Robert E. Hammer

Q: What Schools Are Affiliated With Robert E. Hammer

Robert E. Hammer is affiliated with the following schools: University of Manchester Institute of Science and Technology, Vrije Universiteit Amsterdam, University of Chicago, Baylor College of Medicine, University of Washington, University of Bonn, University of Münster, University of Texas Southwestern Medical Center, University of Pennsylvania

Robert E. Hammer's AcademicInfluence.com Rankings

Robert E. Hammer

Biology

#5843

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#8420

Historical Rank

Molecular Biology

#565

World Rank

#578

Historical Rank

biology Degrees

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Biology

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Robert E. Hammer's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Narcolepsy in orexin Knockout Mice Molecular Genetics of Sleep Regulation (1999) (2897)
Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery. (1993) (1555)
Synaptotagmin I: A major Ca2+ sensor for transmitter release at a central synapse (1994) (1450)
Cholesterol and Bile Acid Metabolism Are Impaired in Mice Lacking the Nuclear Oxysterol Receptor LXRα (1998) (1428)
Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21. (2007) (1378)
Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41 (2008) (1368)
Dramatic growth of mice that develop from eggs microinjected with metallothionein–growth hormone fusion genes (1982) (1303)
Synaptic assembly of the brain in the absence of neurotransmitter secretion. (2000) (1299)
Reeler/Disabled-like Disruption of Neuronal Migration in Knockout Mice Lacking the VLDL Receptor and ApoE Receptor 2 (1999) (1253)
Tie2-Cre transgenic mice: a new model for endothelial cell-lineage analysis in vivo. (2001) (1195)
The germfree state prevents development of gut and joint inflammatory disease in HLA-B27 transgenic rats (1994) (1136)
Production of transgenic rabbits, sheep and pigs by microinjection (1985) (1041)
White Fat Progenitor Cells Reside in the Adipose Vasculature (2008) (1029)
Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy (1999) (1018)
Spontaneous inflammatory disease in transgenic rats expressing HLA-B27 and human β 2m: An animal model of HLA-B27-associated human disorders (1990) (1011)
Targeted and natural (piebald-lethal) mutations of endothelin-B receptor gene produce megacolon associated with spotted coat color in mice (1994) (987)
Interaction of endothelin-3 with endothelin-B receptor is essential for development of epidermal melanocytes and enteric neurons (1994) (935)
A Neuroligin-3 Mutation Implicated in Autism Increases Inhibitory Synaptic Transmission in Mice (2007) (907)
Normal luminal bacteria, especially Bacteroides species, mediate chronic colitis, gastritis, and arthritis in HLA-B27/human beta2 microglobulin transgenic rats. (1996) (840)
Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a. (1996) (830)
Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice. (2000) (818)
Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy. (1998) (809)
Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells. (1997) (800)
Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion (2002) (746)
Essential functions of synapsins I and II in synaptic vesicle regulation (1995) (712)
Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2. (1998) (695)
Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9. (2005) (690)
Metallothionein-human GH fusion genes stimulate growth of mice. (1983) (669)
The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development. (1998) (666)
Cranial and cardiac neural crest defects in endothelin-A receptor-deficient mice. (1998) (650)
Diminished Hepatic Response to Fasting/Refeeding and Liver X Receptor Agonists in Mice with Selective Deficiency of Sterol Regulatory Element-binding Protein-1c* (2002) (634)
Secreted PCSK9 decreases the number of LDL receptors in hepatocytes and in livers of parabiotic mice. (2006) (626)
Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol. (2002) (622)
Distinct Narcolepsy Syndromes in Orexin Receptor-2 and Orexin Null Mice Molecular Genetic Dissection of Non-REM and REM Sleep Regulatory Processes (2003) (609)
LDL receptor-related protein internalizes and degrades uPA-PAI-1 complexes and is essential for embryo implantation (1992) (585)
α-Neurexins couple Ca2+ channels to synaptic vesicle exocytosis (2003) (562)
Defective forebrain development in mice lacking gp330/megalin. (1996) (498)
Dual genetic pathways of endothelin-mediated intercellular signaling revealed by targeted disruption of endothelin converting enzyme-1 gene. (1998) (491)
The role of Rab3A in neurotransmitter release (1994) (468)
Acetate Dependence of Tumors (2014) (464)
Inducible inactivation of hepatic LRP gene by cre-mediated recombination confirms role of LRP in clearance of chylomicron remnants. (1998) (463)
Growth enhancement of transgenic mice expressing human insulin-like growth factor I. (1988) (463)
Modulation of Synaptic Plasticity and Memory by Reelin Involves Differential Splicing of the Lipoprotein Receptor Apoer2 (2005) (453)
Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene. (1997) (451)
Genetic engineering of livestock. (1989) (409)
Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions. (2004) (389)
Rat spermatogenesis in mouse testis (1996) (371)
Hyperactivated sperm motility driven by CatSper2 is required for fertilization (2003) (348)
SREBP cleavage-activating protein (SCAP) is required for increased lipid synthesis in liver induced by cholesterol deprivation and insulin elevation. (2001) (323)
Dependence of Mouse Embryonic Stem Cells on Threonine Catabolism (2009) (320)
Short-term synaptic plasticity is altered in mice lacking synapsin I (1993) (319)
Essential Roles in Synaptic Plasticity for Synaptogyrin I and Synaptophysin I (1999) (311)
Smooth muscle-selective deletion of guanylyl cyclase-A prevents the acute but not chronic effects of ANP on blood pressure (2002) (309)
Disruption of PPT1 or PPT2 causes neuronal ceroid lipofuscinosis in knockout mice (2001) (296)
Hepatic fibrosis, glomerulosclerosis, and a lipodystrophy-like syndrome in PEPCK-TGF-beta1 transgenic mice. (1997) (286)
Conformational Switch of Syntaxin-1 Controls Synaptic Vesicle Fusion (2008) (282)
Atherogenesis in transgenic mice expressing human apolipoprotein(a) (1992) (280)
Critical roles of the guanylyl cyclase B receptor in endochondral ossification and development of female reproductive organs. (2004) (280)
RAP, a specialized chaperone, prevents ligand‐induced ER retention and degradation of LDL receptor‐related endocytic receptors. (1996) (268)
Functional expression of low density lipoprotein receptor-related protein is controlled by receptor-associated protein in vivo. (1995) (266)
Expression of human growth hormone-releasing factor in transgenic mice results in increased somatic growth (1985) (265)
A Phospho-Switch Controls the Dynamic Association of Synapsins with Synaptic Vesicles (1999) (258)
Synaptophysin, a major synaptic vesicle protein, is not essential for neurotransmitter release. (1996) (255)
Production of transgenic rats by lentiviral transduction of male germ-line stem cells (2002) (245)
Susceptibility to inflammatory disease in HLA-B27 transgenic rat lines correlates with the level of B27 expression. (1993) (244)
Overexpression of Insig-1 in the livers of transgenic mice inhibits SREBP processing and reduces insulin-stimulated lipogenesis. (2004) (243)
Histopathology associated with elevated levels of growth hormone and insulin-like growth factor I in transgenic mice. (1989) (239)
Diversity of alpha-fetoprotein gene expression in mice is generated by a combination of separate enhancer elements. (1987) (239)
Transgenic mice expressing high plasma concentrations of human apolipoprotein B100 and lipoprotein(a). (1993) (238)
Experimental control of pancreatic development and maintenance (2002) (237)
Inflammatory disease in HLA‐B27 transgenic rats (1999) (236)
Deranged Calcium Signaling and Neurodegeneration in Spinocerebellar Ataxia Type 3 (2008) (234)
The Master Negative Regulator REST/NRSF Controls Adult Neurogenesis by Restraining the Neurogenic Program in Quiescent Stem Cells (2011) (233)
Decreased lipid synthesis in livers of mice with disrupted Site-1 protease gene (2001) (233)
Pancreatic neoplasia induced by SV40 T-antigen expression in acinar cells of transgenic mice. (1987) (228)
Insulin stimulation of SREBP-1c processing in transgenic rat hepatocytes requires p70 S6-kinase (2012) (224)
Dramatic pituitary hyperplasia in transgenic mice expressing a human growth hormone-releasing factor gene. (1988) (217)
Self renewal, expansion, and transfection of rat spermatogonial stem cells in culture. (2005) (216)
Overexpression of Sterol Regulatory Element-binding Protein-1a in Mouse Adipose Tissue Produces Adipocyte Hypertrophy, Increased Fatty Acid Secretion, and Fatty Liver* (2003) (215)
Vasculature White Fat Progenitor Cells Reside in the Adipose (2008) (213)
Unsupervised Natural Experience Rapidly Alters Invariant Object Representation in Visual Cortex (2008) (212)
Mutation of beta-glucosidase 2 causes glycolipid storage disease and impaired male fertility. (2006) (210)
Molecular mechanisms of hepatic steatosis and insulin resistance in the AGPAT2-deficient mouse model of congenital generalized lipodystrophy. (2009) (207)
Specific expression of an elastase–human growth hormone fusion gene in pancreatic acinar cells of transgenic mice (1985) (205)
Schoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteins. (2005) (205)
Role of Endothelin-1/Endothelin-A receptor-mediated signaling pathway in the aortic arch patterning in mice. (1998) (204)
Adult Apaf-1-deficient mice exhibit male infertility. (2000) (201)
T cells, but not thymic exposure to HLA-B27, are required for the inflammatory disease of HLA-B27 transgenic rats. (1996) (200)
Nkx2–5 transactivates the Ets-related protein 71 gene and specifies an endothelial/endocardial fate in the developing embryo (2009) (198)
Requirement of Tissue-Selective TBP-Associated Factor TAFII105 in Ovarian Development (2001) (195)
Disruption of ECE-1 and ECE-2 reveals a role for endothelin-converting enzyme-2 in murine cardiac development. (2000) (194)
Expression of insulin-like growth factor I in transgenic mice with elevated levels of growth hormone is correlated with growth. (1988) (191)
Tissue-specific expression of the rat pancreatic elastase I gene in transgenic mice (1984) (190)
Transgenic expression of the endothelin-B receptor prevents congenital intestinal aganglionosis in a rat model of Hirschsprung disease. (1998) (187)
A rapid whole-mount staining procedure for nuclei of mammalian embryos (1985) (184)
Overexpression of human low density lipoprotein receptors leads to accelerated catabolism of Lp(a) lipoprotein in transgenic mice. (1990) (181)
Expression of a Poly-Glutamine-Ataxin-3 Transgene in Orexin Neurons Induces Narcolepsy–Cataplexy in the Rat (2004) (177)
Partial correction of murine hereditary growth disorder by germ-line incorporation of a new gene (1984) (176)
Heterozygosity for the mouse Apex gene results in phenotypes associated with oxidative stress. (2001) (176)
Diet-induced hypercholesterolemia in mice: prevention by overexpression of LDL receptors. (1990) (176)
Expression of a microinjected immunoglobulin gene in the spleen of transgenic mice (1983) (172)
Additional human beta2-microglobulin curbs HLA-B27 misfolding and promotes arthritis and spondylitis without colitis in male HLA-B27-transgenic rats. (2006) (172)
Lin28b is sufficient to drive liver cancer and necessary for its maintenance in murine models. (2014) (168)
Transfer of the inflammatory disease of HLA-B27 transgenic rats by bone marrow engraftment (1993) (167)
Liver receptor homolog-1 regulates bile acid homeostasis but is not essential for feedback regulation of bile acid synthesis. (2008) (163)
Low density lipoprotein receptor-negative mice expressing human apolipoprotein B-100 develop complex atherosclerotic lesions on a chow diet: no accentuation by apolipoprotein(a). (1998) (162)
Two 3' sequences direct adult erythroid-specific expression of human beta-globin genes in transgenic mice. (1987) (158)
Development of porcine ova that were centrifuged to permit visualization of pronuclei and nuclei. (1985) (156)
Reconstitution of lipoprotein(a) by infusion of human low density lipoprotein into transgenic mice expressing human apolipoprotein(a). (1992) (154)
p53 genes function to restrain mobile elements (2016) (153)
Sustained somatic gene inactivation by viral transfer of Cre recombinase (1996) (145)
Conditional Expression of Mutant M-line Titins Results in Cardiomyopathy with Altered Sarcomere Structure* (2003) (143)
CDK5RAP2 regulates centriole engagement and cohesion in mice. (2010) (141)
Essential roles for the FE65 amyloid precursor protein‐interacting proteins in brain development (2006) (139)
Growth allometry of the organs in giant transgenic mice. (1987) (135)
Extracellular Domains of α-Neurexins Participate in Regulating Synaptic Transmission by Selectively Affecting N- and P/Q-Type Ca2+ Channels (2005) (135)
Bap1 is essential for kidney function and cooperates with Vhl in renal tumorigenesis (2014) (133)
Abnormal development of the apical ectodermal ridge and polysyndactyly in Megf7-deficient mice. (2005) (131)
Characterization of defective nucleotide excision repair in XPC mutant mice. (1997) (127)
A mutant human proinsulin is secreted from islets of Langerhans in increased amounts via an unregulated pathway. (1988) (123)
The Role of PTF1-P48 in Pancreatic Acinar Gene Expression* (2001) (123)
The homeodomain protein PDX1 is required at mid-pancreatic development for the formation of the exocrine pancreas. (2005) (122)
Disregulated glyceroneogenesis: PCK1 as a candidate diabetes and obesity gene (2004) (122)
Role of growth hormone in regulating T‐Dependent immune events in aged, nude, and transgenic rodents (1987) (122)
Defining the spermatogonial stem cell. (2004) (121)
Redundant functions of RIM1α and RIM2α in Ca2+‐triggered neurotransmitter release (2006) (121)
Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP (2010) (119)
Functional Dissection of Reelin Signaling by Site-Directed Disruption of Disabled-1 Adaptor Binding to Apolipoprotein E Receptor 2: Distinct Roles in Development and Synaptic Plasticity (2006) (116)
Neurexophilin binding to alpha-neurexins. A single LNS domain functions as an independently folding ligand-binding unit. (1998) (114)
Interplay between ChREBP and SREBP-1c coordinates postprandial glycolysis and lipogenesis in livers of mice[S] (2018) (114)
Tissue-specific, developmental, hormonal, and dietary regulation of rat phosphoenolpyruvate carboxykinase-human growth hormone fusion genes in transgenic mice (1992) (113)
Developmental regulation of alpha-fetoprotein genes in transgenic mice (1985) (112)
Modeling Renal Cell Carcinoma in Mice: Bap1 and Pbrm1 Inactivation Drive Tumor Grade. (2017) (110)
Expression of the chicken transferrin gene in transgenic mice (1983) (109)
Tissue-specific sorting of the human LDL receptor in polarized epithelia of transgenic mice (1990) (107)
Asialoglycoprotein receptor deficiency in mice lacking the minor receptor subunit. (1994) (105)
Novel developmental specificity in the nervous system of transgenic animals expressing growth hormone fusion genes (1985) (104)
Genetic Analysis of Mint/X11 Proteins: Essential Presynaptic Functions of a Neuronal Adaptor Protein Family (2006) (103)
Overexpression of low density lipoprotein (LDL) receptor eliminates LDL from plasma in transgenic mice. (1988) (101)
A role for Mints in transmitter release: Mint 1 knockout mice exhibit impaired GABAergic synaptic transmission (2003) (99)
Elastase I promoter directs expression of human growth hormone and SV40 T antigen genes to pancreatic acinar cells in transgenic mice. (1985) (99)
Low Blood Pressure in Endothelial Cell–Specific Endothelin 1 Knockout Mice (2010) (98)
Normal Sorting but Defective Endocytosis of the Low Density Lipoprotein Receptor in Mice with Autosomal Recessive Hypercholesterolemia* (2003) (97)
Neurexin Iα Is a Major α-Latrotoxin Receptor That Cooperates in α-Latrotoxin Action* (1998) (94)
Use of gene transfer to increase animal growth. (1985) (91)
The rat elastase I regulatory element is an enhancer that directs correct cell specificity and developmental onset of expression in transgenic mice (1987) (91)
Adipose Expression of the Phosphoenolpyruvate Carboxykinase Promoter Requires Peroxisome Proliferator-activated Receptor γ and 9-cis-Retinoic Acid Receptor Binding to an Adipocyte-specific Enhancer in Vivo* (1999) (91)
Sohlh2 Knockout Mice Are Male‐Sterile Because of Degeneration of Differentiating Type A Spermatogonia (2008) (91)
Progress on gene transfer in farm animals. (1987) (89)
Tissue-specific posttranslational processing of pre-prosomatostatin encoded by a metallothionein-somatostatin fusion gene in transgenic mice (1985) (88)
The expression of influenza virus hemagglutinin in the pancreatic β cells of transgenic mice results in autoimmune diabetes (1990) (86)
Fasting-induced hypothermia and reduced energy production in mice lacking acetyl-CoA synthetase 2. (2009) (85)
Cardiomyocyte-Specific Endothelin A Receptor Knockout Mice Have Normal Cardiac Function and an Unaltered Hypertrophic Response to Angiotensin II and Isoproterenol (2003) (84)
Synergistic interactions between XPC and p53 mutations in double-mutant mice: neural tube abnormalities and accelerated UV radiation-induced skin cancer (1996) (83)
Sox15 and Fhl3 transcriptionally coactivate Foxk1 and regulate myogenic progenitor cells (2007) (82)
Negative and positive selection of antigen-specific cytotoxic T lymphocytes affected by the α3 domain of MHC I molecules (1991) (81)
DHHC5 Interacts with PDZ Domain 3 of Post-synaptic Density-95 (PSD-95) Protein and Plays a Role in Learning and Memory* (2010) (81)
Heritable and stable gene knockdown in rats. (2006) (80)
Extracellular domains of alpha-neurexins participate in regulating synaptic transmission by selectively affecting N- and P/Q-type Ca2+ channels. (2005) (80)
Production of transgenic sheep with growth‐regulating genes (1989) (75)
Cytoplasmic sequence required for basolateral targeting of LDL receptor in livers of transgenic mice (1992) (74)
Expression of SREBP-1c Requires SREBP-2-mediated Generation of a Sterol Ligand for LXR in Livers of Mice (2017) (74)
ApoE Receptor 2 Controls Neuronal Survival in the Adult Brain (2006) (74)
Redundant functions of RIM1alpha and RIM2alpha in Ca(2+)-triggered neurotransmitter release. (2006) (73)
HLA-B27 in inbred and non-inbred transgenic mice. Cell surface expression and recognition as an alloantigen in the absence of human beta 2-microglobulin. (1988) (72)
Glucocorticoid regulation of metallothionein during murine development. (1986) (72)
Reelin protects against amyloid β toxicity in vivo (2015) (72)
Normal Development and Fertility of Knockout Mice Lacking the Tumor Suppressor Gene LRP1b Suggest Functional Compensation by LRP1 (2004) (72)
Mutagenesis of the human apolipoprotein B gene in a yeast artificial chromosome reveals the site of attachment for apolipoprotein(a). (1995) (71)
Expression and performance in transgenic pigs. (2020) (70)
Vascular and parenchymal amyloid pathology in an Alzheimer disease knock-in mouse model: interplay with cerebral blood flow (2014) (70)
Immunoglobulin kappa gene expression after stable integration. II. Role of the intronic MAR and enhancer in transgenic mice. (1989) (68)
Glyceroneogenesis comes of age (2002) (66)
The Specificity of Peptides Bound to Human Histocompatibility Leukocyte Antigen (HLA)-B27 Influences the Prevalence of Arthritis in HLA-B27 Transgenic Rats (1998) (66)
Blunted feedback suppression of SREBP processing by dietary cholesterol in transgenic mice expressing sterol-resistant SCAP(D443N). (1998) (65)
LRP1 integrates murine macrophage cholesterol homeostasis and inflammatory responses in atherosclerosis (2017) (64)
Genetic engineering of mammalian embryos. (1986) (61)
Deletion of ELOVL6 blocks the synthesis of oleic acid but does not prevent the development of fatty liver or insulin resistance[S] (2014) (60)
Correlation of Cecal Microflora of HLA-B27 Transgenic Rats with Inflammatory Bowel Disease (1998) (58)
Differential expression of α-fetoprotein genes on the inactive X chromosome in extraembryonic and somatic tissues of a transgenic mouse line (1986) (58)
APP interacts with LRP4 and agrin to coordinate the development of the neuromuscular junction in mice (2013) (58)
Analysis of SCAMP1 Function in Secretory Vesicle Exocytosis by Means of Gene Targeting in Mice* (1999) (58)
A mammalian acetate switch regulates stress erythropoiesis (2014) (58)
Differential requirements for cell-specific elastase I enhancer domains in transfected cells and transgenic mice. (1989) (57)
Correction: LDL receptor-related protein internalizes and degrades uPA-PAI-1 complexes and is essential for embryo implantation (1993) (57)
Integration, expression and germ-line transmission of growth-related genes in pigs. (1990) (57)
Overexpression of ABCG 5 and ABCG 8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol (2018) (56)
Genetic interaction between HAP1/REF-1 and p53 (1997) (55)
An endocrine-specific element is an integral component of an exocrine-specific pancreatic enhancer. (1993) (54)
Neuropeptide B-deficient mice demonstrate hyperalgesia in response to inflammatory pain. (2005) (54)
Cell-autonomous and nonautonomous actions of endothelin-A receptor signaling in craniofacial and cardiovascular development. (2003) (51)
Expression of human or bovine growth hormone gene with a mouse metallothionein-1 promoter in transgenic swine alters the secretion of porcine growth hormone and insulin-like growth factor-I. (1989) (50)
Cell‐specific expression of cytosolic phosphoenolpyruvate carboxykinase in transgenic mice (1992) (49)
dHAND-Cre transgenic mice reveal specific potential functions of dHAND during craniofacial development. (2003) (46)
Relative growth of the skull and postcranium in giant transgenic mice. (1990) (44)
Gonadotroph-specific expression of metallothionein fusion genes in pituitaries of transgenic mice. (1986) (44)
A chicken transferrin gene in transgenic mice escapes X-chromosome inactivation. (1987) (43)
Transgenic Mice Expressing Human ApoB95 and ApoB97 (1997) (43)
Relative contributions of apolipoprotein(a) and apolipoprotein-B to the development of fatty lesions in the proximal aorta of mice. (1995) (42)
Characterization of a Dazl‐GFP germ cell‐specific reporter (2009) (42)
A single element of the elastase I enhancer is sufficient to direct transcription selectively to the pancreas and gut (1994) (41)
Effects of nicotine on oviducal blood flow and embryo development in the rat. (1985) (41)
miR-26 suppresses adipocyte progenitor differentiation and fat production by targeting Fbxl19 (2019) (40)
Peripheral tolerance in mice expressing a liver-specific class I molecule: inactivation/deletion of a T-cell subpopulation. (1990) (39)
Autoimmune epididymoorchitis is essential to the pathogenesis of male-specific spondylarthritis in HLA-B27-transgenic rats. (2012) (39)
Metallothionein-vasopressin fusion gene expression in transgenic mice. Nephrogenic diabetes insipidus and brain transcripts localized to magnocellular neurons. (1989) (39)
Male and female germline specific expression of an EGFP reporter gene in a unique strain of transgenic rats. (2005) (39)
Cooperation between elements of an organ-specific transcriptional enhancer in animals (1995) (39)
The Human Leukocyte Antigen (HLA)-B27 Peptidome in Vivo, in Spondyloarthritis-susceptible HLA-B27 Transgenic Rats and the Effect of Erap1 Deletion * (2017) (38)
Differential splicing and glycosylation of Apoer2 alters synaptic plasticity and fear learning (2014) (37)
Effects of nicotine on uterine blood flow and intrauterine oxygen tension in the rat. (1981) (37)
High prevalence of colorectal cancer in HLA-B27 transgenic F344 rats with chronic inflammatory bowel disease. (1995) (36)
Defective dendritic cell (DC) function in a HLA-B27 transgenic rat model of spondyloarthropathy (SpA). (1995) (35)
Synaptic targeting domains of synapsin I revealed by transgenic expression in photoreceptor cells. (1994) (34)
C-terminal ECFP Fusion Impairs Synaptotagmin 1 Function (2005) (33)
Regulation of cytosolic phosphoenolpyruvate carboxykinase gene expression in adipocytes. (2003) (33)
Germ-line intrachromosomal recombination restores fertility in transgenic MyK-103 male mice. (1991) (32)
Neurexin I alpha is a major alpha-latrotoxin receptor that cooperates in alpha-latrotoxin action. (1998) (32)
Sterile Testis Complementation with Spermatogonial Lines Restores Fertility to DAZL-Deficient Rats and Maximizes Donor Germline Transmission (2009) (32)
RNA amplification and transcriptional profiling for analysis of stem cell populations (2003) (31)
Genetic Dissection of the Amyloid Precursor Protein in Developmental Function and Amyloid Pathogenesis*♦ (2010) (31)
Loss of Dis3l2 partially phenocopies Perlman syndrome in mice and results in up-regulation of Igf2 in nephron progenitor cells (2018) (30)
Nicotine Reduces Embryo Growth, Delays Implantation, and Retards Parturition in Rats (1979) (30)
Foxj3 transcriptionally activates Mef2c and regulates adult skeletal muscle fiber type identity. (2010) (30)
Promoter and enhancer elements from the rat elastase I gene function independently of each other and of heterologous enhancers (1987) (30)
Effect of the expression of a hepatocyte-specific MHC molecule in transgenic mice on T cell tolerance. (1990) (29)
Dlx5/6‐enhancer directed expression of Cre recombinase in the pharyngeal arches and brain (2003) (29)
Serotonin-induced disruption of implantation in the rat: II. Suppression of decidualization. (1983) (28)
Isoform 1 c of Sterol Regulatory Element Binding Protein Is Less Active Than Isoform 1 a in Livers of Transgenic Mice and in Cultured Cells (2013) (28)
reply: Leptin and diabetes in lipoatrophic mice (2000) (27)
Novel HY peptide antigens presented by HLA-B27. (1997) (27)
Characterization of psoriasiform and alopecic skin lesions in HLA-B27 transgenic rats. (1995) (27)
Analysis of genomic regions involved in regulation of the rabbit surfactant protein A gene in transgenic mice. (1999) (27)
Insertion, expression and physiology of growth-regulating genes in ruminants. (1990) (26)
PP2A-dependent disruption of centrosome replication and cytoskeleton organization in Drosophila by SV40 small tumor antigen (2008) (26)
Regulated Expression of α-Fetoprotein Genes in Transgenic Mice (1985) (26)
A simple method for counting nuclei in the preimplantation mouse embryo (1985) (25)
Rat MHC-linked peptide transporter alleles strongly influence peptide binding by HLA-B27 but not B27-associated inflammatory disease. (1996) (24)
Developmental Regulation of ox-Fetoprotein Genes in Transgenic Mice (24)
Embryonic neuronal death due to neurotrophin and neurotransmitter deprivation occurs independent of Apaf-1 (2001) (24)
INSERTION OF GROWTH HORMONE GENES INTO PIG EMBRYOS (1989) (24)
The International Journal of Developmental Biology: Preface (1998) (23)
Tissue-specific expression of kallikrein family transgenes in mice and rats. (1992) (23)
Transgenic mice expressing a human apolipoprotein[a] allele. (1999) (22)
Lrp4 Domains Differentially Regulate Limb/Brain Development and Synaptic Plasticity (2015) (22)
Hepatoblastoma modeling in mice places Nrf2 within a cancer field established by mutant β-catenin. (2016) (21)
Serotonin-induced disruption of implantation in the rat: I. Serum progesterone, implantation site blood flow, and intrauterine pO2. (1983) (20)
E6 and E7 expression from the HPV 18 LCR: development of genital hyperplasia and neoplasia in transgenic mice. (1995) (20)
Dramatic growth of mice that develop from eggs microinjected with metallothionein-growth hormone fusion genes. 1982. (1992) (19)
Deletion of ELOVL 5 leads to fatty liver through activation of SREBP-1 c in mice (2009) (19)
Estrogen regulation of the avian transferrin gene in transgenic mice (1986) (19)
Selective expression of trypsin fusion genes in acinar cells of the pancreas and stomach of transgenic mice. (1992) (19)
Egg culture: the foundation. (1998) (17)
Pathogenesis of Autosomal Dominant Hereditary Spastic Paraplegia (SPG6) Revealed by a Rat Model (2013) (16)
Somatostatin is targeted to the regulated secretory pathway of gonadotrophs in transgenic mice expressing a metallothionein-somatostatin gene. (1986) (16)
Tissue‐specific Expression of Pancreatic Genes in Transgenic Mice a (1986) (16)
Stimulation of growth hormone synthesis by glucose in islets of Langerhans isolated from transgenic mice. (1986) (15)
HLA-B27 Transgenic Mice as Potential Models of Human Disease (1990) (15)
A New Transgenic Mouse Model of Chronic Hyperglycemia (1994) (15)
Generation of transgenic mice from yeast artificial chromosome DNA that has been modified by gene targeting. (1996) (15)
Modulation of Mutant KrasG12D-Driven Lung Tumorigenesis In Vivo by Gain or Loss of PCDH7 Function (2018) (15)
Experimental Spondyloarthropathy in HLA-B27 Transgenic Rats (2013) (13)
A transgene coding for a human insulin analog has a mitogenic effect on murine embryonic beta cells. (1995) (13)
A new MHC locus that influences class I peptide presentation. (1997) (13)
Comparative analysis of SV40 17kT and LT function in vivo demonstrates that LT's C-terminus re-programs hepatic gene expression and is necessary for tumorigenesis in the liver (2012) (13)
Expression of Growth Hormone Genes in Transgenic Mice. (1985) (11)
High-Level Rearrangement and Transcription of Yeast Artificial Chromosome-Based Mouse Igκ Transgenes Containing Distal Regions of the Contig1 (2000) (11)
Leptin and diabetes in lipoatrophic mice. Authors' reply (2000) (10)
Transgenic progeny inherit tissue-specific expression of rat elastase I genes. (1986) (10)
Mesolimbic neuropeptide W coordinates stress responses under novel environments (2016) (10)
DHHC 5 INTERACTS WITH PDZ DOMAIN 3 OF POST-SYNAPTIC DENSITY-95 ( PSD-95 ) PROTEIN AND PLAYS A ROLE IN LEARNING AND MEMORY * (2010) (9)
The transcriptional regulatory strategy of the rat tissue kallikrein gene family. (1997) (9)
Novel HY peptide antigens presented by HLA-B27. (1999) (8)
Concomitant reduction in uterine blood flow and intrauterine oxygen tension in the rat following nicotine administration. (1983) (8)
Induction of hepatocyte proliferation and death by modulation of T-Antigen expression (2003) (7)
Studies of HLA-B27-associated disease. (1988) (7)
Effects of Nicotine on Conceptus Cell Proliferation and Oviductal/Uterine Blood Flow in the Rat (1981) (7)
O396 - Cytokine profiles and site-directed B27 mutation in the HLA-B27 transgenic rat (1996) (7)
Transgenic Mice Expressing Human ApoB95 and ApoB97 EVIDENCE THAT SEQUENCES WITHIN THE CARBOXYL-TERMINAL PORTION OF HUMAN apoB100 ARE IMPORTANT FOR THE ASSEMBLY OF LIPOPROTEIN(a)* (1997) (6)
[Fusion of vertebrae and the sacroiliac joint by cartilaginous tissue in HLA-B27 transgenic rats]. (1996) (6)
Neurexophilin Binding to α-Neurexins (1998) (6)
Analysis of genomic regions involved in regulation of the rabbit surfactant protein A gene in transgenic mice. (1999) (6)
Gene insertion: Role and limitations of technique in farm animals as a key to growth (1988) (5)
A substitution mutation in a conserved domain of mammalian acetate-dependent acetyl CoA synthetase 2 results in destabilized protein and impaired HIF-2 signaling (2019) (5)
Diet-induced hypercholesterolemia in mice (1990) (5)
Rat MHC-linked peptide transporter alleles strongly influence peptide binding by HLA-B27 but not B27-associated inflammatory disease. (1999) (5)
Regulated expression of alpha-fetoprotein genes in transgenic mice. (1985) (4)
The scientific contributions of Ralph L. Brinster to understanding mammalian embryo development and eukaryotic gene expression. (1988) (4)
Erratum: Production of transgenic rats by lentiviral transduction of male germ-line stem cells (Proceedings of the National Academy of Sciences of the United States of America (November 12, 2002) 23:99 (14931-14936)) (2002) (4)
Tolerance to Liver‐Specific Antigens (1991) (4)
Expression of a metallothionein-vasopressin fusion gene in transgenic mice produces hypervasopressinemia and manifestations of nephrogenic diabetes insipidus. (1988) (4)
Cleavage of pig embryos after labeling with fluorescent dyes (1985) (4)
Embryotoxic effects of serotonin during early pregnancy in the rat (1980) (4)
Overexpression of SREBP-1a in Mouse Adipose Tissue Produces Adipocyte Hypertrophy, Increased Fatty Acid Secretion, and Fatty Liver (2003) (3)
Sharing of an HLA-B27-restricted H-Y antigen between rat and mouse (2004) (3)
Accurate quantification of expression of transgenes marked with restriction endonuclease site polymorphisms by RT-PCR. (1998) (2)
NHE6-Depletion Corrects ApoE4-Mediated Synaptic Impairments and Reduces Amyloid Plaque Load (2021) (2)
The Interplay of Ethics, Animal Welfare, and IACUC Oversight on the Reproducibility of Animal Studies. (2017) (2)
NHE6 depletion corrects ApoE4-mediated synaptic impairments and reduces amyloid plaque load (2021) (2)
FGF21 Counteracts Alcohol Intoxication by Activating the Noradrenergic Nervous System (2023) (2)
Monoclonal antibody to the HLA class I alpha 3 domain inhibits T cell activation and prolongs cardiac allograft survival in HLA-transgenic mice. (1997) (2)
Mammalian acetate-dependent acetyl CoA synthetase 2 contains multiple protein destabilization and masking elements (2021) (2)
5-Hydroxytryptamine induced disruption of implantation in the rat: Possible modes of action (1980) (2)
Germline Saturation Mutagenesis Induces Skeletal Phenotypes in Mice (2020) (1)
Sharing of an HLA-B27-restricted H-Y antigen between rat and mouse. (2000) (1)
A new MHC locus that influences class I peptide presentation. (1999) (1)
16 Effects of Nicotine on Conceptus Cell Proliferation and Oviductal/Uterine Blood Flow in the Rat (1981) (1)
Author response: APP interacts with LRP4 and agrin to coordinate the development of the neuromuscular junction in mice (2013) (1)
Induction of cytotoxic CD8+ T cell after Yersinia infection of HLA-B27 transgenic rats: Evidence of restriction by rat class I MHC but not HLA-B27 (1997) (1)
Targeted expression of cloned genes in transgenic mice. (1987) (1)
SREBPs: Activators of cholesterol and monounsaturated fatty acid synthesis (1999) (1)
Gene transfer for increased animal growth (1988) (1)
The regulation of alpha-foetoprotein minigene expression in the germline of mice. (1986) (1)
Author response: Expression of SREBP-1c Requires SREBP-2-mediated Generation of a Sterol Ligand for LXR in Livers of Mice (2017) (1)
Author response: LRP1 integrates murine macrophage cholesterol homeostasis and inflammatory responses in atherosclerosis (2017) (1)
Acss2/HIF-2 signaling facilitates colon cancer growth and metastasis (2023) (1)
Analysis of mice expressing human apo(a) and apo B-100 transgenes (1994) (1)
Effects of nicotine on blastocyst development prior to implantation in the rat (1985) (1)
Serum iga does not reflect severity of colitis in the hla-b27 transgenic (TG) rat model of ibd: 33 (1997) (0)
The effect of nicotine on endometrial vascular permeability and pregnancy outcome in the rat (1981) (0)
Erratum: Novel HY peptide antigens presented by HLA-B27 (Journal of Immunology (1997) 159 (2750-2759)) (1999) (0)
Promoter andEnhancer Elements fromtheRatElastase IGene Function Independently ofEachOtherandofHeterologous Enhancers (1987) (0)
Erratum: A new MHC locus that influences class I peptide presentation (Immunity (1997) 7 (641-651)) (1999) (0)
Scanning electron microscopic observations of the early stages of implantation in the rat (1979) (0)
Abstract 4592: Exome sequencing of hepatoblastoma reveals recurrent mutations inNFE2L2. (2013) (0)
CORRECTIONS (2007) (0)
Low density lipoprotein receptor knockout mouse (1994) (0)
Metallothionein-Human GH Fusion Genes Stimulate Growth of Mice (2019) (0)
Rats transgenic for HLA-B27 and human β-2 microglobulin: A model for human spondyloarthropathies (1993) (0)
Apo(a) Expression in Transgenic Mice a (1994) (0)
Invariant Object Representation in Visual Cortex Unsupervised Natural Experience Rapidly Alters (2008) (0)
Effects of nicotine on conceptus development and oviductal/uterine blood flow in the rat (1979) (0)
Expression of the poly-glutamine-ataxin-3 transgene causes loss of orexin expression: A rat model of narcolepsy (2004) (0)
High plasma levels of immunoreactive somatostatin in transgenic mice expressing a metallothionein-somatostatin fusion gene. (1984) (0)
Effects of nicotine on zona pellucida loss and blastocyst development in the rat (1979) (0)
Sharing of an HLA-B27-restricted male H-Y antigen between rat and mouse (2000) (0)
genes in transgenic mice . carboxykinase-human growth hormone phosphoenolpyruvate hormonal , and dietary regulation of rat Tissue-specific , developmental (1992) (0)
Multiple sequences regulate human beta-globin gene expression in transgenic mice. (1987) (0)
Transgenic mice: A new approach to lipoprotein metabolism and atherogenesis (1992) (0)
The effects of 5-hydroxytryptamine and nicotine on blood flow and vascular permeability at the implantation site in the rat (1981) (0)
[Transgenic rats for HLA-B27 and human beta 2 microglobulin: a model of spondyloarthritis]. (1993) (0)
Vascular and parenchymal amyloid pathology in an Alzheimer disease knock-in mouse model: interplay with cerebral blood flow (2014) (0)
EGF , epithelium and Egg culturEgg lkjflajflajf 0 lajflajflkjf Egg culture : the foundation 833 Egg culture : the foundation (2001) (0)
Catabolism Dependence of Mouse Embryonic Stem Cells on Threonine (2012) (0)
Retraction: Sharing of an HLA-B27-restricted male H-Y antigen between rat and mouse (Immunogenetics (1993) 38 (351-358)) (2000) (0)
Abstract A17: Silencing of Nuclear factor (erythroid-derived 2)-like 2 (NFE2L2) impairs growth and proliferation of hepatoblastoma cells (2014) (0)
Hepatic ribosomal protein S6 (Rps6) insufficiency results in failed bile duct development and loss of hepatocyte viability; a ribosomopathy-like phenotype that is partially p53-dependent (2023) (0)
O4-05-07 FE65 amyloid precursor-protein binding proteins are essential for brain development (2006) (0)
Erratum: Rat MHC-linked peptide transporter alleles strongly influence peptide binding by HLA-B27 but not B-27-associated inflammatory disease (Journal of Immunology (1996) 156 (1661-1667)) (1999) (0)
Enteric neuroblast-specific expression of endothelin-b receptors allows normal ens development in the aganglionosis rat: 3 (1997) (0)
The regulation of α-foetoprotein minigene expression in the germline of mice (1986) (0)
Normal brain development in Lrp4 ECD/ECD and Lrp4 -/- mice. (2015) (0)
The ldl receptor supergene family (1992) (0)
Author response: NHE6 depletion corrects ApoE4-mediated synaptic impairments and reduces amyloid plaque load (2021) (0)
HLA-B27 transgenic rats: An animal model for human spondyloarthropathies (1994) (0)
Inflammatory Disease in B27/hβ2M Transgenic Rats: An Animal Model of B27-Associated Human Disorders (1992) (0)
W13.317 Characterization of LRP1b, a large member of the LDL receptor family and putative tumor suppressor, in the mouse (2004) (0)

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