Royston Jefferis
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(Suggest an Edit or Addition)Royston Jefferis's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Post-translational modifications in the context of therapeutic proteins (2006) (865)
- Glycosylation as a strategy to improve antibody-based therapeutics (2009) (763)
- Comparison of the effector functions of human immunoglobulins using a matched set of chimeric antibodies (1987) (633)
- Structural analysis of human IgG-Fc glycoforms reveals a correlation between glycosylation and structural integrity. (2003) (630)
- Glycosylation of Recombinant Antibody Therapeutics (2008) (502)
- Evaluation of monoclonal antibodies having specificity for human IgG sub-classes: results of an IUIS/WHO collaborative study. (1992) (368)
- IgG‐Fc‐mediated effector functions: molecular definition of interaction sites for effector ligands and the role of glycosylation (1998) (329)
- Recombinant antibody therapeutics: the impact of glycosylation on mechanisms of action. (2009) (320)
- The influence of glycosylation on the thermal stability and effector function expression of human IgG1-Fc: properties of a series of truncated glycoforms. (2000) (317)
- Selective IgG subclass deficiency: quantification and clinical relevance (1990) (262)
- Isotype and glycoform selection for antibody therapeutics. (2012) (240)
- Structure of human IgM rheumatoid factor Fab bound to its autoantigen IgG Fc reveals a novel topology of antibody—antigen interaction (1997) (218)
- Role of Oligosaccharide Residues of IgG1-Fc in FcγRIIb Binding* (2001) (217)
- Multiple interactions of IgG with its core oligosaccharide can modulate recognition by complement and human Fc gamma receptor I and influence the synthesis of its oligosaccharide chains. (1996) (211)
- Antibody therapeutics: (2007) (199)
- Interaction sites on human IgG-Fc for FcγR: current models (2002) (195)
- Biopharmaceutical production in plants: problems, solutions and opportunities. (2005) (186)
- Aglycosylation of human IgG1 and IgG3 monoclonal antibodies can eliminate recognition by human cells expressing Fc gamma RI and/or Fc gamma RII receptors. (1989) (174)
- Differential glycosylation of polyclonal IgG, IgG-Fc and IgG-Fab isolated from the sera of patients with ANCA-associated systemic vasculitis. (2006) (173)
- A comparative study of the N-linked oligosaccharide structures of human IgG subclass proteins. (1990) (162)
- Comparative structural study of the N-linked oligosaccharides of human normal and pathological immunoglobulin G. (1987) (160)
- Human Fc gamma RI and Fc gamma RII interact with distinct but overlapping sites on human IgG. (1991) (153)
- Human immunoglobulin allotypes (2009) (146)
- Aspects of the molecular structure of IgG subclasses. (1986) (141)
- Monoclonal antibodies (McAbs) to determinants on human gamma chains: properties of antibodies showing subclass restriction or subclass specificity. (1982) (130)
- Taking immunogenicity assessment of therapeutic proteins to the next level. (2011) (130)
- Contrasting glycosylation profiles between Fab and Fc of a human IgG protein studied by electrospray ionization mass spectrometry. (2007) (116)
- Interaction sites on human IgG-Fc for FcgammaR: current models. (2002) (116)
- A protein structural change in aglycosylated IgG3 correlates with loss of huFcγR1 and hufcγR111 binding and/or activation (1990) (115)
- Mapping and comparison of the interaction sites on the Fc region of IgG responsible for triggering antibody dependent cellular cytotoxicity (ADCC) through different types of human Fc gamma receptor. (1992) (114)
- Complete amino acid sequences of variable regions of two human IgM rheumatoid factors, BOR and KAS of the Wa idiotypic family, reveal restricted use of heavy and light chain variable and joining region gene segments (1987) (113)
- Localisation of the monocyte-binding region on human immunoglobulin G. (1986) (107)
- Glycosylation of human IgG-Fc: influences on structure revealed by differential scanning micro-calorimetry. (1999) (100)
- Structural Determinants of Unique Properties of Human IgG4-Fc (2014) (99)
- Incidence of three cross-reactive idiotypes on human rheumatoid factor paraproteins. (1988) (98)
- Hypogalactosylation of serum IgG in patients with ANCA‐associated systemic vasculitis (2002) (96)
- Butyrate increases production of human chimeric IgG in CHO-K1 cells whilst maintaining function and glycoform profile. (2001) (96)
- Anti‐neutrophil cytoplasm antibody IgG subclasses in Wegener's granulomatosis: a possible pathogenic role for the IgG4 subclass (2004) (96)
- The solution conformations of the subclasses of human IgG deduced from sedimentation and small angle X-ray scattering studies. (1987) (95)
- Role of oligosaccharide residues of IgG1-Fc in Fc gamma RIIb binding. (2001) (94)
- Posttranslational Modifications and the Immunogenicity of Biotherapeutics (2016) (90)
- Glycosylation and Fc receptors. (2014) (89)
- Sialylation of human IgG-Fc carbohydrate by transfected rat alpha2,6-sialyltransferase. (2001) (81)
- Oligosaccharide‐protein interactions in IgG can modulate recognition by Fcγ receptors (1995) (79)
- Idiotypic and subgroup analysis of human monoclonal rheumatoid factors. Implications for structural and genetic basis of autoantibodies in humans. (1988) (77)
- Engagement of CD40 lowers the threshold for activation of resting B cells via antigen receptor (1993) (76)
- Quantitation of the oligosaccharides of human serum IgG from patients with rheumatoid arthritis: a critical evaluation of different methods. (1998) (75)
- IgG1 heavy chain-coding gene polymorphism (G1m allotypes) and development of antibodies-to-infliximab (2009) (75)
- IgG4 autoantibodies induce dermal–epidermal separation (2007) (72)
- Control of IgG/Fc glycosylation: a comparison of oligosaccharides from chimeric human/mouse and mouse subclass immunoglobulin Gs. (1993) (69)
- Relationship between the Papain Sensitivity of Human γG Immunoglobulins and their Heavy Chain Subclass (1968) (68)
- Effects of HIV infection on VH3 (D12 idiotope) B cells in vivo. (1994) (65)
- Structure-function relationships of the variable domains of monoclonal antibodies approved for cancer treatment. (2007) (64)
- IgG subclass distribution of autoantibodies to DNA and to nuclear ribonucleoproteins in autoimmune diseases. (1984) (61)
- Molecular definition of interaction sites on human IgG for Fc receptors (huFcγR) (1990) (59)
- Lymphoma Driver Mutations in the Pathogenic Evolution of an Iconic Human Autoantibody (2020) (56)
- Neutrophil FcγRIIIb allelic polymorphism in anti‐neutrophil cytoplasmic antibody (ANCA)‐positive systemic vasculitis (2000) (56)
- Expression of VHIII-associated cross-reactive idiotype on human B lymphocytes. Association with staphylococcal protein A binding and Staphylococcus aureus Cowan I stimulation. (1991) (54)
- Properties of monoclonal antibodies to human immunoglobulin kappa and lambda chains. (1981) (54)
- Human antibodies elicited by a pneumococcal vaccine express idiotypic determinants indicative of V(H)3 gene segment usage. (1998) (53)
- Site-specific glycosylation of an aglycosylated human IgG1-Fc antibody protein generates neoglycoproteins with enhanced function. (2003) (52)
- Development of a highly-sensitive multi-plex assay using monoclonal antibodies for the simultaneous measurement of kappa and lambda immunoglobulin free light chains in serum and urine. (2013) (52)
- Glycosylation of antibody molecules: structural and functional significance. (1996) (50)
- Evaluation of monoclonal antibodies having specificity for human IgG subclasses: results of the 2nd IUIS/WHO collaborative study. (1992) (49)
- Multiple binding sites on the CH2 domain of IgG for mouse FcγR11 (1992) (46)
- Chimeric IgG4 PR3‐ANCA induces selective inflammatory responses from neutrophils through engagement of Fcγ receptors (2009) (45)
- The Antibody Repertoire of Early Human B Cells (1990) (43)
- Skewed Fc glycosylation profiles of anti-proteinase 3 immunoglobulin G1 autoantibodies from granulomatosis with polyangiitis patients show low levels of bisection, galactosylation, and sialylation. (2015) (43)
- Recognition sites on human IgG for Fcγ receptors: the role of glycosylation (1995) (42)
- Aglycosylated chimaeric human IgG3 can trigger the human phagocyte respiratory burst. (1993) (42)
- Structural studies of immunoglobulins—I. The role of cysteine in papain hydrolysis (1967) (42)
- The separation of human serum IgG into subclass fractions by immunoaffinity chromatography and assessment of specific antibody activity. (1984) (41)
- Restricted light chain subgroup expression on human rheumatoid factor paraproteins determined by monoclonal antibodies. (1986) (41)
- Selective expression of a VHIV subfamily of immunoglobulin genes in human CD5+ B lymphocytes from cord blood (1991) (41)
- Effector mechanisms activated by human IgG subclass antibodies: clinical and molecular aspects. Review article. (1994) (40)
- Expression and characterization of truncated forms of humanized L243 IgG1 (2000) (40)
- The monocyte binding domain(s) on human immunoglobulin G. (1984) (39)
- Distinctive role of IgG1 and IgG3 isotypes in Fc gamma R-mediated functions. (1989) (39)
- Glycosylation of human IgG antibodies: Relevance to therapeutic applications (2002) (38)
- IgG4 as the predominant autoantibody in sera from patients with active state of pemphigus vulgaris (2004) (38)
- Molecular recognition of antibody (IgG) by cellular Fc receptor (FcRI). (1988) (38)
- Evaluation of monoclonal antibodies with specificity for human IgA, IgA subclasses and allotypes and secretory component. Results of an IUIS/WHO collaborative study. (1996) (38)
- The incidence of a new human cross-reactive idiotype linked to subgroup VHIII heavy chains. (1990) (38)
- Lymphoproliferation in primary Sjögren's syndrome. Evidence of selective expansion of a B cell subset characterized by the expression of cross-reactive idiotypes. (1993) (36)
- Enhanced sialylation of a human chimeric IgG1 variant produced in human and rodent cell lines. (2016) (35)
- Glycosylation of natural and recombinant antibody molecules. (2005) (35)
- Immunogenic and antigenic epitopes of immunoglobulins. VIII. A human monoclonal rheumatoid factor having specificity for a discontinuous epitope determined by histidine/arginine interchange as residue 435 of immunoglobulin G. (1984) (35)
- Immunogenic and Antigenic Epitopes of Immunoglobulins (1988) (35)
- Mapping the functional topography of Fcγ with monoclonal antibodies: localization of epitopes interacting with the binding sites of Fc receptor on human K cells (1985) (33)
- Glycosylation of antibody therapeutics: optimisation for purpose. (2009) (33)
- The use of anti-IgG monoclonal antibodies in mapping the monocyte receptor site on IgG. (1986) (33)
- Glycosylation of polyclonal and paraprotein IgG in multiple myeloma (1997) (33)
- Aggregation, immune complexes and immunogenicity (2011) (33)
- What is an idiotype? (1993) (32)
- Crystal structure of deglycosylated human IgG4-Fc (2014) (32)
- Activation of human B cells: alternate options for initial triggering and effects of nonmitogenic concentrations of anti-IgM antibodies on resting and activated cells. (1987) (32)
- Immunogenic and antigenic epitopes of immunoglobulins I. Cross-reactivity of murine monoclonal antibodies to human IgG with the immunoglobulins of certain animal species. (1982) (32)
- Glyco-Engineering of Human IgG-Fc to Modulate Biologic Activities. (2016) (31)
- Development of a rapid and quantitative lateral flow assay for the simultaneous measurement of serum κ and λ immunoglobulin free light chains (FLC): inception of a new near-patient FLC screening tool (2017) (31)
- A protein structural change in aglycosylated IgG3 correlates with loss of huFc gamma R1 and huFc gamma R111 binding and/or activation. (1990) (31)
- Interaction of human IgG chimeric antibodies with the human FcRI and FcRII receptors: requirements for antibody-mediated host cell-target cell interaction. (1989) (30)
- Quantitation of human total IgG, kappa IgG and lambda IgG in serum using monoclonal antibodies. (1980) (30)
- Anti‐CD40 plus interleukin‐4‐activated human naive B cell lines express unmutated immunoglobulin genes with intraclonal heavy chain isotype variability (1995) (29)
- The glycosylation of antibody molecules: functional significance. (1993) (29)
- Immunogenic and antigenic epitopes of immunoglobulins--V. Reactivity of a panel of monoclonal antibodies with sub-fragments of human Fc gamma and abnormal paraproteins having deletions. (1983) (29)
- Anti-idiotypic antibody D12 and superantigen SPA both interact with human VH3-encoded antibodies on the external face of the heavy chain involving FR1, CDR2 and FR3. (1998) (28)
- 6 – Structure–function relationships of IgG subclasses (1990) (28)
- Introduction to biological and small molecule drug research and development : theory and case studies (2013) (27)
- Crystallization of a complex between the Fab fragment of a human immunoglobulin M (IgM) rheumatoid factor (RF–AN) and the Fc fragment of human IgG4 (1996) (27)
- Immunogenic and antigenic epitopes of immunoglobulins XVII-monoclonal antibodies reactive with common and restricted idiotopes to the heavy chain of human rheumatoid factors (2004) (27)
- Quantification of cross‐reactive idiotype‐positive rheumatoid factor produced in autoimmune rheumatic diseases. An indicator of clonality and B cell proliferative mechanisms (1991) (26)
- Polyclonal and monoclonal antibody reagents specific for IgG subclasses. (1986) (25)
- A sugar switch for anti-inflammatory antibodies (2006) (25)
- The development of difference turbidimetric analysis for monoclonal antibodies to human IgG. (1980) (24)
- Restricted immunoglobulin variable region gene usage by hybridoma rheumatoid factors from patients with systemic lupus erythematosus and rheumatoid arthritis. (1993) (24)
- Rheumatoid factors, B cells and immunoglobulin genes. (1995) (23)
- Modulation and High Frequency Expression of Autoantibody‐Associated Cross‐Reactive Idiotypes linked to the VhI Subgroup in CD5‐Expressing B Lymphocytes from Patients with Chronic Lymphocytic Leukaemia (B‐CLL) (1993) (23)
- Human Fcγ RI triggering of the mononuclear phagocyte respiratory burst (1993) (22)
- The molecular specificity of IgG-Fc interactions with Fc gamma receptors. (2001) (22)
- Immunogenic and Antigenic Epitopes of Immunoglobulins Binding of Human Monoclonal Anti‐D Antibodies to FcRI on the Monocyte‐Like U937 Cell Line (1988) (22)
- The specificity and reactivity of rheumatoid factors with human IgG. (1989) (22)
- A novel 13C isotopic labelling strategy for probing the structure and dynamics of glycan chains in situ on glycoproteins. (1994) (21)
- Immunogenic and antigenic epitopes of immunoglobulins--VII. The topographical distribution of Fc gamma epitopes and the relationship of an iso-allotypic specificity to the presence of histidine 435. (1984) (21)
- Analysis of immunoglobulins secreted by hybridomas derived from rheumatoid synovia (1990) (21)
- Expression of rheumatoid factor associated cross‐reactive idiotopes by glandular B cells in Sjögren's syndrome (1991) (20)
- Assay restriction profiles of three monoclonal antibodies recognizing the G3m(u) allotype. Development of an allotype specific assay. (1991) (19)
- Qualitative and quantitative expression of VHI associated cross reactive idiotopes within IgM rheumatoid factor from patients with early synovitis. (1990) (19)
- 614. Aspects of stereochemistry. Part XIX. Isopropylidene derivatives of some polyhydric alcohols. Observations on the hydrolytic behaviour and migration of cyclic ketals (1965) (19)
- The structure of a human rheumatoid factor bound to IgG Fc. (1998) (18)
- Studies of human IgD myeloma proteins. Proteolytic digestion patterns. (1977) (17)
- Triggering of monoclonal human lymphoma B cells with antibodies to IgM heavy chains: differences of response obtained with monoclonal as compared to polyclonal antibodies. (1983) (17)
- Glycosylation of human IgG subclass and mouse IgG2b heavy chains secreted by mouse J558L transfectoma cell lines as chimeric antibodies. (1993) (17)
- Chimeric antibodies to proteinase 3 of IgG1 and IgG3 subclasses induce different magnitudes of functional responses in neutrophils (2007) (17)
- Immunogenic and antigenic epitopes of immunoglobulins. II. Antigenic differences between secreted and membrane IgG demonstrated using monoclonal antibodies. (1982) (16)
- Recognition sites on human IgG for Fc gamma receptors: the role of glycosylation. (1995) (15)
- Characterisation of anti-IgG monoclonal antibody A57H by epitope mapping. (1997) (15)
- Molecular definition of interaction sites on human IgG for Fc receptors (huFc gamma R). (1990) (15)
- The antibody paradigm: present and future development as a scaffold for biopharmaceutical drugs (2009) (15)
- Detection of free kappa chains in human serum and urine using pairs of monoclonal antibodies reacting with C kappa epitopes not available on whole immunoglobulins. (1983) (15)
- The natural antibody response to E. coli includes antibodies of the IgD class. (1978) (15)
- Structure-function relationships in human immunoglobulins. (1991) (14)
- Structural Determination of the Broadly Reactive Anti-IGHV1-69 Anti-idiotypic Antibody G6 and Its Idiotope (2017) (13)
- Theoretical and ultracentrifugal analysis of immune complex formation between monoclonal antibodies and human IgG. (1982) (13)
- Analysis of rheumatoid factor autoantibodies in patients with essential mixed cryoglobulinaemia and rheumatoid arthritis. (1988) (13)
- Structural Studies of Human IgD Paraproteins (1977) (13)
- Probing of the rheumatoid factor (RF) V gene repertoire in rheumatoid arthritis (RA) by hybridoma clones. (1990) (13)
- Evaluation of Monoclonal Antibodies with Putative Specificity for Human IgG Allotypes (1990) (12)
- More pitfalls in the use of monoclonal antibodies. (1984) (12)
- 2 – Molecular Structure of Human IgG Subclasses (1990) (12)
- Characterisation of epitopes of pan-IgG/anti-G3m(u) and anti-Fc monoclonal antibodies. (2003) (12)
- Monoclonal Antibodies to an Immunoglobulin Allotype Marker Glm(f) (1984) (12)
- Glycosylation of Therapeutic IgGs (2009) (12)
- Too little … and too late? (1983) (11)
- Studies of human IgD myeloma proteins. Circular dichroism of intact protein and some proteolytic fragments. (1977) (11)
- Remodelling the oligosaccharide of human IgG antibodies: effects on biological activities. (1997) (11)
- Monoclonal antibodies against different domains of human IgA: specificities determined by immunoblotting and haemagglutination-inhibition. (1986) (11)
- Human IgG subclass-specific epitopes recognised by murine monoclonal antibodies. (1986) (11)
- Monoclonal Antibodies: Principles and Practise (1997) (11)
- Immunogenic and antigenic epitopes of immunoglobulin--XX. Denaturation of human IgG3 by free radicals. (1987) (10)
- Physical conditions during batch culture of hybridomas in laboratory scale stirred tank reactors. (1985) (10)
- Multiple binding sites on the CH2 domain of IgG for mouse Fc gamma R11. (1992) (10)
- Human immunoglobulin D in colostrum, saliva and amniotic fluid. (1979) (10)
- Immunogenic and antigenic epitopes of Ig. XXV. Monoclonal antibodies that differentiate the Mcg+/Mcg- and Oz+/Oz- C region isotypes of human lambda L chains. (1988) (10)
- Humanized mouse G6 anti-idiotypic monoclonal antibody has therapeutic potential against IGHV1-69 germline gene-based B-CLL (2016) (10)
- A quantitative ELISA for measurement of rheumatoid factor associated cross-reactive idiotypes in serum from patients with rheumatic diseases. (1993) (9)
- A rapid technique for the isolation of human IgD myeloma proteins employing ultragel AcA34. (1976) (9)
- The antibody repertoire of early human B cells. III. Expression of cross-reactive idiotopes characteristic of certain rheumatoid factors and identifying V kappa III, VHI, and VHIII gene family products. (1990) (9)
- Specificity and Idiotope Expression of IgM Produced by CD5+ and CD5− Cord Blood B‐Cell Clones a (1992) (9)
- Development of a highly-sensitive multiplex assay using monoclonal antibodies for the simultaneous measurement of kappa and lambda immunoglobulin free light chains in serum and urine (2013) (9)
- Modulation of FcγR and human complement activation by IgG3-core oligosaccharide interactions (1996) (9)
- Activation of B chronic lymphocytic leukaemia cells by Branhamella catarrhalis. (1987) (8)
- Monoclonal antibodies to human IgG: reaction characteristics in the centrifugal analyzer. (1981) (8)
- IgG subclass serum levels in juvenile chronic arthritis. (1986) (8)
- Subclasses of IgG on the surface of human lymphocytes: a study with monoclonal antibodies. (1984) (8)
- The biological significance of specific antibody IgG subclass profiles. (1988) (8)
- CH2 and CH3 domain deleted IgG1 paraproteins inhibit differently Fc receptor mediated binding and cytolysis. (1986) (8)
- Isolation of a VHCλ Fragment on Tryptic Digestion of Human IgD Myeloma Proteins (1975) (8)
- The interaction of IgG with Fc gamma RII: involvement of the lower hinge binding site as probed by NMR. (1993) (7)
- Idiotypy and idiotypic networks: a time to redefine concepts (1993) (7)
- The effects of chemical modification on the antigenicity of a human kappa Bence Jones protein. (1977) (7)
- Aglycosylated antibodies and the methods of making and using them: WO2008030564 (2009) (7)
- Structural Differences within the Gamma G Class of Immunoglobulins (1967) (7)
- Studies on human IgD myeloma proteins. Carbohydrate composition of intact proteins and some proteolytic fragments. (1975) (7)
- Recombinant Proteins and Monoclonal Antibodies. (2017) (7)
- Mutational deglycosylation of the Fc portion of immunoglobulin G causes O‐sulfation of tyrosine adjacently preceding the originally glycosylated site (2010) (6)
- Mode of decomposition of chloro- and fluoro-formates of some carbohydrates and related compounds (1967) (6)
- Monoclonal Antibodies: Mechanisms of Action (2014) (6)
- Physiological influences on recombinant IgG glycosylation. (1998) (6)
- Monoclonal antibodies to the idiotypic determinants of a human IgG paraprotein: evidence for complexity of the anti-idiotype response. (1982) (6)
- Immunogenic and antigenic epitopes of immunoglobulins. XIV. Antigenic variants of IgG4 proteins revealed with monoclonal antibodies. (1986) (6)
- Immunophenotypic and idiotypic characterisation of the leukaemic B-cells from patients with prolymphocytic leukaemia: evidence for a selective expression of immunoglobulin variable region (IGV) gene products. (1993) (5)
- A human kappa Bence Jones protein (subgroup I) showing new amino acid substitutions. (1977) (5)
- Immunogenic and antigenic epitopes of immunoglobulins: studies using monoclonal antibodies to the C γ 3 domain of human immunoglobulin G (1982) (5)
- Studies of human IgD myeloma proteins. Conformational changes induced in the Fc delta fragment on heating or exposure to acid pH. (1978) (5)
- Repertoire of CDS+ and CD5− cord blood B cells: specificity and expression of VH I and VH III associated idiotopes (1992) (5)
- Studies on low molecular weight peptides derived from human gamma-G-globulin. Identification of rheumatoid factor-reactive peptides in proteolytic digests. (1968) (5)
- Antibody and Protein Glycosylation in Health and Disease (1997) (5)
- Oligosaccharide-protein interactions in IgG antibody molecules: structural and functional consequences. (1995) (5)
- Immunogenicity and antigenicity of immunoglobulins: detection of human immunoglobulin light-chain carbohydrate, using concanavalin A. (1987) (5)
- Immunoaffinity chromatography in biorecovery: an application of recombinant DNA technology to generic adsorption processes. (1992) (5)
- A longitudinal study of glycosylation of a human IgG3 paraprotein in a patient with multiple myeloma. (1998) (5)
- Review of Glycosylation Engineering of Biopharmaceuticals: Methods and Protocols (2013) (5)
- Commercial Production of Monoclonal Antibodies: A Guide To Scale-up (1988) (5)
- Bisalbuminaemia Birmingham — A New Variant in an Indian Family: Characterisation and Comparative Studies with Albumin Kashmir (1975) (5)
- Collaborative study of monoclonal antibodies to human IgG subclasses and allotypes. (1982) (4)
- Glycosylation of antibody molecules. A small step for structure, a leap for function. (1995) (4)
- Biologics: structural heterogeneity and immunogenicity. (2017) (4)
- Glycosylation of Antibody Molecules (1995) (4)
- Protein heterogeneity and the immunogenicity of biotherapeutics (2018) (3)
- Routier, F. H. et al. Quantitation of the oligosaccharides of human serum IgG from patients with rheumatoid arthritis: a critical evaluation of different methods. J. Immunol. Methods 213, 113-130 (1998) (3)
- Importance and Monitoring of Therapeutic Immunoglobulin G Glycosylation. (2021) (3)
- Human Fc gamma RI triggering of the mononuclear phagocyte respiratory burst. (1993) (3)
- Quantitation of human IgG glycoforms isolated from rheumatoid sera: A critical evaluation of chromatographic methods (1998) (3)
- Nomenclature of V-region markers. (1995) (3)
- Glycosylation of Recombinant IgG Antibodies and Its Relevance for Therapeutic Applications (2002) (3)
- Surface IgG subclasses in human B cell lymphomas as revealed by monoclonal antibodies. (1984) (3)
- B lymphocytes in contact dermatitis (1980) (3)
- Bisalbuminaemia Birmingham - A New Variant in an Indian Family (1975) (3)
- The antigen antibody reaction (1991) (3)
- A highly conserved conformational idiotope on human IgM rheumatoid factor paraproteins of the Wa cross-reactive idiotype family defined by a monoclonal antibody (2005) (3)
- Criteria for Selection of IgG Isotype and Glycoform of Antibody Therapeutics (2006) (3)
- Expression and characterization of truncated forms of humanized L243 IgG1. Architectural features can influence synthesis of its oligosaccharide chains and affect superoxide production triggered through human Fcgamma receptor I. (2000) (3)
- Immunogenic and antigenic epitopes of immunoglobulins. XVIII. Subpopulations of human lambda chains defined with a panel of monoclonal antibodies. (1986) (3)
- Characterisation of putative monoclonal anti-G3m(u) and anti-G3m(g) reagents and their antigenic determinants. (1994) (3)
- Enhanced Immunomodulatory Effect of Intravenous Immunoglobulin by Fc Galactosylation and Nonfucosylation (2022) (3)
- Monoclonal anti-cross-reactive idiotype antibodies as possible probes for lymphoproliferation in primary Sjögren's syndrome. (1989) (3)
- Pronase digestion of human IgG and Fcδ (1979) (3)
- A human monoclonal IgA rheumatoid factor using the VkIV light chain gene (2004) (2)
- IGG SUBCLASS ANALYSIS OF ANTI-HBS ANTIBODIES PRODUCED IN RESPONSE TO VACCINATION WITH RECOMBINANT HBSAG AND INFECTION WITH THE WILD HEPATITIS B VIRUS (2000) (2)
- IDENTIFICATION OF TWO ANTIGENICALLY DISTINCT b‐NEGATIVE LIGHT CHAINS IN RABBITS UNDERGOING TOTAL b LOCUS SUPPRESSION (1974) (2)
- Characterization of Biosimilar Biologics : The Link between Structure and Functions (2017) (2)
- Immunogenicity and antigenicity of immunoglobulins. XII. Intact light chain and heavy chain isotype-restricted Vk-associated epitopes. (1985) (2)
- Pyridine-catalysed decarboxylation of cis- and trans-4-tert-butylcyclohexyl chloroformate (1967) (2)
- Chapter 4. Antibody Glycosylation (2009) (2)
- A study of ROS induced denaturation of IgG3 using monoclonal antibodies; implications for inflammatory joint disease. (1988) (2)
- Studies on intact variable regions and variable region sub-fragments isolated from a human kappa Bence-Jones protein (sub-group I). (1979) (2)
- Study of proteolytic removal of Fab delta and Fe delta determinants of lymphocyte membrane IgD using a direct rosette assay. (1981) (2)
- Idiotypes as markers for immunoglobulin genes contributing to the production of rheumatoid factors: theoretical and practical implications. (1994) (2)
- PURIFICATION OF MONOCLONAL ANTIBODY FROM CULTURE SUPERNATANT PRODUCED IN HOLLOW FIBRE BIOREACTORS (1992) (2)
- Structure of a human IgM rheumatoid factor complexed with its autoantigen IgG Fc (1996) (1)
- IgGsubclass serum levels injuvenile chronic arthritis (1986) (1)
- 4.20 – Human IgG Glycosylation in Inflammation and Inflammatory Disease (2007) (1)
- The effects of carbamylation on the antigenicity of human immunoglobulin G probed with monoclonal antibodies (1987) (1)
- Qualitative andquantitatve expression ofVHI associated crossreactive idiotopes within IgAM rheumatoid factor frompatients withearly synovitis (1990) (1)
- Molecular specificity and idiotypy of human rheumatoid factors. (1987) (1)
- Immunoglobulin D — antibody or receptor? Part II. Functional aspects (1981) (1)
- Immunogenic and Antigenic Epitopes of Immunoglobulins VI. Application of Monoclonal Antibodies to Human IgG Sub-Classes in Quantitative Assays (1983) (1)
- Structural studies of human immunoglobulin D myeloma proteins: circular-dichroic studies of two intact proteins and enzymically derived fragments. (1977) (1)
- Antibody Posttranslational Modifications (2016) (1)
- Does an antibody molecule act as a template directing (determining) its glycosylation? (1992) (1)
- Activation of effector functions by immune complexes of mouse IgG2a with isotype-specific autoantibodies. (1995) (1)
- Glycosylation heterogeneity in human IgG subclass proteins (1988) (1)
- Human IgG Glycosylation in Inflammation and Inflammatory Disease (2021) (1)
- Immunoglobulin D — antibody or receptor? Part I. Structural features (1981) (1)
- Lectins and glycoimmunology (PP-027) (2010) (1)
- Asasy restriction profiles of three monoclonal antibodies recognizing the G3m(u) allotype (1991) (1)
- Characteristics of monoclonal-antibody-antigen interactions and their application to quantitative techniques. (1981) (1)
- Research monographs in immunology vol. 3. Monoclonal antibodies and T-cell hybridomas edited by G. J. Hämmerling, U. Hämmerling and J. F. Kearney. Elsevier/North-Holland Biomedical Press, 1981. $99.50/Dfl 234.00 (xvi + 604 pages) ISBN 0 444 80351 3. (1982) (1)
- Antigenicity and effector functions of human immunoglobulin G1 proteins having Cγ2 or Cγ3 deletions (1984) (0)
- Comprehensive Immunology: Volume 5. Immunoglobulins (1979) (0)
- Immunoglobulin gene expression in development and disease (1997) (0)
- MonoclonalAntibodiesto HumanlgG: ReactionCharacteristics in the CentrifugalAnalyzer (1981) (0)
- Balb/c monoclonal antibodies to the human G1m(f) allotype: a possible germ line specificity* (1985) (0)
- Crystal structure of recombinant human IgG4 Fc (2013) (0)
- Immunogenic and antigenic epitopes of immunoglobulins: evidence for related variable-region epitopes in a panel of Bence-Jones proteins (1982) (0)
- Effector sites of human immunoglobulin probed with monoclonal antibodies to Fcγ epitopes (1985) (0)
- Immunochemistry: An Advanced Textbook (1979) (0)
- Pronase digestion of human IgG and Fcdelta. (1979) (0)
- CRYSTAL STRUCTURE OF THE HUMAN IGG1 FC-FRAGMENT,GLYCOFORM (M3N2F)2 (2003) (0)
- GALACTOSYLATION OF HUMAN/MOUSE IGG ANTI–NP ANTIBODIES AND ITS DETECTION BY ELISA (1994) (0)
- Fc Protein Engineering (2014) (0)
- University of Birmingham Development of a rapid and quantitative lateral flow assay for the simultaneous measurement of serum and immunoglobulin free light chains (FLC) (2016) (0)
- CRYSTAL STRUCTURE OF THE HUMAN IGG1 FC-FRAGMENT,GLYCOFORM (G2F)2,SG P212121 (2003) (0)
- HUMAN Fcγ EPITOPES AND INTERACTION SITES FOR EFFECTOR MOLECULES (1987) (0)
- Antigenicity and effector functions of human immunoglobulin G1 proteins having C gamma 2 or C gamma 3 deletions. (1984) (0)
- The epitope specificity and idiotypy of monoclonal rheumatoid factors. (1988) (0)
- Contemporary topics in molecular immunology. volume 7: Edited by R A Reisfeld and F P Inman. pp. 425. Plenum Press: New York and London. 1978, £24.83 ur $39.50 (1979) (0)
- Crystal structure of serum-derived human IgG4 Fc (2013) (0)
- Rabbit b4 light chain fragments bearing isotypic and allotypic specificities. (1974) (0)
- WHO/IUIS standardization programme for immunological reagents: Collaborative study of monoclonal antibodies to human IgA (1988) (0)
- Monoclonal antibodies in immunotherapy (2019) (0)
- Use of Monoclonal Antibodies in the Characterisation of Immunoglobulin Classes and Subclasses in Animal Species (1982) (0)
- IN VITRO GLYCOSYLATION OF AN AGLYCOSYLATED IgG-ANTIBODY Fc UNIT AFFORDS NEOGLYCOCONJUGATES WITH ENHANCED FUNCTION (2002) (0)
- Selective Expressionofa VH1V Subfamily ofImmunoglobulinGenes inHuman CD5 + B Lymphocytesfrom Cord Blood (1991) (0)
- Micro-Heterogeneity of Antibody Molecules. (2021) (0)
- Structural and idiotypic relationships between monoclonal antibodies specific for IgG1 (Fc) subclass epitopes (1988) (0)
- The role of IgG1-Fc oligosaccharide residues in FcγRIIb binding (2002) (0)
- What" "d'otype is an i I (1993) (0)
- Structure, Function Relationships within the Human IgG Subclasses (1989) (0)
- The contribution of glycosylation to the stability and function of antibody molecules (2000) (0)
- Crystal structure of deglycosylated serum-derived human IgG4 Fc (2014) (0)
- Erratum to “Modulation of FcγR and human complement activation by IgG3-core oligosaccharide interactions”: [Immunol. Lett. 54 (1996) 101–104]1 (1997) (0)
- Architectural features of human IgG that modulate its catabolic half-life in the rat (2002) (0)
- Structural Determination o f the Broadly Reactive Anti-IGHV 169 Anti-idiotypic Antibody G 6 and Its Idiotope Graphical Abstract Highlights (2017) (0)
- Introns, exons and immunoglobulins (1983) (0)
- A355 Monoclonal Antibodies That Provide a Reliable New Assay for Serum Immunoglobulin FLC in Myeloma (2009) (0)
- The impact of glycosylation on monoclonal antibody potency and stability (2005) (0)
- Crystal structure of a human IgG1 Fc-fragment,high salt condition (2003) (0)
- Architectural features of human IgG that modulate its catabolic half-life in the rat (2002) (0)
- Unique structural features of human IgG4 Fc (2013) (0)
- Control of IgG-Fc glycosylation by its protein structure (2002) (0)
- Antibody-antigen complexes: structure, presentation & immunogenicity (2013) (0)
- Protein heterogeneity and the immunogenicity of biotherapeutics. (2018) (0)
- Isolation of a VHClambda fragment on tryptic digestion of human IgD myeloma proteins. (1975) (0)
- Neoglyconjugate IgG-Fc molecules have enhanced function relative to aglycosylated IgG-Fc (2002) (0)
- Repertoire ofCD5+ andCD5 cordbloodB cells: specificity andexpression ofVHIandVHIIIassociated idiotopes (1992) (0)
- The antibody enigma: Kindt, Thomas J. and J. Donald Capra, Plenum Press, New York, 1984, $35.00 (1985) (0)
- Monoclonal antibodies to idiotypic determinants of a human immunoglobulin paraprotein: evidence for the complexity of idiotype (1982) (0)
- Immunoglobulin G subclass specificity of human Fc receptor II determined using human chimeric anti-5-iodio-4-hydroxy-3-nitrophenacetyl monoclonal antibodies (1988) (0)
- Monoclonal antibodies and immobilized antibodies (1987) (0)
- Modulation of Fc(gamma)R and human complement activation by IgG3-core oligosaccharide interactions. (1996) (0)
- N-glycosylation of the Fc-fragment of human IgG1 is crucial for its structural integrity and Fcg-receptor affinity (2002) (0)
- Galactosylation and sialylation of anti-proteinase 3 antibodies in granulomatosis with polyangiitis is associated with increased inflammatory cytokines (2013) (0)
- Human Antibodies with Specificity for the Spacer Domain of ADAMTS13 Are Derived from VH1-69 Germline Genes. (2007) (0)
- Basic and clinical aspects of IgG subclasses: measurement of serum levels (1986) (0)
- Quantitation of Iggkappa and Igglambda in Normal and Pathological Sera (1982) (0)
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