Reinhold Penner
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Reinhold Pennercomputer-science Degrees
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Computational Linguistics
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Machine Learning
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Computer Science
Reinhold Penner's Degrees
- PhD Computer Science Stanford University
- Masters Computer Science University of California, Berkeley
- Bachelors Computer Science University of California, Berkeley
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(Suggest an Edit or Addition)Reinhold Penner's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Depletion of intracellular calcium stores activates a calcium current in mast cells (1992) (1758)
- Store depletion and calcium influx. (1997) (1492)
- CRACM1 Is a Plasma Membrane Protein Essential for Store-Operated Ca2+ Entry (2006) (1311)
- LTRPC7 is a Mg·ATP-regulated divalent cation channel required for cell viability (2001) (872)
- ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology (2001) (856)
- Calcium release‐activated calcium current in rat mast cells. (1993) (758)
- Regulation of Vertebrate Cellular Mg2+ Homeostasis by TRPM7 (2003) (692)
- TRPM4 Is a Ca2+-Activated Nonselective Cation Channel Mediating Cell Membrane Depolarization (2002) (652)
- A unified nomenclature for the superfamily of TRP cation channels. (2002) (603)
- Amplification of CRAC current by STIM1 and CRACM1 (Orai1) (2006) (599)
- CRACM1 Multimers Form the Ion-Selective Pore of the CRAC Channel (2006) (576)
- TRPM2-mediated Ca2+ influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration (2008) (519)
- TRPM7 Provides an Ion Channel Mechanism for Cellular Entry of Trace Metal Ions (2003) (480)
- Regulation of calcium influx by second messengers in rat mast cells (1988) (453)
- CRACM1, CRACM2, and CRACM3 Are Store-Operated Ca2+ Channels with Distinct Functional Properties (2007) (378)
- TRPM5 is a transient Ca2+-activated cation channel responding to rapid changes in [Ca2+]i (2003) (317)
- Cyclic ADP-ribose and hydrogen peroxide synergize with ADP-ribose in the activation of TRPM2 channels. (2005) (308)
- TRPM4 Regulates Calcium Oscillations After T Cell Activation (2004) (296)
- The TRPM ion channel subfamily: molecular, biophysical and functional features. (2004) (291)
- A GTP-dependent step in the activation mechanism of capacitative calcium influx. (1993) (265)
- TRPM2 Functions as a Lysosomal Ca2+-Release Channel in β Cells (2009) (264)
- The Store-Operated Calcium Current ICRAC: Nonlinear Activation by InsP3 and Dissociation from Calcium Release (1997) (243)
- TRPM2: a multifunctional ion channel for calcium signalling (2011) (238)
- CaT1 and the Calcium Release-activated Calcium Channel Manifest Distinct Pore Properties* (2001) (232)
- Transient Receptor Potential 1 Regulates Capacitative Ca2+ Entry and Ca2+ Release from Endoplasmic Reticulum in B Lymphocytes 〉 (2002) (206)
- 2‐Aminoethoxydiphenyl borate directly facilitates and indirectly inhibits STIM1‐dependent gating of CRAC channels (2008) (200)
- Dissociation of the store‐operated calcium current ICRAC and the Mg‐nucleotide‐regulated metal ion current MagNuM (2002) (190)
- TRPM7 Channel Is Regulated by Magnesium Nucleotides via its Kinase Domain (2006) (183)
- Receptor-mediated regulation of the TRPM7 channel through its endogenous protein kinase domain. (2004) (183)
- Nicotinic acid adenine dinucleotide phosphate and cyclic ADP‐ribose regulate TRPM2 channels in T lymphocytes (2006) (180)
- Intracellularly injected tetanus toxin inhibits exocytosis in bovine adrenal chromaffin cells (1986) (169)
- Depletion-activated calcium current is inhibited by protein kinase in RBL-2H3 cells. (1995) (169)
- STIM2 protein mediates distinct store‐dependent and store‐independent modes of CRAC channel activation (2008) (169)
- The role of calcium in stimulus-secretion coupling in excitable and non-excitable cells. (1988) (168)
- Second messenger‐activated calcium influx in rat peritoneal mast cells. (1989) (158)
- Ca2+ and Mn2+ influx through receptor-mediated activation of nonspecific cation channels in mast cells. (1993) (153)
- Calcium influx and its control by calcium release (1993) (148)
- A Pyrazole Derivative Potently Inhibits Lymphocyte Ca2+ Influx and Cytokine Production by Facilitating Transient Receptor Potential Melastatin 4 Channel Activity (2006) (147)
- TRPM4 controls insulin secretion in pancreatic β-cells (2007) (141)
- Dendritic cell maturation and chemotaxis is regulated by TRPM2‐mediated lysosomal Ca2+ release (2011) (127)
- Angiotensin II induces oscillations of intracellular calcium and blocks anomalous inward rectifying potassium current in mouse renal juxtaglomerular cells. (1989) (126)
- Discrimination of intracellular calcium store subcompartments using TRPV1 (transient receptor potential channel, vanilloid subfamily member 1) release channel activity. (2003) (123)
- Waixenicin A Inhibits Cell Proliferation through Magnesium-dependent Block of Transient Receptor Potential Melastatin 7 (TRPM7) Channels* (2011) (122)
- Calcium Release-activated Calcium Current (I CRAC) Is a Direct Target for Sphingosine* (1998) (121)
- Transfected cGMP-dependent protein kinase suppresses calcium transients by inhibition of inositol 1,4,5-trisphosphate production. (1993) (121)
- erratum: LTRPC7 is a Mg·ATP-regulated divalent cation channel required for cell viability (2001) (119)
- The actions of presynaptic snake toxins on membrane currents of mouse motor nerve terminals. (1987) (118)
- Non-specific effects of calcium entry antagonists in mast cells (1994) (116)
- Regulation of TRPM2 by Extra- and Intracellular Calcium (2007) (114)
- The Mg2+ and Mg(2+)-nucleotide-regulated channel-kinase TRPM7. (2007) (113)
- Synergistic regulation of endogenous TRPM2 channels by adenine dinucleotides in primary human neutrophils. (2008) (112)
- Functional expression of the calcium release channel from skeletal muscle ryanodine receptor cDNA (1989) (107)
- InsP4 facilitates store-operated calcium influx by inhibition of InsP3 5-phosphatase (2000) (105)
- Clofazimine Inhibits Human Kv1.3 Potassium Channel by Perturbing Calcium Oscillation in T Lymphocytes (2008) (102)
- TRPM4 controls insulin secretion in pancreatic beta-cells. (2007) (96)
- TRPM5 regulates glucose-stimulated insulin secretion (2010) (96)
- The patch-clamp technique in the study of secretion (1989) (92)
- Chloride conductance activated by external agonists and internal messengers in rat peritoneal mast cells. (1989) (90)
- Stimulation of Ca2+‐channel Orai1/STIM1 by serum‐and glucocorticoid‐inducible kinase 1 (SGK1) (2011) (89)
- ORAI3 silencing alters cell proliferation and cell cycle progression via c-myc pathway in breast cancer cells. (2013) (89)
- Two novel 2-aminoethyl diphenylborinate (2-APB) analogues differentially activate and inhibit store-operated Ca(2+) entry via STIM proteins. (2010) (89)
- A single lysine in the N-terminal region of store-operated channels is critical for STIM1-mediated gating (2010) (89)
- Multiple signaling pathways control stimulus-secretion coupling in rat peritoneal mast cells. (1988) (84)
- A Practical Guide to Patch Clamping (1995) (84)
- The TRPM7 channel kinase regulates store‐operated calcium entry (2017) (82)
- Cell cycle-dependent regulation of store-operated I(CRAC) and Mg2+-nucleotide-regulated MagNuM (TRPM7) currents. (2007) (79)
- Presynaptic glycine receptors enhance transmitter release at a mammalian central synapse (75)
- The calcium‐permeable non‐selective cation channel TRPM2 is modulated by cellular acidification (2010) (75)
- The TRPM6 Kinase Domain Determines the Mg·ATP Sensitivity of TRPM7/M6 Heteromeric Ion Channels* (2014) (70)
- Activation of store-operated I(CRAC) by hydrogen peroxide. (2010) (69)
- β-Bungarotoxin inhibits a non-inactivating potassium current in guinea pig dorsal root ganglion neurones (1986) (67)
- TRPM 2 Functions as a Lysosomal Ca 2 +-Release Channel in b Cells (2009) (60)
- STIM2 drives Ca2+ oscillations through store‐operated Ca2+ entry caused by mild store depletion (2013) (58)
- Novel chloride conductance in the membrane of bovine chromaffin cells activated by intracellular GTP gamma S. (1991) (56)
- Near‐visible ultraviolet light induces a novel ubiquitous calcium‐permeable cation current in mammalian cell lines (1998) (53)
- Ion Channels and Calcium Signaling in Mast Cells a (1993) (52)
- Washout phenomena in dialyzed mast cells allow discrimination of different steps in stimulus-secretion coupling (1987) (52)
- Lipopolysaccharide‐induced down‐regulation of Ca2+ release‐activated Ca2+ currents (ICRAC) but not Ca2+‐activated TRPM4‐like currents (ICAN) in cultured mouse microglial cells (2008) (52)
- Secretory responses of rat peritoneal mast cells to high intracellular calcium (1988) (51)
- Regulation of endogenous and heterologous Ca²⁺ release-activated Ca²⁺ currents by pH. (2014) (49)
- Supplemental Data S 1 CRACM 1 , CRACM 2 , and CRACM 3 Are Store-Operated Ca 2 + Channels with Distinct Functional Properties (47)
- Two different presynaptic calcium currents in mouse motor nerve terminals (1986) (41)
- Activation of store‐operated calcium influx at resting InsP3 levels by sensitization of the InsP3 receptor in rat basophilic leukaemia cells. (1995) (39)
- The Role of TRPC1 in Modulating Cancer Progression (2020) (37)
- Absence of Ca2+ current facilitation in skeletal muscle of transgenic mice lacking the type 1 ryanodine receptor. (1996) (35)
- Human CNNM2 is not a Mg2+ transporter per se (2016) (33)
- TRPM7 kinase activity regulates murine mast cell degranulation (2016) (33)
- Differential effects of various secretagogues on quantal transmitter release from mouse motor nerve terminals treated with botulinum A and tetanus toxin (2004) (32)
- TRPM7 is regulated by halides through its kinase domain (2013) (32)
- N-Myc-induced up-regulation of TRPM6/TRPM7 channels promotes neuroblastoma cell proliferation (2014) (31)
- Acceleration of Membrane Recycling by Axotomy of Cultured Aplysia Neurons (1996) (30)
- Inhibition of TRPM7 suppresses cell proliferation of colon adenocarcinoma in vitro and induces hypomagnesemia in vivo without affecting azoxymethane-induced early colon cancer in mice (2017) (29)
- Membrane repolarization stops caffeine-induced Ca2+ release in skeletal muscle cells. (1994) (26)
- Distinct sites of action of clostridial neurotoxins revealed by double-poisoning of mouse motor nerve terminals (1987) (26)
- Multiple mechanisms of manganese-induced quenching of fura-2 fluorescence in rat mast cells (1993) (26)
- Excessive repolarization‐dependent calcium currents induced by strong depolarizations in rat skeletal myoballs. (1995) (24)
- Store-Operated Calcium Entry: A Tough Nut to CRAC (2004) (24)
- Dendrotoxin: a selective blocker of a non-inactivating potassium current in guinea-pig dorsal root ganglion neurones (1986) (23)
- Ca2+-induced Ca2+ Release in Chinese Hamster Ovary (CHO) Cells Co-expressing Dihydropyridine and Ryanodine Receptors (1997) (23)
- Development and Optimization of a High-Throughput Bioassay for TRPM7 Ion Channel Inhibitors (2010) (22)
- Lack of direct evidence for a functional role of voltage-operated calcium channels in juxtaglomerular cells (1990) (21)
- IP(3) receptor subtype-dependent activation of store-operated calcium entry through I(CRAC). (2009) (19)
- Stimulation of Ca 2-channel Orai 1 / STIM 1 by serum-and glucocorticoid-inducible kinase 1 ( SGK 1 ) (2011) (19)
- Silent calcium channels generate excessive tail currents and facilitation of calcium currents in rat skeletal myoballs. (1996) (19)
- Scalaradial Is a Potent Inhibitor of Transient Receptor Potential Melastatin 2 (TRPM2) Ion Channels. (2017) (19)
- Emerging roles of TRPM channels. (2004) (18)
- TheMg 2 + andMg 2 +-Nucleotide-Regulated Channel-Kinase TRPM 7 (2006) (18)
- State‐dependent blocking mechanism of Kv1.3 channels by the antimycobacterial drug clofazimine (2015) (17)
- Regulation of store-operated calcium currents in mast cells. (1996) (17)
- The coiled-coil domain of zebrafish TRPM7 regulates Mg·nucleotide sensitivity (2016) (17)
- Areca nut extracts mobilize calcium and release pro-inflammatory cytokines from various immune cells (2018) (16)
- Effects of angiotensin II on intracellular calcium and electrical function of mouse renal juxtaglomerular cells. (1990) (16)
- Pharmacology of JNJ‐28583113: A novel TRPM2 antagonist (2019) (15)
- Guanosine 5'-[beta-thio]triphosphate selectively activates calcium signaling in mast cells. (1991) (15)
- Action of botulinum A toxin and tetanus toxin on synaptic transmission. (1984) (15)
- TRPM2 channels are not required for acute airway inflammation in OVA-induced severe allergic asthma in mice (2013) (14)
- TRPM7 contributes to progressive nephropathy (2020) (12)
- TRPM 5 regulates glucose-stimulated insulin secretion (2010) (11)
- Characterization of the Ca2+ current in isolated terminals of crustacean peptidergic neurons. (1996) (11)
- Stimulus-secretion coupling in mast cells. (1989) (10)
- with Distinct Functional Properties (2007) (10)
- Small-Conductance Ca2+-Activated Potassium Type 2 Channels Regulate the Formation of Contextual Fear Memory (2015) (9)
- ORAI 3 silencing alters cell proliferation and cell cycle progression via c-myc pathway in breast cancer cells (2013) (9)
- The TRPM7 kinase limits receptor-induced calcium release by regulating heterotrimeric G-proteins (2018) (7)
- Differential modulation of voltage-dependent Ca2+ currents by EGTA and BAPTA in bovine adrenal chromaffin cells (1999) (6)
- ctivation of store-operated ICRAC by hydrogen peroxide (2010) (6)
- D-6-Deoxy-myo-inositol 1,3,4,5-tetrakisphosphate, a mimic of d-myo-inositol 1,3,4,5-tetrakisphosphate: biological activity and pH-dependent conformational properties. (2004) (5)
- Role of ICRAC in the Regulation of Secretion (1999) (4)
- A pyrazole derivative potently inhibits lymphocyte Ca 2+ influx and cytokine production by facilitating TRPM4 channel activity (2006) (4)
- WAIXENICIN A INHIBITS CELL PROLIFERATION THROUGH MAGNESIUM-DEPENDENT BLOCK OF TRPM 7 (2011) (4)
- Erratum to: Inhibition of TRPM7 suppresses cell proliferation of colon adenocarcinoma in vitro and induces hypomagnesemia in vivo without affecting azoxymethane-induced early colon cancer in mice (2017) (4)
- Depletion-activated Ca current is inactivated by protein kinase C (1995) (4)
- Novel calcium current activated by depletion of intracellular calcium stores. (1992) (4)
- Transient Receptor Potential C 1/4/5 Is a Determinant of MTI-101 Induced Calcium Influx and Cell Death in Multiple Myeloma (2021) (3)
- Do chromaffin cells have capacitative Ca2+ influx? (1996) (3)
- Acidic Cannabinoids Suppress Proinflammatory Cytokine Release by Blocking Store-operated Calcium Entry (2022) (3)
- Slow calcium-induced calcium release (CICR) in Chinese hamster ovary (CHO) cells expressing skeletal ryanodine receptor (RyR) and chimaeric dihydropyridine receptor (DHPR). (1996) (2)
- Washout Phenomena in Dialyzed Allow Discrimination of Different Stimulus-Secretion Coupling (1987) (2)
- The FASEB JournalResearch Communication Stimulation of Ca 2 -channel Orai1/STIM1 by serum- and glucocorticoid-inducible kinase 1 (SGK1) (2012) (2)
- entry caused by mild store depletion (2013) (1)
- Inhibition of TRPM7 suppresses cell proliferation of colon adenocarcinoma in vitro and induces hypomagnesemia in vivo without affecting azoxymethane-induced early colon cancer in mice (2017) (1)
- [The importance of calcium for secretion in excitable and non-excitable cells]. (1989) (1)
- Contents, Vol. 94, 1991 (1991) (1)
- Depletion-activated calcium current is inhibited by protein kinase in RBL-2 H 3 cells ( Ca 2 + release-activated Ca 2 + current / protein kinase / fura-2 / patch clamp ) (2005) (1)
- TRPM7 kinase domain confers magnesium sensitivity to G-protein regulated mast cell degranulation (86.14) (2010) (1)
- Sex-dependent effect of aging on calcium signaling and expression of TRPM2 and CRAC channels in human neutrophils. (2022) (1)
- Calcium release activated calcium current(ICRAC) in monexcitable cells. (1993) (1)
- Multiple signaling pathways control stimulus-secreti (1988) (1)
- CRAC Channel Inhibitors (2017) (0)
- Ultraviolet light activates a calcium-permeable non-selective cation current. (1997) (0)
- Erratum to: Inhibition of TRPM7 suppresses cell proliferation of colon adenocarcinoma in vitro and induces hypomagnesemia in vivo without affecting azoxymethane-induced early colon cancer in mice (2017) (0)
- Sensing and repletion mechanisms of calcium stores (2018) (0)
- Human CNNM2 is not a Mg2+ transporter per se (2016) (0)
- TRPM7 is regulated by halides through its kinase domain (2013) (0)
- TRPM2 channels are not required for acute airway inflammation in OVA-induced severe allergic asthma in mice (2013) (0)
- P 3 receptor subtype-dependent activation of store-operated calcium entry hrough (2009) (0)
- Pharmacology of a novel TRPM2 antagonist, JNJ‐28583113 (2016) (0)
- DIFFERENT COMPONENTS OF ABDOMINAL FAT ARE SIGNIFICANTLY DIFFERENTIALLY CORRELATED WITH INFLAMMATION AND VASCULAR DISEASE MODIFYING MOLECULES IN A COHORT OF HIV PATIENTS WITH INCREASED CARDIOVASCULAR RISK: IMPACT OF ABDOMINAL OBESITY IN PATIENTS WITH HIV (2023) (0)
- Exogenous sphingosine inhibits I-CRAC. (1997) (0)
- Abstract A116: University of Guam/University of Hawaii Cancer Center Partnership leads areca (betel) nut research in the Pacific Islands (2020) (0)
- currents of mouse motor nerve terminals. The actions of presynaptic snake toxins on membrane (2007) (0)
- and cytokine production by facilitating TRPM4 channel activity Ryuichi Takezawa, Henrique Cheng, Andreas Beck, Jun Ishikawa, Pierre Launay, Hirokazu (2006) (0)
- Regulation of free intracellular calcium in non-excitable cells. (1988) (0)
- Dendritic cells: function (PP-024) (2010) (0)
- Transient Receptor Potential Melastatin 2 (TRPM2) is a Calcium Release Channel Essential for Chemotaxis of Dendritic Cells (44.17) (2010) (0)
- Tail currents through R-type calcium channels in chromaffin cells (1994) (0)
- The TRPM7 kinase limits receptor-induced calcium release by regulating heterotrimeric G-proteins (2018) (0)
- Manganese entry pathways in rat mast cells. (1993) (0)
- TRPM7 contributes to progressive nephropathy (2020) (0)
- Pharmacological profile of calcium entry in mast cells (1994) (0)
- Areca nut extracts mobilize calcium and release pro-inflammatory cytokines from various immune cells (2018) (0)
- Biographical Sketch of Dr. Alec H. Sehon (1991) (0)
- Letters to Nature 590 (0)
- TRPM2 functions as Ca2+ release channel in beta-cells (2010) (0)
- A GTP analogue induces calcium release but not secretion in rat mast cells. (1991) (0)
- The apparent voltage-dependent inactivation of cardiac L-type calcium channels seems to be a voltage-dependent block relieved upon repolarization following strong depolarizations. (1997) (0)
- Transient Receptor Potential Melastatin 2 (TRPM2) is a Calcium Release Channel Essential for Chemotaxis of Dendritic Cells (2010) (0)
- Abstract of the 68th Meeting (Spring Meeting) 6–9 March 1990, Heidelberg (1990) (0)
- IP4 facilitates store-operated calcium influx by inhibition of IP3 5-phosphatase (2001) (0)
- STIM2 drives calcium oscillations through store-operated calcium entry caused by mild store depletion (P1160) (2013) (0)
- DETECTABILITY OF CIRCULATING NOVEL SMALL LEUCIN-RICH-REPEAT PROTEIN (SLRP) PODOCAN IS STRONGLY AND SELECTIVELY ASSOCIATED WITH INCREASED LEVELS OF IL-10 IN PERSONS LIVING WITH HIV (PLWH) WITH INCREASED CARDIOVASCULAR RISK (2023) (0)
- 314 Penner , Pusch and Neher with a GTP-binding protein as a mediator between receptor and the lipase ( Kennedy (2005) (0)
- CBGA ameliorates inflammation and fibrosis in nephropathy. (2023) (0)
- DYNAMIC CHANGES OF SURROGATE MARKERS OF ATHEROSCLEROTIC DISEASE SUCH AS CAROTID-INTIMA-MEDIA-THICKNESS (CIMT) AND CORONARY ARTERY CALCIUM SCORE (CAC) ARE DIFFERENTIALLY CORRELATED WITH BIOMARKERS IN A COHORT OF HIV PATIENTS WITH INCREASED CARDIOVASCULAR RISK (2023) (0)
- Ultraviolet light induces cytoplasmic calcium increase by activation of a calcium-permeable non-selective cation current. (1997) (0)
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