Poonam Salotra
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Indian medical researcher
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Poonam Salotra's Degrees
- PhD Medical Research Postgraduate Institute of Medical Education and Research
Why Is Poonam Salotra Influential?
(Suggest an Edit or Addition)According to Wikipedia, Poonam Salotra is an Indian scientist and researcher, appointed as Consultant at the ICMR-National Institute of Pathology whose work is centered on infectious diseases like Visceral Leishmaniasis , Anthrax, Tuberculosis and Cholera. Her research covers the development of diagnostic tests and attenuated vaccines, drug resistance and immune responses for patients with Leishmaniasis in some form.
Poonam Salotra's Published Works
Published Works
- Development of a Species-Specific PCR Assay for Detection of Leishmania donovani in Clinical Samples from Patients with Kala-Azar and Post-Kala-Azar Dermal Leishmaniasis (2001) (202)
- Quantification of Parasite Load in Clinical Samples of Leishmaniasis Patients: IL-10 Level Correlates with Parasite Load in Visceral Leishmaniasis (2010) (141)
- Diagnosis of visceral leishmaniasis: developments over the last decade (2012) (125)
- Elevated levels of interferon-gamma, interleukin-10, and interleukin-6 during active disease in Indian kala azar. (2006) (124)
- Cutaneous leishmaniasis caused by Leishmania tropica in Bikaner, India: parasite identification and characterization using molecular and immunologic tools. (2007) (120)
- Challenges in the diagnosis of post kala-azar dermal leishmaniasis. (2006) (119)
- Centrin Gene Disruption Impairs Stage-specific Basal Body Duplication and Cell Cycle Progression in Leishmania* (2004) (115)
- Drug Susceptibility in Leishmania Isolates Following Miltefosine Treatment in Cases of Visceral Leishmaniasis and Post Kala-Azar Dermal Leishmaniasis (2012) (100)
- Live Attenuated Leishmania donovani p27 Gene Knockout Parasites Are Nonpathogenic and Elicit Long-Term Protective Immunity in BALB/c Mice (2013) (91)
- In Vitro Susceptibility of Field Isolates of Leishmania donovani to Miltefosine and Amphotericin B: Correlation with Sodium Antimony Gluconate Susceptibility and Implications for Treatment in Areas of Endemicity (2008) (90)
- Multilocus microsatellite typing (MLMT) reveals genetic homogeneity of Leishmania donovani strains in the Indian subcontinent. (2009) (89)
- Evaluation of PCR for Diagnosis of Indian Kala-Azar and Assessment of Cure (2005) (89)
- Characterization of a Leishmania stage‐specific mitochondrial membrane protein that enhances the activity of cytochrome c oxidase and its role in virulence (2010) (80)
- Expression of a Mutant Form of Leishmania donovani Centrin Reduces the Growth of the Parasite* (2001) (78)
- Immunity to Visceral Leishmaniasis Using Genetically Defined Live-Attenuated Parasites (2011) (69)
- Foxp3 and IL-10 Expression Correlates with Parasite Burden in Lesional Tissues of Post Kala Azar Dermal Leishmaniasis (PKDL) Patients (2011) (68)
- Interferon (IFN)–γ, Tumor Necrosis Factor–α, Interleukin-6, and IFN-γ Receptor 1 Are the Major Immunological Determinants Associated with Post–Kala Azar Dermal Leishmaniasis (2006) (67)
- An approach for interlaboratory comparison of conventional and real-time PCR assays for diagnosis of human leishmaniasis. (2013) (62)
- Increased miltefosine tolerance in clinical isolates of Leishmania donovani is associated with reduced drug accumulation, increased infectivity and resistance to oxidative stress (2017) (59)
- Upregulation of surface proteins in Leishmania donovani isolated from patients of post kala-azar dermal leishmaniasis. (2006) (58)
- Visceral leishmaniasis, or kala azar (KA): high incidence of refractoriness to antimony is contributed by anthroponotic transmission via post-KA dermal leishmaniasis. (2006) (57)
- Application of loop-mediated isothermal amplification assay for the sensitive and rapid diagnosis of visceral leishmaniasis and post-kala-azar dermal leishmaniasis. (2013) (57)
- Elucidation of Cellular Mechanisms Involved in Experimental Paromomycin Resistance in Leishmania donovani (2014) (57)
- Miltefosine as an effective choice in the treatment of post‐kala‐azar dermal leishmaniasis (2011) (56)
- Genetically modified live attenuated parasites as vaccines for leishmaniasis. (2006) (53)
- Overexpression of histone H2A modulates drug susceptibility in Leishmania parasites. (2010) (53)
- Parasite detection in patients with post kala-azar dermal leishmaniasis in India: a comparison between molecular and immunological methods (2003) (52)
- Decline in Clinical Efficacy of Oral Miltefosine in Treatment of Post Kala-azar Dermal Leishmaniasis (PKDL) in India (2015) (52)
- Transcriptome analysis during the process of in vitro differentiation of Leishmania donovani using genomic microarrays (2007) (51)
- Evidence for Involvement of Th17 Type Responses in Post Kala Azar Dermal Leishmaniasis (PKDL) (2012) (50)
- Expression of DnaK and GroEL homologs in Leuconostoc esenteroides in response to heat shock, cold shock or chemical stress. (1995) (50)
- The application of gene expression microarray technology to kinetoplastid research. (2004) (49)
- Clinico-epidemiological analysis of Post kala-azar dermal leishmaniasis (PKDL) cases in India over last two decades: a hospital based retrospective study (2015) (49)
- Biomarkers of Safety and Immune Protection for Genetically Modified Live Attenuated Leishmania Vaccines Against Visceral Leishmaniasis – Discovery and Implications (2014) (48)
- Validation of a simple resazurin-based promastigote assay for the routine monitoring of miltefosine susceptibility in clinical isolates of Leishmania donovani (2013) (47)
- Biomarkers of antimony resistance: need for expression analysis of multiple genes to distinguish resistance phenotype in clinical isolates of Leishmania donovani (2012) (46)
- Nested PCR Assay for Detection of Leishmania donovani in Slit Aspirates from Post-Kala-Azar Dermal Leishmaniasis Lesions (2004) (44)
- Development of a rapid loop-mediated isothermal amplification assay for diagnosis and assessment of cure of Leishmania infection (2017) (43)
- Role of CD8+ T cells in protection against Leishmania donovani infection in healed Visceral Leishmaniasis individuals (2014) (43)
- Experimental Induction of Paromomycin Resistance in Antimony-Resistant Strains of L. donovani: Outcome Dependent on In Vitro Selection Protocol (2012) (43)
- In vitro susceptibility of Leishmania donovani to miltefosine in Indian visceral leishmaniasis. (2013) (42)
- Deletion of mitochondrial associated ubiquitin fold modifier protein Ufm1 in Leishmania donovani results in loss of β‐oxidation of fatty acids and blocks cell division in the amastigote stage (2012) (42)
- Long‐term efficacy of single‐dose radiofrequency‐induced heat therapy vs. intralesional antimonials for cutaneous leishmaniasis in India (2013) (41)
- Evaluation of localized and systemic immune responses in cutaneous leishmaniasis caused by Leishmania tropica: interleukin‐8, monocyte chemotactic protein‐1 and nitric oxide are major regulatory factors (2010) (41)
- In Vitro Evaluation of a Soluble Leishmania Promastigote Surface Antigen as a Potential Vaccine Candidate against Human Leishmaniasis (2014) (40)
- A simple and sensitive test for field diagnosis of post kala‐azar dermal leishmaniasis (2001) (39)
- Clinco-epidemiologic study of cutaneous leishmaniasis in Bikaner, Rajasthan, India. (2013) (39)
- Analysis of localized immune responses reveals presence of Th17 and Treg cells in cutaneous leishmaniasis due to Leishmania tropica (2013) (35)
- Comparative transcript expression analysis of miltefosine-sensitive and miltefosine-resistant Leishmania donovani (2014) (34)
- Correlation of parasitic load with interleukin-4 response in patients with cutaneous leishmaniasis due to Leishmania tropica. (2009) (33)
- Western blot analysis of humoral immune response to Leishmania donovani antigens in patients with post-kala-azar dermal leishmaniasis. (1999) (33)
- Short communication: Post‐kala‐azar dermal leishmaniasis – an appraisal (2007) (32)
- Evaluation of Enzyme-Linked Immunosorbent Assay for Diagnosis of Post-Kala-Azar Dermal Leishmaniasis with Crude or Recombinant k39 Antigen (2002) (31)
- Antimony-Resistant Clinical Isolates of Leishmania donovani Are Susceptible to Paromomycin and Sitamaquine (2011) (31)
- A Leishmania minicircle DNA footprint assay for sensitive detection and rapid speciation of clinical isolates (2008) (31)
- Reliable diagnosis of post‐kala‐azar dermal leishmaniasis (PKDL) using slit aspirate specimen to avoid invasive sampling procedures (2012) (30)
- Multilocus microsatellite typing reveals a genetic relationship but, also, genetic differences between Indian strains of Leishmania tropica causing cutaneous leishmaniasis and those causing visceral leishmaniasis (2014) (30)
- A novel semiquantitative fluorescence-based multiplex polymerase chain reaction assay for rapid simultaneous detection of bacterial and parasitic pathogens from blood. (2005) (30)
- DNA Polymorphism Assay Distinguishes Isolates of Leishmania donovani That Cause Kala-Azar from Those That Cause Post-Kala-Azar Dermal Leishmaniasis in Humans (2004) (30)
- Thermostabilization of protective antigen--the binding component of anthrax lethal toxin. (1996) (28)
- Correction: Decline in Clinical Efficacy of Oral Miltefosine in Treatment of Post Kala-azar Dermal Leishmaniasis (PKDL) in India (2015) (28)
- Pediatric cutaneous leishmaniasis in an endemic region in India. (2014) (28)
- Interferon (IFN)-gamma , tumor necrosis factor-alpha , interleukin-6, and IFN-gamma receptor 1 are the major immunological determinants associated with post-kala azar dermal leishmaniasis. (2006) (27)
- Tumour necrosis factor-alpha induces preferential expression of stress proteins in virulent promastigotes of Leishmania donovani. (1995) (26)
- Validation of SYBR green I based closed tube loop mediated isothermal amplification (LAMP) assay and simplified direct-blood-lysis (DBL)-LAMP assay for diagnosis of visceral leishmaniasis (VL) (2018) (26)
- Post-kala-azar dermal leishmaniasis (PKDL) developing after treatment of visceral leishmaniasis with amphotericin B and miltefosine (2009) (26)
- Evidence for involvement of TNFR1 and TIMPs in pathogenesis of post‐kala‐azar dermal leishmaniasis (2008) (25)
- Mitochondrial Associated Ubiquitin Fold Modifier-1 Mediated Protein Conjugation in Leishmania donovani (2011) (25)
- Circulating nitric oxide and C-reactive protein levels in Indian kala azar patients: correlation with clinical outcome. (2007) (23)
- Evaluation of cellular immunological responses in mono‐ and polymorphic clinical forms of post‐kala‐azar dermal leishmaniasis in India (2016) (22)
- Generation of growth arrested Leishmania amastigotes: a tool to develop live attenuated vaccine candidates against visceral leishmaniasis. (2014) (22)
- Gene deleted live attenuated Leishmania vaccine candidates against visceral leishmaniasis elicit pro-inflammatory cytokines response in human PBMCs (2016) (22)
- Diagnosis of visceral leishmaniasis: comparative potential of amastigote antigen, recombinant antigen and PCR (2002) (21)
- Potential of Direct Agglutination Test Based on Promastigote and Amastigote Antigens for Serodiagnosis of Post-Kala-Azar Dermal Leishmaniasis (2005) (20)
- Cutaneous leishmaniasis in Nepal: Leishmania major as a cause. (2008) (20)
- Indian mucosal leishmaniasis due to Leishmania donovani infection. (2008) (20)
- A patient presenting with diffuse cutaneous leishmaniasis (DCL) as a first indicator of HIV infection in India. (2011) (19)
- Heat, Oriental sore, and HIV (2011) (18)
- Heat-stress induced modulation of protein phosphorylation in virulent promastigotes of Leishmania donovani. (2000) (18)
- Oral miltefosine in the treatment of post‐kala‐azar dermal leishmaniasis (2007) (17)
- A retrospective study of intravenous sodium stibogluconate alone and in combinations with allopurinol, rifampicin, and an immunomodulator in the treatment of Indian post-kala-azar dermal leishmaniasis. (2010) (17)
- Differential expression of stress proteins in virulent and attenuated promastigotes of Leishmania donovani. (1994) (17)
- Leishmania donovani‐specific Ub‐related modifier‐1: an early endosome‐associated ubiquitin‐like conjugation in Leishmania donovani (2015) (16)
- Arbitrary-primed PCR for genomic fingerprinting and identification of differentially regulated genes in Indian isolates of Leishmania donovani. (2004) (16)
- Immunoblot analysis of the antibody response to antigens of Leishmania donovani in Indian kala-azar. (1999) (16)
- Transcriptome profiling identifies genes/pathways associated with experimental resistance to paromomycin in Leishmania donovani (2017) (16)
- Comparative in vivo expression of amastigote up regulated Leishmania genes in three different forms of Leishmaniasis. (2010) (15)
- Presence of anti-Lepp12 antibody: a marker for diagnostic and prognostic evaluation of visceral leishmaniasis. (2008) (15)
- Genetic typing reveals monomorphism between antimony sensitive and resistant Leishmania donovani isolates from visceral leishmaniasis or post kala-azar dermal leishmaniasis cases in India (2012) (15)
- Elevated levels of IgG3 and IgG4 subclass in paediatric cases of kala azar (2008) (15)
- Hypopigmented post‐kala‐azar dermal leishmaniasis (2008) (14)
- Evaluation of P‐glycoprotein expression in human oral oncogenesis: Correlation with clinicopathological features (1997) (13)
- Combination therapy with amphotericin-B and miltefosine for post-kala-azar dermal leishmaniasis: a preliminary report. (2014) (13)
- Nerve involvement in Indian post kala-azar dermal leishmaniasis. (2004) (13)
- Immune response following miltefosine therapy in a patient with post-kala-azar dermal leishmaniasis. (2008) (12)
- Unresponsive cutaneous leishmaniasis and HIV co-infection: report of three cases. (2011) (12)
- Genetic fingerprinting and identification of differentially expressed genes in isolates of Leishmania donovani from Indian patients of post-kala-azar dermal leishmaniasis (2007) (12)
- Serological and Molecular Analysis of Leishmania Infection in Healthy Individuals from Two Districts of West Bengal, India, Endemic for Visceral Leishmaniasis. (2017) (11)
- Assessing the Efficacy and Safety of Liposomal Amphotericin B and Miltefosine in Combination for Treatment of Post Kala-Azar Dermal Leishmaniasis. (2019) (11)
- Post-kala-azar dermal leishmaniasis - : an appraisal (2007) (11)
- Possible role of the 34-kilodalton hyaluronic acid-binding protein in visceral Leishmaniasis. (1999) (8)
- Antigenaemia and antibody response to Leishmania donovani stage-specific antigens and rk39 antigen in human immunodeficiency virus-infected patients (2003) (8)
- Increased parasite surface antigen-2 expression in clinical isolates of Leishmania donovani augments antimony resistance. (2013) (7)
- Artemisinin-resistant Leishmania parasite modulates host cell defense mechanism and exhibits altered expression of unfolded protein response genes (2019) (7)
- Evaluation of Enzyme-Linked Immunosorbent Assay for Diagnosis of Post-Kala-Azar Dermal Leishmaniasis with Crude or Recombinant k 39 Antigen (2002) (6)
- Rapid & reliable diagnostic tests for visceral leishmaniasis. (2005) (6)
- Real-Time Fluorimetry Loop-Mediated Isothermal Amplification for Diagnosis of Leishmaniasis and as a Tool for Assessment of Cure for Post-Kala-Azar Dermal Leishmaniasis. (2021) (5)
- Lipase Precursor-Like Protein Promotes Miltefosine Tolerance in Leishmania donovani by Enhancing Parasite Infectivity and Eliciting Anti-inflammatory Responses in Host Macrophages (2018) (5)
- Interferon ( IFN ) – g , Tumor Necrosis Factor – a , Interleukin-6 , and IFN-g Receptor 1 Are the Major Immunological Determinants Associated with Post – Kala Azar Dermal Leishmaniasis (2006) (5)
- Revisiting the role of the slit-skin smear in the diagnosis of Indian post-kala-azar dermal leishmaniasis (2018) (4)
- A novel signal sequence negative multimeric glycosomal protein required for cell cycle progression of Leishmania donovani parasites. (2018) (4)
- Visceral leishmaniasis - current treatments and needs. (2013) (4)
- Rapid Multiplex Loop-Mediated Isothermal Amplification (m-LAMP) Assay for Differential Diagnosis of Leprosy and Post-Kala-Azar Dermal Leishmaniasis. (2021) (4)
- L-alanine: 4,5-dioxovalerate transaminase in Leishmania donovani that differs from mammalian enzyme. (1995) (3)
- Diagnosis of visceral leishmaniasis: comparative potential of amastigote antigen, recombinant antigen and PCR. (2002) (3)
- Advancement in Molecular Diagnosis of Post Kala-Azar Dermal Leishmaniasis (2020) (3)
- Containing Post Kala-Azar Dermal Leishmaniasis (PKDL): Pre-requisite for Sustainable Elimination of Visceral Leishmaniasis (VL) from South Asia (2016) (3)
- Immunity to protozoan parasite infection (PP-002) (2010) (3)
- A Leishmania-specific gene upregulated at the amastigote stage is crucial for parasite survival (2018) (3)
- Indian erythrodermic postkala-azar dermal leishmaniasis (2017) (3)
- Shave excision as an adjunct to the therapy of a rhinophyma-like complication in post-kala-azar dermal leishmaniasis. (1999) (3)
- Development of a novel loop-mediated isothermal amplification assay for rapid detection of Mycobacterium leprae in clinical samples. (2021) (3)
- Genomic and Transcriptomic Analysis for Identification of Genes and Interlinked Pathways Mediating Artemisinin Resistance in Leishmania donovani (2020) (3)
- Post‐kala‐azar dermal leishmaniasis in HIV‐coinfected individuals: problems in diagnosis and treatment (2015) (2)
- Utility of Blood as the Clinical Specimen for the Molecular Diagnosis of Post-Kala-Azar Dermal Leishmaniasis (2021) (2)
- An unusual presentation of post-kala-azar dermal leishmaniasis (2007) (2)
- Analysis of localized immune responses reveals presence of Th17 and Treg cells in cutaneous leishmaniasis due to Leishmania tropica (2013) (2)
- Methods to Evaluate the Preclinical Safety and Immunogenicity of Genetically Modified Live-Attenuated Leishmania Parasite Vaccines. (2016) (2)
- Proteomic Analysis of Leishmania donovani Membrane Components Reveals the Role of Activated Protein C Kinase in Host-Parasite Interaction (2021) (2)
- Identification of protein biomarkers of attenuation and immunogenicity of centrin or p27 gene deleted live vaccine candidates of Leishmania against visceral leishmaniasis. (2022) (1)
- Role of stress proteins in Leishmania (1998) (1)
- In vitro MIL susceptibility of parasite isolates from cured (n = 7) and relapsed (n = 6) PKDL patients. (2015) (1)
- Proteomic analysis of membrane proteins involved in Leishmania ‐ macrophage interaction (2020) (1)
- Reply to comment on: Cutaneous leishmaniasis in Nepal: Leishmania major as a cause (2008) (1)
- Biomarkers of antimony resistance: need for expression analysis of multiple genes to distinguish resistance phenotype in clinical isolates of Leishmania donovani (2012) (0)
- In vitro Drug Interactions of Epicatechin Gallate and Ethyl Gallate with Non Beta-Lactam Antibiotics in Methicillin Resistant and Methicillin sensitive Staphylococcus aureus (2009) (0)
- Multilocus microsatellite typing reveals a genetic relationship but, also, genetic differences between Indian strains of Leishmania tropica causing cutaneous leishmaniasis and those causing visceral leishmaniasis (2014) (0)
- Validation of a simple resazurin-based promastigote assay for the routine monitoring of miltefosine susceptibility in clinical isolates of Leishmania donovani (2012) (0)
- Differential expression of heat shock proteins in virulent and attenuated strains of Leishmania donovani. (1994) (0)
- Part One Disease Burden , Current Treatments , Medical Needs , and Strategic Approaches (2013) (0)
- Evidence for Accumulation of T Regulatory Cells in Lesion Tissue of Post Kala-azar Dermal Leishmaniasis (PKDL) Patients: A Marker for Distinct Pathology (2010) (0)
- Comparative transcript expression analysis of miltefosine-sensitive and miltefosine-resistant Leishmania donovani (2014) (0)
- Interaction of novel proteins, centrin4 and protein of centriole in Leishmania parasite and their effects on the parasite growth. (2023) (0)
- Title: Antimony resistant clinical isolates of Leishmania donovani are susceptible to (2011) (0)
- and Elicit Long-Term Protective Immunity Nonpathogenic Gene Knockout Parasites Are p27 Leishmania donovani Live Attenuated (2013) (0)
- Case definition for recording treatment outcome of PKDL patients. (2015) (0)
- Differential expression of parasite surface antigen-2 (PSA-2) in antimony resistant and sensitive clinical isolates of Leishmania donovani (2014) (0)
- Genetic typing reveals monomorphism between antimony sensitive and resistant Leishmania donovani isolates from visceral leishmaniasis or post kala-azar dermal leishmaniasis cases in India (2012) (0)
- Elucidation of role of an acetyltransferase like protein in paromomycin resistance in Leishmania donovani using in silico and in vitro approaches (2020) (0)
- Development of a novel loop-mediated isothermal amplification assay for rapid detection of Mycobacterium leprae in clinical samples. (2021) (0)
- A PKDL patient (Case 11, table no. 3) that relapsed after MIL treatment and was subsequently cured with AmB. (2015) (0)
- Diagnosis of visceral leishmaniasis: developments over the last decade (2011) (0)
- A Leishmania-specific gene upregulated at the amastigote stage is crucial for parasite survival (2018) (0)
- Novel strategies to attenuate Leishmania donovani pathogenesis. (2000) (0)
- Genome-wide analysis reveals allelic variation and chromosome copy number variation in paromomycin-resistant Leishmania donovani (2022) (0)
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