Richard E. Pagano
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Biology
Richard E. Pagano's Degrees
- PhD Cell Biology University of California, San Francisco
- Bachelors Biology University of California, Berkeley
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(Suggest an Edit or Addition)Richard E. Pagano's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Pathways of clathrin-independent endocytosis (2007) (1485)
- Use of resonance energy transfer to monitor membrane fusion. (1981) (1190)
- A novel fluorescent ceramide analogue for studying membrane traffic in animal cells: accumulation at the Golgi apparatus results in altered spectral properties of the sphingolipid precursor (1991) (457)
- Ultrastructural identification of uncoated caveolin-independent early endocytic vehicles (2005) (453)
- Rab proteins mediate Golgi transport of caveola-internalized glycosphingolipids and correct lipid trafficking in Niemann-Pick C cells. (2002) (435)
- Interactions of liposomes with mammalian cells. (1978) (376)
- Sphingomyelin synthesis in rat liver occurs predominantly at the cis and medial cisternae of the Golgi apparatus. (1990) (327)
- Clathrin-dependent and -independent internalization of plasma membrane sphingolipids initiates two Golgi targeting pathways (2001) (324)
- A vital stain for the Golgi apparatus. (1985) (313)
- Cholesterol modulates membrane traffic along the endocytic pathway in sphingolipid-storage diseases (1999) (294)
- Selective stimulation of caveolar endocytosis by glycosphingolipids and cholesterol. (2004) (288)
- Defining lipid transport pathways in animal cells. (1985) (264)
- Intracellular translocation of fluorescent sphingolipids in cultured fibroblasts: endogenously synthesized sphingomyelin and glucocerebroside analogues pass through the Golgi apparatus en route to the plasma membrane (1985) (260)
- Determination of the intracellular sites and topology of glucosylceramide synthesis in rat liver. (1991) (254)
- Selective caveolin-1-dependent endocytosis of glycosphingolipids. (2003) (244)
- Molecular trapping of a fluorescent ceramide analogue at the Golgi apparatus of fixed cells: interaction with endogenous lipids provides a trans-Golgi marker for both light and electron microscopy (1989) (241)
- Glycosphingolipids Internalized via Caveolar-related Endocytosis Rapidly Merge with the Clathrin Pathway in Early Endosomes and Form Microdomains for Recycling* (2003) (239)
- Transbilayer movement of fluorescent analogs of phosphatidylserine and phosphatidylethanolamine at the plasma membrane of cultured cells. Evidence for a protein-mediated and ATP-dependent process(es). (1987) (226)
- Endocytic trafficking routes of wild type and DeltaF508 cystic fibrosis transmembrane conductance regulator. (2004) (221)
- Intracellular transport and metabolism of sphingomyelin. (1991) (221)
- Ligand-dependent and -independent transforming growth factor-beta receptor recycling regulated by clathrin-mediated endocytosis and Rab11. (2004) (220)
- Transforming growth factor-beta activation of phosphatidylinositol 3-kinase is independent of Smad2 and Smad3 and regulates fibroblast responses via p21-activated kinase-2. (2005) (220)
- Measurement of spontaneous transfer and transbilayer movement of BODIPY-labeled lipids in lipid vesicles. (1997) (216)
- Both Sphingolipids and Cholesterol Participate in the Detergent Insolubility of Alkaline Phosphatase, a Glycosylphosphatidylinositol-anchored Protein, in Mammalian Membranes (*) (1995) (197)
- Abnormal transport along the lysosomal pathway in mucolipidosis, type IV disease. (1998) (197)
- Lipid recycling between the plasma membrane and intracellular compartments: transport and metabolism of fluorescent sphingomyelin analogues in cultured fibroblasts (1989) (195)
- Interaction of phospholipid vesicles with cultured mammalian cells. (1975) (169)
- Sphingolipid metabolism in cultured fibroblasts: microscopic and biochemical studies employing a fluorescent ceramide analogue. (1983) (167)
- Insertion of fluorescent phospholipids into the plasma membrane of a mammalian cell. (1980) (166)
- Transport of a fluorescent phosphatidylcholine analog from the plasma membrane to the Golgi apparatus (1984) (158)
- Pneumocystis carinii Cell Wall β-Glucan Induces Release of Macrophage Inflammatory Protein-2 from Alveolar Epithelial Cells via a Lactosylceramide-mediated Mechanism* (2003) (158)
- Regulation of Endocytic Recycling of KCNQ1/KCNE1 Potassium Channels (2007) (156)
- Elevated endosomal cholesterol levels in Niemann-Pick cells inhibit rab4 and perturb membrane recycling. (2004) (152)
- Internalization and sorting of a fluorescent analogue of glucosylceramide to the Golgi apparatus of human skin fibroblasts: utilization of endocytic and nonendocytic transport mechanisms (1994) (147)
- Distinct mechanisms of clathrin-independent endocytosis have unique sphingolipid requirements. (2006) (145)
- Niemann-Pick C variant detection by altered sphingolipid trafficking and correlation with mutations within a specific domain of NPC1. (2001) (143)
- Phosphorylation, transbilayer movement, and facilitated intracellular transport of diacylglycerol are involved in the uptake of a fluorescent analog of phosphatidic acid by cultured fibroblasts. (1985) (143)
- Humanin is expressed in human vascular walls and has a cytoprotective effect against oxidized LDL-induced oxidative stress. (2010) (139)
- Broad screening test for sphingolipid-storage diseases (1999) (130)
- Membrane microdomains, caveolae, and caveolar endocytosis of sphingolipids (Review) (2006) (127)
- Sorting of an internalized plasma membrane lipid between recycling and degradative pathways in normal and Niemann-Pick, type A fibroblasts (1990) (121)
- Ceramide As a Modulator of Endocytosis (*) (1995) (120)
- Mutant huntingtin inhibits clathrin-independent endocytosis and causes accumulation of cholesterol in vitro and in vivo. (2006) (116)
- Use of Bodipy-labeled sphingolipid and cholesterol analogs to examine membrane microdomains in cells (2008) (116)
- Membrane Traffic in Sphingolipid Storage Diseases (2000) (113)
- Role of deformation-induced lipid trafficking in the prevention of plasma membrane stress failure. (2002) (113)
- Interaction of phospholipid vesicles with cultured mammalial cells. I. Characteristics of uptake (1975) (113)
- Resonance energy transfer assay of protein-mediated lipid transfer between vesicles. (1983) (109)
- A series of fluorescent N-acylsphingosines: synthesis, physical properties, and studies in cultured cells. (1988) (108)
- Resonance energy transfer microscopy: observations of membrane-bound fluorescent probes in model membranes and in living cells (1986) (108)
- Lipid transport during mitosis. Alternative pathways for delivery of newly synthesized lipids to the cell surface. (1989) (107)
- Rapid appearance of newly synthesized phosphatidylethanolamine at the plasma membrane. (1983) (103)
- Effects of a sphingolipid synthesis inhibitor on membrane transport through the secretory pathway. (1992) (102)
- Endocytosis and sorting of glycosphingolipids in sphingolipid storage disease. (2002) (102)
- Elevated lysosomal pH in Mucolipidosis type IV cells. (1999) (102)
- Phospholipid asymmetry in LM cell plasma membrane derivatives: polar head group and acyl chain distributions. (1978) (102)
- Glucosylceramide modulates membrane traffic along the endocytic pathway Published, JLR Papers in Press, August 16, 2002. DOI 10.1194/jlr.M200232-JLR200 (2002) (101)
- Lipid traffic in eukaryotic cells: mechanisms for intracellular transport and organelle-specific enrichment of lipids. (1990) (99)
- Regulation of caveolar endocytosis by syntaxin 6-dependent delivery of membrane components to the cell surface (2006) (98)
- Deformation-induced lipid trafficking in alveolar epithelial cells. (2001) (97)
- Protein transduction of Rab9 in Niemann‐Pick C cells reduces cholesterol storage (2005) (95)
- Changes in the spectral properties of a plasma membrane lipid analog during the first seconds of endocytosis in living cells. (1997) (93)
- The glycosphingolipid, lactosylceramide, regulates beta1-integrin clustering and endocytosis. (2005) (92)
- Sphingolipid Storage Induces Accumulation of Intracellular Cholesterol by Stimulating SREBP-1 Cleavage* (2003) (90)
- Determination of the transbilayer distribution of fluorescent lipid analogues by nonradiative fluorescence resonance energy transfer. (1992) (90)
- Inhibition of glycoprotein traffic through the secretory pathway by ceramide. (1993) (89)
- Transbilayer movement of a fluorescent phosphatidylethanolamine analogue across the plasma membranes of cultured mammalian cells. (1985) (89)
- Formation of asymmetric phospholipid membranes via spontaneous transfer of fluorescent lipid analogues between vesicle populations. (1981) (88)
- Oligomerization and Topology of the Golgi Membrane Protein Glucosylceramide Synthase* (1999) (87)
- Kinetics of soluble lipid monomer diffusion between vesicles. (1981) (85)
- Spherical lipid bilayer membranes: electrical and isotopic studies of ion permeability. (1968) (83)
- Endocytic trafficking of glycosphingolipids in sphingolipid storage diseases. (2003) (81)
- Isolation and characterization of lipid microdomains from apical and basolateral plasma membranes of rat hepatocytes (2006) (78)
- A fluorescent derivative of ceramide: physical properties and use in studying the Golgi apparatus of animal cells. (1989) (77)
- Physical chemistry of lipid films at the air-water interface. II. Binary lipid mixtures. The principles governing miscibility of lipids in surfaces. (1972) (76)
- Differential Effects of Modification of Membrane Cholesterol and Sphingolipids on the Conformation, Function, and Trafficking of the G Protein-coupled Cholecystokinin Receptor* (2005) (72)
- Purification and Characterization of UDP-glucose:Ceramide Glucosyltransferase from Rat Liver Golgi Membranes (*) (1996) (71)
- Intracellular translocation and metabolism of a fluorescent phosphatidic acid analogue in cultured fibroblasts. (1983) (71)
- Use of BODIPY‐labeled Sphingolipids to Study Membrane Traffic along the Endocytic Pathway a (1998) (70)
- Misassembled mutant ΔF508 CFTR in the distal secretory pathway alters cellular lipid trafficking (2006) (69)
- Intracellular distribution of lipophilic fluorescent probes in mammalian cells. (1977) (66)
- Human remyelination promoting antibody inhibits apoptotic signaling and differentiation through Lyn kinase in primary rat oligodendrocytes (2010) (64)
- Macrophage Internalization of Fungal β-Glucans Is Not Necessary for Initiation of Related Inflammatory Responses (2005) (63)
- What is the fate of diacylglycerol produced at the Golgi apparatus? (1988) (63)
- Type II Transforming Growth Factor-β Receptor Recycling Is Dependent upon the Clathrin Adaptor Protein Dab2 (2010) (62)
- Phase Transitions and Heterogeneity in Lipid Bilayers (1973) (61)
- Metabolism and intracellular localization of a fluorescently labeled intermediate in lipid biosynthesis within cultured fibroblasts (1981) (60)
- Up-regulation of Glucosylceramide Synthase Expression and Activity during Human Keratinocyte Differentiation* (1998) (60)
- Use of fluorescent sphingolipid analogs to study lipid transport along the endocytic pathway. (2005) (59)
- Membrane microdomains in hepatocytes: potential target areas for proteins involved in canalicular bile secretion Published, JLR Papers in Press, April 16, 2005. DOI 10.1194/jlr.M400412-JLR200 (2005) (58)
- Spatiotemporal dynamics of actin remodeling and endomembrane trafficking in alveolar epithelial type I cell wound healing. (2011) (56)
- Caveolar Endocytosis and Microdomain Association of a Glycosphingolipid Analog Is Dependent on Its Sphingosine Stereochemistry* (2006) (55)
- Inhibition of caveolar uptake, SV40 infection, and β1-integrin signaling by a nonnatural glycosphingolipid stereoisomer (2007) (54)
- Liposome-cell interactions. Studies of lipid transfer using isotopically asymmetric vesicles. (1979) (52)
- Cholesterol deprivation affects the fluorescence properties of a ceramide analog at the Golgi apparatus of living cells. (1993) (52)
- Detection of a phosphatidylinositol-specific phospholipase C at the surface of Swiss 3T3 cells and its potential role in the regulation of cell growth. (1990) (51)
- A millidyne film balance for measuring intermolecular energies in lipid films (1972) (51)
- Use of resonance energy transfer to study the kinetics of amphiphile transfer between vesicles. (1982) (49)
- Gangliosides and β1‐Integrin Are Required for Caveolae and Membrane Domains (2010) (48)
- The Golgi apparatus: insights from lipid biochemistry. (1990) (48)
- Applications of BODIPY-sphingolipid analogs to study lipid traffic and metabolism in cells. (2000) (48)
- Physical chemistry of lipid films at the air-water interface. I. Intermolecular energies in single-component lipid films. (1972) (48)
- ATP-dependent fusion of liposomes with the Golgi apparatus of perforated cells (1988) (47)
- Endocytic response of type I alveolar epithelial cells to hypertonic stress. (2011) (47)
- Reduced GM1 ganglioside in CFTR-deficient human airway cells results in decreased β1-integrin signaling and delayed wound repair. (2014) (47)
- Identification of Active Site Residues in Glucosylceramide Synthase (2001) (46)
- Development of a Rab9 transgenic mouse and its ability to increase the lifespan of a murine model of Niemann-Pick type C disease. (2009) (45)
- Interactions of phospholipid vesicles with murine lymphocytes. I. Vesicle-cell adsorption and fusion as alternate pathways of uptake. (1978) (44)
- Cryptosporidium parvum infects human cholangiocytes via sphingolipid‐enriched membrane microdomains (2006) (44)
- Capping of a phospholipid analog in the plasma membrane of lymphocytes (1981) (43)
- Switching the targeting pathways of a therapeutic antibody by nanodesign. (2012) (43)
- A Chinese hamster ovary cell mutant defective in the non-endocytic uptake of fluorescent analogs of phosphatidylserine: isolation using a cytosol acidification protocol (1995) (42)
- Co-regulation of Caveolar and Cdc42-dependent Fluid Phase Endocytosis by Phosphocaveolin-1* (2010) (41)
- Intracellular transport of ceramide and its metabolites at the Golgi complex: insights from short-chain analogs. (1993) (40)
- Spherical lipid bilayer membranes. (1967) (40)
- Transport of ions across lipid monolayers. IV. Reduction of polarographic currents by spread monolayers (1973) (37)
- Glycosphingolipids mediate pneumocystis cell wall β-glucan activation of the IL-23/IL-17 axis in human dendritic cells. (2012) (36)
- Internalization and Sorting of Plasma Membrane Sphingolipid Analogues in Differentiating Oligodendrocytes (1999) (33)
- Visualization of peptides derived from liposome-encapsulated proteins in the trans-Golgi area of macrophages. (1997) (31)
- Emerging problems in the cell biology of lipids (1985) (29)
- Use of N-([1-14C]hexanoyl)-D-erythro-sphingolipids to assay sphingolipid metabolism. (1992) (28)
- Effects of the glucosphingolipid synthesis inhibitor, PDMP, on lysosomes in cultured cells. (1994) (26)
- Synthesis of fluorescent and radiolabeled analogues of phosphatidic acid. (1985) (24)
- A Phase II Study of Topical Ceramides for Cutaneous Breast Cancer (2003) (23)
- Histidine-193 of rat glucosylceramide synthase resides in a UDP-glucose- and inhibitor (D-threo-1-phenyl-2-decanoylamino-3-morpholinopropan-1-ol)-binding region: a biochemical and mutational study. (1999) (23)
- Use of N-[5-(5,7-dimethyl boron dipyrromethene difluoride-sphingomyelin to study membrane traffic along the endocytic pathway. (1999) (21)
- Using Fluorescent Sphingolipid Analogs to Study Intracellular Lipid Trafficking (2007) (21)
- Trigeminal-Taste Interaction in Palatability Processing (18)
- Interactions of phospholipid vesicles with murine lymphocytes. II. Correlation between altered surface properties and enhanced proliferative response. (1978) (18)
- Normal- and reverse-phase HPLC separations of fluorescent (NBD) lipids. (1986) (18)
- Intracellular translocation and metabolism of fluorescent lipid analogues in cultured mammalian cells (1983) (17)
- Methods for studying glucosylceramide synthase. (2000) (16)
- Primary alveolar epithelial cell surface membrane microdomain function is required for Pneumocystis β-glucan-induced inflammatory responses (2012) (15)
- Prominin-2 expression increases protrusions, decreases caveolae and inhibits Cdc42 dependent fluid phase endocytosis. (2013) (14)
- The molecular composition of some lipid bilayer membranes in aqueous solution (2005) (12)
- Phase separation in cholesterol—dipalmitoyl lecithin mixed films and the condensing effect (1973) (11)
- Introduction of antigenic phospholipids into the plasma membrane of mammalian cells: organization and antibody-induced lipid redistribution. (1978) (11)
- Millidyne Sensor for the Langmuir Film Balance (1970) (10)
- Role of Protein Kinase D in Golgi Exit and Lysosomal Targeting of the Transmembrane Protein, Mcoln1 (2012) (10)
- Stimulation of GLUT4 (glucose transporter isoform 4) storage vesicle formation by sphingolipid depletion. (2010) (9)
- Resonance energy transfer microscopy: visual colocalization of fluorescent lipid probes in liposomes. (1989) (9)
- Activation of 5-[125I]iodonaphthyl-1-azide via excitation of fluorescent (N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)) lipid analogs in living cells. A potential tool for identification of compartment-specific proteins and proteins involved in intracellular transport and metabolism of lipids. (1991) (9)
- Retrograde movement of membrane lipids from the Golgi apparatus to the endoplasmic reticulum of perforated cells: evidence for lipid recycling. (1993) (7)
- Sphingomyelin synthesis in endosomal compartments? (1995) (7)
- Density-dependent inhibition of cell growth is correlated with the activity of a cell surface phosphatidylinositol-specific phospholipase C. (1991) (6)
- Use of a fluorescent analog of CDP-DAG in human skin fibroblasts: characterization of metabolism, distribution, and application to studies of phosphatidylinositol turnover. (1997) (6)
- Proteomic identification of proteins translocated to membrane microdomains upon treatment of fibroblasts with the glycosphingolipid, C8‐β‐D‐lactosylceramide (2009) (6)
- Fluorescent Sphingomyelin Labels the Plasma Membrane of Cultured Fibroblasts (1984) (5)
- Elevated endosomal cholesterol in Niemann Pick cells inhibits rab 4 and perturbs membrane recycling (2004) (5)
- METABOLISM AND INTRACELLULAR DISTRIBUTION OF A FLUORESCENT ANALOGUE OF PHOSPHATIDIC ACID IN CULTURED FIBROBLASTS * (1983) (5)
- Physical chemistry of lipid films at the air-water interface. 3. The condensing effect of cholesterol. A critical examination of mixed-film studies. (1972) (5)
- Use of Rab GTPases to study lipid trafficking in normal and sphingolipid storage disease fibroblasts. (2005) (5)
- An improved synthesis of 7-nitrobenz-2-oxa-1,3-diazole analogs of CDP-diacylglycerol and phosphatidylinositol. (1991) (5)
- Synthesis and Properties of Fluorescent Analogs of Cytidine Diphosphate-Diacylglycerol and Phosphatidylinositol (1986) (3)
- Spherical lipid bilayers: Surface tension and contact angle measurements (1973) (3)
- Liposomes: clinical potential. (1978) (2)
- Use of Bodipy™-Labeled Sphingolipids to Study Membrane Traffic in Animal Cells (1996) (1)
- Viral Attachment Induces Rapid Recruitment of an Innate Immune Sensor (TRIM5α) to the Plasma Membrane (2013) (1)
- 476 Isolation and characterization of specialized microdomains of hepatocyte plasma membranes: Potential role in canalicular bile formation (2003) (1)
- Membrane traffic in animal cells: Metabolism and intracellular translocation of fluorescent lipids (1992) (1)
- INTERACTION OF PHOSPHOLIPID VESICLES WITH CULTURED M A M M A L I A N CELLS I. Characteristics of Uptake (2003) (1)
- Endocytic Trafficking of Glycosphingolipids in Sphingolipidoses (2006) (1)
- Short Communication Development of a Rab9 Transgenic Mouse and Its Ability to Increase the Lifespan of a Murine Model of Niemann-Pick Type C Disease (2008) (0)
- Back Cover: Switching the Targeting Pathways of a Therapeutic Antibody by Nanodesign (Angew. Chem. Int. Ed. 7/2012) (2012) (0)
- Glycosphingolipid Participation In The Activation Of The IL-23/IL-7 Axis In Human Dendritic Cells By Pneumocystis Beta-Glucan (2011) (0)
- Macrophage Internalization of Fungal (cid:2) -Glucans Is Not Necessary for Initiation of Related Inflammatory Responses (2005) (0)
- Identification of Active Site Residues in Glucosylceramide Synthase A NUCLEOTIDE-BINDING/CATALYTIC MOTIF CONSERVED WITH PROCESSIVE b -GLYCOSYLTRANSFERASES* (2001) (0)
- New connections linking sorting & trafficking of VEGFR2 from Golgi with angiogenesis (2009) (0)
- Gordon Research Conference on Lipid Metabolism Held in Meriden, New Hampshire on 17-21 June 1985. (1985) (0)
- Derives de ceramide (1993) (0)
- Sphingolipid metabolism in culture biochemical studies employing a fll (Golgi apparatus/sphingomyelin/cerebrosides/liposomes/fluorescenc (2016) (0)
- Liposomes: Clinical Potential (1978) (0)
- Pneumocystis Carinii β-glucan-induced Chemokine Secretion From Alveolar Epithelial Cells Requires Activation of Protein Kinase C and NF-κ (2003) (0)
- PL 9Role of sphingolipids in caveolar endocytosis (2008) (0)
- healingcurrents that guide cell migration to promote Airway epithelial wounds in rhesus monkey generate (2015) (0)
- USE OF FLUORESCENCE ENERGY TRANSFER TO MONITOR MEMBRANE FUSION (1981) (0)
- Rücktitelbild: Switching the Targeting Pathways of a Therapeutic Antibody by Nanodesign (Angew. Chem. 7/2012) (2012) (0)
- Pneumocystis Carinii Binds the Lung Epithelial Cell Glycosphingolipid Lactosylceramide, a Potential Novel Adhesion Receptor for the Organism. (2009) (0)
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