Richard A. Roth
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Richard A. Rothbiology Degrees
Biology
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Cell Biology
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Neuroscience
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Biochemistry
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Biology
Richard A. Roth's Degrees
- PhD Biochemistry Stanford University
- Bachelors Chemistry University of California, Berkeley
Why Is Richard A. Roth Influential?
(Suggest an Edit or Addition)Richard A. Roth's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Expression of a Constitutively Active Akt Ser/Thr Kinase in 3T3-L1 Adipocytes Stimulates Glucose Uptake and Glucose Transporter 4 Translocation* (1996) (1316)
- The human insulin receptor cDNA: The structural basis for hormone-activated transmembrane signalling (1985) (1224)
- Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose (1986) (862)
- Insulin-like growth factor II receptor as a multifunctional binding protein (1987) (788)
- Sequence of protein disulphide isomerase and implications of its relationship to thioredoxin (1985) (544)
- PRAS40 Regulates mTORC1 Kinase Activity by Functioning as a Direct Inhibitor of Substrate Binding* (2007) (494)
- Akt, a Pleckstrin Homology Domain Containing Kinase, Is Activated Primarily by Phosphorylation* (1996) (494)
- Evidence of insulin-stimulated phosphorylation and activation of the mammalian target of rapamycin mediated by a protein kinase B signaling pathway. (1998) (493)
- Up-regulation of Akt3 in Estrogen Receptor-deficient Breast Cancers and Androgen-independent Prostate Cancer Lines* (1999) (484)
- Inhibition of mTOR Activity Restores Tamoxifen Response in Breast Cancer Cells with Aberrant Akt Activity (2004) (380)
- Identification of a Proline-rich Akt Substrate as a 14-3-3 Binding Partner* (2003) (372)
- Insulin stimulates the kinase activity of RAC‐PK, a pleckstrin homology domain containing ser/thr kinase. (1995) (366)
- Stimulation of Lipolysis and Hormone-sensitive Lipase via the Extracellular Signal-regulated Kinase Pathway* (2001) (358)
- Construction and Characterization of a Conditionally Active Version of the Serine/Threonine Kinase Akt* (1998) (341)
- Insulin-Stimulated Akt Kinase Activity Is Reduced in Skeletal Muscle From NIDDM Subjects (1998) (334)
- Reduced hippocampal insulin-degrading enzyme in late-onset Alzheimer's disease is associated with the apolipoprotein E-epsilon4 allele. (2003) (328)
- Regulation of GLUT1 Gene Transcription by the Serine/Threonine Kinase Akt1* (1999) (317)
- Insulin receptor: evidence that it is a protein kinase. (1983) (310)
- Modulation of Insulin Receptor Substrate-1 Tyrosine Phosphorylation and Function by Mitogen-activated Protein Kinase* (1997) (301)
- Replacement of lysine residue 1030 in the putative ATP-binding region of the insulin receptor abolishes insulin- and antibody-stimulated glucose uptake and receptor kinase activity. (1987) (300)
- Juxtamembrane tyrosine residues couple the Eph family receptor EphB2/Nuk to specific SH2 domain proteins in neuronal cells (1997) (285)
- Expression and characterization of a functional human insulin-like growth factor I receptor. (1988) (281)
- Divergent effects of exercise on metabolic and mitogenic signaling pathways in human skeletal muscle (1998) (271)
- Protein kinase C directly phosphorylates the insulin receptor in vitro and reduces its protein-tyrosine kinase activity. (1986) (247)
- Protein kinase C modulation of insulin receptor substrate-1 tyrosine phosphorylation requires serine 612. (1997) (246)
- Modulation of Insulin Receptor Substrate-1 Tyrosine Phosphorylation by an Akt/Phosphatidylinositol 3-Kinase Pathway* (1999) (217)
- The Role of Glycogen Synthase Kinase 3β in Insulin-stimulated Glucose Metabolism* (1999) (208)
- Ras p21 as a potential mediator of insulin action in Xenopus oocytes. (1987) (202)
- Identification of mannose 6-phosphate in two asparagine-linked sugar chains of recombinant transforming growth factor-beta 1 precursor. (1988) (201)
- Identification of a human Akt3 (protein kinase B gamma) which contains the regulatory serine phosphorylation site. (1999) (200)
- Modulation of Insulin-stimulated Degradation of Human Insulin Receptor Substrate-1 by Serine 312 Phosphorylation* (2003) (200)
- Structure of the receptor for insulin-like growth factor II: the puzzle amplified. (1988) (189)
- Mechanism of Akt1 inhibition of breast cancer cell invasion reveals a protumorigenic role for TSC2. (2006) (189)
- Phosphatidylinositol kinase or an associated protein is a substrate for the insulin receptor tyrosine kinase. (1990) (185)
- Inorganic polyphosphate stimulates mammalian TOR, a kinase involved in the proliferation of mammary cancer cells (2003) (176)
- Grb-IR: a SH2-domain-containing protein that binds to the insulin receptor and inhibits its function. (1995) (159)
- The B cell antigen receptor activates the Akt (protein kinase B)/glycogen synthase kinase-3 signaling pathway via phosphatidylinositol 3-kinase. (1999) (159)
- Overexpression of protein kinase C isoenzymes alpha, beta I, gamma, and epsilon in cells overexpressing the insulin receptor. Effects on receptor phosphorylation and signaling. (1993) (156)
- Acute insulin action requires insulin receptor kinase activity: introduction of an inhibitory monoclonal antibody into mammalian cells blocks the rapid effects of insulin. (1987) (154)
- Ligand-dependent Interaction of Estrogen Receptor-α with Members of the Forkhead Transcription Factor Family* (2001) (152)
- Improved Glucose Tolerance Restores Insulin-Stimulated Akt Kinase Activity and Glucose Transport in Skeletal Muscle From Diabetic Goto-Kakizaki Rats (1997) (140)
- An unusual active site identified in a family of zinc metalloendopeptidases. (1992) (138)
- Interactions of recombinant and platelet transforming growth factor-beta 1 precursor with the insulin-like growth factor II/mannose 6-phosphate receptor. (1989) (135)
- Activation of Protein Kinase B/Akt Is Sufficient to Repress the Glucocorticoid and cAMP Induction of Phosphoenolpyruvate Carboxykinase Gene* (1998) (126)
- The receptor for insulin‐like growth factor II mediates an insulin‐like response. (1987) (124)
- A panel of monoclonal antibodies for the type I insulin-like growth factor receptor. Epitope mapping, effects on ligand binding, and biological activity. (1992) (118)
- Insulin activates the kinase activity of the Raf-1 proto-oncogene by increasing its serine phosphorylation. (1990) (117)
- Human insulin-degrading enzyme shares structural and functional homologies with E. coli protease III. (1988) (116)
- Accurate and efficient cleavage of the human insulin proreceptor by the human proprotein-processing protease furin. Characterization and kinetic parameters using the purified, secreted soluble protease expressed by a recombinant baculovirus. (1994) (116)
- Protein kinase B/Akt phosphorylation of PDE3A and its role in mammalian oocyte maturation (2006) (113)
- Expression of a functional human insulin receptor from a cloned cDNA in Chinese hamster ovary cells. (1985) (111)
- In vivo cross-linking of protein disulfide isomerase to immunoglobulins. (1987) (105)
- Differential regulation of endogenous glucose-6-phosphatase and phosphoenolpyruvate carboxykinase gene expression by the forkhead transcription factor FKHR in H4IIE-hepatoma cells. (2001) (105)
- Bacitracin: an inhibitor of the insulin degrading activity of glutathione-insulin transhydrogenase. (1981) (101)
- Insulin action is blocked by a monoclonal antibody that inhibits the insulin receptor kinase. (1986) (101)
- Characterization and Cloning of a 58/53-kDa Substrate of the Insulin Receptor Tyrosine Kinase (*) (1996) (99)
- C5a-dependent up-regulation in vivo of lung vascular P-selectin. (1997) (98)
- Monoclonal antibodies to the human insulin receptor block insulin binding and inhibit insulin action. (1982) (93)
- Inhibition of insulin degradation by hepatoma cells after microinjection of monoclonal antibodies to a specific cytosolic protease. (1986) (92)
- The insulin receptor-related receptor. Tissue expression, ligand binding specificity, and signaling capabilities. (1992) (90)
- Modulation of human insulin receptor substrate-1 tyrosine phosphorylation by protein kinase Cdelta. (2004) (90)
- The regulatory role of known tyrosine autophosphorylation sites of the insulin receptor kinase domain. An assessment by replacement with neutral and negatively charged amino acids. (1991) (87)
- Expression of constitutively active Akt-3 in MCF-7 breast cancer cells reverses the estrogen and tamoxifen responsivity of these cells in vivo. (2003) (85)
- Protein Kinase B/akt and Rab5 Mediate Ras Activation of Endocytosis* (1998) (85)
- Phosphorylation of Purified Insulin Receptor by cAMP Kinase (1987) (85)
- Akt Modulates STAT3-mediated Gene Expression through a FKHR (FOXO1a)-dependent Mechanism* (2003) (83)
- Oncogenic transformation of cells by a conditionally active form of the protein kinase Akt/PKB. (2000) (83)
- Muscle fiber type-specific defects in insulin signal transduction to glucose transport in diabetic GK rats. (1999) (83)
- Activation of protein kinase C alpha inhibits insulin-stimulated tyrosine phosphorylation of insulin receptor substrate-1. (1994) (83)
- Interactions of the receptor for insulin-like growth factor II with mannose-6-phosphate and antibodies to the mannose-6-phosphate receptor. (1987) (82)
- Overexpression of insulin degrading enzyme: cellular localization and effects on insulin signaling. (1997) (80)
- Defective internalization of insulin and its receptor in cells expressing mutated insulin receptors lacking kinase activity. (1987) (80)
- A region of the insulin receptor important for ligand binding (residues 450-601) is recognized by patients' autoimmune antibodies and inhibitory monoclonal antibodies. (1991) (78)
- Heregulin regulation of Akt/protein kinase B in breast cancer cells. (1999) (78)
- Akt promotes increased mammalian cell size by stimulating protein synthesis and inhibiting protein degradation. (2003) (78)
- Role of disulfide interchange enzyme in immunoglobulin synthesis. (1981) (77)
- Purification and Characterization of Insulin-Degrading Enzyme From Human Erythrocytes (1986) (76)
- Activation of Protein Kinase Cα Inhibits Signaling by Members of the Insulin Receptor Family (*) (1995) (73)
- Insulin and insulinlike growth factor receptors and responses in cultured human muscle cells. (1986) (72)
- Characterization of a 60-kilodalton substrate of the insulin receptor kinase. (1994) (72)
- Binding properties of chimeric insulin receptors containing the cysteine-rich domain of either the insulin-like growth factor I receptor or the insulin receptor related receptor. (1991) (71)
- A membrane-anchored cytoplasmic domain of the human insulin receptor mediates a constitutively elevated insulin-independent uptake of 2-deoxyglucose. (1987) (70)
- Purification and characterization of the human brain insulin receptor. (1986) (68)
- Degradation of Insulin by Isolated Mouse Pancreatic Acini: Evidence for Cell Surface Protease Activity (1984) (65)
- Dual regulation of glycogen metabolism by insulin and insulin-like growth factors in human hepatoma cells (HEP-G2). Analysis with an anti-receptor monoclonal antibody. (1984) (64)
- Regulation of FRTL-5 thyroid cell growth by phosphatidylinositol (OH) 3 kinase-dependent Akt-mediated signaling. (2001) (63)
- Protein Kinase B/Akt Induces Resumption of Meiosis inXenopus Oocytes* (1998) (63)
- Purification and characterization of the receptor for insulin-like growth factor I. (1986) (60)
- Mapping surface structures of the human insulin receptor with monoclonal antibodies: localization of main immunogenic regions to the receptor kinase domain. (1986) (60)
- Insulin-degrading enzyme: stable expression of the human complementary DNA, characterization of its protein product, and chromosomal mapping of the human and mouse genes. (1990) (59)
- Identification of insulin-degrading enzyme on the surface of cultured human lymphocytes, rat hepatoma cells, and primary cultures of rat hepatocytes. (1982) (58)
- Regulation of the forkhead transcription factor FKHR (FOXO1a) by glucose starvation and AICAR, an activator of AMP-activated protein kinase. (2002) (58)
- Protein kinase C modulates the insulin-stimulated increase in Akt1 and Akt3 activity in 3T3-L1 adipocytes. (1998) (54)
- Insulin receptor structure and function in normal and pathological conditions. (1990) (53)
- Expression and characterization of a functional human insulin like growth factor-I receptor. J Biol Chem 263:11486-11492 (1988) (53)
- Identification of SHC as a substrate of the insulin receptor kinase distinct from the GAP-associated 62 kDa tyrosine phosphoprotein. (1993) (53)
- The MMAC1 tumor suppressor phosphatase inhibits phospholipase C and integrin-linked kinase activity (2000) (52)
- Insulysin and pitrilysin: insulin-degrading enzymes of mammals and bacteria. (1995) (52)
- Insulin and insulin-like growth factor receptors and responses. (1988) (49)
- In vivo association of [125I]-insulin with a cytosolic insulin-degrading enzyme: detection by covalent cross-linking and immunoprecipitation with a monoclonal antibody. (1987) (49)
- Identification of a lymphocyte enzyme that catalyzes pentamer immunoglobulin M assembly. (1981) (48)
- Characterization of the Serum from a Patient with Insulin Resistance and Hypoglycemia: Evidence for Multiple Populations of Insulin Receptor Antibodies with Different Receptor Binding and Insulin-mimicking Activities (1984) (48)
- Protein kinase B/Akt is essential for the insulin- but not progesterone-stimulated resumption of meiosis in Xenopus oocytes. (2003) (46)
- Comparison of the enzymatic and biochemical properties of human insulin-degrading enzyme and Escherichia coli protease III. (1992) (46)
- PKCδ-mediated IRS-1 Ser24 phosphorylation negatively regulates IRS-1 function (2006) (46)
- Characterization of the insulin and insulin-like growth factor receptors and responsitivity of a fibroblast/adipocyte cell line before and after differentiation. (1986) (44)
- Comparison of the signaling abilities of the Drosophila and human insulin receptors in mammalian cells. (1995) (44)
- Regulation of insulin receptor kinase activity by insulin mimickers and an insulin antagonist. (1983) (44)
- Insulin receptor-related receptor messenger ribonucleic acid is focally expressed in sympathetic and sensory neurons and renal distal tubule cells. (1993) (44)
- Activation of protein kinase B/cAkt in hepatocytes is sufficient for the induction of expression of the gene encoding glucokinase. (2000) (43)
- Degradation of insulin-like growth factors I and II by a human insulin degrading enzyme. (1984) (42)
- Activation of transforming potential of the human insulin receptor gene. (1987) (42)
- Cellular distribution of insulin-degrading enzyme gene expression. Comparison with insulin and insulin-like growth factor receptors. (1994) (41)
- Gene expression profiling in prostate cancer cells with Akt activation reveals Fra-1 as an Akt-inducible gene. (2003) (40)
- Characterization of insulin-stimulated protein serine/threonine kinases in CHO cells expressing human insulin receptors with point and deletion mutations. (1992) (39)
- Preferential degradation of the beta subunit of purified insulin receptor. Effect on insulin binding and protein kinase activities of the receptor. (1983) (38)
- Identification of glutamate-169 as the third zinc-binding residue in proteinase III, a member of the family of insulin-degrading enzymes. (1993) (37)
- Interactions of a monoclonal antibody to the insulin receptor with receptors for insulin-like growth factors. (1983) (36)
- Human red blood cell insulin-degrading enzyme and rat skeletal muscle insulin protease share antigenic sites and generate identical products from insulin. (1990) (35)
- Covalent linkage of 125I-insulin to a cytosolic insulin-degrading enzyme. (1985) (35)
- Insulin-stimulated tyrosine phosphorylation of protein kinase C alpha: evidence for direct interaction of the insulin receptor and protein kinase C in cells. (1994) (35)
- Identification of serines‐1035/1037 in the kinase domain of the insulin receptor as protein kinase Cα mediated phosphorylation sites (1994) (35)
- Insulin-mimetic anti-insulin receptor monoclonal antibodies stimulate receptor kinase activity in intact cells. (1990) (33)
- Heterologous transmembrane signaling by a human insulin receptor-v-ros hybrid in Chinese hamster ovary cells. (1987) (32)
- Monoclonal antibody alpha IR-3 inhibits the ability of insulin-like growth factor II to stimulate a signal from the type I receptor without inhibiting its binding. (1990) (32)
- Substrates and signalling complexes: The tortured path to insulin action (1992) (32)
- Regulation of the Forkhead Transcription Factor FKHR (FOXO1a) by Glucose Starvation and AICAR, an Activator of AMP-Activated Protein Kinase. (2002) (31)
- Regulation of the insulin receptor by a monoclonal anti-receptor antibody. Evidence that receptor down regulation can be independent of insulin action. (1983) (30)
- On the Mechanism for Neomycin Reversal of Wortmannin Inhibition of Insulin Stimulation of Glucose Uptake* (2004) (29)
- The Insulin Receptor Substrate (IRS)-1 Pleckstrin Homology Domain Functions in Downstream Signaling* (2001) (29)
- Identification of a monoclonal antibody which can distinguish between two distinct species of the type I receptor for insulin-like growth factor. (1986) (29)
- Biochemical mechanisms of insulin resistance. (1994) (28)
- Insulin-stimulated serine and threonine phosphorylation of the human insulin receptor. An assessment of the role of serines 1305/1306 and threonine 1348 by their replacement with neutral or negatively charged amino acids. (1991) (27)
- Characterization of the Endogenous Insulin Receptor-related Receptor in Neuroblastomas (*) (1995) (27)
- Increased workload fully activates the blunted IRS-1/PI3-kinase/Akt signaling pathway in atrophied uremic muscle. (2008) (26)
- Leucine-stimulated mTOR signaling is partly attenuated in skeletal muscle of chronically uremic rats. (2011) (26)
- Identification of residues in the insulin molecule important for binding to insulin-degrading enzyme. (1990) (25)
- Analysis of intracellular protein function by antibody injection. (1988) (25)
- Evidence for hybrid rodent and human insulin receptors in transfected cells. (1991) (24)
- PKCdelta-mediated IRS-1 Ser24 phosphorylation negatively regulates IRS-1 function. (2006) (24)
- A Constitutively Active Version of the Ser/Thr Kinase Akt Induces Production of the obGene Product, Leptin, in 3T3-L1 Adipocytes. (1997) (24)
- Characterization of an insulin degrading enzyme from cultured human lymphocytes. (1985) (24)
- Insulin-ricin B chain conjugate. A hybrid molecule with ricin-binding activity and insulin biological activity. (1981) (24)
- Activation of protein kinase C alpha inhibits signaling by members of the insulin receptor family. (1995) (24)
- Assessment of the in situ tyrosine kinase activity of mutant insulin receptors lacking tyrosine autophosphorylation sites 1162 and 1163. (1991) (23)
- Insulin is degraded extracellularly in wounds by insulin-degrading enzyme (EC 3.4.24.56). (1997) (22)
- Identification of serines-967/968 in the juxtamembrane region of the insulin receptor as insulin-stimulated phosphorylation sites. (1994) (22)
- Identification of AKT-regulated genes in inducible MERAkt cells. (2001) (22)
- Evidence for two distinct 60-kilodalton substrates of the SRC tyrosine kinase. (1994) (21)
- Molecular basis of the activation of the tumorigenic potential of Gag-insulin receptor chimeras. (1991) (20)
- The insulin receptor family. (1993) (19)
- Correlation between insulin receptor occupancy and tyrosine kinase activity at low insulin concentrations and effect of major histocompatibility complex class I-derived peptide. (1993) (19)
- Mechanisms of receptor-mediated transmembrane communication. (1986) (18)
- Linking functional domains of the human insulin receptor with the bacterial aspartate receptor. (1986) (18)
- Binding of SH2 containing proteins to the insulin receptor: A new way for modulating insulin signalling (1998) (18)
- A nonradioactive assay for the insulin receptor tyrosine kinase: use in monitoring receptor kinase activity after activation of overexpressed protein kinase C alpha and high glucose treatment. (1995) (17)
- Characterization of latent recombinant TGF‐β2 produced by chinese hamster ovary cells (1991) (17)
- Comparison of the signaling abilities of the cytoplasmic domains of the insulin receptor and the insulin receptor-related receptor in 3T3-L1 adipocytes. (1998) (17)
- Inhibition of insulin receptor phosphorylation by peptides derived from major histocompatibility complex class I antigens. (1989) (17)
- A role for the insulin-like growth factor II/mannose-6-phosphate receptor in the insulin-induced inhibition of protein catabolism. (1989) (16)
- Mechanism of Akt 1 inhibition of breast cancer cell invasion reveals a protumorigenic role for TSC 2 (2006) (16)
- Characterization of latent transforming growth factor-beta 2 from monkey kidney cells. (1991) (15)
- A constitutively active version of the Ser/Thr kinase Akt induces production of the ob gene product, leptin, in 3T3-L1 adipocytes. (1997) (15)
- Intracellular Events in the Differentiation of B Lymphocytes to Pentamer IgM Synthesis (1979) (15)
- Effects of covalently linked insulin dimers on receptor kinase activity and receptor down regulation (1984) (14)
- Plate binding assay for monoclonal anti-receptor antibodies. (1985) (14)
- Insulin-like growth factor receptors: recent developments and new methodologies. (1994) (13)
- Activation of protein kinase C stimulates the tyrosine phosphorylation and guanosine triphosphatase-activating protein association of p60 in rat hepatoma cells. (1995) (13)
- ATP and other nucleoside triphosphates inhibit the binding of insulin to its receptor. (1984) (13)
- Monoclonal antibodies to the insulin receptor. (1985) (10)
- Effect of experimental diabetes on insulin binding by renal basolateral membranes. (1986) (10)
- Inactivation of normal beta-D-galactosidase by antibodies to defective forms of the enzyme. (1975) (9)
- Insulin-ricin B chain conjugate has enhanced biological activity in insulin-insensitive cells. (1983) (9)
- Disruption of a putative SH3 domain and the proline‐rich motifs in the 53‐kDa substrate of the insulin receptor kinase does not alter its subcellular localization or ability to serve as a substrate (1998) (9)
- Endogenous substrates of the insulin receptor: studies with cells expressing wild-type and mutant receptors. (1991) (9)
- Insulin‐cholera toxin binding unit conjugate: A hybrid molecule with insulin biological activity and cholera toxin binding specificity (1983) (9)
- Insulin degradation by Madin-Darby canine kidney cells expressing the insulin receptor. (1997) (8)
- Insulin Receptor Structure (1990) (8)
- Insulin Receptor Signaling in Madin-Darby Canine Kidney Cells Overexpressing the Human Insulin Receptor (1994) (8)
- Production and characterization of a monoclonal antibody to rat liver thiol: protein-disulfide oxidoreductase/glutathione-insulin transhydrogenase. (1984) (7)
- Production of antibodies that inhibit the binding of insulin to its receptor. (1981) (7)
- Antibody-induced down-regulation of a mutated insulin receptor lacking an intact cytoplasmic domain. (1987) (7)
- Role of the juxtamembrane tyrosine in insulin receptor-mediated tyrosine phosphorylation of p60 endogenous substrates. (1996) (6)
- Development of an assay for bioactive insulin. (1998) (6)
- Various proteins modulate the kinase activity of the insulin receptor (1990) (5)
- Monoclonal antibodies to the insulin receptor as probes of insulin receptor structure and function. (1986) (5)
- Concentration-dependent stimulatory and inhibitory effect of troglitazone on insulin-induced fatty acid synthase expression and protein kinase B activity in 3T3-L1 adipocytes (2002) (5)
- Dissociation of the tetrameric form of beta-D-galactosidase by inactivating antibodies. (1975) (5)
- A solid-phase competitive radioimmunoassay for the insulin receptor. (1986) (4)
- Insulin is degraded extracellularly in wounds by insulin-degrading enzyme (EC 3.4.24.56 ). (1997) (4)
- Internalization and degradation of insulin by a human insulin receptor-v-ros hybrid in Chinese hamster ovary cells. (1989) (3)
- Characterization of a protein which binds phosphatidylinositol 3,4,5-trisphosphate and 4,5-bisphosphate. (1994) (2)
- The human insulin receptor cDNA: a new tool to study the function of this receptor. (1987) (2)
- Insulin degrading enzyme expression is reduced in hippocampus of Alzheimer's disease patients (2000) (1)
- Binding and inhibit insulin action. (1982) (1)
- Grb-IR : A SH 2-domain-containing protein that binds to the insulin receptor and inhibits its function ( phosphatidylinositol 3-kinase / yeast two-hybrid system / insulin-receptor substrate 1 ) (2005) (1)
- Induction of Glut1 and PGK1 gene expression in response to insulin or hypoxia (1999) (0)
- A novel zinc binding domain conserved in metalloendopeptidases from bacteria to man (1992) (0)
- Substrates of the insulin receptor kinase. (1990) (0)
- Modulation of STAT3 Gene Transcription through the PI 3-Kinase/Akt Pathway: Interaction between the Transcription Factors FKHR and STAT3 (2001) (0)
- Outfoxing liver Cancer With plSARF Tumor (2004) (0)
- Modulation of the substrate specificity of the insulin receptor tyrosine kinase (1988) (0)
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What Schools Are Affiliated With Richard A. Roth?
Richard A. Roth is affiliated with the following schools:
