R. Sanders Williams

R. Sanders Williams's AcademicInfluence.com Rankings

R. Sanders Williams

Medical

#646

World Rank

#863

Historical Rank

Cardiology

#69

World Rank

#70

Historical Rank

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Why Is R. Sanders Williams Influential?

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According to Wikipedia, Robert Sanders "Sandy" Williams is the former President of the Gladstone Institutes in San Francisco, as well as Professor of Medicine at the University of California, San Francisco, with which Gladstone is affiliated. Prior to joining Gladstone, he was the Dean of the Duke University School of Medicine from 2001 to 2007.

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R. Sanders Williams's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

A calcineurin-dependent transcriptional pathway controls skeletal muscle fiber type. (1998) (1040)
Regulation of Mitochondrial Biogenesis in Skeletal Muscle by CaMK (2002) (692)
Exercise Stimulates Pgc-1α Transcription in Skeletal Muscle through Activation of the p38 MAPK Pathway* (2005) (682)
Regulation of Stroke Volume during Submaximal and Maximal Upright Exercise in Normal Man (1986) (509)
Stimulation of Slow Skeletal Muscle Fiber Gene Expression by Calcineurin in Vivo * (2000) (451)
Introduction of foreign genes into tissues of living mice by DNA-coated microprojectiles. (1991) (429)
A Protein Encoded within the Down Syndrome Critical Region Is Enriched in Striated Muscles and Inhibits Calcineurin Signaling* (2000) (420)
Cardiovascular and behavioral effects of aerobic exercise training in healthy older men and women. (1989) (409)
E2F3 activity is regulated during the cell cycle and is required for the induction of S phase. (1998) (393)
Independent Signals Control Expression of the Calcineurin Inhibitory Proteins MCIP1 and MCIP2 in Striated Muscles (2000) (349)
STIM1 signalling controls store-operated calcium entry required for development and contractile function in skeletal muscle (2008) (343)
Myocyte-enriched calcineurin-interacting protein, MCIP1, inhibits cardiac hypertrophy in vivo (2001) (309)
Remodeling muscles with calcineurin (2000) (285)
Cdc6 is regulated by E2F and is essential for DNA replication in mammalian cells. (1998) (277)
Cardioprotective effects of 70-kDa heat shock protein in transgenic mice. (1996) (271)
Regulation of nuclear and mitochondrial gene expression by contractile activity in skeletal muscle. (1986) (268)
Mice without myoglobin (1998) (266)
Mitochondrial gene expression in mammalian striated muscle. Evidence that variation in gene dosage is the major regulatory event. (1986) (265)
Highly Coordinated Gene Regulation in Mouse Skeletal Muscle Regeneration* 210 (2003) (263)
Dual roles of modulatory calcineurin-interacting protein 1 in cardiac hypertrophy (2003) (227)
Exercise responses before and after physical conditioning in patients with severely depressed left ventricular function. (1982) (215)
The role of modulatory calcineurin-interacting proteins in calcineurin signaling. (2003) (191)
Activation of the heat shock transcription factor by hypoxia in mammalian cells. (1990) (173)
Myogenic stem cell function is impaired in mice lacking the forkhead/winged helix protein MNF. (2000) (166)
Functional heterogeneity of mammalian TATA-box sequences revealed by interaction with a cell-specific enhancer (1990) (165)
Repeat polymorphisms within gene regions: phenotypic and evolutionary implications. (2000) (165)
Human heat shock protein 70 (hsp70) protects murine cells from injury during metabolic stress. (1993) (165)
A human protein related to yeast Cdc6p. (1997) (163)
Adaptation of skeletal muscle to increased contractile activity. Expression nuclear genes encoding mitochondrial proteins. (1987) (161)
Persistent expression of MNF identifies myogenic stem cells in postnatal muscles. (1997) (153)
Multiple Domains of MCIP1 Contribute to Inhibition of Calcineurin Activity* (2002) (150)
Physical conditioning augments the fibrinolytic response to venous occlusion in healthy adults. (1980) (149)
Skeletal muscle beta-adrenergic receptors: variations due to fiber type and training. (1984) (144)
Comparison of high- and low-intensity exercise training early after acute myocardial infarction. (1988) (141)
Cardiac-Specific LIM Protein FHL2 Modifies the Hypertrophic Response to &bgr;-Adrenergic Stimulation (2001) (139)
PR48, a Novel Regulatory Subunit of Protein Phosphatase 2A, Interacts with Cdc6 and Modulates DNA Replication in Human Cells (2000) (138)
Skeletal muscle adaptation in response to voluntary running in Ca2+/calmodulin-dependent protein kinase IV-deficient mice. (2004) (135)
Targeted Inhibition of Calcineurin in Pressure-overload Cardiac Hypertrophy (2002) (133)
Physiologic basis for the age-related decline in aerobic work capacity. (1986) (129)
Induction of stress proteins in cultured myogenic cells. Molecular signals for the activation of heat shock transcription factor during ischemia. (1992) (128)
Subcellular partitioning of MRP RNA assessed by ultrastructural and biochemical analysis (1994) (125)
Electrical Stimulation of Neonatal Cardiac Myocytes Activates the NFAT3 and GATA4 Pathways and Up-regulates the Adenylosuccinate Synthetase 1 Gene* (2000) (124)
Protective responses in the ischemic myocardium. (2000) (118)
MCIP1 Overexpression Suppresses Left Ventricular Remodeling and Sustains Cardiac Function After Myocardial Infarction (2004) (114)
Feasibility and benefits of exercise training in patients on maintenance dialysis. (1984) (108)
Continuous contractile activity induces fiber type specific expression of HSP70 in skeletal muscle. (1996) (105)
Differential Expression of Mitochondrial DNA Replication Factors in Mammalian Tissues* (1998) (104)
Nerve Activity-dependent Modulation of Calcineurin Signaling in Adult Fast and Slow Skeletal Muscle Fibers* (2001) (100)
TRPC3 channels confer cellular memory of recent neuromuscular activity. (2004) (99)
Protein-coated poly(L-lactic acid) fibers provide a substrate for differentiation of human skeletal muscle cells. (2004) (97)
Functional and molecular adaptations in skeletal muscle of myoglobin-mutant mice. (2001) (96)
Myocyte nuclear factor, a novel winged-helix transcription factor under both developmental and neural regulation in striated myocytes (1994) (94)
Mice Lacking Homer 1 Exhibit a Skeletal Myopathy Characterized by Abnormal Transient Receptor Potential Channel Activity (2008) (93)
Effects of Experimental Diabetes on Adrenergic and Cholinergic Receptors of Rat Myocardium (1983) (92)
Alpha‐Adrenergic Receptors in Rat Myocardium: Identification by Binding of [3H]Dihydroergocryptine (1978) (90)
Adaptive Mechanisms That Preserve Cardiac Function in Mice Without Myoglobin (2001) (90)
Increased expression of fibroblast growth factors in a rabbit skeletal muscle model of exercise conditioning. (1990) (83)
Induction of immediate-early genes by angiotensin II and endothelin-1 in adult rat cardiomyocytes (1993) (82)
Transcriptional Regulation of Cardiac Progenitor Cell Populations (2004) (79)
Effects of Exercise Training on Ventricular Function in Patients with Recent Myocardial Infarction (1982) (79)
Thyroid Hormone Regulation of Alpha‐Adrenergic Receptors: Studies in Rat Myocardium (1979) (78)
A 40-kilodalton protein binds specifically to an upstream sequence element essential for muscle-specific transcription of the human myoglobin promoter (1992) (74)
Effects of inhibition of mitochondrial protein synthesis in skeletal muscle. (1987) (74)
Selectivity of dobutamine for adrenergic receptor subtypes: in vitro analysis by radioligand binding. (1981) (69)
Resident stem cells are not required for exercise-induced fiber-type switching and angiogenesis but are necessary for activity-dependent muscle growth. (2006) (69)
Mechanical stretch inhibits myoblast-to-adipocyte differentiation through Wnt signaling. (2005) (68)
Transient regulation of c-fos, αB-crystallin, and hsp70 in muscle during recovery from contractile activity. (1998) (67)
The winged-helix/forkhead protein myocyte nuclear factor β (MNF-β) forms a co-repressor complex with mammalian Sin3B (2000) (67)
Biphasic induction of immediate early gene expression accompanies activity-dependent angiogenesis and myofiber remodeling of rabbit skeletal muscle. (1994) (66)
Regulation of Gene Expression in Skeletal Muscle by Contractile Activity (2011) (66)
Mitochondrial DNA structure and expression in specialized subtypes of mammalian striated muscle (1990) (64)
Nuclear responses to depletion of mitochondrial DNA in human cells. (1995) (63)
Homer modulates NFAT-dependent signaling during muscle differentiation. (2005) (61)
Synergistic interactions between heterologous upstream activation elements and specific TATA sequences in a muscle-specific promoter (1995) (61)
Transient expression of a winged-helix protein, MNF-beta, during myogenesis (1997) (59)
Transgenic animals in integrative biology: approaches and interpretations of outcome. (2000) (59)
Autonomic mechanisms of training bradycardia: beta-adrenergic receptors in humans. (1981) (59)
Effect of exercise on cation transport in human red cells. (1985) (58)
Postnatal development and plasticity of specialized muscle fiber characteristics in the hindlimb. (1996) (57)
Differentiation of hemodynamic, humoral and metabolic responses to beta 1- and beta 2-adrenergic stimulation in man using atenolol and propranolol. (1983) (54)
Physical conditioning and membrane receptors for cardioregulatory hormones. (1980) (54)
Effect of skeletal muscle fiber type on the pressor response evoked by static contraction in rabbits. (1995) (53)
Alterations in Slow‐Twitch Muscle Phenotype in Transgenic Mice Overexpressing the Ca2+ Buffering Protein Parvalbumin (2003) (53)
Regulatory Elements Governing Transcription in Specialized Myofiber Subtypes* (2001) (52)
Beta-Adrenergic receptors of human lymphocytes are unaltered by hyperthyroidism. (1979) (51)
Subtype specificity of alpha-adrenergic receptors in rat heart. (1981) (49)
Conditional Expression of SV40 T-antigen in Mouse Cardiomyocytes Facilitates an Inducible Switch from Proliferation to Differentiation* 210 (2003) (49)
Pretranslational regulation of myoglobin gene expression. (1987) (48)
Collaborative interactions between MEF‐2 and Sp1 in muscle‐specific gene regulation (1998) (46)
Effects of physical conditioning on left ventricular ejection fraction in patients with coronary artery disease. (1984) (45)
The winged-helix/forkhead protein myocyte nuclear factor beta (MNF-beta) forms a co-repressor complex with mammalian sin3B. (2000) (44)
Exercise-induced functional desensitization of canine cardiac beta-adrenergic receptors. (1987) (43)
Cholesterol metabolism in non-obese women--Failure of physical conditioning to alter levels of high density lipoprotein cholesterol. (1979) (43)
Mitochondrial biogenesis in striated muscles: rapid induction of citrate synthase mRNA by nerve stimulation. (1991) (42)
Identification of a muscle-specific enhancer within the 5'-flanking region of the human myoglobin gene. (1989) (42)
Apoptosis and heart failure. (1999) (42)
Tetramerization and Single-stranded DNA Binding Properties of Native and Mutated Forms of Murine Mitochondrial Single-stranded DNA-binding Proteins* (1997) (42)
Bcl3 Interacts Cooperatively with Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) Coactivator 1α To Coactivate Nuclear Receptors Estrogen-Related Receptor α and PPARα (2009) (41)
Transient regulation of c-fos, alpha B-crystallin, and hsp70 in muscle during recovery from contractile activity. (1998) (39)
Canaries in the coal mine: mitochondrial DNA and vascular injury from reactive oxygen species. (2000) (38)
Gradients of transgene expression directed by the human myoglobin promoter in the developing mouse heart. (1993) (37)
Hemodynamic and metabolic responses to exercise after adrenoceptor blockade in humans. (1984) (36)
Sequence elements required for transcriptional activity of the human myoglobin promoter in intact myocardium. (1993) (35)
Effects of beta 1-selective and nonselective beta-adrenoceptor blockade during exercise conditioning in healthy adults. (1984) (35)
The Basis for the Increase in Factor VIII Procoagulant Activity During Exercise (1983) (33)
Effects of endurance training on cholinergic and adrenergic receptors of rat heart. (1984) (32)
Life without myoglobin (2000) (32)
Another surprise from the mitochondrial genome. (2002) (32)
Interactions between sustained contractile activity and beta-adrenergic receptors in regulation of gene expression in skeletal muscles. (1989) (31)
Transcriptional analysis of mouse skeletal myofiber diversity and adaptation to endurance exercise (2004) (27)
Plasticity of myocytes and capillaries: a possible coordinating role for VEGF. (2004) (27)
Age-dependent changes in expression of alpha 1-adrenergic receptors in rat myocardium. (1986) (26)
Calcium-dependent gene regulation in myocyte hypertrophy and remodeling. (2002) (25)
Developmental regulation of cytochrome oxidase subunit VIa isoforms in cardiac and skeletal muscle. (1996) (24)
Cardiac involvement in mitochondrial diseases, and vice versa. (1995) (23)
Enhanced receptor-cyclase coupling and augmented catecholamine-stimulated lipolysis in exercising rats. (1982) (23)
20 Expression and Function of Stress Proteins in the Ischemic Heart (1994) (22)
Left bundle branch block: angiographic segmental wall motion abnormalities. (1979) (21)
Cloning and Characterization of Three New Murine Genes Encoding Short Homologues of RNase P RNA (*) (1995) (19)
Cell cycle control in the terminally differentiated myocyte. A platform for myocardial repair? (1998) (18)
11 – The Effects of Thyroid Hormone on Adrenergic Receptors (1983) (18)
Regulation of GLUT4 expression in denervated skeletal muscle. (2009) (17)
Role of receptor mechanisms in the adaptive response to habitual exercise. (1985) (16)
Heat shock protein 47 : a chaperone for the fibrous cap? (2000) (15)
Exercise and the Heart, 2nd ed. (1986) (15)
Beta 1-selective and non-selective beta-adrenoceptor blockade, anaerobic threshold and respiratory gas exchange during exercise. (1985) (15)
RNA subunit of mitochondrial RNA-processing enzyme is induced by contractile activity in striated muscle. (1993) (14)
Beta adrenergic blockade with propranolol and atenolol in the exercising dog: evidence for beta 2 adrenoceptors in the sinoatrial node. (1987) (14)
Activity-induced adaptations in skeletal muscles of iron-deficient rabbits. (1988) (14)
MCIP 1 Overexpression Suppresses Left Ventricular Remodeling and Sustains Cardiac Function After Myocardial Infarction (2004) (14)
Calcineurin signaling in human cardiac hypertrophy. (2002) (14)
Genetic Mechanisms That Determine Oxidative Capacity of Striated Muscles: Control of Gene Transcription (1990) (13)
Muscle-specific activation of Ca2+/calmodulin-dependent protein kinase IV increases whole-body insulin action in mice (2014) (13)
A CDC6 Protein-binding Peptide Selected Using a Bacterial Two-hybrid-like System Is a Cell Cycle Inhibitor* (2000) (12)
Hemodynamic and metabolic responses to exercise after alpha 1-, beta 1-, and nonselective beta-adrenoceptor blockade in man. (1984) (11)
Differentiation of Hemodynamic, Humoral and Metabolic Responses to β1‐ and β2‐adrenergic Stimulation in Man Using Atenolol and Propranolol (1983) (10)
Human gene therapy — of tortises and hares (1995) (10)
The end of the beginning. Gene transfer into the vessel wall. (1992) (10)
A deadly game of musical chairs: survival of cells transplanted for myocardial repair. (2001) (9)
Stress proteins and cardiovascular disease. (1991) (9)
Boosting cardiac contractility with genes. (1995) (9)
Biological effects of physical activity (1989) (8)
The genetics of cardiovascular disease: from genotype to phenotype (2004) (8)
Exercise training of patients with ventricular dysfunction and heart failure. (1985) (8)
Exercise and Health: Can Biotechnology Confer Similar Benefits? (2005) (7)
Prevention of Coronary Heart Disease—Practical Management of the Risk Factors (1984) (7)
Subtype Specificity of α‐Adrenergic Receptors in Rat Heart (1981) (6)
Book Review Heart Development Edited by Richard P. Harvey and Nadia Rosenthal. 530 pp., illustrated. San Diego, Calif., Academic Press, 1999. $159.95. 0-12-329860-1 (1999) (6)
Rapid Publication Induction of Stress Proteins in Cultured Myogenic Cells (6)
Biolistic transformation of animal tissue (2007) (5)
Paroxysmal hypotension associated with sympathetic withdrawal. A new disorder of autonomic vasomotor regulation. (1980) (3)
Intracellular Signals Mediating Contraction-Induced Changes in the Oxidative Capacity of Skeletal Muscle (1990) (3)
Alpha-Adrenergic Receptors in Rat Myocardium Identification by Binding of [ 3 H ] (2005) (3)
Physical conditioning in patients with severely depressed left ventricular function (1980) (3)
Southwestern Internal Medicine Conference: prospects for gene therapy of ischemic heart disease. (1993) (3)
American Heart Association National Research Awards. New programs for 1996. (1995) (3)
Heat shock proteins and ischemic injury to the myocardium. (1997) (3)
Molecular mechanisms of skeletal muscle adaptations to exercise. (1991) (2)
for Adrenergic Receptor Subtypes (1981) (2)
Molecular biology in cardiology: recent developments and opportunities for clinical applications. (1990) (2)
Cholesterol controversy--where do we go from here? 'Toward healthful diets' reevaluated. (1982) (2)
Skeletal Muscle Hypertrophy and Response to Training (2006) (1)
752 CHRONIC MOTOR NERVE STIMULATION INDUCES EXPRESSION OF CYTOSOLIC AND MITOCHONDRIAL HEAT SHOCK RNAS (1994) (1)
Vascular biology and invasive cardiology. The streams are beginning to merge. (1992) (1)
Exercise and Fibrinolysis (1983) (1)
INDUCTION OF FOS AND HSP70 RNA IN SKELETAL MUSCLE DURING RECOVERY FROM CONTRACTILE ACTIVITY.: 700 (1995) (1)
9: 30 a.m.: PSYCHOLOGICAL CHANGES ACCOMPANYING PHYSICAL EXERCISE: A CONTROLLED STUDY (1981) (1)
Expression, purification, and in vitro assays of mitochondrial single-stranded DNA-binding protein. (2002) (1)
DEVELOPMENTAL REGULATION OF MYOGLOBIN GENE EXPRESSION IN TRANSGENIC MICE (1998) (1)
Selectivity of Prenalterol for Adrenergic Receptor Subtypes: A Potential Mechanism of Inotropic Selectivity (1983) (1)
Sanders Williams Oxygen Species Canaries in the Coal Mine : Mitochondrial DNA and Vascular Injury From Reactive (2000) (0)
musclegene transcription in denervated skeletal Regulation of glucose transporters GLUT-4 and (2015) (0)
112: A RANDOMIZED TRIAL OF HIGH AND LOW INTENSITY EXERCISE TRAINING IN POST-MI PATIENTS (1987) (0)
Gli-1 Activation after Exercise : Evidence for a Sonic Hedgehog (Shh)-Mediated Signaling in Adult Skeletal Muscle (2003) (0)
Transformation of animal skin cells with the help of particles (1990) (0)
Differential Gene Expression in Muscle (1999) (0)
77 Genetic control of muscle growth by the growth-suppressor gene, p53 (1993) (0)
Exercise and Health: The Evidence and the Implications (1982) (0)
DISRUPTION OF ATP PRODUCTION INCREASES C-FOS EXPRESSION IN SKELETAL MUSCLE.: 701 (1995) (0)
Prospects for gene therapy of ischemic heart disease (1993) (0)
ALTERED CONTRACTILE FUNCTION IN SLOW-TWITCH MUSCLE FROM TRANSGENIC MICE OVEREXPRESSING PARVALBUMIN (1999) (0)
Abstract 954: Stim1/orai1 Signaling Controls Store Operated Calcium Entry Required For Signaling And Contractile Function In Smooth And Striated Muscle (2007) (0)
Book ReviewValvular Heart Disease (1987) (0)
Transformation of epidermal cells of animal tissues with the help of particles. (1990) (0)
Failure of Physical Conditioning to Alter Levels of High Density Lipoprotein Cholesterol (1979) (0)
Paroxysmal Hypotension Associated with Sympathetic Withdrawal (2005) (0)
CORONARY ARTERY DISEASE Effects of physical conditioning on left ventricular ejection fraction in patients with coronary artery disease (0)
Physical conditioning reduces epinephrine-induced platelet aggregation following myocardial infarction (1980) (0)
Essentials of Cardiac Physical Diagnosis (1988) (0)
Exercise function and biochemical properties of β‐adrenergic receptors of canine heart (1991) (0)
SIGNAL TRANSDUCTION IN STRIATED MUSCLE: METABOLIC, CONTRACTILE, AND BLOOD FLOW CONTROL.: 2 (1995) (0)
growth are necessary for activity-dependent muscle exercise-induced fiber-type switching and angiogenesis Resident stem cells are not required for (2009) (0)
Pharmac . ( 1985 ) , 19 , 13-20 r 3 l-selective and non-selective 1-adrenoceptor blockade , anaerobic threshold and respiratory gas exchange during exercise (2006) (0)

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