphatic Expansion in Murine Adipose Tissue Improves Metabolism in Obesity. (2019) (37)
- Erratum: Mechanisms of early insulin-sensitizing effects of thiazolidinediones in type 2 diabetes (Diabetes (2004) 53 (1621-1629)) (2005) (37)
- Desalting electroeluted proteins with hydrophilic interaction chromatography. (1993) (37)
- Enhanced fatty acid flux triggered by adiponectin overexpression. (2012) (37)
- Purification of caveolae-derived membrane microdomains containing lipid-anchored signaling molecules, such as GPI-anchored proteins, H-Ras, Src-family tyrosine kinases, eNOS, and G-protein alpha-, beta-, and gamma-subunits. (1999) (37)
- Critical Role of Matrix Metalloproteinase 14 in Adipose Tissue Remodeling during Obesity (2020) (37)
- Suppressing adipocyte inflammation promotes insulin resistance in mice (2020) (37)
- Dysregulation of Amyloid Precursor Protein Impairs Adipose Tissue Mitochondrial Function and Promotes Obesity (2019) (36)
- Endotrophin – Linking Obesity with Aggressive Tumor Growth (2012) (36)
- Insulin-sensitizing effects of thiazolidinediones are not linked to adiponectin receptor expression in human fat or muscle. (2007) (36)
- Caveolae and human disease: functional roles in transcytosis, potocytosis, signalling and cell polarity (1995) (36)
- Partial leptin deficiency confers resistance to diet-induced obesity in mice (2020) (36)
- Lack of “immunological fitness” during fasting in metabolically challenged animals[S] (2012) (35)
- Adipose HIF-1α causes obesity by suppressing brown adipose tissue thermogenesis (2017) (34)
- PAQRs: A Counteracting Force to Ceramides? (2009) (33)
- The adipokine SAA3 is induced by interleukin‐1β in mouse adipocytes (2008) (33)
- Crucial role of the central leptin receptor in murine Trypanosoma cruzi (Brazil strain) infection. (2010) (33)
- Hepatocyte toll-like receptor 4 deficiency protects against alcohol-induced fatty liver disease (2018) (33)
- Neuregulin 1-HER axis as a key mediator of hyperglycemic memory effects in breast cancer (2012) (33)
- Hepatocyte Growth Factor and the Risk of Ischemic Stroke Developing Among Postmenopausal Women: Results From the Women's Health Initiative (2010) (32)
- Predominant expression of the mitochondrial dicarboxylate carrier in white adipose tissue. (1999) (32)
- Obesity, Diabetes, and Increased Cancer Progression (2021) (32)
- Short-Term Versus Long-Term Effects of Adipocyte Toll-Like Receptor 4 Activation on Insulin Resistance in Male Mice (2017) (32)
- Apoptosis Through Targeted Activation of Caspase8 (“ATTAC-mice”): Novel Mouse Models of Inducible and Reversible Tissue Ablation (2005) (32)
- Cyclin and Caveolin Expression in an Acute Model of Murine Chagasic Myocarditis (2006) (31)
- SREBP-regulated adipocyte lipogenesis is dependent on substrate availability and redox modulation of mTORC1. (2019) (31)
- Obesity dysregulates fasting-induced changes in glucagon secretion. (2019) (31)
- Phosphofructokinase muscle-specific isoform requires caveolin-3 expression for plasma membrane recruitment and caveolar targeting: implications for the pathogenesis of caveolin-related muscle diseases. (2003) (31)
- Alterations in glucose homeostasis in a murine model of Chagas disease. (2013) (31)
- Adipocyte Xbp1s overexpression drives uridine production and reduces obesity (2018) (31)
- Diffuse vesicular distribution of Rab3D in the polarized neuroendocrine cell line AtT‐20 (1995) (30)
- Associations of testosterone and sex hormone binding globulin with adipose tissue hormones in midlife women (2012) (30)
- Intracellular lipid metabolism impairs &bgr; cell compensation during diet-induced obesity (2018) (30)
- Acute loss of adipose tissue-derived adiponectin triggers immediate metabolic deterioration in mice (2018) (30)
- Skin aging as a mechanical phenomenon: The main weak links (2018) (30)
- SF-1 expression in the hypothalamus is required for beneficial metabolic effects of exercise (2016) (29)
- Hyaluronan in adipogenesis, adipose tissue physiology and systemic metabolism (2018) (29)
- Adipocytes in both brown and white adipose tissue of adult mice are functionally connected via gap junctions: implications for Chagas disease. (2014) (29)
- The Role of Immature and Mature Adipocytes in Hair Cycling (2019) (29)
- Dichotomous roles of leptin and adiponectin as enforcers against lipotoxicity during feast and famine (2013) (28)
- Molecular cloning and developmental expression of the caveolin gene family in the amphibian Xenopus laevis. (2002) (28)
- Ceramides and cardiac function in children with chronic kidney disease (2014) (28)
- The AdipoChaser mouse (2014) (28)
- Glucagon blockade restores functional β-cell mass in type 1 diabetic mice and enhances function of human islets (2021) (27)
- The anatomical basis for wrinkles. (2014) (27)
- Glucose-regulated protein 78 is essential for cardiac myocyte survival (2018) (27)
- XBP1S Regulates MUC5B in a Promoter Variant-Dependent Pathway in IPF Airway Epithelia. (2019) (27)
- Adipose tissue, diabetes and Chagas disease. (2011) (27)
- Compromised responses to dietary methionine restriction in adipose tissue but not liver of ob/ob mice (2015) (27)
- Serum Amyloid A3 Gene Expression in Adipocytes is an Indicator of the Interaction with Macrophages (2016) (26)
- Endotrophin, a multifaceted player in metabolic dysregulation and cancer progression, is a predictive biomarker for the response to PPARγ agonist treatment (2016) (26)
- E4orf1 induction in adipose tissue promotes insulin-independent signaling in the adipocyte (2015) (26)
- Hyaluronan in adipose tissue: Beyond dermal filler and therapeutic carrier (2016) (26)
- Adipocyte iron levels impinge on a fat-gut crosstalk to regulate intestinal lipid absorption and mediate protection from obesity. (2021) (25)
- Evolutionarily Conserved Role of Calcineurin in Phosphodegron-Dependent Degradation of Phosphodiesterase 4D (2010) (25)
- Dapagliflozin suppresses glucagon signaling in rodent models of diabetes (2017) (25)
- Preexisting and inducible endotoxemia as crucial contributors to the severity of COVID-19 outcomes (2021) (25)
- Serum adiponectin is related to plasma high-density lipoprotein cholesterol but not to plasma insulin-concentration in healthy children: the FLVS II study. (2006) (25)
- A Novel Model of Diabetic Complications: Adipocyte Mitochondrial Dysfunction Triggers Massive β-Cell Hyperplasia (2019) (24)
- Markers of oxidative stress in adipose tissue during Trypanosoma cruzi infection (2014) (24)
- Peroxisome Proliferator-Activated Receptor γ and Its Role in Adipocyte Homeostasis and Thiazolidinedione-Mediated Insulin Sensitization (2018) (24)
- Mitochondrial metabolism is a key regulator of the fibro-inflammatory and adipogenic stromal subpopulations in white adipose tissue. (2021) (24)
- Adiponectin and cardiovascular risk profile in patients with type 2 diabetes mellitus: parameters associated with adiponectin complex distribution (2011) (23)
- A feed-forward regulatory loop in adipose tissue promotes signaling by the hepatokine FGF21 (2020) (22)
- Caveolin-1 in skin aging – From innocent bystander to major contributor (2019) (22)
- Caveolin-1 as a pathophysiological factor and target in psoriasis (2019) (22)
- Lumenal protein sorting to the constitutive secretory pathway of a regulated secretory cell (2006) (22)
- Adiponectin protects against incident hypertension independent of body fat distribution: observations from the Dallas Heart Study (2017) (21)
- Role of Extracellular Signal-regulated Kinase 5 in Adipocyte Signaling* (2014) (21)
- Post-acute sequelae of COVID-19: A metabolic perspective (2022) (21)
- COL6A3‐derived endotrophin links reciprocal interactions among hepatic cells in the pathology of chronic liver disease (2018) (21)
- The Role of Ceramides in Diabetes and Cardiovascular Disease Regulation of Ceramides by Adipokines (2020) (21)
- Spliced X-Box Binding Protein 1 Stimulates Adaptive Growth Through Activation of mTOR. (2019) (21)
- Glucagon therapeutics: Dawn of a new era for diabetes care (2016) (20)
- Are dermal adipocytes involved in psoriasis? (2016) (20)
- Lowering ceramides to overcome diabetes (2019) (20)
- Adiponectin preserves metabolic fitness during aging (2021) (20)
- A novel ADIPOQ mutation (p.M40K) impairs assembly of high-molecular-weight adiponectin and is associated with early-onset obesity and metabolic syndrome. (2014) (20)
- Mechanisms regulating repression of haptoglobin production by peroxisome proliferator-activated receptor-gamma ligands in adipocytes. (2010) (20)
- PAQ receptors: a counteracting force to ceramides? (2009) (20)
- Adipocyte Gs but not Gi signaling regulates whole-body glucose homeostasis (2019) (20)
- Serum adiponectin complexes and cardiovascular risk in children with chronic kidney disease (2011) (20)
- The mitochondrial dicarboxylate carrier prevents hepatic lipotoxicity by inhibiting white adipocyte lipolysis. (2021) (20)
- Dietary n-3 polyunsaturated fatty acids fail to reduce prostate tumorigenesis in the PB-ErbB-2 x Pten(+/-) preclinical mouse model. (2010) (19)
- Adiponectin, an adipocyte-derived hepatic insulin sensitizer regulation during development. (2004) (19)
- Intercellular and interorgan crosstalk through adipocyte extracellular vesicles (2021) (19)
- Caveolin-1 as a target in prevention and treatment of hypertrophic scarring (2019) (19)
- Adipose tissue biology in 2014: Advances in our understanding of adipose tissue homeostasis (2015) (18)
- Adipocyte‐myofibroblast transition as a possible pathophysiological step in androgenetic alopecia (2017) (18)
- Adipose tissue: The dysfunctional adipocyte — a cancer cell's best friend (2018) (18)
- Maternal adiponectin controls milk composition to prevent neonatal inflammation. (2015) (18)
- Adipose Tissue Dysfunction: A Multistep Process (2010) (18)
- The impact of endotrophin on the progression of chronic liver disease (2020) (17)
- Ablation of Calcineurin Aβ Reveals Hyperlipidemia and Signaling Cross-talks with Phosphodiesterases* (2012) (17)
- General theory of skin reinforcement (2017) (17)
- Differential transendothelial transport of adiponectin complexes (2014) (16)
- Sex differences in adult rat insulin and glucose responses to arginine: programming effects of neonatal separation, hypoxia, and hypothermia (2016) (16)
- Retrograde Lymph Flow Leads to Chylothorax in Transgenic Mice with Lymphatic Malformations. (2017) (16)
- Loss of the liver X receptor LXRα/β in peripheral sensory neurons modifies energy expenditure (2015) (16)
- Peroxisome proliferator‐activated receptor γ agonists inhibit adipocyte expression of α1‐acid glycoprotein (2007) (15)
- Role of ceramide-to-dihydroceramide ratios for insulin resistance and non-alcoholic fatty liver disease in humans (2020) (15)
- Hepatic GALE Regulates Whole-Body Glucose Homeostasis by Modulating Tff3 Expression (2017) (15)
- Integrated Stress Response Couples Mitochondrial Protein Translation with Oxidative Stress Control. (2021) (14)
- Relationship between Changes in Plasma Adiponectin Concentration and Insulin Sensitivity after Niacin Therapy (2012) (14)
- Adiponectin: Just Along for the Ride? (2016) (14)
- The PPARγ-FGF1 axis: an unexpected mediator of adipose tissue homeostasis (2012) (14)
- Analysis of compensatory beta-cell response in mice with combined mutations of Insr and Irs2. (2007) (14)
- Cannabinoid receptor-1 signaling in hepatocytes and stellate cells does not contribute to NAFLD. (2021) (14)
- Loss of Tbk1 kinase activity protects mice from diet-induced metabolic dysfunction (2018) (14)
- Klotho regulation by albuminuria is dependent on ATF3 and endoplasmic reticulum stress (2019) (13)
- Grb 10 Promotes Lipolysis and Thermogenesis by Phosphorylation-Dependent Feedback Inhibition of mTORC 1 (2014) (13)
- Remodeling of Murine Mammary Adipose Tissue during Pregnancy, Lactation, and Involution (2019) (13)
- Dermal adipocytes contribute to the metabolic regulation of dermal fibroblasts (2020) (13)
- Nav1.8 neurons are involved in limiting acute phase responses to dietary fat (2017) (13)
- Adiponectin Moderates Antidepressant Treatment Outcome in the Combining Medications to Enhance Depression Outcomes Randomized Clinical Trial. (2018) (13)
- PKM1 Exerts Critical Roles in Cardiac Remodeling Under Pressure Overload in the Heart (2021) (12)
- Endotrophin in the tumor stroma: a new therapeutic target for breast cancer? (2013) (12)
- Thromboxane A 2 is a key regulator of pathogenesis during Trypanosoma cruzi infection (2007) (12)
- Autonomous interconversion between adult pancreatic α-cells and β-cells after differential metabolic challenges (2016) (12)
- Gender differences in adiponectin modulation of cardiac remodeling in mice deficient in endothelial nitric oxide synthase (2012) (12)
- Characterization of ALTO-encoding circular RNAs expressed by Merkel cell polyomavirus and trichodysplasia spinulosa polyomavirus (2021) (11)
- The cover. Neuroendocrine and endocrine pathways of obesity. (2012) (11)
- Adiponectin/Acrp30, an adipocyte‐specific secretory factor: physiological relevance during development (2003) (11)
- Structural biology: Receptors grease the metabolic wheels (2017) (11)
- Caveolin‐1 as a possible target in the treatment for acne (2019) (11)
- Caveolin as a Universal Target in Dermatology (2019) (11)
- The MMP14–caveolin axis and its potential relevance for lipoedema (2020) (11)
- Imaging Metabolically Active Fat: A Literature Review and Mechanistic Insights (2019) (11)
- New zoning laws enforced by glucagon (2018) (11)
- The metabolic syndrome, thiazolidinediones, and implications for intersection of chronic and inflammatory disease (2021) (10)
- Adiponectin and cardiometabolic trait and mortality: where do we go? (2021) (10)
- XBP1S Regulates MUC5B in a Promoter Variant – Dependent Pathway in Idiopathic Pulmonary Fibrosis Airway Epithelia (2019) (10)
- Adiponectin: basic and clinical aspects. Preface. (2014) (10)
- Utility of Adipocyte Fractions in Fat Grafting in an Athymic Rat Model (2018) (10)
- Fat tissue regulates the pathogenesis and severity of cardiomyopathy in murine chagas disease (2020) (9)
- Keystone meeting summary: 'Adipogenesis, obesity, and inflammation' and 'Diabetes mellitus and the control of cellular energy metabolism, ' January 21-26, 2006, Vancouver, Canada. (2006) (9)
- Mouse Adipose Tissue Protein Extraction (2020) (9)
- Perspectives on Adipose Tissue, Chagas Disease and Implications for the Metabolic Syndrome (2009) (9)
- Adipocyte mesenchymal transition contributes to mammary tumor progression (2022) (9)
- Mitochondrial regulation and white adipose tissue homeostasis. (2021) (8)
- A Prospective Analysis of Plasma Adiponectin and Risk of Incident Cancer: The Dallas Heart Study. (2015) (8)
- Adipose tissue hyaluronan production improves systemic glucose homeostasis and primes adipocytes for CL 316,243-stimulated lipolysis (2021) (8)
- ATF4 Protects the Heart From Failure by Antagonizing Oxidative Stress (2022) (7)
- Leptin beyond the lipostat: key component of blood pressure regulation. (2015) (7)
- Fibrosis—streaks and splatters: Some things are not always what they seem to be (2016) (7)
- Alterations in pancreatic β cell function and Trypanosoma cruzi infection: evidence from human and animal studies (2017) (7)
- Pathological Type-2 Immune Response, Enhanced Tumor Growth, and Glucose Intolerance in Retnlβ (RELMβ) Null Mice: A Model of Intestinal Immune System Dysfunction in Disease Susceptibility. (2016) (7)
- Isolation and quantitation of adiponectin higher order complexes. (2014) (7)
- Impact of the loss of caveolin-1 on lung mass and cholesterol metabolism in mice with and without the lysosomal cholesterol transporter, Niemann-Pick type C1. (2014) (6)
- Peroxisome proliferator-activated receptor gamma agonists inhibit adipocyte expression of alpha1-acid glycoprotein. (2007) (6)
- Adiponectin-SOGA Dissociation in Type 1 Diabetes. (2015) (6)
- Regulation of cold-induced thermogenesis by the RNA binding protein FAM195A (2021) (6)
- Cross-linking reagents as tools for identifying components of the yeast mitochondrial protein import machinery. (1991) (6)
- Cyclin D 1 Restrains Oncogene-Induced Autophagy by Regulating the AMPK-LKB 1 Signaling Axis (2018) (6)
- PEGylated AdipoRon derivatives improve glucose and lipid metabolism under insulinopenic and high-fat diet conditions (2021) (6)
- Elevated adiponectin prevents HIV protease inhibitor toxicity and preserves cerebrovascular homeostasis in mice. (2016) (6)
- PPARγ and its Role in Adipocyte Homeostasis and Thiazolidinedione-Mediated Insulin Sensitization. (2018) (5)
- Myofibroblasts in Cutaneous Fibrosis Originate from Adiponectin-Positive Intradermal Progenitors Running Head: Adipocytemyofibroblast transition (AMT) in skin fibrosis (2014) (5)
- Adult pancreatic islet endocrine cells emerge as fetal hormone-expressing cells (2022) (5)
- ERRATUM: Adiponectin acts in the brain to decrease body weight (2004) (5)
- Golgi-Localized PAQR4 Mediates Antiapoptotic Ceramidase Activity in Breast Cancer (2020) (5)
- Induction of Effective Immunity against Trypanosoma cruzi (2020) (5)
- Erratum: Adipose tissue fatty acid chain length and mono-unsaturation increases with obesity and insulin resistance (2016) (4)
- MitoNEET, a key regulator of mitochondrial function and lipid homeostasis (2012) (4)
- In Vivo ZIMIR Imaging of Mouse Pancreatic Islet Cells Shows Oscillatory Insulin Secretion (2021) (4)
- Metabolic jet lag when the fat clock is out of sync (2012) (4)
- Overexpression of ST5, an activator of Ras, has no effect on β-cell proliferation in adult mice (2018) (4)
- Corrigendum: Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis (2013) (4)
- Fat-Speci fi c DsbA-L Overexpression Promotes Adiponectin Multimerization and Protects Mice From Diet-Induced Obesity and Insulin Resistance (2012) (4)
- Endotrophin: Nominated for best supporting actor in the fibro-inflammatory saga (2021) (3)
- Tissue-specific disruption of Kbtbd2 uncovers adipocyte-intrinsic and -extrinsic features of the teeny lipodystrophy syndrome (2020) (3)
- Systemic Fate of the Adipocyte-Derived Factor (2009) (3)
- Quantitative phosphoproteomic analyses identify STK11IP as a lysosome-specific substrate of mTORC1 that regulates lysosomal acidification (2021) (3)
- VEGF-A-Expressing Adipose Tissue Shows Rapid Beiging, Enhanced Survival after Transplantation (2018) (3)
- Adipose tissue macrophages exert systemic metabolic control by manipulating local iron concentrations (2022) (3)
- Skin aging: Dermal adipocytes metabolically reprogram dermal fibroblasts (2021) (3)
- Lipotoxicity and b Cell Maintenance in Obesity and Type 2 Diabetes (2019) (3)
- Adiponectin levels and genotype (2008) (3)
- Obesity: Slim without the gym — the magic of chilling out (2016) (3)
- Use and Applications of Subtractive Antibody Screening (2000) (3)
- Critical lipids link breastfeeding to healthy adipose tissue in infancy and adulthood. (2019) (3)
- Deficient Caveolin-1 Synthesis in Adipocytes Stimulates Systemic Insulin-independent Glucose Uptake via Extracellular Vesicles. (2022) (2)
- Activating Connexin43 gap junctions primes adipose tissue for therapeutic intervention (2022) (2)
- Nonneuronal expression of Rab 3 A : Induction during adipogenesis and association with different intracellular membranes than Rab 3 (2005) (2)
- From friend to foe: Pro-apoptotic action of nuclear ARC in diabetes. (2021) (2)
- β1 Syntrophin Supports Autophagy Initiation and Protects against Cerulein-Induced Acute Pancreatitis. (2019) (2)
- Epigenetic regulation of cardiometabolic disease by HDAC-BET association (2018) (2)
- Reduced oxygen consumption by fat cells improves metabolic defects (2018) (2)
- Human Beige Adipocytes: Epiphenomenon or Drivers of Metabolic Improvements? (2016) (2)
- Serum levels of endotrophin are associated with nonalcoholic steatohepatitis (2021) (2)
- Author response: Angiopoietin-2 in white adipose tissue improves metabolic homeostasis through enhanced angiogenesis (2017) (2)
- Antidiabetes wars: a new hope (2010) (2)
- Obese mice lacking iNOS are sensitized to the metabolic actions of PPAR γ agonism (2008) (2)
- Arid1a loss potentiates pancreatic β-cell regeneration through activation of EGF signaling (2020) (2)
- Author response: SF-1 expression in the hypothalamus is required for beneficial metabolic effects of exercise (2016) (2)
- Adiponectin predicts incident hypertension independent of body fat accumulation; observations from the dallas heart study (2016) (2)
- Pas de Deux: Glucagon and Thyroid Hormone Moving in Perfect Synchrony. (2017) (1)
- TLR4-Induced Local Adipose Inflammation Critically Regulates Glucose Homeostasis (2018) (1)
- MINIREVIEW Adipocyte, Adipose Tissue, and Infectious Disease (cid:1) (2007) (1)
- Phenotypical Conversions of Dermal Adipocytes as Pathophysiological Steps in Inflammatory Cutaneous Disorders (2022) (1)
- Adiponectin Modulates Pulmonary Vascular Remodeling By Inhibiting Pulmonary Artery Smooth Muscle Cell Proliferation (2010) (1)
- ACRP30 Elevation in Sera of Transgenic Mice Results in Orbital Fat Proliferation and is Elevated in Patient's Sera with Graves' Disease and Ophthalmopathy: Further Insight Into Orbital Adipogenesis (2002) (1)
- Fasting and Glucose-Stimulated Changes in Plasma Glucagon in Pancreatic Cancer: Potential Biomarkers for Detection? (2019) (1)
- Fasting-Induced Changes in Glucagon Secretion Are Dysregulated in Obesity (2018) (1)
- Crosstalk Between Adipose Tissue and the Heart: An Update (2022) (1)
- Fabp4, a new player in the adipo-pancreatic axis (2014) (1)
- Abstract 11565: The Unfolded Protein Response Directly Activates the Hexosamine Biosynthetic Pathway to Protect the Heart From Ischemia/Reperfusion Injury (2013) (1)
- Editorial for the directed issue: "Metabolic pathways in cancer". (2011) (1)
- Metabolic Roles of Adiponectin (2013) (1)
- A tribute to Roger H. Unger (1924-2020). (2020) (1)
- PHOSPHO1 puts the breaks on thermogenesis in brown adipocytes (2020) (1)
- Rgs16 is an early marker for islet formation and beta cell expansion in diabetics (2010) (0)
- Extracellular Matrix (ECM) and Fibrosis in Adipose Tissue: Overview and Perspectives. (2023) (0)
- Table of Contents (1991) (0)
- Structure-Function Studies of the Adipocyte-secreted (2003) (0)
- The Adipokine Adiponectin Can Be Elevated in Graves’ Ophthalmopathy (2009) (0)
- The role of adiponectin in carbohydrate and lipid metabolism (2003) (0)
- Table of Contents (1993) (0)
- Plasma adiponectin to predict incident cancer in a large multiethnic population-based cohort study. (2013) (0)
- 315-OR: Two Brown Adipocyte Subpopulations with Distinct Thermogenic Activity Coexist and Undergo Dynamic Interconversions upon Changes in Environmental Temperature (2019) (0)
- Human Polyomavirus-Encoded Circular RNAs (2020) (0)
- Abstract SY28-01: Stromal contributions of adipocytes to cancer (2017) (0)
- P-4: Identification and cloning of adipocyte-specific secretory proteins (2009) (0)
- Differential glucose requirement in skin homeostasis and injury identifies a therapeutic target for psoriasis (2018) (0)
- Continuous Hypoxia Suppresses Adiponectin Secretion By Adipocytes Through Activation Of The Unfolded Protein Response (2011) (0)
- Association of adiponectin in patatin-like phospholipase domain-containing 3 (PNPLA3) associated hepatic steatosis. (2014) (0)
- Running Title : Adiponectin in Type B Insulin Resistance (2007) (0)
- for the pathogenesis of anthrax infection three sites of entry: implications Bacillus anthracis' ATR/TEM8 is highly expressed in epithelial cells lining (2005) (0)
- Crystal Structure of Resistin-like beta (2004) (0)
- Abstract MP65: Prospective Association Between Adiponectin Levels With Neurocognitive And Neuroimaging Outcomes: Findings From The Dallas Heart Study (2022) (0)
- Adiponectin is an endogenous anti-fibrotic mediator and therapeutic target (2017) (0)
- Hepatocyte Growth Factor and the Risk of Ischemic Stroke Developing Among Postmenopausal Women (2010) (0)
- Collagene vi et cancer (2005) (0)
- Abstract 327: Cardiac Regulation of Metabolic Homeostasis by Med13 (2013) (0)
- Author response: Adiponectin is essential for lipid homeostasis and survival under insulin deficiency and promotes β-cell regeneration (2014) (0)
- Markers of oxidative stress in adipose tissue during Trypanosoma cruzi infection (2014) (0)
- Crystal Structure of resisitin (2004) (0)
- 180-OR: Tissue-Specific Functions of PPARα Overexpression in Liver, Adipose, and Pancreatic ß Cells (2019) (0)
- LBSUN129 Adipose Tissue Analysis Toolkit (at-at): An Imagej Plugin For Automated Analysis Of Adipocyte Number, Size, And Pericellular Fibrosis In Histological Sections (2022) (0)
- Hepatocyte Toll-like receptor 4 regulates alcoholic fatty liver disease in mice (2018) (0)
- Author response: Adiponectin preserves metabolic fitness during aging (2021) (0)
- Endotrophin neutralization through targeted antibody treatment protects from renal fibrosis in a podocyte ablation model (2023) (0)
- Pharmacological Induction of Adiponectin by PPAR Agonism Does Not Prevent Atherosclerosis in Lean Mice (2010) (0)
- The Role of Adipose Tissue in Cardiovascular Pathophysiology (2023) (0)
- Microsoft Word-Cav-1 TS paper (2004) (0)
- Obesity and adiponectin (2015) (0)
- RGS::GFP expression in endocrine pancreas during development and regeneration (2009) (0)
- Ie treatment mti insulin sensitizers (2004) (0)
- PPAR gamma activation rapidly increases ACRP30 in non‐diabetic subjects (2003) (0)
- Author response: Loss of the liver X receptor LXRα/β in peripheral sensory neurons modifies energy expenditure (2015) (0)
- 316-OR: Suppressing Adipose Tissue Inflammation Promotes Insulin Resistance in Mice (2019) (0)
- Decision letter: Single cell analysis reveals immune cell–adipocyte crosstalk regulating the transcription of thermogenic adipocytes (2019) (0)
- Correction to: The role of fat on cardiomyopathy outcome in mouse models of chronic Trypanosoma cruzi infection (2020) (0)
- Thiazolidinediones’ Insulin-Sensitizing Properties Depend on Adiponectin-Mediated Reductions in Certain Ceramide Species (2018) (0)
- Molecular imaging shows that high fat diet decreases both glucose and lipid metabolism in brown adipose tissue in rodents (2016) (0)
- NIA0002 Novel role for adiponectin pathway in human skeletal muscle bioenergetics (2006) (0)
- Golgi-localized PAQR4 mediates Anti-apoptotic Ceramidase Activity in Breast Cancer (2019) (0)
- PMON280 Effect of Gender Affirming Hormone Therapy (GAHT) on Adipose Tissue Morphology and Metabolism in Transgender Individuals (2022) (0)
- The impact of adipocytes and adipose tissue on systemic metabolism (2022) (0)
- YIA 02-04 RELATIONSHIP BETWEEN LEPTIN AND INCIDENT HYPERTENSION; OBSERVATIONS FROM THE DALLAS HEART STUDY. (2016) (0)
- The Significance of Elevated Adiponectin in the Treatment of Type 2 Diabetes (2003) (0)
- Glucose-regulated protein 78 is essential for cardiac myocyte survival (2018) (0)
- JCB_201409063 1..12 (2015) (0)
- The apical sorting of glycosylphosphatidylinositol-linked proteins (1995) (0)
- 639 Metabolic reprogramming maintains skin integrity in the absence of glucose transport and identifies a therapeutic vulnerability in psoriasiform hyperplasia (2018) (0)
- Caveolin-1 as a target in prevention and treatment of hypertrophic scarring (2019) (0)
- ADIPOKINES – Significance for insulin Resistance and the Metabolic Syndrome (2006) (0)
- Adipose Tissue Is a Mediator of Inflammation and Innate Immunity (2005) (0)
- A new signal that shrinks fat (2022) (0)
- Purified precursor proteins for studying protein import into yeast mitochondria. (1991) (0)
- Alterations in pancreatic β cell function and Trypanosoma cruzi infection: evidence from human and animal studies (2016) (0)
- Metabolic Messengers: adiponectin (2019) (0)
- Localization of adiponectin at the plasma membrane in caveolae of human adipocytes (2012) (0)
- Pathophysiology of cellulite: Possible involvement of selective endotoxemia (2022) (0)
- Collagen remodeling leads to inflammation-free expansion of periprostatic adipose tissue and promotes prostate cancer progression (2023) (0)
- Short Title: Adipocytes MnSOD and Diet-Induced Obesity Full Title: Adipocyte-Specific Deletion of Manganese Superoxide Dismutase Protects from Diet-Induced Obesity Via Increased Mitochondrial Uncoupling and Biogenesis (2016) (0)
- Ceramide promotes PKC z activation and CD 36-mediated lipid uptake in the liver (2015) (0)
- Nonneuronal expression ofRab3A:Induction during adipogenesis andassociation withdifferent intracellular membranes (1995) (0)
- The effects of pioglitazone treatment on pancreatic cancer-related insulin resistance. (2017) (0)
- Role of Transcription Factor NFAT in Glucose and Insulin Homeostasis (cid:1) (2006) (0)
- Transendothelial Transport May Determine Adiponectin Oligomer Functions (2010) (0)
- Adipogenesis and metabolic health (2019) (0)
- Comparison of BMIPP-SPECT/CT to 18FDG-PET/CT for Imaging Brown or Browning Fat in a Preclinical Model (2022) (0)
- Targeting the Amyloid Precursor Protein (APP) to Mitochondria of White Adipose Tissues Triggers Mitochondrial Dysfunction and Obesity (2018) (0)
- Smas activation Wdnm 1-like , a new adipokine with a role in MMP-2 (2008) (0)
- 140-OR: Dermal Adipose Tissue—A Unique Fat Pad Undergoes Dynamic Changes by Reversible Dedifferentiation (2019) (0)
- Ceramides are early responders in metabolic syndrome development in rhesus monkeys (2021) (0)
- Response to Kunos et al. and Lotersztajn and Mallat (2022) (0)
- New key players in adipogenesis from GWAS ? Relevance of genes found associated with obesity in Genome Wide Association studies in human adipocytes (2011) (0)
- Adipose tissue in health and disease: why should we care? (2019) (0)
- PROTEIN COMPLEXES ’98 Molecular Genetics of the Caveolin Gene Family: Implications for Human Cancers, Diabetes, Alzheimer Disease, and Muscular Dystrophy (1998) (0)
- Reduced oxygen consumption by fat cells improves metabolic defects (2018) (0)
- Abstract 261: Robust Cardioprotection Afforded by a Previously Unrecognized Link between the Unfolded Protein Response and the Hexosamine Biosynthetic Pathway (2014) (0)
- Oligomeric structure ofcaveolin: Implications forcaveolae membraneorganization (1995) (0)
- Insulin sensitive human adipocytes for in vitro studies (2022) (0)
- Caveolin-1 as a pathophysiological factor and target in psoriasis (2019) (0)
- Small Peptide, Large Implications: Endotrophin in Heart Failure with Preserved Ejection Fraction. (2023) (0)
- Differential prediction of antidepressant treatment response via measurement of baseline adiponectin level: findings from the CO-MED randomized clinical trial (2019) (0)
- Adipose HIF-1α causes obesity by suppressing brown adipose tissue thermogenesis (2016) (0)
- Transgenic Mice Overexpressing Adiponectin Are Protected Against Insulin Resistance Induced By Intermittent Hypoxia (2010) (0)
- YIA 02-04 RELATIONSHIP BETWEEN LEPTIN AND INCIDENT HYPERTENSION; OBSERVATIONS FROM THE DALLAS HEART STUDY (2016) (0)
- Caveolae Implications for signalling and cellular transformation (1994) (0)
- HDAC11 Suppresses the Thermogenic Program of Adipose Tissue via BRD2 (2018) (0)
- ADIPOCYTE-DERIVED FACTORS: IMPACT ON HEALTHSPAN AND LIFESPAN (2022) (0)
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What Schools Are Affiliated With Philipp E. Scherer?
Philipp E. Scherer is affiliated with the following schools:
