Philippe Horvath
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Philippe Horvathbiology Degrees
Biology
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Molecular Biology
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Genetics
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Biology
Philippe Horvath's Degrees
- Bachelors Biology University of California, Berkeley
- Masters Genetics Stanford University
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Why Is Philippe Horvath Influential?
(Suggest an Edit or Addition)According to Wikipedia, Philippe Horvath is a French scientist working for DuPont Nutrition and Health. His work was integral to the development of CRISPR-Cas, a versatile biochemical method for targeted genetic engineering. For this work, he was awarded the 2015 Massry Prize along with Emmanuelle Charpentier and Jennifer Doudna, as well as the 2016 Canada Gairdner International Award, with his Massry co-laureates in addition to Feng Zhang, Rodolphe Barrangou, Anthony Fauci, and Frank Plummer.
Philippe Horvath's Published Works
Published Works
- CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes (2007) (4876)
- Cas9–crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria (2012) (2147)
- CRISPR/Cas, the Immune System of Bacteria and Archaea (2010) (2106)
- Evolution and classification of the CRISPR–Cas systems (2011) (2084)
- The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA (2010) (1869)
- An updated evolutionary classification of CRISPR–Cas systems (2015) (1822)
- Phage Response to CRISPR-Encoded Resistance in Streptococcus thermophilus (2007) (1147)
- Evolutionary classification of CRISPR–Cas systems: a burst of class 2 and derived variants (2019) (899)
- The Streptococcus thermophilus CRISPR/Cas system provides immunity in Escherichia coli (2011) (750)
- Diversity, Activity, and Evolution of CRISPR Loci in Streptococcus thermophilus (2007) (744)
- Cas3 is a single‐stranded DNA nuclease and ATP‐dependent helicase in the CRISPR/Cas immune system (2011) (371)
- Comparative analysis of CRISPR loci in lactic acid bacteria genomes. (2009) (280)
- In vitro reconstitution of Cascade‐mediated CRISPR immunity in Streptococcus thermophilus (2013) (228)
- Programmable RNA shredding by the type III-A CRISPR-Cas system of Streptococcus thermophilus. (2014) (228)
- A decade of discovery: CRISPR functions and applications (2017) (214)
- A Novel Pheromone Quorum-Sensing System Controls the Development of Natural Competence in Streptococcus thermophilus and Streptococcus salivarius (2009) (196)
- crRNA and tracrRNA guide Cas9-mediated DNA interference in Streptococcus thermophilus (2013) (192)
- CRISPR: new horizons in phage resistance and strain identification. (2012) (184)
- Comparison of the Complete Genome Sequences of Bifidobacterium animalis subsp. lactis DSM 10140 and Bl-04 (2009) (159)
- An anti-CRISPR from a virulent streptococcal phage inhibits Streptococcus pyogenes Cas9 (2017) (141)
- Analysis of the Lactobacillus casei supragenome and its influence in species evolution and lifestyle adaptation (2012) (137)
- Widespread anti-CRISPR proteins in virulent bacteriophages inhibit a range of Cas9 proteins (2018) (128)
- Persisting Viral Sequences Shape Microbial CRISPR-based Immunity (2012) (127)
- Phage mutations in response to CRISPR diversification in a bacterial population. (2013) (106)
- Phage-Induced Expression of CRISPR-Associated Proteins Is Revealed by Shotgun Proteomics in Streptococcus thermophilus (2012) (80)
- The fast milk acidifying phenotype of Streptococcus thermophilus can be acquired by natural transformation of the genomic island encoding the cell-envelope proteinase PrtS (2011) (76)
- Mobile CRISPR/Cas-Mediated Bacteriophage Resistance in Lactococcus lactis (2012) (72)
- Comparative Analyses of Prophage-Like Elements Present in Bifidobacterial Genomes (2009) (58)
- Complete coding sequence, deduced primary structure, chromosomal localization, and structural analysis of murine aggrecan. (1994) (54)
- PDP1, a novel Drosophila PAR domain bZIP transcription factor expressed in developing mesoderm, endoderm and ectoderm, is a transcriptional regulator of somatic muscle genes. (1997) (50)
- Evolutionary classification of CRISPR–Cas systems: a burst of class 2 and derived variants (2019) (50)
- Development of a Versatile Procedure Based on Natural Transformation for Marker-Free Targeted Genetic Modification in Streptococcus thermophilus (2010) (49)
- Evolution and classification of the CRISPR – Cas (2011) (48)
- Genomic impact of CRISPR immunization against bacteriophages. (2013) (47)
- Analysis of the type II-A CRISPR-Cas system of Streptococcus agalactiae reveals distinctive features according to genetic lineages (2015) (38)
- Multiple elements in the 5' untranslated region down-regulate c-sis messenger RNA translation. (1995) (27)
- The CRISPR System Protects Microbes against Phages, Plasmids Palindromic DNA repeat sequences immunize microorganisms against phages and plasmids, while also directing their evolution (2009) (25)
- RNA-guided genome editing à la carte (2013) (20)
- Widespread anti-CRISPR proteins in virulent bacteriophages inhibit a range of Cas9 proteins (2018) (20)
- Natural DNA Transformation Is Functional in Lactococcus lactis subsp. cremoris KW2 (2017) (18)
- CRISPR: A Useful Genetic Feature to Follow Vaginal Carriage of Group B Streptococcus (2017) (16)
- Dairy lactococcal and streptococcal phage-host interactions: an industrial perspective in an evolving phage landscape. (2020) (16)
- Lactobacillus herbarum sp. nov., a species related to Lactobacillus plantarum. (2015) (16)
- Novel Genus of Phages Infecting Streptococcus thermophilus: Genomic and Morphological Characterization (2020) (14)
- The compaction of mouse heterochromatin as studied by nuclease digestion (1981) (13)
- Rough and smooth morphotypes isolated from Lactobacillus farciminis CNCM I-3699 are two closely-related variants. (2015) (12)
- A mutation in the methionine aminopeptidase gene provides phage resistance in Streptococcus thermophilus (2019) (12)
- The CRISPR-Cas app goes viral. (2017) (6)
- Lactic Acid Bacteria Defenses Against Phages (2011) (5)
- Genomic and morphological characterization of a novel genus of phages infecting Streptococcus thermophilus. (2020) (5)
- Functional Study of the Type II-A CRISPR-Cas System of Streptococcus agalactiae Hypervirulent Strains. (2021) (3)
- Applications of the Versatile CRISPR-Cas Systems (2013) (3)
- Protection against Foreign DNA (2011) (3)
- Rodolphe Barrangou Prokaryotes CRISPR Provides Acquired Resistance Against Viruses in (2013) (2)
- Analysis of the Lactobacillus casei supragenome and its influence in species evolution and lifestyle adaptation (2012) (2)
- Genetic cluster of strains of Streptococcus thermophilus with unique rheological properties for dairy fermentation (2009) (1)
- Draft Genome Sequence of Lactobacillus sp. Strain TCF032-E4, Isolated from Fermented Radish (2015) (1)
- Host-encoded, cell surface-associated exopolysaccharide required for adsorption and infection by lactococcal P335 phage subtypes (2022) (1)
- The CRISPR/Cas bacterial immune system cleaves phage and plasmid DNA (2010) (1)
- Consistency imparting lactic acid bacteria (2004) (0)
- Author Correction: A mutation in the methionine aminopeptidase gene provides phage resistance in Streptococcus thermophilus (2020) (0)
- Using the CRISPR-associated genes (cas) (2006) (0)
- CRISPR sequences from bifidobacteria (2009) (0)
- What history tells us CRISPR-Cas: The discovery of an immune system in prokaryotes (2015) (0)
- Cloning of the mouse satellite DNA. (1981) (0)
- Lactic bacteria texturing. (2004) (0)
- An anti-CRISPR from a virulent streptococcal phage inhibits Streptococcus pyogenes Cas9 (2017) (0)
- Approach to transform ring of bacteria from genus streptococcus using natural powers (2010) (0)
- Rodolphe Barrangou , Viruses in Prokaryotes CRISPR Provides Acquired Resistance (2007) (0)
- Functions and Applications of RNA‐Guided CRISPR‐Cas Immune Systems (2014) (0)
- Bacteries lactiques texturantes (2004) (0)
- Labeled microorganisms and method for labeling (2007) (0)
- Characterization of: Wed-186streptococcus thermophilus: Wed-186csm complex mediated Crispr interference in vitro: Wed-186 (2014) (0)
- Expanding natural transformation to improve beneficial lactic acid bacteria (2022) (0)
- Microorganisms marked and methods for labeling. (2007) (0)
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