Robert H. Roth

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Robert H. Roth is affiliated with the following schools: Yale University, Rush University

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Robert H. Roth

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Neuroscience

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#259

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Robert H. Roth's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Topographical organization of the efferent projections of the medial prefrontal cortex in the rat: An anterograde tract‐tracing study with Phaseolus vulgaris leucoagglutinin (1989) (1613)
The Biochemical Basis of Neuropharmacology (1975) (1516)
Dopaminergic neurons: effect of antipsychotic drugs and amphetamine on single cell activity. (1973) (1288)
The Neuropsychopharmacology of Phencyclidine: From NMDA Receptor Hypofunction to the Dopamine Hypothesis of Schizophrenia (1999) (1286)
Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite. (2006) (859)
Increased dopamine turnover in the prefrontal cortex impairs spatial working memory performance in rats and monkeys. (1996) (609)
Unilateral transplantation of human fetal mesencephalic tissue into the caudate nucleus of patients with Parkinson's disease. (1992) (512)
Pharmacology of mesocortical dopamine neurons. (1983) (496)
Comparison of effects of L-dopa, amphetamine and apomorphine on firing rate of rat dopaminergic neurones. (1973) (451)
CHOLINE: SELECTIVE ACCUMULATION BY CENTRAL CHOLINERGIC NEURONS (1973) (421)
Enduring cognitive deficits and cortical dopamine dysfunction in monkeys after long-term administration of phencyclidine. (1997) (411)
The determinants of stress-induced activation of the prefrontal cortical dopamine system. (1990) (396)
Role of the Amygdala in the Coordination of Behavioral, Neuroendocrine, and Prefrontal Cortical Monoamine Responses to Psychological Stress in the Rat (1996) (381)
Central dopaminergic neurons: effects of alterations in impulse flow on the accumulation of dihydroxyphenylacetic acid. (1976) (366)
SPECT imaging of dopamine and serotonin transporters with [123I]β‐CIT: Pharmacological characterization of brain uptake in nonhuman primates (1993) (363)
Stress and the Mesocorticolimbic Dopamine Systems a (1988) (358)
Footshock and conditioned stress increase 3, 4-dihydroxyphenylacetic acid (DOPAC) in the ventral tegmental area but not substantia nigra (1985) (357)
Behavioral improvement in a primate Parkinson's model is associated with multiple homeostatic effects of human neural stem cells (2007) (354)
Prefrontal cortical dopamine depletion enhances the responsiveness of mesolimbic dopamine neurons to stress (1990) (334)
Subchronic Phencyclidine Administration Reduces Mesoprefrontal Dopamine Utilization and Impairs Prefrontal Cortical-Dependent Cognition in the Rat (1997) (328)
Increased turnover of norepinephrine in the rat cerebral cortex during stress: role of the locus coeruleus. (1973) (317)
Evidence for the absence of impulse-regulating somatodendritic and synthesis-modulating nerve terminal autoreceptors on subpopulations of mesocortical dopamine neurons (1984) (312)
Dialytrode for long term intracerebral perfusion in awake monkeys. (1972) (287)
Dopamine Synthesis, Uptake, Metabolism, and Receptors: Relevance to Gene Therapy of Parkinson's Disease (1997) (281)
MicroRNA-132 dysregulation in schizophrenia has implications for both neurodevelopment and adult brain function (2012) (274)
The biochemical basis of neuropharmacology, 8th ed. (2003) (274)
Estrogen Is Essential for Maintaining Nigrostriatal Dopamine Neurons in Primates: Implications for Parkinson's Disease and Memory (2000) (259)
GABA levels in CSF of patients with psychiatric disorders. (1980) (255)
Stimulation and destruction of the locus coeruleus: opposite effects on 3-methoxy-4-hydroxyphenylglycol sulfate levels in the rat cerebral cortex. (1973) (249)
Ghrelin Promotes and Protects Nigrostriatal Dopamine Function via a UCP2-Dependent Mitochondrial Mechanism (2009) (248)
Cocaethylene: a neuropharmacologically active metabolite associated with concurrent cocaine-ethanol ingestion. (1991) (248)
FETAL NEURONAL GRAFTS IN MONKEYS GIVEN METHYLPHENYLTETRAHYDROPYRIDINE (1986) (243)
Dopamine and Spatial Working Memory in Rats and Monkeys: Pharmacological Reversal of Stress-Induced Impairment (1996) (237)
Tryptophan hydroxylase activity and synaptosomal uptake of serotonin in discrete brain regions after midbrain raphe lesions: correlations with serotonin levels and histochemical fluorescence. (1972) (235)
Dopaminergic neurons: similar biochemical and histochemical effects of gamma-hydroxybutyrate and acute lesions of the nigro-neostriatal pathway. (1973) (218)
Tricyclic antidepressants: effects on the firing rate of brain noradrenergic neurons. (1975) (215)
Dopaminergic neurons: drug-induced antagonism of the increase in tyrosine hydroxylase activity produced by cessation of impulse flow. (1974) (212)
Evidence that angiotensin enhances transmitter release during sympathetic nerve stimulation (1971) (207)
The biochemical basis of neuropharmacology, 2nd ed. (1974) (206)
Effect of impulse flow on the release and synthesis of dopamine in the striatum (1973) (205)
3,4-Dihydroxyphenylacetic acid and homovanillic acid in rat plasma: possible indicators of central dopaminergic activity. (1979) (205)
Telencephalic Projections of the A8 Dopamine Cell Group (1988) (204)
Serotonin-containing neuronal perikarya and terminals: differential effects of P-chlorophenylalanine. (1973) (202)
Cocaine increases extracellular dopamine in rat nucleus accumbens and ventral tegmental area as shown by in vivo microdialysis (1989) (198)
The role of mesoprefrontal dopamine neurons in the acquisition and expression of conditioned fear in the rat (1999) (194)
Mesocortical dopamine neurons. Lack of autoreceptors modulating dopamine synthesis. (1981) (194)
Uncoupling Protein-2 Is Critical for Nigral Dopamine Cell Survival in a Mouse Model of Parkinson's Disease (2005) (189)
CNS Dopamine Autoreceptors: Distribution, Pharmacology, and Function a (1984) (187)
Synaptosomes from forebrains of rats with midbrain raphe lesions: selective reduction of serotonin uptake. (1972) (186)
The predator odor, TMT, displays a unique, stress-like pattern of dopaminergic and endocrinological activation in the rat (2000) (181)
Natural occurrence of gamma-hydroxybutyrate in mammalian brain (1970) (178)
Effect of gamma-hydroxybutyrate on dopamine and dopamine metabolites in the rat striatum. (1972) (167)
Autoreceptor Regulation of Dopamine Synthesis (1990) (164)
Amphetamine‐stimulated dopamine release competes in vivo for [123I]IBZM binding to the D2 receptor in nonhuman primates (1992) (164)
Subchronic Phencyclidine Administration Increases Mesolimbic Dopaminergic System Responsivity and Augments Stress- and Psychostimulant-Induced Hyperlocomotion (1998) (162)
Δ9-Tetrahydrocannabinol Increases Prefrontal Cortical Catecholaminergic Utilization and Impairs Spatial Working Memory in the Rat: Blockade of Dopaminergic Effects with HA966 (1997) (161)
Identification of endogenous gamma-hydroxybutyrate in human and bovine brain and its regional distribution in human, guinea pig and rhesus monkey brain. (1978) (153)
Evidence for involvement of protein kinase in the activation by adenosine 3':5'-monophosphate of brain tyrosine 3-monooxygenase. (1975) (153)
5-HT2 Receptor Regulation of Extracellular GABA Levels in the Prefrontal Cortex (1999) (152)
Selective reduction of tryptophan hydroxylase activity in rat forebrain after midbrain raphe lesions. (1971) (148)
Regulation of dopamine synthesis in the medial prefrontal cortex is mediated by release modulating autoreceptors: studies in vivo. (1986) (146)
Mesolimbic and mesocortical dopamine activation induced by phencyclidine: contrasting pattern to striatal response. (1987) (145)
Regulation of catecholamine synthesis in the rat brain in vitro by cyclic AMP (1974) (144)
Effect ofl-glutamate on the release of striatal dopamine: in vivo dialysis and electrochemical studies (1990) (144)
Dihydrexidine, a full dopamine D1 agonist, reduces MPTP-induced parkinsonism in monkeys. (1991) (141)
Cognitive and motor deficits in the acquisition of an object retrieval/detour task in MPTP-treated monkeys. (1990) (136)
Mesocortical dopamine neurons: rapid transmitter turnover compared to other brain catecholamine systems. (1981) (135)
Presynaptic adrenergic receptor sensitivity in depression. The effect of long-term desipramine treatment. (1981) (134)
Noradrenergic modulation of serotonin synthesis and metabolism. I. Inhibition by clonidine in vivo. (1982) (130)
Conversion in vivo of γ-aminobutyric to γ-hydroxybutyric acid in the rat (1969) (128)
Symptomatic and asymptomatic 1 -methyl-4-phenyl-1,2,3,6-tetrahydropyridinetreated primates: Biochemical changes in striatal regions (1989) (127)
The determination of a brain arteriovenous difference for 3-methoxy-4-hydroxyphenethyleneglycol (MHPG) (1976) (127)
The role of mesoprefrontal dopamine neurons in stress. (1996) (126)
Panic-Induced Elevation of Plasma MHPG Levels in Phobic-Anxious Patients: Effects of Clonidine and Imipramine (1983) (122)
Dopaminergic neurons: Role of presynaptic receptors in the regulation of transmitter biosynthesis (1978) (122)
Engagement in a non‐escape (displacement) behavior elicits a selective and lateralized suppression of frontal cortical dopaminergic utilization in stress (1999) (121)
D1 and D2 dopamine receptors independently regulate spontaneous blink rate in the vervet monkey. (1991) (120)
Plasma and cerebrospinal fluid 3-methoxy-4-hydroxyphenylethylene glycol (MHPG) as indices of brain norepinephrine metabolism in primates (1982) (119)
TMT, a predator odor, elevates mesoprefrontal dopamine metabolic activity and disrupts short-term working memory in the rat (2000) (119)
Regulation of excitatory amino acid release by N-methyl-d-aspartate receptors in rat striatum: in vivo microdialysis studies (1992) (117)
Mechanism of the gamma-hydroxybutyrate-induced increase in brain dopamine and its relationship to "sleep". (1970) (117)
Dopaminergic neurons: An in vivo system for measuring drug interactions with presynaptic receptors (1976) (117)
Survival and growth of fetal catecholamine neurons transplanted into primate brain (1986) (117)
Comparative transduction efficiency of AAV vector serotypes 1-6 in the substantia nigra and striatum of the primate brain. (2010) (116)
Striatal dopaminergic correlates of stable parkinsonism and degree of recovery in old-world primates one year after MPTP treatment (1999) (114)
Coenzyme Q induces nigral mitochondrial uncoupling and prevents dopamine cell loss in a primate model of Parkinson's disease. (2003) (114)
Prenatal exposure to bisphenol A impacts midbrain dopamine neurons and hippocampal spine synapses in non-human primates. (2013) (113)
γ-Butyrolactone and γ-hydroxybutyric acid—I: Distribution and metabolism☆ (1966) (113)
An Antisense Oligonucleotide Reverses the Footshock-Induced Expression of Fos in the Rat Medial Prefrontal Cortex and the Subsequent Expression of Conditioned Fear-Induced Immobility (1999) (113)
Nicotine Receptor Inactivation Decreases Sensitivity to Cocaine (2001) (111)
Clonidine reversal of increased norepinephrine metabolite levels during morphine withdrawal. (1979) (110)
Denervation supersensitivity to serotonin in rat forebrain: Single cell studies (1979) (108)
In the Blink of an Eye: Relating Positive-Feedback Sensitivity to Striatal Dopamine D2-Like Receptors through Blink Rate (2014) (108)
Unique response to antipsychotic drugs is due to absence of terminal autoreceptors in mesocortical dopamine neurones (1982) (106)
Advances in Cytopharmacology (1973) (103)
Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on catecholamines and metabolites in primate brain and CSF (1987) (103)
Stress-induced activation of prefrontal cortex dopamine turnover: blockade by lesions of the amygdala (1994) (103)
Cryopreservation, culture, and transplantation of human fetal mesencephalic tissue into monkeys. (1988) (102)
Selective increase in dopamine metabolism in the prefrontal cortex by the anxiogenic beta-carboline FG 7142. (1985) (102)
Antipsychotic drug action in schizophrenic patients: effect on cortical dopamine metabolism after long-term treatment. (1979) (100)
Prefrontal cortical involvement in phencyclidine-induced activation of the mesolimbic dopamine system: behavioral and neurochemical evidence (1998) (99)
Stimulation by dopamine of adenosine cyclic 3',5'-monophosphate formation in rat caudate nucleus: effect of lesions of the nigro-neostriatal pathway. (1976) (98)
Role for dopamine in the behavioral functions of the prefrontal corticostriatal system: implications for mental disorders and psychotropic drug action. (2000) (97)
Pharmacology of dopamine neurons innervating the prefrontal, cingulate and piriform cortices. (1983) (97)
Immunohistochemical localization of a neuronal nicotinic acetylcholine receptor in mammalian brain. (1987) (96)
Improvements in MPTP-induced object retrieval deficits and behavioral deficits after fetal nigral grafting in monkeys. (1990) (96)
Dopamine neurons: role of impulse flow and presynaptic receptors in the regulation of tyrosine hydroxylase. (1975) (95)
Dopaminergic neurons--alteration in the kinetic properties of tyrosine hydroxylase after cessation of impulse flow. (1976) (95)
Differential Estimation of Gamma-butyrolactone and Gamma-hydroxybutyric Acid in Rat Blood and Brain (1964) (93)
Altered frontal cortical dopaminergic transmission in monkeys after subchronic phencyclidine exposure: involvement in frontostriatal cognitive deficits (1999) (93)
The Anxiogenic β‐Carboline FG 7142 Selectively Increases Dopamine Release in Rat Prefrontal Cortex as Measured by Microdialysis (1991) (93)
KINETICS OF IN VIVO CONVERSION OF γ‐[3H]AMINOBUTYRIC ACID TO γ‐[3H]HYDROXYBUTYRIC ACID BY RAT BRAIN 1, 2 (1977) (92)
Piribedil and apomorphine: pre- and postsynaptic effects on dopamine synthesis and neuronal activity. (1975) (91)
Characterization of dopamine release in the rat medial prefrontal cortex as assessed by in vivo microdialysis: Comparison to the striatum (1990) (90)
Human neural stem cells migrate along the nigrostriatal pathway in a primate model of Parkinson's disease (2008) (88)
Dopaminergic neurons: effects of electrical stimulation on dopamine biosynthesis. (1976) (88)
Brain contribution to the haloperidol-induced increase in plasma homovanillic acid. (1981) (88)
Dopamine D4 receptor antagonist reversal of subchronic phencyclidine-induced object retrieval/detour deficits in monkeys (1999) (88)
Clozapine Preferentially Increases Dopamine Release in the Rhesus Monkey Prefrontal Cortex Compared with the Caudate Nucleus (1999) (87)
Acceleration of noradrenaline biosynthesis by nerve stimulation. (1966) (87)
Gamma-hydroxybutyrate: a role in the regulation of central dopaminergic neurons? (1980) (86)
Individual differences in behavioral measures: Correlations with nucleus accumbens dopamine measured by microdialysis (1991) (86)
γ-butyrolactone and γ-hydroxybutyric acid—II. The pharmacologically active form (1966) (85)
Influence of dopamine agonists on plasma and brain levels of homovanillic acid. (1982) (85)
Plasma homovanillic acid as an index of brain dopamine metabolism: enhancement with debrisoquin. (1983) (84)
Phencyclidine Increases Forebrain Monoamine Metabolism in Rats and Monkeys: Modulation by the Isomers of HA966 (1997) (84)
Severe long-term 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in the vervet monkey (Cercopithecus aethiops sabaeus) (1997) (83)
Persistent and anatomically selective reduction in prefrontal cortical dopamine metabolism after repeated, intermittent cannabinoid administration to rats (2003) (83)
Locus coeruleus stimulation increases noradrenergic metabolite levels in rat spinal cord (1979) (83)
Formation and regional distribution of γ-hydroxybutyric acid in mammalian brain (1970) (82)
Evidence that central nervous system depression by 1,4-butanediol in mediated through a metabolite, gamma-hydroxybutyrate. (1968) (82)
Mesoprefrontal dopaminergic neurons: can tyrosine availability influence their functions? (1997) (80)
5‐HT1a agonist ±‐ 8‐OH‐DPAT modulates basal and stress‐induced changes in medial prefrontal cortical dopamine (1994) (80)
Neural Stem Cells Implanted into MPTP-Treated Monkeys Increase the Size of Endogenous Tyrosine Hydroxylase-Positive Cells Found in the Striatum: A Return to Control Measures (2005) (78)
Tyrosine hydroxylase: activation by nerve stimulation. (1974) (78)
Clonidine reverses the increased norepinephrine turnover during morphine withdrawal in rats (1980) (78)
Fetal dopamine neural grafts: extended reversal of methylphenyltetrahydropyridine-induced parkinsonism in monkeys. (1988) (77)
Dopaminergic neurons: effects of electrical stimulation on tyrosine hydroxylase. (1976) (77)
Alterations in turnover and endogenous levels of norepinephrine in cerebral cortex following electrical stimulation and acute axotomy of cerebral noradrenergic pathways. (1973) (77)
A direct method for studying 3-methoxy-4-hydroxyphenethyleneglycol (MHPG) production by brain in awake animals. (1977) (77)
Biochemical and behavioral recovery in a rodent model of Parkinson's disease following stereotactic implantation of dopamine-containing liposomes (1992) (76)
Substance K and substance P differentially modulate mesolimbic and mesocortical systems (1985) (76)
D & L amphetamine stereoisomers: comparative potencies in affecting the firing of central dopaminergic and noradrenergic neurons. (1975) (75)
Fear‐like biochemical and behavioral responses in rats to the predator odor, TMT, are dependent on the exposure environment (2002) (74)
Gamma-hydroxybutyrate-induced increase in brain dopamine: localization by fluorescence microscopy. (1970) (73)
Repeated exposure to Δ 9-tetrahydrocannabinol reduces prefrontal cortical dopamine metabolism in the rat (1998) (73)
Effects of 6-hydroxydopamine lesions of the prefrontal cortex on tyrosine hydroxylase activity in mesolimbic and nigrostriatal dopamine systems (1992) (73)
Release of monoamines from the striatum and hypothalamus: Effect of γ‐hydroxybutyrate (1972) (72)
3-Methoxy-4-hydroxyphenethyleneglycol increase in plasma after stimulation of the nucleus locus coeruleus (1978) (72)
Differential responsiveness to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity in sub-regions of the primate substantia nigra and striatum. (1987) (72)
Preferential vulnerability of A8 dopamine neurons in the primate to the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (1986) (71)
Introduction to Neuropsychopharmacology (2008) (71)
Repeated phencyclidine in monkeys results in loss of parvalbumin-containing axo-axonic projections in the prefrontal cortex (2007) (70)
Choline and acetylcholine: regional distribution and effect of degeneration of cholinergic nerve terminals in the rat hippocampus. (1973) (69)
Activation of the locus coeruleus induced by selective stimulation of the ventral tegmental area (1986) (68)
Reduced prefrontal cortical dopamine, but not acetylcholine, release in vivo after repeated, intermittent phencyclidine administration to rats (1998) (68)
The action of reserpine on noradrenaline biosynthesis in sympathetic nerve tissue. (1968) (67)
Biochemical and Physiological Function of Thiamine in Nervous Tissue (1963) (66)
Effect of acute ethanol treatment on transmitter synthesis and metabolism in central dopaminergic neurons (1976) (65)
Effects of haloperidol and probenecid on plasma and CSF dopamine metabolites in the rhesus monkey (Macacca mulatta). (1978) (65)
In vivo assessment of basal and drug‐induced dopamine release in cortical and subcortical regions of the anesthetized primate (1993) (65)
Regional sensitivity of primate brain dopaminergic neurons to haloperidol: alterations following chronic treatment (1978) (65)
Subchronic Phencyclidine Treatment Decreases the Number of Dendritic Spine Synapses in the Rat Prefrontal Cortex (2006) (64)
Cognitive and motor deficits in the performance of an object retrieval task with a barrier-detour in monkeys (Cercopithecus aethiops sabaeus) treated with MPTP: long-term performance and effect of transparency of the barrier. (1990) (63)
Mild footshock stress dissociates substance P from substance K and dynorphin from Met- and Leu-enkephalin (1986) (62)
Cholinergic neurons: effect of acute septal lesion on acetylcholine and choline content of rat hippocampus. (1973) (62)
Regulation of dopamine synthesis in the medial prefrontal cortex: studies in brain slices. (1986) (62)
Dopamine neurons projecting to the medial prefrontal cortex possess release-modulating autoreceptors (1987) (62)
Nicotinic modulation of mesoprefrontal dopamine neurons: pharmacologic and neuroanatomic characterization. (2000) (62)
Reduced locomotor responses to cocaine in ghrelin-deficient mice (2011) (61)
Dopaminergic neurons - alteration in the sensitivity of tyrosine hydroxylase to inhibition by endovenous dopamine after cessation of impulse flow. (1976) (61)
Intracerebral grafting and culture of cryopreserved primate dopamine neurons (1987) (61)
Angiotensin accelerates Catecholamine Biosynthesis in Sympathetically Innervated Tissues (1969) (59)
Stress-induced alterations in neurotensin, somatostatin and corticotropin-releasing factor in mesotelencephalic dopamine system regions (1987) (58)
The use of c8-octyl columns for the analysis of catecholamines by ion-pair reversed-phase liquid chromatography with amperometric detection. (1981) (58)
Stress activation of mesocorticolimbic dopamine neurons: effects of a glycine/NMDA receptor antagonist. (1993) (57)
MELATONIN: DEACETYLATION TO 5‐METHOXYTRYPTAMINE BY LIVER BUT NOT BRAIN ARYL ACYLAMIDASE (1979) (57)
Substance K and substance P in the ventral tegmental area (1985) (57)
Comparison of neurotoxicity following repeated administration of l-dopa, d-dopa and dopamine to embryonic mesencephalic dopamine neurons in cultures derived from Fisher 344 and Sprague-Dawley donors. (1997) (57)
Preliminary report on the metabolism of γ-butyrolactone and γ-hydroxybutyric acid (1965) (57)
Metabolism of [1-14C]γ-hydroxybutyric acid by rat brain after intraventricular injection (1975) (57)
Factors influencing the rate of norepinephrine biosynthesis in nerve tissue. (1967) (57)
Noradrenergic neurons: allosteric activation of hippocampal tyrosine hydroxylase by stimulation of the locus coeruleus. (1974) (56)
Behavioral Effects of MPTP Administration in the Vervet Monkey (1994) (56)
Divergent effects of putative anxiolytics on stress‐induced Fos expression in the mesoprefrontal system of the rat (2000) (56)
Naltrexone precipitated opiate withdrawal in methadone addicted human subjects: evidence for noradrenergic hyperactivity. (1984) (56)
Fetal Dopamine Cell Survival after Transplantation Is Dramatically Improved at a Critical Donor Gestational Age in Nonhuman Primates (1993) (55)
Transplantation of fetal dopamine neurons in primate brain reverses MPTP induced parkinsonism. (1987) (55)
Chronic haloperidol or fluphenazine: effects on dopamine metabolism in brain, cerebrospinal fluid and plasma of Cercopithecus aethiops (vervet monkey). (1980) (55)
Object retrieval/detour deficits in monkeys produced by prior subchronic phencyclidine administration: evidence for cognitive impulsivity (2000) (55)
Stimulation‐Induced Release of Coexistent Transmitters in the Prefrontal Cortex: An In Vivo Microdialysis Study of Dopamine and Neurotensin Release (1989) (55)
MDMA (3,4-methylenedioxymethamphetamine) inhibits the firing of dorsal raphe neurons in brain slices via release of serotonin. (1989) (55)
Light and heavy norepinephrine storage particles in the rat heart and in bovine splenic nerve. (1968) (54)
GLUTAMATE DECARBOXYLASE ACTIVITY IN STRIATAL SLICES: CHARACTERIZATION OF THE INCREASE FOLLOWING DEPOLARIZATION 1, 2 (1979) (54)
Electroconvulsive shock raises prostaglandins F in rat cerebral cortex. (1975) (54)
METABOLISM OF γ‐HYDROXY‐[1‐14C] BUTYRATE BY RAT BRAIN: RELATIONSHIP TO THE KREBS CYCLE AND METABOLIC COMPARTMENTATION OF AMINO ACIDS (1978) (54)
Alpha-2 Adrenoceptor Activation Inhibits Phencyclidine-Induced Deficits of Spatial Working Memory in Rats (2005) (54)
Clozapine Reverses the Spatial Working Memory Deficits Induced by FG7142 in Monkeys (1997) (52)
Effects of alterations in impulse flow on transmitter metabolism in central dopaminergic neurons. (1974) (52)
Effects of CNS stimulants on the in vivo release of the colocalized transmitters, dopamine and neurotensin, from rat prefrontal cortex (1992) (52)
Prenatal cocaine exposure disrupts non-spatial, short-term memory in adolescent and adult male rats (2002) (51)
Plasma MHPG in depression: Effects of acute and chronic desipramine treatment (1981) (51)
Impact of methamphetamine on dopamine neurons in primates is dependent on age: implications for development of Parkinson's disease (2011) (50)
Evidence against specificity of electrical stimulation of the nucleus locus coeruleus in activating the sympathetic nervous system in the rat (1980) (49)
Tryptophan hydroxylase: activation in vivo following stimulation of central serotonergic neurons. (1975) (49)
Selective Increase in Dopamine Utilization in the Shell Subdivision of the Nucleus Accumbens by the Benzodiazepine Inverse Agonist FG 7142 (1995) (48)
Mesocortical dopamine neurons: High basal firing frequency predicts tyrosine dependence of dopamine synthesis (2005) (48)
Noradrenaline formation from dopamine in isolated subcellular particles from bovine splenic nerve. (1967) (48)
Preferential activation of dopamine overflow in prefrontal cortex produced by chronic clozapine treatment (1994) (48)
Activation by cyclic 3':5'-adenosine monophosphate of tyrosine hydroxylase in the rat brain. (1975) (48)
Repeated, Intermittent Δ9-Tetrahydrocannabinol Administration to Rats Impairs Acquisition and Performance of a Test of Visuospatial Divided Attention (2004) (47)
Modulation of mesoprefrontal dopamine neurons by central benzodiazepine receptors. I. Pharmacological characterization. (1990) (47)
Activation of Tyrosine Hydroxylase from Central Noradrenergic Neurons by Calcium (1975) (47)
Preexposure to, but Not Cotreatment with, the Neurotensin Antagonist SR 48692 Delays the Development of Cocaine Sensitization (1994) (46)
Dihydroxyphenylacetic acid conjugate: natural occurrence and demonstration of probenecid-induced accumulation in rat striatum, olfactory tubercles and frontal cortex. (1977) (46)
Serotonergic lesions alter cocaine‐induced locomotor behavior and stress‐activation of the mesocorticolimbic dopamine system (1996) (45)
Effect of L-glutamate on the release of striatal dopamine: in vivo dialysis and electrochemical studies. (1990) (45)
Dopamine and neurotensin storage in colocalized and noncolocalized neuronal populations. (1989) (45)
MPTP-induced parkinsonism: relative changes in dopamine concentration in subregions of substantia nigra, ventral tegmental area and retrorubral field of symptomatic and asymptomatic vervet monkeys (1990) (44)
Amphetamine-induced inhibition of tyrosine hydroxylation in homogenates of rat corpus striatum (1975) (44)
Brain catecholamine metabolites and behavior in morphine withdrawal. (1982) (44)
MPTP reduces dopamine and norepinephrine concentrations in the supplementary motor area and cingulate cortex of the primate (1990) (44)
Complex interaction of cocaine with the dopamine uptake carrier. (1990) (44)
Striatal tyrosine hydroxylase: comparison of the activation produced by depolarization and dibutyryl-cAMP. (1979) (44)
Neuroactive metabolises of L‐tryptophan, serotonin and quinolinic acid, in striatal extracellular fluid effect of tryptophan loading (1989) (43)
Acceleration by stress of dopamine synthesis and metabolism in prefrontal cortex: Antagonism by diazepam (1982) (43)
Biochemical evidence for simultaneous activation of multiple locus coeruleus efferents. (1980) (43)
Conversion of 1,4-butanediol to -hydroxybutyric acid in rat brain and in peripheral tissue. (1972) (42)
Action of angiotensin on adrenergic nerve endings: enhancement of norepinephrine biosynthesis. (1972) (42)
Embryonic ventral mesencephalic grafts to the substantia nigra of MPTP‐treated monkeys: Feasibility relevant to multiple‐target grafting as a therapy for Parkinson's disease (2002) (42)
Differential effects of short and long term lithium on tryptophan uptake and serotonergic function in cat brain. (1981) (41)
Circadian rhythms in catecholamine metabolites and cyclic nucleotide production. (1986) (41)
Synthesis of catecholamines in the locus coeruleus from 3 H-tyrosine in vivo. (1972) (40)
Low circulating levels of bisphenol‐A induce cognitive deficits and loss of asymmetric spine synapses in dorsolateral prefrontal cortex and hippocampus of adult male monkeys (2015) (40)
Effects of repeated nicotine pre-treatment on mesoprefrontal dopaminergic and behavioral responses to acute footshock stress 1 Supported by a Lucille P. Markey Physician-Scientist Fellowship Award and a NARSAD Young Investigator Award (to TPG) and USPHS grant MH-14092 (to RHR). 1 (1998) (40)
General cognitive ability following unilateral and bilateral fetal ventral mesencephalic tissue transplantation for treatment of Parkinson's disease. (1995) (39)
Cryopreservation of human brain tissue (1990) (39)
Phencyclidine-induced Loss of Asymmetric Spine Synapses in Rodent Prefrontal Cortex is Reversed by Acute and Chronic Treatment with Olanzapine (2011) (39)
Effects of D2 dopamine receptor antagonists on fos protein expression in the striatal complex and entorhinal cortex of the nonhuman primate (1996) (39)
Intrastriatal kainic acid: acute effects on electrophysiological and biochemical measures of nigrostriatal dopaminergic activity. (1981) (39)
Regulation of the prefrontal cortical dopamine system by the neuroactive steroid 3a,21-dihydroxy-5a-pregnane-20-one (1992) (39)
3-Acetylpyridine-induced degeneration of the nigrostriatal dopamine system: An animal model of olivopontocerebellar atrophy-associated parkinsonism (1989) (38)
Poststimulation catecholamine synthesis and tyrosine hydroxylase activation in central noradrenergic neurons. I. In vivo stimulation of the locus coeruleus. (1980) (38)
Ergot alkaloids: interaction with presynaptic dopamine receptors in the neostriatum and olfactory tubercles. (1980) (38)
Effects of dopamine autoreceptor stimulation on the release of colocalized transmitters: In vivo release of dopamine and neurotensin from rat prefrontal cortex (1990) (38)
Alcohol plus cocaine: the whole is more than the sum of its parts. (1996) (38)
Activation of tyrosine hydroxylase in rat striatal slices by K+-depolarization--effect of ethanol. (1976) (38)
Sham surgery does not ameliorate MPTP-induced behavioral deficits in monkeys. (1995) (37)
Uncoupling protein‐2 promotes nigrostriatal dopamine neuronal function (2006) (36)
Calcitonin gene-related peptide in the ventral tegmental area: Selective modulation of prefrontal cortical dopamine metabolism (1987) (36)
α‐noradrenergic receptor modulation of the phencyclidine‐ and Δ9‐tetrahydrocannabinol‐induced increases in dopamine utilization in rat prefrontal cortex (1998) (36)
The ascending projections of the dopaminergic neurons of the substantia nigra, zona reticulata: a combined retrograde tracer-immunohistochemical study (1986) (35)
Adrenergic hyperactivity of the aganglionic colon. (1973) (35)
Potassium-induced acceleration of catecholamine biosynthesis in brain slices. I. A study of the mechanism of action. (1971) (35)
Effect of anesthetic doses of hydroxybutyrate on subcortical concentrations of homovanillic acid. (1971) (35)
Asenapine effects on cognitive and monoamine dysfunction elicited by subchronic phencyclidine administration (2012) (34)
Clonidine suppression of noradrenergic hyperactivity during morphine withdrawal by clonidine: biochemical studies in rodents and primates. (1982) (34)
Restoration of dopamine transporter density in the striatum of fetal ventral mesencephalon-grafted, but not sham-grafted, MPTP-treated parkinsonian monkeys. (1996) (34)
Grafting of fetal substantia nigra to striatum reverses behavioral deficits induced by MPTP in primates: a comparison with other types of grafts as controls (2004) (34)
Tyrosine Hydroxylase Regulation: Apparent Kinetic Alterations Following Incubation of Brain Slices in a Sodium‐free Medium (1980) (34)
Striatal dopamine autoreceptors uninfluenced by chronic administration of antidepressants. (1982) (34)
Role of impulse flow in the short-term regulation of norepinephrine biosynthesis (1979) (34)
Striatal dopamine and gamma-hydroxybutyrate. (1976) (34)
Dopaminergic neurons: Effects elicited by γ-hydroxybutyrate are reversed by picrotoxin (1977) (34)
A sensitive method for quantitation of γ-hydroxybutyric acid and γ-butyrolactone in brain by electron capture gas chromatography (1975) (33)
Morphological, neurochemical, and behavioral characterizations associated with the combined treatment of diethyldithiocarbamate and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice (1989) (33)
Dependence of rat serum lactonase upon calcium. (1967) (33)
Norepinephrine levels in experimental spinal cord trauma. Part 1: Biochemical study of hemorrhagic necrosis. (1977) (33)
Precipitated diazepam withdrawal elevates noradrenergic metabolism in primate brain. (1985) (32)
Dopaminergic neurons: Effect of acute and chronic morphine administration on single cell activity and transmitter metabolism (2005) (32)
Homovanillic acid concentrations in brain, CSF and plasma as indicators of central dopamine function in primates (2005) (32)
Dopamine agonists stimulate protein carboxylmethylation in striatal synaptosomes. (1982) (31)
Regional distribution of dopamine metabolites in human and primate brain. (1978) (31)
Regulation of Noradrenaline Biosynthesis in Nerve Tissue (1967) (31)
Panic-induced elevation of plasma MHPG levels in phobic-anxious patients. Effects of clonidine and imipramine. (1983) (31)
Early gestational mesencephalon grafts, but not later gestational mesencephalon, cerebellum or sham grafts, increase dopamine in caudate nucleus of MPTP-treated monkeys (1996) (31)
Correlation of cerebrospinal fluid serotonin and altered spinal cord blood flow in experimental trauma. (1980) (30)
Systemic, but not local, administration of cannabinoid CB1 receptor agonists modulate prefrontal cortical acetylcholine efflux in the rat (2003) (30)
The D1 receptor antagonist, SCH 23390, induces signs of parkinsonism in African green monkeys. (1991) (30)
Cocaine-sensitive and -insensitive dopamine uptake in prefrontal cortex, nucleus accumbens and striatum (1993) (30)
Male Rats Exposed to Cocaine in utero Demonstrate Elevated Expression of Fos in the Prefrontal Cortex in Response to Environment (2002) (29)
Upregulation of striatal D2 receptors in the MPTP-treated vervet monkey is reversed by grafts of fetal ventral mesencephalon: an autoradiographic study (1998) (29)
Embryonic Substantia Nigra Grafts Show Directional Outgrowth to Cografted Striatal Grafts and Potential for Pathway Reconstruction in Nonhuman Primate (2008) (29)
Changes in extracellular levels of glutamate and aspartate in rat substantia nigra induced by dopamine receptor ligands: In vivo microdialysis studies (1995) (29)
Prenatal exposure to cocaine is associated with increased number of spine synapses in rat prelimbic cortex (2007) (29)
The anxiogenic β-carboline FG-7142 increases in vivo and in vitro tyrosine hydroxylation in the prefrontal cortex (1989) (29)
Effects of Repeated Nicotine Administration and Footshock Stress on Rat Mesoprefrontal Dopamine Systems: Evidence for Opioid Mechanisms (2000) (28)
Can Graft-Derived Neurotrophic Activity Be Used to Direct Axonal Outgrowth of Grafted Dopamine Neurons for Circuit Reconstruction in Primates? (1993) (28)
R-(+)-HA-966, an antagonist for the glycine/NMDA receptor, prevents locomotor sensitization to repeated cocaine exposures (1995) (28)
Interaction of [3H]GBR 12935 and GBR 12909 with the dopamine uptake complex in nucleus accumbens. (1990) (28)
The effects of perinatal diazepam exposure on stress-induced activation of the mesotelencephalic dopamine system. (1989) (28)
Novel Radioligands for the Dopamine Transporter Demonstrate the Presence of Intrastriatal Nigral Grafts in the MPTP-Treated Monkey: Correlation with Improved Behavioral Function (1994) (28)
Anxiogenic β-carboline FG 7142 produces activation of noradrenergic neurons in specific brain regions of rats (1991) (27)
Neuropharmacology of 3-isobutylmethylxanthine: effects on central noradrenergic systems in vivo. (1983) (27)
Poststimulation catecholamine synthesis and tyrosine hydroxylase activation in central noradrenergic neurons. II. Depolarized hippocampal slices. (1980) (27)
Prenatal cocaine exposure increases mesoprefrontal dopamine neuron responsivity to mild stress (2001) (27)
Dysregulation of mesoprefrontal dopamine neurons induced by acute and repeated phencyclidine administration in the nonhuman primate: implications for schizophrenia. (1998) (27)
Cryopreservation of fetal rat and non-human primate mesencephalic neurons: viability in culture and neural transplantation. (1988) (27)
Perinatal diazepam exposure: Alterations in exploratory behavior and mesolimbic dopamine turnover (1990) (27)
Norepinephrine levels in experimental spinal cord trauma. Part 2: Histopathological study of hemorrhagic necrosis. (1977) (27)
Axo-Axonic Structures in the Medial Prefrontal Cortex of the Rat: Reduction by Prenatal Exposure to Cocaine (2003) (27)
Biochemical and behavioral anxiolytic-like effects of R(+)HA-966 at the level of the ventral tegmental area in rats (1999) (26)
Autoradiographic localization of dopamine D1 and D2 receptors in rat cerebral cortex following unilateral neurotoxic lesions (1992) (26)
Prior exposure to cocaine diminishes behavioral and biochemical responses to aversive conditioning: Reversal by glycine/N-methyl-d-aspartate antagonist co-treatment (1995) (26)
The Electrophysiological and Biochemical Pharmacology of the Mesolimbic and Mesocortical Dopamine Neurons (1987) (26)
Regional high-affinity [3H]choline accumulation in cat forebrain: selective increase in the caudate-putamen after corticosteroid pretreatment. (1979) (26)
Accumulation of 3-methoxy-4-hydroxyphenylglycol-sulfate in rabbit cerebrospinal fluid following probenecid. (1973) (26)
Dopamine Autoreceptor Stimulation Increases Protein Carboxyl Methylation in Striatal Slices (1985) (26)
Comparison of two alpha-noradrenergic agonists (clonidine and guanfacine) on norepinephrine turnover in the cortex of rats during morphine abstinence. (1981) (25)
Clozapine Normalizes Prefrontal Cortex Dopamine Transmission in Monkeys Subchronically Exposed to Phencyclidine (2008) (25)
Efferent synaptic connections of dopaminergic neurons grafted into the caudate nucleus of experimentally induced parkinsonian monkeys are different from those of control animals (1998) (25)
Prenatal exposure to cocaine selectively disrupts the development of parvalbumin containing local circuit neurons in the medial prefrontal cortex of the rat (2005) (24)
The effects of pertussis toxin on autoreceptor-mediated inhibition of dopamine synthesis in the rat striatum. (1988) (24)
Dopamine autoreceptors: pharmacology, function and comparison with post-synaptic dopamine receptors. (1979) (24)
AAV2-mediated gene transfer of GDNF to the striatum of MPTP monkeys enhances the survival and outgrowth of co-implanted fetal dopamine neurons (2008) (24)
Content, synthesis and collectability of amino acids in various structures of the brains of rhesus monkeys. (1970) (24)
Prenatal exposure to cocaine reduces the number and enhances reactivity of A10 dopaminergic neurons to environmental stress (2001) (24)
Regionally-specific alterations in mesotelencephalic dopamine synthesis in diabetic rats: association with precursor tyrosine (2005) (24)
Free and conjugated dihydroxyphenylacetic acid: effect of alterations in impulse flow in rat neostriatum and frontal cortex. (1976) (24)
Cerebrospinal fluid GABA and cyclic nucleotides in alcoholics with and without seizures. (1981) (23)
Apoptotic natural cell death in developing primate dopamine midbrain neurons occurs during a restricted period in the second trimester of gestation (2007) (23)
Gamma-butyrolactone and gamma-hydroxybutyric acid. II. The pharmacologically active form. (1966) (23)
Regionally specific alterations in the low-affinity GABAA receptor following perinatal exposure to diazepam (1990) (23)
Tyrosine Hydroxylase Immunoreactivity and Monoamine and Metabolite Levels in Cryopreserved Human Fetal Ventral Mesencephalon (1993) (23)
3,4-Methylenedioxymethamphetamine-induced release of serotonin and inhibition of dorsal raphe cell firing: potentiation by L-tryptophan. (1990) (23)
K+-dependent stimulation of tyrosine hydroxylation in striatal slices: role of Ca2+/calmodulin and Ca2+/phospholipid-dependent mechanisms. (1986) (23)
Increased Noradrenergic Metabolism in the Cerebellum of the Mouse Mutant Dystonia Musculorum (1982) (23)
Noradrenergic α-2 agonists have anxiolytic-like actions on stress-related behavior and mesoprefrontal dopamine biochemistry (2004) (23)
Effect of gamma-hydroxybutyrate and gamma-butyrolactone on dopamine synthesis and uptake by rat striatum. (1972) (23)
Glutamic acid decarboxylase activity in striatal slices: persistent increase following depolarization. (1978) (22)
GPA protects the nigrostriatal dopamine system by enhancing mitochondrial function (2011) (22)
Presynaptic dopamine receptors. Development of supersensitivity following treatment with fluphenazine decanoate. (1977) (22)
Dopaminergic neurons: activation of tyrosine hydroxylase by a calcium chelator. (1976) (21)
The effect of acute raphe lesion on serotonin synthesis and metabolism in the rat forebrain and hippocampus (1976) (21)
Chronic Imipramine Administration Alters the Activity and Phosphorylation State of Tyrosine Hydroxylase in Dopaminergic Regions of Rat Brain (1995) (21)
Serotonin involvement in cocaine sensitization: Clues from studies with cocaine analogs (1993) (21)
Chronic treatment with haloperidol or fluphenazine decanoate: regional effects on dopamine and serotonin metabolism in primate brain. (1982) (21)
Gamma-hydroxybutyrate treatment of schizophrenia: a pilot study. (1981) (21)
Sub-picogram determination of serotonin using HPLC with electrochemical detection for microdialysis studies of serotonin release. (1991) (20)
Comparison of fetal mesencephalic grafts, AAV-delivered GDNF, and both combined in an MPTP-induced nonhuman primate Parkinson's model. (2013) (20)
Neural Transplantation for Neurodegenerative Diseases: Past, Present, and Future a (1993) (20)
Effect of anesthetic doses of γ-hydroxybutyrate on the acetylcholine content of rat brain (1976) (19)
Abnormal regulation of catecholamine synthesis in pheochromocytoma. (1968) (19)
Cellular repair in the parkinsonian nonhuman primate brain. (2010) (19)
Loss of asymmetric spine synapses in prefrontal cortex of motor-asymptomatic, dopamine-depleted, cognitively impaired MPTP-treated monkeys. (2013) (19)
Monoamine Oxidase Activity in the Bovine Splenic Nerve Granule Preparation (1966) (19)
Effects of molindone on central dopaminergic neuronal activity and metabolism: similarity to other neuroleptics. (1975) (19)
Development of supersensitivity of apomorphine-induced increases in acetylcholine levels and stereotypy after chronic fluphenazine treatment (1978) (19)
Presynaptic dopamine receptors (1977) (19)
(S)-(-)-HA-966, a gamma-hydroxybutyrate-like agent, prevents enhanced mesocorticolimbic dopamine metabolism and behavioral correlates of restraint stress, conditioned fear and cocaine sensitization. (1997) (19)
Cellular replacement of dopamine deficit in Parkinson's disease using human fetal mesencephalic tissue: preliminary results in four patients. (1993) (19)
In vitro microdialysis: a novel technique for stimulated neurotransmitter release measurements (1991) (19)
Clonidine and guanfacine attenuate phencyclidine-induced dopamine overflow in rat prefrontal cortex: Mediating influence of the alpha-2A adrenoceptor subtype (2008) (19)
Spatiotemporal patterns of gene expression during fetal monkey brain development. (2003) (19)
Noradrenergic modulation of serotonin synthesis and metabolism. II. Stimulation by 3-isobutyl-1-methylxanthine. (1983) (19)
Psychiatric status after human fetal mesencephalic tissue transplantation in Parkinson's disease (1995) (18)
D1 Dopamine Receptors of NS20Y Neuroblastoma Cells Are Functionally Similar to Rat Striatal D1 Receptors (1991) (18)
Antipsychotic drugs: differential effects on dopamine neurons in basal ganglia and mesocortex following chronic administration in human and nonhuman primates. (1980) (18)
Tyrosine enhances behavioral and mesocorticolimbic dopaminergic responses to aversive conditioning (1996) (18)
Kinetics of in vivo conversion of gamma-[3H]aminobutyric acid to gamma-[3H]hydroxybutyric acid by rat brain. (1977) (18)
Adaptation of monoaminergic responses to phencyclidine in nucleus accumbens and prefrontal cortex following repeated treatment with fluoxetine or imipramine (2002) (17)
Acceleration of protein synthesis by angiotensin--correlation with angiotensin's effect on catecholamine biosynthesis. (1972) (17)
Adrenergic Denervation of the Hypertrophied Gut Remnant (1972) (17)
The activation of mesoprefrontal dopamine neurons by FG 7142 is absent in rats treated chronically with diazepam. (1987) (17)
Prenatal cocaine exposure enhances responsivity of locus coeruleus norepinephrine neurons: Role of autoreceptors (2007) (17)
Clonidine Prevents Methylxanthine Stimulation of Norepinephrine Metabolism in Rat Brain (1983) (17)
Enhanced release of transmitter during sympathetic nerve stimulation in the presence of angiotensin. (1969) (17)
Loss of asymmetric spine synapses in dorsolateral prefrontal cortex of cognitively impaired phencyclidine-treated monkeys. (2011) (17)
Tyrosine hydroxylase:--examination of conditions influencing activity in pheochromocytoma, adrenal medulla and striatum. (1979) (17)
Intrastriatal grafts from multiple donors do not result in a proportional increase in survival of dopamine neurons in nonhuman primates. (1998) (17)
Survival and Integration of Neurons Derived from Human Embryonic Stem Cells in MPTP-Lesioned Primates (2014) (17)
Yohimbine co-treatment during chronic morphine administration attenuates naloxone-precipitated withdrawal without diminishing tail-flick analgesia in rats (1991) (16)
Primate Phencyclidine Model of Schizophrenia: Sex-Specific Effects on Cognition, Brain Derived Neurotrophic Factor, Spine Synapses, and Dopamine Turnover in Prefrontal Cortex (2015) (16)
Nigrostriatal dopamine neurons: Modulation of impulse-induced activation of tyrosine hydroxylation by dopamine autoreceptors (1987) (16)
Selective activation of the A10, but not A9, dopamine neurons in the rat by the predator odor, 2,5-dihydro-2,4,5-trimethylthiazoline (2002) (16)
Apomorphine-haloperidol interactions: Different types of antagonism in cortical and subcortical brain regions (1981) (16)
Effects of haloperidol administration on in vivo extracellular dopamine in striatum and prefrontal cortex after partial dopamine lesions (1991) (16)
Formation and regional distribution of gamma-hydroxybutyric acid in mammalian brain. (1970) (16)
Pattern of synaptophysin immunoreactivity within mesencephalic grafts following transplantation in a parkinsonian primate model (1998) (16)
Conversion in vivo of gamma-aminobutyric to gamma-hydroxybutyric acid in the rat. (1969) (16)
High‐Affinity [3H]Choline Accumulation in Cultured Human Skin Fibroblasts (1981) (15)
Content and Release of Amino-acids and Catecholamines in Monkey Brain (1969) (15)
Evidence for an irreversible interaction of bromocryptine with central dopamine receptors (1980) (15)
Dopamine Autoreceptor Pharmacology and Function (1997) (14)
Aged monkeys as a partial model for Parkinson's disease (2011) (14)
Tolerance to fluphenazine and supersensitivity to apomorphine in central dopaminergic systems after chronic fluphenazine decanoate treatment (1980) (14)
Regulation of tyrosine hydroxylase from human pheochromocytoma, bovine adrenal and rat striatum. (1978) (14)
Cocaethylene inhibits uptake of dopamine and can reach high plasma concentrations following combined cocaine and ethanol use. (1990) (14)
Low levels of somatostatin-like immunoreactivity in neocortex resected from presumed seizure foci in epileptic patients (1992) (14)
Pioglitazone activates paraoxonase-2 in the brain: A novel neuroprotective mechanism (2020) (14)
Sham Surgery does not Ameliorate MPTP-Induced Behavioral Deficits in Monkeys (1995) (14)
Metabolic energy capacity of dopaminergic grafts and the implanted striatum in parkinsonian nonhuman primates as visualized with cytochrome oxidase histochemistry. (1997) (13)
Chapter 7 – Pharmacology and Biochemistry of Synaptic Transmission: Classical Transmitters (2014) (13)
Cognitive performance of juvenile monkeys after chronic fluoxetine treatment (2017) (13)
Tyrosine hydroxylase regulation in rat striatal and olfactory tubercle slices--I. Activation induced by exposure to a calcium-free and high-magnesium medium. (1979) (13)
Nonstriatal dopaminergic neurons: role of presynaptic receptors in the modulation of transmitter synthesis. (1977) (13)
Effects of nicotine pretreatment on dopaminergic and behavioral responses to conditioned fear stress in rats: dissociation of biochemical and behavioral effects (2001) (13)
PLASMA AND CSF DOPAMINE METABOLITES IN PSYCHIATRIC PATIENTS: EFFECTS OF PROBENECID AND HALOPERIDOL (1979) (13)
PRELIMINARY REPORT ON THE METABOLISM OF GAMMA-BUTYROLACTONE AND GAMMA-HYDROXYBUTYRIC ACID. (1965) (12)
Effect of morphine treatment and withdrawal on endogenous methionine- and leucine-enkephalin levels in primate brain. (1986) (12)
3-Acetylpyridine results in degeneration of the extrapyramidal and cerebellar motor systems: loss of the dorsolateral striatal dopamine innervation (1990) (12)
TRANSPLANTS OF PRIMATE NEURONS (1986) (12)
Dopamine‐Neurotensin Interactions in Mesocortical Neurons (1992) (12)
Does cyclic AMP-dependent phosphorylation account for the activation of tyrosine hydroxylase produced by depolarization of central dopaminergic neurons? (1979) (12)
3,4-methylenedioxymethamphetamine (MDMA)-induced release of endogenous serotonin from the rat dorsal raphe nucleus in vitro: Effects of fluoxetine and tryptophan (1990) (12)
Chronic gamma-butyrolactone (GBL) treatment: A potential model of dopamine hypoactivity (1979) (11)
Development of A9/A10 dopamine neurons during the second and third trimesters in the African green monkey (2005) (11)
2 – Neuronal Activity, Impulse Flow, and MHPG Production (1983) (11)
Blockade of FG 7142‐Induced Increased Dopamine Utilization by the Glycine/NMDA Receptor Antagonist (+)‐HA 966 (1996) (11)
Norepinephrine concentrating mechanisms in sympathetic nerve trunks. (1970) (11)
Unilateral transplantation of human fetal mesencephalic tissue into the caudate nucleus of patients with parkinson’s disease (1993) (11)
Factors modifying the synthesis of dopamine from tyrosine in pedal ganglia of Mercenaria mercenaria (mollusca) (1972) (11)
Alpha-noradrenergic receptor modulation of the phencyclidine- and delta9-tetrahydrocannabinol-induced increases in dopamine utilization in rat prefrontal cortex. (1998) (11)
Effects of nigrustriatal pathway stimulation and tropolone on plasma concentration of 3,4-dihyuroxyphenylacetic acid (1977) (11)
The subcellular localization of noradrenaline and dopamine in bovine superior cervical ganglion. (1973) (11)
Susceptibility to a parkinsonian toxin varies during primate development (2012) (10)
Relationships between behavioral rhythms, plasma corticosterone and hypothalamic circadian rhythms. (1986) (10)
Biochemical analysis of caudate nucleus biopsy samples from parkinsonian patients (1988) (10)
Transplantation of fetal neurons in primates. (1988) (9)
Metabolism of (1-14C)gamma-hydroxybutyric acid by rat brain after intraventricular injection. (1975) (9)
Tyrosine hydroxylase: Allosteric activation induced by stimulation of central noradrenergic neurons (2004) (9)
gamma-Hydroxybutyrate: effects on nonstriatal dopaminergic neurons. (1977) (9)
Intrastriatal Grafts from Multiple Donors do not Result in a Proportional Increase in Survival of Dopamine Neurons in Nonhuman Primates (1998) (8)
Guanine nucleotide binding proteins and the regulation of cyclic AMP synthesis in NS20Y neuroblastoma cells: role of D1 dopamine and muscarinic receptors (1991) (8)
Presynaptic dopamine receptors: Insensitivity to kainic acid and the development of supersensitivity following chronic haloperidol (1980) (8)
A Potential Compensatory Role for Endogenous Striatal Tyrosine Hydroxylase-Positive Neurons in a Nonhuman Primate Model of Parkinson's Disease (2015) (8)
Chronic clozapine, but not haloperidol, alters the response of mesoprefrontal dopamine neurons to stress and clozapine challenges in rats (1999) (8)
Effect of anesthetic doses of gamma-hydroxybutyrate on the acetylcholine content of rat brain. (1976) (8)
CHAPTER 9 – Pharmacology and Biochemistry of Synaptic Transmission: Classic Transmitters (2004) (8)
Noradrenergic activity in anticipatory nausea. (1992) (8)
PLASMA DOPAMINE METABOLITES: USEFUL INDICES OF CENTRAL DOPAMINE METABOLISM? (1979) (8)
Sympathetic neurotransmitter metabolism in Hirschsprung's disease. (1975) (7)
Dopaminergic neurons: Reversal of effects elicited by γ-butyrolactone by stimulation of the nigro-neostriatal pathway (1976) (7)
Elevated cerebrospinal fluid levels of 5-hydroxytryptamine following experimental spinal cord trauma (1976) (7)
Yohimbine potentiation of reserpine blepharoptosis. (1962) (7)
Tryptophan pretreatment augmentation of p-chloroamphetamine-induced serotonin and dopamine release and reduction of long-term neurotoxicity. (1994) (7)
Segmental norepinephrine and dopamine levels in cat spinal cord. (1977) (7)
Phencyclidine Model of Frontal Cortical Dysfunction in Nonhuman Primates (2000) (7)
Regulation of A8 dopomine neurons by smuatostatin (1988) (7)
Intramedullary serotonin patters following experimental spinal cord trauma. (1977) (6)
Central noradrenergic neurons: studies on the mechanism of the in vivo activation of tyrosine hydroxylase (1981) (6)
Accumulation of 3H-homovanillic acid in rabbit brain and cerebrospinal fluid following intravenous 3H-L-dopa. (1974) (6)
Comparison of Neurotoxicity following Repeated Administration of L-Dopa, D-Dopa, and Dopamine to Embryonic Mesencephalic Dopamine Neurons in Cultures Derived from Fisher 344 and Sprague-Dawley Donors (1997) (6)
EFFECTS OF ANGIOTENSIN-II AND ANGIOTENSIN-III ON CATECHOLAMINE BIOSYNTHESIS (1977) (6)
Variations in noradrenaline output with respect to stimulus frequency, train length and origin of the transmitter. (1972) (6)
Norepinephrine release from nerve terminals within the rabbit superior cervical ganglion (2004) (6)
Dopaminergic neurons: effects elicited by gamma-hydroxybutyrate are reversed by picrotoxin. (1977) (6)
Effects of desipramine on noradrenaline uptake into isolated nerve granules. (1968) (6)
NORADRENERGIC NEURONS: POST-STIMULATION INCREASE IN CATECHOLAMINE BIOSYNTHESIS (1978) (6)
Dopamine Autoreceptors: Studies on their Distribution and Mode of Action (1986) (6)
Dopamine-neurotensin interactions in mesocortical neurons. Evidence from microdialysis studies. (1992) (5)
Sensitization to the locomotor activating effects of cocaine following cocaethylene-preexposure (1996) (5)
Fetal Grafts in Parkinson's Disease (1999) (5)
( S )-( 2 )-HA-966 , a g-Hydroxybutyrate-Like Agent , Prevents Enhanced Mesocorticolimbic Dopamine Metabolism and Behavioral Correlates of Restraint Stress , Conditioned Fear and Cocaine Sensitization 1 (1997) (5)
Synthesis and release of noradrenaline and dopamine from discrete regiions of monkey brain. (1969) (4)
Identification of Novel Variants oftrkC mRNA Transcripts in Brain of African Green Monkeys (1997) (4)
Neurochemical Systems in the Central Nervous System (2011) (4)
Regional brain levels of gamma-hydroxybutyrate in Huntington's disease. (1979) (4)
Restoration of Dopamine Transporter Density in the Striatum of Fetal Ventral Mesencephalon-Grafted, but not Sham-Grafted, Mptp-Treated Parkinsonian Monkeys (1996) (4)
Increase in plasma 3-methoxy-4-hydroxyphenethyleneglycol following stimulation of the nucleus locus coeruleus [proceedings]. (1979) (4)
ROLE OF THE NUCLEUS LOCUS COERULEUS IN SYMPATHETHIC AND CENTRAL NORADRENERGIC ACTIVATION AS REFLECTED BY CHANGES IN THE NOREPINEPHRINE METABOLITE 3-METHOXY-4-HYDROXYPHENETHYLENEGLYCOL (MHPG) IN RATS (1979) (4)
DOPAMINE METABOLITES IN BRAIN REGIONS OF SCHIZOPHRENICS (1979) (4)
In Situ Hybridization Histochemistry of Tyrosine Hydroxylase Messenger RNA in Rat Brain (1988) (4)
CSF GABA in psychotic disorders (2004) (4)
Effects of Antipsychotic Drugs on Dopamine Release and Metabolism in the Central Nervous System (2000) (4)
Regional inhibitory effect of ethanol on monoamine synthesis regulation within the brain. (1980) (4)
Proceedings: Effects of alterations in impulse flow on transmitter metabolism in central dopaminergic neurons. (1974) (4)
A sensitive method for quantitation of gamma-hydroxybutyric acid and gamma-butyrolactone in brain by electron capture gas chromatography. (1975) (4)
Serotonin neurons: a synaptic mechanism for the reuptake of serotonin. (1974) (3)
Precursor Availability and Function of Midbrain Dopaminergic Neurons (1988) (3)
Deprenyl: pharmacological aspects of its clinical effects (1993) (3)
Is There a Function for Protein Carboxylmethylation in the Nervous System (1986) (3)
14C-homovanillic acid in the cerebrospinal fluid of parkinsonian patients after intravenous 14C-L-dopa. (1976) (3)
Avian nocturnal hyperactivity: Neurotransmitter metabolism in the basal ganglia (1980) (3)
Grafts of Dopamine Neurons Can Send Neurites to the Striatum Under GDNF Inducement in a Nonhuman Primate (2009) (3)
Inhibition by gamma-hydroxybutyrate of chlorpromazine-induced increase in homovanillic acid. (1973) (3)
Tyrosine hydroxylase activation and transmitter release from central noradrenergic neurons by electrical field stimulation (2004) (2)
Some physiological and pharmacological characteristics of the stimulus induced release of norepinephrine from the rabbit superior cervical ganglion (2004) (2)
25 – REGULATION OF CATECHOLAMINE SYNTHESIS IN RABBIT PORTAL VEIN (1977) (2)
ACTIVATION OF TYROSINE HYDROXYLASE AND DOPAMINE METABOLITE ACCUMULATION IN THE PRIMATE CINGULATE CORTEX FOLLOWING CHRONIC HALOPERIDOL (1979) (2)
Co-Grafts in Dopamine-Depleted Primates: Preliminary Results and Theoretical Issues Related to Human Applications for Parkinson’s Disease (1995) (2)
BENZODIAZEPINE WITHDRAWAL INCREASES BRAIN MHPG: RELEVANCE TO MECHANISMS OF OPIATE WITHDRAWAL, ANXIETY AND PANIC (1984) (2)
Gamma-hydroxybutyrate and control of dopaminergic neurons. (1975) (1)
Biochemical and Immunohistochemical Characterization of Human Fetal Ventral Mesencephalon (1992) (1)
Reversal of Experimental Parkinsonism in African Green Monkeys Following Fetal Dopamine Neuron Transplantation (1988) (1)
Quantitative Behavioral Assessment Methods for the Analysis of Graft-Induced Motor and Cognitive Function in the MPTP-Treated Parkinsonian Monkey (1992) (1)
CLINICAL STUDIES OF THE GABA SYSTEM IN PSYCHIATRIC DISORDERS (1982) (1)
Inverse relationship between GABA and gamma-hydroxybutyrate levels in striatum of rat injected with kainic acid. (1979) (1)
NMDA receptor hypofunction and animal models of schizophrenia (2000) (1)
Lidocaine selectively diminishes medullary serotonin metabolism in the rat (1981) (1)
Other Interneuronal Signals (2009) (1)
Effects of pharmacologic sympathectomy on gut hypertrophy in enterectomized rats. (1975) (1)
P.3.d.019 Asenapine improves cognition and cortical serotonergic function in monkeys with phencyclidine-induced impairment (2009) (1)
Synaptic Transmission: Intercellular Signaling (2007) (1)
Heroin and Other Opiates (2009) (1)
924 – CLINICAL STUDIES OF GAMMA-HYDROXYBUTYRATE IN CEREBRAL PALSY (1977) (1)
Transplantation advances in parkinson's disease (1989) (1)
Effects of nigrostriatal pathway stimulation and tropolone on plasma concentration of 3,4-dihydroxyphenylacetic acid. (1977) (1)
Perinatal nicotine exposure disrupts short-term memory in a spontaneous object recognition task (2000) (1)
Corrigendum to “prenatal cocaine exposure enhances responsivity of locus coeruleus norepinephrine neurons: Role of autoreceptors” [Neuroscience 147 (2007) 419–427] (2008) (0)
Pregnancy, a Risky Time: Keep Calm, Clean, and Carry On! (2013) (0)
Adrenergic Neurotransmission (1969) (0)
3. Interaction of psychotropic drugs with agents employed in clinical anesthesia. (1967) (0)
The action of chlorpromazine on tyrosine hydroxylase in postganglionic sympathetic nerve. (1968) (0)
The ethics of research using human fetal tissue: (II) (1990) (0)
Acceleration of the rate limiting step in norepinephrine biosynthesis by potassium (1970) (0)
Catecholamine biosynthesis in vascular tissue (1970) (0)
Treatments for Neurological or Psychiatric Disorders: Principles of Central Nervous System Drug Development (2009) (0)
Coordinated expression of dopamine transporter and vesicular monoamine transporter in the primate striatum during development (2013) (0)
Expression Of A Novel TRK C Receptor Isoform With Truncated Extracellular Domain In Fetal And Adult Monkey Brains (1994) (0)
Sleep 1980. Circadian rhythms, dreams, noise and sleep, neurophysiology, therapy (1982) (0)
Recreational Psychoactive Drugs (2009) (0)
Regulation of A8 dopamine neurons by somatostatin. (1988) (0)
Metabolic Energy Capacity of Dopaminergic Grafts and the Implanted Striatum in Parkinsonian Nonhuman Primates as Visualized with Cytochrome Oxidase Histochemistry (1997) (0)
Ac ce pte d M an us cri pt Primate phencyclidine model of schizophrenia : sex-specific effects on cognition , BDNF , spine synapses and dopamine turnover in dorsolateral prefrontal cortex (2014) (0)
Antidepressants and Anxiolytics (2009) (0)
Supersensitivity of pre synaptic dopamine receptors following chronic treatment with fluphenazine (1976) (0)
FORMATIONOF DOPAMINEAND NORADRENALINEINRATVAS DEFERENS: COMPARISONWITH GUINEA-PIGVAS DEFERENS (1975) (0)
Activation by Cyclic 3': 5'-Adenosine Mo) Hydroxylase in the Rat Brain (synaptosomes/enzyme regulation/catecholamine synth4 (2016) (0)
Biochemical Changes Induced by Embryonic Substantia Nigra Transplanted to the Striatum of Parkinsonian Monkeys (1992) (0)
Principles and Methods of Behavioral Pharmacology (2009) (0)
220 The neurotensin agonist PD 149163 induces Fos protein expression in the prefrontal cortex: Similarities to atypical antipsychotic drugs (1997) (0)
Comprar Introduction To Neuropsychopharmacology | Iversen, Leslie L. | 9780195380538 | Oxford University Press (2009) (0)
Studies on the distribution and charactristic of dopamine autoreceptors in the brain (1985) (0)
Cognitive deficits and cortical dopamine dysfunction in a primate model of schizophrenia (1998) (0)
in Rhesus Monkeys Orbital Prefrontal Cortex Impair Affective Processing Combined Unilateral Lesions of the Amygdala and (2015) (0)
Cannabinoid effects on neurocognition: Implications for psychosis (2002) (0)
Cellular and Molecular Foundations of Neuropsychopharmacology (2009) (0)
Regional distribution of GABA, glutamic acid decarboxylase, dopamine metabolites, and high-affinity choline accumulation in the brain of the white-throated sparrow: relationship to avian nocturnal hyperactivity (1979) (0)
Unilateral caudate implantation of fetal substantia nigra in four patients with parkinsonism (1991) (0)
Dopamine Receptor-Deficient Mice 2 Striatum of D Facilitated Glutamatergic Transmission in the (2015) (0)

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