Richard E. Tashian

Richard E. Tashian's AcademicInfluence.com Rankings

Richard E. Tashian

Philosophy

#8307

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#11660

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#5344

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#6735

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Richard E. Tashian

Biology

#11234

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#14617

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Genetics

#1206

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#1307

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Molecular Biology

#1714

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#1743

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Biochemistry

#1840

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#1980

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Philosophy
Biology

Richard E. Tashian's Degrees

PhD Biochemistry University of California, Berkeley
Doctorate Medicine University of California, San Francisco

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Richard E. Tashian's Published Works

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Published Works

Carbonic anhydrase II deficiency identified as the primary defect in the autosomal recessive syndrome of osteopetrosis with renal tubular acidosis and cerebral calcification. (1983) (599)
Functional diversity, conservation, and convergence in the evolution of the alpha-, beta-, and gamma-carbonic anhydrase gene families. (1996) (541)
The carbonic anhydrases: Widening perspectives on their evolution, expression and function (1989) (388)
Carbonic anhydrase II deficiency in 12 families with the autosomal recessive syndrome of osteopetrosis with renal tubular acidosis and cerebral calcification. (1985) (300)
The Carbonic anhydrases : cellular physiology and molecular genetics (1991) (216)
Phylogenetic origins and adaptive evolution of avian and mammalian haemoglobin genes (1982) (175)
N-ethyl-N-nitrosourea-induced null mutation at the mouse Car-2 locus: an animal model for human carbonic anhydrase II deficiency syndrome. (1988) (156)
Genetics of the mammalian carbonic anhydrases. (1992) (124)
An improved method for the purification of carbonic anhydrase isozymes by affinity chromatography. (1975) (122)
The immunohistolocalization of carbonic anhydrase in rodent tissues. (1979) (120)
Immunocytochemical demonstration of carbonic anhydrase in human epithelial cells. (1982) (114)
Molecular basis of human carbonic anhydrase II deficiency. (1992) (106)
GENETIC VARIATION AND EVOLUTION OF THE CARBOXYLIC ESTERASES AND CARBONIC ANHYDRASES OF PRIMATE ERYTHROCYTES. (1965) (104)
Comparative distribution of carbonic anhydrase isozymes III and II in rodent tissues. (1990) (101)
Mice carrying a CAR-2 null allele lack carbonic anhydrase II immunohistochemically and show vascular calcification. (1989) (97)
Amino Acid Sequence Evidence on the Phylogeny of Primates and Other Eutherians (1982) (91)
Carbonic anhydrase (CA)-related proteins (CA-RPs), and transmembrane proteins with CA or CA-RP domains. (2000) (84)
Carbonic anhydrase II deficiency syndrome in a Belgian family is caused by a point mutation at an invariant histidine residue (107 His----Tyr): complete structure of the normal human CA II gene. (1991) (82)
Studies on the Physiological Variation Between Tropical and Temperate Zone Fiddler Crabs of the Genus UCA I. Thermal Death Limits (1959) (82)
Testosterone‐induced, sulfonamide‐resistant carbonic anhydrase isozyme of rat liver is indistinguishable from skeletal muscle carbonic anhydrase III (1981) (78)
Origins and Molecular Evolution of the Carbonic Anhydrase Isozymes a (1984) (78)
Intratribal genetic differentiation among the Yanomama Indians of southern Venezuela. (1967) (77)
GENETIC AND PHYLOGENETIC VARIATION IN THE DIFFERENT MOLECULAR FORMS OF MAMMALIAN ERYTHROCYTE CARBONIC ANHYDRASES * (1968) (72)
A splice junction mutation in intron 2 of the carbonic anhydrase II gene of osteopetrosis patients from Arabic countries (1992) (70)
Esterase and hydrase activity of carbonic anhydrase. I. From primate erythrocytes. (1964) (68)
Characterization of the human gene for a newly discovered carbonic anhydrase, CA VII, and its localization to chromosome 16. (1991) (67)
Inherited Variant of Erythrocyte Carbonic Anhydrase in Micronesians from Guam and Saipan (1963) (66)
Erythrocyte Glucose-6-Phosphate Dehydrogenase in Caucasians: New Inherited Variant (1964) (65)
Biochemical genetics of carbonic anhydrase. (1976) (64)
Biology and chemistry of the carbonic anhydrases. (1984) (62)
The catalytic properties of murine carbonic anhydrase VII. (1998) (59)
Inheritance of an erythrocyte acetylesterase variant in man. (1962) (56)
On the evolution and genetics of carbonic anhydrases I, II, and III. (1983) (52)
Structure and Evolutionary Origins of the Carbonic Anhydrase Multigene Family (1991) (51)
Differential Expression of the Carbonic Anhydrase Genes for CA VII (Car7) And CA-RP VIII (Car8) in Mouse Brain (1997) (49)
The deduced amino acid sequence of human carbonic anhydrase-related protein (CARP) is 98% identical to the mouse homologue. (1993) (49)
Erythrocyte carbonic anhydrase I: inherited deficiency in humans. (1977) (49)
Organization of the Mouse and Human Carbonic Anhydrase II Genes a (1984) (48)
The gene for human carbonic anhydrase II (CA2) is located at chromosome 8q22. (1987) (46)
The Value of Inherited Deficiencies of Human Carbonic Anhydrase Isozymes in Understanding Their Cellular Roles a (1984) (46)
New Genetically Determined Molecular Form of Erythrocyte Esterase in Man (1962) (45)
Hexokinase Isozyme Patterns of Human Erythrocytes and Leucocytes (1966) (45)
Hereditary variation of erythrocytic 6-phosphogluconate dehydrogenase. (1966) (45)
Characterization of a mutant human erythrocyte carbonic anhydrase: carbonic anhydrase Ic-Guam. The amino acid substitution and carboxylesterase and hydratase activities. (1966) (44)
Crystal structure of a zinc-activated variant of human carbonic anhydrase I, CA I Michigan 1: evidence for a second zinc binding site involving arginine coordination. (2002) (43)
Polymorphic gene for human carbonic anhydrase II: a molecular disease marker located on chromosome 8. (1983) (42)
Molecular Anthropology: Genes and Proteins in the Evolutionary Ascent of the Primates (1978) (42)
Evolutionarily conserved, "acatalytic" carbonic anhydrase-related protein XI contains a sequence motif present in the neuropeptide sauvagine: the human CA-RP XI gene (CA11) is embedded between the secretor gene cluster and the DBP gene at 19q13.3. (1998) (41)
The Seminole Indians of Florida: morphology and serology. (1970) (41)
Evidence for linkage of carbonic anhydrase isozyme genes in the pig-tailed macaque, Macaca nemestrina. (1973) (41)
Multiple Forms of Esterases from Human Erythrocytes.∗ (1961) (40)
Structure and exon to protein domain relationships of the mouse carbonic anhydrase II gene. (1985) (39)
Evolution of Structure and Function in the Carbonic Anhydrase Isozymes of Mammals (1980) (38)
Oligodendrocytes express a normal phenotype in carbonic anhydrase II‐deficient mice (1989) (38)
The nucleotide sequence and derived amino acid sequence of cDNA coding for mouse carbonic anhydrase II. (1983) (38)
Immunohistochemical localization of carbonic anhydrase I and II in eccrine sweat glands from control subjects and patients with cystic fibrosis. (1983) (38)
Carbonic anhydrase II deficiency: single-base deletion in exon 7 is the predominant mutation in Caribbean Hispanic patients. (1994) (37)
Genetic variation and evolution in the red cell carbonic anhydrase isozymes of macaque monkeys (1971) (36)
Purification and properties of carbonic anhydrase from sheep erythrocytes. (1971) (35)
Amino acid sequence of sheep carbonic anhydrase C. (1974) (35)
Carbonic anhydrase II is induced in HL‐60 cells by 1,25‐dihydroxyvitamin D3: A model for osteoclast gene regulation (1989) (32)
The relation of oxygen consumption to temperature in some tropical, temperate and boreal anuran amphibians (1957) (32)
Molecular genetics of carbonic anhydrase isozymes. (1987) (31)
Inhibition of brain glutamic acid decarboxylase by phenylalanine, valine, and leucine derivatives: a suggestion concerning the etiology of the neurological defect in phenylketonuria and branched-chain ketonuria. (1961) (31)
Inherited variants of human red cell carbonic anhydrases. (1980) (30)
Membrane-associated carbonic anhydrase activity in the kidney of CA II-deficient mice. (1992) (30)
Nucleotide sequence of human liver carbonic anhydrase II cDNA. (1987) (29)
Further studies on the Xavante Indians. V. Genetic variability in some serum and erythrocyte enzymes, hemoglobin, and the urinary excretion of beta-aminoisobutyric acid. (1967) (29)
Properties of carbonic anhydrase isozymes isolated from porcine erythrocytes. (1970) (29)
Expression of the acatalytic carbonic anhydrase VIII gene, Car8, during mouse embryonic development (1997) (29)
The electrophoretic phenotypes of red cell phosphoglucomutase, adenylate kinase, and acid phosphatase n the American Negro. (1967) (28)
Carbonic anhydrase activity of intact carbonic anhydrase II-deficient human erythrocytes. (1988) (26)
Thermal inactivation studies of normal and variant human erythrocyte carbonic anhydrases by using a sulphonamide-binding assay. (1974) (25)
Evolution, structure, and expression of the carbonic anhydrase multigene family. (1990) (24)
MOLECULAR SYSTEMATICS AND CLINAL VARIATION IN MACAQUES (1975) (24)
Carbonic anhydrase III isoenzyme from human and bovine muscle [proceedings]. (1978) (23)
Molecular analysis of G+C-rich upstream sequences regulating transcription of the human carbonic anhydrase II gene (1987) (23)
Amino acid sequence of rabbit carbonic anhydrase II. (1978) (22)
Mutation creates an open reading frame within the 5' untranslated region of macaque erythrocyte carbonic anhydrase (CA) I mRNA that suppresses CA I expression and supports the scanning model for translation. (1992) (21)
Expression of mouse carbonic anhydrase VII in E. coli and demonstration of its CO2 hydrase activity. (1996) (20)
Comparison of the 5' regions of human and mouse carbonic anhydrase II genes and identification of possible regulatory elements. (1985) (20)
A geographic variation in the serum transferrin and red cell phosphoglucomutase polymorphisms of chimpanzees. (1969) (19)
Unexpected expression of carbonic anhydrase I and selenium‐binding protein as the only major non‐heme proteins in erythrocytes of the subterranean mole rat (Spalax ehrenbergi) (1998) (18)
A WIDESPREAD SILENT POLYMORPHISM OF HUMAN CARBONIC ANHYDRASE III (31 ILE ↔ VAL): IMPLICATIONS FOR EVOLUTIONARY GENETICS (1983) (18)
Red Cells Genetically Deficient in Carbonic Anhydrase II Have Elevated Levels of a Carbonic Anhydrase Indistinguishable from Muscle CA III a (1984) (16)
Phenylpyruvic Acid as a Possible Precursor of o-Hydroxyphenylacetic Acid in Man (1959) (16)
Novel inhibition of carbonic anhydrase isozymes I, II and III by carbamoyl phosphate (1984) (15)
Enzymatic synthesis of carbonic anhydrases by human reticulocytes. (1969) (15)
Characterization of two new variants of red cell carbonic anhydrase in the British population: CA Ie Portsmouth and CA Ie Hull. (1972) (14)
Differential Inhibition of Red Cell Carbonic Anhydrase Isozymes in Hyperthyroidism (1970) (14)
Promoter activity of carbonic anhydrase II regulatory regions in cultured renal proximal tubular cells. (1998) (14)
Avifauna of the Catemaco Basin of Southern Veracruz, Mexico (1959) (13)
Evolution of Carbonic Anhydrase in Primates and Other Mammals (1976) (13)
Nesting behavior of the crested oropendola (Psarocolius decumanus) in Northern Trinidad, B.W.I (1957) (13)
Amino acid sequence of the coat protein subunit in satellite tobacco necrosis virus. (1981) (13)
Isoenzymes of carbonic anhydrase I from primate red blood cells. (1971) (12)
EVOLUTION OF THE CARBONIC ANHYDRASE ISOZYMES (1975) (12)
The amino acid sequence of carbonic anhydrase I from the rhesus macaque. (1980) (12)
Differential rates of evolution in the carbonic anhydrase isozymes of catarrhine primates (1972) (12)
Genetic variation in the carbonic anhydrase isozymes of macaque monkeys. 3. Biosynthesis of carbonic anhydrases in bone marrow erythroid cells and peripheral blood reticulocytes of Macaca nemestria. (1973) (11)
Ultrastructural localization of carbonic anhydrase in gastric parietal cells with the immunoglobulin-enzyme bridge method (1980) (11)
Variation in the primary structure of carbonic anhydrase B in man, great apes, and old world monkeys. (1970) (11)
Carbonic Anhydrase Isozymes in Cultured Friend Leukemic Cells 1 (1977) (11)
A semi-quantitative method for determining the levels of carbonic anhydrase isozymes in individual red blood cells. (1971) (11)
Some Birds from the Palenque Region of Northeastern Chiapas, Mexico (1952) (11)
Notes on Mammals from Northern Chiapas, Mexico (1954) (10)
Genetic variation in the carbonic anhydrase isozymes of macaque monkeys. II. Inheritance of red cell carbonic anhydrase levels in different carbonic anhydrase I genotypes of the pig-tailed macaque, Macaca nemestrina (1973) (10)
Characterization of the genes encoding carbonic anhydrase I of chimpanzee and gorilla: comparative analysis of 5' flanking erythroid-specific promoter sequences. (1993) (9)
Assignment of the gene for human carbonic anhydrase VIII(CA8) to chromosome 8q11-->q12. (1995) (9)
Features of Gene Structure, Organization, and Expression That Are Providing Unique Insights into Molecular Evolution and Systematics (1982) (9)
Effect of Phenylalanine Metabolites on Urinary Excretion of Indole-3-acetic Acid and 5-Hydroxyindole-3-acetic Acid in Man.∗ (1960) (9)
The Birds of Southeastern Guatemala (1953) (8)
Absence or Reduction of Carbonic Anhydrase II in the Red Cells of the Beluga Whale and Llama: Implications for Adaptation to Hypoxia (2000) (8)
Activation of mammalian skeletal-muscle carbonic anhydrase III by arginine modification (1984) (8)
Active Site Studies on Muscle Carbonic Anhydrase III a (1984) (7)
DNA polymorphism in the 5′ flanking region of the human carbonic anhydrase II gene on chromosome 8 (2004) (7)
Thyroid Status and Carbonic Anhydrase Levels in Mouse Erythrocytes 1 (1976) (7)
Dissociation constants for carbonic anhydrase--sulfonamide binding by high-performance liquid chromatography. (1984) (7)
Problems in the chemical diagnosis of some hereditary metabolic diseases. (1961) (6)
Progress in Molecular Anthropology (1976) (6)
Expression of carbonic anhydrase II (CA II) promoter-reporter fusion genes in multiple tissues of transgenic mice does not replicate normal patterns of expression indicating complexity of CA II regulationin vivo (1995) (6)
Characterization of a mutant human erythrocyte carbonic anhydrase: Carbonic anhydrase IcGuam (1966) (6)
The specific distinctions of the fiddler crabs Uca pugnax (Smith) and Uca rapax (Smith) at their zone of overlap in Northeastern Florida (1958) (6)
Quantitative genetic variation in carbonic anhydrase isozymes from tissues of the pig-tailed macaque, Macaca nemestrina (1971) (6)
The proteolytic degradation of normal and variant human carbonic anhydrase isozymes by alpha-chymotrypsin. (1981) (6)
Marked zinc activation of ester hydrolysis by a mutation, 67‐His (CAT) to Arg (CGT), in the active site of human carbonic anhydrase I (1994) (5)
Substitution of lysine for threonine at position 100 in human carbonic anhydrase Id Michigan. (1973) (5)
PCR detection of a BstNI RSP in exon 6 of the human carbonic anydrase II locus, CA2. (1991) (5)
Hexokinase isozyme patterns of human erythrocytes and leucocytes. (1966) (5)
Beta-aminoisobutyric acid (BAIB) excretion in urine of residents of eight communities in the states of Michoacán and Oaxaca, Mexico. (1969) (5)
A radioimmunoassay for quantifying carbonic anhydrase isozymes in crude lysates (1970) (4)
Differential excretion of D-phenylalanine in man. (1957) (4)
Ectopic expression of chloramphenicol acetyltransferase (CAT) in the cerebellum in mice transgenic for a carbonic anhydrase II promoter‐CAT construct that is without apparent phenotypic effect (1990) (4)
Determination of L-tyrosine as tyramine in urine. (1957) (4)
Genetic variation in the carbonic anhydrase isozymes of macaque monkeys. I. The radioimmunosorbent assay (1973) (4)
Chemical characterization of a new Japanese variant of carbonic anhydrase I, CA INagasaki 1 (76 Arg→Gln) (2004) (4)
Effect of Metabolic Acidosis on Hydrogen Ion Excretion in a Pigtail Macaque with Erythrocyte Carbonic Anhydrase I Deficiency 1 (1981) (4)
Characterization of the gene encoding carbonic anhydrase I from the pigtail macaque. (1995) (4)
Active-site modification of chicken carbonic anhydrase III (1988) (3)
Amino acid substitution and chemical characterization of a Japanese variant of carbonic anhydrase I: CA I Hiroshima-1 (86 Asp → Gly) (1981) (3)
Biochemical characterization of the human carbonic anhydrase variant CA ih Hiroshima (1976) (3)
Keeping pace with a fast enzyme: steps and missteps. (2000) (3)
Evolutionary perspectives and the new genetics. Proceedings of an international symposium honoring Dr. James V. Neel. Ann Arbor, Michigan, June 17-18, 1985. (1986) (3)
Cross-reactions among carbonic anhydrases I, II, and III studied by binding tests and with monoclonal antibodies (1982) (3)
Lark Sparrow (Chondestes grammacus) on Bimini, Bahamas, B.W.I. (1956) (3)
Characterization of a new variant of human red cell carbonic anhydrase I, CA if London (Glu-102→Lys) (1973) (2)
A widespread silent polymorphism of human carbonic anhydrase III (31 Ile in equilibrium Val): implications for evolutionary genetics. (1983) (2)
Variation in coding exons of two electrophoretic alleles at the pigtail macaque carbonic anhydrase I locus as determined by direct, double-stranded sequencing of polymerase chain reaction (PCR) products (1992) (2)
The new variant carbonic anhydrase in the Japanese: CAINagasaki 1(76 Arg replaced by Gln) and CAIHiroshima 2. (1980) (2)
Characterization of a new variant of human red cell carbonic anhydrase I, CA If London (Glu-102 leads to Lys). (1973) (2)
Effect of chlorthalidone binding on the electrophoretic properties of human red cell carbonic anhydrase isozymes. (1972) (2)
PCR detection of the TAQ1 polymorphism at the CA2 locus. (1990) (2)
Bone marrow transplantation demonstrates that carbonic anhydrase II deficiency limited to bone marrow-derived cells affects ammonium chloride tolerance in mice. (1994) (2)
Activation of carbonic anhydrase III by active-site modification (1984) (2)
Residue (107 His--Tyr): Complete Structure of the Normal Human CA 11 Gene (2006) (1)
Introductory Remarks at the Beginning of Session III (1972) (1)
Genetic Variation in the Carbonic Anhydrase Isozymes (1973) (1)
Genetic control of quantitative variation in carbonic anhydrase isozymes of mammals. I. The concentration within single erythrocytes of the mouse (1977) (1)
Genetic variation in the carbonic anhydrase isozymes of macaque monkeys. IV. Degradation by heat and proteolysis of normal and variant carbonic anhydrase isozymes of Macaca nemestrina. (1984) (1)
Individual variability in the metabolism of D-phenylalanine in human subjects. (1959) (1)
Some Factors Affecting Differential Excretion of D-Phenylalanine in Man.∗ (1957) (1)
Reactivation and immunological studies on a Japanese variant of red cell carbonic anhydrase I, CA I Hiroshima. (1982) (1)
Instructions for the preparation of gene mapping reports (1995) (1)
The nucleotide sequence and derived amino acid sequence of eDNA coding for mouse carbonic anhydrase (2004) (1)
PCR amplification of genomic DNA from a 24 year old lysate derived from washed human erythrocytes. (1991) (1)
Carbonic Anhydrase-Related Protein XI: Structure of the Gene in the Greater False Vampire Bat (Megaderma lyra) Compared with Human and Domestic Pig (2013) (1)
Molecular Anthropology@@@Molecular Anthropology: Genes and Proteins in the Evolutionary Ascent of Primates. (1978) (1)
Isolation of a 40 kb cosmid clone containing a portion of the mouse carbonic anhydrase ii gene. Abstr. (1983) (0)
Chemical characterization of a new Japanese variant of carbonic anhydrase I, CA INagasaki 1 (76 arg leads to gln). (1979) (0)
Opening Remarks (1984) (0)
ANNALS BY VOLUME (1987) (0)
METHOD FOR DETERMINING THE LEVELS OF CARBONIC ANHYDRASE ISOZYMES IN INDIVIDUAL RED BLOOD CELLS (1971) (0)
Contents, Vol. 44, 1987 (1987) (0)
Variation in coding exons of two electrophoretic alleles at the pigtail macaque carbonic anhydrase I locus as determined by direct, double-stranded sequencing of polymerase chain reaction (PCR) products (1992) (0)
THE AMINO ACID SEQUENCE OF CARBONIC ANHYDRASE I FROM THE RHESUS MACAQUE1 (2003) (0)
Localization of the mitochondrial carbonic anhydrase V gene, Car5, on mouse chromosome 8 (1997) (0)
Inherited variations in aromatic metabolism. (1960) (0)
Bird communities of Indian River marsh. (1948) (0)
Referees for Volume 41 (2004) (0)
Genetic implications of certain physiological processes affecting the metabolism of L-phenylalanine in man. (1957) (0)
Evidence for multiple carbonic anhydrase II genes in the mouse (1984) (0)
Subject Index Vol. 44, 1987 (1987) (0)
Evolutionary perspectives and the new genetics: (Final report) (1986) (0)
Isolation and structure of huyman carbonic anhydrase II cDNA (1987) (0)
On Brace's Notion of "Hominid Catastrophism" (1973) (0)
Nesting study of the Ruby-throated Hummingbird. (1948) (0)
Hydrogen-tritium exchange in human erythrocyte carbonic anhydrases B and C. (1970) (0)
Amino acid substitution and chemical characterization of a Japanese variant of carbonic anhydrase I: CA I Hiroshima-1 (86 Asp replaced by Gly). (1981) (0)
Carbonic Anhydrase-Related Protein XI: Structure of the Gene in the Greater False Vampire Bat (Megaderma lyra) Compared with Human and Domestic Pig (2013) (0)
Letter to the Editor: ITALIAN OFFICIAL STATISTICS ON CONSANGUINEOUS MARRIAGES (1959) (0)
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS SUBSTITUTION OF LYSINE FOR THREONINE AT POSITION 100 IN HUMAN CARBONIC (2003) (0)
A colleague's personal account of J.V. Neel's early incorporation of isozymes and isoforms into his research on the causes and consequences of mutations. (2003) (0)

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