Pierangelo Geppetti
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Philosophy Biology
Pierangelo Geppetti's Degrees
- PhD Neuroscience University of Florence
- Doctorate Medicine University of Florence
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(Suggest an Edit or Addition)Pierangelo Geppetti's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors (2002) (981)
- Nitric oxide mediates angiogenesis in vivo and endothelial cell growth and migration in vitro promoted by substance P. (1994) (865)
- 4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1 (2007) (703)
- Mast cell-dependent excitation of visceral-nociceptive sensory neurons in irritable bowel syndrome. (2007) (674)
- Tachykinins and their receptors: contributions to physiological control and the mechanisms of disease. (2014) (423)
- Protease-Activated Receptor 2 Sensitizes the Capsaicin Receptor Transient Receptor Potential Vanilloid Receptor 1 to Induce Hyperalgesia (2004) (400)
- Protease‐activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice (2007) (363)
- Cigarette smoke-induced neurogenic inflammation is mediated by alpha,beta-unsaturated aldehydes and the TRPA1 receptor in rodents. (2008) (347)
- Protons: small stimulants of capsaicin-sensitive sensory nerves (1994) (313)
- The TGR5 receptor mediates bile acid-induced itch and analgesia. (2013) (290)
- Oxaliplatin elicits mechanical and cold allodynia in rodents via TRPA1 receptor stimulation (2011) (272)
- Substance P stimulates neovascularization in vivo and proliferation of cultured endothelial cells. (1990) (266)
- Increase in plasma calcitonin gene-related peptide from the extracerebral circulation during nitroglycerin-induced cluster headache attack (1995) (259)
- Reduced Cardiocirculatory Complications With Unrestrictive Visiting Policy in an Intensive Care Unit: Results From a Pilot, Randomized Trial (2006) (256)
- The concept of neurogenic inflammation (2008) (227)
- Protease-Activated Receptor 2 Mediates Eosinophil Infiltration and Hyperreactivity in Allergic Inflammation of the Airway1 (2002) (225)
- The vanilloid receptor (VR1)‐mediated effects of anandamide are potently enhanced by the cAMP‐dependent protein kinase (2001) (212)
- Transient Receptor Potential Ankyrin 1 Channel Localized to Non-Neuronal Airway Cells Promotes Non-Neurogenic Inflammation (2012) (203)
- Activation and sensitisation of the vanilloid receptor: role in gastrointestinal inflammation and function (2004) (199)
- TRPA1 and TRPV4 mediate paclitaxel-induced peripheral neuropathy in mice via a glutathione-sensitive mechanism (2012) (193)
- Anandamide Excites Central Terminals of Dorsal Root Ganglion Neurons via Vanilloid Receptor-1 Activation (2001) (193)
- The transient receptor potential vanilloid 1: role in airway inflammation and disease. (2006) (190)
- Neutral endopeptidase (EC 3.4.24.11) terminates colitis by degrading substance P. (1999) (180)
- The bile acid receptor TGR5 activates the TRPA1 channel to induce itch in mice. (2014) (179)
- Alpha,beta-unsaturated aldehydes in cigarette smoke release inflammatory mediators from human macrophages. (2007) (176)
- Sensory neuropeptide release by bradykinin: mechanisms and pathophysiological implications (1993) (176)
- CGRP receptors in the control of pain and inflammation. (2009) (170)
- TRPV1: a therapeutic target for novel analgesic drugs? (2006) (170)
- The 'headache tree' via umbellulone and TRPA1 activates the trigeminovascular system. (2012) (169)
- Hydrogen sulfide causes vanilloid receptor 1‐mediated neurogenic inflammation in the airways (2005) (165)
- Noninvasive vagus nerve stimulation as acute therapy for migraine (2018) (165)
- Treatment with β-blockers and reduced disease progression in patients with thick melanoma. (2011) (164)
- The control of microvascular permeability and blood pressure by neutral endopeptidase (1997) (159)
- Cox-dependent fatty acid metabolites cause pain through activation of the irritant receptor TRPA1 (2008) (155)
- Randomised double-blind placebo-controlled study of the effect of inhibition of nitric oxide synthesis in bradykinin-induced asthma (1996) (153)
- The TRPA1 channel in inflammatory and neuropathic pain and migraine. (2014) (151)
- Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents. (2010) (151)
- Effect of an NK1 receptor antagonist (CP-99,994) on hypertonic saline-induced bronchoconstriction and cough in male asthmatic subjects. (1995) (140)
- Novel therapeutic strategy to prevent chemotherapy-induced persistent sensory neuropathy by TRPA1 blockade. (2013) (136)
- Schwann cell TRPA1 mediates neuroinflammation that sustains macrophage-dependent neuropathic pain in mice (2017) (134)
- Nitric oxide promotes DNA synthesis and cyclic GMP formation in endothelial cells from postcapillary venules. (1993) (133)
- Propranolol for Off-label Treatment of Patients With Melanoma: Results From a Cohort Study (2017) (132)
- Secretion, pain and sneezing induced by the application of capsaicin to the nasal mucosa in man (1988) (129)
- Bronchoconstriction induced by citric acid inhalation in guinea pigs: role of tachykinins, bradykinin, and nitric oxide. (1999) (125)
- Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief (2017) (125)
- TRPA1 mediates trigeminal neuropathic pain in mice downstream of monocytes/macrophages and oxidative stress. (2016) (124)
- Distribution of calcitonin gene-related peptide-like immunoreactivity in various rat tissues: correlation with substance P and other tachykinins and sensitivity to capsaicin (1988) (121)
- The TRPA1 channel in migraine mechanism and treatment (2014) (118)
- Acetaminophen, via its reactive metabolite N-acetyl-p-benzo-quinoneimine and transient receptor potential ankyrin-1 stimulation, causes neurogenic inflammation in the airways and other tissues in rodents. (2010) (117)
- Low pH-induced release of calcitonin gene-related peptide from capsaicin-sensitive sensory nerves: Mechanism of action and biological response (1991) (115)
- Antitussive activity of iodo-resiniferatoxin in guinea pigs (2004) (115)
- Expression of capsaicin receptor immunoreactivity in human peripheral nervous system and in painful neuropathies (2006) (114)
- Calcitonin gene-related peptide as inflammatory mediator. (2003) (114)
- Predictive Validity of Measures of Comorbidity in Older Community Dwellers: The Insufficienza Cardiaca negli Anziani Residenti a Dicomano Study (2006) (111)
- Activation of TRPA1 on dural afferents: A potential mechanism of headache pain (2012) (110)
- Acute ACE inhibition causes plasma extravasation in mice that is mediated by bradykinin and substance P. (1998) (110)
- Endosomal signaling of the receptor for calcitonin gene-related peptide mediates pain transmission (2017) (110)
- Pain relief by somatostatin in attacks of cluster headache (1984) (109)
- The antagonism induced by ruthenium red of the actions of capsaicin on the peripheral terminals of sensory neurons: further studies. (1988) (107)
- G Protein-Coupled Receptors: Dynamic Machines for Signaling Pain and Itch (2015) (106)
- Critical role of calcitonin gene-related peptide receptors in cortical spreading depression (2012) (104)
- Adherence to antihypertensive medications and health outcomes among newly treated hypertensive patients (2011) (103)
- NK1 receptors mediate leukocyte adhesion in neurogenic inflammation in the rat trachea. (1995) (102)
- What is the evidence for the role of TRP channels in inflammatory and immune cells? (2015) (102)
- Beneficial Effect of Capsaicin Application to the Nasal Mucosa in Cluster Headache (1989) (96)
- Neurogenic responses mediated by vanilloid receptor‐1 (TRPV1) are blocked by the high affinity antagonist, iodo‐resiniferatoxin (2003) (94)
- Ethanol Causes Neurogenic Vasodilation by TRPV1 Activation and CGRP Release in the Trigeminovascular System of The Guinea Pig (2008) (94)
- TRPA1 receptor stimulation by hydrogen peroxide is critical to trigger hyperalgesia and inflammation in a model of acute gout. (2014) (93)
- Substance P and bradykinin stimulate plasma extravasation in the mouse gastrointestinal tract and pancreas. (1997) (93)
- Differential effect on neuropeptide release of different concentrations of hydrogen ions on afferent and intrinsic neurons of the rat stomach. (1991) (92)
- Simultaneous release by bradykinin of substance P‐and calcitonin gene‐related peptide immunoreactivities from capsaicin‐sensitive structures in guinea‐pig heart (1988) (92)
- Substance p. (2001) (91)
- Allergen-induced impairment of bronchoprotective nitric oxide synthesis in asthma. (2001) (91)
- Adherence to statin treatment and health outcomes in an Italian cohort of newly treated patients: results from an administrative database analysis. (2012) (89)
- Release of calcitonin gene-related peptide like-immunoreactivity induced by electrical field stimulation from rat spinal afferents is mediated by conotoxin-sensitive calcium channels (1992) (89)
- Parthenolide inhibits nociception and neurogenic vasodilatation in the trigeminovascular system by targeting the TRPA1 channel (2013) (88)
- Ethanol Causes Inflammation in the Airways by a Neurogenic and TRPV1-Dependent Mechanism (2004) (88)
- Substance P released by TRPV1-expressing neurons produces reactive oxygen species that mediate ethanol-induced gastric injury. (2007) (87)
- Role of neurogenic inflammation in antigen-induced vascular extravasation in guinea pig trachea. (1993) (86)
- TRPA1/NOX in the soma of trigeminal ganglion neurons mediates migraine-related pain of glyceryl trinitrate in mice (2018) (86)
- Tachykinin and kinin receptor antagonists: therapeutic perspectives in allergic airway disease. (1996) (86)
- SARS-CoV-2 and COVID-19: From the Bench to the Bedside (2020) (85)
- Protease-Activated Receptor-2 Stimulates Angiogenesis and Accelerates Hemodynamic Recovery in a Mouse Model of Hindlimb Ischemia (2002) (85)
- Novel therapeutic targets (2006) (85)
- Cough: The Emerging Role of the TRPA1 Channel (2009) (83)
- Cough · 5: The type 1 vanilloid receptor: a sensory receptor for cough (2004) (83)
- CGRP and migraine: neurogenic inflammation revisited (2005) (83)
- Hydrogen sulfide inhibits human platelet aggregation. (2007) (80)
- The 'efferent' function of capsaicin-sensitive nerves: ruthenium red discriminates between different mechanisms of activation. (1989) (80)
- Mediators of asthma: nitric oxide. (2002) (79)
- Evidence for differential expression of Notch receptors and their ligands in melanocytic nevi and cutaneous malignant melanoma (2006) (78)
- Preventative effect of repeated nasal applications of capsaicin in cluster headache (1994) (77)
- Protective action of Ruthenium red toward capsaicin desensitization of sensory fibers (1988) (76)
- The effect of calcium free medium and nifedipine on the release of substance P-like immunoreactivity and contractions induced by capsaicin in the isolated guinea-pig and rat bladder. (1989) (76)
- Evidence that epithelium-derived relaxing factor released by bradykinin in the guinea pig trachea is nitric oxide. (1996) (76)
- The contribution of capsaicin-sensitive innervation to activation of the spinal vesico-vesical reflex in rats: relationship between substance P levels in the urinary bladder and the sensory-efferent function of capsaicin-sensitive sensory neurons (1987) (73)
- Botulinum Toxin type A reduces capsaicin-evoked pain and neurogenic vasodilatation in human skin (2007) (73)
- Expression of protease-activated receptors 1 and 2 in melanocytic nevi and malignant melanoma. (2005) (73)
- Development of the First Ultra-Potent “Capsaicinoid” Agonist at Transient Receptor Potential Vanilloid Type 1 (TRPV1) Channels and Its Therapeutic Potential (2005) (72)
- Protease-activated receptor-2 activation exaggerates TRPV1-mediated cough in guinea pigs. (2006) (72)
- Substance P and endogenous opioids: how and where they could play a role in cluster headache (1983) (71)
- Topical versus systemic capsaicin desensitization: Specific and unspecific effects as indicated by modification or reflex micturition in rats (1989) (71)
- A comparison of bradykinin‐ and capsaicin‐induced myocardial and coronary effects in isolated perfused heart of guinea‐pig: involvement of substance P and calcitonin gene‐related peptide release (1989) (70)
- Impairment of bronchoprotection by nitric oxide in severe asthma (1997) (69)
- TRPA1 and other TRP channels in migraine (2013) (69)
- Regional differences in the motor response to capsaicin in the guinea-pig urinary bladder: Relative role of pre- and postjunctional factors related to neuropeptide-containing sensory nerves (1988) (67)
- Transient receptor potential ankyrin 1 receptor stimulation by hydrogen peroxide is critical to trigger pain during monosodium urate-induced inflammation in rodents. (2013) (66)
- Effect of β-blockers and other antihypertensive drugs on the risk of melanoma recurrence and death. (2013) (66)
- Capsaicin desensitization protects from antigen-induced bronchospasm in conscious guinea-pigs. (1987) (64)
- Capsaicin increases airflow resistance in guinea pigs in vivo by activating both NK2 and NK1 tachykinin receptors. (1993) (64)
- The TRPA1 channel mediates the analgesic action of dipyrone and pyrazolone derivatives (2015) (63)
- Role of kinins in the vascular extravasation evoked by antigen and mediated by tachykinins in guinea pig trachea. (1993) (63)
- Involvement of neurogenic inflammation in antigen-induced bronchoconstriction in guinea pigs. (1993) (62)
- Pungent General Anesthetics Activate Transient Receptor Potential-A1 to Produce Hyperalgesia and Neurogenic Bronchoconstriction (2010) (62)
- The peptide Phα1β, from spider venom, acts as a TRPA1 channel antagonist with antinociceptive effects in mice (2017) (61)
- Halogenation of a capsaicin analogue leads to novel vanilloid TRPV1 receptor antagonists (2003) (60)
- TRPA1 as a therapeutic target for nociceptive pain (2020) (59)
- Arachidonic acid and bradykinin share a common pathway to release neuropeptide from capsaicin-sensitive sensory nerve fibers of the guinea pig heart. (1991) (58)
- Bradykinin-induced release of calcitonin gene-related peptide from capsaicin-sensitive nerves in guinea-pig atria: Mechanism of action and calcium requirements (1990) (57)
- Release of calcitonin gene-related peptide-like immunoreactivity (CGRP-LI) from organs of the genitourinary tract in rats (1988) (57)
- Substance P induces migration of capillary endothelial cells: a novel NK-1 selective receptor mediated activity. (1991) (56)
- Evidence for reduction of bradykinin‐induced bronchoconstriction in guinea‐pigs by release of nitric oxide (1994) (55)
- Substance P-like immunoreactivity in capsaicin-sensitive structures of the rat thymus (1987) (55)
- Steroidal and non-steroidal third-generation aromatase inhibitors induce pain-like symptoms via TRPA1 (2014) (55)
- The influence of alpha1-adrenoreceptors on neuropeptide release from primary sensory neurons of the lower urinary tract. (2007) (54)
- Multiple mechanisms in the motor responses of the guinea‐pig isolated urinary bladder to bradykinin (1989) (54)
- Antidromic vasodilatation and the migraine mechanism (2011) (53)
- The contribution of sensory nerves to xylene-induced cystitis in rats (1988) (53)
- Tachykinin-like immunoreactivity in the mammalian urinary bladder: Correlation with the functions of the capsaicin-sensitive sensory nerves (1988) (50)
- Protease-activated receptor 1-selective antagonist SCH79797 inhibits cell proliferation and induces apoptosis by a protease-activated receptor 1-independent mechanism. (2007) (50)
- Cutaneous lesions in capsaicin-pretreated rats. A trophic role of capsaicin-sensitive afferents? (1987) (49)
- Release of sensory neuropeptides from dural venous sinuses of guinea pig (1990) (49)
- Plasma extravasation in the rat trachea induced by cold air is mediated by tachykinin release from sensory nerves. (1995) (49)
- Tachykinins in the respiratory tract. (2006) (49)
- Substance P Theory: A Unique Focus on the Painful and Painless Phenomena of Cluster Headache (1990) (49)
- Pharmacological assessment of the duration of action of glycopyrrolate vs tiotropium and ipratropium in guinea‐pig and human airways (2006) (48)
- Role of kinins in anaphylactic‐induced bronchoconstriction mediated by tachykinins in guinea‐pigs (1994) (46)
- Substance P and Somatostatin Levels in Rheumatoid Arthritis, Osteoarthritis, and Psoriatic Arthritis Synovial Fluid (1991) (45)
- Neurochemical evidence for the activation of the ‘efferent’ function of capsaicin-sensitive nerves by lowering of the pH in the guinea-pig urinary bladder (1990) (45)
- Capsaicin-like effects of N-arachidonoyl-dopamine in the isolated guinea pig bronchi and urinary bladder. (2003) (44)
- Ethanol dilates coronary arteries and increases coronary flow via transient receptor potential vanilloid 1 and calcitonin gene-related peptide. (2006) (44)
- Simultaneous release of substance P- and calcitonin gene-related peptide (CGRP)-like immunoreactivity from isolated muscle of the guinea pig urinary bladder (1988) (43)
- Transient receptor potential channels as novel drug targets in respiratory diseases. (2010) (42)
- Is TRPV1 a useful target in respiratory diseases? (2008) (42)
- Substance P Mechanism in Cluster Headache: Evaluation in Plasma and Cerebrospinal Fluid (1985) (42)
- Schwann cells expressing nociceptive channel TRPA1 orchestrate ethanol-evoked neuropathic pain in mice. (2019) (42)
- Epidemiology of Suboptimal Prescribing in Older, Community Dwellers (2009) (41)
- In vivo 'enkephalinase' inhibition by acetorphan in human plasma and CSF. (1986) (41)
- Different pathways by which extracellular Ca2+ promotes calcitonin gene-related peptide release from central terminals of capsaicin-sensitive afferents of guinea pigs: effect of capsaicin, high K+ and low pH media (1991) (41)
- Genome-wide association study of serious blistering skin rash caused by drugs (2011) (41)
- Neuropeptide Release from Sensory Fibres of Guinea Pig Cerebral Venous Sinuses and Dorsal Spinal Cord: Relevance for Headache Study (1989) (40)
- Release of calcitonin gene-related peptide-like (CGRP-LI) immunoreactivity from rat isolated soleus muscle by low pH, capsaicin and potassium (1992) (40)
- Release of VIP- but not CGRP-like immunoreactivity by capsaicin from the human isolated small intestine (1989) (39)
- The blockade of transient receptor potential ankirin 1 (TRPA1) signalling mediates antidepressant‐ and anxiolytic‐like actions in mice (2014) (39)
- Investigating the Effects of COVID-19 Quarantine in Migraine: An Observational Cross-Sectional Study From the Italian National Headache Registry (RICe) (2020) (39)
- Cold air-induced bronchoconstriction is mediated by tachykinin and kinin release in guinea pigs. (1996) (39)
- Endogenous nitric oxide inhibits bronchoconstriction induced by cold-air inhalation in guinea pigs: role of kinins. (1998) (39)
- Cough • 7: Current and future drugs for the treatment of chronic cough (2004) (39)
- Prostate growth and prevalence of prostate diseases in early onset spinal cord injuries. (2009) (39)
- Pharmacological characterisation of the plant sesquiterpenes polygodial and drimanial as vanilloid receptor agonists. (2006) (38)
- Pleasant natural scent with unpleasant effects: Cluster headache-like attacks triggered by Umbellularia californica (2010) (38)
- Involvement of a peripheral site of action in the early phase of neuropeptide depletion following capsaicin desensitization (1987) (38)
- Evidence that tachykinins relax the guinea‐pig trachea via nitric oxide release and by stimulation of a septide‐insensitive NK1 receptor (1996) (38)
- β3‐Adrenoceptor as a potential immuno‐suppressor agent in melanoma (2019) (37)
- Evidence that toluene diisocyanate activates the efferent function of capsaicin-sensitive primary afferents. (1990) (37)
- The anti‐migraine component of butterbur extracts, isopetasin, desensitizes peptidergic nociceptors by acting on TRPA1 cation channel (2017) (37)
- The effect of omega conotoxin GVIA, a peptide modulator of the N-type voltage sensitive calcium channels, on motor responses produced by activation of efferent and sensory nerves in mammalian smooth muscle (1988) (37)
- Human papillomavirus and non-muscle invasive urothelial bladder cancer: potential relationship from a pilot study. (2011) (36)
- Poor patient awareness and frequent misdiagnosis of migraine: findings from a large transcontinental cohort (2019) (36)
- Proteinase-Activated Receptor-2 Mediates Arterial Vasodilation in Diabetes (2005) (36)
- Effects of alpha calcitonin gene-related peptide in human bronchial smooth muscle and pulmonary artery (2004) (36)
- Pain pharmacology in migraine: focus on CGRP and CGRP receptors (2007) (35)
- Altered pharmacology in the intensive care unit patient (2008) (34)
- NK1 receptor antagonist CP-99,994 inhibits cigarette smoke-induced neutrophil and eosinophil adhesion in rat tracheal venules. (1996) (34)
- A bicarbonate-alkaline mineral water protects from ethanol-induced hemorrhagic gastric lesions in mice. (2010) (34)
- Migraine-provoking substances evoke periorbital allodynia in mice (2019) (34)
- Transient receptor potential ankyrin 1 (TRPA1) plays a critical role in a mouse model of cancer pain (2018) (34)
- SARS-CoV-2 and COVID-19: between pathophysiology complexity and therapeutic uncertainty. (2020) (33)
- New aspects on the role of kinins in neurogenic inflammation. (1995) (33)
- Is suboptimal prescribing a risk factor for poor health outcomes in community‐dwelling elders? The ICARe Dicomano study (2010) (33)
- Increased liposome extravasation in selected tissues: effect of substance P. (1996) (32)
- Analysis of protease‐activated receptor‐1 and ‐2 in human scar formation (2007) (32)
- Capsaicin-desensitization to the human nasal mucosa selectively reduces pain evoked by citric acid. (1993) (32)
- Pain Treatment with Opioids (2009) (31)
- Capsaicin-induced release of neurokinin A from muscle and mucosa of gastric corpus: Correlation with capsaicin-evoked release of calcitonin gene-related peptide (1991) (31)
- Regional differences in the motor and inflammatory responses to capsaicin in guinea pig airways. Correlation with content and release of substance P-like immunoreactivity. (1989) (31)
- Tachykinins mediate contraction of the human lower esophageal sphincter in vitro via activation of NK2 receptors. (1993) (31)
- A new NK1 receptor antagonist (CP-99,994) prevents the increase in tracheal vascular permeability produced by hypertonic saline. (1993) (31)
- Acute oral captopril inhibits angiotensin converting enzyme activity in human cerebrospinal fluid. (1987) (31)
- Peptide N‐formyl‐methionyl‐leucyl‐phenylalanine (FMLP) activates capsaicin‐sensitive primary afferent nerves in guinea‐pig atria and urinary bladder (1991) (30)
- Plasma Changes of Calcitonin Gene-Related Peptide and Substance P in Patients with Dialysis Headache (2006) (30)
- Role of peptidases and NK1 receptors in vascular extravasation induced by bradykinin in rat nasal mucosa. (1993) (30)
- Capsaicin-sensitive tachykinin-like immunoreactivity in the thymus of rats and guinea-pigs (1988) (30)
- Involvement of tachykinins in plasma extravasation induced by bradykinin and low pH medium in the guinea‐pig conjunctiva (1995) (30)
- Biochemical, anatomical and functional correlates of postnatal development of the capsaicin-sensitive innervation of the rat urinary bladder. (1988) (30)
- Calcitonin gene-related peptide in the rat kidney: Occurrence, sensitivity to capsaicin, and stimulation of adenylate cyclase (1989) (30)
- TRP functions in the broncho-pulmonary system (2016) (30)
- Transient Receptor Potential Ankyrin 1 Channels Modulate Inflammatory Response in Respiratory Cells from Patients with Cystic Fibrosis. (2016) (30)
- Consistent effects of non-invasive vagus nerve stimulation (nVNS) for the acute treatment of migraine: additional findings from the randomized, sham-controlled, double-blind PRESTO trial (2018) (29)
- The correlation between sensory-efferent functions mediated by the capsaicin-sensitive neurons and substance P content of the rat urinary bladder (1987) (29)
- Tachykinins and kinins in antigen-evoked plasma extravasation in guinea-pig nasal mucosa. (1994) (29)
- Consistent effects of non-invasive vagus nerve stimulation (nVNS) for the acute treatment of migraine: additional findings from the randomized, sham-controlled, double-blind PRESTO trial (2018) (29)
- TRP channels. (2015) (29)
- Ketones and pain: unexplored role of hydroxyl carboxylic acid receptor type 2 in the pathophysiology of neuropathic pain (2018) (28)
- Transient receptor potential channels and occupational exposure (2014) (28)
- Bedside diagnostic laparoscopy to diagnose intraabdominal pathology in the intensive care unit (2009) (28)
- Onabotulinumtoxin A for the management of chronic migraine in current clinical practice: results of a survey of sixty-three Italian headache centers (2017) (28)
- Cigarette smoke – induced neurogenic inflammation is mediated by α , β-unsaturated aldehydes and the TRPA 1 receptor in rodents (2008) (28)
- The involvement of the TRPA1 receptor in a mouse model of sympathetically maintained neuropathic pain. (2015) (27)
- Effects of capsaicin and 5‐HT3 antagonists on 5‐hydroxytryptamine‐evoked release of calcitonin gene‐related peptide in the guinea‐pig heart (1993) (26)
- Dopamine type 2 receptor expression and function in rodent sensory neurons projecting to the airways. (2005) (26)
- 7-Substituted-pyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as antagonists of the transient receptor potential ankyrin 1 (TRPA1) channel: a promising approach for treating pain and inflammation. (2012) (26)
- Bronchodilator Activity of (3R)-3-[[[(3-fluorophenyl)[(3,4,5-trifluorophenyl)methyl]amino] carbonyl]oxy]-1-[2-oxo-2-(2-thienyl)ethyl]-1-azoniabicyclo[2.2.2]octane bromide (CHF5407), a Potent, Long-Acting, and Selective Muscarinic M3 Receptor Antagonist (2010) (26)
- A sensitive sandwich enzyme immunoassay for calcitonin gene-related peptide (CGRP): Characterization and application (1999) (25)
- Role of nitric oxide and septide‐insensitive NK1 receptors in bronchoconstriction induced by aerosolised neurokinin A in guinea‐pigs (2000) (25)
- Contribution of peripheral endothelin ETA and ETB receptors in neuropathic pain induced by spinal nerve ligation in rats (2010) (25)
- Ruthenium red, but not capsazepine reduces plasma extravasation by cigarette smoke in rat airways (1993) (25)
- Schwann cell endosome CGRP signals elicit periorbital mechanical allodynia in mice (2022) (25)
- β-Blocker use and reduced disease progression in patients with thick melanoma: 8 years of follow-up. (2017) (25)
- Evidence for differential expression of Notch receptors and their ligands in melanocytic nevi and cutaneous malignant melanoma (2006) (25)
- Optimizing the long-term management of chronic migraine with onabotulinumtoxinA in real life (2018) (25)
- Relative contribution of sympathetic and sensory nerves to thermal nociception and tissue trophism in rats (1993) (24)
- Protease-activated receptor 2 expression in trigeminal neurons innervating the rat nasal mucosa (2005) (24)
- Acrylamide-induced visceral neuropathy: Evidence for the involvement of capsaicin-sensitive nerves of the rat urinary bladder (1991) (24)
- The Role of TRPA1 in Skin Physiology and Pathology (2021) (24)
- The antimigraine butterbur ingredient, isopetasin, desensitises peptidergic nociceptors via the transient receptor potential ankyrin 1 channel (2017) (24)
- Mechanical irritation induces neurogenic inflammation in the rat urethra. (1991) (24)
- Sensory nerves, vascular endothelium and neurogenic relaxation of the guinea-pig isolated pulmonary artery (1990) (24)
- Pharmacologic and neurochemical evidence for the activation of capsaicin-sensitive sensory nerves by lipoxin A4 in guinea pig bronchus. (1992) (24)
- Buspirone, but not sumatriptan, induces miosis in humans: Relevance for a serotoninergic pupil control (1995) (23)
- Calcitonin Gene—Related Peptide in the Regulation of Urinary Tract Motility (1992) (23)
- Ion Channel Pharmacology for Pain Modulation. (2019) (23)
- TRPA 1 mediates trigeminal neuropathic pain in mice downstream of monocytes / macrophages and oxidative stress (2016) (23)
- The acyl‐glucuronide metabolite of ibuprofen has analgesic and anti‐inflammatory effects via the TRPA1 channel (2019) (23)
- Arachidonic acid‐induced bronchomotor responses are partially mediated by release of sensory neuropeptides from capsaicin‐sensitive structures (1989) (22)
- Neurochemical evidence of calcitonin gene-related peptide-like immunoreactivity (CGRP-LI) release from capsaicin-sensitive nerves in rat mesenteric arteries and veins. (1991) (22)
- Macrophages and Schwann cell TRPA1 mediate chronic allodynia in a mouse model of complex regional pain syndrome type I (2020) (22)
- Practical and clinical utility of non-invasive vagus nerve stimulation (nVNS) for the acute treatment of migraine: a post hoc analysis of the randomized, sham-controlled, double-blind PRESTO trial (2018) (21)
- Evidence that PAR‐1 and PAR‐2 mediate prostanoid‐dependent contraction in isolated guinea‐pig gallbladder (2000) (21)
- Capsaicin releases calcitonin gene-related peptide from the human iris and ciliary body in vitro (1992) (21)
- Inhibition of bradykinin‐evoked trigeminal nerve stimulation by the non‐peptide bradykinin B2 receptor antagonist WIN 64338 in vivo and in vitro (1995) (21)
- Practical and clinical utility of non-invasive vagus nerve stimulation (nVNS) for the acute treatment of migraine: a post hoc analysis of the randomized, sham-controlled, double-blind PRESTO trial (2018) (21)
- The effects of repeated dermal application of capsaicin to the human skin on pain and vasodilatation induced by intradermal injection of acid and hypertonic solutions (1996) (21)
- Tachykinins contract the circular muscle of the human esophageal body in vitro via NK2 receptors. (1993) (21)
- Characterization of [3H]5-hydroxytryptamine uptake within rat cerebrovascular tree. (1985) (21)
- Hypertonic media produce Ca2+-dependent release of calcitonin gene-related peptide from capsaicin-sensitive nerve fibres in the rat urinary bladder (1991) (20)
- Ethanol potentiates the TRPV1-mediated cough in the guinea pig. (2009) (19)
- Local Application of Capsaicin for the Treatment of Cluster Headache and Idiopathic Trigeminal Neuralgia (1991) (19)
- Species-related variations in the effects of capsaicin on urinary bladder functions: relation to bladder content of substance P-like immunoreactivity (1987) (19)
- Characterization of tachykinin receptors in ferret trachea by peptide agonists and nonpeptide antagonists. (1993) (19)
- Pulmonary hypertension in smoking mice over-expressing protease-activated receptor-2 (2010) (19)
- Montelukast inhibits inflammatory responses in small airways of the Guinea-pig. (2008) (18)
- Effect of sensory denervation with capsaicin on liver fibrosis induced by common bile duct ligation in rat. (1990) (17)
- Mental Pain Questionnaire: An item response theory analysis. (2019) (17)
- Low pH medium induces calcium dependent release of CGRP from sensory nerves of guinea-pig dural venous sinuses. (1991) (17)
- Tachykinins mediate the potentiation of antigen-induced bronchoconstriction by cold air in guinea pigs. (1996) (17)
- Calcium and capsaicin- induced substance P release from peripheral terminals of primary sensory neurons (1988) (16)
- Protease‐activated receptor‐2 downregulation is associated to vitiligo lesions (2009) (16)
- TRPA1 mediates damage of the retina induced by ischemia and reperfusion in mice (2020) (16)
- Thiorphan increases capsaicin-evoked release of substance P from slices of dorsal spinal cord of guinea pig (1989) (16)
- Characterization of the endothelin receptor subtype mediating epithelium‐derived relaxant nitric oxide release from guinea‐pig trachea (1998) (16)
- Oxidative stress mediates thalidomide-induced pain by targeting peripheral TRPA1 and central TRPV4 (2020) (16)
- The role of TRP ion channels in migraine and headache (2021) (16)
- Kinins and kinin receptors in the nervous system (1995) (16)
- Tachykinins via Tachykinin NK2 receptor activation mediate ozone‐induced increase in the permeability of the tracheal mucosa in guinea‐pigs (2002) (16)
- β-adrenergic-blocking drugs and melanoma: current state of the art (2012) (15)
- Peripheral Nerve Resident Macrophages and Schwann Cells Mediate Cancer-Induced Pain (2021) (15)
- Corticotropin-releasing factor inhibits antigen-induced plasma extravasation in airways. (1995) (15)
- Differential activation of the epithelial and smooth muscle NK1 receptors by synthetic tachykinin agonists in guinea‐pig trachea (1997) (15)
- TRPA1 Mediates Aromatase Inhibitor-Evoked Pain by the Aromatase Substrate Androstenedione. (2016) (15)
- Neurokinin-1 receptor blockade and murine lung tumorigenesis. (2006) (15)
- The contribution of capsaicin-sensitive sensory nerves to xylene-induced visceral pain in conscious, freely moving rats (1988) (15)
- Effect of topical nasal treatment with capsaicin in vasomotor rhinitis (1988) (14)
- Dacarbazine alone or associated with melanoma‐bearing cancer pain model induces painful hypersensitivity by TRPA1 activation in mice (2020) (14)
- TRPA1 mediates the antinociceptive properties of the constituent of Crocus sativus L., safranal (2019) (14)
- Transient receptor potential ankyrin 1 contributes to somatic pain hypersensitivity in experimental colitis (2020) (14)
- Effect of thiorphan on the response of guinea-pig isolated urinary bladder to exogenous and endogenous tachykinins. (1990) (13)
- Release of sensory CGRP by hypertonic NaCl is not blocked by tetrodotoxin, omega-conotoxin, nifedipine and ruthenium red. (1992) (13)
- Contractile effect of endothelin on isolated iris sphincter muscle of the pig. (1989) (13)
- Distinct mechanisms underlying local antinociceptive and pronociceptive effects of natural alkylamides from Acmella oleracea compared to synthetic isobutylalkyl amide. (2018) (13)
- Rapid growth of Merkel cell carcinoma during etanercept treatment of psoriatic arthritis: cause or coincidence? (2011) (13)
- Clinical and microbiological efficacy of prulifloxacin for the treatment of chronic bacterial prostatitis due to Chlamydia trachomatis infection: results from a prospective, randomized and open-label study. (2010) (13)
- Abnormal Pressure Passive Dilatation of Cerebral Arterioles in the Elderly With Isolated Systolic Hypertension (2006) (13)
- Evidence for in vitro expression of B1 receptor in the mouse trachea and urinary bladder (1999) (13)
- Nedocromil sodium reduces allergen‐induced plasma extravasation in the guinea pig nasal mucosa by inhibition of tachykinin release (1995) (13)
- What is changing in chronic migraine treatment? An algorithm for onabotulinumtoxinA treatment by the Italian chronic migraine group (2020) (13)
- Proteinase‐activated receptor‐1 (PAR‐1) activation contracts the isolated human renal artery in vitro (2003) (13)
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- Substance P in the Human Iris: Possible Involvement in Echothiophate-Induced Miosis in Cluster Headache (1988) (13)
- Long-Term Effectiveness of Three Anti-CGRP Monoclonal Antibodies in Resistant Chronic Migraine Patients Based on the MIDAS score (2022) (13)
- Changes in grey matter volume and functional connectivity in cluster headache versus migraine (2019) (13)
- Loss of heterozygosis on IFN-alpha locus is a prognostic indicator of bacillus Calmette-Guerin response for nonmuscle invasive bladder cancer. (2010) (12)
- Migraine during COVID-19: Data from Second Wave Pandemic in an Italian Cohort (2021) (12)
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- Age-related changes in substance P and vasoactive intestinal polypeptide immunoreactivity in the rat stomach and small intestine. (1991) (11)
- Neuropeptides: brain messengers of many faces (2001) (11)
- Kallidin applied to the human nasal mucosa produces algesic response not blocked by capsaicin desensitization (1991) (11)
- Tachykinins, via NK1 receptor activation, play a relevant role in plasma protein extravasation evoked by allergen challenge in the airways of sensitized guinea-pigs (1992) (11)
- Bradykinin increases intracellular calcium levels in a human bronchial epithelial cell line via the B2 receptor subtype (1998) (11)
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- Chronic headaches and medication overuse (2010) (10)
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- Modulation of calcitonin gene-related peptide release evoked by bradykinin and electrical field stimulation in guinea-pig atria (1994) (8)
- Budesonide inhibits plasma extravasation induced by capsaicin and by substance P in the rat nasal mucosa (1993) (8)
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- Mechanisms of acute cough. (2004) (5)
- Epidemiology and determinants of chronic migraine: A real-world cohort study, with nested case-control analysis, in primary care in Italy (2019) (5)
- Mechanisms by which Lipid Derivatives and Proteinases Signal to Primary Sensory Neurons: Implications for Inflammation and Pain (2003) (5)
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- Periorbital Nociception in a Progressive Multiple Sclerosis Mouse Model Is Dependent on TRPA1 Channel Activation (2021) (4)
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- The contribution of capsaicin- sensitive sensory nerves to xylene-induced visceral pain in conscious, freely moving rats (1988) (3)
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- Unpredictable Sound Stress Model Causes Migraine-Like Behaviors in Mice With Sexual Dimorphism (2022) (2)
- Tachykinins, via NK-1 receptor activation, play a relevant role in plasma protein extravasation evoked by allergen challenge in the airways of sensitized guinea pigs (1992) (2)
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- The vanilliod-TRPV1 receptor antagonizing sulfonamidoverbindungen (2005) (0)
- BUSPIRONE MIOSIS. AUTHORS' REPLY (1995) (0)
- Neuropeptide release from slices of rat and guinea pig trigeminal ganglia: modulation by dihydroergotamine and sumatriptan (2000) (0)
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What Schools Are Affiliated With Pierangelo Geppetti?
Pierangelo Geppetti is affiliated with the following schools: