Piet Borst

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Piet Borst is affiliated with the following schools: University of Amsterdam, University of Groningen, Leiden University

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Piet Borst

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Philosophy

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PhD Medicine University of Amsterdam

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Piet Borst's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs (1994) (2237)
A family of drug transporters: the multidrug resistance-associated proteins. (2000) (1715)
Mammalian ABC transporters in health and disease. (2002) (1542)
Homozygous disruption of the murine MDR2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease (1993) (1383)
Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A. (1995) (1151)
Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins. (1997) (971)
Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines. (1997) (935)
Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine. (1997) (898)
High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs (2008) (874)
MDR1 P-Glycoprotein Is a Lipid Translocase of Broad Specificity, While MDR3 P-Glycoprotein Specifically Translocates Phosphatidylcholine (1996) (864)
Congenital Jaundice in Rats with a Mutation in a Multidrug Resistance-Associated Protein Gene (1996) (854)
The multidrug resistance protein family. (1999) (664)
Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA. (1998) (639)
MRP3, an organic anion transporter able to transport anti-cancer drugs. (1999) (636)
Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport. (1994) (633)
Localization of nine glycolytic enzymes in a microbody‐like organelle in Trypanosoma brucei: The glycosome (1977) (590)
A mutation in the human canalicular multispecific organic anion transporter gene causes the Dubin‐Johnson syndrome (1997) (529)
The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs (2003) (525)
Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein. (1995) (499)
Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs. (2000) (478)
REV7 counteracts DNA double-strand break resection and affects PARP inhibition (2015) (478)
Antifolate resistance mediated by the multidrug resistance proteins MRP1 and MRP2. (1999) (461)
Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein (1997) (440)
Loss of 53BP1 causes PARP inhibitor resistance in Brca1-mutated mouse mammary tumors. (2013) (428)
A freeze-squeeze method for recovering long DNA from agarose gels. (1975) (427)
The gel electrophoresis of DNA. (1972) (421)
Characterization of the transport of nucleoside analog drugs by the human multidrug resistance proteins MRP4 and MRP5. (2003) (384)
Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier. (2000) (356)
Molecular basis for trypanosome antigenic variation (1982) (326)
Interactions of the human multidrug resistance proteins MRP1 and MRP2 with organic anions. (2000) (325)
Expression of human MRP6, a homologue of the multidrug resistance protein gene MRP1, in tissues and cancer cells. (1999) (321)
Discontinuous transcription and antigenic variation in trypanosomes. (1986) (318)
Antigenic variation in trypanosoma brucei analyzed by electrophoretic separation of chromosome-sized DNA molecules (1984) (316)
Severe plasmalogen deficiency in tissues of infants without peroxisomes (Zellweger syndrome) (1983) (315)
ABC transporters in lipid transport. (2000) (314)
Steroid and bile acid conjugates are substrates of human multidrug-resistance protein (MRP) 4 (ATP-binding cassette C4). (2003) (305)
Substantial excretion of digoxin via the intestinal mucosa and prevention of long‐term digoxin accumulation in the brain by the mdrla P‐glycoprotein (1996) (304)
Uncoupling activity of long-chain fatty acids. (1962) (302)
Selective induction of chemotherapy resistance of mammary tumors in a conditional mouse model for hereditary breast cancer (2007) (301)
The mitochondrial genome of yeast (1978) (301)
A new method for fluorescence microscopical localization of specific DNA sequences by in situ hybridization of fluorochromelabelled RNA. (1980) (298)
Multidrug resistance-associated proteins 3, 4, and 5 (2007) (296)
Functional Multidrug Resistance Protein (MRP1) Lacking the N-terminal Transmembrane Domain* (1998) (296)
Full blockade of intestinal P-glycoprotein and extensive inhibition of blood-brain barrier P-glycoprotein by oral treatment of mice with PSC833. (1997) (284)
Basolateral localization and export activity of the human multidrug resistance-associated protein in polarized pig kidney cells. (1996) (280)
The human mdr3 gene encodes a novel P‐glycoprotein homologue and gives rise to alternatively spliced mRNAs in liver. (1987) (278)
Sequence of mdr3 cDNA encoding a human P-glycoprotein. (1988) (275)
The human MDR3 P‐glycoprotein promotes translocation of phosphatidylcholine through the plasma membrane of fibroblasts from transgenic mice (1994) (275)
Characterization of the MRP4- and MRP5-mediated Transport of Cyclic Nucleotides from Intact Cells* (2003) (270)
New mechanisms of drug resistance in parasitic protozoa. (1995) (267)
Programmed gene rearrangements altering gene expression. (1987) (263)
Inactivation of transcription by UV irradiation of T. brucei provides evidence for a multicistronic transcription unit including a VSG gene (1987) (262)
Tissue Distribution and Induction of Human Multidrug Resistant Protein 3 (2002) (261)
MDR3 P-glycoprotein, a Phosphatidylcholine Translocase, Transports Several Cytotoxic Drugs and Directly Interacts with Drugs as Judged by Interference with Nucleotide Trapping* (2000) (254)
Canalicular multispecific organic anion transporter/multidrug resistance protein 2 mediates low-affinity transport of reduced glutathione. (1999) (248)
Overexpression and amplification of five genes in a multidrug-resistant Chinese hamster ovary cell line (1986) (242)
Vinblastine and sulfinpyrazone export by the multidrug resistance protein MRP2 is associated with glutathione export (2000) (239)
Specific detection of multidrug resistance proteins MRP1, MRP2, MRP3, MRP5, and MDR3 P-glycoprotein with a panel of monoclonal antibodies. (2000) (233)
Interactions between Hepatic Mrp4 and Sult2a as Revealed by the Constitutive Androstane Receptor and Mrp4 Knockout Mice* (2004) (231)
The amplified H circle of methotrexate‐resistant leishmania tarentolae contains a novel P‐glycoprotein gene. (1990) (230)
An analysis of cosmid clones of nuclear DNA from Trypanosoma brucei shows that the genes for variant surface glycoproteins are clustered in the genome. (1982) (230)
ABCC6–Mediated ATP Secretion by the Liver Is the Main Source of the Mineralization Inhibitor Inorganic Pyrophosphate in the Systemic Circulation—Brief Report (2014) (229)
Mechanism of the Pharmacokinetic Interaction between Methotrexate and Benzimidazoles (2004) (227)
Inhibitory effect of the reversal agents V-104, GF120918 and Pluronic L61 on MDR1 Pgp-, MRP1- and MRP2-mediated transport (2000) (216)
Characterization of the human MDR3 P-glycoprotein and its recognition by P-glycoprotein-specific monoclonal antibodies. (1991) (215)
Growth of chromosome ends in multiplying trypanosomes (1983) (214)
Multidrug Resistance Protein 1 Protects the Oropharyngeal Mucosal Layer and the Testicular Tubules against Drug-induced Damage (1998) (208)
ABCC6 prevents ectopic mineralization seen in pseudoxanthoma elasticum by inducing cellular nucleotide release (2013) (208)
How do real tumors become resistant to cisplatin? (2008) (205)
Activation of trypanosome surface glycoprotein genes involves a duplication-transposition leading to an altered 3′ end (1981) (204)
Evidence for Two Interacting Ligand Binding Sites in Human Multidrug Resistance Protein 2 (ATP Binding Cassette C2)* (2003) (203)
Mice lacking multidrug resistance protein 3 show altered morphine pharmacokinetics and morphine-6-glucuronide antinociception. (2005) (203)
Novel expression-linked copies of the genes for variant surface antigens in trypanosomes (1980) (202)
Enhanced oral bioavailability of paclitaxel in mice treated with the P-glycoprotein blocker SDZ PSC 833. (1997) (200)
Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality. (2018) (199)
Multidrug resistance and the role of P-glycoprotein knockout mice. (1995) (199)
Subunit composition of VRAC channels determines substrate specificity and cellular resistance to Pt‐based anti‐cancer drugs (2015) (197)
Three small RNAs within the 10 kb trypanosome rRNA transcription unit are analogous to domain VII of other eukaryotic 28S rRNAs. (1986) (196)
Mitochondrial DNA: V. A 25-μ closed circular duplex DNA molecule in wild-type yeast mitochondria. Structure and genetic complexity (1970) (196)
The promoter for a variant surface glycoprotein gene expression site in Trypanosoma brucei. (1990) (192)
Alpha-amanitin-insensitive transcription of variant surface glycoprotein genes provides further evidence for discontinuous transcription in trypanosomes. (1984) (190)
Thiopurine metabolism and identification of the thiopurine metabolites transported by MRP4 and MRP5 overexpressed in human embryonic kidney cells. (2002) (190)
Some yeast mitochondrial RNAs are circular (1980) (189)
Peroxisome biogenesis revisited. (1989) (188)
Classical and novel forms of multidrug resistance and the physiological functions of P-glycoproteins in mammals. (1993) (187)
Cancer drug pan-resistance: pumps, cancer stem cells, quiescence, epithelial to mesenchymal transition, blocked cell death pathways, persisters or what? (2012) (184)
Antigenic Variation and Allelic Exclusion (2002) (183)
Altered pharmacokinetics of vinblastine in Mdr1a P-glycoprotein-deficient Mice. (1996) (181)
Structure of the growing telomeres of trypanosomes (1984) (181)
The human multidrug resistance-associated protein functionally complements the yeast cadmium resistance factor 1. (1996) (174)
Genes amplified and overexpressed in human multidrug-resistant cell lines. (1988) (173)
Mice lacking Mrp3 (Abcc3) have normal bile salt transport, but altered hepatic transport of endogenous glucuronides. (2006) (172)
Tissue distribution of the human MDR3 P-glycoprotein. (1994) (171)
Base J: discovery, biosynthesis, and possible functions. (2008) (168)
β-d-glucosyl-hydroxymethyluracil: A novel modified base present in the DNA of the parasitic protozoan T. brucei (1993) (165)
The anatomy and transcription of a telomeric expression site for variant-specific surface antigens in T. brucei (1987) (165)
The role of transferrin-receptor variation in the host range of Trypanosoma brucei (1998) (162)
Targeted insertion of the neomycin phosphotransferase gene into the tubulin gene cluster of Trypanosoma brucei (1990) (160)
Mitochondrial DNA: physicochemical properties, replication, and genetic function. (1969) (156)
Hepatic secretion of phospholipid vesicles in the mouse critically depends on mdr2 or MDR3 P-glycoprotein expression. Visualization by electron microscopy. (1997) (154)
Direct and inverted DNA repeats associated with P‐glycoprotein gene amplification in drug resistant Leishmania. (1991) (154)
Genomic environment of the expression-linked extra copies of genes for surface antigens of Trypanosoma brucei resembles the end of a chromosome (1982) (151)
Kinetoplast DNA of Trypanosoma evansi. (1987) (150)
On the DNA content and ploidy of trypanosomes. (1982) (149)
Topogenesis of microbody enzymes: a sequence comparison of the genes for the glycosomal (microbody) and cytosolic phosphoglycerate kinases of Trypanosoma brucei. (1985) (142)
A ribosomal DNA promoter replacing the promoter of a telomeric VSG gene expression site can be efficiently switched on and off in T. brucei (1995) (141)
Glucosylated Hydroxymethyluracil, DNA Base J, Prevents Transcriptional Readthrough in Leishmania (2012) (141)
Control of VSG gene expression sites. (2001) (141)
A 22‐kd protein (sorcin/V19) encoded by an amplified gene in multidrug‐resistant cells, is homologous to the calcium‐binding light chain of calpain. (1986) (139)
Antigenic variation in malaria (1995) (136)
Characterization of the DNA duplication-transposition that controls the expression of two genes for variant surface glycoproteins in Trypanosoma brucei. (1982) (135)
Reconstitution of a surface transferrin binding complex in insect form Trypanosoma brucei. (1994) (134)
How proteins get into microbodies (peroxisomes, glyoxysomes, glycosomes). (1986) (133)
RNA splicing is required to make the messenger RNA for a variant surface antigen in trypanosomes. (1982) (133)
Hepatocyte‐specific expression of the human MDR3P‐glycoprotein gene restores the biliary phosphatidylcholine excretion absent in Mdr2 (−/−) mice (1998) (131)
Gel electrophoresis of RNA under denaturing conditions. (1973) (131)
Transport of glutathione prostaglandin A conjugates by the multidrug resistance protein 1 (1997) (130)
Molecular genetics of antigenic variation. (1991) (129)
Chromosome rearrangements in trypanosoma brucei (1984) (129)
Multidrug resistance phenotype of human BRO melanoma cells transfected with a wild-type human mdr1 complementary DNA. (1990) (127)
An insert in the single gene for the large ribosomal RNA in yeast mitochondrial DNA (1978) (127)
Genetic dissection of the function of mammalian P-glycoproteins. (1997) (125)
Intestinal Breast Cancer Resistance Protein (BCRP)/Bcrp1 and Multidrug Resistance Protein 3 (MRP3)/Mrp3 Are Involved in the Pharmacokinetics of Resveratrol (2009) (124)
HELB Is a Feedback Inhibitor of DNA End Resection. (2016) (123)
Surface receptors and transporters of Trypanosoma brucei. (1998) (123)
Localization of the modified base J in telomeric VSG gene expression sites of Trypanosoma brucei. (1997) (123)
Localization of glycerol-3-phosphate oxidase in the mitochondrion and particulate NAD+-linked glycerol-3-phosphate dehydrogenase in the microbodies of the bloodstream form to Trypanosoma brucei. (1977) (122)
The human multidrug resistance protein MRP5 transports folates and can mediate cellular resistance against antifolates. (2005) (122)
P-glycoprotein ABCB1: a major player in drug handling by mammals. (2013) (118)
Mitochondrial DNA. I. Preparation and properties of mitochondrial DNA from chick liver. (1967) (118)
Multidrug resistance mediated by P-glycoproteins. (1991) (118)
Comparison of the genes coding for the common 5' terminal sequence of messenger RNAs in three trypanosome species. (1984) (116)
Differential amplification and disproportionate expression of five genes in three multidrug-resistant Chinese hamster lung cell lines (1986) (115)
beta-D-glucosyl-hydroxymethyluracil is a conserved DNA modification in kinetoplastid protozoans and is abundant in their telomeres. (1998) (114)
Identification of multidrug resistance protein 1 (MRP1/ABCC1) as a molecular gate for cellular export of cobalamin. (2010) (114)
The transposition unit of variant surface glycoprotein gene 118 of Trypanosoma brucei. Presence of repeated elements at its border and absence of promoter-associated sequences. (1983) (113)
Chromosomes of kinetoplastida. (1984) (112)
Altered disposition of acetaminophen in mice with a disruption of the Mrp3 gene (2005) (110)
Characterization of satellite DNA in Trypanosoma brucei and Trypanosoma cruzi. (1983) (110)
Two tandemly linked identical genes code for the glycosomal glyceraldehyde‐phosphate dehydrogenase in Trypanosoma brucei. (1986) (110)
The architecture of variant surface glycoprotein gene expression sites in Trypanosoma brucei. (2002) (109)
MRP2 and 3 in health and disease. (2006) (109)
Hydrogen transport and transport metabolites (1963) (109)
Post-transcriptional control of the differential expression of phosphoglycerate kinase genes in Trypanosoma brucei. (1988) (107)
Multidrug Resistance Proteins 2 and 3 Provide Alternative Routes for Hepatic Excretion of Morphine-Glucuronides (2007) (106)
REPLICATION OF VIRAL RNA, III. DOUBLE-STRANDED REPLICATIVE FORM OF MSW PHAGE RNA. (1964) (105)
What have we learnt thus far from mice with disrupted P-glycoprotein genes? (1996) (105)
The H circles of Leishmania tarentolae are a unique amplifiable system of oligomeric DNAs associated with drug resistance. (1988) (105)
What Makes Tumors Multidrug Resistant? (2007) (104)
The Effect of Low pH on Breast Cancer Resistance Protein (ABCG2)-Mediated Transport of Methotrexate, 7-Hydroxymethotrexate, Methotrexate Diglutamate, Folic Acid, Mitoxantrone, Topotecan, and Resveratrol in In Vitro Drug Transport Models (2007) (104)
Characterization of the gene for the microbody (glycosomal) triosephosphate isomerase of Trypanosoma brucei. (1986) (103)
Discontinuous synthesis of mRNA in trypanosomes. (1984) (103)
Isolation and characterization of kinetoplast DNA from bloodstream form of Trypanosoma brucei (1978) (103)
Circular mitochondrial DNA. (1966) (103)
Transport of bile acids in multidrug-resistance-protein 3-overexpressing cells co-transfected with the ileal Na+-dependent bile-acid transporter. (2003) (102)
The isolation of plasmids containing DNA complementary to messenger RNA for variant surface glycoproteins of Trypanosoma brucei. (1980) (101)
VSG gene expression site control in insect form Trypanosoma brucei. (1994) (100)
Genetic mechanisms of drug resistance. A review. (1991) (100)
Subcellular compartmentation of glycolytic intermediates in Trypanosoma brucei. (1981) (100)
Tandem repetition of the 5′ mini-exon of variant surface glycoprotein genes: A multiple promoter for VSG gene transcription? (1983) (99)
The pathway of glutamate oxidation by mitochondria isolated from different tissues. (1962) (98)
Common elements on the surface of glycolytic enzymes from Trypanosoma brucei may serve as topogenic signals for import into glycosomes. (1987) (97)
Trypanosomes of subgenus Trypanozoon are diploid for housekeeping genes. (1985) (96)
New approach to screening drugs for activity against African trypanosomes (1977) (96)
The major transcripts of the kinetoplast DNA of Trypanosoma brucei are very small ribosomal RNAs (1983) (95)
Do cMOAT (MRP2), other MRP homologues, and LRP play a role in MDR? (1997) (95)
Moderate increase in Mdr1a/1b expression causes in vivo resistance to doxorubicin in a mouse model for hereditary breast cancer. (2009) (94)
Particle-bound enzymes in the bloodstream form of Trypanosoma brucei. (1977) (93)
Alpha-amanitin-resistant transcription units in trypanosomes: a comparison of promoter sequences for a VSG gene expression site and for the ribosomal RNA genes. (1991) (93)
Gene conversions mediating antigenic variation in Trypanosoma brucei can occur in variant surface glycoprotein expression sites lacking 70-base-pair repeat sequences (1997) (93)
Sensitivity and acquired resistance of BRCA1;p53-deficient mouse mammary tumors to the topoisomerase I inhibitor topotecan. (2010) (92)
BRCA-deficient mouse mammary tumor organoids to study cancer-drug resistance (2017) (92)
Trypanosoma brucei contains two RNA polymerase II largest subunit genes with an altered C-terminal domain (1989) (92)
Two modes of activation of a single surface antigen gene of trypanosoma brucei (1984) (91)
Variant surface glycoproteins of Trypanosoma brucei are synthesised with cleavable hydrophobic sequences at the carboxy and amino termini. (1981) (91)
The topogenic signal of the glycosomal (microbody) phosphoglycerate kinase of Crithidia fasciculata resides in a carboxy‐terminal extension. (1988) (89)
Modification of telomeric DNA in Trypanosoma brucei; a role in antigenic variation? (1984) (89)
Control of VSG gene expression sites in Trypanosoma brucei. (1998) (88)
Antigenic variation in African trypanosomes. (1994) (88)
Drug resistance and P-glycoprotein gene amplification in the protozoan parasite Leishmania. (1991) (87)
The protein that binds to DNA base J in trypanosomatids has features of a thymidine hydroxylase (2007) (87)
Efficient production of functional mRNA mediated by RNA polymerase I in Trypanosoma brucei (1991) (86)
Activation of the genes for variant surface glycoproteins 117 and 118 in Trypanosoma brucei. (1983) (85)
The potential use of inhibitors of glycerol‐3‐phosphate oxidase for chemotherapy of African trypanosomiasis (1976) (83)
Isolation of yeast mitochondrial ribosomes highly active in protein synthesis. (1971) (83)
Expression of Human MRP 6 , a Homologue of the Multidrug Resistance Protein Gene MRP 1 , in Tissues and Cancer Cells 1 (1998) (81)
Subnuclear localization of the active variant surface glycoprotein gene expression site in Trypanosoma brucei. (1998) (81)
Mice Lacking the Multidrug Resistance Protein 1 Are Resistant to Streptococcus pneumoniae-Induced Pneumonia1 (2001) (80)
Contribution of the drug transporter ABCG2 (breast cancer resistance protein) to resistance against anticancer nucleosides (2008) (80)
Characterization of DNA from Trypanosoma brucei and related trypanosomes by restriction endonuclease digestion (1980) (80)
The telomeric GGGTTA repeats of Trypanosoma brucei contain the hypermodified base J in both strands (1996) (79)
Many trypanosome messenger RNAs share a common 5' terminal sequence. (1984) (78)
Mitochondrial antibiotic resistance in yeast: ribosomal mutants resistant to chloramphenicol, erythromycin and spiramycin. (1973) (78)
Role of the N-terminal Transmembrane Region of the Multidrug Resistance Protein MRP2 in Routing to the Apical Membrane in MDCKII Cells* (2002) (77)
The malate–aspartate shuttle (Borst cycle): How it started and developed into a major metabolic pathway (2020) (77)
Does the absence of ABCC6 (Multidrug Resistance Protein 6) in patients with Pseudoxanthoma elasticum prevent the liver from providing sufficient vitamin K to the periphery? (2008) (76)
Mice without phosphatidylcholine transfer protein have no defects in the secretion of phosphatidylcholine into bile or into lung airspaces. (1999) (75)
Base J originally found in kinetoplastida is also a minor constituent of nuclear DNA of Euglena gracilis. (2000) (74)
Telomere exchange can be an important mechanism of variant surface glycoprotein gene switching in Trypanosoma brucei. (1996) (73)
Binding properties of monoclonal antibodies recognizing external epitopes of the human MDR1 P‐glycoprotein (1993) (72)
Biosynthesis and Function of the Modified DNA Base β-d-Glucosyl-Hydroxymethyluracil inTrypanosoma brucei (1998) (72)
Small is beautiful — portrait of a mitochondrial genome (1981) (72)
The modified base J is the target for a nove lDNA‐binding protein in kinetoplastid protozoans (1999) (71)
cGMP transport by vesicles from human and mouse erythrocytes (2007) (71)
The presence of DNA molecules with a displacement loop in standard mitochondrial DNA preparations. (1971) (69)
A variant surface glycoprotein of Trypanosoma brucei synthesized with a C-terminal hydrophobic ‘tail’ absent from purified glycoprotein (1980) (69)
Size-fractionation of the small chromosomes of Trypanozoon and Nannomonas trypanosomes by pulsed field gradient gel electrophoresis. (1986) (67)
Mature mRNAs of Trypanosoma brucei possess a 5' cap acquired by discontinuous RNA synthesis. (1985) (65)
Animal peroxisomes (microbodies), lipid biosynthesis and the Zellweger syndrome (1983) (65)
Trypanosoma brucei: an evaluation of salicylhydroxamic acid as a trypanocidal drug. (1976) (65)
Further characterization of the extremely small mitochondrial ribosomal RNAs from trypanosomes: a detailed comparison of the 9S and 12S RNAs from Crithidia fasciculata and Trypanosoma brucei with rRNAs from other organisms. (1985) (65)
The common 5' terminal sequence on trypanosome mRNAs: a target for anti-messenger oligodeoxynucleotides. (1986) (64)
Further analysis of intraspecific variation in Trypanosoma brucei using restriction site polymorphisms in the maxi-circle of kinetoplast DNA. (1985) (64)
The organization of ribosomal RNA genes in the mitochondrial DNA of Tetrahymena pyriformis strain ST. (1978) (64)
The inactivation and reactivation of an expression‐linked gene copy for a variant surface glycoprotein in Trypanosoma brucei. (1984) (63)
Changing the end: antigenic variation orchestrated at the telomeres of African trypanosomes. (1998) (63)
Do predictive signatures really predict response to cancer chemotherapy? (2010) (62)
Availability of PSC833, a substrate and inhibitor of P-glycoproteins, in various concentrations of serum. (1998) (62)
Telomere conversion in trypanosomes. (1983) (62)
In vivo labelling of intermediates in the discontinuous synthesis of mRNAs in Trypanosoma brucei. (1987) (62)
The structure of kinetoplast DNA. 1. The mini-circles of Crithidia lucilae are heterogeneous in base sequence. (1976) (61)
Transportomics: screening for substrates of ABC transporters in body fluids using vesicular transport assays (2012) (61)
Mechanisms of multidrug-resistance (1994) (61)
The physiological significance of transferrin receptor variations in Trypanosoma brucei. (2002) (60)
The intracellular localization of glutamate-oxaloacetate transaminases in heart. (1961) (59)
The aerobic oxidation of reduced diphosphopyridine nucleotide formed by glycolysis in Ehrlich ascites-tumour cells. (1962) (58)
Trypanosome variant surface glycoprotein genes expressed early in infection. (1985) (58)
The kinetoplast DNA of Trypanosoma equiperdum. (1980) (58)
Selection for activation of a new variant surface glycoprotein gene expression site in Trypanosoma brucei can result in deletion of the old one. (1998) (58)
Mechanisms of MRP over‐expression in four human lung‐cancer cell lines and analysis of the MRP amplicon (1995) (57)
Quantitation of genetic differences between Trypanosoma brucei gambiense, rhodesiense and brucei by restriction enzyme analysis of kinetoplast DNA. (1981) (57)
Targeted metabolomics identifies glucuronides of dietary phytoestrogens as a major class of MRP3 substrates in vivo. (2009) (57)
Hybridization studies with yeast mitochondrial RNAs. (1972) (56)
Tandemly repeated DNA is a target for the partial replacement of thymine by beta-D-glucosyl-hydroxymethyluracil in Trypanosoma brucei. (2000) (56)
Variations in maxi-circle and mini-circle sequences in kinetoplast DNAs from different Trypanosoma brucei strains. (1980) (56)
DNA circles with cruciforms from Isospora (Toxoplasma) gondii. (1984) (55)
Formation of linear inverted repeat amplicons following targeting of an essential gene in Leishmania (2005) (55)
Structure and function of mitochondrial DNA (1977) (55)
Oligomycin sensitivity of the mitochondrial ATPase as a marker for fly transmissability and the presence of functional kinetoplast DNA in African trypanosomes. (1976) (55)
J‐binding protein increases the level and retention of the unusual base J in trypanosome DNA (2002) (55)
The site of action of 2,4-dinitrophenol on oxidative phosphorylation (1961) (54)
Antigenic variation in Trypanosoma brucei: a telomeric expression site for variant-specific surface glycoprotein genes with novel features. (1991) (54)
Circular DNA of 3T6R50 double minute chromosomes. (1988) (54)
The potential impact of drug transporters on nucleoside-analog-based antiviral chemotherapy. (2004) (54)
Evidence for gene conversion between the phosphoglycerate kinase genes of Trypanosoma brucei. (1988) (54)
Mitochondrial DNA. II. Sedimentation analysis and electron microscopy of mitochondrial DNA from chick liver. (1967) (53)
The oxidation of glutamate by rat-heart sarcosomes. (1960) (53)
Renaturation of mitochondrial DNA. (1966) (53)
The effect of temperature and ionic strength of the electrophoretic mobility of yeast mitochondrial RNA. (1971) (53)
Transcription of kinetoplast DNA in Trypanosoma brucei bloodstream and culture forms. (1981) (52)
Size fractionation of Trypanosoma brucei DNA: localization of the 177-bp repeat satellite DNA and a variant surface glycoprotein gene in a mini-chromosomal DNA fraction. (1983) (52)
Why kinetoplast DNA networks? (1991) (51)
Pulsed field gradient electrophoresis of DNA digested in agarose allows the sizing of the large duplication unit of a surface antigen gene in trypanosomes. (1986) (51)
The structure of kinetoplast DNA. 2. Characterization of a novel component of high complexity present in the kinetoplast DNA network of Crithidia luciliae. (1976) (50)
One gene's intron is another gene's exon (1981) (50)
Factors Affecting the Level and Localization of the Transferrin Receptor in Trypanosoma brucei* (2004) (50)
Conditions that prevent ϱ−-induction by ethidium bromide (1971) (50)
Rapid evolution of genes coding for variant surface glycoproteins in trypanosomes. (1982) (50)
MRP 3 , an organic anion transporter able to transport anti-cancer drugs ( multidrug resistance y methotrexate y etoposide ) (1999) (49)
Cancer cell death by programmed necrosis? (2004) (49)
Characteristics of trypanosome variant antigen genes active in the tsetse fly (1985) (49)
Trypanosomes change their transferrin receptor expression to allow effective uptake of host transferrin (2005) (48)
DNA‐DNA Hybridization on Nitrocellulose Filters (1974) (48)
N-lactoyl-amino acids are ubiquitous metabolites that originate from CNDP2-mediated reverse proteolysis of lactate and amino acids (2015) (48)
The maxi-circle of Trypanosoma brucei kinetoplast DNA. (1979) (48)
Secondary loss of chloroplasts in trypanosomes (2003) (48)
Splice point sequence and transcripts of the intervening sequence in the mitochondrial 21S ribosomal RNA gene of yeast (1980) (48)
Targeting of exogenous DNA into Trypanosoma brucei requires a high degree of homology between donor and target DNA. (1996) (47)
Impact of intertumoral heterogeneity on predicting chemotherapy response of BRCA1-deficient mammary tumors. (2012) (47)
A ribosomal RNA gene promoter at the telomere of a mini-chromosome in Trypanosoma brucei. (1992) (46)
Antigenic variation in trypanosomes. (1996) (46)
Control of antigenic variation in African trypanosomes. (1993) (46)
Genetic transfer of non-P-glycoprotein-mediated multidrug resistance (MDR) in somatic cell fusion: dissection of a compound MDR phenotype. (1992) (46)
REPLICATION OF VIRAL RNA. (1964) (46)
Mitochondrial nucleic acids. (1974) (45)
Frequent Loss of the Active Site during Variant Surface Glycoprotein Expression Site Switching In Vitro inTrypanosoma brucei (1998) (44)
The organization of gene in yeast mitochondrial DNA (2004) (44)
Transferrin receptor, antigenic variation and the prospect of a trypanosome vaccine. (1991) (44)
REPLICATION OF VIRAL RNA. IV. PROPERTIES OF RNA SYNTHETASE AND ENZYMATIC SYNTHESIS OF MS2 PHAGE RNA. (1964) (44)
DNA rearrangements involving the genes for variant antigens in Trypanosoma brucei. (1981) (44)
Does resistance to apoptosis affect clinical response to antitumor drugs? (2001) (44)
Mechanisms of antigenic variation in African trypanosomes. (1997) (43)
RNA from the insect trypanosome Crithidia luciliae contains transcripts of the maxi-circle and not of the mini-circle component of kinetoplast DNA. (1978) (43)
beta-D-glucosyl-hydroxymethyluracil, a novel base in African trypanosomes and other Kinetoplastida. (1997) (43)
Specific detection of kinetoplast DNA in cytological preparations of trypanosomes by hybridization with complementary RNA. (1973) (43)
BRCA2-deficient sarcomatoid mammary tumors exhibit multidrug resistance. (2015) (43)
DNA synthesis by isolated mitochondria. I. Effect of inhibitors and characterization of the product. (1971) (42)
The glutamate dehydrogenases of yeast: extra-mitochondrial enzymes. (1970) (42)
ATP-binding Cassette Subfamily C Member 5 (ABCC5) Functions as an Efflux Transporter of Glutamate Conjugates and Analogs* (2015) (42)
ACCUMULATION OF REPLICATIVE INTERMEDIATES OF MITOCHONDRIAL DNA IN TETRAHYMENA PYRIFORMIS GROWN IN ETHIDIUM BROMIDE (1974) (42)
The expression level determines the surface distribution of the transferrin receptor in Trypanosoma brucei (2002) (42)
Trypanosoma brucei: a surface antigen mRNA is discontinuously transcribed from two distinct chromosomes. (1985) (42)
Stable transformation of Trypanosoma brucei. (1993) (41)
Size, structure and genetic complexity of yeast mitochondrial DNA. (1969) (41)
Sequence heterogeneity of the mini-circles of kinetoplast DNA of Crithidia luciliae and evidence for the presence of a component more complex than mini-circle DNA in the kinetoplast network. (1975) (41)
RNA end-labeling and RNA ligase activities can produce a circular rRNA in whole cell extracts from trypanosomes. (1987) (41)
The unusual properties of mtDNA from a "low-density" petite mutant of yeast. (1972) (41)
Maxi-circles and mini-circles in kinetoplast DNA from trypanosoma cruzi. (1980) (40)
The number of 4-S RNA genes on yeast mitochondrial DNA. (1972) (40)
Structure and transcription of a telomeric surface antigen gene of Trypanosoma brucei (1985) (40)
Mitochondrial DNA. 3. Electron microscopy of DNA released from mitochondria by osmotic shock. (1968) (39)
Chromosomal localization of three genes coamplified in the multidrug-resistant CHRC5 Chinese hamster ovary cell line. (1987) (39)
The control of variant surface antigen synthesis in trypanosomes. (1983) (39)
Telomeric localization of the modified DNA base J in the genome of the protozoan parasite Leishmania (2007) (39)
The viral thymidine kinase gene as a tool for the study of mutagenesis in Trypanosoma brucei. (1996) (39)
Characterization of the expression-linked gene copies of variant surface glycoprotein 118 in two independently isolated clones of Trypanosoma brucei. (1982) (38)
Identification of the heavy strand of rat-liver mitochondrial DNA as the messenger strand. (1969) (38)
Variation with temperature of the apparent molecular weight of rat-liver mitochondrial RNA, determined by gel electrophoresis. (1970) (38)
Kinetoplast DNA (1993) (38)
The structure of Tetrahymena pyriformis mitochondrial DNA. I. Strain differences and occurrence of inverted repetitions. (1977) (38)
Multidrug resistance-associated protein 9 (ABCC12) is present in mouse and boar sperm. (2007) (37)
Drug resistance in the mouse cancer clinic. (2012) (37)
Kinetoplast DNA from Trypanosoma vivax and T. congolense. (1985) (36)
Mapping of VSG genes on large expression-site chromosomes of Trypanosoma brucei separated by pulsed-field gradient electrophoresis. (1986) (36)
Replication of viral RNA, 8. Studies on the enzymatic mechanism of replication of MS2 RNA. (1965) (36)
Reduced topoisomerase II activity in multidrug-resistant human non-small cell lung cancer cell lines. (1995) (35)
Human multidrug resistance 3-P-glycoprotein expression in transgenic mice induces lens membrane alterations leading to cataract (1996) (35)
Two simultaneously active VSG gene transcription units in a single trypanosoma brucei variant (1985) (35)
Coincident multiple activations of the same surface antigen gene in Trypanosoma brucei. (1987) (35)
Recognition of Base J in Duplex DNA by J-binding Protein* (2002) (34)
The tissue dependent expression of hamster P‐glycoprotein genes (1988) (34)
The structure of kinetoplast DNA. I. Properties of the intact multi-circular complex from Crithidia luciliae. (1975) (34)
The synthesis and utilization of dCDP-diglyceride by a mitochondrial fraction from rat liver. (1971) (34)
Ethidium DNA agarose gel electrophoresis: How it started (2005) (33)
Preparation and Properties of Mitochondria from Ehrlich Ascites Tumor Cells (1960) (32)
Tumor-initiating cells are not enriched in cisplatin-surviving BRCA1;p53-deficient mammary tumor cells in vivo (2010) (32)
Mitochondrial DNA from cytoplasmic petite mutants of yeast. (1972) (32)
Boundaries of telomere conversion in Trypanosoma brucei. (1988) (32)
Introduction: multidrug resistant proteins (1997) (31)
Stable introduction of exogenous DNA into Trypanosoma brucei. (1987) (31)
Evidence that J-binding protein 2 is a thymidine hydroxylase catalyzing the first step in the biosynthesis of DNA base J. (2009) (30)
Availability of PSC833, a Substrate and Inhibitor of P-glycoproteins, in Various Concentrations of Serum (1998) (30)
The Physical Map of Yeast Mitochondrial DNA Anno 1977 (A Review) (1977) (30)
Trypanosoma brucei variant-specific glycoprotein gene chromatin is sensitive to single-strand-specific endonuclease digestion. (1987) (30)
The molecular weights of the mitochondrial-ribosomal RNAs of Saccharomyces carlsbergensis. (1973) (30)
DNA synthesis by isolated mitochondria. II. Detection of product DNA hydrogen-bonded to closed duplex circles. (1971) (30)
Kinetoplast DNA in the insect trypanosomes Crithidia luciliae and Crithidia fasciculata. I. Sequence evolution and transcription of the maxicircle. (1982) (30)
Inhibition of the multidrug resistance protein 1 (MRP1) by peptidomimetic glutathione-conjugate analogs. (2002) (30)
Replication of the linear mitochondrial DNA of Tetrahymena pyriformis. (1979) (30)
PXE, a Mysterious Inborn Error Clarified. (2019) (29)
Mitochondrial DNA. IV. Interaction of ribopolynucleotides with the complementary strands of chick-liver mitochondrial DNA. (1969) (29)
DNA synthesis by isolated mitochondria. 3. Characterization of D-loop DNA, a novel intermediate in mtDNA synthesis. (1971) (29)
Erroneous transcription of mitochondrial DNA by RNA polymerase from Escherichia coli. (1970) (28)
The structural basis for recognition of base J containing DNA by a novel DNA binding domain in JBP1 (2011) (27)
Expression site activation in Trypanosoma brucei with three marked variant surface glycoprotein gene expression sites. (2002) (27)
The organization of genes in yeast mitochondrial DNA (2004) (27)
The number of superhelical turns in mitochondrial DNA. (1968) (27)
THE REPLICATIVE FORM OF MS2 RNA: AN X-RAY DIFFRACTION STUDY. (1964) (26)
Investigation of the alpha-galactosidase deficiency in Fabry's disease using antibodies against the purified enzyme. (1974) (26)
Properties of mitochondrial DNA from Kluyveromyces lactis. (1974) (26)
Transcription of a transposed trypanosome surface antigen gene starts upstream of the transposed segment. (1985) (26)
cDNA cloning and tissue-specific expression of the phosphatidylcholine transfer protein gene. (1996) (25)
ABCC6 does not transport vitamin K3-glutathione conjugate from the liver: relevance to pathomechanisms of pseudoxanthoma elasticum. (2011) (25)
Defining the sequence requirements for the positioning of base J in DNA using SMRT sequencing (2015) (25)
Deficiency of plasmalogens in the cerebro-hepato-renal (Zellweger) syndrome (1984) (25)
The expression sites for variant surface glycoproteins of Trypanosoma brucei. (1997) (25)
An analysis by electron microscopy of intermediates in the replication of linear Tetrahymena mitochondrial DNA. (1974) (25)
EZN-2208 (PEG-SN38) Overcomes ABCG2-Mediated Topotecan Resistance in BRCA1-Deficient Mouse Mammary Tumors (2012) (25)
Characterization of kinetoplast DNA networks from the insect trypanosome Crithidia luciliae. (1977) (25)
Structure of a telomeric expression site for variant specific surface antigens in Trypanosoma brucei. (1990) (24)
Rapid change of the repertoire of variant surface glycoprotein genes in trypanosomes by gene duplication and deletion. (1986) (24)
On the putative co‐transport of drugs by multidrug resistance proteins (2006) (24)
Kinetoplast DNA in the insect trypanosomes Crithidia luciliae and Crithidia fasciculata. II. Sequence evolution of the minicircles. (1982) (24)
Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality. (2019) (24)
STRUCTURE AND FUNCTION OF KINETOPLAST DNA OF THE AFRICAN TRYPANOSOMES (1979) (24)
The organization of genes in yeast mitochondrial DNA (1975) (23)
Characterization of the promoter region of the human MDR3 P-glycoprotein gene. (1995) (23)
Altered MRP is associated with multidrug resistance and reduced drug accumulation in human SW-1573 cells. (1995) (23)
The modified DNA base beta-D-glucosyl-hydroxymethyluracil is not found in the tsetse fly stages of Trypanosoma brucei. (1998) (23)
A phosphoglycerate kinase-related gene conserved between Trypanosoma brucei and Crithidia fasciculata. (1992) (22)
vidence that J-binding protein 2 is a thymidine hydroxylase catalyzing he first step in the biosynthesis of DNA base (2009) (22)
Delineation of the regulated Variant Surface Glycoprotein gene expression site domain of Trypanosoma brucei. (2003) (22)
Mechanisms of Antigenic Variation: An Overview (2003) (22)
Expression of the human DNA glycosylase hSMUG1 in Trypanosoma brucei causes DNA damage and interferes with J biosynthesis. (2002) (22)
The modified DNA base beta-D-glucosylhydroxymethyluracil confers resistance to micrococcal nuclease and is incompletely recovered by 32P-postlabeling. (1998) (22)
Transcription of mitochondrial DNA. (1983) (21)
Multidrug resistant proteins. (1997) (21)
Mitochondrial RNA from rat liver. (1970) (21)
Analysis by electron microscopy of the variable segment in the maxi-circle of kinetoplast DNA from Trypanosoma brucei. (1982) (21)
Controlled turnover and 3' trimming of the trans splicing precursor of Trypanosoma brucei. (1987) (21)
Hybridization studies with RNA synthesized by isolated rat-liver mitochondria. (1970) (21)
Multidrug resistance: a solvable problem? (1999) (21)
Reactions involved in energy transfer in trypanosomes-I. Characterization of the mitochondrial adenine nucleotide translocator and the ATPase of Crithidia luciliae. (1976) (20)
ADP-ribosyl transferase activity in Trypanosoma brucei. (1985) (20)
Induction of RNA Synthetase in E. coli after Infection by the RNA Phage, MS2 (1963) (20)
Site-specific Interactions of JBP with Base and Sugar Moieties in Duplex J-DNA (2002) (20)
Selected Alkylating Agents Can Overcome Drug Tolerance of G0-like Tumor Cells and Eradicate BRCA1-Deficient Mammary Tumors in Mice (2017) (20)
Conservation of the sequence and position of the ribosomal RNA genes in Tetrahymena pyriformis mitochondrial DNA. (1978) (19)
The structure of ribosome-like particles from rat-liver mitochondria. (1972) (19)
Detection and properties of an acid -galactosidase (ceramidetrihexosidase) in normal human urine. (1972) (18)
A study of minor RNA components of rat-liver microsomes. (1971) (18)
Mitochondrial ribosomes (1971) (18)
Maxi-circles in the kinetoplast DNA of Trypanosoma mega. (1977) (18)
Effect of 3-aminobenzamide on antigenic variation of Trypanosoma brucei. (1985) (18)
Are 50% of all cellular proteins synthesized on mitochondrial ribosomes in Crithidia luciliae? (1975) (17)
Changes in expression site control and DNA modification in Trypanosoma brucei during differentiation of the bloodstream form to the procyclic form. (1998) (17)
Cancer chemotherapy: DNA amplification and multidrug resistance (1984) (17)
The kinetoplast DNA of Trypanosoma brucei: structure, evolution, transcription, mutants. (1980) (17)
Structure, function and evolution of kinetoplast DNA. (1981) (16)
Peripheral Neuropathy in Mice Transgenic for a HumanMDR3 P-Glycoprotein Mini-Gene (1996) (16)
Looking back at multidrug resistance (MDR) research and ten mistakes to be avoided when writing about ABC transporters in MDR (2020) (16)
The genes for variant antigens in trypanosomes. (1980) (16)
Mitochondrial mosaics — maturases on the move (1982) (16)
Transcription of Tetrahymena mitochondrial DNA in vivo. (1973) (16)
Structure of amplified DNA, analyzed by pulsed field gradient gel electrophoresis (1987) (15)
Intramitochondrial localization of 5-aminolaevulinate synthase induced in rat liver with allylisopropylacetamide. (1969) (15)
Pyrimidine tract analysis of mtDNA from a "low-density" petite mutant of yeast. (1972) (15)
Nucleoside analysis of DNA from Trypanosoma brucei and Trypanosoma equiperdum. (1988) (15)
Need for Inorganic Phosphate in Oxidations stimulated by Dinitrophenol (1959) (15)
THE DPN CONTENT OF MITOCHONDRIA ISOLATED FROM ASCITES- TUMOUR CELLS TREATED WITH A CARCINOSTATIC ETHYLENEIMINE. (1963) (15)
A minor fraction of base J in kinetoplastid nuclear DNA is bound by the J-binding protein 1. (2005) (15)
DNA-DNA hybridization on nitrocellulose filters. 2. Concatenation effects. (1974) (15)
Platelet-activating factor: mediator of the third pathway of platelet aggregation? A study in three patients with deficient platelet-activating factor synthesis. (1987) (14)
Metabolism and chemotherapy of African trypanosomes. (1977) (14)
THE USE OF RECOMBINANT DNA TECHNIQUES IN THE ANALYSIS OF TRYPANOSOMA BRUCEI KINETOPLAST DNA (1980) (14)
Fine structure physical mapping of 4S RNA genes on mitochondrial DNA ofSaccharomyces cerevisiae (1977) (13)
Binding of the J-binding protein to DNA containing glucosylated hmU (base J) or 5-hmC: evidence for a rapid conformational change upon DNA binding. (2012) (13)
Parasitology: Switching like for like (2006) (13)
Transporters as Drug Carriers: Structure, Function, Substrates (2010) (13)
[Multiple D-loops in Tetrahymena mitochondrial DNA]. (1972) (13)
Base J, found in nuclear DNA of Trypanosoma brucei, is not a target for DNA glycosylases. (2004) (12)
CHAPTER 21 – THE MULTIDRUG RESISTANCE PROTEINS 3–7 (2003) (12)
Insertion of the promoter for a variant surface glycoprotein gene expression site in an RNA polymerase II transcription unit of procyclic Trypanosoma brucei. (1993) (12)
The pyridine nucleotide content of mitochondria isolated from Ehrlich ascites tumour cells. (1962) (12)
Mega-dose vitamin C as therapy for human cancer? (2008) (11)
Expression of HumanMRP6, a Homologue of the Multidrug Resistance Protein GeneMRP1, in Tissues and Cancer Cells (1998) (11)
An analysis of a possible base sequence complementarity of mitochondrial and nuclear DNA in yeast. (1970) (11)
The structure of Tetrahymena pyriformis mitochondrial DNA. II. The complex structure of strain GL mitochondrial DNA. (1977) (11)
New physiological functions for drug-transporting P-glycoproteins? (1998) (11)
DNA synthesis by isolated mitochondria. IV. Isolation of an intermediate containing newly synthesized DNA in full-length light strands. (1972) (11)
Fine structure of the 21S ribosomal RNA region on yeast mitochondrial DNA (1979) (11)
DNA-DNA hybridization on nitrocellulose filters. 1. General considerations and non-ideal kinetics. (1974) (11)
Advances in Brief Antifolate Resistance Mediated by the Multidrug Resistance Proteins MRP 1 and MRP 21 (2000) (10)
Reinvestigation into the Synthesis of Oligonucleotides Containing 5‐(β‐D‐Glucopyranosyloxymethyl)‐2′‐deoxyuridine (2003) (10)
Amplification of Several Different Genes in Multidrug-Resistant Chinese Hamster Cell Lines (1991) (10)
GENE EXPRESSION AND ORGANIZATION IN TRYPANOSOME MITOCHONDRIA (1983) (10)
Mitochondrial DNA: structure, information content, replication and transcription. (1970) (9)
Multidrug resistance in human lung cancer (1993) (9)
Search for mitochondrial DNA sequences in chick nuclear DNA. (1973) (9)
Conditions that prevent rho - -induction by ethidium bromide. (1971) (9)
Lack of ABCG2 Shortens Latency of BRCA1-Deficient Mammary Tumors and This Is Not Affected by Genistein or Resveratrol (2012) (9)
Intermediates in the replication of the mitochondrial DNA of Tetrahymena pyriformis. (1974) (8)
Intestinal BCRP/Bcrp1 and MRP3/Mrp3 are involved in the pharmacokinetics of resveratrol (2008) (8)
The binding of polyribonucleotides to the complementary strands of mitochondrial DNA. (1972) (8)
Analysis of a variant surface glycoprotein gene expression site promoter of Trypanosoma brucei by remodelling the promoter region. (1998) (8)
Mono-allelic expression of genes in simple eukaryotes. (1999) (8)
Introduction to the Blood–Brain Barrier: P-glycoprotein, a guardian of the brain (1998) (8)
The genes for the variable surface glycoproteins of Trypanosoma brucei. (1980) (8)
Formation of self-complementary RNA on a single strand of DNA by RNA polymerase from Escherichia coli. (1971) (8)
The Optional Introns in Yeast Mitochondrial DNA (1980) (7)
Molecular genetics of antigenic variation (1991) (7)
A fused chimeric protein made in human cells (1989) (7)
Replicative Intermediates of Tetrahymena pyriformis Mitochondrial Deoxyribonucleic Acid (1974) (6)
The Evolutionary Origin of Glycosomes: How Glycolysis Moved from Cytosol to Organelle in Evolution (1989) (6)
DNA synthesis by isolated mitochondria. V. Electron microscopy of replicative intermediates. (1973) (6)
Faculty Opinions recommendation of MED12 controls the response to multiple cancer drugs through regulation of TGF-β receptor signaling. (2013) (6)
Differentiation of haemoflagellate species by hybridization of complementary RNA with kinetoplast DNA. (1973) (6)
The Biogenesis of Mitochondria - a Review (1976) (6)
Kinetoplast DNA in the insect trypanosomes Crithidia luciliae and Crithidia fasciculata. III. Heteroduplex analysis of the C. luciliae minicircles. (1982) (6)
Analysis of telomere length variation in Leishmania over time. (2007) (6)
Mitochondrial DNA. V. A 25 micron closed circular duplex DNA molecule in wild-type yeast mitochondria. Stucture and genetic complexity. (1970) (6)
Fine structure of the 21S ribosomal RNA region on yeast mitochondrial DNA (1979) (6)
Antigenic Variation in Eukaryotic Parasites (2002) (5)
Translation of Mitochondrial Messenger RNA's in vitro as an Approach to the Identification of Gene Products of Yeast Mitochondrial DNA (1976) (5)
Biochemical methods to locate genes on the physical map of yeast mitochondrial DNA. (1979) (5)
Molecular parasitology at woods hole (1992) (5)
DNA amplification and multidrug resistance. (1984) (5)
Response of BRCA 1-Deficient Mammary Tumors Impact of Intertumoral Heterogeneity on Predicting Chemotherapy (2012) (5)
Mosaic genes and RNA processing in mitochondria. (1983) (5)
REV 7 counteracts DNA double-strand break resection and impacts PARP inhibition (2015) (5)
STRUCTURE OF PETITE mtDNA; PROSPECTS FOR MITOCHONDRIAL GENE ISOLATION, MAPPING AND SEQUENCING (1974) (4)
Optimal conditions for primer-dependent transcription of poly (dT) by RNA polymerase. (1973) (4)
Preface/Front Matter (1982) (4)
Biosynthesis, and Possible Functions (2008) (4)
Antifolates Folates and Can Mediate Cellular Resistance against The Human Multidrug Resistance Protein MRP 5 Transports (2005) (4)
How mycoplasma ring the changes (1992) (4)
Studying cancer drug resistance using BRCA-deficient mouse mammary tumor organoids (2017) (3)
Basolateral hepatic export of bile acid glucuronides via MRP3: An important route for bile acid detoxification? (2003) (3)
Multidrug resistance. (1989) (3)
Translation Products in Isolated Mitochondria from Neurospora crassa: Partial Assembly of Cytochrome Oxidase Components (1976) (3)
The Biogenesis of Mitochondria in Yeast and Other Primitive Eukaryotes (1981) (3)
Genes on Saccharomyces Mitochondrial DNA (1976) (3)
Ananalysis ofcosmid clones ofnuclear DNA fromTrypanosoma brucei showsthat thegenes for variant surface glycoproteins areclustered inthegenome (1982) (3)
CHAPTER 22 – LIPID TRANSPORT BY ABC TRANSPORTERS (2003) (3)
The organization of repeating units in mitochondrial DNA from yeast petite mutants (1980) (3)
Maxi-circles, glycosomes, gene transposition, expression sites, transsplicing, transferrin receptors and base J. (2016) (3)
Gene rearrangements controlling gene expression. (1986) (3)
Mrp4 expression in wildtype and Mrp4 -/- mice (2004) (3)
Unicellular eukaryotes are not devoid of ADPRT (1987) (2)
Bill Slater at 90 (2007) (2)
Cancer Resistance Protein in Clinical Drug-Drug Interactions Methotrexate and Benzimidazoles : Potential Role for Breast Mechanism of the Pharmacokinetic Interaction between Updated (2004) (2)
Comparative Immunological and Electrophoretic Studies of the Cytochrome bc1 Complex of Different Organisms (1976) (2)
Transport of glutathione A conjugates by the multifrug resistance protein 1 (1997) (2)
Pumping Out Drugs The Potential Impact of ABC Transporters on Resistance to Base, Nucleoside, and Nucleotide Analogs* (2007) (2)
The Use of Isolated Mitochondria in the Study of Mitochondrial Biogenesis (1976) (2)
From cancer cells to trypanosomes and back again (2006) (2)
How I became a biochemist (2006) (2)
Structure and Function of P-Glycoproteins (1992) (1)
CLONING AND ANALYSIS OF GENES FOR SOME GLYCOSOMAL ENZYMES OF TRYPANOSOMA-BRUCEI (1986) (1)
The Synthesis of Yeast Mitochondrial Proteins in Cell-free Systems (1976) (1)
Disaggregation of Mitochondrial Translation Products to Small Polypeptides by Performic Acid Oxidation (1976) (1)
THE ROLE OF BILIARY CHOLESTEROL AND PHOSPHOLIPIDS IN THE REGULATION OF PLASMA-LIPID LEVELS - STUDIES IN MDR2 TRANSGENIC MICE (1994) (1)
Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier Wijnholds, (2000) (1)
Pumping Out Drugs (2006) (1)
The physiological role of mdr2 P-glycoprotein in hepatobiliary phospholipid transport (1997) (1)
Faculty Opinions recommendation of Zosuquidar, a novel modulator of P-glycoprotein, does not improve the outcome of older patients with newly diagnosed acute myeloid leukemia: a randomized, placebo-controlled trial of the Eastern Cooperative Oncology Group 3999. (2011) (1)
The pyridine nucleotide content of mitochondria of ehrlich ascites tumour cells. (1960) (1)
Abstract 3198: MRP4 Acts in Balance With Phosphodiesterases to Regulate cAmp-dependent Signalling Pathway in Cardiac Myocytes (2009) (1)
Lack of ABCG 2 shortens latency of BRCA 1-deficient mammary tumors and this is not 1 affected by genistein or resveratrol 2 3 (2012) (1)
Need for Inorganic Phosphate in Oxidations stimulated by Dinitrophenol (1959) (1)
Physiological functions of proteins involved in MDR: 153 (1994) (1)
Edward Charles Slater. 16 January 1917 — 26 March 2016 (2017) (1)
Domain VII of other eukaryotic 28S rRNAs (1)
Abstract 736: Combining PD1- and CTLA4-inhibiting antibodies with cisplatin or PARP inhibition in an attempt to eradicate BRCA1-deficient mouse mammary tumors (2015) (1)
DNA REARRANGEMENTS ASSOCIATED WITH ANTIGENIC VARIATION IN TRYPANOSOMES (1981) (0)
Substantial excretion ofdigoxin viatheintestinal mucosa and prevention oflong-term digoxin accumulation inthebrain bythe mdrlaP-glycoprotein (1996) (0)
DNAA modification and base excision repair in Trypanosoma brucei (2007) (0)
Alternative mechanisms of multidrug resistance cancer (1996) (0)
Abstract 3607: Loss-of-function screens using haploid KBM7 and HAP1 cells to identify mechanisms of anti-cancer drug resistance (2015) (0)
Abstract 3771: Splenic macrophages induce chemotherapy resistance via DNA damage repair (2014) (0)
Abstract PL6-1: Resistance to targeted therapies in a realistic mouse breast cancer model (2010) (0)
Molecular Basis for Trypanosome Antigenic Variation Review (1982) (0)
Species named (reply) (1984) (0)
Reinvestigation into the Synthesis of Oligonucleotides Containing 5-(β-D-Glucopyranosyloxymethyl)-2′-deoxyuridine. (2004) (0)
III. Korrelationen zwischen Zellkompartimenten Hydrogen transport and transport metabolites (1963) (0)
Induced Pneumonia pneumoniae-Streptococcus Protein 1 Are Resistant to Mice Lacking the Multidrug Resistance (2001) (0)
The identification of the active component of mitochrome, and the influence of long-chain fatty acids on the adenosine triphosphatase activity of rat-liver mitochondria† (2010) (0)
Mini-review MRP 2 and 3 in health and disease (2006) (0)
Circular DNA molecules with cruciforms examined in the electron microscope. A tool for studying DNA structure in vivo (1986) (0)
Compared Properties of the Oligomycin-sensitive ATPase in Fungi with short and long Mitochondrial DNA (1976) (0)
[2. Introduction] (2018) (0)
381 INVITED Preclinical Evaluation of PARP Inhibitors in Mouse Models of Human Breast Cancer (2011) (0)
Studies On the Genes for Glycolytic-enzymes of Trypanosoma-brucei (1985) (0)
Stable introduction of exogenoud DNA into Trypsnosoma brucei (1987) (0)
Phosphatidylcholline transfer protein (PC-TP) (2002) (0)
CHAPTER 4 XRN 2 loss causes PARP inhibitor and cisplatin resistance of BRCA 1-deficient mouse mammary tumor cells (2015) (0)
Abstract 5584: Finding predictive markers for tumor response to classical cytotoxic drugs. (2013) (0)
Basoloteral hepatic export of bile acid glucuronides via MRP3: An important route for bile acid detoxification? (2003) (0)
THE REPLICA TIVE FORM OF MS2 RNA: AN X-RAY DIFFRACTION STUDY* (0)
Expressionn site activation in Trypanosoma brucei with threee marked variant surface glycoprotein gene expressionn sites (2007) (0)
Antigenic variation in infectious diseases: edited by T. H. Birkbeck and C. W. Penn, IRL Press, 1986. £32.00/$58.00 (hbk) /sP20.00/$36.00 (pbk) (x + 170 pages) ISBN 0 94746 99 3 (1987) (0)
Altered pharmacokinetics of vinblastine in mice with a homozygous disruption of the MDR1a P-glycoprotein gene: 2 (1994) (0)
The contribution of ABC transporters to drug resistance in a realistic mouse mammary tumor model (2010) (0)
Nucleic Acids Research (2013) (0)
atAmanitinwinsensitive transcrption of variant surface glycoprotein genes provides further evidence for discontinuous tiption in trypanosomes (0)
Analysis of the chromosomal location of the VSG genes and their expression sites in two trypanosome clone derivations (1986) (0)
Further characterization oftheextremely small mitochondrial ribosomal RNAsfrom trypanosomes: adetailed comparison ofthe9Sand12SRNAsfromCrithidia fasciculata and Trypanosoma brucei withrRNAsfromother organisms (1985) (0)
DNA content and structure of (double) minutes of a methotrexate-resistant cell line (2004) (0)
Resistant Lung Cancer Cell Lines Transmembrane Drug Transporter , in Human Multidrug , the Gene for a New Putative MRP Analysis of the Expression of Updated Version (2006) (0)
Identification and Analysis of the Glycolytic Genes of Trypanosoma-brucei (1986) (0)
Control of surface antigen genes in African trypanosomes. (1990) (0)
DNA ASSOCIATED WITH TOBACCO CHLOROPLASTS (1965) (0)
Abstract A14: Lack of tumor eradication of chemotherapy-sensitive BRCA1;p53-deficient mouse mammary tumors (2010) (0)
Resistance to natural products in leukemia. (1990) (0)
Control of variant-specific surface glycoprotein expression sites in Trypanosoma-brucei (1989) (0)
Subunit Structure and Biogenesis of Cytochrome b from Neurospora crassa (1976) (0)
Table of Contents (1984) (0)
Modification of tdomeric DNA in Trypanosoma brucei; a role in antigenk variation? (1984) (0)
Multienzyme systems — some objections to -some (1980) (0)
HELB Is a Feedback Inhibi tor of DNA End Resection Graphical Abstract Highlights (2016) (0)
Recognition by P-Glycoprotein-specific Monoclonal Antibodies 3 P-Glycoprotein and Its MDR Characterization of the Human Updated Version (2006) (0)
Search for mitochondrial DNA sequences in chick nuclear DNA. (1973) (0)
Faculty Opinions recommendation of A haploid genetic screen identifies the major facilitator domain containing 2A (MFSD2A) transporter as a key mediator in the response to tunicamycin. (2011) (0)
Abstracts of papers presented at the Meeting on Mitochondrial Genes, May 13-May 17, 1981 (1981) (0)
Targeting G0-like Residual Cells in a Mouse Model for BRCA1-deficient Mammary Tumours (2017) (0)
The preparation and properties of mitochondria from Ehrlich ascites cells. (1961) (0)
Biosynthesis and function of base J, a new base in the nuclear DNA of kinetoplastid parasites (1993) (0)
Mechanisms of chemotherapy resistance in spontaneous tumors of genetically modified mice (2006) (0)
Faculty Opinions recommendation of ZNF423 is critically required for retinoic acid-induced differentiation and is a marker of neuroblastoma outcome. (2009) (0)
A study of drug resistance mechanisms using large-scale RNA interference screens (2005) (0)
Abstract LB-392: Loss of Rev7 causes PARP inhibitor resistance in BRCA1;p53-deficient mouse mammary tumor cells (2012) (0)
The construction of the physical maps of three different Saccharomyces mitochondrial DNAs (2004) (0)
Table of Contents (1990) (0)
Doxorubicin sensitivity and acquired resistance of Pgp-and BRCA 1-deficient mouse mammary tumors (2012) (0)
The oxidation of glutamate by rat-heart sarcosomes. 1960. (1989) (0)
Renaturation of denatured DNA in NaI gradients (1974) (0)

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What Schools Are Affiliated With Piet Borst?

Piet Borst is affiliated with the following schools: