Pierre Charneau | Academic Influence

Pierre Charneau's AcademicInfluence.com Rankings

Pierre Charneau

Computer Science

#11374

World Rank

#12045

Historical Rank

Algorithms

#467

World Rank

#473

Historical Rank

Machine Learning

#5206

World Rank

#5272

Historical Rank

Artificial Intelligence

#5614

World Rank

#5696

Historical Rank

computer-science Degrees

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Computer Science

Pierre Charneau's Degrees

PhD Computer Science Université Paris Cité
Bachelors Mathematics Université Paris Cité

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Why Is Pierre Charneau Influential?

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According to Wikipedia, Pierre Charneau is a French virologist, inventor, and head of the Molecular Virology and Vaccinology Unit at the Pasteur Institute and an acknowledged specialist in HIV, lentiviral gene transfer vectors, and their medical applications. His discovery of the central DNA-flap structure in the HIV genome, and its role in viral entry into the nucleus of the infected cell, grounded the optimization of lentiviral vectors and allowed for more than 20 years of development in gene therapy and vaccines based on this gene delivery technology. Charneau has published more than 100 research articles and holds 25 patents in the field of HIV and lentiviral vectors.

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Pierre Charneau's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Blood‐brain barrier‐specific properties of a human adult brain endothelial cell line (2005) (1189)
HIV-1 Genome Nuclear Import Is Mediated by a Central DNA Flap (2000) (894)
IgA dominates the early neutralizing antibody response to SARS-CoV-2 (2020) (734)
HIV-1 reverse transcription. A termination step at the center of the genome. (1994) (406)
Ex vivo expansion of human hematopoietic stem cells by direct delivery of the HOXB4 homeoprotein (2003) (316)
A second origin of DNA plus-strand synthesis is required for optimal human immunodeficiency virus replication (1992) (304)
HIV‐1 DNA Flap formation promotes uncoating of the pre‐integration complex at the nuclear pore (2007) (291)
Quantitative four-dimensional tracking of cytoplasmic and nuclear HIV-1 complexes (2006) (278)
The human immunodeficiency virus type-1 central DNA flap is a crucial determinant for lentiviral vector nuclear import and gene transduction of human hematopoietic stem cells. (2000) (238)
Secreted dengue virus nonstructural protein NS1 is an atypical barrel-shaped high-density lipoprotein (2011) (222)
The HIV-1 DNA flap stimulates HIV vector-mediated cell transduction in the brain (2001) (212)
A comparison of four serological assays for detecting anti–SARS-CoV-2 antibodies in human serum samples from different populations (2020) (205)
Isolation and envelope sequence of a highly divergent HIV-1 isolate: definition of a new HIV-1 group. (1994) (181)
Activity-Dependent Adjustments of the Inhibitory Network in the Olfactory Bulb following Early Postnatal Deprivation (2005) (176)
Enhanced transgene expression in cord blood CD34(+)-derived hematopoietic cells, including developing T cells and NOD/SCID mouse repopulating cells, following transduction with modified trip lentiviral vectors. (2001) (170)
Human immunodeficiency virus type 1 Vif- mutant particles from restrictive cells: role of Vif in correct particle assembly and infectivity (1995) (165)
Fusion from without directed by human immunodeficiency virus particles (1994) (157)
Complementation of murine cells for human immunodeficiency virus envelope/CD4-mediated fusion in human/murine heterokaryons (1992) (154)
Role for DNA repair factor XRCC4 in immunoglobulin class switch recombination (2007) (153)
A single-stranded gap in human immunodeficiency virus unintegrated linear DNA defined by a central copy of the polypurine tract (1991) (152)
Human Nucleoporins Promote HIV-1 Docking at the Nuclear Pore, Nuclear Import and Integration (2012) (150)
Superresolution imaging of HIV in infected cells with FlAsH-PALM (2012) (144)
Accessibility of nuclear DNA to triplex-forming oligonucleotides: the integrated HIV-1 provirus as a target. (1997) (137)
Nup153 and Nup98 bind the HIV-1 core and contribute to the early steps of HIV-1 replication (2013) (137)
Turning Astrocytes from the Rostral Migratory Stream into Neurons: A Role for the Olfactory Sensory Organ (2008) (127)
IL-7 differentially regulates cell cycle progression and HIV-1-based vector infection in neonatal and adult CD4+ T cells (2001) (125)
A Single Injection of Recombinant Measles Virus Vaccines Expressing Human Immunodeficiency Virus (HIV) Type 1 Clade B Envelope Glycoproteins Induces Neutralizing Antibodies and Cellular Immune Responses to HIV (2004) (125)
Liver Cancer-Derived Hepatitis C Virus Core Proteins Shift TGF-Beta Responses from Tumor Suppression to Epithelial-Mesenchymal Transition (2009) (125)
The phosphorylation of the androgen receptor by TFIIH directs the ubiquitin/proteasome process (2011) (119)
Serologic responses to SARS-CoV-2 infection among hospital staff with mild disease in eastern France (2020) (119)
Bipotential mouse embryonic liver stem cell lines contribute to liver regeneration and differentiate as bile ducts and hepatocytes. (2004) (119)
Transcriptional Activation of Interleukin-8 by β-Catenin-Tcf4* (2002) (116)
Chromatin organization at the nuclear pore favours HIV replication (2015) (110)
The Maturation of Dendritic Cells Results in Postintegration Inhibition of HIV-1 Replication1 (2001) (108)
Lentivirus-mediated gene transfer in primary T cells is enhanced by a central DNA flap (2001) (104)
Human T-cell lymphotropic virus oncoprotein Tax represses TGF-beta 1 signaling in human T cells via c-Jun activation: a potential mechanism of HTLV-I leukemogenesis. (2002) (103)
Inactivation of hTERT transcription by Tax (2003) (91)
The Structure of HIV-1 Genomic RNA in the gp120 Gene Determines a Recombination Hot Spot in Vivo* (2004) (85)
Intranasal vaccination with a lentiviral vector protects against SARS-CoV-2 in preclinical animal models (2020) (85)
SARS-CoV-2 infection in primary schools in northern France: A retrospective cohort study in an area of high transmission (2020) (84)
A single immunization with a minute dose of a lentiviral vector‐based vaccine is highly effective at eliciting protective humoral immunity against West Nile virus (2006) (81)
G Protein-Dependent CCR5 Signaling Is Not Required for Efficient Infection of Primary T Lymphocytes and Macrophages by R5 Human Immunodeficiency Virus Type 1 Isolates (2003) (79)
Plasticity of Hepatic Cell Differentiation: Bipotential Adult Mouse Liver Clonal Cell Lines Competent to Differentiate In Vitro and In Vivo (2006) (79)
Use of a lentiviral flap vector for induction of CTL immunity against melanoma. Perspectives for immunotherapy (2002) (78)
SARS-CoV-2 serological analysis of COVID-19 hospitalized patients, pauci-symptomatic individuals and blood donors. (2020) (78)
Protective Antiviral Immunity Conferred by a Nonintegrative Lentiviral Vector-Based Vaccine (2008) (77)
Kinetic analysis of HIV-1 early replicative steps in a coculture system. (1994) (74)
Transcriptional activation of interleukin-8 by beta-catenin-Tcf4. (2002) (73)
Microtubule-associated Proteins 1 (MAP1) Promote Human Immunodeficiency Virus Type I (HIV-1) Intracytoplasmic Routing to the Nucleus (2014) (61)
Lentiviral vectors encoding HIV-1 polyepitopes induce broad CTL responses in vivo. (2007) (60)
Lentiviral Vector-Based Prime/Boost Vaccination against AIDS: Pilot Study Shows Protection against Simian Immunodeficiency Virus SIVmac251 Challenge in Macaques (2009) (59)
Transduced CD34+ cells from adrenoleukodystrophy patients with HIV-derived vector mediate long-term engraftment of NOD/SCID mice. (2003) (58)
Stable and functional lymphoid reconstitution in artemis-deficient mice following lentiviral artemis gene transfer into hematopoietic stem cells. (2008) (58)
Prevalence of SARS-CoV-2 antibodies in France: results from nationwide serological surveillance (2020) (57)
Asymptomatic and symptomatic SARS-CoV-2 infections elicit polyfunctional antibodies (2020) (56)
A highly efficient, stable, and rapid approach for ex vivo human liver gene therapy via a FLAP lentiviral vector (2003) (55)
High seroprevalence but short‐lived immune response to SARS‐CoV‐2 infection in Paris (2020) (53)
A highly defective HIV-1 group O provirus: evidence for the role of local sequence determinants in G-->A hypermutation during negative-strand viral DNA synthesis. (1995) (53)
Direct recognition by alphabeta cytolytic T cells of Hfe, a MHC class Ib molecule without antigen-presenting function. (2005) (50)
Immunogenic HLA-B*0702-Restricted Epitopes Derived from Human Telomerase Reverse Transcriptase That Elicit Antitumor Cytotoxic T-Cell Responses (2006) (48)
SARS-CoV-2 infection in schools in a northern French city: a retrospective serological cohort study in an area of high transmission, France, January to April 2020 (2021) (47)
BM88/Cend1 Expression Levels Are Critical for Proliferation and Differentiation of Subventricular Zone‐Derived Neural Precursor Cells (2008) (45)
Antibodies to several conformation-dependent epitopes of gp120/gp41 inhibit CCR-5-dependent cell-to-cell fusion mediated by the native envelope glycoprotein of a primary macrophage-tropic HIV-1 isolate. (1997) (45)
Long-Term Expression of β-Glucuronidase by Genetically Modified Human Neural Progenitor Cells Grafted into the Mouse Central Nervous System (2002) (45)
Remodeling of the Core Leads HIV-1 Preintegration Complex into the Nucleus of Human Lymphocytes (2020) (43)
Effects of the Tat basic domain on human immunodeficiency virus type 1 transactivation, using chemically synthesized Tat protein and Tat peptides (1994) (43)
Restoration of human B-cell differentiation into NOD-SCID mice engrafted with gene-corrected CD34+ cells isolated from Artemis or RAG1-deficient patients. (2008) (41)
In vivo imaging of migrating neurons in the mammalian forebrain. (2005) (41)
Reprogrammed quiescent B cells provide an effective cellular therapy against chronic experimental autoimmune encephalomyelitis (2011) (40)
Histopathological and cognitive defects induced by Nef in the brain (2004) (37)
BNT162b2 vaccine-induced humoral and cellular responses against SARS-CoV-2 variants in systemic lupus erythematosus (2021) (37)
A Nonintegrative Lentiviral Vector-Based Vaccine Provides Long-Term Sterile Protection against Malaria (2012) (35)
Nuclear Import Defect of Human Immunodeficiency Virus Type 1 DNA Flap Mutants Is Not Dependent on the Viral Strain or Target Cell Type (2006) (35)
HIV-derived vectors for therapy and vaccination against HIV. (2012) (35)
Wild-type and central DNA flap defective HIV-1 lentiviral vector genomes: intracellular visualization at ultrastructural resolution levels (2006) (34)
Targeting human telomerase reverse transcriptase with recombinant lentivector is highly effective to stimulate antitumor CD8 T-cell immunity in vivo. (2010) (32)
Predominance of CCR5-dependent HIV-1 subtype E isolates in Cambodia. (1999) (32)
Transplantation of Embryonic Neural Stem/Precursor Cells Overexpressing BM88/Cend1 Enhances the Generation of Neuronal Cells in the Injured Mouse Cortex (2009) (32)
A haplotype of the human CXCR1 gene protective against rapid disease progression in HIV-1+ patients (2007) (32)
Protective role of LGP2 in influenza virus pathogenesis. (2014) (29)
Humoral immunity to SARS-CoV-2 and seasonal coronaviruses in children and adults in north-eastern France (2021) (29)
CrAsH-quantum dot nanohybrids for smart targeting of proteins. (2008) (26)
Multiplexed Quantitation of Intraphagocyte Mycobacterium tuberculosis Secreted Protein Effectors (2018) (25)
A Japanese Encephalitis Virus Vaccine Inducing Antibodies Strongly Enhancing In Vitro Infection Is Protective in Pigs (2017) (22)
A Lentiviral Vector Expressing Japanese Encephalitis Virus-like Particles Elicits Broad Neutralizing Antibody Response in Pigs (2015) (22)
Brain engraftment of autologous macrophages transduced with a lentiviral flap vector: an approach to complement brain dysfunctions (2002) (21)
Use of a lentiviral vector encoding a HCMV-chimeric IE1-pp65 protein for epitope identification in HLA-Transgenic mice and for ex vivo stimulation and expansion of CD8(+) cytotoxic T cells from human peripheral blood cells. (2004) (21)
Heterologous viral RNA export elements improve expression of severe acute respiratory syndrome (SARS) coronavirus spike protein and protective efficacy of DNA vaccines against SARS (2007) (20)
TOX4 and NOVA1 Proteins Are Partners of the LEDGF PWWP Domain and Affect HIV-1 Replication (2013) (20)
Interclade neutralization and enhancement of human immunodeficiency virus type 1 identified by an assay using HeLa cells expressing both CD4 receptor and CXCR4/CCR5 coreceptors. (2004) (20)
Transplantation of human adult astrocytes: Efficiency and safety requirements for an autologous gene therapy (2003) (20)
A Single Dose of NILV-Based Vaccine Provides Rapid and Durable Protection against Zika Virus (2020) (19)
Brain cross‐protection against SARS‐CoV‐2 variants by a lentiviral vaccine in new transgenic mice (2021) (18)
Alternative splicing‐regulated protein of hepatitis B virus hacks the TNF‐α‐stimulated signaling pathways and limits the extent of liver inflammation (2015) (18)
Residual HIV-1 DNA Flap-independent nuclear import of cPPT/CTS double mutant viruses does not support spreading infection (2011) (17)
Potent human broadly SARS-CoV-2–neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2 (2022) (16)
Variable correction of Artemis deficiency by I-Sce1-meganuclease-assisted homologous recombination in murine hematopoietic stem cells (2014) (15)
A hepatitis C virus (HCV) NS3/4A protease-dependent strategy for the identification and purification of HCV-infected cells. (2006) (14)
Lack of endogenous TRIM5alpha-mediated restriction in rhesus macaque dendritic cells. (2008) (14)
Lentiviral vector induces high-quality memory T cells via dendritic cells transduction (2021) (14)
Efficient transfer of HTLV-1 tax gene in various primary and immortalized cells using a flap lentiviral vector. (2002) (13)
Immunogenicity of a recombinant lentiviral vector carrying human telomerase tumor antigen in HLA-B*0702 transgenic mice. (2010) (12)
An intranasal lentiviral booster reinforces the waning mRNA vaccine-induced SARS-CoV-2 immunity that it targets to lung mucosa (2022) (12)
Pre-COVID-19 humoral immunity to common coronaviruses does not confer cross-protection against SARS-CoV-2 (2020) (12)
Use of lentiviral vectors in vaccination (2021) (11)
BNT 162 b 2 vaccine-induced humoral and cellular responses against SARS-CoV-2 variants in systemic lupus erythematosus (2021) (10)
Lower disease activity but higher risk of severe COVID-19 and herpes zoster in patients with systemic lupus erythematosus with pre-existing autoantibodies neutralising IFN-α (2022) (10)
A SecondOrigin ofDNA Plus-Strand Synthesis IsRequired for Optimal HumanImmunodeficiency VirusReplication (1992) (10)
Remodeling of the core leads HIV-1 pre-integration complex in the nucleus of human lymphocytes (2020) (10)
High seroprevalence of SARS-CoV-2 antibodies among people living in precarious situations in Ile de France (2020) (8)
Recombinant Zika NS1 Protein Secreted from Vero Cells Is Efficient for Inducing Production of Immune Serum Directed against NS1 Dimer (2017) (6)
Intranasal Vaccination with a Lentiviral Vector Strongly Protects against SARS-CoV-2 in Mouse and Golden Hamster Preclinical Models (2020) (6)
Bisarsenical labeling of HIV-1 for real-time fluorescence microscopy. (2009) (5)
Pre-COVID-19 Immunity to Common Cold Human Coronaviruses Induces a Recall-Type IgG Response to SARS-CoV-2 Antigens Without Cross-Neutralisation (2022) (5)
A lentiviral vector encoding fusion of light invariant chain and mycobacterial antigens induces protective CD4+ T cell immunity. (2022) (4)
A Humanized Mouse Strain That Develops Spontaneously Immune-Mediated Diabetes (2021) (3)
Full Brain and Lung Prophylaxis against SARS-CoV-2 by Intranasal Lentiviral Vaccination in a New hACE2 Transgenic Mouse Model or Golden Hamsters (2021) (3)
Fusion fromWithout Directed byHumanImmunodeficiency VirusParticles (1994) (2)
sgDI-tector: defective interfering viral genome bioinformatics for detection of coronavirus subgenomic RNAs (2021) (2)
Recombinant Zika NS 1 Protein Secreted from Vero Cells Is Efficient for Inducing Production of Immune Serum Directed against NS 1 Dimer (2018) (2)
[Observation of the HIV-1 virus in infected cells using microscopy approaches]. (2008) (2)
Full-Lung Prophylaxis against SARS-CoV-2 by One-Shot or Booster Intranasal Lentiviral Vaccination in Syrian Golden Hamsters (2022) (1)
Nup153 and Nup98 bind the HIV-1 core and contribute to the early steps of HIV-1 replication (2013) (1)
A lentiviral vector expressing a dendritic cell-targeting multimer induces mucosal anti-mycobacterial CD4+ T-cell immunity (2022) (1)
Promoter’s Choice Drive CAR-T Efficiency (2021) (1)
Brain and Lung Cross-Protection against Ancestral or Emerging SARS-CoV-2 by Intranasal Lentiviral Vaccination in a New hACE2 Transgenic Murine Model (2021) (1)
Chantal Immune Responses to HIV Neutralizing Antibodies and Cellular B Envelope Glycoproteins Induces Immunodeficiency Virus ( HIV ) Type 1 Clade Virus Vaccines Expressing Human A Single Injection of Recombinant Measles (2003) (1)
Intranasal Immunization with a Lentiviral Vector Coding for SARS-CoV-2 Spike Protein Confers Vigorous Protection in Pre-Clinical Animal Models (2020) (1)
Rapid ex vivo protocol for efficient and stable gene transfer in the liver via hepatocyte transduction by flap lentiviral vectors (2003) (0)
An intranasal lentiviral booster broadens immune recognition of SARS-CoV-2 variants and reinforces the waning mRNA vaccine-induced immunity that it targets to lung mucosa (2022) (0)
HIV-1 capsid interacts with cytoskeletal-associated proteins for intracytoplasmic routing to the nucleus (2013) (0)
Recombinant Zika NS 1 protein secreted from Vero cells is efficient for inducing production of immune serum against NS 1 dimer (2018) (0)
Use of proteins and peptides encoded by the genome of a new strain of coronavirus associated with SARS (2004) (0)
Defective lentiviral transfer vectors that do not integrate vaccine (2007) (0)
Restoration of B Cell Development after Lentiviral Transduction of CD34+ Hematopoietic Cells from RAG-1 Deficient Patient. (2004) (0)
DNA triple hÃ © lice lentiviral vectors, and vectors and recombinant cells CA © containing DNA triple hÃ © lice lentiviral (2000) (0)
Cells and methodology to generate nonsegmented negative sense strand RNA viruses (2006) (0)
[Intracellular vizualization of the HIV1 genome using in situ hybridization and electron microscopy]. (2007) (0)
Mice Humanized for Major Histocompatibility Complex and Angiotensin-Converting Enzyme 2 with High Permissiveness to SARS-CoV-2 Omicron Replication (2022) (0)
Vectors for the preparation of immunotherapeutic compositions (1999) (0)
Nucleotide sequences of retroviral antigens HIV-1 group (or subgroup) or. (1995) (0)
Nucleotide sequences encoding antigens of a retrovirus of the HIV-1 group type o (1994) (0)
Lentiviral triplex DNA, and vectors and recombinant cells containing DNA triple helix lentiviral. (2000) (0)
Use of DNA sequences of the triplex structure for nucleotide sequences tranfer into cells, recombinant vectors containing these sequences triplex (1998) (0)
Using lentivirus sequences triple structure for nuclear import of nucleotide sequences (1999) (0)
Lentiviral vector recombinant expression of a protein of Flaviviridae and its application as a vaccine (2004) (0)
Using DNA sequences triple structure for the transfer of nucleotide sequences (1999) (0)
P17-20. Lentiviral vector-based vaccine against SIV infection and simian AIDS (2009) (0)
Lentiviral Vectors as a Vaccine Platform against Infectious Diseases (2023) (0)
ReplicationPostintegration Inhibition of HIV-1 The Maturation of Dendritic Cells Results in (2001) (0)
Use of triplex structure-DNA sequences for the transfer of nucleotide sequences (1999) (0)
Lentiviral vector induces high-quality memory T cells via dendritic cells transduction (2021) (0)
Nucleotides sequences of retroviral antigenic HIV-I group (or subgroup) o (1995) (0)
Remodeling of the core leads HIV-1 pre-integration complex into the nucleus of human lymphocytes (2019) (0)
HIV-1 capsid interacts with cytoskeletal-associated proteins for intracytoplasmic routing to the nucleus (2013) (0)
New connected to sars coronavirus originated and its uses (2004) (0)
In the vaccine based lentiviral vector (2006) (0)
Recombinant Zika NS1 protein secreted from Vero cells is efficient for inducing production of immune serum against NS1 dimer (2019) (0)
423 HCV CORE TUMOR VARIANTS SHIFT TGF-BETA RESPONSES FROM TUMOR SUPPRESSION TO ONCOGENESIS IN PRIMARY HUMAN AND MOUSE HEPATOCYTES (2008) (0)
containing lentiviral triplex DNA, and vectors and recombinant cells, lentiviral triplex-dns (2000) (0)
Mice Humanized for MHC and hACE2 with High Permissiveness to SARS-CoV-2 Omicron Replication (2023) (0)
Correction: Human Nucleoporins Promote HIV-1 Docking at the Nuclear Pore, Nuclear Import and Integration (2013) (0)
Functional screening of antigenic polypeptides - use for the identification of antigens eliciting a protective immune response and for the selection of antigens with optimal protective activity (2017) (0)
P.045 The hepatitis B virus x protein up-regulates gamma aminobutyric acid type A β3 receptor expression (2006) (0)
lentiviral vectors for the preparation of immunotherapeutic compositions. (2000) (0)

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