Richard M. Lawn
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Richard M. Lawnbiology Degrees
Biology
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#14570
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Molecular Biology
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#1728
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Biochemistry
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#1962
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Biology
Richard M. Lawn's Degrees
- PhD Biochemistry University of California, Berkeley
- Bachelors Chemistry University of California, Berkeley
Why Is Richard M. Lawn Influential?
(Suggest an Edit or Addition)Richard M. Lawn's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- cDNA sequence of human apolipoprotein(a) is homologous to plasminogen (1987) (1814)
- The structure and evolution of the human β-globin gene family (1980) (1042)
- Characterization of the human factor VIII gene (1984) (937)
- Structure of human factor VIII (1984) (831)
- The Tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathway. (1999) (765)
- The isolation and characterization of linked δ- and β-globin genes from a cloned library of human DNA (1978) (676)
- Expression of active human factor VIII from recombinant DNA clones (1984) (657)
- Base composition-independent hybridization in tetramethylammonium chloride: a method for oligonucleotide screening of highly complex gene libraries. (1985) (643)
- ABCA1 Is the cAMP-inducible Apolipoprotein Receptor That Mediates Cholesterol Secretion from Macrophages* (2000) (555)
- ABCA1. The gatekeeper for eliminating excess tissue cholesterol. (2001) (460)
- ABC1 gene expression and ApoA-I-mediated cholesterol efflux are regulated by LXR. (2000) (436)
- The structure of eight distinct cloned human leukocyte interferon cDNAs (1981) (431)
- Partial amino acid sequence of apolipoprotein(a) shows that it is homologous to plasminogen. (1987) (426)
- The serum concentration of active transforming growth factor-β is severely depressed in advanced atherosclerosis (1995) (416)
- Human lipoprotein lipase complementary DNA sequence. (1987) (413)
- Proliferation of human smooth muscle cells promoted by lipoprotein(a). (1993) (391)
- Activation of transforming growth factor-β is inhibited in transgenic apolipoprotein(a) mice (1994) (381)
- The nucleotide sequence of the human β-globin gene (1980) (353)
- Cloning and sequencing of human cholesteryl ester transfer protein cDNA (1987) (341)
- Distribution of factor VIII mRNA and antigen in human liver and other tissues (1985) (296)
- Molecular cloning and characterization of the human β-like globin gene cluster (1980) (288)
- Atherogenesis in transgenic mice expressing human apolipoprotein(a) (1992) (280)
- The molecular genetics of human hemoglobins. (1980) (259)
- Construction and characterization of an active factor VIII variant lacking the central one-third of the molecule. (1986) (243)
- Characterisation of deletions which affect the expression of fetal globin genes in man (1979) (217)
- Lipoprotein(a) and atherosclerosis. (1991) (212)
- Genetic mapping and diagnosis of haemophilia A achieved through a BclI polymorphism in the factor VIII gene (1985) (204)
- Detection and sequence of mutations in the factor VIII gene of haemophiliacs (1985) (195)
- Membrane Lipid Domains Distinct from Cholesterol/Sphingomyelin-Rich Rafts Are Involved in the ABCA1-mediated Lipid Secretory Pathway* (2001) (194)
- The LXR ligand T0901317 induces severe lipogenesis in the db/db diabetic mouse Published, JLR Papers in Press, August 16, 2003. DOI 10.1194/jlr.M300135-JLR200 (2003) (193)
- DNA polymorphism at the locus for human cholesteryl ester transfer protein (CETP) is associated with high density lipoprotein cholesterol and apolipoprotein levels (1989) (189)
- Chromosomal localization of human leukocyte, fibroblast, and immune interferon genes by means of in situ hybridization. (1982) (183)
- 5' control regions of the apolipoprotein(a) gene and members of the related plasminogen gene family. (1993) (174)
- The sequence of human serum albumin cDNA and its expression in E. coli. (1981) (171)
- Expression of human apolipoprotein B and assembly of lipoprotein(a) in transgenic mice. (1994) (165)
- Rhesus monkey apolipoprotein(a). Sequence, evolution, and sites of synthesis. (1989) (160)
- Antifibrinolytic activity of apolipoprotein(a) in vivo: Human apolipoprotein(a) transgenic mice are resistant to tissue plasminogen activator-mediated thrombolysis (1995) (156)
- Reconstitution of lipoprotein(a) by infusion of human low density lipoprotein into transgenic mice expressing human apolipoprotein(a). (1992) (154)
- Apolipoprotein(a) size heterogeneity is related to variable number of repeat sequences in its mRNA. (1990) (145)
- Cloning and expression of human lecithin-cholesterol acyltransferase cDNA. (1986) (136)
- A new polymorphism in the factor VIII gene for prenatal diagnosis of hemophilia A. (1986) (135)
- Interaction of recombinant apolipoprotein(a) and lipoprotein(a) with macrophages. (1991) (133)
- Large Scale Gene Expression Analysis of Cholesterol-loaded Macrophages* (2000) (132)
- Targeting gene expression to the vascular wall in transgenic mice using the murine preproendothelin-1 promoter. (1995) (130)
- Apolipoprotein(a) Gene Enhancer Resides within a LINE Element* (1998) (129)
- Localization of Human ATP-Binding Cassette Transporter 1 (ABC1) in Normal and Atherosclerotic Tissues (2001) (128)
- Apolipoprotein(a): expression and characterization of a recombinant form of the protein in mammalian cells. (1991) (127)
- Cloning and expression of the cDNA for human antithrom, bin III (1982) (126)
- Human lecithin-cholesterol acyltransferase gene: complete gene sequence and sites of expression. (1986) (124)
- Multiple RFLPs at the human cholesteryl ester transfer protein (CETP) locus. (1987) (115)
- C/T polymorphism in the 5' untranslated region of the apolipoprotein(a) gene introduces an upstream ATG and reduces in vitro translation. (1995) (105)
- Human apolipoprotein A-I prevents atherosclerosis associated with apolipoprotein[a] in transgenic mice. (1994) (105)
- Leukocyte and fibroblast interferon genes are located on human chromosome 9. (1981) (104)
- Lipoprotein(a) in heart disease. (1992) (97)
- Association of growth differentiation factor 11/8, putative anti-ageing factor, with cardiovascular outcomes and overall mortality in humans: analysis of the Heart and Soul and HUNT3 cohorts. (2015) (97)
- Cellular localization of apolipoprotein D and lecithin:cholesterol acyltransferase mRNA in rhesus monkey tissues by in situ hybridization. (1990) (96)
- Human apolipoprotein D gene: gene sequence, chromosome localization, and homology to the alpha 2u-globulin superfamily. (1987) (94)
- Liver X receptors α and β regulate renin expression in vivo (2005) (92)
- DNA sequence of two closely linked human leukocyte interferon genes. (1981) (90)
- Genetic linkage between lipoprotein(a) phenotype and a DNA polymorphism in the plasminogen gene. (1988) (86)
- Impairment of Collateral Formation in Lipoprotein(a) Transgenic Mice: Therapeutic Angiogenesis Induced by Human Hepatocyte Growth Factor Gene (2002) (85)
- Interaction of apolipoprotein(a) with apolipoprotein B-containing lipoproteins. (1991) (85)
- The structure and evolution of the human beta-globin gene family. (1980) (84)
- Human fibroblast interferon gene lacks introns. (1981) (81)
- Fibrinogen deficiency reduces vascular accumulation of apolipoprotein(a) and development of atherosclerosis in apolipoprotein(a) transgenic mice. (1998) (80)
- Defensin promotes the binding of lipoprotein(a) to vascular matrix. (1999) (79)
- The Recurring Evolution of Lipoprotein(a) (1995) (78)
- Modification of apolipoprotein(a) lysine binding site reduces atherosclerosis in transgenic mice. (1997) (76)
- Convergent evolution of apolipoprotein(a) in primates and hedgehog. (1997) (76)
- Identification of a missense mutation in the factor VIII gene of a mild hemophiliac. (1986) (76)
- Cloning and mRNA tissue distribution of rabbit cholesteryl ester transfer protein. (1988) (71)
- Phosphatidylcholine Hydrolysis Is Required for Pancreatic Cholesterol Esterase- and Phospholipase A2-facilitated Cholesterol Uptake into Intestinal Caco-2 Cells* (1997) (70)
- Liver X receptors alpha and beta regulate renin expression in vivo. (2005) (64)
- High-content affinity-based proteomics: unlocking protein biomarker discovery (2010) (63)
- Lipoprotein(a) vascular accumulation in mice. In vivo analysis of the role of lysine binding sites using recombinant adenovirus. (1997) (63)
- Oxidized Low Density Lipoprotein Exposure Alters the Transcriptional Response of Macrophages to Inflammatory Stimulus* (2001) (62)
- DNA sequence of a major human leukocyte interferon gene. (1981) (61)
- The gene-size DNA molecules in Oxytricha. (1978) (60)
- Two polymorphisms in the human lipoprotein lipase (LPL) gene. (1987) (60)
- Apolipoprotein(a) gene transcription is regulated by liver-enriched trans-acting factor hepatocyte nuclear factor 1 alpha. (1994) (58)
- Cloning and expression of human tissue factor cDNA. (1987) (58)
- The isolation and characterization of linked delta- and beta-globin genes from a cloned library of human DNA. (1978) (56)
- Clustering of leukocyte and fibroblast interferon genes of human chromosome 9. (1982) (55)
- Feedback Mechanism of Focal Vascular Lesion Formation in Transgenic Apolipoprotein(a) Mice* (1996) (55)
- Molecular genetics of human serum albumin: restriction enzyme fragment length polymorphisms and analbuminemia. (1983) (52)
- High-level lipoprotein [a] expression in transgenic mice: evidence for oxidized phospholipids in lipoprotein [a] but not in low density lipoproteins. (2005) (50)
- Cloning and expression of the cDNA for human antithrombin III. (1982) (50)
- Lipoprotein(a) and atherogenesis. (1994) (49)
- Vascular interactions of lipoprotein (a). (1994) (48)
- “Variability gene” effect of cholesteryl ester transfer protein (CETP) genes (1989) (45)
- The apolipoprotein(a) gene resides on human chromosome 6q26–27, in close proximity to the homologous gene for plasminogen (1988) (45)
- Structure of human factor VIII. Nature (1984) (45)
- Polymorphisms in the apolipoprotein(a) gene and their relationship to allele size and plasma lipoprotein(a) concentration. (1997) (44)
- Mammalian cell transient expression of tissue factor for the production of antigen. (1990) (44)
- Physical properties of recombinant apolipoprotein(a) and its association with LDL to form an LP(a)-like complex. (1993) (42)
- Assembly of lipoprotein (a) in transgenic rabbits expressing human apolipoprotein (a). (1999) (42)
- Effects of estrus cycle, ovariectomy, and treatment with estrogen, tamoxifen, and progesterone on apolipoprotein(a) gene expression in transgenic mice. (1997) (41)
- Estrogen Modulation of Apolipoprotein(a) Expression (1999) (41)
- The human apolipoprotein(a)/plasminogen gene cluster contains a novel homologue transcribed in liver. (1994) (37)
- Molecular cloning and characterization of the human beta-like globin gene cluster. (1980) (37)
- ANTENATAL DIAGNOSIS AND CARRIER DETECTION OF HAEMOPHILIA A USING FACTOR VIII GENE PROBE (1985) (36)
- Functional analysis of the chimpanzee and human apo(a) promoter sequences: identification of sequence variations responsible for elevated transcriptional activity in chimpanzee. (2001) (34)
- The nucleotide sequence of the human beta-globin gene. (1980) (34)
- Assignment of the human gene for cholesteryl ester transfer protein to chromosome 16q12-16q21. (1987) (33)
- Novel therapeutic strategy for atherosclerosis: ribozyme oligonucleotides against apolipoprotein(a) selectively inhibit apolipoprotein(a) but not plasminogen gene expression. (1998) (33)
- Detection of hemophilia A carriers using intragenic factor VIII:C DNA polymorphisms. (1987) (29)
- The organization of repetitive sequences in mammalian globin gene clusters. (1981) (28)
- Spontaneous atherosclerosis in the proximal aorta of LPA transgenic mice on a normal diet. (2002) (28)
- The molecular genetics of hemophilia: Blood clotting factors VIII and IX (1985) (28)
- Determination of Temporal Expression Patterns for Multiple Genes in the Rat Carotid Artery Injury Model (2000) (26)
- How often has Lp(a) evolved? (1996) (22)
- Greek (Aγ) variant of hereditary persistence of fetal haemoglobin: globin gene organization and studies of expression of fetal haemoglobins in clonal erythroid cultures (1982) (22)
- Regulation of the Expression of the Apolipoprotein(a) Gene: Evidence for a Regulatory Role of the 5′ Distal Apolipoprotein(a) Transcription Control Region Enhancer in Yeast Artificial Chromosome Transgenic Mice (2003) (21)
- The relationship of lipoprotein (a) to hemostasis (1993) (21)
- Carboxyterminal region of hybrid leukocyte interferons affects antiviral specificity. (1982) (21)
- Genetic influences on lipoprotein(a) concentration. (1993) (21)
- The molecular genetics of hemophilia. (1986) (20)
- Oxidized Low Density Lipoprotein Blocks Lipopolysaccharide-induced Interferon β Synthesis in Human Macrophages by Interfering with IRF3 Activation* (2004) (20)
- A quantitative immunoassay for the lysine-binding function of lipoprotein(a). Application to recombinant apo(a) and lipoprotein(a) in plasma. (1996) (15)
- Loss of a splice donor site at a 'skipped exon' in a gene homologous to apolipoprotein(a) leads to an mRNA encoding a protein consisting of a single kringle domain. (1995) (14)
- Characterization of the mouse pancreatic/mammary gland cholesterol esterase-encoding cDNA and gene. (1995) (13)
- Gene-sized DNA molecules of the Oxytricha macronucleus have the same terminal sequence. (1977) (13)
- Expression monitoring using cDNA microarrays. A general protocol. (2001) (12)
- Studies on the structure and function of the apolipoprotein(a) gene (1994) (11)
- Despite its homology to angiostatin apolipoprotein(a) does not affect angiogenesis. (1998) (11)
- Histopathology of arterial lesions in LPA transgenic mice on cholesterol-enriched chow. (2000) (10)
- Regulation of the expression of the apolipoprotein(a) gene : evidence for a regulatory role of the 5' distal ACR enhancer in YAC transgenic mice (2003) (10)
- Apolipoprotein(a): A Puzzling Evolutionary Story (1997) (8)
- Chapter 2 – Molecular Biology of Apolipoprotein(a) (1990) (8)
- The lysine‐binding function of Lp(a) (1997) (8)
- LOW LEVELS OF GROWTH DIFFERENTIATION FACTOR 11 AND HIGH LEVELS OF ITS INHIBITOR FOLLISTATIN-LIKE 3 ARE ASSOCIATED WITH ADVERSE CARDIOVASCULAR OUTCOMES IN HUMANS (2015) (6)
- Endothelium-dependent vasorelaxation in the aorta of transgenic mice expressing human apolipoprotein(a) or lipoprotein(a). (2000) (6)
- Restriction site polymorphism at the LPA (Lp(a) apoliprotein; apoliprotein(a)) locus (1990) (5)
- The apolipoprotein(a) gene: characterization of 5' flanking regions and expression in transgenic mice. (1994) (5)
- Multiple RFLPs at the human apolipoprotein D (APOD) locus. (1987) (4)
- Abstract 14794: Stratification of Cardiovascular Risk Using an Unbiased Proteomic Approach (2012) (4)
- Characterization of the human factor VIII gene. 1984. (1992) (4)
- High-level lipoprotein [a] expression in transgenic mice: Published, JLR Papers in Press, January 16, 2005. DOI 10.1194/jlr.M400467-JLR200evidence for oxidized phospholipids in lipoprotein [a] but not in low density lipoproteins (2005) (4)
- Cloned factor VIII and the molecular genetics of hemophilia. (1986) (3)
- Electron-microscopic and hydrodynamic characterization of recombinant apolipoprotein (a) and its association with LDL. (1994) (3)
- Transgenic rats expressing human apolipoprotein(a). (1997) (2)
- THE HUMAN LEUKOCYTE INTERFERON GENE FAMILY: STRUCTURE AND EXPRESSION IN MAMMALIAN CELLS (1981) (2)
- Apolipoprotein(A) increases neointimal formation following carotid artery balloon injury in transgenic rats (1999) (1)
- The cloning of factor VIII and the genetics of hemophilia A. (1986) (1)
- 1.W08.4 Function and evolution of Lp(a) (1997) (1)
- SYNTHESIS OF HUMAN INTERFERONS AND ANALOGS IN HETEROLOGOUS CELLS (1982) (1)
- 1.W08.1 Lp(a) and endothelium: A feedback loop in atherosclerosis (1997) (1)
- Tu-W23:2 Can LXR, a transcriptional regulator of lipid metabolism, succeed as an HDL drug target? (2006) (0)
- Modulation of In Vivo Fibrinolysis by Apolipoprotein(A) Expression in Transgenic Mice (1996) (0)
- Transgenic Rabbits: A Novel Model for the Study of Atherosclerosis (2002) (0)
- Apo(a) Expression in Transgenic Mice a (1994) (0)
- Characterization of Linked Human Globin Genes by Molecular Cloning Procedures (1981) (0)
- Dna encoding variant of human serum albumin (1996) (0)
- Lawrence Berkeley National Laboratory Recent Work Title Regulation of the expression of the apolipoprotein ( a ) gene : Evidence for a regulatory role of the 5 ' distal ACR enhancer in YAC transgenic mice Permalink (2003) (0)
- Cloning and expression of the cDNA for human antithrombin mI (0)
- Apolipoprotein(a) Increases Neointimal Formation following Vascular Injury in Transgenic Rats (1999) (0)
- Production of human serum albumin by microorganism (1990) (0)
- Molecular genetics of human serum albumin : Restriction enzyme fragment length polymorphisms and analbuminemia ( human chromosome 4 markers / DNA variants / alloalbuminemia / prenatal diagnosis ) (1999) (0)
- Sequence and analysis of the chimpanzee apo(a) promoter (2001) (0)
- APPLICATION OF DNA ANALYSIS TO DETERMINE CARRIER STATUS (CS) OF HEMOPHILIA (1987) (0)
- 2.P.154 Lack of impaired endothelium-dependent vasorelaxation in aortas isolated from transgenic mice expressing human apolipoprotein(a) (1997) (0)
- United States Patent ( 19 ) Capon et al . 54 PREPARATION OF FUNCTIONAL HUMAN FACTOR VIN MAMMALIAN CELLS USING METHOTREXATE BASED SELECTION (2017) (0)
- Functional Analysis of the Chimpanzee and Humanapo(a) Promoter Sequences (2001) (0)
- cAMP regulates apolipoprotein-mediated cholesterol efflux by induction of expression of the tangier protein ABC1 (2000) (0)
- Composes developpant abca-1 (2001) (0)
- Apolipoprotein (a) and a Novel Apolipoprotein (a) Homologue are Expressed in Human Tumours (1995) (0)
- The Role of Lp(a) in Atherosclerosis (1991) (0)
- THE LINKAGE ARRANGEMENT OF MAMMALIAN β-LIKE GLOBIN GENES (1979) (0)
- Abstract: 1047 THE DISCOVERY OF GENES LINKED TO LIPID METABOLISM AND ATHEROSCLEROSIS (2009) (0)
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