Zhan Qimin
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Chinese molecular oncologist
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Zhan Qiminbiology Degrees
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Molecular Biology
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Biology
Zhan Qimin's Degrees
- Bachelors Biology Peking University
- Masters Molecular Biology Fudan University
- PhD Molecular Oncology Tsinghua University
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Why Is Zhan Qimin Influential?
(Suggest an Edit or Addition)According to Wikipedia, Zhan Qimin is a Chinese molecular oncologist currently serving as director of Peking University Medicine Department, executive vice-president of Peking University and dean of Peking University Shenzhen Graduate School. He is a member of the Communist Party of China.
Zhan Qimin's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia (1992) (3220)
- Identification of genomic alterations in oesophageal squamous cell cancer (2014) (863)
- Association with Cdc2 and inhibition of Cdc2/Cyclin B1 kinase activity by the p53-regulated protein Gadd45 (1999) (503)
- Genomic instability in Gadd45a-deficient mice (1999) (489)
- Genomic Analyses Reveal Mutational Signatures and Frequently Altered Genes in Esophageal Squamous Cell Carcinoma (2015) (272)
- Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations (2011) (266)
- Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions (2012) (227)
- Human In vivo Radiation-Induced Biomarkers (2004) (218)
- The GADD45 Inhibition of Cdc2 Kinase Correlates with GADD45-mediated Growth Suppression* (2000) (217)
- The p53-dependent γ-Ray Response of GADD45 (1994) (213)
- The mismatch repair system is required for S-phase checkpoint activation (2003) (209)
- ATF3 induction following DNA damage is regulated by distinct signaling pathways and over-expression of ATF3 protein suppresses cells growth (2002) (199)
- GADD45-induced cell cycle G2-M arrest associates with altered subcellular distribution of cyclin B1 and is independent of p38 kinase activity (2002) (197)
- Gadd45a, a p53- and BRCA1-regulated stress protein, in cellular response to DNA damage. (2005) (196)
- Overexpression of Aurora-A Contributes to Malignant Development of Human Esophageal Squamous Cell Carcinoma (2004) (172)
- Long non‐coding RNA gadd7 interacts with TDP‐43 and regulates Cdk6 mRNA decay (2012) (169)
- Tumor Suppressor p53 Can Participate in Transcriptional Induction of the GADD45 Promoter in the Absence of Direct DNA Binding (1998) (165)
- Mammalian GADD34, an Apoptosis- and DNA Damage-inducible Gene* (1997) (163)
- Long noncoding RNA HULC modulates the phosphorylation of YB‐1 through serving as a scaffold of extracellular signal–regulated kinase and YB‐1 to enhance hepatocarcinogenesis (2016) (154)
- Genomic analysis of oesophageal squamous-cell carcinoma identifies alcohol drinking-related mutation signature and genomic alterations (2017) (146)
- BRCA1 Regulates GADD45 through Its Interactions with the OCT-1 and CAAT Motifs* (2002) (138)
- Disruption of xCT inhibits cancer cell metastasis via the caveolin-1/β-catenin pathway (2009) (135)
- Joint analysis of three genome-wide association studies of esophageal squamous cell carcinoma in Chinese populations (2014) (133)
- RRLC-MS/MS-based metabonomics combined with in-depth analysis of metabolic correlation network: finding potential biomarkers for breast cancer. (2009) (130)
- Novel MUC1 Aptamer Selectively Delivers Cytotoxic Agent to Cancer Cells In Vitro (2012) (126)
- Manganese Superoxide Dismutase (SOD2) Inhibits Radiation-Induced Apoptosis by Stabilization of the Mitochondrial Membrane (2002) (123)
- A PLK1 kinase inhibitor enhances the chemosensitivity of cisplatin by inducing pyroptosis in oesophageal squamous cell carcinoma (2019) (121)
- Transcription factors Oct-1 and NF-YA regulate the p53-independent induction of the GADD45 following DNA damage (2001) (117)
- Gadd45a Expression Induces Bim Dissociation from the Cytoskeleton and Translocation to Mitochondria (2005) (111)
- Enriched CD44(+)/CD24(-) population drives the aggressive phenotypes presented in triple-negative breast cancer (TNBC). (2014) (111)
- Accessing Genetic Information with Liquid Biopsies. (2015) (104)
- Whole-Genome Sequencing Reveals Diverse Models of Structural Variations in Esophageal Squamous Cell Carcinoma (2016) (104)
- DNA methylation-mediated repression of miR-886-3p predicts poor outcome of human small cell lung cancer. (2013) (103)
- Identification of Several Human Homologs of Hamster DNA Damage-inducible Transcripts (1997) (98)
- Global and Targeted Metabolomics of Esophageal Squamous Cell Carcinoma Discovers Potential Diagnostic and Therapeutic Biomarkers* (2013) (95)
- Integrated ionization approach for RRLC-MS/MS-based metabonomics: finding potential biomarkers for lung cancer. (2010) (95)
- BRCA1 activation of the GADD45 promoter (2000) (95)
- Gadd45a contributes to p53 stabilization in response to DNA damage (2003) (89)
- IKKβ programs to turn on the GADD45α–MKK4–JNK apoptotic cascade specifically via p50 NF-κB in arsenite response (2006) (89)
- Overexpression of cyclin B1 in human esophageal squamous cell carcinoma cells induces tumor cell invasive growth and metastasis. (2008) (89)
- Whole-genome sequencing of 508 patients identifies key molecular features associated with poor prognosis in esophageal squamous cell carcinoma (2020) (88)
- Myc suppresses induction of the growth arrest genes gadd34, gadd45, and gadd153 by DNA-damaging agents (1998) (88)
- Activation of the transcription factor Oct-1 in response to DNA damage. (2000) (85)
- Multi-region sequencing unveils novel actionable targets and spatial heterogeneity in esophageal squamous cell carcinoma (2019) (85)
- Overexpression of human pituitary tumor transforming gene (hPTTG), is regulated by β‐catenin /TCF pathway in human esophageal squamous cell carcinoma (2005) (80)
- Overexpression of EB1 in human esophageal squamous cell carcinoma (ESCC) may promote cellular growth by activating β-catenin/TCF pathway (2005) (80)
- Immune recognition of cyclin B1 as a tumor antigen is a result of its overexpression in human tumors that is caused by non-functional p53. (2002) (79)
- Conditional mutation of Pkd2 causes cystogenesis and upregulates beta-catenin. (2009) (78)
- Induction of BCL2 family member MCL1 as an early response to DNA damage (1997) (78)
- Involvement of the MAP kinase pathways in induction of GADD45 following UV radiation. (2001) (70)
- Significance of COX-2 expression in human esophageal squamous cell carcinoma. (2006) (66)
- The central region of Gadd45 is required for its interaction with p21/WAF1. (2000) (66)
- B23 Regulates GADD45a Nuclear Translocation and Contributes to GADD45a-induced Cell Cycle G2-M Arrest* (2005) (66)
- Gadd45a Suppresses Tumor Angiogenesis via Inhibition of the mTOR/STAT3 Protein Pathway* (2013) (66)
- Involvement of S100A14 Protein in Cell Invasion by Affecting Expression and Function of Matrix Metalloproteinase (MMP)-2 via p53-dependent Transcriptional Regulation* (2012) (65)
- PPARγ ligands inhibit cholangiocarcinoma cell growth through p53‐dependent GADD45 and p21WAF1/Cip1 pathway (2003) (63)
- Liquid chromatography-tandem mass spectrometry-based plasma metabonomics delineate the effect of metabolites' stability on reliability of potential biomarkers. (2013) (62)
- Inhibition of SOX17 by microRNA 141 and methylation activates the WNT signaling pathway in esophageal cancer. (2012) (62)
- Activation of Gadd34 by diverse apoptotic signals and suppression of its growth inhibitory effects by apoptotic inhibitors (2001) (61)
- Long noncoding RNA PCAT1, a novel serum-based biomarker, enhances cell growth by sponging miR-326 in oesophageal squamous cell carcinoma (2019) (60)
- Gadd45a Interacts with Aurora-A and Inhibits Its Kinase Activity* (2006) (58)
- Reduced MTA1 Expression by RNAi Inhibits in Vitro Invasion and Migration of Esophageal Squamous Cell Carcinoma Cell Line (2006) (58)
- Genomic analyses reveal FAM84B and the NOTCH pathway are associated with the progression of esophageal squamous cell carcinoma (2016) (57)
- Epigenetic regulation of DACT2, a key component of the Wnt signalling pathway in human lung cancer (2013) (57)
- Genomic profiling of 766 cancer‐related genes in archived esophageal normal and carcinoma tissues (2008) (57)
- Tumor Suppressor p53 Is a Negative Regulator in Thyroid Hormone Receptor Signaling Pathways* (1997) (55)
- Overexpression of Stefin A in Human Esophageal Squamous Cell Carcinoma Cells Inhibits Tumor Cell Growth, Angiogenesis, Invasion, and Metastasis (2005) (54)
- Inhibitory effect of Bcl-2 on p53-mediated transactivation following genotoxic stress (1999) (54)
- Role for Kruppel-like factor 4 in determining the outcome of p53 response to DNA damage. (2009) (53)
- Caspase-3 mediated cleavage of BRCA1 during UV-induced apoptosis (2002) (53)
- PTTG overexpression promotes lymph node metastasis in human esophageal squamous cell carcinoma. (2009) (50)
- A novel TP53 pathway influences the HGS-mediated exosome formation in colorectal cancer (2016) (48)
- Electric fields generated by synchronized oscillations of microtubules, centrosomes and chromosomes regulate the dynamics of mitosis and meiosis (2012) (48)
- Administration of PUMA adenovirus increases the sensitivity of esophageal cancer cells to anticancer drugs (2006) (44)
- Downregulation of survivin by RNAi inhibits the growth of esophageal carcinoma cells (2005) (42)
- Cell Cycle-dependent Expression of Centrosomal Ninein-like Protein in Human Cells Is Regulated by the Anaphase-promoting Complex* (2007) (42)
- Quiescence and attenuated DNA damage response promote survival of esophageal cancer stem cells (2012) (42)
- Feed-Forward Reciprocal Activation of PAFR and STAT3 Regulates Epithelial-Mesenchymal Transition in Non-Small Cell Lung Cancer. (2015) (42)
- MicroRNA‐548j functions as a metastasis promoter in human breast cancer by targeting Tensin1 (2016) (41)
- Prognostic significance of MCM7 expression in the bronchial brushings of patients with non-small cell lung cancer (NSCLC). (2012) (40)
- Transcriptional Downregulation of miR-4306 serves as a New Therapeutic Target for Triple Negative Breast Cancer (2019) (39)
- Osthole inhibits the PI3K/AKT signaling pathway via activation of PTEN and induces cell cycle arrest and apoptosis in esophageal squamous cell carcinoma. (2018) (38)
- Epigenetic changes and functional study of HOXA11 in human gastric cancer. (2015) (38)
- Centrosomal Nlp is an oncogenic protein that is gene-amplified in human tumors and causes spontaneous tumorigenesis in transgenic mice. (2010) (38)
- Receptor Interactive Protein Kinase 3 Promotes Cisplatin-Triggered Necrosis in Apoptosis-Resistant Esophageal Squamous Cell Carcinoma Cells (2014) (37)
- Autoreactive T Cells and Chronic Fungal Infection Drive Esophageal Carcinogenesis. (2017) (37)
- A MicroRNA Signature Predicts Survival in Early Stage Small-Cell Lung Cancer Treated with Surgery and Adjuvant Chemotherapy (2014) (37)
- Aurora-A interacts with Cyclin B1 and enhances its stability. (2009) (36)
- Methylation of TFPI-2 is an early event of esophageal carcinogenesis. (2012) (35)
- Overexpression of cyclin B1 antagonizes chemotherapeutic-induced apoptosis through PTEN/Akt pathway in human esophageal squamous cell carcinoma cells (2013) (35)
- The subcellular distribution and function of MTA1 in cancer differentiation (2014) (34)
- Downregulation of miR-503 Promotes ESCC Cell Proliferation, Migration, and Invasion by Targeting Cyclin D1 (2017) (34)
- Platelet-activating factor receptor-mediated PI3K/AKT activation contributes to the malignant development of esophageal squamous cell carcinoma (2015) (34)
- Migfilin Protein Promotes Migration and Invasion in Human Glioma through Epidermal Growth Factor Receptor-mediated Phospholipase C-γ and STAT3 Protein Signaling Pathways* (2012) (33)
- Dasatinib enhances cisplatin sensitivity in human esophageal squamous cell carcinoma (ESCC) cells via suppression of PI3K/AKT and Stat3 pathways. (2015) (33)
- Methylation of DACT2 accelerates esophageal cancer development by activating Wnt signaling (2016) (33)
- Assessment of data pre-processing methods for LC-MS/MS-based metabolomics of uterine cervix cancer. (2013) (32)
- Role of Smac in Determining the Chemotherapeutic Response of Esophageal Squamous Cell Carcinoma (2011) (32)
- miR-503-3p promotes epithelial-mesenchymal transition in breast cancer by directly targeting SMAD2 and E-cadherin. (2017) (32)
- Global metabolomics reveals potential urinary biomarkers of esophageal squamous cell carcinoma for diagnosis and staging (2016) (31)
- Liver tumour immune microenvironment subtypes and neutrophil heterogeneity (2022) (31)
- Molecular predictors of brain metastasis-related microRNAs in lung adenocarcinoma (2019) (31)
- Silencing DACH1 Promotes Esophageal Cancer Growth by Inhibiting TGF-β Signaling (2014) (31)
- Adenoviral‐mediated gene transfer of Gadd45a results in suppression by inducing apoptosis and cell cycle arrest in pancreatic cancer cell (2009) (30)
- Methylation of CHFR sensitizes esophageal squamous cell cancer to docetaxel and paclitaxel (2015) (29)
- PPARgamma ligands inhibit cholangiocarcinoma cell growth through p53-dependent GADD45 and p21 pathway. (2003) (29)
- Activation of Aurora A kinase increases YAP stability via blockage of autophagy (2019) (28)
- Silencing NKD2 by Promoter Region Hypermethylation Promotes Esophageal Cancer Progression by Activating Wnt Signaling (2016) (28)
- Enhanced Expression of miR-425 Promotes Esophageal Squamous Cell Carcinoma Tumorigenesis by Targeting SMAD2. (2015) (28)
- Gadd45a regulates β-catenin distribution and maintains cell–cell adhesion/contact (2007) (28)
- BRCA1 Interaction of Centrosomal Protein Nlp Is Required for Successful Mitotic Progression*♦ (2009) (28)
- Ad-PUMA sensitizes drug-resistant choriocarcinoma cells to chemotherapeutic agents. (2007) (27)
- The chromosome 11q13.3 amplification associated lymph node metastasis is driven by miR-548k through modulating tumor microenvironment (2018) (27)
- Piccolo mediates EGFR signaling and acts as a prognostic biomarker in esophageal squamous cell carcinoma (2017) (27)
- Silencing NKD2 by promoter region hypermethylation promotes gastric cancer invasion and metastasis by up-regulating SOX18 in human gastric cancer (2015) (27)
- MiR-423-5p in brain metastasis: potential role in diagnostics and molecular biology (2018) (26)
- OncoBase: a platform for decoding regulatory somatic mutations in human cancers (2018) (26)
- TRAP1 shows clinical significance and promotes cellular migration and invasion through STAT3/MMP2 pathway in human esophageal squamous cell cancer. (2014) (26)
- Stable knockdown of Aurora-A by vector-based RNA interference in human esophageal squamous cell carcinoma cell line inhibits tumor cell proliferation, invasion and enhances apoptosis (2009) (25)
- Electric oscillation and coupling of chromatin regulate chromosome packaging and transcription in eukaryotic cells (2012) (25)
- Gadd45a regulates hematopoietic stem cell stress responses in mice. (2014) (25)
- 5-Aza-2'-deoxycytidine induces retinoic acid receptor-beta(2) demethylation and growth inhibition in esophageal squamous carcinoma cells. (2005) (25)
- Loss of Bicc1 impairs tubulomorphogenesis of cultured IMCD cells by disrupting E-cadherin-based cell-cell adhesion. (2010) (25)
- Epigenetic silencing BCL6B induced colorectal cancer proliferation and metastasis by inhibiting P53 signaling. (2015) (24)
- Nicotine Activates YAP1 through nAChRs Mediated Signaling in Esophageal Squamous Cell Cancer (ESCC) (2014) (23)
- Development of a metabolic pathway-based pseudo-targeted metabolomics method using liquid chromatography coupled with mass spectrometry. (2019) (23)
- Glutathione peroxidase 4‐dependent glutathione high‐consumption drives acquired platinum chemoresistance in lung cancer‐derived brain metastasis (2021) (23)
- The diacylglycerol kinase α (DGKα)/Akt/NF-κB feedforward loop promotes esophageal squamous cell carcinoma (ESCC) progression via FAK-dependent and FAK-independent manner (2018) (22)
- Increased expression of Nlp, a potential oncogene in ovarian cancer, and its implication in carcinogenesis. (2008) (22)
- Preventing BRCA1/ZBRK1 repressor complex binding to the GOT2 promoter results in accelerated aspartate biosynthesis and promotion of cell proliferation (2019) (22)
- Cystogenesis in ARPKD results from increased apoptosis in collecting duct epithelial cells of Pkhd1 mutant kidneys. (2011) (22)
- Kindlin-2 interacts with β-catenin and YB-1 to enhance EGFR transcription during glioma progression (2016) (22)
- Mutant TP53 G245C and R273H promote cellular malignancy in esophageal squamous cell carcinoma (2018) (22)
- BRCA1 regulates caveolin-1 expression and inhibits cell invasiveness. (2008) (22)
- BAG2 is a target of the c-Myc gene and is involved in cellular senescence via the p21(CIP1) pathway. (2012) (21)
- Downregulation of &bgr;‐arrestin 1 suppresses glioblastoma cell malignant progression vis inhibition of Src signaling (2017) (21)
- Flotillin1 promotes EMT of human small cell lung cancer via TGF-β signaling pathway (2018) (21)
- Metformin suppresses the esophageal carcinogenesis in rats treated with NMBzA through inhibiting AMPK/mTOR signaling pathway. (2018) (21)
- Gadd45a inhibits cell migration and invasion by altering the global RNA expression (2012) (21)
- Methylation of TMEM176A is an independent prognostic marker and is involved in human colorectal cancer development (2017) (21)
- RASSF10 suppresses hepatocellular carcinoma growth by activating P53 signaling and methylation of RASSF10 is a docetaxel resistant marker (2015) (20)
- Establishment of a new OSCC cell line derived from OLK and identification of malignant transformation-related proteins by differential proteomics approach (2015) (20)
- RASSF10 suppresses colorectal cancer growth by activating P53 signaling and sensitizes colorectal cancer cell to docetaxel (2015) (20)
- Targeting hyperactivated DNA-PKcs by KU0060648 inhibits glioma progression and enhances temozolomide therapy via suppression of AKT signaling (2016) (19)
- GADD45A inhibits autophagy by regulating the interaction between BECN1 and PIK3C3 (2015) (19)
- Differentiation-associated genes regulated by TPA-induced c-Jun expression via a PKC/JNK pathway in KYSE450 cells. (2006) (18)
- Chromatin modifier MTA1 regulates mitotic transition and tumorigenesis by orchestrating mitotic mRNA processing (2020) (18)
- KDM4C, a H3K9me3 Histone Demethylase, is Involved in the Maintenance of Human ESCC-Initiating Cells by Epigenetically Enhancing SOX2 Expression1 (2016) (18)
- The roles of RRP15 in nucleolar formation, ribosome biogenesis and checkpoint control in human cells (2017) (18)
- Methylation of ZNF331 Promotes Cell Invasion and Migration in Human Esophageal Cancer. (2015) (18)
- Long Noncoding RNA VESTAR Regulates Lymphangiogenesis and Lymph Node Metastasis of Esophageal Squamous Cell Carcinoma by Enhancing VEGFC mRNA Stability (2021) (18)
- High expression of HSP90 is associated with poor prognosis in patients with colorectal cancer (2019) (17)
- The role of centrosomal Nlp in the control of mitotic progression and tumourigenesis (2011) (17)
- Ninein-like protein is overexpressed in head and neck squamous cell carcinoma and contributes to cancer growth and resistance to apoptosis. (2009) (17)
- Aurora B Interaction of Centrosomal Nlp Regulates Cytokinesis* (2010) (16)
- Overexpression of centrosomal protein Nlp confers breast carcinoma resistance to paclitaxel (2012) (16)
- CDX2 serves as a Wnt signaling inhibitor and is frequently methylated in lung cancer (2012) (16)
- FAT1, a direct transcriptional target of E2F1, suppresses cell proliferation, migration and invasion in esophageal squamous cell carcinoma (2019) (16)
- Nuclear genome-derived circular RNA circPUM1 localizes in mitochondria and regulates oxidative phosphorylation in esophageal squamous cell carcinoma (2022) (16)
- Epigenetic silencing of RASSF10 promotes tumor growth in esophageal squamous cell carcinoma. (2014) (16)
- Bridging the GP gap: nurse practitioners in China (2019) (15)
- Aurora‐A enhances malignant development of esophageal squamous cell carcinoma (ESCC) by phosphorylating β‐catenin (2015) (15)
- Membranous NOX5-derived ROS oxidizes and activates local Src to promote malignancy of tumor cells (2020) (15)
- MTA1 regulates higher‐order chromatin structure and histone H1‐chromatin interaction in‐vivo (2015) (15)
- Mutually exclusive mutations in NOTCH1 and PIK3CA associated with clinical prognosis and chemotherapy responses of esophageal squamous cell carcinoma in China (2015) (15)
- Cdc2/cyclin B1 regulates centrosomal Nlp proteolysis and subcellular localization (2010) (13)
- Antitumor Effect of Periplocin in TRAIL‐Resistant gastric cancer cells via upregulation of death receptor through activating ERK1/2‐EGR1 pathway (2019) (13)
- Allelic imbalance of chromosome 1q in esophageal squamous cell carcinomas from China: a novel region of allelic loss and significant association with differentiation. (2005) (13)
- A GRN Autocrine-Dependent FAM135B/AKT/mTOR Feedforward Loop Promotes Esophageal Squamous Cell Carcinoma Progression (2020) (12)
- Focal adhesion kinase (FAK) inhibitor‐defactinib suppresses the malignant progression of human esophageal squamous cell carcinoma (ESCC) cells via effective blockade of PI3K/AKT axis and downstream molecular network (2020) (12)
- Chromosome analysis of esophageal squamous cell carcinoma cell line KYSE 410-4 by repetitive multicolor fluorescence in situ hybridization. (2008) (12)
- Long non-coding RNA SMASR inhibits the EMT by negatively regulating TGF-β/Smad signaling pathway in lung cancer (2021) (11)
- Evaluation of ER-α, ER-β1 and ER-β2 expression and correlation with clinicopathologic factors in invasive luminal subtype breast cancers (2012) (11)
- MTA1 promotes tumorigenesis and development of esophageal squamous cell carcinoma via activating the MEK/ERK/p90RSK signaling pathway. (2019) (11)
- Lyn regulates the cell death response to ultraviolet radiation through c-Jun N terminal kinase-dependent Fas ligand activation. (2003) (11)
- MicroRNA-548 j Functions as a Metastasis Promoter in Human Breast Cancer by Targeting Tensin 1 Running title : miR-548 j promotes breast cancer metastasis (2016) (11)
- Suppression of hepatocarcinoma model in vitro and in vivo by ECRG2 delivery using adenoviral vector (2012) (11)
- Cdk phosphorylation licenses Kif4A chromosome localization required for early mitotic progression (2018) (10)
- p53 functional activation is independent of its genotype in five esophageal squamous cell carcinoma cell lines (2010) (10)
- Telomeric epigenetic response mediated by Gadd45a regulates stem cell aging and lifespan (2018) (10)
- Exome sequencing identifies new somatic alterations and mutation patterns of tongue squamous cell carcinoma in a Chinese population (2020) (10)
- PFKP is transcriptionally repressed by BRCA1/ZBRK1 and predicts prognosis in breast cancer (2020) (9)
- Long non‐coding RNA LOC100133669 promotes cell proliferation in oesophageal squamous cell carcinoma (2020) (9)
- IQGAP1 interacts with Aurora-A and enhances its stability and its role in cancer. (2012) (9)
- A Single-Cell Immune Atlas of Triple Negative Breast Cancer Reveals Novel Immune Cell Subsets (2019) (9)
- MTA1 downregulation inhibits malignant potential in a small cell lung cancer cell line. (2015) (9)
- Overexpression of OLC1 Promotes Tumorigenesis of Human Esophageal Squamous Cell Carcinoma (2014) (8)
- Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl‐2/caspase‐3 pathway (2021) (8)
- BAALC‐AS1/G3BP2/c‐Myc feedback loop promotes cell proliferation in esophageal squamous cell carcinoma (2021) (8)
- A Comprehensive Analysis of Alterations in DNA Damage Repair Pathways Reveals a Potential Way to Enhance the Radio-Sensitivity of Esophageal Squamous Cell Cancer (2020) (8)
- APC/C-CDH1-regulated IDH3β coordinates with the cell cycle to promote cell proliferation. (2019) (8)
- NOX5 mediates the crosstalk between tumor cells and cancer‐associated fibroblasts via regulating cytokine network (2021) (8)
- Long non-coding RNA gadd 7 interacts with TDP-43 and regulates Cdk 6 mRNA decay (2012) (8)
- Migfilin promotes migration and invasion in glioma by driving EGFR and MMP-2 signalings: A positive feedback loop regulation. (2017) (8)
- MiR-205 inhibits the invasion and migration of esophageal squamous cell carcinoma by modulating SMAD1 expression (2014) (7)
- Aurora-A Interacts with AP-2α and Down Regulates Its Transcription Activity (2011) (7)
- GADD45G Interacts with E-cadherin to Suppress the Migration and Invasion of Esophageal Squamous Cell Carcinoma (2019) (7)
- MAGE‐C3 promotes cancer metastasis by inducing epithelial‐mesenchymal transition and immunosuppression in esophageal squamous cell carcinoma (2021) (6)
- Genomic Analyses Reveal Mutational Signatures and Frequently Altered Genes in Esophageal Squamous Cell Carcinoma (2020) (6)
- BRCA1 regulates transforming growth factor‐β (TGF‐β1) signaling through Gadd45a by enhancing the protein stability of Smad4 (2015) (6)
- The m6A-induced lncRNA CASC8 promotes proliferation and chemoresistance via upregulation of hnRNPL in esophageal squamous cell carcinoma (2022) (6)
- Nlp promotes autophagy through facilitating the interaction of Rab7 and FYCO1 (2021) (6)
- Dynamic analysis of DNA damage induced miRNAs in colon cancer cells (2014) (5)
- A feasibility study on gene therapy of pancreatic carcinoma with Ad-PUMA (2012) (5)
- Genomic and epigenomic evolution of acquired resistance to combination therapy in esophageal squamous cell carcinoma (2021) (5)
- Down-modulation of Notch1 expression in cervical cancer is associated with HPV-induced carcinogenesis (2009) (5)
- Chrysin serves as a novel inhibitor of DGKα/FAK interaction to suppress the malignancy of esophageal squamous cell carcinoma (ESCC) (2020) (5)
- miR-875-5p exerts tumor-promoting function via down-regulation of CAPZA1 in esophageal squamous cell carcinoma (2021) (5)
- Cell cycle and tumor translational medicine (2014) (5)
- Co-expression network analysis identifies key modules and hub genes implicated in esophageal squamous cell cancer progression (2020) (4)
- Identification of second primary tumors from lung metastases in patients with esophageal squamous cell carcinoma using whole-exome sequencing (2020) (4)
- Effects of esophageal cancer cell-derived exosomes on cancer cell migration and invasion and its mechanism research (2017) (4)
- Bioinformatic exploration of MTA1-regulated gene networks in colon cancer (2016) (4)
- Exploring the role of microRNAs in tumorigenesis (2014) (4)
- Defect of SLC38A3 promotes epithelial-mesenchymal transition and predicts poor prognosis in esophageal squamous cell carcinoma (2020) (4)
- Crystal structure of human Gadd45 reveals an active dimer (2011) (4)
- Strategic Study on Medical Education and Personnel Training in China (2019) (4)
- Gut microbiota-mediated nucleotide synthesis attenuates the response to neoadjuvant chemoradiotherapy in rectal cancer. (2022) (4)
- The noncoding function of NELFA mRNA promotes the development of oesophageal squamous cell carcinoma by regulating the Rad17‐RFC2‐5 complex (2019) (3)
- [Expression of fascin and cytokeratin 14 in esophageal squamous cell carcinoma]. (2007) (3)
- Author Correction: Multi-region sequencing unveils novel actionable targets and spatial heterogeneity in esophageal squamous cell carcinoma (2020) (3)
- Correction: Molecular predictors of brain metastasis-related microRNAs in lung adenocarcinoma (2020) (3)
- Tumor-associated macrophage (TAM)-derived CCL22 induces FAK addiction in esophageal squamous cell carcinoma (ESCC) (2022) (3)
- Characterization of somatic structural variations in 528 Chinese individuals with Esophageal squamous cell carcinoma (2022) (3)
- FAM135B sustains the reservoir of Tip60‐ATM assembly to promote DNA damage response (2022) (3)
- Aberrant expression of Notch1 in cervical cancer (2007) (2)
- Flotillin 1 promotes EMT of human small cell lung cancer via TGF-β signaling pathway (2018) (2)
- Epigenetic silencing BCL 6 B induced colorectal cancer proliferation and metastasis by inhibiting P 53 signaling (2015) (2)
- Regulation of OLC1 protein expression by the anaphase-promoting complex (2019) (2)
- Deregulated expression and subcellular localization of CPSF6, a circRNA-binding protein, promote malignant development of esophageal squamous cell carcinoma (2022) (2)
- Integrated multi-omics profiling yields a clinically relevant molecular classification for esophageal squamous cell carcinoma. (2022) (2)
- Tumor Suppressor p53 Can Participate in Transcriptional Induction of the GADD45 Promoter in the Absence of Direct DNA Binding (1998) (2)
- Integration of genomic science and personalized cancer (2010) (2)
- Genomic Analyses Reveal Mutational Signatures and Frequently Altered Genes in Esophageal Squamous Cell Carcinoma (2020) (2)
- Identification of RNA-splicing factor Lsm12 as a novel tumor-associated gene and a potent biomarker in Oral Squamous Cell Carcinoma (OSCC) (2022) (2)
- Development Status of Medical Talent Education in Colleges and Universities and Discussion on National Macro-Control Policy (2019) (2)
- A key player in biomedical sciences and clinical service in China, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC) (2007) (2)
- ZNF292 suppresses proliferation of ESCC cells through ZNF292/SKP2/P27 signaling axis (2021) (2)
- Feed‐forward activation of STAT3 signaling limits the efficacy of c‐Met inhibitors in esophageal squamous cell carcinoma (ESCC) treatment (2021) (2)
- Corrigendum: Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions (2014) (2)
- MTA 1 downregulation inhibits malignant potential in a small cell lung cancer cell line (1)
- A Potential Mechanism for Tumorigenesis Regulation of Insulin-like Growth Factor II P 3 Promoter by p 53 : Updated Version (2006) (1)
- Electric oscillation and coupling of chromatin regulate chromosome packaging and transcription in eukaryotic cells (2012) (1)
- Corrigendum to “A PLK1 kinase inhibitor enhances the chemosensitivity of cisplatin by inducing pyroptosis in oesophageal squamous cell carcinoma” [EBioMedicine 41 (2019) 244–255] (2019) (1)
- Conditional Mutation of Pkd2 Causes Cystogenesis and Upregulates (cid:1) -Catenin (2009) (1)
- [Effects of AS1411 on the apoptosis of taxol-resistant lung adenocarcinoma A549 cell]. (2014) (1)
- A PLK1 Kinase Inhibitor Enhances the Chemosensitivity of Cisplatin by Inducing Pyroptosis in Esophageal Squamous Cell Carcinoma (2019) (1)
- Corrigendum to “KDM4C, a H3K9me3 histone demethylase, is involved in the maintenance of human ESCC-initiating cells by epigenetically enhancing SOX2 expression” [Neoplasia 18 (2016) 594-609] (2016) (1)
- [Clinical significance of abnormal expression of Aurora-A in human esophageal squamous cell carcinoma with or without lymph node metastasis]. (2010) (1)
- Therapeutics , Targets , and Chemical Biology DNA Methylation-Mediated Repression of miR-886-3 p Predicts Poor Outcome of Human Small Cell Lung Cancer (2013) (1)
- Corrigendum to "A PLK1 kinase inhibitor enhances the chemosensitivity of cisplatin by inducing pyroptosis in oesophageal squamous cell carcinoma" [EBioMedicine 41 (2019) 244-255]. (2021) (1)
- [Suppression of HCT116 growth of cells by Gadd45]. (2003) (1)
- Analysis and validation of PI3K/AKT signaling pathway associated with overall survival time of patients with HER2-positive breast cancer (2018) (1)
- The p53-dependent -y-Ray Response of GADD451 (2011) (1)
- The Involvement of S 100 A 14 in Cell Invasion by Affecting Expression and Function of Matrix Metalloproteinase ( MMP )-2 via P 53-dependent Transcriptional Regulation (2012) (1)
- [Expression and clinical significance of BRCA1 in human esophageal squamous cell carcinoma]. (2012) (1)
- Migfilin protein promotes migration and invasion in human glioma through epidermal growth factor receptor-mediated phospholipase C-γ and STAT3 protein signaling pathways. (2013) (0)
- [Gadd45 mediated G2/M cell cycle arrest induced by BRCA1]. (2004) (0)
- Multi-region sequencing unveils novel actionable targets and spatial heterogeneity in esophageal squamous cell carcinoma (2019) (0)
- Editor's Note: Overexpression of Aurora-A Contributes to Malignant Development of Human Esophageal Squamous Cell Carcinoma (2020) (0)
- AD Award Number : DAMD 17-001-0414 TITLE : Gadd 45 Mediates the BRCAl-Induced Cell Cycle Arrest (0)
- Induction ofCellular p53Activity byDNA-Damaging AgentsandGrowthArrest (1993) (0)
- The chromosome 11q13.3 amplification associated lymph node metastasis is driven by miR-548k through modulating tumor microenvironment (2018) (0)
- Electric fields generated by synchronized oscillations of microtubules, centrosomes and chromosomes regulate the dynamics of mitosis and meiosis (2012) (0)
- Tumor-derived miR-20b-5p promotes lymphatic metastasis of esophageal squamous cell carcinoma by remodeling the tumor microenvironment (2023) (0)
- Transcriptional activation of Nlp by estrogen-ERα in breast cancer. (2017) (0)
- Study on mitotic spindle and midbody extraction (2014) (0)
- PTBP1 promotes IRES-mediated translation of cyclin B1in cancer (2022) (0)
- Design and Application of Clinical Big Data Management System for Oncology (2022) (0)
- Researchers Should Have Respect for the Originator of the Cell Lines (2005) (0)
- Functional interaction between Oct-1 and NF-YA proteins regulates the p53-independent induction of the GADD45 following DNA damage (2001) (0)
- MiR-423-5p in brain metastasis: potential role in diagnostics and molecular biology (2018) (0)
- Gadd45 Mediates the BRCA1-Induced Cell Cycle Arrest (2001) (0)
- Author Correction: Whole-genome sequencing of 508 patients identifies key molecular features associated with poor prognosis in esophageal squamous cell carcinoma (2022) (0)
- On Balancing Mechanism Between Supply of Medical Education and Demand for Clinicians in China (2019) (0)
- Mutant TP53 G245C and R273H promote cellular malignancy in esophageal squamous cell carcinoma (2018) (0)
- The long non-coding RNA colon cancer-associated transcript 1-Vimentin axis promoting the migration and invasion of HeLa cells. (2023) (0)
- Transcriptional Downregulation of miR-4306 serves as a New Therapeutic Target for Triple Negative Breast Cancer: Erratum (2023) (0)
- Author Correction: Whole-genome sequencing of 508 patients identifies key molecular features associated with poor prognosis in esophageal squamous cell carcinoma (2022) (0)
- Advances in Brief Activation of the Transcription Factor Oct-1 in Response to DNA Damage (2000) (0)
- Erratum to: Crystal structure of human Gadd45γ reveals an active dimer (2012) (0)
- Identification of RNA-splicing factor Lsm12 as a novel tumor-associated gene and a potent biomarker in Oral Squamous Cell Carcinoma (OSCC) (2022) (0)
- CDK12 inhibition enhances sensitivity of HER2+ breast cancers to HER2-TKI via suppressing PI3K/AKT (2020) (0)
- The metabolic genomic atlas reveals potential drivers and clinically relevant insights into the etiology of esophageal squamous cell carcinoma (2022) (0)
- Advancing science and education through a novel collaboration platform between the University of Michigan and Peking University Health Science Center (2021) (0)
- PAFR/Stat3 axis maintains the symbiotic ecosystem between tumor and stroma to facilitate tumor malignancy (2022) (0)
- Abstract 1064: RASSF10 suppresses colorectal cancer growth by activating p53 signaling and sensitizes colorectal cancer cell to docetaxel (2015) (0)
- Author correction: Quiescence and attenuated DNA damage response promote survival of esophageal cancer stem cells (2020) (0)
- Erratum to: Crystal structure of human Gadd45γ reveals an active dimer (2012) (0)
- Whole-genome sequencing of 508 patients identifies key molecular features associated with poor prognosis in esophageal squamous cell carcinoma (2020) (0)
- Accurate detection of CNV based on single-nucleotide variants recalibration and image classification from whole genome sequencing (2020) (0)
- HEMATOPOIESIS AND STEM CELLS Gadd 45 a regulates hematopoietic stem cell stress responses in mice (2014) (0)
- Abstract 3993: MiRNA-141 and methylation regulation of WNT signal pathway by suppressingSOX17 in esophageal cancer (2012) (0)
- A liquid biopsy signature predicts lymph node metastases in T1 oesophageal squamous cell carcinoma: implications for precision treatment strategy (2022) (0)
- Corrigendum to 'ad-PUMA sensitizes drug-resistant choriocarcinoma cells to chemotherapeutic agents' [gynecologic oncology 107 (2007) 505-512]. (2020) (0)
- Demands and challenges to the personal medicine of cancer research (2012) (0)
- Abstract 4822: The 3'UTR ofCAPZA1functions separately and oppositely to its host gene in ESCC (2020) (0)
- Cells to Cisplatin and Pentoxifylline Disruption of p 53 Function Sensitizes Breast Cancer MCF-7 Updated (2006) (0)
- Advances in Brief Disruption of p 53 Function Sensitizes Breast Cancer MCF-7 Cells to Cisplatin and Pentoxifylline (2006) (0)
- Joining forces to drive biomedical translation (2015) (0)
- miRNAs Associated With Brain Metastatic Lung Adenocarcinoma (2017) (0)
- Cancer Therapy : Preclinical Role of Smac in Determining the Chemotherapeutic Response of Esophageal Squamous Cell Carcinoma (2011) (0)
- Src heterodimerically activates Lyn or Fyn to serve as targets for the diagnosis and treatment of esophageal squamous cell carcinoma. (2023) (0)
- Whole Genome Sequencing of 508 Patients Identified Key Molecular Features Associated with Poor Prognosis in Esophageal Squamous Cell Carcinoma (2019) (0)
- Long noncoding RNA PCAT1, a novel serum-based biomarker, enhances cell growth by sponging miR-326 in oesophageal squamous cell carcinoma (2019) (0)
- Extracellular vesicles derived from oesophageal cancer containing PHB promote muscle wasting via regulating PHGDH/Bcl-/caspase- pathway (2021) (0)
- WS5-01 Gadd45a inhibits Aurora-A kinase activity and regulates centrosome stability(Histochemistry of Protein Function) (2007) (0)
- Activation of Aurora A kinase increases YAP stability via blockage of autophagy (2019) (0)
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