Robert Laurence Jilka
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Why Is Robert Laurence Jilka Influential?
(Suggest an Edit or Addition)Robert Laurence Jilka's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Bone marrow, cytokines, and bone remodeling. Emerging insights into the pathophysiology of osteoporosis. (1995) (1648)
- Inhibition of osteoblastogenesis and promotion of apoptosis of osteoblasts and osteocytes by glucocorticoids. Potential mechanisms of their deleterious effects on bone. (1998) (1645)
- Nongenotropic, Sex-Nonspecific Signaling through the Estrogen or Androgen Receptors Dissociation from Transcriptional Activity (2001) (1210)
- Matrix-embedded cells control osteoclast formation (2011) (1117)
- Increased bone formation by prevention of osteoblast apoptosis with parathyroid hormone. (1999) (1004)
- Increased osteoclast development after estrogen loss: mediation by interleukin-6 (1992) (837)
- Sex steroids and bone. (2002) (755)
- Increased osteoclast development after estrogen loss: mediation by interleukin-6. (1992) (719)
- 17 beta-estradiol inhibits interleukin-6 production by bone marrow-derived stromal cells and osteoblasts in vitro: a potential mechanism for the antiosteoporotic effect of estrogens. (1992) (690)
- Molecular and cellular mechanisms of the anabolic effect of intermittent PTH. (2007) (629)
- Skeletal Involution by Age-associated Oxidative Stress and Its Acceleration by Loss of Sex Steroids* (2007) (592)
- Chronic elevation of parathyroid hormone in mice reduces expression of sclerostin by osteocytes: a novel mechanism for hormonal control of osteoblastogenesis. (2005) (587)
- Osteoblast Programmed Cell Death (Apoptosis): Modulation by Growth Factors and Cytokines (1998) (568)
- Inhibition of Osf2/Cbfa1 expression and terminal osteoblast differentiation by PPARγ2 (1999) (481)
- Regulation of interleukin-6, osteoclastogenesis, and bone mass by androgens. The role of the androgen receptor. (1995) (455)
- Rosiglitazone causes bone loss in mice by suppressing osteoblast differentiation and bone formation. (2005) (450)
- Interleukin-11: a new cytokine critical for osteoclast development. (1994) (412)
- Divergent Effects of Selective Peroxisome Proliferator-Activated Receptor-γ2 Ligands on Adipocyte Versus Osteoblast Differentiation. (2002) (385)
- Proteasomal Degradation of Runx2 Shortens Parathyroid Hormone-induced Anti-apoptotic Signaling in Osteoblasts (2003) (377)
- Control of Bone Mass and Remodeling by PTH Receptor Signaling in Osteocytes (2008) (366)
- Linkage of decreased bone mass with impaired osteoblastogenesis in a murine model of accelerated senescence. (1996) (350)
- Promotion of osteoclast survival and antagonism of bisphosphonate-induced osteoclast apoptosis by glucocorticoids. (2002) (347)
- Extracellular Matrix Made by Bone Marrow Cells Facilitates Expansion of Marrow‐Derived Mesenchymal Progenitor Cells and Prevents Their Differentiation Into Osteoblasts (2007) (334)
- Essential Requirement of BMPs‐2/4 for Both Osteoblast and Osteoclast Formation in Murine Bone Marrow Cultures from Adult Mice: Antagonism by Noggin (2000) (328)
- Reversal of Bone Loss in Mice by Nongenotropic Signaling of Sex Steroids (2002) (273)
- Cytokines, bone remodeling, and estrogen deficiency: a 1998 update. (1998) (268)
- FoxO-mediated defense against oxidative stress in osteoblasts is indispensable for skeletal homeostasis in mice. (2010) (252)
- Increased Lipid Oxidation Causes Oxidative Stress, Increased Peroxisome Proliferator-activated Receptor-γ Expression, and Diminished Pro-osteogenic Wnt Signaling in the Skeleton* (2009) (234)
- The estrogen receptor-alpha in osteoclasts mediates the protective effects of estrogens on cancellous but not cortical bone. (2010) (234)
- Increased Adipogenesis and Myelopoiesis in the Bone Marrow of SAMP6, a Murine Model of Defective Osteoblastogenesis and Low Turnover Osteopenia (1997) (232)
- The relevance of mouse models for investigating age-related bone loss in humans. (2013) (228)
- Parathyroid Hormone Stimulates Receptor Activator of NFκB Ligand and Inhibits Osteoprotegerin Expression via Protein Kinase A Activation of cAMP-response Element-binding Protein* (2002) (225)
- Divergent effects of selective peroxisome proliferator-activated receptor-gamma 2 ligands on adipocyte versus osteoblast differentiation. (2002) (209)
- Loss of estrogen upregulates osteoblastogenesis in the murine bone marrow. Evidence for autonomy from factors released during bone resorption. (1998) (203)
- Estrogen receptor-α signaling in osteoblast progenitors stimulates cortical bone accrual. (2013) (195)
- Increased interleukin-6 production by murine bone marrow and bone cells after estrogen withdrawal. (1993) (188)
- FoxO proteins restrain osteoclastogenesis and bone resorption by attenuating H2O2 accumulation (2014) (187)
- FOXOs attenuate bone formation by suppressing Wnt signaling. (2013) (187)
- Rescuing replication and osteogenesis of aged mesenchymal stem cells by exposure to a young extracellular matrix (2011) (184)
- Perspective: Quantifying Osteoblast and Osteocyte Apoptosis: Challenges and Rewards (2007) (179)
- Reconstitution of marrow-derived extracellular matrix ex vivo: a robust culture system for expanding large-scale highly functional human mesenchymal stem cells. (2010) (178)
- Biology of the basic multicellular unit and the pathophysiology of osteoporosis. (2003) (171)
- Suppression of Autophagy in Osteocytes Mimics Skeletal Aging* (2013) (163)
- Reversal of bone loss in mice by nongenotropic signaling of sex steroids. (2003) (158)
- Transient Versus Sustained Phosphorylation and Nuclear Accumulation of ERKs Underlie Anti-Versus Pro-apoptotic Effects of Estrogens* (2005) (154)
- Osteocyte apoptosis. (2013) (153)
- A Role for Interleukin-6 in Parathyroid Hormone-Induced Bone Resorption in Vivo1. (1999) (137)
- Inhibin suppresses and activin stimulates osteoblastogenesis and osteoclastogenesis in murine bone marrow cultures. (2002) (134)
- Effect of the purified (Mg2+ + Ca2+)-activated ATPase of sarcoplasmic reticulum upon the passive Ca2+ permeability and ultrastructure of phospholipid vesicles. (1975) (132)
- DNA damage and senescence in osteoprogenitors expressing Osx1 may cause their decrease with age (2017) (129)
- Attenuation of the self-renewal of transit-amplifying osteoblast progenitors in the murine bone marrow by 17 beta-estradiol. (2001) (129)
- Intermittent PTH stimulates periosteal bone formation by actions on post-mitotic preosteoblasts. (2009) (128)
- The effects of androgen deficiency on murine bone remodeling and bone mineral density are mediated via cells of the osteoblastic lineage. (1997) (125)
- Mechanism of ATP hydrolysis by sarcoplasmic reticulum and the role of phospholipids. (1976) (123)
- Intermittent parathyroid hormone administration counteracts the adverse effects of glucocorticoids on osteoblast and osteocyte viability, bone formation, and strength in mice. (2010) (117)
- Estrogens Attenuate Oxidative Stress and the Differentiation and Apoptosis of Osteoblasts by DNA-Binding-Independent Actions of the ERα (2009) (117)
- Old age causes de novo intracortical bone remodeling and porosity in mice. (2017) (114)
- Effect of the mi allele on mast cells, basophils, natural killer cells, and osteoclasts in C57BI/6J mice (1987) (110)
- The Role of Osteocytes in Age-Related Bone Loss (2016) (110)
- New insights into the cellular, biochemical, and molecular basis of postmenopausal and senile osteoporosis: roles of IL-6 and gp130. (1995) (109)
- Decreased oxidative stress and greater bone anabolism in the aged, when compared to the young, murine skeleton with parathyroid hormone administration (2010) (108)
- Demonstration of estrogen and vitamin D receptors in bone marrow-derived stromal cells: up-regulation of the estrogen receptor by 1,25-dihydroxyvitamin-D3. (1993) (105)
- Chromosomal Mapping of Osteopenia‐Associated Quantitative Trait Loci Using Closely Related Mouse Strains (2000) (104)
- Quantification of Vitamin D Receptor mRNA by Competitive Polymerase Chain Reaction in PBMC: Lack of Correspondence with Common Allelic Variants (1997) (101)
- Parathyroid hormone and lipopolysaccharide induce murine osteoblast-like cells to secrete a cytokine indistinguishable from granulocyte-macrophage colony-stimulating factor. (1989) (95)
- The Effects of Aging and Sex Steroid Deficiency on the Murine Skeleton Are Independent and Mechanistically Distinct (2017) (86)
- Estrogen loss upregulates hematopoiesis in the mouse: a mediating role of IL-6. (1995) (85)
- Induction of Osteoblast Differentiation by Selective Activation of Kinase-Mediated Actions of the Estrogen Receptor (2006) (83)
- A role for interleukin-6 in parathyroid hormone-induced bone resorption in vivo. (1999) (81)
- The skeletal effects of glucocorticoid excess override those of orchidectomy in mice. (2004) (73)
- IL-6 is not required for parathyroid hormone stimulation of RANKL expression, osteoclast formation, and bone loss in mice. (2005) (70)
- Continuous Elevation of PTH Increases the Number of Osteoblasts via Both Osteoclast-Dependent and -Independent Mechanisms (2010) (70)
- The Effects of Androgens on Murine Cortical Bone Do Not Require AR or ERα Signaling in Osteoblasts and Osteoclasts (2015) (68)
- Dysapoptosis of Osteoblasts and Osteocytes Increases Cancellous Bone Formation But Exaggerates Cortical Porosity With Age (2014) (65)
- Non-nuclear-initiated actions of the estrogen receptor protect cortical bone mass. (2013) (58)
- Endogenous production of tumor necrosis factor by primary cultures of murine calvarial cells: influence on IL-6 production and osteoclast development. (1994) (55)
- Ornithine transcarbamylase of rat liver. Kinetic, physical, and chemical properties. (1979) (53)
- Passive Ca2+ permeability of phospholipid vesicles and sarcoplasmic reticulum membranes. (1975) (50)
- Commitment to the Osteoblast Lineage Is Not Required for RANKL Gene Expression* (2009) (50)
- Homologous and Heterologous Control of Bone Cell Adenosine 3′,5′-Monophosphate Response to Hormones by Parathormone, Prostaglandin E2, Calcitonin, and 1,25-hydroxycholecalciferol* (1980) (45)
- Functional and molecular changes in colony stimulating factor secretion by osteoblasts. (1989) (42)
- Osteoprotegerin prevents glucocorticoid-induced osteocyte apoptosis in mice. (2011) (41)
- Formation and secretion of fragments of parathormone. Identification of cleavage sites. (1986) (39)
- Formation of bone by isolated, cultured osteoblasts in millipore diffusion chambers (1982) (35)
- Are osteoblastic cells required for the control of osteoclast activity by parathyroid hormone? (1986) (35)
- Sex steroids, cytokines and the bone marrow: new concepts on the pathogenesis of osteoporosis. (1995) (34)
- Role of phosphodiesterase in the parathormone-stimulated adenosine 3',5'-monophosphate response in bone cell populations enriched in osteoclasts and osteoblasts. (1981) (34)
- Estrogens decrease osteoclast number by attenuating mitochondria oxidative phosphorylation and ATP production in early osteoclast precursors (2020) (33)
- Oxidation-specific epitopes restrain bone formation (2018) (33)
- Parathyroid hormone-stimulated development of osteoclasts in cultures of cells from neonatal murine calvaria. (1986) (32)
- Osteocyte RANKL is required for cortical bone loss with age and is induced by senescence (2020) (30)
- Estrogen, cytokines, and the control of osteoclast formation and bone resorption in vitro and in vivo (2005) (29)
- Cleavage of parathyroid hormone to the 1-34 and 35-84 fragments by cathepsin D-like activity in bovine parathyroid gland extracts. (1983) (29)
- The Road to Reproducibility in Animal Research (2016) (29)
- Skeletal inflammation and attenuation of Wnt signaling, Wnt ligand expression, and bone formation in atherosclerotic ApoE-null mice. (2016) (28)
- Amino acid sequence of the precursor region of MOPC-315 mouse immunoglobulin heavy chain. (1977) (27)
- Comparison of bone and parathyroid hormone as stimulators of osteoclast development and activity in calvarial cell cultures from normal and osteopetrotic (mi/mi) mice (1990) (25)
- A collagenolytic response to parathormone, 1,25-dihydroxycholecalciferol D3, and prostaglandin E2 in bone of osteopetrotic (mi/mi) mice. (1983) (25)
- Cytokines, hematopoiesis, osteoclastogenesis, and estrogens (1992) (24)
- Inhibition of parathormone-stimulated bone resorption by type I interferon. (1984) (21)
- Osteoblast progenitor fate and age-related bone loss. (2002) (20)
- Synthesis and glycosylation of the MOPC-46B immunoglobulin in kappa chain in Xenopus laevis oocytes. (1977) (18)
- Estrogens, cytokines, and the pathophysiology of osteoporosis (1994) (18)
- The effect of calcium ion transport ATPase upon the passive calcium ion permeability of phospholipid vesicles. (1977) (18)
- Impaired gastric acid secretion in mast cell-deficient mice. (1990) (18)
- Increased marrow adipogenesis does not contribute to age‐dependent appendicular bone loss in female mice (2020) (16)
- Carbonic anhydrase isozymes of osteoclasts and erythrocytes of osteopetrotic microphthalmic mice. (1985) (14)
- Inhibiting the Inhibitor: A New Route to Bone Anabolism (2009) (12)
- Uptake of (U- 14 C)glucose into subcellular particles of wheat seedling roots. (1972) (12)
- Apoptosis of Bone Cells (2008) (12)
- A novel locus on the X chromosome regulates post-maturity bone density changes in mice. (2007) (11)
- Synthesis and processing of the mouse MOPC-321 k chain in Xenopus laevis oocytes (1979) (10)
- Evidence for two pathways for stimulation of collagenolysis in bone (1985) (10)
- Response to Windahl et al. (2006) (8)
- Formation and Secretion of Fragments of Parathormone (1986) (8)
- Parathyroid hormone and corticosteroid-induced osteoporosis (1998) (7)
- Protein-Protein Interactions and the Functional States of Sarcoplasmic Reticulum Membranes (1977) (7)
- A Neutralizing Antibody Targeting Oxidized Phospholipids Promotes Bone Anabolism in Chow‐Fed Young Adult Mice (2020) (7)
- Procollagenase associated with the noncalcified matrix of bone and its regulation by parathyroid hormone. (1989) (7)
- Precursor sequence of MOPC-315 mouse immunoglobulin heavy and light chains. (1979) (6)
- Formation of parathormone 8–34 by cathepsin-D digestion of parathormone and its efficacy as a hormone antagonist (1986) (6)
- Stimulation of collagenolytic enzyme release from cultured bone cells of normal and osteopetrotic (mi/mi) mice by parathyroid hormone and lipopolysaccharide. (1989) (3)
- Ability of Circulating Human Hematopoietic Lineage Negative Cells to Support Hematopoiesis (2015) (3)
- Cell-free translation of immunoglobulin messenger RNA from MOPC-315 plasmacytoma and MOPC-315 NP-1, a variant synthesizing only heavy chain. (1977) (3)
- Elevation of the unfolded protein response increases RANKL expression (2020) (2)
- Extraction of polysaccharides from wheat seedlings with sodium dodecyl sulfate (1975) (2)
- Effect of Vitamin D on Cultured Bone Cells (1984) (1)
- Age-related bone loss: The cost of p53-mediated tumor suppression? (2002) (1)
- Estrogen withdrawal in-vitro or in-vivo augments interleukin-6 production by bone and bone marrow cells in response to resorbing agents (1992) (1)
- Estrogens on Cancellous But Not Cortical Bone The Estrogen Receptor-{alpha} in Osteoclasts Mediates the Protective Effects of (2010) (1)
- Interleukin-6 neutralizing antibody administration prevents osteoclastogenic response to ovariectomy in the mouse (1992) (1)
- Relative sensitivity of kidney and bone to the amino-terminal fragment b-PTH (1–30) of native bovine parathyroid hormone: Implications for assessment of bioactivity of parathyroid hormone fragments in vivo and in vitro (1983) (1)
- Cellular actions of parathyroid hormone on bone (2020) (1)
- Stem cells in bone formation growth and remodeling (2002) (1)
- Increase in marrow progenitors accounts for osteoclastogenic response to ovariectomy in the mouse (1992) (1)
- Age-related bone loss: lessons from the osteoporotic SAMP6 mouse model (2004) (0)
- Studies on the intermediates involved in hemicellulose biosynthesis (1972) (0)
- Matrix degradation during hormone-stimulated resorption of normal and osteopetrotic bone. Abstr. (1982) (0)
- INCREASED MARROW ADIPOGENESIS IN THE MURINE MODEL OF DEFECTIVE OSTEOBLASTOGENESIS 109 (1997) (0)
- Procedes de detection d'agents regulant l'apoptose destines a la therapie anabolisante osseuse et utilisations de tels agents (1999) (0)
- Homologous and heterologous control of bone cell adenosine 3',5'-monophosphate response to hormones by parathoromone, prostaglandin E2, calcitonin, and 1,25-dihydroxycholecalciferol. (1980) (0)
- Oxidation-specific epitopes restrain bone formation (2018) (0)
- Holey Bones ” : How osteocytes might cause the development of cortical bone porosity (2014) (0)
- Author response for "A Neutralizing Antibody Targeting Oxidized Phospholipids Promotes Bone Anabolism in Chow‐Fed Young Adult Mice" (2020) (0)
- List of Contributors (2020) (0)
- The study of skeletal aging is coming of age: A forum on aging and skeletal health (2011) (0)
- Synthesis and processing of the mouse MOPC-321 kappa chain in Xenopus laevis oocytes. (1979) (0)
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