Pier Mannuccio Mannucci
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Computer Science
Pier Mannuccio Mannucci's Degrees
- PhD Computer Science University of Florence
- Masters Artificial Intelligence Consorzio ICoN
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(Suggest an Edit or Addition)Pier Mannuccio Mannucci's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study (2012) (2002)
- Genome-wide meta-analyses identify multiple loci associated with smoking behavior (2010) (1107)
- Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants (2009) (1100)
- Update on the pathophysiology and classification of von Willebrand disease: a report of the Subcommittee on von Willebrand Factor (2006) (1060)
- The hemophilias--from royal genes to gene therapy. (2001) (969)
- The coagulopathy of chronic liver disease. (2011) (925)
- Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease (2011) (894)
- Inherited Thrombophilia: Part 1 (1996) (637)
- Persistent Activation of Coagulation Mechanism in Unstable Angina and Myocardial Infarction (1994) (611)
- Expert position paper on air pollution and cardiovascular disease. (2015) (597)
- 1-DEAMINO-8-D-ARGININE VASOPRESSIN: A NEW PHARMACOLOGICAL APPROACH TO THE MANAGEMENT OF HAEMOPHILIA AND VON WILLEBRAND'S DISEASE (1977) (548)
- The risk of recurrent deep venous thrombosis among heterozygous carriers of both factor V Leiden and the G20210A prothrombin mutation. (1999) (508)
- Changes in health and disease of the metalloprotease that cleaves von Willebrand factor. (2001) (507)
- An imbalance of pro- vs anti-coagulation factors in plasma from patients with cirrhosis. (2009) (499)
- Impact, Diagnosis and Treatment of von Willebrand Disease (2000) (497)
- Desmopressin (DDAVP) in the treatment of bleeding disorders: the first 20 years. (1997) (484)
- Inherited thrombophilia: pathogenesis, clinical syndromes, and management. (1996) (474)
- Recessively inherited coagulation disorders. (2004) (459)
- Different risks of thrombosis in four coagulation defects associated with inherited thrombophilia: a study of 150 families. (1998) (412)
- Heightened interaction between platelets and factor VIII/von Willebrand factor in a new subtype of von Willebrand's disease. (1980) (395)
- Mechanism of Plasminogen Activator and Factor VIII Increase after Vasoactive Drugs (1975) (388)
- Oligospecificity of the cellular adhesion receptor Mac-1 encompasses an inducible recognition specificity for fibrinogen (1988) (382)
- Air pollution and cardiovascular disease. (2012) (377)
- A Randomized Trial of Factor VIII and Neutralizing Antibodies in Hemophilia A. (2016) (374)
- Cost of care and quality of life for patients with hemophilia complicated by inhibitors: the COCIS Study Group. (2003) (368)
- Thrombin generation in patients with cirrhosis: The role of platelets (2006) (361)
- Inherited Thrombophilia*: Part 2 (1996) (308)
- Health Effects of Ambient Air Pollution in Developing Countries (2017) (302)
- Desmopressin: a nontransfusional form of treatment for congenital and acquired bleeding disorders. (1988) (291)
- The Thrombogram in Rare Inherited Coagulation Disorders: Its Relation to Clinical Bleeding (2002) (285)
- Response of Factor VIII/von Willebrand Factor to DDAVP in Healthy Subjects and Patients with Haemophilia A and von Willebrand's Disease (1981) (284)
- Prevention and treatment of major blood loss. (2007) (282)
- ADAMTS13 autoantibodies in patients with thrombotic microangiopathies and other immunomediated diseases. (2005) (275)
- Polypharmacy, length of hospital stay, and in-hospital mortality among elderly patients in internal medicine wards. The REPOSI study (2011) (273)
- Role of the JAK2 mutation in the diagnosis of chronic myeloproliferative disorders in splanchnic vein thrombosis (2006) (269)
- Tissue-factor antigen and activity in human coronary atherosclerotic plaques (1997) (256)
- IMPROVEMENT IN THE HAEMOSTATIC DEFECT OF URAEMIA AFTER TREATMENT WITH RECOMBINANT HUMAN ERYTHROPOIETIN (1987) (255)
- N-Terminal Pro-Brain Natriuretic Peptide on Admission Has Prognostic Value Across the Whole Spectrum of Acute Coronary Syndromes (2004) (249)
- DEFICIENCIES OF PROTEIN C, AN INHIBITOR OF BLOOD COAGULATION (1982) (248)
- Multimeric composition of factor VIII/von Willebrand factor following administration of DDAVP: implications for pathophysiology and therapy of von Willebrand's disease subtypes (1982) (247)
- Hypercoagulability in centenarians: the paradox of successful aging. (1995) (243)
- The Coagulopathy of Chronic Liver Disease (2012) (240)
- ADAMTS13 and anti-ADAMTS13 antibodies as markers for recurrence of acquired thrombotic thrombocytopenic purpura during remission (2008) (240)
- Clinical and molecular predictors of thrombocytopenia and risk of bleeding in patients with von Willebrand disease type 2B: a cohort study of 67 patients. (2009) (240)
- Rare coagulation deficiencies (2002) (238)
- Treatment of von Willebrand's disease (1997) (237)
- Multiple diseases and polypharmacy in the elderly: challenges for the internist of the third millennium (2011) (232)
- Transmission of Hepatitis A to Patients with Hemophilia by Factor VIII Concentrates Treated with Organic Solvent and Detergent To Inactivate Viruses (1994) (232)
- Hyperhomocysteinemia in cerebral vein thrombosis. (2003) (229)
- Risk Factors and Recurrence Rate of Primary Deep Vein Thrombosis of the Upper Extremities (2004) (228)
- Large-Scale Gene-Centric Analysis Identifies Novel Variants for Coronary Artery Disease (2011) (228)
- Effects of exposure to air pollution on blood coagulation (2007) (226)
- No Evidence of Association Between Prothrombotic Gene Polymorphisms and the Development of Acute Myocardial Infarction at a Young Age (2003) (221)
- Biologic response to desmopressin in patients with severe type 1 and type 2 von Willebrand disease: results of a multicenter European study. (2004) (218)
- Risk factors for thrombophilia in extrahepatic portal vein obstruction (2005) (217)
- Epitope mapping of ADAMTS13 autoantibodies in acquired thrombotic thrombocytopenic purpura. (2004) (216)
- Exposure to particulate air pollution and risk of deep vein thrombosis. (2008) (211)
- Von Willebrand's disease in the year 2003: towards the complete identification of gene defects for correct diagnosis and treatment. (2003) (210)
- Past, present and future of hemophilia: a narrative review (2012) (206)
- Environmental risk factors for inhibitor development in children with haemophilia A: a case–control study (2005) (203)
- Conjugated estrogens for the management of bleeding associated with renal failure. (1986) (200)
- Rare Coagulation Disorders (1999) (197)
- Effects on health of air pollution: a narrative review (2015) (194)
- A common mutation in the methylenetetrahydrofolate reductase gene (C677T) increases the risk for deep-vein thrombosis in patients with mutant factor V (factor V:Q506). (1997) (193)
- von Willebrand factor cleaving protease (ADAMTS13) is deficient in recurrent and familial thrombotic thrombocytopenic purpura and hemolytic uremic syndrome. (2002) (192)
- Severe hemophilia with mild bleeding phenotype: molecular characterization and global coagulation profile (2010) (192)
- A shortened activated partial thromboplastin time is associated with the risk of venous thromboembolism. (2004) (189)
- Identification of a new congenital defect of platelet function characterized by severe impairment of platelet responses to adenosine diphosphate. (1992) (187)
- Clinical manifestations and complications of childbirth and replacement therapy in 385 Iranian patients with type 3 von Willebrand disease. (2000) (187)
- Modern treatment of haemophilia. (1995) (186)
- The incidence of venous thromboembolism in asymptomatic carriers of a deficiency of antithrombin, protein C, or protein S: a prospective cohort study. (1999) (183)
- How I treat age-related morbidities in elderly persons with hemophilia. (2009) (183)
- Prediction of Deep Vein Thrombosis after Elective Hip Replacement Surgery by Preoperative Clinical and Haemostatic Variables: The ECAT DVT Study (1999) (181)
- Thrombogenicity and cardiovascular effects of ambient air pollution. (2011) (179)
- Treatment of von Willebrand disease with a high-purity factor VIII/von Willebrand factor concentrate: a prospective, multicenter study. (2002) (179)
- High thrombin generation measured in the presence of thrombomodulin is associated with an increased risk of recurrent venous thromboembolism (2008) (178)
- Abnormalities of hemostasis in chronic liver disease: reappraisal of their clinical significance and need for clinical and laboratory research. (2007) (177)
- Mild to moderate reduction of a von Willebrand factor cleaving protease (ADAMTS-13) in pregnant women with HELLP microangiopathic syndrome. (2003) (177)
- Acquired dysfunction due to the circulation of "exhausted" platelets. (1980) (176)
- A factor V genetic component differing from factor V R506Q contributes to the activated protein C resistance phenotype. (1997) (173)
- Back to the future: a recent history of haemophilia treatment (2008) (171)
- Patterns of development of tachyphylaxis in patients with haemophilia and von Willebrand disease after repeated doses of desmopressin (DDAVP) (1992) (169)
- Treatment of acquired von Willebrand syndrome in patients with monoclonal gammopathy of uncertain significance: comparison of three different therapeutic approaches. (1998) (169)
- Studies on the prolonged bleeding time in von Willebrand's disease. (1976) (168)
- DDAVP enhances platelet adherence and platelet aggregate growth on human artery subendothelium. (1984) (167)
- How I treat patients with von Willebrand disease. (2001) (166)
- Risk of venous thromboembolism after air travel: interaction with thrombophilia and oral contraceptives. (2003) (165)
- Drug therapy: Prevention and treatment of major blood loss (2007) (162)
- Evidence that low protein C contributes to the procoagulant imbalance in cirrhosis. (2013) (161)
- Clinical Manifestations and Management of Inherited Thrombophilia: Retrospective Analysis and Follow-up after Diagnosis of 238 Patients with Congenital Deficiency of Antithrombin III, Protein C, Protein S (1994) (161)
- The coagulopathy of cirrhosis assessed by thromboelastometry and its correlation with conventional coagulation parameters. (2008) (159)
- Resistance to Activated Protein C in Nine Thrombophilic Families: Interference in a Protein S Functional Assay (1993) (158)
- Absence of hepatitis after treatment with a pasteurized factor VIII concentrate in patients with hemophilia and no previous transfusions. (1987) (157)
- Treatment of von Willebrand's Disease. (2004) (157)
- von Willebrand factor cleaving protease (ADAMTS‐13) and ADAMTS‐13 neutralizing autoantibodies in 100 patients with thrombotic thrombocytopenic purpura (2004) (153)
- Guidelines for the diagnosis and management of von Willebrand disease in Italy (2002) (152)
- Risk of venous thromboembolism and clinical manifestations in carriers of antithrombin, protein C, protein S deficiency, or activated protein C resistance: a multicenter collaborative family study. (1999) (150)
- Quality of life is associated to the orthopaedic status in haemophilic patients with inhibitors (2006) (150)
- Controlled trial of desmopressin in liver cirrhosis and other conditions associated with a prolonged bleeding time (1986) (149)
- Hemostatic drugs. (1998) (149)
- Studies of the pathophysiology of acquired von Willebrand's disease in seven patients with lymphoproliferative disorders or benign monoclonal gammopathies. (1984) (148)
- Changing Concepts of Cirrhotic Coagulopathy (2017) (148)
- Association of Anticholinergic Burden with Cognitive and Functional Status in a Cohort of Hospitalized Elderly: Comparison of the Anticholinergic Cognitive Burden Scale and Anticholinergic Risk Scale (2013) (147)
- Purinoceptors on blood platelets: further pharmacological and clinical evidence to suggest the presence of two ADP receptors (1995) (143)
- The low risk of hepatitis C virus transmission among sexual partners of hepatitis C-infected hemophilic males: an international, multicenter study. (1992) (143)
- Thrombotic risk factors: Basic pathophysiology (2010) (143)
- Binding of von Willebrand factor to glycoproteins Ib and IIb/IIIa complex: affinity is related to multimeric size (1989) (143)
- Immunoradiometric Assay of Factor VIII Related Antigen, with Observations in 32 Patients with von Willebrand's Disease (1976) (142)
- The risk of venous thromboembolism in family members with mutations in the genes of factor V or prothrombin or both. (2000) (140)
- Risk of Pregnancy-related Venous Thrombosis in Carriers of Severe Inherited Thrombophilia (2001) (140)
- High prevalence of antibody to hepatitis C virus in multitransfused hemophiliacs with normal transaminase levels. (1990) (140)
- Detection of the imbalance of procoagulant versus anticoagulant factors in cirrhosis by a simple laboratory method (2010) (140)
- Venous Thromboembolism in Von Willebrand Disease (2002) (138)
- Living Near Major Traffic Roads and Risk of Deep Vein Thrombosis (2009) (136)
- ADAMTS13 activity to antigen ratio in physiological and pathological conditions associated with an increased risk of thrombosis (2007) (136)
- Hypercoagulability in patients with type 2 diabetes mellitus detected by a thrombin generation assay (2011) (135)
- Laboratory investigation of thrombophilia. (2001) (132)
- Human parvovirus B19 infection in hemophiliacs first infused with two high‐purity, virally attenuated factor Vlll concentrates (1992) (132)
- Health status and quality of life of elderly persons with severe hemophilia born before the advent of modern replacement therapy (2009) (132)
- Comparison of four virus-inactivated plasma concentrates for treatment of severe von Willebrand disease: a cross-over randomized trial. (1992) (129)
- Hemostasis Testing during Massive Blood Replacement A Study of 172 Cases (1982) (129)
- Genetic diagnosis of haemophilia and other inherited bleeding disorders (2006) (129)
- Incidence of thrombotic complications in patients with haematological malignancies with central venous catheters: a prospective multicentre study (2005) (128)
- Hemophilia: treatment options in the twenty‐first century (2003) (128)
- Low Platelet 2β1 Levels in Type I von Willebrand Disease Correlate With Impaired Platelet Function in a High Shear Stress System (1999) (127)
- Short‐term effects of air pollution on cardiovascular diseases: outcomes and mechanisms (2007) (127)
- Report of the Working Party on Acquired Inhibitors of Coagulation: Studies of the “Lupus” Anticoagulant (1983) (126)
- Binding of fibrinogen to human monocytes. (1986) (123)
- Different bleeding risk in type 2A and 2M von Willebrand disease: a 2‐year prospective study in 107 patients (2012) (123)
- Incidence of bleeding symptoms in 100 patients with inherited afibrinogenemia or hypofibrinogenemia (2006) (122)
- Effects of secondary prophylaxis started in adolescent and adult haemophiliacs (2008) (122)
- Missense mutations in the human beta fibrinogen gene cause congenital afibrinogenemia by impairing fibrinogen secretion. (2000) (122)
- Hemophilia A in the third millennium. (2013) (121)
- Association between clusters of diseases and polypharmacy in hospitalized elderly patients: results from the REPOSI study. (2011) (119)
- Acquired coagulation disorders: revisited using global coagulation/anticoagulation testing (2009) (119)
- Decrease in protein C antigen and formation of an abnormal protein soon after starting oral anticoagulant therapy (1984) (119)
- Comparison of the rates of joint arthroplasty in patients with severe factor VIII and IX deficiency: an index of different clinical severity of the 2 coagulation disorders. (2009) (117)
- Plasma levels of von Willebrand factor regulate ADAMTS‐13, its major cleaving protease (2004) (117)
- Von Willebrand factor cleaving protease (ADAMTS-13) in 123 patients with connective tissue diseases (systemic lupus erythematosus and systemic sclerosis). (2003) (117)
- A 6-month versus a 12-month surveillance for hepatocellular carcinoma in 559 hemophiliacs infected with the hepatitis C virus. (2003) (117)
- CYP2C9 genotypes and dose requirements during the induction phase of oral anticoagulant therapy (2004) (117)
- Thrombosis during Pregnancy and Surgery in Patients with Congenital Deficiency of Antithrombin III, Protein C, Protein S (1994) (116)
- The bleeding score predicts clinical outcomes and replacement therapy in adults with von Willebrand disease. (2014) (116)
- Molecular defects in type 3 von Willebrand disease: updated results from 40 multiethnic patients. (2003) (116)
- The transfusion-associated transmission of parvovirus B19. (1999) (116)
- Introduction. Rare bleeding disorders: general aspects of clinical features, diagnosis, and management. (2009) (115)
- High Prevalence of Hyperhomocysteinemia in Patients with Inflammatory Bowel Disease: a Pathogenic Link with Thromboembolic Complications? (1998) (115)
- Multimorbidity and polypharmacy in the elderly: lessons from REPOSI (2014) (115)
- Inherited risk factors for venous thromboembolism (2014) (115)
- Pharmacokinetics and safety of a novel recombinant human von Willebrand factor manufactured with a plasma-free method: a prospective clinical trial. (2013) (114)
- Global hemostasis tests in patients with cirrhosis before and after prophylactic platelet transfusion (2013) (114)
- ABO blood group and thrombotic vascular disease (2014) (112)
- The varied sensitivity of partial thromboplastin and prothrombin time reagents in the demonstration of the lupus-like anticoagulant. (2009) (112)
- Heparin in pregnant women with previous placenta-mediated pregnancy complications: a prospective, randomized, multicenter, controlled clinical trial. (2012) (112)
- Are Capillary Whole Blood Coagulation Monitors Suitable for the Control of Oral Anticoagulant Treatment by the International Normalized Ratio? (1993) (111)
- A Prospective Multicenter Study of Hepatocellular Carcinoma in Italian Hemophiliacs With Chronic Hepatitis C (1998) (111)
- Time to face the challenge of multimorbidity. A European perspective from the joint action on chronic diseases and promoting healthy ageing across the life cycle (JA-CHRODIS). (2015) (110)
- von Willebrand factor/factor VIII concentrate (Haemate® P) dosing based on pharmacokinetics: a prospective multicenter trial in elective surgery (2007) (109)
- Treatment of von Willebrand Disease. (1998) (108)
- Report of a joint WHO/WFH meeting on the control of haemophilia: carrier detection and prenatal diagnosis. (1993) (108)
- Molecular basis of von Willebrand disease type IIB. Candidate mutations cluster in one disulfide loop between proposed platelet glycoprotein Ib binding sequences. (1991) (107)
- Co‐morbidities and quality of life in elderly persons with haemophilia (2010) (106)
- Spectrum of von Willebrand's Disease: a Study of 100 Cases (1977) (106)
- Factor VIII gene (F8) mutations as predictors of outcome in immune tolerance induction of hemophilia A patients with high‐responding inhibitors (2009) (104)
- Transmission of parvovirus B19 by coagulation factor concentrates exposed to 100°C heat after lyophilization (1997) (103)
- Free Protein S Deficiency Is a Risk Factor for Venous Thrombosis (1997) (103)
- DESMOPRESSIN AND THROMBOSIS (1989) (103)
- Gene polymorphisms predicting high plasma levels of coagulation and fibrinolysis proteins. A study in centenarians. (1997) (102)
- Acquired haemophilia A: A 2013 update (2013) (101)
- Outbreak of hepatitis A among Italian patients with haemophilia (1992) (101)
- Prophylaxis in severe forms of von Willebrand's disease: results from the von Willebrand Disease Prophylaxis Network (VWD PN) (2013) (101)
- The Italian AICE-Genetics hemophilia A database: results and correlation with clinical phenotype (2008) (101)
- Pregnancy in women with different types of von Willebrand disease. (1986) (101)
- Biochemical and Metabolic Aspects of Platelet Dysfunction in Chronic Myeloproliferative Disorders (1982) (100)
- Laboratory control of oral anticoagulant treatment by the INR system in patients with the antiphospholipid syndrome and lupus anticoagulant. Results of a collaborative study involving nine commercial thromboplastins (2001) (100)
- Treatment of severe von Willebrand disease with a high‐purity von Willebrand factor concentrate (Wilfactin®): a prospective study of 50 patients (2007) (100)
- Impact on human health of climate changes. (2015) (99)
- Markers of Procoagulant Imbalance in Patients with Inherited Thrombophilic Syndromes (1992) (98)
- Factor VIII products and inhibitor development: the SIPPET study (survey of inhibitors in plasma‐product exposed toddlers) (2007) (97)
- Released adenosine diphosphate stabilizes thrombin-induced human platelet aggregates. (1990) (97)
- Circulating microparticles and risk of venous thromboembolism. (2009) (97)
- Pharmacokinetics and safety of fibrinogen concentrate (2009) (97)
- Pattern of symptoms in 93 Iranian patients with severe factor XIII deficiency (2003) (97)
- Platelets: an update on diagnosis and management of thrombocytopenic disorders. (2001) (96)
- Hemophilia therapy: the future has begun (2020) (96)
- A sensitive ristocetin co-factor activity assay with recombinant glycoprotein Ibalpha for the diagnosis of patients with low von Willebrand factor levels. (2004) (95)
- An investigation of three patients with Christmas disease due to an abnormal type of factor ix (1968) (95)
- The first ambulatory screening on thromboembolism: a multicentre, cross‐sectional, observational study on risk factors for venous thromboembolism (2005) (94)
- The Effect of Desmopressin on Reducing Blood Loss in Cardiac Surgery – A Meta-Analysis of Double-Blind, Placebo-Controlled Trials (1995) (94)
- Inhibitors of propagation of coagulation (factors VIII, IX and XI): a review of current therapeutic practice. (2011) (94)
- Thrombin generation in plasma from patients with cirrhosis supplemented with normal plasma: considerations on the efficacy of treatment with fresh-frozen plasma (2012) (94)
- Fibrinolytic shut‐down after surgery: impairment of the balance between tissue‐type plasminogen activator and its specific inhibitor (1985) (93)
- CORRECTION OF ABNORMAL COAGULATION IN CHRONIC LIVER DISEASE BY COMBINED USE OF FRESH-FROZEN PLASMA AND PROTHROMBIN COMPLEX CONCENTRATES (1976) (93)
- Clinical manifestations in 28 Italian and Iranian patients with severe factor VII deficiency (1997) (93)
- Classic thrombophilic gene variants (2015) (93)
- Activation of the coagulation cascade after infusion of a factor XI concentrate in congenitally deficient patients. (1994) (92)
- Oral surgery in patients on oral anticoagulant therapy: a randomized comparison of different intensity targets. (2007) (92)
- Prospective Multicenter Study on Subcutaneous Concentrated Desmopressin for Home Treatment of Patients with von Willebrand Disease and Mild or Moderate Hemophilia A (1996) (92)
- Measurement of von Willebrand factor cleaving protease (ADAMTS‐13): results of an international collaborative study involving 11 methods testing the same set of coded plasmas (2004) (92)
- A factor V genetic component differing from factor V R506Q contributes to the activated protein C resistance phenotype (1997) (92)
- Abnormal hemostasis tests and bleeding in chronic liver disease: are they related? No (2006) (90)
- Low Prevalence of Factor V:Q506 in 41 Patients with Isolated Pulmonary Embolism (1997) (89)
- Low Prevalence of the Factor V Leiden Mutation Among “Severe” Hemophiliacs with a “Milder” Bleeding Diathesis (1995) (89)
- Thrombotic adverse events to coagulation factor concentrates for treatment of patients with haemophilia and von Willebrand disease: a systematic review of prospective studies (2012) (89)
- Hemophilia and related bleeding disorders: a story of dismay and success. (2002) (89)
- The risk of recurrent venous thromboembolism among heterozygous carriers of the G20210A prothrombin gene mutation (2001) (88)
- Factors influencing the long‐term outcome of primary total knee replacement in haemophiliacs: a review of 116 procedures at a single institution (2009) (88)
- Markers of activation of coagulation and fibrinolysis in patients with Cushing’s syndrome (2000) (88)
- Randomized controlled trial of desmopressin plus terlipressin vs. terlipressin alone for the treatment of acute variceal hemorrhage in cirrhotic patients: A multicenter, double‐blind study (1993) (87)
- Clinical evaluation of moroctocog alfa (AF‐CC), a new generation of B‐domain deleted recombinant factor VIII (BDDrFVIII) for treatment of haemophilia A: demonstration of safety, efficacy, and pharmacokinetic equivalence to full‐length recombinant factor VIII (2009) (86)
- Seasonal and monthly variability in the incidence of venous thromboembolism (2011) (86)
- Intravenous and Subcutaneous Administration of Desmopresssin (DDAVP) to Hemophiliacs: Pharmacokinetics and Factor VIII Responses (1987) (86)
- Embryo implantation after assisted reproductive procedures and maternal thrombophilia. (2003) (86)
- Laboratory Screening of Inherited Thrombotic Syndromes (1987) (85)
- Safety Profile of Porcine Factor VIII and Its Use as Hospital and Home-Therapy for Patients with Haemophilia-A and Inhibitors: the Results of An International Survey (1996) (85)
- Shear-induced platelet aggregation is potentiated by desmopressin and inhibited by ticlopidine. (1993) (85)
- Risk Factors for Deep Venous Thrombosis of the Upper Extremities (1997) (85)
- A randomized, double-blind comparison of two dosage levels of recombinant factor VIIa in the treatment of joint, muscle and mucocutaneous haemorrhages in persons with haemophilia A and B, with and without inhibitors. rFVIIa Study Group. (1998) (84)
- Air Pollution, Smoking, and Plasma Homocysteine (2006) (84)
- Clinical Evaluation of Viral Safety of Coagulation Factor VIII and IX Concentrates (1993) (83)
- Effect of tamoxifen on measurements of hemostasis in healthy women. (1996) (83)
- Molecular Characterisation and Three-Dimensional Structural Analysis of Mutations in 21 Unrelated Families with Inherited Factor VII Deficiency (2000) (83)
- Immune tolerance induction with a high purity von Willebrand factor/VIII complex concentrate in haemophilia A patients with inhibitors at high risk of a poor response (2007) (83)
- Evidence-based recommendations on the treatment of von Willebrand disease in Italy. (2009) (83)
- Safety of intravenous tranexamic acid in patients undergoing majororthopaedic surgery: a meta-analysis of randomised controlled trials. (2018) (83)
- Controlled trial of desmopressin in liver cirrhosis and other conditions associated with a prolonged bleeding time. (1986) (83)
- Venous and arterial thrombosis: different sides of the same coin? (2008) (82)
- Alterations of Factor VIII von Willebrand Factor in Clinical Conditions Associated with an Increase in its Plasma Concentration (1981) (82)
- VIRUCIDAL TREATMENT OF CLOTTING FACTOR CONCENTRATES (1988) (82)
- Procoagulant imbalance in patients with non-alcoholic fatty liver disease. (2014) (82)
- High levels of factor VIII and risk of extra-hepatic portal vein obstruction. (2009) (81)
- Italian Registry of Haemophilia and Allied Disorders. Objectives, methodology and data analysis (2008) (81)
- DDAVP shortens the prolonged bleeding times of patients with severe von Willebrand disease treated with cryoprecipitate. Evidence for a mechanism of action independent of released von Willebrand factor (1989) (81)
- Haemophilia: strategies for carrier detection and prenatal diagnosis. (1993) (81)
- Thrombin generation is not increased in the blood of hemophilia B patients after the infusion of a purified factor IX concentrate. (1990) (81)
- Anti‐beta 2 glycoprotein I antibodies and the risk of myocardial infarction in young premenopausal women (2007) (80)
- Congenital afibrinogenemia: mutations leading to premature termination codons in fibrinogen A alpha-chain gene are not associated with the decay of the mutant mRNAs. (2001) (80)
- Alloantibodies in von Willebrand disease. (2013) (80)
- Risk factors for hospital readmission of elderly patients. (2013) (79)
- Safety and immunogenicity of HIV-1 Tat toxoid in immunocompromised HIV-1-infected patients. (1998) (79)
- Deficiency of (33P)2MeS-ADP Binding Sites on Platelets with Secretion Defect, Normal Granule Stores and Normal Thromboxane A2 Production (1997) (78)
- Atherosclerosis and von Willebrand factor (1984) (78)
- Human recombinant DNA‐derived antihemophilic factor in the treatment of previously untreated patients with hemophilia A: final report on a hallmark clinical investigation (2004) (78)
- Initial experience from a double‐blind, placebo‐controlled, clinical outcome study of ARC1779 in patients with thrombotic thrombocytopenic purpura (2012) (78)
- Naturally occurring anticoagulants and bone marrow transplantation: plasma protein C predicts the development of venocclusive disease of the liver (1993) (77)
- Ticlopidine Selectively Inhibits Human Platelet Responses to Adenosine Diphosphate (1991) (77)
- Pharmacokinetic studies on Wilfactin®, a von Willebrand factor concentrate with a low factor VIII content treated with three virus‐inactivation/removal methods (2005) (77)
- Replacement Therapy with Virus—Inactivated Plasma Concentrates in von Willebrand Disease (1992) (77)
- Italian guidelines for the diagnosis and treatment of patients with haemophilia and inhibitors (2005) (77)
- Clinical indications for desmopressin (DDAVP) in congenital and acquired von Willebrand disease. (1991) (76)
- Von Willebrand Disease Type 2M “Vicenza” in Italian and German Patients: Identification of the First Candidate Mutation (G3864A; R1205H) in 8 Families (2000) (76)
- Particulate air pollution and cardiovascular risk: short-term and long-term effects. (2009) (75)
- Antibodies to tissue-type plasminogen activator (tPA) in patients with antiphospholipid syndrome: evidence of interaction between the antibodies and the catalytic domain of tPA in 2 patients. (2004) (75)
- Clinical use of Haemate P in inherited von Willebrand's disease: a cohort study on 100 Italian patients. (2007) (75)
- Controlled trial of streptokinase and heparin in acute myocardial infarction. (1971) (75)
- Attitudes towards polypharmacy and medication withdrawal among older inpatients in Italy (2016) (74)
- Use of Porcine Factor VIII in the Management of Seventeen Patients with Factor VIII Antibodies (1984) (74)
- Delta infection and liver disease in hemophilic carriers of hepatitis B surface antigen. (1982) (74)
- Rotational thromboelastography for monitoring of fibrinogen concentrate therapy in fibrinogen deficiency (2008) (74)
- Factor VIII-related properties in platelets from patients with von Willebrand's disease. (1978) (74)
- Screening for the FV: Q506 Mutation – Evaluation of Thirteen Plasma-based Methods for their Diagnostic Efficacy in Comparison with DNA Analysis (1997) (73)
- How we choose factor VIII to treat hemophilia. (2012) (73)
- Hepatocellular carcinoma in hemophilia (1991) (73)
- Low Plasma Levels of Vitamin B6 Are Independently Associated With a Heightened Risk of Deep-Vein Thrombosis (2001) (73)
- EUHASS: The European Haemophilia Safety Surveillance system. (2011) (73)
- Hypercoagulability in splenectomized thalassemic patients detected by whole-blood thromboelastometry, but not by thrombin generation in platelet-poor plasma (2009) (73)
- The endogenous thrombin potential and the risk of venous thromboembolism. (2007) (72)
- Coinheritance of the HR2 haplotype in the factor V gene confers an increased risk of venous thromboembolism to carriers of factor V R506Q (factor V Leiden). (1999) (72)
- Molecular Characterization of a Multiethnic Group of 21 Patients with Type 3 von Willebrand Disease (2000) (72)
- Additional genetic risk factors for venous thromboembolismin carriers of the factor V Leiden mutation (1998) (71)
- Interaction of porcine von Willebrand factor with the platelet glycoproteins Ib and IIb/IIIa complex (1992) (71)
- Precipitating antibodies to factor VIII/von Willebrand factor in von Willebrand's disease: effects on replacement therapy. (1981) (71)
- Gene mutations and three‐dimensional structural analysis in 13 families with severe factor X deficiency (2002) (71)
- Coinheritance of the HR2 Haplotype in the Factor V Gene Confers an Increased Risk of Venous Thromboembolism to Carriers of Factor V R506Q (Factor V Leiden) (1999) (71)
- The management of hemophilia in elderly patients (2007) (70)
- Is haemophilia B less severe than haemophilia A? (2013) (70)
- Laboratory Diagnosis of Lupus Anticoagulants for Patients on Oral Anticoagulant Treatment (2002) (69)
- Life‐threatening reaction to factor VIII concentrate in a patient with severe von Willebrand disease and alloantibodies to von Willebrand factor (1987) (69)
- Normal thrombin generation in neonates in spite of prolonged conventional coagulation tests (2008) (69)
- Mutant factor V (Arg506Gln) in healthy centenarians (1996) (69)
- Pharmacokinetics of Monoclonally-Purified and Recombinant Factor VIII in Patients with Severe von Willebrand Disease (1993) (68)
- The Factor‐X Defect: Recognition of Abnormal Forms of Factor X (1970) (68)
- Identification and Three-dimensional Structural Analysis of Nine Novel Mutations in Patients with Prothrombin Deficiency (2000) (68)
- Randomized controlled trial of desmopressin plus terlipressin vs. terlipressin alone for the treatment of acute variceal hemorrhage in cirrhotic patients: a multicenter, double-blind study. New Italian Endoscopic Club. (1993) (68)
- Abnormalities of hemostasis and bleeding in chronic liver disease: the paradigm is challenged (2010) (68)
- Von Willebrand disease‐associated angiodysplasia: a few answers, still many questions (2013) (67)
- The Post-thrombotic Syndrome in Young Women: Retrospective Evaluation of Prognostic Factors (1998) (67)
- Venous thromboembolism in acute stroke. Prognostic importance of hypercoagulability. (1992) (67)
- High Frequency of the C677T Mutation in the Methylenetetrahydrofolate Reductase (MTHFR) Gene in Northern Italy (1997) (66)
- Hemostasis Abnormalities in Patients with Vascular Dementia and Alzheimer’s Disease (1996) (66)
- Low borderline plasma levels of antithrombin, protein C and protein S are risk factors for venous thromboembolism (2012) (66)
- Factor IXa-factor VIIIa-cell surface complex does not contribute to the basal activation of the coagulation mechanism in vivo. (1992) (66)
- CONGENITAL DEFICIENCY OF THROMBOXANE AND PROSTACYCLIN (1980) (66)
- Hypercoagulability in acute stroke (1987) (66)
- Thrombogenic potential of human coronary atherosclerotic plaques. (2001) (65)
- A 23bp Insertion in the Endothelial Protein C Receptor (EPCR) Gene Impairs EPCR Function (2001) (65)
- Adherence to antithrombotic therapy guidelines improves mortality among elderly patients with atrial fibrillation: insights from the REPOSI study (2016) (65)
- Liver dysfunction rather than intravascular coagulation as the main cause of low protein C and antithrombin III in acute leukemia (1984) (65)
- Molecular basis of fibrinogen Naples associated with defective thrombin binding and thrombophilia. Homozygous substitution of B beta 68 Ala----Thr. (1992) (65)
- TTP and ADAMTS13: When Is Testing Appropriate? (2007) (64)
- Subcutaneous desmopressin (DDAVP) shortens the bleeding time in uremia (1989) (64)
- Identification of differentially expressed genes in coronary atherosclerotic plaques from patients with stable or unstable angina by cDNA array analysis (2003) (64)
- Use of desmopressin (DDAVP) during early pregnancy in factor VIII-deficient women. (2005) (64)
- Deep intronic variations may cause mild hemophilia A (2011) (63)
- Rare bleeding disorders (2006) (63)
- Patients With Type 3 Severe von Willebrand Disease Are Not Protected Against Atherosclerosis: Results From a Multicenter Study in 47 Patients (2004) (63)
- Association between venous and arterial thrombosis: clinical implications. (2012) (63)
- Factor VIII antigen in the vessel walls in von Willebrand's disease and haemophilia A. (2009) (63)
- The JAK2 V617F mutation in patients with cerebral venous thrombosis (2012) (63)
- Low Levels of Heparin-releasable Tissue Factor Pathway Inhibitor in Young Patients with Thrombosis (1999) (63)
- Treatment of congenital antithrombin III deficiency with concentrates (1982) (62)
- Novel evidence for a greater burden of ambient air pollution on cardiovascular disease (2019) (62)
- Inhibitor development in previously treated hemophilia A patients: a systematic review, meta‐analysis, and meta‐regression (2013) (62)
- Atypical hemolytic uremic syndrome (aHUS): essential aspects of an accurate diagnosis. (2016) (61)
- Low platelet alpha2beta1 levels in type I von Willebrand disease correlate with impaired platelet function in a high shear stress system. (1999) (61)
- Gastrointestinal angiodysplasia and bleeding in von Willebrand disease (2014) (61)
- Drug–drug interactions in a cohort of hospitalized elderly patients (2013) (61)
- Plasminogen activator response after DDAVP: a clinico-pharmacological study. (1980) (60)
- Risk factors for postpartum hemorrhage in a cohort of 6011 Italian women. (2012) (60)
- Coagulation activation and long-term outcome in acute coronary syndromes. (2003) (60)
- Silica clotting time (SCT) as a screening and confirmatory test for detection of the lupus anticoagulants. (1992) (60)
- No activation of the common pathway of the coagulation cascade after a highly purified factor IX concentrate (1991) (59)
- How I treat rare venous thromboses. (2008) (59)
- Factor VIII replacement is still the standard of care in haemophilia A. (2019) (59)
- A Multicenter Controlled, Randomized, Open Trial of Interferon α2b Treatment of Anti–Human Immunodeficiency Virus-Negative Hemophilic Patients With Chronic Hepatitis C (1997) (59)
- Factor V Leiden and G20210A prothrombin mutation and the risk of subclavian vein thrombosis in patients with breast cancer and a central venous catheter. (2004) (58)
- Oral contraceptive use, thrombophilia and their interaction in young women with ischemic stroke. (2006) (58)
- Acquired storage pool disease in platelets during disseminated intravascular coagulation. (1976) (58)
- Short-term Exposure to High Altitude Causes Coagulation Activation and Inhibits Fibrinolysis (2002) (58)
- Defining Aging Phenotypes and Related Outcomes: Clues to Recognize Frailty in Hospitalized Older Patients (2016) (58)
- Degradation of von Willebrand factor in patients with acquired clinical conditions in which there is heightened proteolysis. (1993) (58)
- Hemostatic balance in patients with liver cirrhosis: Report of a consensus conference. (2016) (58)
- Molecular and phenotypic determinants of the response to desmopressin in adult patients with mild hemophilia A (2009) (58)
- Exercise training in mild hypertension: effects on blood pressure, left ventricular mass and coagulation factor VII and fibrinogen. (1997) (58)
- Type and location of venous thromboembolism in patients with factor V Leiden or prothrombin G20210A and in those with no thrombophilia (2007) (58)
- Patients with localized and disseminated tumors have reduced but measurable levels of ADAMTS-13 (von Willebrand factor cleaving protease). (2003) (58)
- Second international collaborative study evaluating performance characteristics of methods measuring the von Willebrand factor cleaving protease (ADAMTS‐13) (2008) (58)
- Correction of the bleeding time in treated patients with severe von willebrand disease is not solely dependent on the normal multimeric structure of plasma von willebrand factor (1987) (58)
- Old and new anticoagulant drugs: A minireview (2011) (58)
- A prothrombin time-based functional assay of protein S. (1990) (58)
- Thrombo-Inflammation in Cardiovascular Disease: An Expert Consensus Document from the Third Maastricht Consensus Conference on Thrombosis (2020) (58)
- Liver dysfunction rather than intravascular coagulation as the main cause of low protein C and antithrombin III in acute leukemia. (1984) (58)
- Protein C Antigen Is Not an Acute Phase Reactant and Is often High in Ischemic Heart Disease and Diabetes (1984) (58)
- Heightened Thrombin Generation in Individuals with Resistance to Activated Protein C (1996) (58)
- A new era for anticoagulants. (2009) (57)
- Thrombin and Cancer: From Molecular Basis to Therapeutic Implications (2012) (57)
- Intracranial haemorrhage in the Italian population of haemophilia patients with and without inhibitors (2012) (57)
- A multicenter pharmacokinetic study of the B‐domain deleted recombinant factor VIII concentrate using different assays and standards (2003) (57)
- The thrombospondin-1 N700S polymorphism is associated with early myocardial infarction without altering von Willebrand factor multimer size. (2006) (57)
- von Willebrand factor cleaving protease ( ADAMTS 13 ) is deficient in recurrent and familial thrombotic thrombocytopenic purpura and hemolytic uremic syndrome (2002) (56)
- Factor VIII: C increases after desmopressin in a subgroup of patients with autosomal recessive severe von Willebrand disease (1995) (56)
- Low risk for hepatitis C in hemophiliacs given a high-purity, pasteurized factor VIII concentrate. International Study Group. (1990) (56)
- Low risk of viral infection after administration of vapor‐heated factor VIII concentrate (1992) (56)
- Analysis of the tissue factor pathway inhibitor gene and antigen levels in relation to venous thrombosis (2001) (56)
- Identification of nine novel mutations in type I antithrombin deficiency by heteroduplex screening (1993) (55)
- Molecular analysis of the genotype-phenotype relationship in factor X deficiency (2000) (55)
- Platelets and the vessel wall: how much aspirin? (1980) (55)
- The association of factor V Leiden with myocardial infarction is replicated in 1880 patients with premature disease (2010) (55)
- Fibrinogen assays: a collaborative study of six different methods. C.I.S.M.E.L. Comitato Italiano per la Standardizzazione dei Metodi in Ematologia e Laboratorio. (1991) (54)
- Incidence of severe von Willebrand's disease. (1982) (54)
- Reduction in transmission of hepatitis C after the introduction of a heat‐treatment step in the production of C1‐inhibitor concentrate (1995) (54)
- Phenotype‐genotype characterization of 10 families with severe a subunit factor XIII deficiency (2004) (54)
- Factor V (Arg506⟶ Gln) Mutation in Young Survivors of Myocardial Infarction (1996) (53)
- International Collaborative Study for the Calibration of a Proposed Reference Preparation for Thromboplastin, Human Recombinant, Plain (1998) (53)
- Factor XI deficiency in Iranians: its clinical manifestations in comparison with those of classic hemophilia. (2002) (53)
- Source and purity of factor VIII products as risk factors for inhibitor development in patients with hemophilia A (2012) (53)
- Inhibitors to Factor VIII in a Family with Mild Hemophilia: Molecular Characterization and Response to Factor VIII and Desmopressin (1995) (53)
- Inhibitor eradication with rituximab in haemophilia: where do we stand? (2014) (52)
- Multicenter Study of Homocysteine Measurement – Performance Characteristics of Different Methods, Influence of Standards on Interlaboratory Agreement of Results (2001) (52)
- Effects of PCSK9 genetic variants on plasma LDL cholesterol levels and risk of premature myocardial infarction in the Italian population (2010) (52)
- Near‐patient testing devices to monitor oral anticoagulant therapy (2001) (52)
- Hemostatic defects in liver and renal dysfunction. (2012) (52)
- Protein C in acute stroke. (1988) (52)
- Role of Chloride Ions in Modulation of the Interaction between von Willebrand Factor and ADAMTS-13* (2005) (52)
- Formation of methionine sulfoxide by peroxynitrite at position 1606 of von Willebrand factor inhibits its cleavage by ADAMTS-13: A new prothrombotic mechanism in diseases associated with oxidative stress. (2010) (51)
- Different clinical severity of first episodes and recurrences of thrombotic thrombocytopenic purpura (2010) (51)
- Low-Dose Heparin and Deep-Vein Thrombosis after Total Hip Replacement (1976) (51)
- Protein S Deficiency Associated with “Juvenile” Arterial and Venous Thromboses (1986) (51)
- Familial Dysfunction of Protein S (1989) (51)
- Opposite changes of ADAMTS‐13 and von Willebrand factor after cardiac surgery (2005) (51)
- Risk of thromboembolic complications in patients with inflammatory bowel disease (1992) (51)
- Asymptomatic homozygous protein C deficiency. (1990) (50)
- Desmopressin, Surgery and Thrombosis (1994) (50)
- Genetic control of anticoagulation (1999) (50)
- Subcutaneous Desmopressin (DDAVP) Shortens the Prolonged Bleeding Time in Patients with Liver Cirrhosis (1990) (50)
- Low protein C in the neonatal period (1986) (50)
- Ndufc2 Gene Inhibition Is Associated With Mitochondrial Dysfunction and Increased Stroke Susceptibility in an Animal Model of Complex Human Disease (2016) (49)
- Precipitating antibodies in von Willebrand's disease (1976) (49)
- Management of inherited von Willebrand disease in Italy: results from the retrospective study on 1234 patients. (2011) (49)
- The role of thrombophilia in splanchnic vein thrombosis. (2008) (49)
- Immune tolerance induction with recombinant factor VIII in hemophilia A patients with high responding inhibitors. (2006) (49)
- Effects on bleeding complications of pharmacogenetic testing for initial dosing of vitamin K antagonists: a systematic review and meta‐analysis (2014) (49)
- Factor VII Clotting Assay: Influence of Different Thromboplastins and Factor VII-Deficient Plasmas (1991) (48)
- New anticoagulants for treatment of venous thromboembolism. (2012) (48)
- Long-Term Relationship Between Atrial Fibrillation, Multimorbidity and Oral Anticoagulant Drug Use. (2019) (48)
- Changes in clinical outcomes for community‐dwelling older people exposed to incident chronic polypharmacy: a comparison between 2001 and 2009 (2016) (47)
- Heightened thrombin formation but normal plasma levels of activated factor VII in patients with acute coronary syndromes. (1995) (47)
- ReFacto® 1 and Advate® 2 : a single‐dose, randomized, two‐period crossover pharmacokinetics study in subjects with haemophilia A (2007) (47)
- Suboptimal response to hepatitis B vaccine in drug users. (1991) (47)
- Desmopressin (DDAVP) for treatment of disorders of hemostasis. (1986) (47)
- Efficacy and inhibitor development in previously treated patients with haemophilia A switched to a B domain‐deleted recombinant factor VIII (2004) (47)
- Germinal Matrix Hemorrhage: Intraventricular Hemorrhage in Very-Low-Birth-Weight Infants The Independent Role of Inherited Thrombophilia (2011) (47)
- Tamoxifen reduces plasma homocysteine levels in healthy women. (1998) (47)
- Pharmacokinetic Properties of Recombinant Factor VIII Compared with a Monoclonally Purified Concentrate (Hemofil® M) (1992) (47)
- Congenital plasminogen deficiency associated with venous thromboembolism: therapeutic trial with stanozolol (1986) (46)
- The relationship between plasma homocysteine levels and bone mineral density in post-menopausal women. (2010) (46)
- Different Quantitative Apoptotic Traits in Coronary Atherosclerotic Plaques From Patients With Stable Angina Pectoris and Acute Coronary Syndromes (2004) (46)
- Polypharmacy in older people: lessons from 10 years of experience with the REPOSI register (2018) (46)
- Genetic hypercoagulability: prevention suggests testing family members. (2001) (46)
- Carrier detection in hemophilia A: a cooperative international study. I. The carrier phenotype. (1986) (46)
- Acquired von Willebrand syndrome: focused for hematologists (2020) (45)
- Treatment of Congenital Factor VII Deficiency with a New Concentrate (1978) (45)
- Diagnosis and management of von Willebrand disease (1999) (45)
- Effects of CYP2C9 and VKORC1 on INR variations and dose requirements during initial phase of anticoagulant therapy. (2008) (45)
- Determination of the International Sensitivity Index of a New Near-Patient Testing Device to Monitor Oral Anticoagulant Therapy (1997) (45)
- Low levels of protein Z and the risk of venous thromboembolism (2005) (45)
- Standard Nomenclature for Factor VIII and von Willebrand Factor: A Recommendation by the International Committee on Thrombosis and Haemostasis (1985) (45)
- Value of Normotest and antithrombin 3 in the assessment of liver function. (1973) (44)
- Characterization of two cases of acquired transitory von willebrand syndrome with ciprofloxacin: Evidence for heightened proteolysis of von willebrand factor (1995) (44)
- Revision of the Protocol Recommended for Studies of Safety from Hepatitis of Clotting Factor Concentrates (1989) (44)
- Platelet aggregation at high shear is impaired in patients with congenital defects of platelet secretion and is corrected by DDAVP: correlation with the bleeding time. (1995) (44)
- von Willebrand factor synthesized by endothelial cells from a patient with type IIB von Willebrand disease supports platelet adhesion normally but has an increased affinity for platelets. (1989) (43)
- Hemodialysis without anticoagulants: efficiency and hemostatic aspects. (1984) (43)
- Venous thrombosis and anticoagulant therapy (2001) (43)
- Another Protein S Functional Assay Is Sensitive to Resistance to Activated Protein C (1994) (43)
- Assessment of the Influence of Citrate Concentration on the International Normalized Ratio (INR) Determined with Twelve Reagent-instrument Combinations (1998) (43)
- Modern Treatment of Hemophilia: From the Shadows Towards the Light (1993) (43)
- Determination of total homocysteine in plasma: comparison of the Abbott IMx immunoassay with high performance liquid chromatography. (2002) (43)
- Absence of clinical, virological, and immunological signs of progression in HIV-1-infected patients receiving active anti-interferon-alpha immunization: a 30-month follow-up report. (1996) (43)
- The role of platelet von Willebrand factor in platelet adhesion and thrombus formation: a study of 34 patients with various subtypes of type I von Willebrand disease (1994) (43)
- Non-factor replacement therapy for haemophilia: a current update. (2018) (43)
- Coagulation activation and long-term outcome in acute coronary syndromes Running title: Coagulation activation and long-term outcome in CHD Section heading: Clinical observation (2003) (42)
- A prospective multicenter study of hepatocellular carcinoma in italian hemophiliacs with chronic hepatitis C. The Study Group of the Association of Italian Hemophilia Centers. (1998) (42)
- The natural history of occult or angiodysplastic gastrointestinal bleeding in von Willebrand disease (2015) (42)
- Absence of hyperhomocysteinemia in ten patients with primary pulmonary hypertension. (1997) (42)
- Markers of activated coagulation and their usefulness in the clinical laboratory. (1996) (42)
- Familial incidence of precipitating antibodies in von Willebrand's disease: a study of four cases. (1979) (42)
- COVID-19 Vaccine and Death: Causality Algorithm According to the WHO Eligibility Diagnosis (2021) (42)
- Cardiovascular disease in haemophilia patients: a contemporary issue (2010) (42)
- Mitigation of air pollution by greenness: A narrative review. (2018) (42)
- Advantages and limits of ADAMTS13 testing in thrombotic thrombocytopenic purpura. (2008) (42)
- Treatment of von Willebrand disease (1998) (42)
- Transmission of parvovirus B19 by coagulation factor concentrates exposed to 100 degrees C heat after lyophilization. (1997) (42)
- Outcome of Treatment of Deep-Vein Thrombosis with Urokinase: Relationship to Dosage, Duration of Therapy, Age of the Thrombus and Laboratory Changes (1984) (42)
- Tissue plasminogen activator antigen is strongly associated with myocardial infarction in young women (2005) (42)
- Desmopressin: a nontransfusional hemostatic agent. (1990) (42)
- Effects of Hirudin on Activated Partial Thromboplastin Time Determined with Ten Different Reagents (1993) (42)
- Failure of recombinant activated factor VII during surgery in a hemophiliac with high-titer factor VIII antibody. (1991) (42)
- Lupus anticoagulants and their relationship with the inhibitors against coagulation factor VIII: considerations on the differentiation between the 2 circulating anticoagulants. (2005) (42)
- High Plasma Levels of Protein C Activity and Antigen in the Nephrotic Syndrome (1986) (42)
- Immune Status of Asymptomatic HIV-Infected Hemophiliacs: Randomized, Prospective, Two-Year Comparison of Treatment with a High-Purity or an Intermediate-Purity Factor VIII Concentrate (1992) (41)
- Storage Pool Disease: Comparative Fluorescence Microscopical, Cytochemical and Biochemical Studies on Amine‐Storing Organelles of Human Blood Platelets (1979) (41)
- Association and Functional Analyses of MEF2A as a Susceptibility Gene for Premature Myocardial Infarction and Coronary Artery Disease (2009) (41)
- Prevention of hemoperitoneum during ovulation by oral contraceptives in women with type III von Willebrand disease and afibrinogenemia. Case reports. (1991) (41)
- Genetic risk stratification to reduce inhibitor development in the early treatment of hemophilia A: a SIPPET analysis. (2017) (41)
- Value of Hu antibody determinations in the follow-up of paraneoplastic neurologic syndromes (2004) (41)
- Patient preferences and willingness to pay for different options of anticoagulant therapy (2013) (41)
- Comparison of Functional Assays for Protein S: European Collaborative Study of Patients with Congenital and Acquired Deficiency (1993) (41)
- Venous thrombosis: the history of knowledge (2002) (40)
- TT virus is present in a high frequency of Italian hemophilic patients transfused with plasma-derived clotting factor concentrates. (1999) (40)
- Desmopressin and blood loss after cardiac surgery (1993) (40)
- Post-mortem findings in vaccine-induced thrombotic thrombocytopenia (2021) (40)
- Hemolytic uremic syndrome in adults. (1980) (40)
- Hyper‐responsiveness to DDAVP for patients with type I von Willebrand's disease and normal intra‐platelet von Willebrand factor (1988) (39)
- In vitro effects of picotamide on human platelet aggregation, the release reaction and thromboxane B2 production. (1991) (39)
- Plasma-derived versus recombinant factor VIII concentrates for the treatment of haemophilia A: plasma-derived is better. (2010) (39)
- Hyperhomocysteinemia as a risk factor for deep-vein thrombosis. (1996) (39)
- Kreuth III: European consensus proposals for treatment of haemophilia with coagulation factor concentrates (2014) (39)
- Protein C Antigen During Pregnancy, Delivery and Puerperium (1984) (39)
- Prospective study of the evaluation of hepatitis C virus infectivity in a high‐purity, solvent/detergent‐treated factor VIII concentrate: parallel evaluation of other markers for lipid‐enveloped and non‐lipid‐ enveloped viruses. (1993) (39)
- The international normalized ratio to prioritize patients for liver transplantation: problems and possible solutions. (2008) (39)
- Prevalence of Infection with the Hepatitis C Virus among Italian Hemophiliacs before and after the Introduction of Virally Inactivated Clotting Factor Concentrates: A Retrospective Evaluation (1994) (39)
- TTP and ADAMTS 13 : When Is Testing Appropriate ? (2007) (39)
- Identification of genetic risk variants for deep vein thrombosis by multiplexed next-generation sequencing of 186 hemostatic/pro-inflammatory genes (2012) (39)
- Long‐term safety and feasibility of arteriovenous fistulae as vascular accesses in children with haemophilia: a prospective study (2003) (39)
- Platelet von willebrand factor abnormalities in myeloproliferative syndromes (1995) (39)
- Activation of the contact system and inflammation after thrombolytic therapy in patients with acute myocardial infarction. (2004) (39)
- Naturally occurring anticoagulants and bone marrow transplantation: plasma protein C predicts the development of venocclusive disease of the liver. (1993) (39)
- Detection of the prethrombotic state due to procoagulant imbalance (1992) (38)
- Plasma levels of activated protein C in healthy subjects and patients with previous venous thromboembolism: relationships with plasma homocysteine levels. (1998) (38)
- A Type 2b von Willebrand Disease Mutation (lle546→Val) Associated with an Unusual Phenotype (1997) (38)
- Multicentric Evaluation of a New PT Reagent Based on Recombinant Human Tissue Factor and Synthetic Phospholipids (1994) (38)
- MPL and JAK2 exon 12 mutations in patients with the Budd-Chiari syndrome or extrahepatic portal vein obstruction. (2008) (38)
- Nonneutralizing antibodies against factor VIII and risk of inhibitor development in severe hemophilia A. (2017) (38)
- The risk of first venous thromboembolism during pregnancy and puerperium in double heterozygotes for factor V Leiden and prothrombin G20210A (2008) (38)
- Clinical and molecular characterization of 6 patients affected by severe deficiency of coagulation factor V: Broadening of the mutational spectrum of factor V gene and in vitro analysis of the newly identified missense mutations. (2003) (38)
- A variant of von Willebrand's disease characterized by recessive inheritance and missing triplet structure of von Willebrand factor multimers (1983) (38)
- Innovative Pharmacological Therapies for the Hemophilias Not Based on Deficient Factor Replacement (2016) (38)
- Changes in bleeding patterns in von Willebrand disease after institution of long-term replacement therapy: results from the von Willebrand Disease Prophylaxis Network (2015) (38)
- The History of Hemophilia (2014) (38)
- Carrier detection in hemophilia A: a cooperative international study. II. The efficacy of a universal discriminant. (1986) (38)
- Autosomal recessive deficiencies of coagulation factors. (2001) (37)
- Early-onset ischaemic stroke: Analysis of 58 polymorphisms in 17 genes involved in methionine metabolism (2010) (37)
- Liver disease, coagulopathies and transfusion therapy. (2013) (37)
- Status of Present and Candidate International Reference Preparations (IRP) of Thromboplastin for the Prothrombin Time (1993) (37)
- Multicenter Comparison of Five Functional and Two Immunological Assays for Protein C (1987) (37)
- The genetic basis of coronary artery disease: from candidate genes to whole genome analysis. (2008) (37)
- Efficacy and safety of highly purified, doubly virus‐inactivated VWF/FVIII concentrates in inherited von Willebrand’s disease: results of an Italian cohort study on 120 patients characterized by bleeding severity score (2010) (37)
- Evaluation of prophylactic replacement therapy in haemophilia B. (2009) (37)
- Screening test for thrombophilic patients: which tests, for which patient, by whom, when, and why? (1998) (37)
- Investigation of a case of subtype IIC von Willebrand disease: Characterization of the variability of this subtype (1986) (36)
- Congenital afibrinogenemia: intracellular retention of fibrinogen due to a novel W437G mutation in the fibrinogen Bbeta-chain gene. (2003) (36)
- Association between particulate air pollution and venous thromboembolism: A systematic literature review. (2016) (36)
- An Enzyme Immunoassay (ELISA) for the Quantitation of Human Factor VII (1986) (36)
- Von Willebrand factor: another janus-faced hemostasis protein. (2008) (36)
- Thrombomodulin Is a Cofactor for Thrombin Degradation of Recombinant Single-Chain Urokinase Plasminogen Activator "In Vitro" and in a Perfused Rabbit Heart Model (1992) (36)
- Source of Factor VIII Replacement (PLASMATIC OR RECOMBINANT) and Incidence of Inhibitory Alloantibodies in Previously Untreated Patients with Severe Hemophilia a: The Multicenter Randomized Sippet Study (2015) (35)
- Prothrombin Fragment 1+2 and Intensity of Treatment with Oral Anticoagulants (1991) (35)
- Mechanisms, markers and management of coagulation activation. (1994) (35)
- L-Asparaginase Lowers Protein C Antigen (1984) (35)
- Significance of plasma fibrinopeptide A and high molecular weight fibrinogen in patients with liver cirrhosis (1982) (35)
- The hemophilias: progress and problems. (1999) (35)
- Relatively Poor Performance of Clinical Laboratories for DNA Analyses in the Detection of Two Thrombophilic Mutations – A Cause for Concern (2002) (35)
- The role of the spleen in regulating the plasma levels of factor VIII--von Willebrand's factor after DDAVP. (1982) (34)
- Solvent/detergent plasma for prevention of bleeding in recessively inherited coagulation disorders: dosing, pharmacokinetics and clinical efficacy. (2006) (34)
- Sustained correction of the bleeding time in an afibrinogenaemic patient after infusion of fresh frozen plasma (1992) (34)
- New antiplatelet agents: why they are needed. (2009) (34)
- Antibody to hepatitis C virus after a vapour-heated factor VIII concentrate. The Study Group of the Fondazione dell'Emofilia. (1990) (34)
- Effects of Oral Contraceptives and Obesity on Protein C Antigen (1985) (34)
- The increase with age of the components of the tissue factor coagulation pathway is gender-dependent. (1995) (34)
- Myocardial infarction in the young: a sex-based comparison (2007) (34)
- Adverse clinical events and mortality during hospitalization and 3 months after discharge in cognitively impaired elderly patients. (2013) (33)
- Molecular genetic analysis of severe coagulation factor XI deficiency in six Italian patients. (2004) (33)
- Expression studies on a novel type 2B variant of the von Willebrand factor gene (R1308L) characterized by defective collagen binding (2005) (33)
- Early presence of activated ('exhausted') platelets in malignant tumors (breast adenocarcinoma and malignant melanoma). (1989) (33)
- Fibrinogen Milano II: A Congenital Dysfibrinogenaemia Associated with Juvenile Arterial and Venous Thrombosis (1986) (33)
- Recombinant Tissue Factor as Substitute for Conventional Thromboplastin in the Prothrombin Time Test (1992) (33)
- Homozygous protein C deficiency with moderately severe clinical symptoms. (1986) (33)
- Short-term Evaluation of Synovectomy in Haemophilia (1972) (33)
- Factor VII Deficiency: Immunological Characterization of Genetic Variants and Detection of Carriers (1981) (33)
- Low Levels of the Anticoagulant Activity of Protein C in Patients with Chronic Renal Insufficiency: an Inhibitor of Protein C Is Present in Uremic Plasma (1991) (33)
- A systematic overview of the first pasteurised VWF/FVIII medicinal product, Haemate®P/ Humate®‐P: History and clinical performance (2008) (33)
- The natural mutation by deletion of Lys9 in the thrombin A‐chain affects the pKa value of catalytic residues, the overall enzyme's stability and conformational transitions linked to Na+ binding (2006) (32)
- Feasibility of prophylaxis and immune tolerance induction regimens in haemophilic children using fully implantable central venous catheters (2008) (32)
- Arg2074Cys missense mutation in the C2 domain of factor V causing moderately severe factor V deficiency: molecular characterization by expression of the recombinant protein. (2003) (32)
- Thrombotic Thrombocytopenic Purpura: A Simpler Diagnosis at last? (1999) (32)
- ADAMTS13 content in plasma‐derived factor VIII/von Willebrand factor concentrates (2013) (32)
- Prothrombin A19911G polymorphism and the risk of venous thromboembolism (2006) (32)
- A partial factor V deficiency in anticoagulated lyophilized plasmas has been identified as a cause of the international normalized ratio discrepancy in the external quality assessment scheme. (1995) (32)
- Analysis of Iranian patients allowed the identification of the first truncating mutation in the fibrinogen Bbeta-chain gene causing afibrinogenemia. (2002) (32)
- Proteolysis of von Willebrand factor is decreased in acute promyelocytic leukaemia by treatment with all‐trans‐retinoic acid (1996) (32)
- No effect of polymorphisms in prothrombotic genes on the risk of myocardial infarction in young adults without cardiovascular risk factors (2005) (32)
- Sustained suppression of hepatitis C virus by interferon and ribavirin in hemophilic patients not responding to interferon monotherapy. (2002) (32)
- Afibrinogenemia: first identification of a splicing mutation in the fibrinogen gamma chain gene leading to a major gamma chain truncation. (2000) (32)
- Characterization of fibrinogen Milano I: amino acid exchange gamma 330 Asp----Val impairs fibrin polymerization. (1986) (31)
- The hemostatic system through aging and menopause (2009) (31)
- Spontaneous platelet aggregation during pregnancy in a patient with von Willebrand disease type IIB can be blocked by monoclonal antibodies to both platelet glycoproteins Ib and IIb/IIIa (1990) (31)
- Management of cerebral and splanchnic vein thrombosis associated with thrombocytopenia in subjects previously vaccinated with Vaxzevria (AstraZeneca): a position statement from the Italian Society for the Study of Haemostasis and Thrombosis (SISET). (2021) (31)
- New concepts for anticoagulant therapy in persons with hemophilia. (2016) (31)
- Factor VIII and chronic renal failure. (1977) (31)
- A novel two base pair deletion in the factor V gene associated with severe factor V deficiency (2000) (31)
- DDAVP shortens the prolonged bleeding times of patients with severe von Willebrand disease treated with cryoprecipitate. Evidence for a mechanism of action independent of released von Willebrand factor. (1989) (30)
- AIDS, hepatitis and hemophilia in the 1980s: memoirs from an insider (2003) (30)
- Desmopressin: Twenty Years After (1997) (30)
- Antithrombin Milano, Single Amino Acid Substitution at the Reactive Site, Arg393 to Cys (1988) (30)
- Low-molecular-weight heparins and cancer: Focus on antitumoral effect (2015) (30)
- Nervous Regulation of Factor‐VIII Levels in Man (1971) (30)
- Interaction Between the G 20210 A Mutation of the Prothrombin Gene and Oral Contraceptive Use in Deep Vein Thrombosis (1999) (30)
- Tissue factor in human coronary atherosclerotic plaques. (2000) (29)
- Increased production of platelet thromboxane B2 in non‐insulin‐dependent diabetes. Relationship to vascular complications (1984) (29)
- Profound alterations of the multimeric structure of von Willebrand factor in a patient with malignant lymphoma (1985) (29)
- Global coagulation in myeloproliferative neoplasms (2013) (29)
- Laboratory detection of inherited thrombophilia: a historical perspective. (2005) (29)
- Marburg I polymorphism of factor VII-activating protease and risk of venous thromboembolism. (2006) (29)
- The Measurement of Multifactorial Thrombophilia (2002) (29)
- Von Willebrand factor contaminating porcine factor VIII concentrate (Hyate: C) causes platelet aggregation (1986) (29)
- SIPPET: methodology, analysis and generalizability (2017) (29)
- Molecular and functional characterization of a natural homozygous Arg67His mutation in the prothrombin gene of a patient with a severe procoagulant defect contrasting with a mild hemorrhagic phenotype. (2002) (29)
- Antithrombin Milano: a new variant with monomeric and dimeric inactive antithrombin III. (1985) (28)
- Autoantibodies against the endothelial receptor of protein C are associated with acute myocardial infarction in young women (2005) (28)
- Recent progress in the pathophysiology of fibrinogen. (1995) (28)
- A Proposed Scheme for Calibration of International Reference Preparations of Thromboplastin for the Prothrombin Time (1995) (28)
- Von Willebrand factor (Vonvendi®): the first recombinant product licensed for the treatment of von Willebrand disease (2016) (28)
- HLA Antigens and Factor VIII Antibody in Classic Hemophilia (1981) (28)
- High rates of hepatitis G virus infection in multitransfused patients with hemophilia. (1997) (28)
- EVALUATION OF A FULLY AUTOMATED CENTRIFUGAL ANALYSER FOR ITS PERFORMANCE OF HEMOSTASIS TESTS (1987) (28)
- Type I von Willebrand disease, subtype ‘platelet low’: decreased platelet adhesion can be explained by low synthesis of von Willebrand factor in endothelial cells (1993) (28)
- Hyperprothrombinemia may result in acquired activated protein C resistance (2000) (28)
- Advances in the genetics and treatment of von Willebrand disease. (2002) (28)
- The complex differential diagnosis between thrombotic thrombocytopenic purpura and the atypical hemolytic uremic syndrome: Laboratory weapons and their impact on treatment choice and monitoring. (2015) (27)
- Coexistence of a novel homozygous nonsense mutation in exon 13 of the factor V gene with the homozygous Leiden mutation in two unrelated patients with severe factor V deficiency (2001) (27)
- Plasma factor VII levels are influenced by a polymorphism in the promoter region of the FVII gene (1996) (27)
- E-learning in order to improve drug prescription for hospitalized older patients: a cluster-randomized controlled study. (2016) (27)
- Uncertain thrombophilia markers (2016) (27)
- Interactions between genotype and phenotype in bleeding and thrombosis (2008) (27)
- Hypercoagulability and hyperfibrinolysis in patients with melanoma. (1996) (27)
- Intramuscular anti‐D immunoglobulins for home treatment of chronic immune thrombocytopenic purpura (1992) (27)
- Simultaneous genotyping of coagulation factor XI type II and type III mutations by multiplex real-time polymerase chain reaction to determine their prevalence in healthy and factor XI-deficient Italians (2008) (27)
- Expression studies of missense mutations p.D141Y, p.C275S located in the propeptide of von Willebrand factor in patients with type 3 von Willebrand disease (2008) (27)
- Resistance to activated protein C in unselected patients with arterial and venous thrombosis (1997) (27)
- Timing and severity of inhibitor development in recombinant versus plasma‐derived factor VIII concentrates: a SIPPET analysis (2018) (27)
- Low incidence of bleeding from HIV‐related thrombocytopenia in drug addicts and hemophiliacs: Implications for therapeutic strategies (1990) (27)
- Markers of Hypercoagulability in Patients with Hemophilia B Given Repeated, Large Doses of Factor IX Concentrates during and after Surgery (1994) (27)
- Direct oral anticoagulants and venous thromboembolism (2016) (26)
- The European standards of Haemophilia Centres. (2014) (26)
- Factor VIII clotting activity (1999) (26)
- A rare inherited coagulation disorder: Combined homozygous factor VII and factor X deficiency (2004) (26)
- Multicenter Comparison of von Willebrand Factor Multimer Sizing Techniques (1985) (26)
- Presurgical pharmacokinetic analysis of a von Willebrand factor/factor VIII (VWF/FVIII) concentrate in patients with von Willebrand’s disease (VWD) has limited value in dosing for surgery (2011) (26)
- Half-life extension technologies for haemostatic agents. (2014) (26)
- Venocclusive disease of the liver after bone marrow transplantation: the role of hemostasis. (1997) (26)
- Platelet von Willebrand factor assay: results using two methods for platelet lysis. (1990) (26)
- Poor Relationship between Phenotypes of Protein S Deficiency and Mutations in the Protein S Alpha Gene (1999) (26)
- The Effect of Instrumentation on Thromboplastin Calibration (1992) (26)
- Nomenclature of Quantities and Units in Thrombosis and Haemostasis (Recommendation 1993) (1994) (26)
- Oral Contraceptives Are a Risk Factor for Cerebral Vein Thrombosis (1996) (26)
- Common variants in the haemostatic gene pathway contribute to risk of early-onset myocardial infarction in the Italian population (2011) (26)
- Mutations in hemophilia Bm occur at the Arg180-Val activation site or in the catalytic domain of factor IX. (1990) (26)
- Immune status of human immunodeficiency virus seropositive and seronegative hemophiliacs infused for 3.5 years with recombinant factor VIII. The Kogenate Study Group. (1994) (25)
- Glanzmann thrombasthenia and Bernard-Soulier syndrome in south Iran. (2005) (25)
- Calibration of Local Systems with Lyophilized Calibrant Plasmas Improves the Interlaboratory Variability of the INR in the Italian External Quality Assessment Scheme (1999) (25)
- In Vivo Thrombin Generation and Activity During and After Intravenous Infusion of Heparin or Recombinant Hirudin in Patients With Unstable Angina Pectoris (2000) (25)
- Factor V (Arg 506-->Gln) mutation in young survivors of myocardial infarction. (1996) (25)
- Point-of-care coagulation monitors calibrated for the international normalized ratio for cirrhosis (INRliver) can help to implement the INRliver for the calculation of the MELD score. (2009) (25)
- Enhancement of plasminogen activator by vasopressin and adrenaline: a role of cyclic AMP? (1974) (25)
- New therapies for von Willebrand disease. (2019) (25)
- The significance of protein C antigen in acute and chronic liver biliary disease. (1985) (25)
- The In Vitro Production of Thromboxane B2 by Platelets of Diabetic Patients Is Normal at Physiological Concentrations of lonized Calcium (1993) (25)
- Laboratory screening of thrombophilia. Evaluation of the diagnostic efficacy of a global test to detect congenital deficiencies of the protein C anticoagulant pathway (1998) (25)
- Thrombophilic Mutations in Iran (2000) (24)
- Gender difference in drug use in hospitalized elderly patients. (2015) (24)
- The Outbreak of Hepatitis A in Italian Patients with Hemophilia: Facts and Fancies (1994) (24)
- A Mutation in the Protein S Pseudogene Is Linked to Protein S Deficiency in a Thrombophilic Family (1989) (24)
- Effect on blood coagulation of massive intravascular haemolysis. (1968) (24)
- A randomized, placebo-controlled, blind anti-AIDS clinical trial : safety and immunogenicity of a specific anti-IFNα immunization (1994) (24)
- An increased factor VIII antigen as an indicator of endothelial damage in measles. (1979) (24)
- Reduced Effect of Exercise and DDAVP on Factor VIII-von Willebrand Factor and Plasminogen Activator after Sequential Application of Both the Stimuli (1984) (24)
- Adherence to antibiotic treatment guidelines and outcomes in the hospitalized elderly with different types of pneumonia. (2015) (24)
- Changes of Prothrombin Fragment 1+2 (F 1+2) as a Function of Increasing Intensity of Oral Anticoagulation (1998) (24)
- von Willebrand factor collagen binding assay in von Willebrand disease type 2A, 2B, and 2M (2006) (24)
- The natural history of hepatitis C virus infection in Italian patients with von Willebrand's disease: a cohort study. (2006) (24)
- Present and future challanges in the treatment of haemophilia: a clinician's perspective. (2013) (24)
- High efficacy of combined therapy with pegylated interferon plus ribavirin in patients with hemophilia and chronic hepatitis C. (2006) (24)
- Prescription drug use among older adults in Italy: a country-wide perspective. (2014) (24)
- A Natural Prothrombin Mutant Reveals an Unexpected Influence of A-chain Structure on the Activity of Human α-Thrombin* (2004) (24)
- Platelet reactive conformation and multimeric pattern of von Willebrand factor in acquired thrombotic thrombocytopenic purpura during acute disease and remission (2011) (23)
- Porcine recombinant factor VIII: an additional weapon to handle anti-factor VIII antibodies. (2017) (23)
- The Health and Economic Burden of Air Pollution. (2015) (23)
- Abnormal Protac-induced coagulation inhibition chromogenic assay results are associated with an increased risk of recurrent venous thromboembolism (2010) (23)
- Comparison of Health Care Resource Utilization by Immigrants Versus Native Elderly People (2016) (23)
- Mechanistic studies on ADAMTS13 catalysis. (2008) (23)
- Results of a Multicenter Study Assessing the Status of Standardization of a Recombinant Thromboplastin for the Control of Oral Anticoagulant Therapy (1994) (23)
- Red cells playing as activated platelets in thalassemia intermedia (2010) (23)
- PLASMA LEVELS OF THE VON WILLEBRAND FACTOR-CLEAVING PROTEASE IN PHYSIOLOGICAL AND PATHOLOGICAL CONDITIONS IN CHILDREN (2002) (23)
- Transmission of hepatitis G virus in patients with angioedema treated with steam‐heated plasma concentrates of C1 inhibitor (1998) (23)
- Pharmacokinetic properties of IB1001, an investigational recombinant factor IX, in patients with haemophilia B: repeat pharmacokinetic evaluation and sialylation analysis (2012) (23)
- Severe factor V deficiency: exon skipping in the factor V gene causing a partial deletion of the C1 domain (2003) (23)
- Role for platelet von willebrand factor in supporting platelet‐vessel wall interactions in von willebrand disease (1989) (23)
- Management of Bleeding Associated with New Oral Anticoagulants (2015) (23)
- Proteolysis of von Willebrand factor after thrombolytic therapy in patients with acute myocardial infarction (1992) (23)
- In vitro and ex vivo effects of indobufen on human platelet aggregation, the release reaction and thromboxane B2 production. (1987) (23)
- Familial aggregation of early-onset myocardial infarction. (2010) (22)
- Multimeric pattern of plasma and platelet von willebrand factor is normal in uremic patients (1993) (22)
- Adhesive properties of the carbohydrate-modified von Willebrand factor (CHO-vWF). (1988) (22)
- Hemophilia in the 1990s: principles of management and improved access to care. (1992) (22)
- Progress in the contemporary management of hemophilia: The new issue of patient aging. (2017) (22)
- Allele Frequency of CYP2C9 Gene Polymorphisms in Iran (2002) (22)
- Development of factor VIII antibody in haemophilic monozygotic twins. European Study Group of Factor VIII Antibody. (2009) (22)
- How to evaluate the influence of blood collection systems on the international sensitivity index. Protocol applied to two new evacuated tubes and eight coagulometer/thromboplastin combinations. (2002) (22)
- Hemostatic alterations are unrelated to the stage of tumor in untreated malignant melanoma and breast carcinoma. (1985) (22)
- Potentially Inappropriate Medications, Drug–Drug Interactions, and Anticholinergic Burden in Elderly Hospitalized Patients: Does an Association Exist with Post-Discharge Health Outcomes? (2020) (22)
- Missense or splicing mutation? The case of a fibrinogen Bbeta-chain mutation causing severe hypofibrinogenemia. (2004) (22)
- Prediction of factor VIII inhibitor development in the SIPPET cohort by mutational analysis and factor VIII antigen measurement (2018) (22)
- Fibrotic interstitial lung diseases and air pollution: a systematic literature review (2020) (22)
- Activated partial thromboplastin time (APTT). New indications for an old test? (2006) (21)
- Thrombotic thrombocytopenic purpura and the hemolytic uremic syndrome: much progress and many remaining issues. (2007) (21)
- Afibrinogenemia: first identification of a splicing mutation in the fibrinogen gamma chain gene leading to a major gamma chain truncation (2000) (21)
- Prevalence, characteristics and treatment of chronic pain in elderly patients hospitalized in internal medicine wards. (2018) (21)
- Detection of circulating released platelets after renal transplantation. (1982) (21)
- Poor Comparability of Prothrombin Fragment 1 + 2 Values Measured by Two Commercial ELISA Methods: Influence of Different Anticoagulants and Standards (1994) (21)
- Immunological Heterogeneity of Haemophilia B: a Multicentre Study of 98 Kindreds (1978) (21)
- Prophylaxis of venous thromboembolism in elderly patients with multimorbidity (2013) (21)
- Sex-Differences in the Pattern of Comorbidities, Functional Independence, and Mortality in Elderly Inpatients: Evidence from the RePoSI Register (2019) (21)
- Emergency department visits in older people: pattern of use, contributing factors, geographical differences and outcomes (2017) (21)
- Management of antithrombotic therapy for acute coronary syndromes and atrial fibrillation in patients with hemophilia (2012) (21)
- The never ending success story of tranexamic acid in acquired bleeding (2020) (21)
- State of Care for Hemophilia in Pediatric Patients (2002) (21)
- Apolipoprotein(a) Kringle-IV Type 2 Copy Number Variation Is Associated with Venous Thromboembolism (2016) (21)
- A survey of inherited thrombotic syndromes in italy (1989) (21)
- Appropriateness of oral anticoagulant therapy prescription and its associated factors in hospitalized older people with atrial fibrillation (2018) (21)
- Ticlopidine Facilitates the Deaggregation of Human Platelets Aggregated by Thrombin (1994) (20)
- Comparative evaluation of the pharmacokinetics of three monoclonal factor VIII concentrates. (1991) (20)
- Accelerated schedule of hepatitis B vaccination in patients with hemophilia (1993) (20)
- Telemedicine and telerehabilitation: current and forthcoming applications in haemophilia. (2019) (20)
- Erratum: The hemophilias - From royal genes to gene therapy (New England Journal of Medicine (June 7, 2001) 344 (1773-9)) (2001) (20)
- Thromboembolism Following Prothrombin Complex Concentrates and Major Surgery in Severe Liver Disease (1978) (20)
- Results of a collaborative study for fibrinogen measurement. Evidence that the use of a common calibrator improves interlaboratory agreement (1994) (20)
- Antithrombin III Milano 2: a single base substitution in the thrombin binding domain detected with PCR and direct genomic sequencing. (1989) (20)
- Ways to reduce the risk of transmission of viral infections by plasma and plasma products. A comparison of methods, their advantages and disadvantages. (1988) (20)
- Role of synovectomy in hemophilic arthropathy. (1977) (20)
- Imatinib and polypharmacy in very old patients with chronic myeloid leukemia: effects on response rate, toxicity and outcome (2016) (20)
- Effect of Des-Amino-D-Arginine Vasopressin (DDAVP) on Plasma Levels of Platelet and Endothelial Cell Release Products (1983) (20)
- Disability, and not diabetes, is a strong predictor of mortality in oldest old patients hospitalized with pneumonia. (2018) (19)
- CONCENTRATES OF CLOTTING-FACTOR IX (1976) (19)
- Premature termination codon mutations in the von Willebrand factor gene are associated with allele-specific and position-dependent mRNA decay (2010) (19)
- Desmopressin: an historical introduction (2007) (19)
- Inflammatory and prothrombotic parameters in normotensive non-diabetic obese women: effect of weight loss obtained by gastric banding (2012) (19)
- Adjunct agents for bleeding (2014) (19)
- Thromboembolic incidence with transiently elevated levels of coagulation factors in patients with von Willebrand disease treated with VWF:FVIII concentrate during surgery (2014) (19)
- Multicenter Evaluation of Three Commercial Methods for Measuring Protein S Antigen (1992) (19)
- Non‐thrombotic‐, non‐inhibitor‐associated adverse reactions to coagulation factor concentrates for treatment of patients with hemophilia and von Willebrand’s disease: a systematic review of prospective studies (2012) (19)
- Multiple dental extractions with a new prothrombin complex concentrate in two patients with factor VIII inhibitors. (1979) (19)
- The elusive pathogenesis of von Willebrand disease Vicenza. (2002) (19)
- The European Haemophilia Network (EUHANET). (2014) (19)
- Fc-fusion technology and recombinant FVIII and FIX in the management of the hemophilias (2014) (19)
- Desmopressin: a nontransfusional treatment of hemophilia and von Willebrand disease. (1992) (19)
- Decrease and rapid recovery of protein C after plasma exchange (1986) (19)
- Analysis of Arg834Gln and Val902Glu type 2A von Willebrand disease mutations: studies with recombinant von Willebrand factor and correlation with patient characteristics. (1996) (19)
- Tailoring hemostatic therapies to lower inhibitor development in previously untreated patients with severe hemophilia A (2016) (19)
- More on: high thrombin generation and the risk of recurrent venous thromboembolism (2009) (19)
- Determinants of plasma factor VIIa levels in humans. (1995) (19)
- A Simplified Procedure for Thromboplastin Calibration -The Usefulness of Lyophilized Plasmas Assessed in a Collaborative Study (1996) (18)
- Type II H von willebrand disease: New structural abnormality of plasma and platelet von willebrand factor in a patient with prolonged bleeding time and borderline levels of ristocetin cofactor activity (1989) (18)
- INDOBUFEN VERSUS ASPIRIN PLUS DIPYRIDAMOLE AFTER CORONARY-ARTERY BYPASS-SURGERY (1991) (18)
- Direct Proof of Extreme Lyonization as a Cause of Low Factor VIII Levels in Females (1978) (18)
- Warfarin and acenocoumarol dose requirements according to CYP2C9 genotyping in North‐Italian patients (2003) (18)
- Markers of procoagulant imbalance in patients with localized melanomas and autoimmune disorders (1993) (18)
- Prognostic value of estimated glomerular filtration rate in hospitalized elderly patients (2014) (18)
- Studies on hemophilia A in Sardinia bearing on the problems of multiple allelism, carrier detection, and differential mutation rate in the two sexes. (1984) (18)
- Human Platelet Aggregation and Release Reaction Induced by Platelet Activating Factor (PAF-Acether) – Effects of Acetylsalicylic Acid and External Ionized Calcium (1985) (18)
- Kreuth V initiative: European consensus proposals for treatment of hemophilia using standard products, extended half-life coagulation factor concentrates and non-replacement therapies (2020) (18)
- Molecular Mapping of the Chloride-binding Site in von Willebrand Factor (VWF) (2006) (18)
- Active platelet‐binding conformation of plasma von Willebrand factor in young women with acute myocardial infarction (2010) (18)
- A Small Animal Model for Electrocardiographic Abnormalities Observed After An Experimental Subarachnoid Hemorrhage (18)
- Specificity of hepatitis C antibody ELISA in patients with haemophilia (1990) (18)
- Inherited factors in thrombosis. (1988) (18)
- Kreuth IV: European consensus proposals for treatment of haemophilia with coagulation factor concentrates (2017) (18)
- High Prevalence of Serum Cryoglobulins in Multitransfused Hemophilic Patients With Chronic Hepatitis C (1998) (18)
- Determination of pharmacokinetics of replacement factor VIII. (1990) (18)
- Increased Fibrinopeptide A after Prothrombin Complex Concentrates (1980) (18)
- Improving primary care in Europe beyond COVID-19: from telemedicine to organizational reforms (2020) (18)
- Under the auspices of the Italian Association for the Study of Liver Diseases (AISF) and the Italian Society of Internal Medicine (SIMI) (2016) (17)
- Miracle of haemophilia drugs: Personal views about a few main players (2018) (17)
- Antibodies to factor VIII-von Willebrand factor in congenital and acquired von Willebrand's disease. (1984) (17)
- Haemophilia B is clinically less severe than haemophilia A: further evidence. (2018) (17)
- Progression to AIDS among Italian HIV‐seropositive haemophiliacs (1991) (17)
- Secondary Long-Term Prophylaxis in Severe Patients with von Willebrand’s Disease: An Italian Cohort Study. (2005) (17)
- Modifiers of clinical phenotype in severe congenital hemophilia. (2017) (17)
- Implementation of the Frailty Index in hospitalized older patients: Results from the REPOSI register. (2018) (17)
- α1-antitrypsin therapy in a case of thrombotic thrombocytopenic purpura (1995) (17)
- Quality assurance program for whole blood prothrombin time-international normalized ratio point-of-care monitors used for patient self-testing to control oral anticoagulation. (2004) (17)
- Oral anticoagulant use in octogenarian European patients with atrial fibrillation: A subanalysis of PREFER in AF. (2017) (17)
- [Hemostasis and liver disease]. (1981) (17)
- Uncertain times for research on hemophilia and allied disorders (2005) (17)
- Effect of Abciximab on Prothrombin Activation and Thrombin Generation in Acute Coronary Syndromes Without ST-Segment Elevation: Global Utilization of Strategies to Open Occluded Coronary Arteries Trial IV in Acute Coronary Syndromes (GUSTO IV ACS) Italian Hematologic Substudy (2002) (17)
- Cholesterol-adjusted vitamin E serum levels are associated with cardiovascular events in patients with non-valvular atrial fibrillation. (2013) (17)
- Gly319 → Arg substitution in the dysfunctional prothrombin Segovia (1999) (17)
- Functional Assays of Protein C: Comparison of Two Snake-Venom Assays with Two Thrombin Assays (1988) (17)
- The hemostatic balance revisited through the lessons of mankind evolution (2008) (17)
- Air pollution levels and cardiovascular health: Low is not enough (2017) (17)
- A multicenter controlled, randomized, open trial of interferon alpha2b treatment of anti-human immunodeficiency virus-negative hemophilic patients with chronic hepatitis C. Hepatitis Study Group of the Association of Italian Hemophilia Centers. (1997) (17)
- Embryo implantation after assisted reproductive procedures and maternal thrombophilia (2003) (16)
- Primary hyperfibrinolysis: Facts and fancies. (2018) (16)
- Prognostic value of degree and types of anaemia on clinical outcomes for hospitalised older patients. (2017) (16)
- Management of von Willebrand disease in developing countries. (2005) (16)
- Homozygous 2bp Deletion in the Human Factor VII Gene: A Non-Lethal Mutation that Is Associated with a Complete Absence of Circulating Factor VII (2000) (16)
- Resistance to activated protein C mimicking dysfunctional protein C: diagnostic approach (1996) (16)
- Ageing successfully with haemophilia: A multidisciplinary programme (2018) (16)
- Protein S mRNA in Patients with Protein S Deficiency (1995) (16)
- VON WILLEBRAND FACTOR ABNORMALITIES IN TWO PATIENTS WITH URAEMIA (1988) (16)
- Frequency of Factor V Arg506 Gin in Italians (1996) (16)
- Novel investigations on the protective role of the FVIII/VWF complex in inhibitor development (2014) (16)
- Treatment of haemophilia: building on strength in the third millennium (2011) (16)
- Platelet functions after intravenous administration in man of cyclic-AMP and related drugs (1974) (16)
- Heated clotting factors and seroconversion for human immunodeficiency virus in three hemophilic patients. (1987) (16)
- Multicenter evaluation of a new chromogenic factor X assay in plasma of patients on oral anticoagulants. (1980) (16)
- Oxidized von Willebrand factor is efficiently cleaved by serine proteases from primary granules of leukocytes: divergence from ADAMTS‐13 (2011) (16)
- Alloantibodies in von Willebrand Disease (2017) (16)
- Role of the 2 adenine (g.11293_11294insAA) insertion polymorphism in the 3′ untranslated region of the factor VII (FVII) gene: molecular characterization of a patient with severe FVII deficiency (2005) (16)
- A contemporary look at FVIII inhibitor development: still a great influence on the evolution of hemophilia therapies (2018) (16)
- Electroblot and Immunoperoxidase Staining for Rapid Screening of the Abnormalities of the Multimeric Structure of von Willebrand Factor in von Willebrand’s Disease (1986) (16)
- Comorbidity does not mean clinical complexity: evidence from the RePoSI register (2019) (15)
- Association of a single nucleotide polymorphism of the NPR3 gene promoter with early onset ischemic stroke in an Italian cohort. (2013) (15)
- Management of orthopaedic surgery in rare bleeding disorders (2014) (15)
- Genetic characterization of patients with Bernard-Soulier syndrome and their relatives from Southern Iran (2007) (15)
- Does enhancement of oxidative stress markers mediate health effects of ambient air particles? (2014) (15)
- Prognostic value of hemostatic parameters after liver transplantation. (1992) (15)
- Treatment of hemophilia: recombinant factors only? No (2003) (15)
- Phenotypic and genetic analysis of a compound heterozygote for dys‐ and hypoprothrombinaemia (2003) (15)
- Virology of the Hepatitis A Epidemic in Italy (1994) (15)
- Diagnosis and management of acquired von Willebrand syndrome. (2003) (15)
- Appropriateness of antiplatelet therapy for primary and secondary cardio‐ and cerebrovascular prevention in acutely hospitalized older people (2017) (15)
- Coinheritance of the HR 2 Haplotype in the Factor V Gene Confers an Increased Risk of Venous Thromboembolism to Carriers of Factor V R 506 Q ( Factor V Leiden ) (1999) (15)
- Drug-drug interactions involving CYP3A4 and p-glycoprotein in hospitalized elderly patients. (2019) (15)
- Factor VIII activity as measured by an amidolytic assay compared with a one-stage clotting assay. (1986) (15)
- Standardization of the APC Resistance Test. Effects of Normalization of Results by Means of Pooled Normal Plasma (1998) (15)
- Advantages and limits of ADAMTS13 testing in the prognostic assessment of thrombotic thrombocytopenic purpura. (2012) (15)
- Desmopressin‐induced thrombocytopenia in type i platelet discordant von willebrand disease (1993) (15)
- Heterogeneity in type IIB von Willebrand disease: Two unrelated cases with no family history and mild abnormalities of ristocetin‐induced interaction between von willebrand factor and platelets (1986) (15)
- Bleeding symptoms in patients diagnosed as type 3 von Willebrand disease: Results from 3WINTERS‐IPS, an international and collaborative cross‐sectional study (2020) (15)
- Pain and Frailty in Hospitalized Older Adults (2020) (15)
- Pain and Frailty in Hospitalized Older Adults (2020) (15)
- Isolation of an abnormal protein C molecule from the plasma of a patient with thrombotic diathesis. (1988) (15)
- High Fibrinopeptide A (FPA) Levels in Acute Non-Lymphocytic Leukemia Are Reduced by Heparin Administration (1984) (15)
- Intracranial bleeding in haemophilia: a study of eleven cases. (1982) (14)
- The International Society for Thrombosis and Haemostasis owns its official journal: the future has begun! (2003) (14)
- Laboratory monitoring of replacement therapy for major surgery in von Willebrand disease (2017) (14)
- Effects of Factor VIII Concentrates on the Immune System of Patients with Hemophilia (1995) (14)
- Investigational drugs for coagulation disorders (2013) (14)
- Clinical evaluation of a fully automated chromogenic method for prothrombin time compared with a conventional coagulation method. (1984) (14)
- Laboratory Diagnosis of Lupus Anticoagulants (2002) (14)
- Familial Overexpression of β Antithrombin Caused by an Asn135Thr Substitution (1999) (14)
- Fibrin clot structure is affected by levels of particulate air pollution exposure in patients with venous thrombosis. (2016) (14)
- Thromboprophylaxis in the oldest old with atrial fibrillation: between Scylla and Charybdis. (2013) (14)
- PROTEIN C CONCENTRATES FOR THERAPEUTIC USE (1983) (14)
- Prevalence of type 2b ‘Malmö/New York’ von Willebrand disease in Italy: the role of von Willebrand factor gene conversion (2008) (14)
- Use of prophylaxis to prevent complications of hemophilia. (2001) (14)
- Systemic clotting activation by low-grade endotoxaemia in liver cirrhosis: a potential role for endothelial procoagulant activation. (1997) (14)
- Serum hepatitis B virus DNA detects cryptic hepatitis B virus infections in multitransfused hemophilic patients (1990) (14)
- Comorbidities in persons with haemophilia aged 60 years or more compared with age‐matched people from the general population (2018) (14)
- Monoclonal Antibodies Directed to the Calcium-Free Conformation of Human Protein S (1989) (14)
- The real value of thrombophilia markers in identifying patients at high risk of venous thromboembolism (2014) (14)
- von Willebrand disease in the 21st century: current approaches and new challenges (2009) (14)
- Benefits and limitations of extended plasma half-life factor VIII products in hemophilia A (2020) (14)
- Acquired storage pool disease in platelets during disseminated intravascular coagulation (1976) (14)
- High Levels of Tissue Factor Pathway Inhibitor in Patients with Nephrotic Proteinuria (1999) (14)
- Joint use of cardio-embolic and bleeding risk scores in elderly patients with atrial fibrillation. (2013) (14)
- Familial Overexpression of β Antithrombin Caused by an Asn135Thr Substitution (1999) (14)
- Integrated postural analysis in children with haemophilia (2014) (13)
- Risk factors for three-month mortality after discharge in a cohort of non-oncologic hospitalized elderly patients: Results from the REPOSI study. (2018) (13)
- Pattern of in‐hospital changes in drug use in the older people from 2010 to 2016 (2017) (13)
- Pattern of comorbidities and 1-year mortality in elderly patients with COPD hospitalized in internal medicine wards: data from the RePoSI Registry (2020) (13)
- Pattern of comorbidities and 1-year mortality in elderly patients with COPD hospitalized in internal medicine wards: data from the RePoSI Registry (2020) (13)
- Recurrent Late Fetal Death in Women with and without Thrombophilia (2002) (13)
- Low risk of transmission of the human immunodeficiency virus by a solvent‐detergent‐treated commercial factor VIII concentrate (1992) (13)
- Phenotype commitment in vascular smooth muscle cells derived from coronary atherosclerotic plaques: differential gene expression of endothelial nitric oxide synthase. (2009) (13)
- Liver transplantation in severe von Willebrand disease (1991) (13)
- New drugs for thromboprophylaxis in atrial fibrillation. (2012) (13)
- Living alone as an independent predictor of prolonged length of hospital stay and non-home discharge in older patients. (2018) (13)
- Familial dysfunctional protein C. (1986) (13)
- Relationship between atrial fibrillation and cognitive decline in individuals aged 80 and older. (2017) (13)
- Prophylaxis for adults with haemophilia: towards a personalised approach? (2012) (13)
- Pharmacogenetic aspects of the use of oral contraceptives and the risk of thrombosis. (2003) (13)
- Anti-alpha interferon immunization: safety and immunogenicity in asymptomatic HIV positive patients at high risk of disease progression. (1995) (13)
- Need for randomized trials in hemophilia (2006) (13)
- Noise and air pollution as triggers of hypertension. (2021) (13)
- Heightened proteolysis of the von Willebrand factor subunit in patients with von Willebrand disease hemizygous or homozygous for the C2362F mutation (2000) (13)
- Type 2A (IIH) von Willebrand disease is due to mutations that affect von Willebrand factor multimerization (2009) (13)
- Markers of hypercoagulability in cancer patients. (1997) (13)
- Progress in fibrinolysis (1975) (13)
- Platelet/von Willebrand factor inhibitors to the rescue of ischemic stroke. (2010) (13)
- Thalassemia trait and arterial thromboembolic events: a systematic review and a meta‐analysis of the literature (2011) (13)
- Continuous infusion of porcine factor VIII in patients with haemophilia A and high‐responding inhibitors: stability and clinical experience (2001) (13)
- Cellogel electrophoresis of haemoglobins. (1968) (13)
- A new variant of von Willebrand disease (type II I) with a normal degree of proteolytic cleavage of von Willebrand factor. (1992) (13)
- Identification of Four Novel Polymorphisms in the Aα and γ Fibrinogen Genes and Analysis of Association with Plasma Levels of the Protein (2001) (13)
- Treatment of Von Willebrand Disease (2001) (13)
- Summary report of the First International Conference on inhibitors in haemophilia A. (2017) (13)
- Repeated Release of the Tissue Factor Pathway Inhibitor (1994) (13)
- Changes in fibrinolysis in patients with localized tumors. (1990) (13)
- Understanding organ dysfunction in thrombotic thrombocytopenic purpura (2015) (13)
- Secondary long-term prophylaxis in von Willebrand disease: an Italian cohort study (2009) (12)
- Charge heterogeneity of human protein C revealed by isoelectric focusing in immobilized pH gradients (1985) (12)
- Inhibitors of factor VIII in hemophilia. (2009) (12)
- Letter: Enhanced factor VIII activity in von Willebrand's disease. (1974) (12)
- Identification of three candidate mutations causing type IIA von Willebrand disease using a rapid, nonradioactive, allele-specific hybridization method (1993) (12)
- The stigma of low opioid prescription in the hospitalized multimorbid elderly in Italy (2015) (12)
- Biochemical characterization of a recombinant von Willebrand factor (VWF) with combined type 2B and type 1 defects in the VWF gene in two patients with a type 2A phenotype of von Willebrand disease (2007) (12)
- Desmopressin in Bleeding Disorders (1993) (12)
- Hepatitis C virus/human immunodeficiency virus coinfection in hemophiliacs: high rates of sustained virologic response to pegylated interferon and ribavirin therapy (2009) (12)
- Haemophilia treatment protocols around the world: towards a consensus (1998) (12)
- Alloantibodies in congenital von Willebrand’s disease (1991) (12)
- Comparative analysis of the pivotal studies of extended half‐life recombinant FVIII products for treatment of haemophilia A (2021) (12)
- Mechanisms of Disease The Coagulopathy of Chronic Liver Disease (2011) (12)
- What is the importance of the 'small pool concept' in the preparation of fraciton I and cryoprecipitates for the prevention of post-transfusion hepatitis? (1980) (12)
- The Use of Plasma‐Derived Concentrates (2011) (12)
- Comparison of a functional assay for protein C with two immunoassays. (1985) (11)
- Acquired Storage Pool Disease in Myeloproliferative Disorders (1979) (11)
- Fine particulate: it matters (2010) (11)
- Choice and Outcomes of Rate Control versus Rhythm Control in Elderly Patients with Atrial Fibrillation: A Report from the REPOSI Study (2018) (11)
- Clinical and laboratory patterns of the haemolytic uraemic syndrome and thrombotic thrombocytopenic purpura in southern Iran (2006) (11)
- PRELIMINARY TRIAL OF CYCLOPHOSPHAMIDE IN THE MANAGEMENT OF HEMOPHILIACS WITH FACTOR VIII INHIBITORS * (1975) (11)
- Effect on Platelet Functions of Derivatives of Cyclic Nucleotides (1978) (11)
- Abnormalities of lymphocyte subsets are correlated with concentrate consumption in asymptomatic Italian hemophiliacs treated with concentrates made from American plasma (1984) (11)
- Determinants of plasma factor VIIa levels in humans (1995) (11)
- Recommended Protocol for the Study of the Ex Vivo Biological Effects of Virus-Inactivated Plasma Concentrates in Patients with von Willebrand Disease (1992) (11)
- INCREASED PROTEIN C AND FIBRINOPEPTIDE A CONCENTRATION IN PATIENTS WITH ANGINA (1988) (11)
- Conditions Influencing the Interaction of Asialo von Willebrand Factor with Human Platelets – The Effects of External Ionized Calcium Concentration and the Role of Arachidonate Pathway (1988) (11)
- Vasopressin Analogues (1987) (11)
- Effect of CIBA 13,437-Su on serum cholesterol and triglycerides, plasma fibrinogen, fibrinolysis and platelet adhesiveness in patient with ischemic hert disease. (1971) (11)
- Haematology clinic: Haemophilia A (2014) (11)
- Evolution of the European guidelines for the clinical development of factor VIII products: little progress towards improved patient management (2013) (11)
- Urokinase : basic and clinical aspects (1982) (11)
- Addressing current challenges in haemophilia care: consensus recommendations of a European Interdisciplinary Working Group (2005) (11)
- Circulating endothelial cells (CECs) and progenitors (CEPs) in severe haemophiliacs with different clinical phenotype (2009) (11)
- Expression of endothelial protein C receptor and thrombomodulin in human coronary atherosclerotic plaques. (2004) (11)
- Pediatric requirements in Europe stymie help for hemophilia (2014) (10)
- Dosing anticoagulant therapy with coumarin drugs: is genotyping clinically useful? No (2008) (10)
- Incidence and Determinants of Bleeding in Different Types of von Willebrand Disease: Results of the First Prospective Multicenter Study on 814 Italian Patients. (2007) (10)
- Patterns of changes of anti‐ADAMTS13 after plasma exchange (2006) (10)
- Prevalence of Mutant Factor V in Italian Patients with Hereditary Deficiencies of Antithrombin, Protein C or Protein S (1996) (10)
- Inappropriate prescription of benzodiazepines in acutely hospitalized older patients (2019) (10)
- Tailoring care to haemophilia patients' needs: which specialty and when? (2015) (10)
- Fibrinolysis in cholestatic jaundice. (1973) (10)
- Consistency of ADAMTS‐13 activity assays: a moderately optimistic view (2003) (10)
- The safety of pharmacologic options for the treatment of persons with hemophilia (2016) (10)
- Content and release of beta-thromboglobulin and platelet factor 4 in patients with qualitative platelet defects. (1979) (10)
- Biochemical characteristics of therapeutic plasma concentrates used in the treatment of von Willebrand disease. (1994) (10)
- A critical role for Gly25 in the B chain of human thrombin (2005) (10)
- Effect of abciximab on prothrombin activation and thrombin generation in patients with acute myocardial infarction also receiving reteplase. (2004) (10)
- Long‐term follow‐up of randomized trials of immediate versus deferred zidovudine in symptom‐free HIV infection (1998) (10)
- Particulate matter phagocytosis induces tissue factor in differentiating macrophages (2016) (10)
- International sensitivity index calibration of the near-patient testing prothrombin time monitor, ProTime. (2003) (10)
- The Genetic Defect of Type I von Willebrand Disease “Vicenza” Is Linked to the von Willebrand Factor Gene (1993) (10)
- Combined Use of DNA Probes in First-Trimester Prenatal Diagnosis of Hemophilia A (1987) (9)
- Lack of Correlation Between Activation of Hemostatic Mechanism and Inflammation in Unstable Angina Pectoris (1998) (9)
- Von Willebrand's Disease. (2017) (9)
- A Pilot Study of Pro-Urokinase in the Treatment of Deep Vein Thrombosis (1994) (9)
- Studies of multimerin in patients with von Willebrand disease and platelet von Willebrand factor deficiency (1998) (9)
- Venous thromboembolism and hormone replacement therapy. (2001) (9)
- Methods for the preparation of washed platelet suspensions. (1972) (9)
- Blood lead levels following consumption of game meat in Italy (2017) (9)
- Mechanism of hemostasis defects and management of bleeding in patients with acute coronary syndromes. (2010) (9)
- Desmopressin (DDAVP) and factor VIII: the tale as viewed from Milan (and Malmö) (2003) (9)
- Anti-LAV and Concentrate Consumption in Italian Hemophiliacs (1985) (9)
- Identification of four novel polymorphisms in the Aalpha and gamma fibrinogen genes and analysis of association with plasma levels of the protein. (2001) (9)
- Von Willebrand disease type 2N: An update (2021) (9)
- Choice of replacement therapy for hemophilia: recombinant products only? (2000) (9)
- Standardization of activated protein C resistance testing: effect of residual platelets in frozen plasmas assessed by commercial and home‐made methods (2003) (9)
- Airborne pollution and cardiovascular disease: burden and causes of an epidemic. (2013) (9)
- Effects of subcutaneously administered dermatan sulfate (MF 701) on the coagulation and fibrinolytic parameters of healthy volunteers. (1991) (9)
- Viral safety of coagulation factor concentrates. (1993) (9)
- Thrombophilia screening: little role for the JAK2V617F mutation. (2008) (9)
- Effect of Oral Aspirin on Plasma Levels of Vitamin K-Dependent Clotting Factors – Studies in Healthy Volunteers (1988) (9)
- Serum hepatitis B virus DNA detects cryptic hepatitis B virus infections in multitransfused hemophilic patients. (1990) (8)
- Pro-coagulant imbalance in patients with chronic liver disease. (2010) (8)
- Side effects of antihemophilic concentrates. (2009) (8)
- Dabigatran versus warfarin in patients with atrial fibrillation. (2009) (8)
- Aging with Hemophilia: The Challenge of Appropriate Drug Prescription (2019) (8)
- Psychological impact of thrombosis in the young (2006) (8)
- High-titre inhibitors in previously untreated patients with severe haemophilia A receiving recombinant or plasma-derived factor VIII: a budget-impact analysis. (2018) (8)
- Impact of the post‐COVID‐19 condition on health care after the first disease wave in Lombardy (2022) (8)
- Polymorphisms in the factor VII gene and the risk of myocardial infarction. (2001) (8)
- Prevalence of HTLV‐IIVLAV antibodies in Italian asymptomatic hemophiliacs given commercial concentrates of factors VIII and IX (1986) (8)
- B19 Parvovirus Withstands “Super Heating” in Antihemophilic Concentrates (1996) (8)
- Autoimmune hemophilia at rescue (2009) (8)
- Predictors of clinical events occurring during hospital stay among elderly patients admitted to medical wards in Italy. (2016) (8)
- The −308 G/A polymorphism in the tumor necrosis factor‐α gene is not associated with development and progression of rheumatoid arthritis in Argentinean patients (2016) (8)
- Views of medical practitioners about deprescribing in older adults: Findings from an Italian qualitative study. (2020) (8)
- Viral safety of plasma‐derived and recombinant products used in the management of haemophilia A and B (1995) (8)
- Models for institutional and professional accreditation of haemophilia centres in Italy (2013) (8)
- [HIV-related thrombocytopenias]. (2000) (8)
- Prophylaxis in congenital coagulation disorders: past, present and future. (2008) (8)
- The role of natural VWF/FVIII complex concentrates in contemporary haemophilia care: a guideline for the next decade (2012) (8)
- Treatment with stanazolol of type I protein C deficiency in an Italian family (1984) (8)
- Congenital deficiencies of anticoagulant proteins (antithrombin III and protein C). (1984) (8)
- Multicentre comparison of nine coagulometers and manual tilt-tube methods for prothrombin time performance. (1983) (8)
- Chromatographic and electrophoretic pattern of lactate and malate dehydrogenase in normal human adult and foetal muscle and in muscle of patients affected by Duchenne muscular dystrophy. (1966) (8)
- More on: are randomized clinical trials the only truth? Not always (2006) (8)
- Coagulation and platelet activation after retinal vein occlusions. (1982) (8)
- Fifth Åland Island conference on von Willebrand disease (2018) (8)
- Recombinant factor VIIa as haemostatic therapy in advanced liver disease. (2013) (7)
- Antipsychotic prescription and mortality in hospitalized older persons (2017) (7)
- Current status of non-transfusional haemostatic agents. (1999) (7)
- Characterization of an Abnormal Antithrombin (Milano 2) with Defective Thrombin Binding (1986) (7)
- Factor VII gene polymorphisms are not associated with myocardial infarction in young women (2005) (7)
- Consumption of clotting factors in severe haemophilia patients undergoing prophylaxis and on‐demand treatment in Italy (2011) (7)
- Immunogenicity of factor VIII concentrates in patients with hemophilia: a randomized clinical trial is warranted. (2007) (7)
- The response of plasma von Willebrand factor to desmopressin (DDAVP) is related to the platelet levels of von Willebrand factor. (1992) (7)
- Low risk of thrombosis in family members of patients with hyperhomocysteinaemia (2002) (7)
- Hypercoagulability in congenital haemolytic anaemias. (2012) (7)
- Risk of Venous Thromboembolism and Clinical Manifestations in Carriers of Antithrombin , Protein C , Protein S Deficiency , or Activated Protein C Resistance (1999) (7)
- Post-authorization pharmacovigilance for hemophilia in Europe and the USA: Independence and transparency are keys. (2021) (7)
- Hemostatic Functions in Hypoalpha and Hyperbetalipoproteinemias (1983) (7)
- Hemophilia: State of the Art of Hematologic Care 1988 (1989) (7)
- Assessing the risk of inhibitor formation with different factor VIII products. (2006) (7)
- Effect of cyclic AMP and related drugs on plasminogen activator (1973) (7)
- Aspects of the Clinical Management of Hereditary Thrombophilia: A Personal Perspective (2000) (7)
- National survey of human immunodeficiency virus infection in Italian hemophiliacs: 1983–1987 (1988) (7)
- Haemophilia in the 1990s: Report of a Joint Meeting of the World Health Organization and World Federation of Hemophilia (1991) (7)
- Familial overexpression of beta antithrombin caused by an Asn135Thr substitution. (1999) (7)
- Internal and geriatric medicine: an alliance for the challenges of the elderly. (2012) (7)
- A novel two base pair deletion in the factor V gene associated with severe factor V deficiency. (2000) (7)
- Thrombosis and bleeding disorders outside Western countries (2007) (7)
- von Willebrand factor: what is its role in the immune response in haemophilia? (2011) (7)
- Alpha(2)-macroglobulin levels are high in adult patients with congenital antithrombin deficiency. (2000) (7)
- Oral and Poster Presentations (2003) (7)
- The P303T mutation in the human factor VII (FVII) gene alters the conformational state of the enzyme and causes a severe functional deficiency (2004) (7)
- Involvement of the IgE‐basophil system and mild complement activation in haemophilia B with anti‐factor IX neutralizing antibodies and anaphylaxis (2017) (7)
- Viral safety of coagulation factor concentrates: memoirs from an insider (2018) (7)
- Panel discussion on the treatment of patients with factor VIII inhibitors. (1984) (7)
- Defensive medicine: Everything and its opposite. (2020) (7)
- Electrophoretic characterization of glutamic oxalacetic transaminase in human red cells of different ages. (1966) (7)
- Inherited deficiency of antithrombin III in an Italian kindred (1980) (7)
- Sustainable and personalized nutrition: From earth health to public health. (2021) (7)
- Pharmacist-driven medication recognition/ reconciliation in older medical patients. (2020) (7)
- Simulation-based education for physicians to increase oral anticoagulants in hospitalized elderly patients with atrial fibrillation. (2019) (7)
- In vivo experiments indicate that relatively high platelet deposition in von Willebrand's disease 'Vicenza' is caused by normal platelet-VWF levels rather than by high VWF-multimers in plasma. (1992) (6)
- Elevation of thrombin-antithrombin complexes during thrombolytic therapy in patients with myocardial infarction (1990) (6)
- Kaposi's sarcoma without human immunodeficiency virus antibody in a hemophiliac. (1986) (6)
- Assessment of a new instrument (Coag-A-Mate X2) for performing global clotting tests and specific factor assays. (1985) (6)
- Overview of Bleeding in Cancer Patients (2003) (6)
- Coagulation and Blood Transfusion (1991) (6)
- High-purity factor VIII concentrates produced without using monoclonal antibodies (1990) (6)
- Predictive value of coagulation tests in arterial thrombosis (1988) (6)
- The increased demand for plasma-derived factor VIII in Italy. (2017) (6)
- Hyperprothrombinemia may result in scquired activated protein C reistance. (2000) (6)
- Identification of three candidate mutations causing type IIA von Willebrand disease using a rapid, nonradioactive, allele-specific hybridization method. (1993) (6)
- The demand for factor VIII and for factor IX and the toll fractionation product surplus management. (2013) (6)
- Transfusion Requirements Are Correlated with the Degree of Proteolysis of von Willebrand Factor during Orthotopic Liver Transplantation (1997) (6)
- Appropriateness of prescription of oral anticoagulant therapy in acutely hospitalized older people with atrial fibrillation. Secondary analysis of the SIM‐AF cluster randomized clinical trial (2019) (6)
- Efficacy and safety of a recombinant factor VIII produced from a human cell line (simoctocog alfa) (2017) (6)
- von Willebrand factor: a prima ballerina on two different stages. (2005) (6)
- Plasma-derived medicinal products: demand and clinical use. (2013) (6)
- CIRCULATING ANTICOAGULANTS IN HÆMOPHILIA (1970) (6)
- Rate and appropriateness of polypharmacy in older patients with hemophilia compared with age‐matched controls (2018) (6)
- More on: enhanced thrombin generation in patients with cirrhosis‐induced coagulopathy (2011) (6)
- Clinical manifestations and complications of childbirth and replacement therapy in 385 Iranian patients with type 3 von Willebrand disease (2000) (6)
- Need for Deprescribing in Hospital Elderly Patients Discharged with a Limited Life Expectancy: The REPOSI Study (2019) (6)
- Sharing data of clinical trials. (2016) (6)
- CLOTTING FACTORS IN VON WILLEBRAND'S DISEASE (1974) (6)
- Von Willebrand's syndrome. (1979) (6)
- Recommendations for factor VIII product source to treat patients with haemophilia A. (2017) (6)
- Recombinant Human Von Willebrand Factor (rhVWF): First-In-Human Study Evaluating Pharmacokinetics, Demonstrating Safety and Tolerability In Type 3 Von Willebrand Disease (2010) (5)
- Report on the workshop: Von Willebrand factor and thrombotic thrombocytopenic purpura (2001) (5)
- Effect of prothrombin 19911 A>G polymorphism on the risk of cerebral sinus‐venous thrombosis (2010) (5)
- Protective effect of prophylaxis on inhibitor development in children with haemophilia A: more convincing studies are required. Response to Calvez and Laurian (2006) (5)
- Immunoradiometric Assay of Factor VIII Related Antigen (1975) (5)
- Very Low Frequency of “Normandy Type” Mutations among Type 1 von Willebrand Disease Families (1995) (5)
- Direct oral anticoagulants and cirrhosis: More evidence still needed for efficacy and safety in portal vein thrombosis. (2019) (5)
- Incidence of low‐titre factor VIII inhibitors in patients with haemophilia A: meta‐analysis of observational studies (2017) (5)
- A randomized, placebo-controlled, blind anti-AIDS clinical trial: safety and immunogenicity of a specific anti-IFN alpha immunization. (1994) (5)
- Prophylactic management of patients with von Willebrand disease (2021) (5)
- Clinical factors associated with death in 3044 COVID-19 patients managed in internal medicine wards in Italy: comment (2021) (5)
- Coexistence of haemophilia A and von Willebrand's disease in the same kindred. (2009) (5)
- Dissociated antibody responses to the s and pre‐s2 regions of the hepatitis b virus after vaccination in hemophiliacs (1989) (5)
- Hemophilia [4] (multiple letters) (2001) (5)
- Randomized double-blind, placebo-controlled trial of twice-daily zidovudine in asymptomatic haemophiliacs infected with the human immunodeficiency virus type 1. European-Australian Haemophilia Collaborative Study Group. (1994) (5)
- Thromboxane generation by human monocytes enhances platelet function (1986) (5)
- Multiple gene interaction and modulation of hemostatic balance (2009) (5)
- Continuous infusion of porcine factor VIII: stability, microbiological safety and clinical experience (2002) (5)
- The international normalized ratio to prioritize patients for liver transplantation: problems and possible solutions (2008) (5)
- Changing epidemiology of the hemolytic uremic syndrome and thrombotic thrombocytopenic purpura in southern Iran (2006) (5)
- Treatment of Hemophilia - More Amazing Progress. (2020) (5)
- Characterization of a partial deletion of the factor VIII gene in a haemophiliac with inhibitor (1988) (5)
- c.301C>T (p.Arg101Cys): A novel mutation in the thrombin-sensitive region of protein S associated with a dysfunctional protein (2006) (5)
- Hospital Care of Older Patients With COPD: Adherence to International Guidelines for Use of Inhaled Bronchodilators and Corticosteroids. (2019) (5)
- Erratum: Glazmann thrombasthenia and Bernard Soulier syndrome in South Iran (Clinical and Laboratory Haematology (2005) 27, (324-327)) (2006) (5)
- Intelligent game engines for home exercises (exergames) in boys with haemophilia (2020) (5)
- High levels of circulating von Willebrand factor inhibit the release of this protein but not of plasminogen activator after DDAVP. (1985) (5)
- Supranormal antithrombin III levels induced by concentrate administration are ineffective in quenching thrombin generation in acute promyelocytic leukemia. (1993) (5)
- Factor VIII inhibitors in previously treated hemophilic patients (2011) (5)
- Carrier detection in factor VII congenital deficiency (1985) (5)
- Traffic-related air pollution and the coronavirus pandemia: shadows and lights (2020) (5)
- The importance of ABO blood group in pharmacokinetic studies in haemophilia A (2018) (5)
- Abstract 4011: Influence Of Rs1333040, A Newly Discovered 9p21.3 Genetic Variant, On Clinical Outcomes In Early-onset Myocardial Infarction (2008) (5)
- Management of Hemophilia in Older Patients (2017) (5)
- Inhibitor development, immune tolerance and prophylaxis in haemophilia A – the need for an evidence‐based approach (2006) (5)
- Hemorrhagic telangiectasia and hemophilia A: an occasional association? (1983) (4)
- Thrombolytic therapy of acute deep vein thrombosis of the lower limbs: Choices, indications and limits (1984) (4)
- Recombinant porcine factor VIII: a new instalment of a long story (2015) (4)
- PCR analysis of HIV‐1 sequences and differential immunological features in seronegative and seropositive haemophiliacs (1992) (4)
- Emerging drugs for hemophilia B (2014) (4)
- Immunogenicity of a yeast‐recombinant hepatitis B vaccine in high‐risk children (1989) (4)
- β-thromboglobulin and fibrinopeptide a in diabetes mellitus as markers of vascular damage (2007) (4)
- Impact of Diabetes Mellitus and Its Comorbidities on Elderly Patients Hospitalized in Internal Medicine Wards: Data from the RePoSi Registry (2022) (4)
- Vagaries of genetic association studies in myocardial infarction. (2003) (4)
- A Randomized, Double-Blind, Placebo-Controlled, Clinical Outcome Study of ARC1779 In Patients with Thrombotic Thrombocytopenic Purpura (TTP) (2010) (4)
- Treatment of von Willebrand disease (1998) (4)
- Genome-Wide Association Studies in Myocardial Infarction and Coronary Artery Disease (2010) (4)
- Initiation of Psycholeptic Medication During Hospitalization With Recommendation for Discontinuation After Discharge. (2020) (4)
- CHARACTERISTICS OF LACTIC DEHYDROGENASES IN HUMAN ERYTHROCYTES. (1964) (4)
- Thrombotic microangiopathies: the past as prologue. (2013) (4)
- Chlorpropamide-alcohol flushing in non insulin-dependent diabetes: Prevalence of small and large vessel disease and of risk factors for angiopathy (1982) (4)
- Therapeutic Duplicates in a Cohort of Hospitalized Elderly Patients: Results from the REPOSI Study (2016) (4)
- Bleeding symptoms in heterozygous factor VIII deficiency (2010) (4)
- Predictors of inhibitor eradication by primary immune tolerance induction in severe haemophilia A with high responding inhibitors (2021) (4)
- Prognostic relevance of glomerular filtration rate estimation obtained through different equations in hospitalized elderly patients. (2018) (4)
- Cardiovascular health and ambient air pollution: lower is not enough. (2020) (4)
- Subunit Composition of Plasma von Willebrand Factor (vWF) in Two Uremic Patients with Acquired vWF Abnormalities (1992) (4)
- Polypharmacy in older adults with severe haemophilia (2018) (4)
- New anticoagulants in internal medicine: an update. (2010) (4)
- Integrated care: easy in theory, harder in practice? (2021) (4)
- Activation of the Protein C Pathway in Hereditary Thrombophilia (1998) (4)
- Comparison between drug therapy-based comorbidity indices and the Charlson Comorbidity Index for the detection of severe multimorbidity in older subjects (2020) (4)
- PROTHROMBIN-COMPLEX CONCENTRATES IN LIVER DISEASE (1975) (4)
- Use of Lipid-Lowering Drugs and Associated Outcomes According to Health State Profiles in Hospitalized Older Patients (2021) (4)
- Thrombotic Thromboytopenic Purpura: Another Example of Immunomediated Thrombosis (2006) (4)
- The methodology for defining the European standards for the certification of Haemophilia Centres in Europe. (2014) (4)
- Ischemic stroke in congenital (type II C) defective antithrombin III (1993) (4)
- Genetic testing in von Willebrand disease: a rebuttal (2010) (4)
- Solicited self‐referencing undermines the credibility of researchers and journals (2012) (4)
- Polycythaemia vera and JAK2 mutation (2007) (4)
- Inflammatory bowel disease are not associated with the major hereditary conditions predisposing to thrombosis (1998) (4)
- Methods for the detection of activated platelets. (1984) (4)
- Screening of thrombophilia in women with failure of embryo implantation: far from being recommended. (2003) (4)
- Reply to: The importance and challenge of pediatric trials of hemophilia drugs (2014) (4)
- Hyperglycemia at admission, comorbidities, and in-hospital mortality in elderly patients hospitalized in internal medicine wards: data from the RePoSI Registry (2021) (4)
- PATHOGENESIS OF VON WILLEBRAND'S DISEASE (1976) (4)
- Hemophilia Care in Italy (1976) (4)
- Hyperglycemia at admission, comorbidities, and in-hospital mortality in elderly patients hospitalized in internal medicine wards: data from the RePoSI Registry (2021) (4)
- Interference of factor V Leiden on protein S activity: evaluation of a new prothrombin time-based assay (2007) (4)
- Pseudopathologies of hemostasis and dental surgery. (1991) (4)
- 282 HIGH INCIDENCE OF HEPARIN INDUCED THROMBOCYTOPENIA (HIT) IN SPLANCHNIC VEIN THROMBOSIS TREATED WITH LOW MOLECULAR WEIGHT HEPARIN (LMWH) (2008) (4)
- The More Recent History of Hemophilia Treatment. (2022) (4)
- Fibrin(ogen) Peptides in Early Breast Cancer (1989) (4)
- International survey of attitudes towards secondary prophylaxis with recombinant factor VIIa in haemophilia A patients with inhibitors (2009) (3)
- Clinical and laboratory observations in eight patients with lupus-type circulating anticoagulant. (1979) (3)
- Varied immunological reactivity of factor VIII from animal plasmas. (1980) (3)
- Vaccine-induced immune thrombotic thrombocytopenia with atypical vein thrombosis: Implications for clinical practice (2022) (3)
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- Biological Responses to Repeated Doses of Desmopressin (DDAVP) in Patients with Hemophilia and Von Wille Brand’s Disease (1993) (0)
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- CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS The Incidence of Venous Thromboembolism in Asymptomatic Carriers of a Deficiency of Antithrombin, Protein C, or Protein S: A Prospective Cohort Study (2016) (0)
- [Defibrination syndrome: treatment with an antifibrinolytic drug and anticoagulants]. (1967) (0)
- Questions and Answers (Workshop III) (1981) (0)
- Contents Vol. 32, 2002 (2002) (0)
- Over-expression of beta antithrombin in familial antithrombin deficiency caused by an ASN135 to THR mutation (1997) (0)
- [The Annals, which way does it go: the last two years (1996-1997)]. (1998) (0)
- Molecular Mapping of the Chloride Binding Site in von Willebrand Factor (VWF): Energetics and Conformational Effects on the ADAMTS-13 Interaction with Wild Type and Type 2B R1306W VWF Forms. (2006) (0)
- Prognostic value of coagulation parameters in liver transplantation (1990) (0)
- 9th BIC International Conference: Rome (Italy), 15-17 September 2017. (2017) (0)
- Effectiveness of a Heated Prothrombin Complex Concentrate in Hemophiliacs with Inhibitors (1987) (0)
- [6 years with Annali Italiani di Medicina Interna]. (2000) (0)
- Protein C,An Inhibitor of Blood Coagulation, in Liver Disease and other Clinical Conditions (1984) (0)
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