Richard Henry Baltz
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Biology
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Computational Biology
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Microbiology
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Biology
Richard Henry Baltz's Degrees
- Bachelors Biology Stanford University
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(Suggest an Edit or Addition)Richard Henry Baltz's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Genome of the Bacterium Streptococcus pneumoniae Strain R6 (2001) (772)
- Natural product discovery: past, present, and future (2016) (614)
- Renaissance in antibacterial discovery from actinomycetes. (2008) (465)
- The biochemistry of mutagenesis. (1976) (325)
- Daptomycin biosynthesis in Streptomyces roseosporus: cloning and analysis of the gene cluster and revision of peptide stereochemistry. (2005) (311)
- Natural products to drugs: daptomycin and related lipopeptide antibiotics. (2005) (274)
- Marcel Faber Roundtable: Is our antibiotic pipeline unproductive because of starvation, constipation or lack of inspiration? (2006) (251)
- Daptomycin: mechanisms of action and resistance, and biosynthetic engineering. (2009) (240)
- Combinatorial biosynthesis of novel antibiotics related to daptomycin (2006) (236)
- Microbial genome mining for accelerated natural products discovery: is a renaissance in the making? (2014) (210)
- Streptomyces and Saccharopolyspora hosts for heterologous expression of secondary metabolite gene clusters (2010) (205)
- Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa. (2001) (176)
- Gifted microbes for genome mining and natural product discovery (2017) (170)
- Genetic recombination in Streptomyces fradiae by protoplast fusion and cell regeneration. (1978) (156)
- Production of hybrid glycopeptide antibiotics in vitro and in Streptomyces toyocaensis. (1997) (154)
- Industrial Microorganisms: Basic and Applied Molecular Genetics (1993) (151)
- Genetic manipulation of antibiotic-producing Streptomyces. (1998) (143)
- Molecular engineering approaches to peptide, polyketide and other antibiotics (2006) (140)
- Genetics of Industrial Microorganisms (1979) (129)
- Genetic manipulation of secondary metabolite biosynthesis for improved production in Streptomyces and other actinomycetes (2016) (128)
- Daptomycin: from the mountain to the clinic, with essential help from Francis Tally, MD. (2010) (124)
- Cloning and Expression in Streptomyces lividans of Clustered Erythromycin Biosynthesis Genes from Streptomyces erythreus (1986) (119)
- Combinatorial biosynthesis of cyclic lipopeptide antibiotics: a model for synthetic biology to accelerate the evolution of secondary metabolite biosynthetic pathways. (2014) (106)
- Genetic engineering in Streptomyces roseosporus to produce hybrid lipopeptide antibiotics. (2006) (101)
- Strain improvement in actinomycetes in the postgenomic era (2011) (92)
- Genetically Engineered Lipopeptide Antibiotics Related to A54145 and Daptomycin with Improved Properties (2010) (92)
- Protoplast fusion in Streptomyces: conditions for efficient genetic recombination and cell regeneration. (1981) (90)
- Heterologous production of daptomycin in Streptomyces lividans (2006) (88)
- Genetics of Streptomyces Fradiae and Tylosin Biosynthesis (1988) (88)
- Conjugal transfer of cosmid DNA from Escherichia coli to Saccharopolyspora spinosa: effects of chromosomal insertions on macrolide A83543 production. (1994) (87)
- Natural product drug discovery in the genomic era: realities, conjectures, misconceptions, and opportunities (2019) (86)
- Antimicrobials from Actinomycetes: Back to the Future (2018) (85)
- The lipopeptide antibiotic A54145 biosynthetic gene cluster from Streptomyces fradiae (2006) (84)
- Function of MbtH homologs in nonribosomal peptide biosynthesis and applications in secondary metabolite discovery (2011) (84)
- Non-ribosomal peptide synthetase module fusions to produce derivatives of daptomycin in Streptomyces roseosporus. (2008) (81)
- Heat mutagenesis in bacteriophage T4: the transition pathway. (1976) (80)
- Efficient plasmid transformation of Streptomyces ambofaciens and Streptomyces fradiae protoplasts (1985) (74)
- Restriction of bacteriophage plaque formation in Streptomyces spp (1984) (70)
- A glutamic acid 3‐methyltransferase encoded by an accessory gene locus important for daptomycin biosynthesis in Streptomyces roseosporus (2006) (67)
- Biosynthesis of the macrolide antibiotic tylosin. A preferred pathway from tylactone to tylosin. (1983) (67)
- Transposition of Tn5096 and other IS493 derivatives in Streptomyces griseofuscus (1991) (64)
- Streptomyces temperate bacteriophage integration systems for stable genetic engineering of actinomycetes (and other organisms) (2012) (63)
- Combinatorial biosynthesis of lipopeptide antibiotics in Streptomyces roseosporus (2006) (61)
- Molecular Cloning and Physical Mapping of the Daptomycin Gene Cluster from Streptomyces roseosporus (1998) (60)
- Development of a Genetic System for Combinatorial Biosynthesis of Lipopeptides in Streptomyces fradiae and Heterologous Expression of the A54145 Biosynthesis Gene Cluster (2010) (59)
- Complementation of daptomycin dptA and dptD deletion mutations in trans and production of hybrid lipopeptide antibiotics. (2006) (58)
- Biosynthesis and genetic engineering of lipopeptide antibiotics related to daptomycin. (2008) (55)
- Genetic methods and strategies for secondary metabolite yield improvement in actinomycetes (2001) (54)
- Use of rpsL for dominance selection and gene replacement in Streptomyces roseosporus (1997) (53)
- Mutagenic DNA repair in Streptomyces. (1985) (52)
- Efficient transformation of Amycolatopsis orientalis (Nocardia orientalis) protoplasts by Streptomyces plasmids (1987) (50)
- Properties of S-adenosyl-L-methionine:macrocin O-methyltransferase in extracts of Streptomyces fradiae strains which produce normal or elevated levels of tylosin and in mutants blocked in specific O-methylations (1981) (49)
- Genetic recombination by protoplast fusion in Streptomyces, (Volume 21) (1999) (49)
- Natural Products to Drugs: Daptomycin and Related Lipopeptide Antibiotics (2006) (48)
- Synthetic biology advances and applications in the biotechnology industry: a perspective (2018) (46)
- Transduction of plasmid DNA in Streptomyces spp. and related genera by bacteriophage FP43 (1988) (45)
- A cluster of genes for the biosynthesis of spinosyns, novel macrolide insect control agents produced by Saccharopolyspora spinosa (2000) (43)
- Genetics of Streptomyces fradiae and tylosin biosynthesis. (1988) (42)
- Synthetic biology, genome mining, and combinatorial biosynthesis of NRPS-derived antibiotics: a perspective (2018) (42)
- S-Adenosyl-L-methionine: macrocin O-methyltransferase activities in a series of Streptomyces fradiae mutants that produce different levels of the macrolide antibiotic tylosin (1982) (42)
- A gene cloning system for 'Streptomyces toyocaensis'. (1996) (41)
- Genes for the biosynthesis of spinosyns: applications for yield improvement in Saccharopolyspora spinosa (2001) (41)
- Structure-activity studies among 16-membered macrolide antibiotics related to tylosin. (1982) (37)
- Gene transfer and transposition mutagenesis in Streptomyces roseosporus: mapping of insertions that influence daptomycin or pigment production. (1996) (37)
- Production of novel lipopeptide antibiotics related to A54145 by Streptomyces fradiae mutants blocked in biosynthesis of modified amino acids and assignment of lptJ, lptK and lptL gene functions (2011) (36)
- Tn5099, a xylE promoter probe transposon for Streptomyces spp (1991) (34)
- Genomics and the ancient origins of the daptomycin biosynthetic gene cluster (2010) (34)
- Molecular genetic methods for improving secondary-metabolite production in actinomycetes. (1996) (34)
- Formation of desacetylcephalosporin C in cephalosporin C fermentation. (1968) (34)
- Manual of Industrial Microbiology and Biotechnology, Third Edition (2010) (32)
- Structural characterization of daptomycin analogues A21978C1-3(d-Asn11) produced by a recombinant Streptomyces roseosporus strain. (2007) (31)
- DNA sequence sampling of the Streptococcus pneumoniae genome to identify novel targets for antibiotic development. (1998) (27)
- Transformation of Saccharopolyspora spinosa protoplasts with plasmid DNA modified in vitro to avoid host restriction (1994) (26)
- Hypertransposing derivatives of the streptomycete insertion sequence IS493. (1994) (24)
- Elucidation of structure of novel macrolide antibiotics produced by mutant strains of Streptomyces fradiae. (1983) (24)
- Molecular beacons to identify gifted microbes for genome mining (2017) (23)
- Phenotypic changes associated with loss of expression of tylosin biosynthesis and resistance genes in Streptomyces fradiae. (1985) (23)
- Applications of transposition mutagenesis in antibiotic producing streptomycetes (1997) (22)
- Transposition mutagenesis in Streptomyces fradiae: identification of a neutral site for the stable insertion of DNA by transposon exchange. (1996) (22)
- New genetic methods to improve secondary metabolite production in Streptomyces (1998) (22)
- Genetic transformation of Micromonospora rosaria by the Streptomyces plasmid pIJ702. (1988) (22)
- MbtH homology codes to identify gifted microbes for genome mining (2014) (22)
- Transposition of Tn5096 from a temperature-sensitive transducible plasmid in Streptomyces spp (1991) (20)
- Chapter 20. Biosynthesis and genetic engineering of lipopeptides in Streptomyces roseosporus. (2009) (19)
- Genetics and biochemistry on tylosin production: a model for genetic engineering in antibiotic-producing Streptomyces. (1982) (19)
- Spontaneous and induced mutations to rifampicin, streptomycin and spectinomycin resistances in actinomycetes: mutagenic mechanisms and applications for strain improvement (2014) (18)
- Transposition of Tn5096 and related transposons in Streptomyces species. (1992) (18)
- Transduction and transformation of plasmid DNA in Streptomyces fradiae strains that express different levels of restriction (1989) (17)
- LIPOPEPTIDE ANTIBIOTICS PRODUCED BY STREPTOMYCES ROSEOSPORUS AND STREPTOMYCES FRADIAE (1997) (16)
- Genome mining for drug discovery: progress at the front end (2021) (16)
- Gene expression using streptomycetes. (1990) (16)
- MOLECULAR GENETIC APPROACHES TO YIELD IMPROVEMENT IN ACTINOMYCETES (1997) (16)
- Properties of the streptomycete temperate bacteriophage FP43 (1991) (16)
- Adaptive response and enhancement of N-methyl-N'-nitro-N-nitrosoguanidine mutagenesis by chloramphenicol in Streptomyces fradiae (1985) (15)
- recA gene of Escherichia coli complements defects in DNA repair and mutagenesis in Streptomyces fradiae JS6 (mcr-6) (1987) (15)
- Heat mutagenesis in bacteriophage T4: the transversion pathway. (1976) (14)
- Bacteriophage-resistant industrial fermentation strains: from the cradle to CRISPR/Cas9 (2018) (14)
- Mutants of Streptomyces roseosporus that express enhanced recombination within partially homologous genes. (1996) (14)
- Advances in protoplast fusion and transformation in Streptomyces. (1983) (13)
- Novel fermentation products from Streptomyces fradiae: X-ray crystal structure of 5-O-mycarosyltylactone and proof of the absolute configuration of tylosin. (1982) (13)
- Structural characterization of a lipopeptide antibiotic A54145E(Asn3Asp9) produced by a genetically engineered strain of Streptomyces fradiae (2011) (13)
- Streptomyces lipmanii expresses two restriction systems that inhibit plasmid transformation and bacteriophage plaque formation (1989) (13)
- Characterization of FP22, a large streptomycete bacteriophage with DNA insensitive to cleavage by many restriction enzymes. (1990) (13)
- Transduction of plasmid DNA in macrolide producing streptomycetes. (1989) (12)
- Highly transformable mutants of Streptomyces fradiae defective in several restriction systems (1987) (12)
- Infectious DNA of bacteriophage T4. (1971) (11)
- Gene expression in recombinant Streptomyces. (1995) (11)
- Combinatorial glycosylation of glycopeptide antibiotics. (2002) (11)
- Bacteriophage T4 transformation: an assay for mutations induced in vitro. (1972) (11)
- Efficient Transformation ofAmycolatopsis orientalis (Nocardia orientalis) Protoplasts byStreptomyces Plasmids (1987) (10)
- High frequency conjugal transfer of tylosin genes and amplifiable DNA in Streptomyces fradiae (1986) (10)
- Mutagenic and error-free DNA repair in Streptomyces (2004) (9)
- 23 – Production of Novel Antibiotics by Gene Cloning and Protein Engineering (1973) (7)
- Genome mining for drug discovery: cyclic lipopeptides related to daptomycin (2021) (7)
- DNA homology between Saccharopolyspora strains and other erythromycin-producing actinomycetes (1990) (7)
- Microbial Genome Mining for Natural Product Drug Discovery (2017) (7)
- Genetic Engineering of Acidic Lipopeptide Antibiotics (2010) (5)
- Structural Organization and Regulation of Antibiotic Biosynthesis and Resistance Genes in Actinomycetes (2020) (5)
- Transduction of plasmid DNA containing the ermE gene and expression of erythromycin-resistance in streptomycetes. (1991) (5)
- Spectinomycin Resistance in rpsE Mutants is Recessive in Streptomyces roseosporus (2005) (5)
- Antimicrobials from Actinomycetes : Back to the Future Actinomycetes are the source of most clinically relevant antibiotics in use today and may continue to (2007) (3)
- Transposition and transduction of plasmid DNA inStreptomyces spp. (1991) (3)
- Introduction to the Special Issue: “Natural Product Discovery and Development in the Genomic Era” (2016) (3)
- Heat mutagenesis in bacteriophage T 4 : The transition pathway ( spontaneous mutation / acid mutagenesis / cytosine deamination / evolution rates ) (3)
- Genetic Engineering Solutions for Natural Products in Actinomycetes (2003) (3)
- Daptomycin and A54145: Structure–Activity Relationship (SAR) Studies Enabled by Combinatorial Biosynthesis (2014) (3)
- Highlights of the Annual Meeting of SIM, 2005 (2006) (3)
- Reprogramming Daptomycin and A54145 Biosynthesis to Produce Novel Lipopeptide Antibiotics (2011) (3)
- Heat mutagenesis in bacteriophage T 4 : The transversion pathway ( spontaneous mutation / acid mutagenesis / glycosidic bond migration (2003) (2)
- Biological properties of an improved transformation assay for native and denatured T4 DNA. (1976) (2)
- Transfection and Transformation With Bacteriophage-T4 Dna (1971) (1)
- Formation ofDesacetylcephalosporin Cin Cephalosporin CFermentation (1968) (1)
- Correction to: Synthetic biology, genome mining, and combinatorial biosynthesis of NRPS‑derived antibiotics: a perspective (2018) (1)
- Introduction to the special issue: “Natural Product Discovery and Development in the Genomic Era: 2021” (2021) (1)
- Introduction to the special issue: “Natural Product Discovery and Development in the Genomic Era: 2019” (2019) (1)
- Introduction to the Special Issue: “Arnold Demain—Industrial Microbiologist Extraordinaire” (2017) (1)
- Purification and partial characterization of a proteolytic enzyme from Cephalosporium acremonium (Corda) (1971) (1)
- Sweet home actinomycetes: The 1999 MDS Panlabs Lecture (2000) (1)
- Daptomycin and Related Lipopeptides Produced by Fermentation, Chemical Modification, and Combinatorial Biosynthesis (2014) (1)
- Chapter 14:Daptomycin (2009) (0)
- Dedication to Professor Julian Davies (2006) (0)
- Proceedings from the Genetics and Molecular Biology of Insustrial Microorganisms (GMBIM) conference (1997) (0)
- Tn5O99, a xylEPromoter ProbeTransposon forStreptomyces spp. (1991) (0)
- 2018 Ad hoc reviewers (2019) (0)
- United States Patent ( 19 ) Politino et al . USOO 5869309 A 11 Patent Number : 5 , 869 , 309 ( 45 ) Date of Patent : Feb . 9 , 1999 54 CEPHALOSPORIN ESTERASE GENE FROM (2017) (0)
- Properties ofS-Adenosyl-L-Methionine:Macrocin 0- Methyltransferase inExtracts ofStreptomyces fradiae Strains WhichProduce Normal orElevated Levels ofTylosin andin Mutants Blocked inSpecific 0-Methylations (1981) (0)
- Introduction to Special Issue on "Frontiers in Industrial Microbiology and Biotechnology 2020". (2020) (0)
- DNA segment which induces high-frequency transduction of recombinant-RNA vectors (1988) (0)
- biosynthetic genes for the production of spinosyn insecticides. (1999) (0)
- Introduction to the Special Issue on "Recent Advances in Fermentation Technology 2020". (2020) (0)
- A method for identifying and isolating antibiotic biosynthetic genes (1986) (0)
- Elevated Levels of Tylosin and in Mutants Blocked in Specific 0-Methylations (0)
- Tn 5 O 99 , a xylE Promoter Probe Transposon for Streptomyces spp (0)
- Introduction to Special Issue on “Frontiers in Industrial Microbiology and Biotechnology 2019” (2019) (0)
- Biosynthetic genes for spinosyn insecticide-manufacturing (1999) (0)
- Transduction ofPlasmid DNA inStreptomyces spp.andRelated GenerabyBacteriophage FP43 (1988) (0)
- DNA segment that confers high frequency transducing recombinant DNA vectors. (1988) (0)
- A method for isolating genes for the biosynthesis of antibiotics. (1986) (0)
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