Prof. P. Brissot
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Prof. P. Brissot's Degrees
- PhD Molecular Biology Stanford University
- Masters Biochemistry Stanford University
- Bachelors Biology University of California, Berkeley
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(Suggest an Edit or Addition)Prof. P. Brissot's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A New Mouse Liver-specific Gene, Encoding a Protein Homologous to Human Antimicrobial Peptide Hepcidin, Is Overexpressed during Iron Overload* (2001) (1673)
- Mutations in HFE2 cause iron overload in chromosome 1q–linked juvenile hemochromatosis (2004) (958)
- Antioxidant and iron-chelating activities of the flavonoids catechin, quercetin and diosmetin on iron-loaded rat hepatocyte cultures. (1993) (627)
- Non-transferrin bound iron: a key role in iron overload and iron toxicity. (2012) (536)
- Insulin resistance-associated hepatic iron overload. (1999) (467)
- A new syndrome of liver iron overload with normal transferrin saturation (1997) (339)
- The discovery of the new haemochromatosis gene (2003) (327)
- Liver pathology in genetic hemochromatosis: a review of 135 homozygous cases and their bioclinical correlations. (1992) (293)
- Noninvasive prediction of fibrosis in C282Y homozygous hemochromatosis. (1998) (282)
- EASL International Consensus Conference on Haemochromatosis. (2000) (277)
- Efficient clearance of non-transferrin-bound iron by rat liver. Implications for hepatic iron loading in iron overload states. (1985) (244)
- The relationship between iron overload, clinical symptoms, and age in 410 patients with genetic hemochromatosis (1997) (240)
- C/EBPα Regulates Hepatic Transcription of Hepcidin, an Antimicrobial Peptide and Regulator of Iron Metabolism (2002) (238)
- Hemochromatosis: diagnosis and quantification of liver iron with gradient-echo MR imaging. (1994) (210)
- High yield preparation of isolated human adult hepatocytes by enzymatic perfusion of the liver. (1982) (207)
- Hepcidin levels in humans are correlated with hepatic iron stores, hemoglobin levels, and hepatic function. (2005) (192)
- Reversibility of hepatic fibrosis in treated genetic hemochromatosis: A study of 36 cases (2006) (192)
- Management of Hemochromatosis (1998) (190)
- Characterization of non-transferrin-bound iron clearance by rat liver. (1986) (176)
- Indication of liver transplantation in severe alcoholic liver cirrhosis: quantitative evaluation and optimal timing. (2002) (168)
- Clinical Features of Genetic Hemochromatosis in Women Compared with Men (1997) (167)
- Assessment of liver iron content in 271 patients: A reevaluation of direct and indirect methods (1981) (163)
- Quantification of non-transferrin-bound iron in the presence of unsaturated transferrin. (1999) (160)
- Preneoplastic significance of hepatic iron–free foci in genetic hemochromatosis: A study of 185 patients (1993) (159)
- Carcinoma of the Hepatic Hilus Surgical Management and the Case for Resection (1979) (157)
- Haemochromatosis (2003) (151)
- Differentiation Between Heterozygotes and Homozygotes in Genetic Hemochromatosis by Means of a Histological Hepatic Iron Index: A Study of 192 Cases (1993) (139)
- The origin and spread of the HFE-C282Y haemochromatosis mutation (2004) (139)
- Increased liver iron stores in patients with hepatocellular carcinoma developed on a noncirrhotic liver (1995) (138)
- The genetics of haemochromatosis. (1988) (136)
- Current approach to hemochromatosis. (2008) (133)
- Common variants in the BMP2, BMP4, and HJV genes of the hepcidin regulation pathway modulate HFE hemochromatosis penetrance. (2007) (132)
- Phenotypic expression of HFE mutations: a French study of 1110 unrelated iron-overloaded patients and relatives. (1999) (131)
- Redox active plasma iron in C282Y/C282Y hemochromatosis. (2005) (130)
- Liver fibrosis in genetic hemochromatosis. Respective roles of iron and non-iron-related factors in 127 homozygous patients. (1992) (122)
- Management of hemochromatosis. Hemochromatosis Management Working Group. (1998) (119)
- Determination of non-transferrin-bound iron in genetic hemochromatosis using a new HPLC-based method. (2000) (110)
- Serum ferritin as a possible marker of the hemochromatosis allele. (1979) (110)
- Comparative analysis of mouse hepcidin 1 and 2 genes: evidence for different patterns of expression and co‐inducibility during iron overload 1 (2003) (109)
- Duodenal mRNA expression of iron related genes in response to iron loading and iron deficiency in four strains of mice (2002) (108)
- Inactivation of the hemochromatosis gene differentially regulates duodenal expression of iron-related mRNAs between mouse strains. (2002) (107)
- A reappraisal of hepatic siderosis in patients with end-stage cirrhosis: practical implications for the diagnosis of hemochromatosis. (1997) (105)
- C/EBPalpha regulates hepatic transcription of hepcidin, an antimicrobial peptide and regulator of iron metabolism. Cross-talk between C/EBP pathway and iron metabolism. (2002) (104)
- Kinetic evaluation of free malondialdehyde and enzyme leakage as indices of iron damage in rat hepatocyte cultures. Involvement of free radicals. (1990) (103)
- A Phase 1/2, Dose-Escalation Trial of Deferasirox for the Treatment of Iron Overload in HFE-Related Hereditary Hemochromatosis (2010) (103)
- Venesection therapy of insulin resistance-associated hepatic iron overload. (2001) (95)
- Aceruloplasminemia: new clinical, pathophysiological and therapeutic insights. (2002) (94)
- Iron metabolism and related genetic diseases: A cleared land, keeping mysteries. (2016) (93)
- Strain and gender modulate hepatic hepcidin 1 and 2 mRNA expression in mice. (2004) (92)
- A genotypic study of 217 unrelated probands diagnosed as "genetic hemochromatosis" on "classical" phenotypic criteria. (1999) (91)
- Liver iron concentration and distribution in chronic hepatitis C before and after interferon treatment. (1997) (91)
- Serum α‐L‐Fucosidase: A New Marker for the Diagnosis of Primary Hepatic Carcinoma? (1984) (87)
- Iron and the liver: update 2008. (2008) (85)
- Chelation and mobilization of cellular iron by different classes of chelators. (1997) (84)
- A point mutation in the bulge of the iron-responsive element of the L ferritin gene in two families with the hereditary hyperferritinemia-cataract syndrome. (1998) (83)
- A new missense mutation in the L ferritin coding sequence associated with elevated levels of glycosylated ferritin in serum and absence of iron overload (2009) (81)
- Novel mutation in ferroportin 1 gene is associated with autosomal dominant iron overload. (2003) (80)
- Improvement in liver pathology of patients with β-thalassemia treated with deferasirox for at least 3 years. (2011) (76)
- Iron disorders of genetic origin: a changing world. (2011) (75)
- Current approaches to the management of hemochromatosis. (2006) (74)
- The Evaluation of Hyperferritinemia: An Updated Strategy Based on Advances in Detecting Genetic Abnormalities (2005) (72)
- Antioxidant and free radical scavenging activities of the iron chelators pyoverdin and hydroxypyrid-4-ones in iron-loaded hepatocyte cultures: comparison of their mechanism of protection with that of desferrioxamine. (1992) (70)
- EMQN best practice guidelines for the molecular genetic diagnosis of hereditary hemochromatosis (HH) (2015) (69)
- Interferon and ursodeoxycholic acid combined therapy in the treatmet of chronic viral C hepatitis: Results from a controlled randomized trial in 80 patients (1995) (69)
- Antiproliferative and apoptotic effects of O-Trensox, a new synthetic iron chelator, on differentiated human hepatoma cell lines. (2000) (69)
- Liver iron is a surrogate marker of severe fibrosis in chronic hepatitis C. (2007) (68)
- Treatment of hepatocellular carcinoma (HCC) with systemic chemotherapy combining epirubicin, cisplatinum and infusional 5-fluorouracil (ECF regimen) (2002) (68)
- Effect of alcohol consumption on liver stiffness measured by transient elastography. (2013) (66)
- Idiopathic hemochromatosis and iron overload in alcoholic liver disease: differentiation by HLA phenotype. (1977) (66)
- [Non surgical treatment of hepatocellular carcinoma]. (1992) (65)
- Heterozygous Mutations in BMP6 Pro-peptide Lead to Inappropriate Hepcidin Synthesis and Moderate Iron Overload in Humans. (2016) (65)
- Iron, hepcidin, and the metal connection (2014) (64)
- A new mutation in the hepcidin promoter impairs its BMP response and contributes to a severe phenotype in HFE related hemochromatosis (2009) (64)
- Prediction of liver fibrosis in patients with features of the metabolic syndrome regardless of alcohol consumption (2004) (63)
- Clinical Consequences of New Insights in the Pathophysiology of Disorders of Iron and Heme Metabolism. (2000) (61)
- Sex and acquired cofactors determine phenotypes of ferroportin disease. (2011) (61)
- Elevated parathyroid hormone 44-68 and osteoarticular changes in patients with genetic hemochromatosis. (1999) (60)
- Assessment of liver iron content in 271 patients: a reevaluation of direct and indirect methods. (1981) (58)
- Ultrastructural sequences during liver iron overload in genetic hemochromatosis. (1997) (57)
- Natural and synthetic STAT3 inhibitors reduce hepcidin expression in differentiated mouse hepatocytes expressing the active phosphorylated STAT3 form (2010) (57)
- Increase in glycosylated and nonglycosylated serum ferritin in chronic alcoholism and their evolution during alcohol withdrawal. (1991) (52)
- Evaluation of computed tomography in the assessment of liver iron overload : A study of 46 cases of idiopathic hemochromatosis (1989) (50)
- Magnetic resonance imaging and assessment of liver iron content in genetic hemochromatosis. (1992) (50)
- Iron may induce both DNA synthesis and repair in rat hepatocytes stimulated by EGF/pyruvate. (1997) (49)
- Hereditary hemochromatosis: patient experiences of the disease and phlebotomy treatment (2011) (47)
- Idiopathic hemochromatosis: A study of biochemical expression in 247 heterozygous members of 63 families: Evidence for a single major HLA-linked gene (1980) (46)
- Fiber evanescent wave spectroscopy using the mid-infrared provides useful fingerprints for metabolic profiling in humans. (2009) (46)
- The new orally active iron chelator ICL670A exhibits a higher antiproliferative effect in human hepatocyte cultures than O-trensox. (2006) (45)
- A multi-disciplinary approach to treating hepatitis C with interferon and ribavirin in alcohol-dependent patients with ongoing abuse. (2012) (44)
- A novel N491S mutation in the human SLC11A2 gene impairs protein trafficking and in association with the G212V mutation leads to microcytic anemia and liver iron overload. (2011) (44)
- Pathophysiology and classification of iron overload diseases; update 2018. (2019) (44)
- Second Round Robin for plasma hepcidin methods : First steps toward harmonization (2012) (44)
- Liver transplantation normalizes serum hepcidin level and cures iron metabolism alterations in HFE hemochromatosis (2014) (43)
- Aminotransferase Levels and Silymarin in de novo Tacrine-Treated Patients with Alzheimer’s Disease (1999) (43)
- Miscellaneous non-inflammatory musculoskeletal conditions. Haemochromatosis: the bone and the joint. (2011) (43)
- Optimizing the diagnosis and the treatment of iron overload diseases (2016) (43)
- Antiproliferative and apoptotic effects in rat and human hepatoma cell cultures of the orally active iron chelator ICL670 compared to CP20: a possible relationship with polyamine metabolism (2007) (43)
- Iron overload promotes Cyclin D1 expression and alters cell cycle in mouse hepatocytes. (2006) (43)
- Anemia in β-thalassemia patients targets hepatic hepcidin transcript levels independently of iron metabolism genes controlling hepcidin expression (2008) (42)
- Polymorphisms in the HFE Gene (1999) (41)
- Iron overload of the liver in the baboon. An ultrastructural study. (1985) (40)
- Hepatitis B virus infection markers in genetic haemochromatosis. A study of 272 patients. (1991) (39)
- Carbonyl-iron supplementation induces hepatocyte nuclear changes in BALB/CJ male mice. (1999) (38)
- Daily regulation of serum and urinary hepcidin is not influenced by submaximal cycling exercise in humans with normal iron metabolism (2009) (38)
- Therapeutic recommendations in HFE hemochromatosis for p.Cys282Tyr (C282Y/C282Y) homozygous genotype (2018) (38)
- The clinical relevance of new insights in iron transport and metabolism. (2004) (38)
- The labile iron pool of hepatocytes in chronic and acute iron overload and chelator-induced iron deprivation. (2002) (37)
- Ferroportin Diseases: Functional Studies, a Link Between Genetic and Clinical Phenotype (2013) (37)
- Regulation of ferritin and transferrin receptor expression by iron in human hepatocyte cultures. (1993) (36)
- Non-HFE hemochromatosis: pathophysiological and diagnostic aspects. (2014) (36)
- In vitro demonstration of synergy between radionuclide and chemotherapy. (1998) (36)
- Non‐invasive assessment of liver fibrosis in C282Y homozygous HFE hemochromatosis (2015) (34)
- Simultaneous measurements of conjugated dienes and free malondialdehyde, used as a micromethod for the evaluation of lipid peroxidation in rat hepatocyte cultures. (1993) (34)
- HFE based re-evaluation of heterozygous hemochromatosis. (2002) (34)
- Iron mobilisation and cellular protection by a new synthetic chelator O-Trensox. (1998) (33)
- Antiproliferative effect of deferiprone on the Hep G2 cell line. (1998) (33)
- Mössbauer spectroscopy study of iron overloaded livers. (1985) (29)
- Evaluation of computed tomography in the assessment of liver iron overload. A study of 46 cases of idiopathic hemochromatosis. (1989) (28)
- Stearoyl coenzyme A desaturase 1 expression and activity are increased in the liver during iron overload. (2001) (28)
- Serum alpha-L-fucosidase: a new marker for the diagnosis of primary hepatic carcinoma? (1984) (28)
- Hepcidin in iron metabolism. (2005) (28)
- Hemochromatosis after the gene discovery: revisiting the diagnostic strategy. (1998) (27)
- Hepatocyte iron loading capacity is associated with differentiation and repression of motility in the HepaRG cell line. (2006) (27)
- Letters to the Editor: Non-alcoholic steatohepatitis with iron: part of insulin resistanceassociated hepatic iron overload? (2000) (27)
- Genetics of Hemochromatosis: HLA Association and Mode of Inheritance a (1988) (25)
- Hemochromatosis classification: update and recommendations by the BIOIRON Society. (2021) (25)
- Uremia and the liver. I. The liver and erythropoiesis in chronic renal failure. (1981) (25)
- Clinical aspects of hemochromatosis. (2000) (24)
- Low penetrant hemochromatosis phenotype in eight families: no evidence of modifiers in the MHC region. (2001) (24)
- Comparative study between biochemical and histological methods and image analysis in liver iron overload. (1982) (23)
- EPR study of antioxidant activity of the iron chelators pyoverdin and hydroxypyrid-4-one in iron-loaded hepatocyte culture: comparison with that of desferrioxamine. (1995) (23)
- Genetic hemochromatosis: Pathophysiology, diagnostic and therapeutic management. (2017) (23)
- Hypovitaminemia A in idiopathic hemochromatosis and hepatic cirrhosis. Role of retinol-binding protein and zinc. (1978) (23)
- Effects of deferasirox and deferiprone on cellular iron load in the human hepatoma cell line HepaRG (2010) (23)
- Rare anemias due to genetic iron metabolism defects. (2018) (23)
- Deferoxamine arrests in vitro the proliferation of porcine hepatocyte in G1 phase of the cell cycle. (2008) (22)
- Role of non-transferrin-bound iron in the pathogenesis of iron overload and toxicity. (2002) (22)
- GATA-4 transcription factor regulates hepatic hepcidin expression. (2011) (22)
- Biochemical aspects of α‐L‐fucosidase in hepatocellular carcinoma (1989) (21)
- Ascorbic acid status in idiopathic hemochromatosis. (1978) (21)
- Diagnostic evaluation of hereditary hemochromatosis (HFE and non-HFE). (2014) (21)
- Magnetic resonance iron-free nodules in genetic hemochromatosis (1999) (21)
- Reinforced interferon alpha‐2b and ribavirin is more effective than standard combination therapy in the retreatment of chronic hepatitis C previously nonresponsive to interferon: a randomized trial (2003) (20)
- Inhibition of iron toxicity in rat and human hepatocyte cultures by the hydroxypyridin-4-ones CP20 and CP94. (1995) (20)
- Variable age of onset and clinical severity in transferrin receptor 2 related haemochromatosis: novel observations (2013) (20)
- Serum ceruloplasmin and ferroxidase activity are not decreased in hepatic failure related to alcoholic cirrhosis: clinical and pathophysiological implications. (2004) (20)
- Novel orally active iron chelators (3-hydroxypyridin-4-ones) enhance the biliary excretion of plasma non-transferrin-bound iron in rats. (1997) (20)
- Inhibition of hepatitis B virus production associated with high levels of intracellular viral DNA intermediates in iron-depleted HepG2.2.15 cells. (2001) (19)
- Non-alcoholic steatohepatitis with iron: part of insulin resistance-associated hepatic iron overload? (2000) (19)
- Mouse genetic background impacts both on iron and non-iron metals parameters and on their relationships (2015) (18)
- Too much iron: A masked foe for leukemias. (2019) (18)
- Diagnosit value of erythrocyte-free polyamines and histaminemia in malignant hepatic tumors and in liver cirrhosis (1985) (18)
- Serum Transferrin Saturation Increase Is Associated With Decrease of Antibacterial Activity of Serum in Patients With HFE-Related Genetic Hemochromatosis (2008) (18)
- Iron induction of ferritin synthesis and secretion in human hepatoma cell (Hep G2) cultures. (2008) (18)
- Intestinal absorption and enterohepatic cycling of biliary iron originating from plasma non‐transferrin‐bound iron in rats (1997) (18)
- Low hepatic iron concentration: evaluation of two complementary methods, colorimetric assay and iron histological scoring. (1999) (18)
- Iron excess treatable by copper supplementation in acquired aceruloplasminemia: a new form of secondary human iron overload? (2009) (18)
- Ethanol effect on cell proliferation in the human hepatoma HepaRG cell line: relationship with iron metabolism. (2011) (17)
- The interaction of iron and the genome: For better and for worse. (2017) (17)
- Serum ceruloplasmin and ferroxidase activity are decreased in HFE C282Y homozygote male iron-overloaded patients. (2002) (17)
- Acute infusions of bile salts increase biliary excretion of iron in iron-loaded rats. (1991) (17)
- Uremia and the liver. II. Drugs and the liver in the uremic patient. (1981) (16)
- A pilot study of iron depletion as adjuvant therapy in chronic hepatitis C patients not responding to interferon (1999) (16)
- Alcohol induction of ferritin expression in a human hepatoblastoma cell line (HEP G2). (1990) (16)
- Redox active plasma iron in C 282 Y / C 282 Y hemochromatosis (2005) (16)
- Idiopathic hemochromatosis: a study of biochemical expression in 247 heterozygous members of 63 families: evidence for a single major HLA-linked gene. (1980) (16)
- Haemochromatosis : The bone and the joint (16)
- Traditional Management of Liver Disorders (2012) (15)
- Rare HFE variants are the most frequent cause of hemochromatosis in non‐c282y homozygous patients with hemochromatosis (2016) (15)
- Ceruloplasmin deficiency does not induce macrophagic iron overload: lessons from a new rat model of hereditary aceruloplasminemia (2019) (14)
- Liver iron overload is associated with elevated SHBG concentration and moderate hypogonadotrophic hypogonadism in dysmetabolic men without genetic haemochromatosis. (2011) (14)
- Intestinal absorption of iron in HFE-1 hemochromatosis: local or systemic process? (2004) (14)
- Respective value of alkaline phosphatase, gamma-glutamyl transpeptidase and 5' nucleotidase serum activity in the diagnosis of cholestasis: a prospective study of 80 patients. (2000) (14)
- Is the HLA‐linked haemochromatosis allele implicated in idiopathic refractory sideroblastic anaemia? (1985) (13)
- Transient transcriptional inhibition of the transferrin gene by cyclic AMP (1985) (13)
- Regulation of ferritin expression by alcohol in a human hepatoblastoma cell line and in rat hepatocyte cultures. (1995) (13)
- Use of adult human hepatocytes in primary culture for the study of clometacin-induced immunoallergic hepatitis. (1991) (13)
- Effects of phlebotomy therapy on cytochrome P450 2e1 activity and oxidative stress markers in dysmetabolic iron overload syndrome: a randomized trial (2006) (12)
- Effects of iron overload on transferrin secretion by cultured fetal rat hepatocytes (1989) (12)
- Hemochromatosis at the intersection of classical medicine and molecular biology. (2001) (11)
- Inhibition of iron overload toxicity in rat hepatocyte cultures by pyoverdin Pf, the siderophore of Pseudomonas fluorescens. (1992) (11)
- Hemochromatosis: Clinical spectrum of hepatic disease in hemochromatosis (2000) (11)
- A pilot study of iron depletion as adjuvant therapy in chronic hepatitis C patients not responding to interferon. (1999) (11)
- [Hyper-ferritinemia and Gaucher disease]. (1996) (11)
- Regulation of ferritin expression by alcohol in a human hepatoblastoma cell line and in rat hepatocyte cultures (1995) (11)
- Biliary excretion of plasma non-transferrin-bound iron in rats: pathogenetic importance in iron-overload disorders. (1994) (11)
- No increased seroprevalence of anti-Yersinia antibodies in patients with type 1 (C282Y/C282Y) hemochromatosis (2007) (10)
- An HLA-All association with the hemochromatosis allele? (1983) (10)
- [Hyperferritinemia not related to hemochromatosis]. (2009) (10)
- Iron load increases ferritin synthesis and secretion in adult human hepatocyte cultures. (2008) (10)
- The importance of the general practitioner as an information source for patients with hereditary haemochromatosis. (2014) (10)
- Iron-mediated effect of alcohol on hepatocyte differentiation in HepaRG cells. (2013) (10)
- Iron overload and the biliary route. (1994) (10)
- Increase in cellular pool of low-molecular-weight iron during ethanol metabolism in rat hepatocyte cultures (2007) (10)
- Iron and platelets: A subtle, under‐recognized relationship (2021) (10)
- Interferon and ursodeoxycholic acid combined therapy in chronic viral C hepatitis: controlled randomized trial in 203 patients. (2000) (10)
- Iron as a Therapeutic Target in HFE-Related Hemochromatosis: Usual and Novel Aspects (2018) (10)
- [The cardiomyopathy of idiopathic hemochromatosis]. (1978) (10)
- Lysosomal enzyme activities during ageing of adult human liver cell lines (1979) (9)
- Diagnosis and current treatments for primary iron overload (2007) (9)
- Molecular diagnosis of genetic iron-overload disorders (2010) (9)
- Iron mobilization, cytoprotection, and inhibition of cell proliferation in normal and transformed rat hepatocyte cultures by the hydroxypyridinone CP411, compared to CP20: a biological and physicochemical study. (2001) (9)
- Chronic iron overload inhibits protein secretion by adult rat hepatocytes maintained in long-term primary culture. (1989) (9)
- Low flow continuous peritoneal dialysis in acute renal failure. (1981) (9)
- Evaluation of a liver transplant by Tc-99m dimethyl-IDA scintigraphy. (1980) (9)
- Serum increase and liver overexpression of carbohydrate 19.9 antigen in patients with genetic haemochromatosis. (1994) (9)
- Involvement of polyamines in iron(III) transport in human intestinal Caco-2 cell lines (2013) (9)
- Iron Chelation Therapy with Deferasirox (Exjade®, ICL670) or Deferoxamine Results in Reduced Hepatocellular Inflammation and Improved Liver Function in Patients with Transfusion-Dependent Anemia. (2005) (9)
- An HLA‐All Assoiciation with the hemochromatosis allele? (1983) (9)
- [Epidemiology of hepatitis C virus infection in 1,304 HCV positive patients: variations according to the origin of transmission and year of diagnosis]. (1998) (8)
- Hereditary hypotransferrinemia can lead to elevated transferrin saturation and, when associated to HFE or HAMP mutations, to iron overload. (2015) (8)
- Spleen iron, molybdenum, and manganese concentrations are coregulated in hepcidin‐deficient and secondary iron overload models in mice (2019) (8)
- MRI quantification of splenic iron concentration in mouse (2010) (8)
- Modulation of albumin secretion by ornithine alpha-ketoglutarate in adult rat hepatocyte cultures and a human hepatoma cell line (HepG2). (1989) (8)
- High vascular endothelial growth factor (VEGF) expression in chemically-induced hepatic microcancers in mice. (2002) (8)
- Biochemical aspects of alpha-L-fucosidase in hepatocellular carcinoma. (1989) (8)
- 187 A PHASE I/II, OPEN-LABEL, DOSE-ESCALATION TRIAL USING THE ONCE-DAILY ORAL CHELATOR DEFERASIROX TO TREAT IRON OVERLOAD IN HFE-RELATED HEREDITARY HEMOCHROMATOSIS: FINAL RESULTS (2009) (8)
- Modulation of cell proliferation and polyamine metabolism in rat liver cell cultures by the iron chelator O-trensox (2006) (8)
- alpha-Fetoprotein screening in patients with idiopathic hemochromatosis and liver cirrhosis. (1977) (8)
- Iron mobilization, cytoprotection, and inhibition of cell proliferation in normal and transformed rat hepatocyte cultures by the hydroxypyridinone CP411, compared to CP20: a biological and physicochemical study (2004) (8)
- A Phase I/II, Open-Label, Dose-Escalation Trial of Once-Daily Oral Chelator Deferasirox to Treat Iron Overload in HFE-Related Hereditary Hemochromatosis: Final Results of the Core Study. (2009) (7)
- Hepcidin induction limits mobilisation of splenic iron in a mouse model of secondary iron overload. (2010) (7)
- [Hepatic manifestations of Horton's disease]. (1978) (6)
- High rate of long‐term virological response after a 1‐year course of interferon ± ribavirin in chronic hepatitis C relapsers. Results of a 191 patients randomized trial (2003) (6)
- Transferrin Electronic Detector for Iron Disease Diagnostics (2006) (6)
- [Importance of liver puncture biopsy and endoscopic retrograde cholangiography in patients with chronic anicteric unexplained cholestasis. A retrospective study in 79 patients]. (1999) (6)
- In patients with cirrhosis, serum albumin determination should be carried out by immunonephelometry rather than by protein electrophoresis. (1999) (6)
- [Histochemical detection of hepatic iron. A comparative study of four stains]. (1992) (6)
- [Hereditary hemochromatosis: presenting manifestations and diagnostic delay]. (2014) (6)
- Uremia and the liver. III. Uremia and hepatic metabolism of carbohydrates, lipids, and proteins. (1981) (5)
- Diagnostic value of erythrocyte-free polyamines and histaminemia in malignant hepatic tumors and in liver cirrhosis. (1985) (5)
- Diagnostic d'une hyperferritinémie (1998) (5)
- Transcripts of ceruloplasmin but not hepcidin, both major iron metabolism genes, exhibit a decreasing pattern along the portocentral axis of mouse liver. (2008) (5)
- Inhibition of iron toxicity in rat hepatocyte cultures by pyoverdin Pa A, the peptidic fluorescent siderophore of Pseudomonas aeruginosa. (1993) (5)
- [Letter: Heridity of hemochromatosis: its relation with HL-A system]. (1976) (5)
- Novel mutations in the bone morphogenetic protein 6 gene in patients with iron overload and non-homozygous genotype for the HFE p.Cys282Tyr mutation. (2020) (5)
- [Haemochromatoses. New understanding, new treatments]. (2009) (5)
- Clinical management of hemochromatosis: current perspectives (2017) (5)
- Portable hemoglobinometer is a reliable technology for the follow-up of venesections tolerance in hemochromatosis. (2015) (5)
- What’s Important and New in Hemochromatosis? (2020) (5)
- [Normal iron metabolism]. (2006) (5)
- Short-term prednisolone followed by recombinant human alpha-interferon alone or combined with adenine-arabinoside in chronic hepatitis B. A prospective and randomized trial. (1991) (5)
- Genetic hemochromatosis update. (2005) (5)
- Design of an Ongoing Phase I/II Open-Label, Dose-Escalation Trial Using the Oral Chelator Deferasirox To Treat Iron Overload in HFE-Related Hereditary Hemochromatosis (HH). (2007) (5)
- [Regenerative nodular hyperplasia in scleroderma : a new case]. (1984) (5)
- Diagnosis and treatment of HFE-haemochromatosis (2009) (4)
- [Non-HFE related hereditary iron overload]. (2005) (4)
- The relationship between fatty acid peroxidation and α-tocopherol consumption in isolated normal and transformed hepatocytes (1993) (4)
- Correlation between Dose-Dependent Reductions in Serum Transaminase (ALT) and Serum Ferritin Levels during Long-Term Chelation Therapy with Deferasirox (Exjade®, ICL670). (2006) (4)
- HFE-Related Hemochromatosis in a Chinese Patient: The First Reported Case (2020) (4)
- Regulation of Systemic Iron Transport and Storage (2002) (4)
- Quality of life scores differs between genotypic groups of patients with suspected hereditary hemochromatosis (2018) (4)
- EASL International Consensus Conference on Haemochromatosis Co-sponsored by the World Health Organization * (4)
- Fatal congestive heart failure with deferiprone. (2008) (4)
- Electrical detection of very low content of transferrin in view of iron metabolism characterization (2008) (4)
- Hemochromatosis: a model of metal-related human toxicosis (2016) (4)
- Hereditary hemochromatosis (2013) (3)
- [Iron metabolism and tools for the iron status assessment]. (2012) (3)
- [Iron overload and HFE gene]. (1999) (3)
- [Hepcidin: small molecule, large future]. (2003) (3)
- [Iron in the era of molecular biology]. (1999) (3)
- [HFE hemochromatosis: pathogenic and diagnostic approach]. (2005) (3)
- [Porphyrins and idiopathic hemochromatosis. Study of 32 cases (author's transl)]. (1978) (3)
- How we interpret transferrin saturation (2017) (3)
- [A new case of hepatitis due to glafenine]. (1982) (3)
- Reduction of liver iron content following tratment of chronic hepatitis C (1995) (3)
- Hemochromatosis: Management of hemochromatosis (2000) (3)
- [Value of ultrasound-guided cytopuncture in the diagnosis of tumors in cirrhosis. Study of 29 cases]. (1985) (3)
- [Treatment and prevention of chronic iron overload (author's transl)]. (1981) (3)
- [Management of hemochromatosis linked to HFE gene]. (2007) (3)
- Laboratory medicine and iron overload: diagnostic and therapeutic aspects (2020) (2)
- [Antiviral treatment of chronic hepatitis B]. (1987) (2)
- [Hereditary iron overload]. (2010) (2)
- Deferasirox Improves Liver Pathology In β-Thalassemia Patients with Transfusional Iron Overload (2010) (2)
- [Decrease of cholesterolemia and apolipoprotein B in chronic viral hepatitis C with massive steatosis]. (1994) (2)
- Haemochromatosis and HFE gene. (1999) (2)
- Fractional clearance of bromosulfonephthalein and metabolic clearance of antipyrine. Correlative study in liver diseases. (1984) (2)
- [Super-paramagnetic iron oxide: an MRI contrast media for the reticuloendothelial system]. (1989) (2)
- Inhibition of iron toxicity in human hepatocyte cultures by pyoverdins Pa A and Pf, the peptidic siderophores of Pseudomonas aeruginosa and fluorescens. (2008) (2)
- [Association of sarcoidosis and primary biliary cirrhosis: review of the literature apropos of a new case]. (1990) (2)
- [Sinusoidal hepatic fibrosis and diabetes mellitus]. (1981) (2)
- [Transmission of viruses (from A to E) and prevention]. (1990) (2)
- [Non-transferrin-bound iron and hepatic iron load]. (1992) (2)
- Heterozygous Mutations in BMP 6 Pro-peptide Lead to Inappropriate Hepcidin Synthesis and Moderate Iron Overload in Humans Running title : BMP 6 , gene for moderate hemochromatosis (2016) (2)
- [Respective value of serum activity of alkaline phosphatase, gamma-glutamyl transpeptidase and 5'-nucleotidase in the diagnosis of intra- and extrahepatic cholestasis]. (1997) (2)
- 189 EFFECT OF IRON CHELATION THERAPY WITH DEFERASIROX (EXJADE®, ICL670) OR DEFEROXAMINE ON HEPATOCELLULAR INFLAMMATION AND LIVER FUNCTION IN PATIENTS WITH TRANSFUSIONDEPENDENT ANEMIA (2008) (2)
- Long term follow up of chronic hepatitis by serial liver biopsies in HBs positive haemodialysis patients. Role of hepatotoxic drugs. (1978) (2)
- [Hepcidin: the Grail of iron metabolism]. (2002) (2)
- [Iron metabolism]. (2000) (2)
- [Course of the prolyl hydroxylase activity and the quantity of collagen amino acids in the liver during a 2-year experimental chronic iron overload in baboons]. (1983) (2)
- Cytoprotection and iron mobilization in rat hepatocyte cultures by a new synthetic dihydroxamate chelator. (1999) (2)
- [Diagnosis of hemochromatosis in the era of gentic testing]. (2000) (2)
- Regulation of ferritin and transferrin receptor expression by iron overload in adult human hepatocytes and a human hepatoblastoma cell line (Hep G2) (1990) (2)
- [Hepatic fascioliasis. Echotomographic appearance at an early stage]. (1983) (2)
- Chromosomal aberrations in patients with primary biliary cirrhosis (1990) (2)
- Chronic liver iron overload in the baboon by ferric nitrilotriacetate (1987) (2)
- [Interactions of alcohol and iron proteins]. (1989) (2)
- [Porphyria from the view of the hepatologist]. (1990) (2)
- [Symptomatic treatment of pruritus in cholestasis]. (1997) (2)
- [Alpha-L-fucosidase. A new marker of primary liver cancer?]. (1983) (1)
- [Treatment of hemochromatosis and its complications]. (2007) (1)
- Inhibition of iron overload toxicity by pyoverdins in adult rat hepatocyte cultures (1991) (1)
- CHOLANGITE SCLEROSANTE PRIMITIVE (1990) (1)
- [Excretion of HBs and HBe antigens by normal human adult hepatocytes infected in vitro by hepatitis B virus]. (1983) (1)
- Differentiation between heterozygotes and homozygotes in genetic hemochromatosis by means of a morphological iron index: a study of 192 cases (1992) (1)
- [Management in front of hypersideremia]. (1991) (1)
- 181 DOSE-DEPENDENT REDUCTIONS IN SERUM FERRITIN CORRELATE WITH CHANGES IN SERUM TRANSAMINASE LEVELS DURING LONG-TERM IRON CHELATION THERAPY WITH DEFERASIROX (EXJADE®, ICL670) (2008) (1)
- [Malarial hepatitis. Apropos of a case]. (1977) (1)
- [Histologic quantification of hemochromatotic and non-hemochromatotic liver siderosis. A stidu of 254 liver biopsies]. (1997) (1)
- [Pathophysiology and genetics of classic HFE (type 1) hemochromatosis]. (2007) (1)
- [Diagnosis of hyperferritinemia]. (1998) (1)
- [Current data on iron metabolism]. (1999) (1)
- High rate lond term response after one year interferon (IFN) plus ribavirine treatment for hepatitis C relapsers. Results of a controlled randomized study in 191 patients (2001) (1)
- [Histologic classification of hepatic siderosis (author's transl)]. (1981) (1)
- [Randomized trial of elliptinium acetate and tamoxifen in the treatment of inoperable hepatocellular carcinoma]. (1986) (1)
- [Family screening strategy for genetic hemochromatosis]. (1990) (1)
- Effect of ornithine on albumin and transferrin secretions in rat and human hepatocyte cultures (1990) (1)
- [Sinusoid dilatation and the use of oral contraceptives. Apropos of a case with a review of the literature]. (1988) (1)
- [Iron metabolism]. (2006) (1)
- HAMP promoter mutation nc.-153 C>T in 785 HEIRS Study participants: author reply (2009) (1)
- [Practical use of genetic markers other than C282Y in iron overload disorders]. (2002) (1)
- [IRON OVERLOAD: BETTER UNDERSTANDING, BETTER CARE]. (2015) (1)
- Effect of ursodeoxycholic acid on liver iron stores and distribution in rats with normal or iron-supplemented diet. (2008) (1)
- [The value of computerized tomography in the assessment of hepatic iron overload in genetic hemochromatosis]. (1990) (1)
- [Gaucher's disease in Rennes University hospital: a 10-year retrospective study]. (2009) (1)
- Iron induction of ferritin synthesis and secretion in a human hepatoblastoma cellline (HepG2) (1989) (1)
- Abstracts of the Research Forum of the ‘Société Nationale Française de Gastroentérologie’ (1977) (1)
- Effect of ornithine on transferrin secretion of rat and human hepatocyte cultures. (2008) (1)
- Chronic hepatic cytolysis revealing a pheochromocytoma. (2012) (1)
- Molecular Testing in Hemochromatosis (2017) (1)
- [Chronic alcoholic liver disease. Ionized blood calcium measurements in 24 patients (author's transl)]. (1980) (0)
- 428 DIAGNOSIS OF HEREDITARY HEMOCHROMATOSIS AND INVOLVEMENT OF PATIENTS IN TREATMENT DECISION MAKING: AN INTERNATIONAL QUANTITATIVE SURVEY OF 210 PATIENTS (2009) (0)
- Non Invasive Assessment of Hepatic Fibrosis by Measurement of Liver Stiffness in Post Transfusional Iron Overload: Preliminary Results in 15 Patients. (2006) (0)
- Monoclonal anti‐transferrin antibody: A paradigm for better understanding of iron metabolism (2015) (0)
- [Comparative study of 3 serum markers of primary liver cancer: ferritin, alpha-fetoprotein and alpha-fucosidase]. (1987) (0)
- [A study of lysosomal enzyme activities in serum and leukocytes in chronic hepatic disease (author's transl)]. (1980) (0)
- Selected abstracts from the meeting of the French association for the study of the liver Strasbourg, France, 28–30 November, 1985 (1986) (0)
- [Acute hemolysis and kidney failure disclosing Wilson's disease. Diagnosis and therapeutic indications]. (1981) (0)
- Hla in iron overload (1982) (0)
- [Genetic screening of hemochromatosis]. (1998) (0)
- SHORT FORM HEALTH SURVEY (SF-36) DIFFERS BETWEEN GENOTYPIC GROUPS OF PATIENTS WITH SUSPECTED HEREDITARY HEMOCHROMATOSIS (2017) (0)
- Iron Overload Diagnosis and Management Among Clinicians: International Survey Showing Gaps In Knowledge and Need for Continuing Educational Programs (2010) (0)
- P743 IMPACT OF BASELINE SERUM FERRITIN ON SURVIVAL OF PATIENTS WITH CHRONIC HEPATITIS C AFTER A 15 YEARS FOLLOW-UP (2014) (0)
- [Update on hemochromatosis]. (2004) (0)
- Fatal congestive heart failure with deferiprone: Answer to letter from Ladis et al. (2009) (0)
- Electrical quantification of low concentrations of specific protein in complex biological solutions (2008) (0)
- [How to confirm and treat hemochromatosis in 2002?]. (2002) (0)
- Hemocromatosis: a changing world. (2016) (0)
- [Hemochromatoses: a changing world]. (2014) (0)
- [Liver abscess caused by Yersinia enterocolitica with spontaneously favourable course]. (1995) (0)
- [Biologic update on hemochromatosis]. (1985) (0)
- [Acute cholangitis caused by an amoxicillin-clavulanic acid combination]. (1995) (0)
- Altered Hepcidin Regulation in Hereditary Hemochromatosis (2006) (0)
- [Idiopathic hemochromatosis in 1984]. (1985) (0)
- [Peliosis hepatis after treatment with androgens. A recent case]. (1978) (0)
- Fiber evanescentwave spectroscopy using mid infrared give useful finger print for metabolic profiling in human. (2009) (0)
- The Monoclonal Anti-Transferrin Antibody Syndrome: A Way for a Better Understanding of Iron Metabolism (2016) (0)
- Quality of Life Scores Remained Different among the Genotypic Groups of Patients with Suspected Hemochromatosis, Even after Treatment Period (2022) (0)
- [Metabolic cirrhosis (hemochromatosis, Wilson's disease, erythropoietic protoporphyria)]. (1991) (0)
- The pioneering role of the Rennes School in haemochromatosis (2017) (0)
- Suspended-gate Thin Film Transistor as protein sensor: from technological process to functionalization and transferin calibration (2008) (0)
- Sinusoid dilatations and intake of oral contraceptives. Report of one case with review of the literature (1988) (0)
- Respective value of alkaline phosphatase, GGT and 5′ nucleotidase serum activity in the diagnosis of cholestasis: A prospective study of 65 patients (1998) (0)
- [Management of a family with genetic hemochromatosis]. (1996) (0)
- [How should hepatitis C be treated? Treatment of chronic hepatitis C with therapeutic combinations]. (1997) (0)
- [Genetic iron overload diseases: a deeply changing world]. (2006) (0)
- DIAGNOSTIC AND TREATMENT OF INHERITED HAEMOCHROMATOSIS (2009) (0)
- [Biological markers of hepatocellular carcinoma]. (1987) (0)
- Management of Liver Complications in Haemoglobinopathies (2014) (0)
- [Iron metabolism and its exploration in clinical biology]. (1998) (0)
- Association of pulmonary aspergillosis and mucoviscidosis. 1 case (1978) (0)
- In patients with cirrhosis, should serum albumin determination be carried out by immunonephelemetry or by protein electrophoresis? (1998) (0)
- Diagnosis of genetic haemochromatosis (2001) (0)
- L’hémochromatose : expression et diagnostic (1999) (0)
- Evaluation of liver iron by computed tomography in 45 cases of genetic hemochromatosis with special reference to mild iron overload (1987) (0)
- Use of valproic acid or its derivatives in the treatment of deficiencies in hepcidin and their consequences (2014) (0)
- [Cholestasis of pregnancy. A new indication for plasma exchange]. (1982) (0)
- Comparative efficacy of oral iron chelators on the biliary excretion of plasma non-transferrin-bound iron in normal and iron overloaded rats (1992) (0)
- Risk factors for hepatocellular carcinoma (HCC) in HCV cirrhotic patients undergoing liver transplantation (1998) (0)
- Involvement of polyamines in iron(III) transport in human intestinal Caco-2 cell lines (2013) (0)
- [Controlling hemochromatosis, the course of hepcidine]. (2007) (0)
- Atoh8 Mrna Levels Do Not Regulate Hepcidin Expression in Human Hepatocyte Cultures (2016) (0)
- [Idiopathic hemochromatosis as seen by the practitioner]. (1981) (0)
- 1049 Hepatic iron concentration and total body iron stores in genetic hemochromatosis and thalassemia major (2003) (0)
- 580 Iron and chronic hepatitis C: clinical, biological, histological correlations and impaact on fibrosis progression (2003) (0)
- Brachial artery pseudoaneurysm after phlebotomy for iron overload: first case report (2013) (0)
- [Iron overload of the liver and protein synthesis. Progress made through experimental models]. (1987) (0)
- [Horton's disease and hepatic involvement simulating secondary cancer of the liver]. (1982) (0)
- [Demonstration by iron overloading study and HLA genotyping of recessive transmission of idiopathic haemochromatosis in two pseudodominant pedigrees (author's transl)]. (1979) (0)
- Therapeutic recommendations in HFE haemochromatosis (2017) (0)
- Phlebotomy in medicine:a very long story that is not over yet (2017) (0)
- [Report of a new case of purpura due to an IgA (K) - IgG cryoglobulinemia (author's transl)]. (1979) (0)
- 413 LONG-TERM DEFERASIROX THERAPY IS ASSOCIATED WITH STABILIZATION OR IMPROVEMENT OF LIVER FIBROSIS AND NECROINFLAMMATION IN PATIENTS WITH ß-THALASSEMIA REGARDLESS OF HEPATITIS C STATUS (2011) (0)
- Physiopathologie et classification des hémochromatoses (1977) (0)
- [Diagnostic strategy for iron overload in adults (excluding hematologic iron overload)]. (2000) (0)
- Valproic Acid Induces Hepcidin Expression (2016) (0)
- Subject Index, Vol. 17, 1978 (1978) (0)
- Évaluation non invasive de la fibrose hépatique par mesure de l'élastométrie du foie chez 15 patients avec surcharge en fer post-transfusionnelle (2006) (0)
- [Physiopathology and classification of hemochromatosis]. (1977) (0)
- gene discovery: revisiting the diagnostic strategy (1998) (0)
- [Molecular genetics of hemochromatosis]. (1999) (0)
- Mouse genetic background impacts both on iron and non-iron metals parameters and on their relationships (2015) (0)
- Iron Overload: Diagnosis, Complications, and Management (2016) (0)
- Selected abstracts. Meeting of the French Association for the Study of the Liver. Nice, France, 10-11 March 1986. (1986) (0)
- [Genetics and physiopathology of hemochromatosis]. (2000) (0)
- Comparative Effect of the Oral Iron Chelators ICL670A and CP20 on Cell Proliferation, Apoptosis and Polyamine Metabolism in Rat and Human Liver Cell Cultures. (2005) (0)
- [Current data on iron overload]. (1990) (0)
- Altered Hepcidin Regulation in Hereditary Hemochromatosis and Dysmetabolic Hyperferritinemia. (2005) (0)
- [Primary sclerosing cholangitis]. (1990) (0)
- [Biology and genetics of iron metabolism abnormalities. 7th Joint Meeting Inserm-SFBC. Paris, 27 November 1997]. (1998) (0)
- Ultrastructural features of experimental liver iron overload in primates (1984) (0)
- [Diagnosis of idiopathic hemochromatosis in 1981]. (1981) (0)
- Iconography : Genetic hemochromatosis: Pathophysiology, diagnostic and therapeutic management (2017) (0)
- Genetical diagnosis of hemochromatosis (2004) (0)
- Haemochromatosis revisited (2022) (0)
- [Analysis of the activities (1985-1991) of the doctoral thesis "Cellular and Functional Biology of Digestion"]. (1991) (0)
- [Iron metabolism: new genes for historical diseases]. (2002) (0)
- How should unexplained chronic anicteric cholestasis be investigated (1998) (0)
- [Practical management of HFE hemochromatosis]. (2006) (0)
- [Etiologic diagnosis of febrile nodular panniculitis. Value of serum protein electrophoresis proteins]. (1980) (0)
- [Diagnosis and treatment of genetic hemochromatosis]. (2000) (0)
- 362 Molecular mechanisms of hepatic iron accumulation induced by oxidative stress in HUH7 human hepatoma cell lines (2006) (0)
- 561 Reversibility of hepatic fibrosis in treated genetic haemochromatosis — A study of 28 cases (2004) (0)
- Short-term prednisolone followed by recombinant human alpha-interferon alone or combined with adenine-arabinoside: A prospective and randomized trial. Preliminary results (1990) (0)
- [Hematochromatosis: serious but not well known]. (1994) (0)
- [The diagnosis of hemochromatosis in the era of the gene]. (1999) (0)
- [Hepatic involvement in Horton's disease]. (1978) (0)
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What Schools Are Affiliated With Prof. P. Brissot?
Prof. P. Brissot is affiliated with the following schools:
