Raymond Victor Rajotte
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(Suggest an Edit or Addition)Raymond Victor Rajotte's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. (2000) (3210)
- Clinical outcomes and insulin secretion after islet transplantation with the Edmonton protocol. (2001) (859)
- Successful islet transplantation: continued insulin reserve provides long-term glycemic control. (2002) (725)
- Long-term survival of neonatal porcine islets in nonhuman primates by targeting costimulation pathways (2006) (461)
- Islet isolation assessment in man and large animals (1990) (422)
- Large scale isolation, growth, and function of porcine neonatal islet cells. (1996) (351)
- Glucose-dependent insulin release from genetically engineered K cells. (2000) (302)
- Variables in organ donors that affect the recovery of human islets of Langerhans. (1996) (297)
- Granzyme B: a natural born killer (2003) (275)
- Cotransplantation of Allogeneic Islets With Allogeneic Testicular Cell Aggregates Allows Long-Term Graft Survival Without Systemic Immunosuppression (1997) (235)
- Transfection of human pancreatic islets with an anti-apoptotic gene (bcl-2) protects beta-cells from cytokine-induced destruction. (1999) (223)
- Islet graft assessment in the Edmonton Protocol: implications for predicting long-term clinical outcome. (2004) (221)
- Glutaraldehyde-Fixed Bioprosthetic Heart Valve Conduits Calcify and Fail From Xenograft Rejection (2006) (200)
- Human pancreatic islet beta-cell destruction by cytokines involves oxygen free radicals and aldehyde production. (1996) (187)
- Cytotoxic effects of cytokines on human pancreatic islet cells in monolayer culture. (1990) (182)
- Differential Expression of GAD65 and GAD67 in Human, Rat, and Mouse Pancreatic Islets (1993) (178)
- Expansion of mesenchymal stem cells from human pancreatic ductal epithelium (2006) (173)
- Metformin, but not leptin, regulates AMP-activated protein kinase in pancreatic islets: impact on glucose-stimulated insulin secretion. (2004) (168)
- Transcript Expression Data from Human Islets Links Regulatory Signals from Genome-Wide Association Studies for Type 2 Diabetes and Glycemic Traits to Their Downstream Effectors (2015) (159)
- Critical Mass of Purified Islets That Induce Normoglycemia After Implantation Into Dogs (1988) (146)
- CD40‐Specific Costimulation Blockade Enhances Neonatal Porcine Islet Survival in Nonhuman Primates (2011) (145)
- Intraductal collagenase delivery into the human pancreas using syringe loading or controlled perfusion. (1998) (145)
- Performance of subcutaneously implanted needle-type glucose sensors employing a novel trilayer coating. (1993) (143)
- Basal expression of cyclooxygenase-2 and nuclear factor-interleukin 6 are dominant and coordinately regulated by interleukin 1 in the pancreatic islet. (1998) (142)
- Portal venous pressure changes after sequential clinical islet transplantation (2002) (139)
- Islet Xenotransplantation Using Gal‐Deficient Neonatal Donors Improves Engraftment and Function (2011) (138)
- Testicular sertoli cells protect islet beta-cells from autoimmune destruction in NOD mice by a transforming growth factor-beta1-dependent mechanism. (2000) (136)
- The Portal Immunosuppressive Storm: Relevance to Islet Transplantation? (2005) (135)
- Combination therapy with sirolimus and interleukin-2 prevents spontaneous and recurrent autoimmune diabetes in NOD mice. (2002) (132)
- Survival and Metabolic Function of Syngeneic Rat Islet Grafts Transplanted in the Omental Pouch (2003) (131)
- Human islet transplantation from pancreases with prolonged cold ischemia using additional preservation by the two-layer (UW solution/perfluorochemical) cold-storage method (2002) (131)
- Human pancreatic islet beta-cell destruction by cytokines is independent of nitric oxide production. (1994) (120)
- Percutaneous transhepatic pancreatic islet cell transplantation in type 1 diabetes mellitus: radiologic aspects. (2003) (120)
- Beta-cell destruction in NOD mice correlates with Fas (CD95) expression on beta-cells and proinflammatory cytokine expression in islets. (1999) (119)
- The role of CD4+ helper T cells in the destruction of microencapsulated islet xenografts in nod mice. (1990) (119)
- XIAP overexpression in human islets prevents early posttransplant apoptosis and reduces the islet mass needed to treat diabetes. (2005) (111)
- In vitro and in vivo performance and lifetime of perfluorinated ionomer-coated glucose sensors after high-temperature curing. (1994) (107)
- Decellularization reduces the immune response to aortic valve allografts in the rat. (2005) (99)
- Long-term follow-up after transplantation of insulin-producing pancreatic islets into patients with Type 1 (insulin-dependent) diabetes mellitus (2004) (99)
- Development of an ectopic site for islet transplantation, using biodegradable scaffolds. (2005) (97)
- Human pancreas preservation prior to islet isolation. Cold ischemic tolerance. (1995) (97)
- In vitro and in vivo expression of Galalpha-(1,3)Gal on porcine islet cells is age dependent. (2003) (97)
- Portal vein thrombosis after transplantation of partially purified pancreatic islets in a combined human liver/islet allograft. (1995) (89)
- SURVIVAL AND FUNCTION OF PURIFIED ISLETS IN THE OMENTAL POUCH SITE OF OUTBRED DOGS (1993) (86)
- Prevention of Recurrence of IDDM in Islet-Transplanted Diabetic NOD Mice by Adjuvant Immunotherapy (1992) (85)
- Peroxynitrite Is a Mediator of Cytokine-Induced Destruction of Human Pancreatic Islet β Cells (2001) (85)
- Preliminary in vivo biocompatibility studies on perfluorosulphonic acid polymer membranes for biosensor applications. (1991) (84)
- Intraductal Collagenase Delivery into the Human Pancreas Using Syringe Loading or Controlled Perfusion (1999) (84)
- COMBINED THERAPY WITH INTERLEUKIN‐4 AND INTERLEUKIN‐10 INHIBITS AUTOIMMUNE DIABETES RECURRENCE IN SYNGENEIC ISLET‐TRANSPLANTED NONOBESE DIABETIC MICE ANALYSIS OF CYTOKINE MRNA EXPRESSION IN THE GRAFT (1995) (83)
- SERINE-PROTEASE INHIBITION DURING ISLET ISOLATION INCREASES ISLET YIELD FROM HUMAN PANCREASES WITH PROLONGED ISCHEMIA1 (2001) (83)
- Studies of the isolation and viability of human islets of Langerhans. (1988) (79)
- Viability studies on frozen--thawed rat islets of Langerhans. (1977) (77)
- Research-Focused Isolation of Human Islets From Donors With and Without Diabetes at the Alberta Diabetes Institute IsletCore. (2016) (77)
- Insulin Resistance and Impaired Glucose Tolerance in the Atherosclerosis‐Prone LA/N Corpulent Rat (1987) (76)
- Neonatal Porcine Islets Exhibit Natural Resistance to Hypoxia-Induced Apoptosis (2006) (76)
- Effect of core pancreas temperature during cadaveric procurement on human islet isolation and functional viability1 (2002) (73)
- Normoglycaemia after transplantation of freshly isolated and cryopreserved pancreatic islets in Type 1 (insulin-dependent) diabetes mellitus (2004) (73)
- Improved survival of biolistically transfected mouse islet allografts expressing CTLA4-Ig or soluble Fas ligand. (1998) (73)
- Alternative Immunomodulatory Strategies for Xenotransplantation: CD40/154 Pathway‐Sparing Regimens Promote Xenograft Survival (2012) (72)
- CONTINUED FUNCTION OF PANCREATIC ISLETS AFTER TRANSPLANTATION IN TYPE I DIABETES (1989) (71)
- Immunoprotection of rat islet xenografts by cotransplantation with sertoli cells and a single injection of antilymphocyte serum1 (2003) (70)
- Normoglycemia after Reflux of Islet-containing Pancreatic Fragments into the Splenic Vascular Bed in Dogs (1983) (68)
- PROLONGATION OF CANINE PANCREATIC ISLET ALLOGRAFT SURVIVAL WITH COMBINED RAPAMYCIN AND CYCLOSPORINE THERAPY AT LOW DOSES: RAPAMYCIN EFFICACY IS BLOOD LEVEL RELATED1 (1993) (67)
- Rat heart fatty acid-binding protein content is increased in experimental diabetes. (1994) (67)
- Pancreatic islet banking: the transplantation of frozen-thawed rat islets transported between centers. (1981) (67)
- Improved survival of microencapsulated islets during in vitro culture and enhanced metabolic function following transplantation (2004) (66)
- Revelation of Specificity of 64K Autoantibodies in IDDM Serums by High-Resolution 2-D Gel Electrophoresis: Unambiguous Identification of 64K Target Antigen (1989) (66)
- Transplantation of cryopreserved and fresh rat islets and canine pancreatic fragments: comparison of cryopreservation protocols. (1983) (65)
- Streptozotocin-induced diabetes in rats is associated with impaired metabolic availability of vitamin A (retinol) (1996) (65)
- The efficacy and toxicity of rapamycin in murine islet transplantation. In vitro and in vivo studies. (1993) (65)
- Current status of islet cell transplantation. (2003) (65)
- A physiological level of rhubarb fiber increases proglucagon gene expression and modulates intestinal glucose uptake in rats. (1997) (64)
- T cell activation and anergy to islet cell antigen in type I diabetes. (1995) (62)
- Identification of a Novel Human Granzyme B Inhibitor Secreted by Cultured Sertoli Cells1 (2006) (62)
- Expression of CTLA4-Ig by biolistically transfected mouse islets promotes islet allograft survival. (1997) (62)
- Testicular Sertoli cells exert both protective and destructive effects on syngeneic islet grafts in non-obese diabetic mice (2000) (60)
- Reversal of diabetes in pancreatectomized pigs after transplantation of neonatal porcine islets. (2005) (59)
- A Primitive Enantiornithine Bird and the Origin of Feathers (2012) (59)
- Expression of Gal alpha(1,3)gal on neonatal porcine islet beta-cells and susceptibility to human antibody/complement lysis. (1998) (56)
- Long‐term survival of neonatal porcine Sertoli cells in non‐immunosuppressed rats (2003) (55)
- CTLA4-Ig prolongs survival of microencapsulated neonatal porcine islet xenografts in diabetic NOD mice. (1997) (53)
- Heterogenous expression of nestin in human pancreatic tissue precludes its use as an islet precursor marker. (2004) (52)
- NOVEL APPROACHES TOWARD EARLY DIAGNOSIS OF ISLET ALLOGRAFT REJECTION1 (2001) (52)
- Microencapsulation of neonatal porcine islets: protection from human antibody/complement-mediated cytolysis in vitro and long-term reversal of diabetes in nude mice. (2000) (51)
- Long-term survival of intratesticular porcine islets in nonimmunosuppressed beagles (2003) (50)
- Immune mechanisms associated with the rejection of encapsulated neonatal porcine islet xenografts (2006) (49)
- Stem cell-based approaches to solving the problem of tissue supply for islet transplantation in type 1 diabetes. (2004) (47)
- Interleukin-4 or interleukin-10 expressed from adenovirus-transduced syngeneic islet grafts fails to prevent beta cell destruction in diabetic NOD mice. (1997) (46)
- Harnessing the Immunomodulatory Properties of Sertoli Cells to Enable Xenotransplantation in Type I Diabetes (2003) (46)
- Islet Cryopreservation Using Intracellular Preservation Solutions (2001) (45)
- Isolation of viable islets of Langerhans from collagenase-perfused canine and human pancreata. (1987) (45)
- Sertoli Cell Line Lacks the Immunoprotective Properties Associated with Primary Sertoli Cells (2008) (44)
- Human pancreatic islet cell specific 38 kilodalton autoantigen identified by cytomegalovirus-induced monoclonal islet cell autoantibody (1990) (44)
- Normoglycemia after implantation of purified islet cells in dogs. (1988) (44)
- Novel approaches to cryopreservation of human pancreatic islets. (2001) (43)
- The degree of phylogenetic disparity of islet grafts dictates the reliance on indirect CD4 T-cell antigen recognition for rejection. (2003) (43)
- Development of an in vivo model to study testicular morphogenesis. (2002) (43)
- A biocompatible enzyme electrode for continuous in vivo glucose monitoring in whole blood (1990) (42)
- Both CD4+ and CD8+ T-Cells in Syngeneic Islet Grafts in NOD Mice Produce Interferon-γ During β-Cell Destruction (1996) (42)
- Islet Auto‐Transplantation into an Omental or Splenic Site Results in a Normal Beta Cell but Abnormal Alpha Cell Response to Mild Non‐Insulin‐Induced Hypoglycemia (2005) (41)
- Human islet function following 20 years of cryogenic biobanking (2015) (41)
- HIGH YIELD OF RODENT ISLETS WITH INTRADUCTAL COLLAGENASE AND STATIONARY DIGESTION-A COMPARISON WITH STANDARD TECHNIQUE. (1996) (41)
- Prolongation of Islet Xenograft Survival by Cryopreservation (1987) (41)
- Short-Term Administrations of a Combination of Anti–LFA-1 and Anti-CD154 Monoclonal Antibodies Induce Tolerance to Neonatal Porcine Islet Xenografts in Mice (2010) (40)
- Survival of frozen-thawed fetal rat pancreases as a function of the permeation of dimethylsulfoxide and glycerol, warming rate, and fetal age. (1977) (40)
- Critical mass of islets that function after implantation in a large mammalian. (1990) (40)
- BCG immunotherapy prevents recurrence of diabetes in islet grafts transplanted into spontaneously diabetic NOD mice. (1994) (39)
- Portal vein immunosuppressant levels and islet graft toxicity. (1998) (38)
- Defining optimal immunosuppression for islet transplantation based on reduced diabetogenicity in canine islet autografts (2002) (38)
- THE EFFECT OF CRYOPRESERVATION ON THE SURVIVAL AND MHC ANTIGEN EXPRESSION OF MURINE ISLET ALLOGRAFTS (1993) (38)
- Osmotic behavior and transport properties of human islets in a dimethyl sulfoxide solution. (1997) (38)
- Neonatal Porcine Sertoli Cells Inhibit Human Natural Antibody-Mediated Lysis1 (2005) (37)
- Genetically engineered Sertoli cells are able to survive allogeneic transplantation (2004) (37)
- TNF-alpha down-regulates type 1 cytokines and prolongs survival of syngeneic islet grafts in nonobese diabetic mice. (1997) (36)
- Islet Cryopreservation Protocols (1999) (36)
- PROLONGED FUNCTION OF CANINE PANCREATIC FRAGMENTS AUTOTRANSPLANTED TO THE SPLEEN BY VENOUS REFLUX (1990) (35)
- Increasing the dietary polyunsaturated fat content alters whole-body utilization of 16:0 and 10:0. (1995) (35)
- Comparison of Successful and Unsuccessful Islet/Sertoli Cell Cotransplant Grafts in Streptozotocin-Induced Diabetic Mice (2007) (35)
- Bacteremia due to Transplantation of Contaminated Cryopreserved Pancreatic Islets (1994) (35)
- Epithelial cells within the human pancreas do not coexpress mesenchymal antigens: epithelial–mesenchymal transition is an artifact of cell culture (2009) (33)
- Cryopreservation of insulin-producing tissue in rats and dogs (1984) (33)
- Permeability of the 17-day fetal rat pancreas to glycerol and dimethylsulfoxide. (1981) (32)
- Viable Purified Islets of Langerhans From Collagenase-Perfused Human Pancreas (1989) (31)
- Optimizing cryopreservation of isolated islets. (1989) (31)
- Diabetes Induces Rapid Suppression of Adaptive Immunity Followed by Homeostatic T‐cell Proliferation (2007) (30)
- Effect of dietary modification on the uptake of glucose, fatty acids, and alcohols in diabetic rats. (1983) (30)
- Analysis of cytokine mRNA expression in syngeneic islet grafts of NOD mice: interleukin 2 and interferon gamma mRNA expression correlate with graft rejection and interleukin 10 with graft survival (1994) (29)
- Mouse pancreatic islets are resistant to indoleamine 2,3 dioxygenase-induced general control nonderepressible-2 kinase stress pathway and maintain normal viability and function. (2009) (29)
- Successful biolistic transformation of mouse pancreatic islets while preserving cellular function. (1996) (29)
- Cloning of humna and rat p69 cDNA, a candidate autoimmune target in type 1 diabetes (1994) (29)
- First update of the International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes – Chapter 3: Porcine islet product manufacturing and release testing criteria (2016) (28)
- Enriched human pancreatic ductal cultures obtained from selective death of acinar cells express pancreatic and duodenal homeobox gene-1 age-dependently. (2004) (28)
- Effect of dietary modification on the enhanced uptake of cholesterol in diabetic rats. (1983) (28)
- Testicular Sertoli Cells Protect Islet-Cells From Autoimmune Destruction in NOD Mice by a Transforming Growth Factor-1 – Dependent Mechanism (2000) (28)
- Tissue banking of cryopreserved islets for clinical islet transplantation. (1994) (27)
- Reversal of diabetes in dogs by transplantation of pure cryopreserved islets. (1990) (26)
- Microbial surveillance of human islet isolation, in vitro culture, and cryopreservation. (1995) (26)
- Development of an Immunoprivileged Site to Prolong Islet Allograft Survival (2002) (26)
- Stem cells: a promising source of pancreatic islets for transplantation in type 1 diabetes. (2003) (26)
- Human pancreatic islet transplantation (1992) (26)
- Endothelium-dependent relaxation to acetylcholine in the aorta of streptozotocin induced diabetic-rat and the BB-diabetic rat. (1989) (25)
- Isolation and assessment of islet quality (2008) (25)
- Treatment of the enhanced intestinal uptake of glucose in diabetic rats with a polyunsaturated fatty acid diet. (1987) (25)
- Bioartificial organs and acceptable risk (1999) (25)
- Prolonged Survival of Microencapsulated Neonatal Porcine Islet Xenografts in Immune-Competent Mice without Antirejection Therapy (2008) (24)
- Cryopreservation of rat pancreatic islets: effect of ethylene glycol on islet function and cellular composition. (1997) (24)
- Cadaver pancreas recovery technique. Impact on islet recovery and in vitro function. (1994) (23)
- Combination of Anti-CD4 with Anti-LFA-1 and Anti-CD154 Monoclonal Antibodies Promotes Long-Term Survival and Function of Neonatal Porcine Islet Xenografts in Spontaneously Diabetic NOD Mice (2007) (23)
- Diets alter jejunal morphology and brush border membrane composition in streptozotocin-diabetic rats. (1987) (23)
- Endogenous immune response to glutamic acid decarboxylase (GAD67) in NOD mice is modulated by adjuvant immunotherapy. (1998) (22)
- The natural history of pure canine islet autografts in hepatic or splenic sites. (1989) (22)
- Survival and function of syngeneic rat islet grafts placed within the thymus versus under the kidney capsule. (1997) (22)
- Reinnervation of Isolated Islets of Langerhans Transplanted beneath the Kidney Capsule in the Rat (1994) (22)
- Comparison of sites for transplantation of canine pancreatic microfragments. (1989) (22)
- Long-Term Graft Function after Allogeneic Islet Transplantation (2007) (21)
- Protection of Porcine Islet Xenografts in Mice Using Sertoli Cells and Monoclonal Antibodies (2011) (21)
- Glucoregulatory response to moderate exercise in long-term islet cell autografted dogs. (1990) (20)
- Long-term normoglycemia in pancreatectomized dogs transplanted with frozen/thawed pancreatic islets. (1986) (20)
- Microencapsulated dog and rat islet xenografts into streptozotocin-diabetic and NOD mice. (1990) (20)
- Cyanidin-3-O-Glucoside Enhanced the Function of Syngeneic Mouse Islets Transplanted Under the Kidney Capsule or Into the Portal Vein (2015) (19)
- Markedly Reduced β-Cell Function Does Not Result in Insulin Resistance in Islet Autografted Dogs (1992) (19)
- Use of polyunsaturated fatty acid diet to treat the enhanced intestinal uptake of lipids in streptozotocin diabetic rats. (1988) (19)
- Polyunsaturated fat in the diet may improve intestinal function in patients with Crohn's disease. (1997) (19)
- Islet isolation from human pancreas stored in UW solution for 6 to 26 hours. (1990) (18)
- Anti-BSA antibodies do not cross-react with the 69-kDa islet cell autoantigen ICA69. (1998) (18)
- Cryopreservation purifies canine pancreatic microfragments. (1987) (18)
- Bioartificial organs II : technology, medicine, and materials (1999) (18)
- Development of an omental pouch site for islet transplantation. (1992) (18)
- Both CD4+ and CD8+ T-cells in syngeneic islet grafts in NOD mice produce interferon-gamma during beta-cell destruction. (1996) (17)
- Intrathymic transplantation of fresh and cryopreserved islets for the induction of a state of unresponsiveness in rats. (1996) (17)
- Cloning of human and rat p69 cDNA, a candidate autoimmune target in type 1 diabetes. (1994) (17)
- Effects of pre-cryopreservation culture on human islet recovery and in vitro function. (1994) (17)
- Natural human antibody‐mediated destruction of porcine neonatal islet cell grafts (1996) (17)
- The evaluation of solutions for pancreas preservation prior to islet isolation. (1990) (16)
- Effects of precryopreservation culture on survival of rat islets transplanted after slow cooling and rapid thawing. (1989) (16)
- Insulin Sensitivity and Glucose Effectiveness in Long-Term Islet-Autotransplanted Dogs (1989) (16)
- Risk for developing Type 1 (insulin-dependent) diabetes mellitus and the presence of islet 64K antibodies (1991) (15)
- Diabetogenic synergism in canine islet autografts from cyclosporine and steroids in combination. (1998) (15)
- Cryopreservation of microencapsulated canine islets. (1995) (15)
- Osmotic and Cryoprotectant Permeation Characteristics of Islet Cells Isolated from the Newborn Pig Pancreas (2001) (15)
- Comparison of automated and manual methods for islet isolation. (1990) (14)
- Monotherapy with Anti-LFA-1 Monoclonal Antibody Promotes Long-Term Survival of Rat Islet Xenografts (2008) (14)
- Transplantation of purified frozen/thawed canine pancreatic islet allografts with cyclosporine. (1991) (14)
- Effect of cryopreservation on the survival and function of murine islet isografts and allografts. (1998) (13)
- Long-term graft function after allogeneic islet transplantation. (2007) (13)
- Proglucagon messenger ribonucleic acid and intestinal glucose uptake are modulated by fermentable fiber and food intake in diabetic rats (2000) (13)
- Encapsulated islet iso-, allo-, and xenografts in diabetic NOD mice. (1995) (13)
- Isolation of purified large mammal and human islets of Langerhans. (1990) (13)
- Natural history of insulin independence after transplantation of multidonor cryopreserved pancreatic islets in type 1 diabetic humans. (1995) (12)
- Coencapsulation of allogeneic islets with allogeneic Sertoli cells prolongs graft survival without systemic immunosuppression. (1998) (12)
- Development of an automated computer-controlled islet isolation system. (1997) (12)
- Bulk cryopreservation of isolated islets of Langerhans. (1996) (12)
- Human ABO Blood Group Is Important in Survival and Function of Porcine Working Hearts (2003) (12)
- Histological studies on cultured canine heart valves recovered from −196 °C (1977) (12)
- Islet transplantation improves glucose oxidation and mechanical function in diabetic rat hearts. (1993) (12)
- Islet cryopreservation. (1990) (11)
- Improved intestinal form and function in diabetic rats fed long-term with a polyunsaturated fatty acid diet. (1989) (11)
- 35th Annual meeting of the European Association for the Study of Diabetes. Brussels, Belgium, 28 September-2 October, 1999. Abstracts. (1999) (11)
- Intestinal absorption of vitamin A in streptozotocin-induced diabetic rats. (1994) (11)
- Prevention of recurrence of insulin-dependent diabetes mellitus in islet cell-transplanted diabetic NOD mice using adjuvant therapy. (1992) (11)
- Applications of Microwave Thawing to the Recovery of Deep Frozen Cells and Organs:A Review* (1974) (11)
- Factors in cadaveric donors that affect recovery of human islets of Langerhans. (1995) (11)
- Pharmacokinetic Approach to the Estimation of Hepatic Removal of Insulin (1986) (11)
- Bulk Cryopreservation of Isolated Islets of Langerhans (1996) (11)
- Comparison of methods used for the removal of DMSO following cryopreservation and the development of an automated protocol. (1997) (11)
- OPTIMAL TEMPERATURE IN SHORT‐TERM HYPOTHERMIC PRESERVATION OF RAT PANCREAS (1991) (11)
- Comparison of Methods Used for the Removal of Dmso following Cryopreservation and the Development of an Automated Protocol (1997) (10)
- Microencapsulation of neonatal porcine islets: long-term reversal of diabetes in nude mice and in vitro protection from human complement mediated cytolysis. (1997) (10)
- Development of diagnostic markers for islet allograft rejection. (1998) (10)
- Osmotic and cryoprotectant permeation characteristics of islet cells isolated from the newborn pig pancreas. (2001) (10)
- Isolation and cryopreservation of human pancreatic islets. (1985) (10)
- SINGLE INJECTION OF INSULIN DELAYS THE RECURRENCE OF DIABETES IN SYNGENEIC ISLET-TRANSPLANTED DIABETIC NOD MICE 1 (2000) (10)
- Porcine islet cell antigens are recognized by xenoreactive natural human antibodies of both IgG and IgM subtypes. (1996) (10)
- Insulin and islet cell transplants: effects on diabetic rat cardiac myofibril ATPase. (1987) (10)
- Reversal of diabetes by transplantation of cryopreserved rat islets of Langerhans to the renal subcapsular space. (1987) (10)
- Survival and Function of Syngeneic Rat Islet Grafts Placed within the Thymus versus under the Kidney Capsule (1997) (9)
- A chronic conscious dog model for direct transhepatic studies in normal and pancreatic islet cell transplanted dogs. (1991) (9)
- Preliminary experiments on vitrification of isolated rat islets of Langerhans (1985) (9)
- Effect of diabetes on the function of transplanted human islets of Langerhans. (1990) (9)
- Immunization with streptozotocin-treated NOD mouse islets inhibits the onset of autoimmune diabetes in NOD mice. (2003) (9)
- Porcine Islet-Specific Tolerance Induced by the Combination of Anti-LFA-1 and Anti-CD154 mAbs is Dependent on PD-1 (2016) (9)
- Oral glucose tolerance and response to mixed meals in dogs bearing long-term transplanted islets of Langerhans. (1987) (9)
- Portal versus systemic insulin delivery in canine pancreatic islet cell transplantation. (1988) (9)
- Insulin secretion and substrate homeostasis in prolonged hypothermia in rats. (1988) (8)
- Collagenase digestion of canine pancreas by gentle automated dissociation in combination with ductal perfusion optimizes mass recovery of islets. (1992) (8)
- Transplantation of purified single-donor cryopreserved canine islet allografts with cyclosporine. (1991) (8)
- Long-term Survival Of Syngeneic Islet Grafts In Bcg-treated Diabetic Nod Mice Can Be Reversed By Cyclophosphamide (1995) (8)
- Reduced immunosuppression for in vitro cultured, pure canine islets transplanted from single donors. (1991) (8)
- Clinical response to feeding a high polyunsaturated fat diet in normal and diabetic rats. (1988) (8)
- Comparison of successful and unsuccessful islet/Sertoli cell cotransplant grafts in streptozotocin-induced diabetic mice. (2008) (8)
- Portal Vein Embolization with Radiolabeled Polyvinyl Alcohol Particles in a Swine Model: Hepatic Distribution and Implications for Pancreatic Islet Cell Transplantation (2009) (8)
- Humoral reaction to microencapsulated rat, canine, and porcine islet xenografts in spontaneously diabetic NOD mice. (1993) (8)
- Effect of Insulin Treatment or Zinc Supplementation on Vitamin A Status in Streptozotocin-Induced Diabetic Rats. (1995) (8)
- Pancreas preservation prior to islet isolation: evaluation of storage solutions in a rodent model. (1990) (8)
- Dietary fat saturation alters diabetic rat brush border membrane phospholipid fatty acid composition. (1990) (8)
- Isolation of islets of Langerhans following cold storage of human pancreas. (1987) (7)
- New site for islet transplantation in rats--liver-mesentery or liver-omental pouch. (1994) (7)
- Development of an Automated Computer-Controlled Islet Isolation System (1997) (7)
- Strain variation in vitamin A (retinol) status of streptozotocin-induced diabetic rats. (1996) (7)
- Rapamycin prolongs murine islet allograft survival. (1992) (7)
- Canine pancreatic fragment allotransplantation with cyclosporine A. (1985) (7)
- Microencapsulation enhances canine islet survival during long-term culture. (1995) (7)
- Expression of beta-galactosidase in mouse pancreatic islets by adenoviral-mediated gene transfer. (1995) (7)
- Pancreatic islet cell transplantation: past, present and future. (1988) (7)
- Cold ischemic tolerance of human pancreas: assessment of islet recovery and in vitro function. (1994) (7)
- Mass isolation of pure canine islets. (1989) (7)
- Viability studies on cryopreserved isolated canine islets of Langerhans. (1989) (7)
- The natural history of transplantation of insulin-producing pancreatic islets into type I diabetic patients. (1992) (7)
- Accuracy of C-peptide:insulin molar ratio as a measure of hepatic removal of insulin. (1987) (6)
- Low-temperature cryopreservation of BB rat embryos of spontaneously diabetic rats. (1983) (6)
- Could fewer islet cells be transplanted in type 1 diabetes? (2001) (6)
- Gal alpha(1,3)Gal expression on neonatal porcine islet cells and susceptibility to human antibody/complement lysis. (1998) (6)
- Development of a method for bulk cryopreservation of purified canine islets. (1994) (6)
- Prolongation of allograft survival of transfected islets expressing human CTLA4-Ig, human soluble Fas ligand or a combination of the two. (1998) (6)
- Bioartificial Organ Grafts: A View at the Beginning of the Third Millennium (2003) (6)
- Transplantation of microencapsulated syngeneic and xenogeneic (neonatal porcine) islets in nonobese diabetic mice. (1998) (6)
- Quantitative analysis of islet glutamic acid decarboxylase p64 autoantibodies in insulin-dependent diabetes mellitus. (1992) (6)
- Intrasplenic isografts of canine pancreatic islets: metabolic study. (1984) (6)
- Effect of pefabloc on islet isolation from cold preserved rat pancreas. (2002) (5)
- Pancreatic Islet Cell Transplantation: A new era in transplantation. (1992) (5)
- Recovery and in vivo function of canine islets cryopreserved in a freezer bag. (1995) (5)
- Effect of high/low dietary linoleic acid levels on the function and fatty acid composition of T-lymphocytes of normal and diabetic rats. (1988) (5)
- Dietary omega-3 fatty acids partially correct the enhanced in vivo uptake of glucose in diabetic rats. (1990) (5)
- Successful reversal of diabetes in nude mice by transplantation of microencapsulated porcine neonatal islet cell aggregates. (1995) (5)
- Effect of trypsin inhibitor on islet isolation from fresh and cold preserved rat pancreas. (2003) (4)
- A comparison of human islet purification with discontinuous density gradients of Ficoll prepared with Euro-Collins or medium 199 solution. (1992) (4)
- Microbial studies of a tissue bank of cryopreserved human islet cells. (1994) (4)
- Comparison of dextran and Ficoll density gradients for purification of canine islets. (1992) (4)
- Effect of dietary fat on diabetes-induced changes in liver microsomal fatty acid composition and glucose-6-phosphatase activity in rats (1991) (4)
- Prolongation of concordant islet xenografts with leflunomide. (1996) (4)
- Effect of diet on islet cell transplantation. (1987) (4)
- Prospective evaluation of two techniques for human pancreas recovery before islet isolation. (1994) (4)
- Multilayered Coatings of Perfluorinated Ionomer Membranes and Poly(phenylenediamine) for the Protection of Glucose Sensors In Vivo (1994) (4)
- Reassessment of the Vascularization of Renal Subcapsular Islet Grafts (2004) (4)
- Cryopreservation of Human Pancreatic Islets (2002) (4)
- Microencapsulation improves canine islet survival in vivo. (1995) (4)
- A Consensus Document based on the Pig‐to‐Man Islet Transplant Summit held in Stockholm, June 4–5, 2007 (2008) (4)
- Transplantation of single-donor purified canine islets to the spleen or renal subcapsular space with cyclosporine immunosuppression. (1989) (4)
- Moving towards clinical application (2008) (4)
- Microwave thawing of tissue culture cells. (1972) (4)
- Large-scale isolation of viable porcine neonatal islet cell (NIC) aggregates. (1995) (4)
- Impact of Lazaroid U74006F on ischemia and reperfusion injury of islets after transplantation in the rat. (1996) (4)
- Neonatal porcine islet xenografts in nonobese diabetic mice: effects on blood glucose and analysis of cytokines expressed in the islet grafts. (1998) (4)
- Studies of the isolation and transplantation of purified islets in adult humans. (1991) (4)
- Survival of electrical activity of deep frozen fetal mouse hearts after microwave thawing. (1974) (3)
- Cryopreservation of Pancreatic Islets (1989) (3)
- Fish oil modifies effect of high cholesterol diet on intestinal absorption in diabetic rats. (1993) (3)
- Failure of Neonatal B-Cell Tolerance Induction by ABO-Incompatible Kidney Grafts in Piglets (2013) (3)
- Human islet purification with discontinuous density gradients following cold storage of the pancreas. (1993) (3)
- Cryopreserved human fetal pancreas: a source of insulin-producing tissue? (1988) (3)
- Mass isolation of highly purified islets from the canine pancreas. (1991) (3)
- Long-term survival of syngeneic islet grafts in BCG-treated diabetic NOD mice can be reversed by cyclophosphamide. (1995) (3)
- Trophic stimulation of adult human islets in vitro. (1992) (3)
- INSULIN INDEPENDENCE AFTER SOLITARY ISLET TRANSPLANTATION IN TYPE 1 DIABETIC PATIENTS USING STEROID‐FREE IMMUNOSUPPRESSION.: Abstract# 1105 (2000) (3)
- The effect of hepatic insulin influx on insulin retention: comparison of net flux and per cent extraction as indices of hepatic insulin retention. (1985) (3)
- Transplantation of a known number of fresh and frozen-thawed rat islets (1981) (3)
- The Effect of Somatostatin on Insulin and Glucose Levels During Insulin Infusion in Anesthetized Dogs (1990) (3)
- Ability of transplanted frozen-thawed fetal rat pancreases to reverse experimentally induced diabetes☆ (1977) (3)
- Human anti-A and anti-B antibodies interact with alphaGal antibody affecting xenograft survival. (2004) (3)
- Survival and function of human islets subjected to gamma-radiation. (1994) (3)
- Frozen fetal and neonatal mouse cardiac reimplants for assessing cryoprotective agents. (1976) (3)
- Porcine Islet Xenotransplantation for the Treatment of Type 1 Diabetes (2011) (3)
- Isocaloric modification of dietary lipids influences intestinal brush border membrane composition in diabetic rats. (1991) (3)
- Critical factors in survival of a pig-human xenograft (2001) (2)
- OR.96. Long-Term Survival of Neonatal Porcine Islet Xenografts in Diabetic Non-Human Primates By Targeting Costimulation Pathways (2006) (2)
- Reversal of diabetes by transplantation of pure cryopreserved canine islets. (1990) (2)
- A comparison of canine renal and islet transplantation with cyclosporine: assessment of islet immunogenicity. (1989) (2)
- Improved function of islet grafts under steroid-free immunosuppression: will grafts work forever? Response to letter by Birkeland et al. (2002) (2)
- Immunosuppression and pancreatic islet transplantation. (1990) (2)
- Dietary lipid content influences the clinical and intestinal adaptive responses to islet transplantation in diabetic rats. (1992) (2)
- Adjuvant immunotherapy with Bacillus Calmette-Guerin prevents recurrence of diabetes in islet grafts transplanted into NOD mice. (1994) (2)
- Twenty-four-hour hypothermic storage of the canine pancreas before islet isolation. (1989) (2)
- Effect of Cryopreservation on the Survival and Function of Murine Islet Isografts and Allografts (1998) (2)
- CTLA4-Ig Prolongs Survival of Microencapsulated Neonatal Porcine Islet Xenografts in Diabetic Nod Mice (1997) (2)
- Effect of warming rate on slowly cooled isolated rat islets (1986) (2)
- Intraportal transplantation of cryopreserved human fetal pancreata. (1987) (2)
- Somatostatin increases hepatic insulin extraction. (1988) (2)
- Portal Vein Insulin Flux and Arterial Glucose Fluctuations in Response to an Oral Meal Test in Islet Cell‐Transplanted Dogs (1994) (2)
- Secondary Pathologic Conditions in Diabetes Mellitus and the Benefit of Improved Metabolic Control Achieved Through Pancreatic Islet Transplantation (1992) (2)
- Increased apoptosis in porcine cardiac xenografts perfused with human ABO plasma containing the anti-B antibody. (2004) (2)
- Transmission of Porcine Endogenous Retrovirus is not prevented by microencapsulation of porcine islets but is reduced with an intact immune system: 069 (2003) (1)
- Low-temperature preservation of embryos from diabetic rats (1981) (1)
- Prolonged function of intrasplenic canine pancreatic fragment autografts. (1989) (1)
- Cryomicroscopy of islets: an investigation of the parameters that govern the response to low temperature preservation. (1987) (1)
- Culture of Microencapsulated Neonatal Porcine Islets is Associated with an Increased Proportion of [Beta] Cells/Cellular Insulin Content and Elevated Expression of IDX-1 (1999) (1)
- Optimization of removal of cryoprotectant from frozen-thawed islets. (1997) (1)
- MRI monitoring of transplanted neonatal porcine islets labeled with polyvinylpyrrolidone‐coated superparamagnetic iron oxide nanoparticles in a mouse model (2021) (1)
- Effect of diet fat on liver nuclear membrane phospholipid fatty acid composition and insulin binding after islet transplantation (1995) (1)
- Successful cryopreservation of rat islets using ethylene glycol. (1997) (1)
- In-situ crosslinking thermoreversible polymers for cell entrapment. (2004) (1)
- Low temperature preservation of rat and dog islets (1982) (1)
- Microencapsulation of neonatal porcine islets. Long term reversal of diabetes in nude mice and in vitro protection from human complement mediated cytolysis. (1996) (1)
- Hepatic insulin retention depends on influx in both diabetic and normal dogs. (1985) (1)
- Insulin and islet cell transplant--effect on intestinal uptake of lipids. (1984) (1)
- Islet transplantation. (1997) (1)
- Letter to the Editor (2004) (1)
- Histological studies on cultured canine heart valves recovered from -196 degrees C. (1977) (1)
- Islet recovery from rat pancreas is altered by procurement technique and flush solution. (1990) (1)
- Effect of precryopreservation tissue culture on the outcome of transplanted rat islets of Langerhans (1987) (1)
- Insulin and islet cell transplantation in streptozotocin-diabetic rats: effect on intestinal uptake of hexoses. (1985) (1)
- Effect of cryopreservation on islet recovery and in vivo function. (1995) (1)
- Stationary digestion after intraductal collagenase improves islet recovery in the rat. (1995) (1)
- 23 DIFFERENCES IN PORTAL AND SYSTEMIC BLOOD PHARMACOKINTICS AFTER ORAL DOSING OF IMMUNOSUPPRESSANTS (1997) (1)
- Low temperature preservation studies on organized mammalian tissues (1975) (0)
- Reduction of islet immunogenicity by cryopreservation (1987) (0)
- Induction of tolerance to neonatal porcine islet xenografts using a combination of anti-LFA-1 and anti-CD154 does not require CD4+ or CD8+ T cells. (2007) (0)
- Purification of pancreatic microfragments by cryopreservation (1986) (0)
- Inhibitor Secreted by Cultured Sertoli Cells Identification of a Novel Human Granzyme B (2006) (0)
- Pre-Treatment with Manganese Porphyrin Enhances the Function of Neonatal Pig Islet Transplants in Diabetic Mice.: Abstract# B3018 (2014) (0)
- Glucose and free fatty acid homeostasis during deep, long term hypothermia in the white rat: Role of insulin ☆ ☆☆ (1987) (0)
- Conditions for the induction of unresponsiveness to cryopreserved islet allografts with intrathymic islets. (1994) (0)
- STUDIES OF THE ISOLATION AND VIABILITY OF HUMAN ISLETS OF LANGERHANS1,2 (1988) (0)
- Reduced insulin response from transplanted islet cells impairs regulation of hepatic glucose output. (1994) (0)
- Epidermal Growth Factor And Gastrin Combination Therapy Stimulates In Vivo Neogenesis Of Human Islet ∃‐CELLS AND AN INCREASE IN FUNCTIONAL ∃‐CELL MASS: 0125 (2003) (0)
- Osmotic volume changes in isolated rat islets (1985) (0)
- Osmotic water movement in isolated human and rat islets of Langerhans (1986) (0)
- Measurement of osmotic volume changes in tissues (1986) (0)
- Xenotransplantation: An Overview (2004) (0)
- Reversal of diabetes in totally pancreatectomized pigs after allografting neonatal porcine islets: 029 (2003) (0)
- Cell Separation, Perfusion from Tissue, Organelle Fractionation (2012) (0)
- Long-term effects of manipulations of dietary omega-3 fatty acids on clinical control and in vitro uptake of glucose and lipids in diabetic rats. (1990) (0)
- Letter to the Editor (2004) (0)
- Sonde implantable, destinee a detecter le glucose (1994) (0)
- Dose dependence of bacillus Calmette-Guerin on the prevention of autoimmune diabetes in syngeneic islet transplantation. (1995) (0)
- Long-term survival of rat islet xenografts after anti-NK1.1 monoclonal antibody therapy. (2005) (0)
- Biolistic transformation of pancreatic islets. (1995) (0)
- Therapeutic Effects of Islets Isolated From Genetically Engineered Pigs Transgenic for hCD46 and hCD39 in Immune-Deficient Mice.: Abstract# D2862 (2014) (0)
- IS BLOOD GROUP ANTIGEN EXPRESSION ON VASCULAR ENDOTHELIUM REQUIRED FOR B CELL TOLERANCE INDUCTION FOLLOWING ABO-INCOMPATIBLE TRANSPLANT DURING IMMUNOLOGICAL IMMATURITY?: 1511 (2010) (0)
- In vitro and in vivo expression of Gal (cid:1) –(1,3)Gal on porcine islet cells is age dependent (2003) (0)
- NEONATAL PORCINE SERTOLI CELLS DO NOT EXPRESS GAL&mgr;(1,3)GAL AND ARE RESISTAN TO HUMAN ANTIBODY/COMPLEMENT MEDIATED LYSIS: 070 (2003) (0)
- COMBINATION OF ANTI-LFA-1 AND ANTI-CD154 MONOCLONAL ANTIBODIES INDUCES TISSUE-SPECIFIC TOLERANCE TO NEONATAL PORCINE ISLET XENOGRAFTS: 299 (2008) (0)
- Transplantation of frozen-thawed rat islets of Langerhans after sucrose versus step dilution (1980) (0)
- CREATION OF AN ECTOPIC SITE FOR ISLET TRANSPLANTATION: 024 (2003) (0)
- Yield, cell composition, and function of islets isolated from different ages of neonatal pigs (2022) (0)
- Islet Isolation and Cryopreservation in Rats and Dogs (1990) (0)
- Islet cryopreservation using intracellular preservation solutions. (2001) (0)
- Permeation kinetics of dimethylsulfoxide in isolated rat and human islets (1986) (0)
- 3.03 – Cell Separation, Perfusion from Tissue, Organelle Fractionation: A Comparison of the Methods Used for Porcine Islet Isolation for Transplantation as a Treatment for Type 1 Diabetes Mellitus (2012) (0)
- Preservation of pancreatic islets (1987) (0)
- IMMUNOGENICITY OF ISLETS ISOLATED FROM THREE AND SEVEN DAY-OLD NEWBORN PIGS: 2677 (2010) (0)
- Impact of donor and prolonged cold ischemia time of neonatal pig pancreas on neonatal pig islet transplant outcome (2020) (0)
- Long-Term Survival of Intra-Testicular Xenogeneic Islets Without Immunosuppression in a Large Animal Model. (1999) (0)
- Continuous microscopic observation of islets during CPA addition, freezing and thawing, and CPA removal (1987) (0)
- PROLONGED SURVIVAL OF MICROENCAPSULATED NEONATAL PORCINE ISLET XENOGRAFTS IN IMMUNE- COMPETENT MICE WITHOUT ANTI-REJECTION THERAPY –IN VITRO CO-CULTURE WITH BONE MARROW AND SERTOLI CELLS: 581 (2008) (0)
- Cryopreservtion of isolated islets (1985) (0)
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