Riccardo Vigneri
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Computer Science
Riccardo Vigneri's Degrees
- PhD Computer Science University of Milan
- Masters Computer Science University of Milan
- Bachelors Computer Science University of Milan
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(Suggest an Edit or Addition)Riccardo Vigneri's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Worldwide Increasing Incidence of Thyroid Cancer: Update on Epidemiology and Risk Factors (2013) (1080)
- Insulin receptor isoforms and insulin receptor/insulin-like growth factor receptor hybrids in physiology and disease. (2009) (937)
- Insulin Receptor Isoform A, a Newly Recognized, High-Affinity Insulin-Like Growth Factor II Receptor in Fetal and Cancer Cells (1999) (865)
- Cancer risk in patients with cold thyroid nodules: relevance of iodine intake, sex, age, and multinodularity. (1992) (505)
- Insulin/Insulin-like Growth Factor I Hybrid Receptors Have Different Biological Characteristics Depending on the Insulin Receptor Isoform Involved* (2002) (484)
- Overexpression of the c-MET/HGF receptor gene in human thyroid carcinomas. (1992) (332)
- Clinical behavior and outcome of papillary thyroid cancers smaller than 1.5 cm in diameter: study of 299 cases. (2004) (332)
- Elevated insulin receptor content in human breast cancer. (1990) (328)
- Diabetes and cancer. (2009) (309)
- Insulin receptor activation by IGF-II in breast cancers: evidence for a new autocrine/paracrine mechanism (1999) (293)
- Insulin and insulin-like growth factor-I (IGF-I) receptor overexpression in breast cancers leads to insulin/IGF-I hybrid receptor overexpression: evidence for a second mechanism of IGF-I signaling. (1999) (265)
- Increased aggressiveness of thyroid cancer in patients with Graves' disease. (1990) (265)
- Insulin-like growth factor-I receptors are overexpressed and predict a low risk in human breast cancer. (1993) (262)
- Chronic exposure to free fatty acids or high glucose induces apoptosis in rat pancreatic islets: possible role of oxidative stress. (2002) (261)
- A polymorphism (K121Q) of the human glycoprotein PC-1 gene coding region is strongly associated with insulin resistance. (1999) (255)
- Adiponectin relationship with lipid metabolism is independent of body fat mass: evidence from both cross-sectional and intervention studies. (2004) (249)
- The role of insulin receptors and IGF-I receptors in cancer and other diseases (2008) (240)
- A novel autocrine loop involving IGF-II and the insulin receptor isoform-A stimulates growth of thyroid cancer. (2002) (231)
- Levothyroxine Monotherapy Cannot Guarantee Euthyroidism in All Athyreotic Patients (2011) (229)
- The changing epidemiology of thyroid cancer: why is incidence increasing? (2015) (223)
- Insulin Receptor Isoforms in Physiology and Disease: An Updated View (2017) (222)
- BRAF(V600E) mutation and the biology of papillary thyroid cancer. (2008) (216)
- Insulin receptor expression and function in human breast cancer cell lines. (1992) (213)
- A variation in 3' UTR of hPTP1B increases specific gene expression and associates with insulin resistance. (2002) (202)
- Androgens up-regulate the insulin-like growth factor-I receptor in prostate cancer cells. (2005) (202)
- The role of insulin receptors and IGF-I receptors in cancer and other diseases. (2008) (199)
- Early diagnosis by genetic analysis of differentiated thyroid cancer metastases in small lymph nodes. (1997) (184)
- Role of ATP production and uncoupling protein-2 in the insulin secretory defect induced by chronic exposure to high glucose or free fatty acids and effects of peroxisome proliferator-activated receptor-gamma inhibition. (2002) (184)
- The IGF system in thyroid cancer: new concepts (2001) (174)
- In IGF-I receptor-deficient leiomyosarcoma cells autocrine IGF-II induces cell invasion and protection from apoptosis via the insulin receptor isoform A (2002) (169)
- Insulin, insulin receptors, and cancer (2016) (158)
- Metformin restores insulin secretion altered by chronic exposure to free fatty acids or high glucose: a direct metformin effect on pancreatic beta-cells. (2000) (156)
- The Q allele variant (GLN121) of membrane glycoprotein PC-1 interacts with the insulin receptor and inhibits insulin signaling more effectively than the common K allele variant (LYS121). (2001) (156)
- The role of thyroid-stimulating antibodies of Graves' disease in differentiated thyroid cancer. (1988) (153)
- Outcome of differentiated thyroid cancer in Graves' patients. (1998) (153)
- Tumors, IGF-2, and hypoglycemia: insights from the clinic, the laboratory, and the historical archive. (2013) (152)
- The frequency of cold thyroid nodules and thyroid malignancies in patients from an iodine‐deficient area (1987) (149)
- Thyroid hemiagenesis: prevalence in normal children and effect on thyroid function. (2003) (144)
- Papillary thyroid cancer incidence in the volcanic area of Sicily. (2009) (142)
- Insulin receptor isoforms and insulin-like growth factor receptor in human follicular cell precursors from papillary thyroid cancer and normal thyroid. (2011) (138)
- Regional variations of iodine nutrition and thyroid function during the neonatal period in Europe. (1986) (138)
- Graves' disease, thyroid nodules and thyroid cancer (2001) (133)
- Increasing incidence of thyroid cancer: controversies explored (2013) (129)
- The role of membrane glycoprotein plasma cell antigen 1/ectonucleotide pyrophosphatase phosphodiesterase 1 in the pathogenesis of insulin resistance and related abnormalities. (2008) (128)
- Subclinical hypothyroidism in early childhood: a frequent outcome of transient neonatal hyperthyrotropinemia. (2002) (128)
- Risk factors for congenital hypothyroidism: results of a population case-control study (1997-2003). (2005) (124)
- Iodine-induced thyrotoxicosis in Kivu, Zaire (1996) (119)
- Levothyroxine and Potassium Iodide Are Both Effective in Treating Benign Solitary Solid Cold Nodules of the Thyroid (1995) (117)
- High frequency of cancer in cold thyroid nodules occurring at young age. (1989) (117)
- Increased adipose tissue PC-1 protein content, but not tumour necrosis factor-a gene expression, is associated with a reduction of both whole body insulin sensitivity and insulin receptor tyrosine-kinase activity (1997) (106)
- Solitary autonomously functioning thyroid nodules and iodine deficiency. (1983) (106)
- Insulin receptor isoform A and insulin-like growth factor II as additional treatment targets in human osteosarcoma. (2009) (106)
- Peroxisomal proliferator-activated receptor-gamma agonists induce partial reversion of epithelial-mesenchymal transition in anaplastic thyroid cancer cells. (2006) (106)
- Insulin/IGF-I hybrid receptors play a major role in IGF-I signaling in thyroid cancer. (1999) (104)
- Insulin receptor expression and clinical outcome in node-negative breast cancer. (1997) (104)
- Overexpression of insulin receptors in fibroblast and ovary cells induces a ligand-mediated transformed phenotype. (1991) (102)
- Risk-adapted management of differentiated thyroid cancer assessed by a sensitive measurement of basal serum thyroglobulin. (2011) (102)
- HMGA1 inhibits the function of p53 family members in thyroid cancer cells. (2006) (101)
- Signaling differences from the A and B isoforms of the insulin receptor (IR) in 32D cells in the presence or absence of IR substrate-1. (2003) (100)
- High prevalence of differentiated thyroid carcinoma in acromegaly (2005) (99)
- Heavy metals in the volcanic environment and thyroid cancer (2017) (98)
- An ATG repeat in the 3'-untranslated region of the human resistin gene is associated with a decreased risk of insulin resistance. (2002) (98)
- Differential Gene Expression Induced by Insulin and Insulin-like Growth Factor-II through the Insulin Receptor Isoform A* (2003) (96)
- The nuclear envelope. The major site of insulin binding in rat liver nuclei. (1978) (95)
- Childhood IQ measurements in infants with transient congenital hypothyroidism * (1995) (90)
- Proinsulin binds with high affinity the insulin receptor isoform A and predominantly activates the mitogenic pathway. (2012) (89)
- Negative/low expression of the Met/hepatocyte growth factor receptor identifies papillary thyroid carcinomas with high risk of distant metastases. (1997) (86)
- Longitudinal study of thyroid function in children with mild hyperthyrotropinemia at neonatal screening for congenital hypothyroidism. (2008) (85)
- ASPB10 insulin induction of increased mitogenic responses and phenotypic changes in human breast epithelial cells: Evidence for enhanced interactions with the insulin‐like growth factor‐I receptor (1997) (85)
- Transient impairment of thyroid function in newborn from an area of endemic goiter. (1984) (82)
- Comparison of the in vitro effect of biguanides and sulfonylureas on insulin binding of its receptors in target cells. (1982) (82)
- Papillary thyroid microcarcinomas: a comparative study of the characteristics and risk factors at presentation in two cancer registries. (2013) (82)
- Role of metformin in treatment of diabetes mellitus (1987) (81)
- A cluster of three single nucleotide polymorphisms in the 3'-untranslated region of human glycoprotein PC-1 gene stabilizes PC-1 mRNA and is associated with increased PC-1 protein content and insulin resistance-related abnormalities. (2001) (80)
- Clinical and molecular mechanisms favoring cancer initiation and progression in diabetic patients. (2013) (80)
- Increased serum thyroglobulin levels in patients with nontoxic goiter. (1978) (80)
- Growth Hormone Levels in Diabetes: Correlation with the Clinical Control of the Disease (1976) (78)
- p53 family proteins in thyroid cancer. (2007) (78)
- Overexpression of the C-MET/HGF receptor in human thyroid carcinomas derived from the follicular epithelium (1995) (78)
- Elevated PC-1 content in cultured skin fibroblasts correlates with decreased in vivo and in vitro insulin action in nondiabetic subjects: evidence that PC-1 may be an intrinsic factor in impaired insulin receptor signaling. (1998) (75)
- Intracellular binding sites for insulin are immunologically distinct from those on the plasma membrane (1977) (72)
- Tyrosine kinase inhibitor STI571 enhances thyroid cancer cell motile response to Hepatocyte Growth Factor (2001) (71)
- Insulin Receptors in Breast Cancer (1996) (71)
- Insulin stimulation of nucleoside triphosphatase activity in isolated nuclear envelopes. (1982) (71)
- Insulin has multiple antiamyloidogenic effects on human neuronal cells. (2013) (70)
- Differential signaling activation by insulin and insulin-like growth factors I and II upon binding to insulin receptor isoform A. (2009) (70)
- Intragastric Balloon in Association with Lifestyle and/or Pharmacotherapy in the Long-Term Management of Obesity (2012) (69)
- Increased thyroid cancer incidence in a basaltic volcanic area is associated with non-anthropogenic pollution and biocontamination (2016) (68)
- Efficacy of real‐time continuous glucose monitoring on glycaemic control and glucose variability in type 1 diabetic patients treated with either insulin pumps or multiple insulin injection therapy: a randomized controlled crossover trial (2015) (68)
- Insulin and its analogs: actions via insulin and IGF receptors (2010) (66)
- Defects in Insulin-Receptor Internalization and Processing in Monocytes of Obese Subjects and Obese NIDDM Patients (1989) (65)
- High prevalence of overweight and obesity in 11-15-year-old children from Sicily. (2006) (64)
- Insulin and hybrid insulin/IGF receptors are major regulators of breast cancer cells. (2003) (64)
- Loss-of-function mutation of the GPR40 gene associates with abnormal stimulated insulin secretion by acting on intracellular calcium mobilization. (2008) (64)
- Dual regulation of glycogen metabolism by insulin and insulin-like growth factors in human hepatoma cells (HEP-G2). Analysis with an anti-receptor monoclonal antibody. (1984) (64)
- In situ evidence of neoplastic cell phagocytosis by macrophages in papillary thyroid cancer. (1997) (63)
- The Q121 PC-1 variant and obesity have additive and independent effects in causing insulin resistance. (2001) (60)
- A diffuse sclerosing variant of papillary thyroid carcinoma: clinical and pathologic features and outcomes of 34 consecutive cases. (2011) (60)
- Increased mortality in patients with differentiated thyroid cancer associated with Graves' disease. (2013) (60)
- p73 tumor-suppressor activity is impaired in human thyroid cancer. (2003) (60)
- Novel LMF1 nonsense mutation in a patient with severe hypertriglyceridemia. (2009) (60)
- Overexpression of membrane glycoprotein PC-1 in MDA-MB231 breast cancer cells is associated with inhibition of insulin receptor tyrosine kinase activity. (1996) (59)
- Insulin receptor overexpression in 184B5 human mammary epithelial cells induces a ligand‐dependent transformed phenotype (1995) (59)
- Progestins increase insulin receptor content and insulin stimulation of growth in human breast carcinoma cells. (1990) (59)
- Very severely obese patients have a high prevalence of type 2 diabetes mellitus and cardiovascular disease (2013) (55)
- High-affinity insulin binding to an atypical insulin-like growth factor-I receptor in human breast cancer cells. (1992) (53)
- Long‐term outcome of patients with insular carcinoma of the thyroid (2002) (52)
- Activation of the hepatocyte growth factor (HGF)-Met system in papillary thyroid cancer: biological effects of HGF in thyroid cancer cells depend on Met expression levels. (2004) (52)
- Etiological factors of endemic goiter in north-eastern Sicily (1978) (51)
- Research resource: New and diverse substrates for the insulin receptor isoform A revealed by quantitative proteomics after stimulation with IGF-II or insulin. (2011) (51)
- Usefulness of recombinant human thyrotropin in the radiometabolic treatment of selected patients with thyroid cancer. (2001) (50)
- Comparison of Combined Therapies in Treatment of Secondary Failure to Glyburide (1992) (50)
- Evidence for genetic epistasis in human insulin resistance: the combined effect of PC-1 (K121Q) and PPARγ2 (P12A) polymorphisms (2003) (50)
- Novel cross-talk between IGF-IR and DDR1 regulates IGF-IR trafficking, signaling and biological responses (2015) (49)
- IGF‐II Binding to Insulin Receptor Isoform A Induces a Partially Different Gene Expression Profile from Insulin Binding (2004) (48)
- Insulin autoimmune syndrome (Hirata Disease) in European Caucasians taking α‐lipoic acid (2014) (47)
- Descriptive Epidemiology of Human Thyroid Cancer: Experience From a Regional Registry and The “Volcanic Factor” (2013) (46)
- Endemic cretinism in Sicily (1981) (45)
- Functional insulin receptors are overexpressed in thyroid tumors (1999) (45)
- Prevention and treatment of endemic iodine-deficiency goiter by iodination of a municipal water supply. (1986) (45)
- Serum thyroglobulin levels in the newborn. (1981) (44)
- A radioimmunoassay for human thyroglobulin: methodology and clinical applications (1977) (43)
- Levels of histone acetylation in thyroid tumors. (2011) (43)
- Growth hormone release during the first year of life in relation to sleep-wake periods. (1971) (43)
- Thyroid cancer in thyroglossal duct cysts requires a specific approach due to its unpredictable extension. (2013) (43)
- The p53-homologue p63 may promote thyroid cancer progression. (2005) (42)
- Role of cyclic AMP response element-binding protein in insulin-like growth factor-i receptor up-regulation by sex steroids in prostate cancer cells. (2009) (42)
- In vivo regulation of cell surface and intracellular insulin binding sites by insulin. (1978) (41)
- Diabetes: Diabetes therapy and cancer risk (2009) (41)
- Cold thyroid nodule reduction with L-thyroxine can be predicted by initial nodule volume and cytological characteristics. (1996) (40)
- Human insulin receptor radioimmunoassay: applicability to insulin-resistant states. (1989) (40)
- Metformin normalizes insulin binding to monocytes from obese nondiabetic subjects and obese type II diabetic patients. (1983) (39)
- Exclusion of c-Abl from the Nucleus Restrains the p73 Tumor Suppression Function* (2003) (39)
- PC-1 content in skeletal muscle of non-obese, non-diabetic subjects: relationship to insulin receptor tyrosine kinase and whole body insulin sensitivity (1996) (39)
- Monomeric ß-amyloid interacts with type-1 insulin-like growth factor receptors to provide energy supply to neurons (2015) (38)
- Reactivation of p53 mutants by p53 reactivation and induction of massive apoptosis in thyroid cancer cells (2012) (38)
- Interleukin-4 stimulates papillary thyroid cancer cell survival: implications in patients with thyroid cancer and concomitant Graves' disease. (2004) (37)
- Time to Separate Persistent From Recurrent Differentiated Thyroid Cancer: Different Conditions With Different Outcomes (2018) (37)
- Latero-cervical lymph node metastases (N1b) represent an additional risk factor for papillary thyroid cancer outcome (2017) (37)
- Glyburide and tolbutamide induce desensitization of insulin release in rat pancreatic islets by different mechanisms. (1992) (36)
- 17β-Estradiol Up-regulates the Insulin-like Growth Factor Receptor through a Nongenotropic Pathway in Prostate Cancer Cells (2007) (35)
- Adverse glycaemic effects of cancer therapy: indications for a rational approach to cancer patients with diabetes. (2018) (35)
- Insulin Analogs and Cancer (2012) (35)
- Role of c-Abl in Directing Metabolic versus Mitogenic Effects in Insulin Receptor Signaling* (2007) (35)
- Insulin internalization into monocytes is decreased in patients with type II diabetes mellitus. (1986) (35)
- ΔNp73α inhibits PTEN expression in thyroid cancer cells (2009) (34)
- Glucose Modulates Glucose Transporter Affinity, Glucokinase Activity, and Secretory Response in Rat Pancreatic β-Cells (1993) (34)
- A soluble PC-1 circulates in human plasma: relationship with insulin resistance and associated abnormalities. (1999) (34)
- Obesity and cancer. (2006) (33)
- Endocytosis, recycling, and degradation of the insulin receptor. Studies with monoclonal antireceptor antibodies that do not activate receptor kinase. (1989) (33)
- HMGA1 protein is a positive regulator of the insulin-like growth factor-I receptor gene. (2010) (33)
- Low-Dose Bedtime NPH Insulin in Treatment of Secondary Failure to Glyburide (1989) (32)
- Reactivation of p53 mutants by prima-1 [corrected] in thyroid cancer cells. (2012) (31)
- Prognostic Factors for Adrenocortical Carcinoma Outcomes (2016) (31)
- Influence of early-life and parental factors on childhood overweight and obesity (2016) (31)
- Insulin binding sites on the nuclear envelope: potential relationship to mRNA metabolism (1982) (31)
- Androgens Upregulate the Insulin-like Growth Factor-I Receptor in Prostate Cancer Cells (2005) (31)
- Studies on the goiter endemia in Sicily (1988) (31)
- Regenerating rat liver: insulin and glucagon serum levels and receptor binding. (1981) (30)
- The insulin receptor content is increased in breast cancers initiated by three different oncogenes in transgenic mice (1997) (30)
- The diagnostic use of the rhTSH/thyroglobulin test in differentiated thyroid cancer patients with persistent disease and low thyroglobulin levels (2003) (30)
- Biological Effects of Insulin and Its Analogs on Cancer Cells With Different Insulin Family Receptor Expression (2014) (30)
- Outcome of the Diffuse Sclerosing Variant of Papillary Thyroid Cancer: A Meta-Analysis. (2016) (30)
- Thyrospheres From Normal or Malignant Thyroid Tissue Have Different Biological, Functional, and Genetic Features. (2015) (29)
- The BRAF(V600E) mutation influences the short- and medium-term outcomes of classic papillary thyroid cancer, but is not an independent predictor of unfavorable outcome. (2014) (29)
- Insulin‐stimulated cell growth in insulin receptor substrate‐1–deficient ZR‐75‐1 cells is mediated by a phosphatidylinositol‐3‐kinase–independent pathway (1998) (29)
- Neural network analysis for evaluating cancer risk in thyroid nodules with an indeterminate diagnosis at aspiration cytology: identification of a low-risk subgroup. (2004) (27)
- An intact and functional soluble form of the insulin receptor is secreted by cultured cells. (1993) (27)
- Efficacy of combined treatments in NIDDM patients with secondary failure to sulphonylureas. Is it predictable? (1998) (27)
- Direct effects of biguanides on glucose utilization in vitro. (1987) (26)
- Secular Trends in the Prevalence of Overweight and Obesity in Sicilian Schoolchildren Aged 11–13 Years During the Last Decade (2012) (26)
- Treatment of NIDDM patients with secondary failure to glyburide: comparison of the addition of either metformin or bed-time NPH insulin to glyburide. (1991) (25)
- False-positive findings on (131)I whole-body scans because of posttraumatic superficial scabs. (2002) (25)
- Insulin-resistant MDA-MB231 human breast cancer cells contain a tyrosine kinase inhibiting activity. (1993) (25)
- Type 2 diabetic patients with Graves' disease have more frequent and severe Graves' orbitopathy. (2015) (24)
- Rethinking the Relationship between Insulin and Cancer (2020) (24)
- Chronic exposure to high leucine impairs glucose-induced insulin release by lowering the ATP-to-ADP ratio. (2001) (23)
- Graves’ Orbitopathy: Extraocular Muscle/Total Orbit Area Ratio is Positively Related to the Clinical Activity Score (2012) (23)
- Immunostaining for Met/HGF receptor may be useful to identify malignancies in thyroid lesions classified suspicious at fine-needle aspiration biopsy. (2001) (23)
- Structural and functional studies of insulin receptors in human breast cancer (2004) (22)
- Progestin regulation of insulin and insulin-like growth factor I receptors in cultured human breast cancer cells (2005) (22)
- Growth Hormone Kinetics in Diabetic Patients (1975) (22)
- Acute changes in clinical parameters and thyroid function peripheral markers following L-T4 withdrawal in patients totally thyroidectomized for thyroid cancer (2006) (22)
- Insulin receptor tyrosine kinase activity is reduced in monocytes from non-obese normoglycaemic insulin-resistant subjects (1993) (22)
- Insulin and glucagon receptors in Morris hepatomas of varying growth rates. (1979) (22)
- Improvement With Metformin in Insulin Internalizaron and Processing in Monocytes From NIDDM Patients (1990) (22)
- Long-acting insulin analogs and cancer. (2018) (21)
- Improvement with metformin in insulin internalization and processing in monocytes from NIDDM patients. (1990) (21)
- Sporadic amplification of the insulin receptor gene in human breast cancer (1997) (21)
- Early molecular defects in human insulin resistance: studies in healthy subjects with low insulin sensitivity. (1997) (21)
- Phenformin Increases Insulin Binding to Human Cultured Breast Cancer Cells (1980) (21)
- Thyroid cancer cell resistance to gefitinib depends on the constitutive oncogenic activation of the ERK pathway. (2013) (20)
- Comparison of solubilized and purified plasma membrane and nuclear insulin receptors. (1988) (20)
- Sleep-associated growth hormone (GH) release in schizophrenia. (1974) (20)
- The intravenous insulin tolerance test is an accurate method for screening a general population for insulin resistance and related abnormalities (1999) (20)
- Appearance of anti TSH-receptor antibodies and clinical Graves’ disease after radioiodine therapy for hyperfunctioning thyroid adenoma (1999) (19)
- Interleukin-1 blocks insulin and insulin-like growth factor-stimulated growth in MCF-7 human breast cancer cells by inhibiting receptor tyrosine kinase activity. (1996) (19)
- Chronic exposure to glibenclamide impairs insulin secretion in isolated rat pancreatic islets (1991) (19)
- TAp73α Increases p53 Tumor Suppressor Activity in Thyroid Cancer Cells via the Inhibition of Mdm2-Mediated Degradation (2008) (19)
- Epidemiology and clinical characteristics of endemic cretinism in Sicily (1990) (19)
- A radioimmunoassay for human thyrotropin. (1969) (19)
- Longitudinal study on goiter prevalence and goitrogen factors in northeastern Sicily (1996) (19)
- Sex Steroids Upregulate the IGF‐1R in Prostate Cancer Cells through a Nongenotropic Pathway (2009) (19)
- Adiponectin increases glucose-induced insulin secretion through the activation of lipid oxidation (2013) (18)
- Intracellular insulin processing is altered in monocytes from patients with type II diabetes mellitus. (1987) (18)
- 17beta-estradiol up-regulates the insulin-like growth factor receptor through a nongenotropic pathway in prostate cancer cells. (2007) (18)
- Insulin degludec in the first trimester of pregnancy: Report of two cases (2017) (18)
- Selective Insulin Receptor Modulators (SIRM): A New Class of Antidiabetes Drugs? (2012) (18)
- A radioimmunoassay for thyroxine in unextracted serum. (1975) (17)
- Several Site-specific Cancers are Increased in the Volcanic Area in Sicily. (2015) (17)
- A14-[125I]monoiodoinsulin purified by different high-performance liquid chromatographic procedures and by polyacrylamide gel electrophoresis: preparation, immunochemical properties and receptor binding affinity. (1986) (17)
- Effect of dexamethasone on thyroid hormone response to TSH. (1975) (17)
- Lymph node location is a risk factor for papillary thyroid cancer-related death (2018) (17)
- Use of insulin detemir during pregnancy. (2010) (16)
- Cardiac arrest after intravenous calcium administration for calcitonin stimulation test. (2014) (15)
- Intake of Boron, Cadmium, and Molybdenum enhances rat thyroid cell transformation (2017) (15)
- Thyroid Cancer in the Pediatric Age in Sicily: Influence of the Volcanic Environment. (2017) (15)
- Thyroid-pituitary function in eight anencephalic infants. (1980) (15)
- Serum thyroglobulin levels are elevated in newborns from iodine-deficient areas. (1986) (15)
- Thyroglobulin release after graded endogenous thyrotropin stimulation in man: lack of correlation with thyroid hormone response. (1984) (15)
- In thyroid cancer cell lines expression of periostin gene is controlled by p73 and is not related to epigenetic marks of active transcription (2011) (15)
- Integrated insulin pump therapy with continuous glucose monitoring for improved adherence: technology update (2015) (15)
- Effects of biguanides and sulfonylureas on insulin receptors in cultured cells. (1984) (15)
- Increased Thyroid Cancer Incidence in Volcanic Areas: A Role of Increased Heavy Metals in the Environment? (2020) (14)
- Identification and initial characterization of insulin receptor-like immunoreactivity in human plasma. (1992) (14)
- Severe Graves' ophthalmopathy after percutaneous ethanol injection in a nontoxic thyroid nodule. (2012) (14)
- Chronic Exposure to High Glucose and Impairment of K+-Channel Function in Perifused Rat Pancreatic Islets (1990) (14)
- Tall cell and diffuse sclerosing variants of papillary thyroid cancer: outcome and predicting value of risk stratification methods (2017) (14)
- Copper addition prevents the inhibitory effects of interleukin 1-β on rat pancreatic islets (2006) (13)
- ATP and other nucleoside triphosphates inhibit the binding of insulin to its receptor. (1984) (13)
- Insulin and the regulation of isolated nuclei and nuclear subfractions: potential relationship to mRNA metabolism. (1985) (13)
- Treatment of hemangiopericytoma-induced hypoglycemia with growth hormone and corticosteroids. (1999) (12)
- Rats that are made insulin resistant by glucosamine treatment have impaired skeletal muscle insulin receptor phosphorylation. (2003) (12)
- Rare diseases in clinical endocrinology: a taxonomic classification system (2015) (12)
- Seasonal variations in TSH serum levels in athyreotic patients under L‐thyroxine replacement monotherapy (2017) (12)
- The effect of short-term triiodothyronine administration on thyroxine response to exogenous TSH in man. (1975) (12)
- Insulin/insulin-like growth factor I hybrid receptors overexpression is not an early defect in insulin-resistant subjects. (2000) (12)
- Efficacy of Botulinum Toxin A for Treating Cramps in Diabetic Neuropathy (2018) (12)
- Radioimmunoassay for human insulin-like growth factor-I receptor: applicability to breast carcinoma specimens and cell lines. (1991) (11)
- HMGA 1 Inhibits the Function of p 53 Family Members in Thyroid Cancer Cells (2006) (11)
- [Iodine deficiency and iodine prophylaxis experience in Sicily]. (1998) (11)
- 35th Annual meeting of the European Association for the Study of Diabetes. Brussels, Belgium, 28 September-2 October, 1999. Abstracts. (1999) (11)
- A ten-year (1989–1998) perspective study of the incidence of Type 1 diabetes in the district of Catania (Sicily) in a 0–14 year age group (2002) (10)
- Glucose transport, phosphorylation, and utilization in isolated porcine pancreatic islets. (1995) (10)
- Heavy Metals in the Environment and Thyroid Cancer (2021) (10)
- Complementary use of gel permeation and reversed-phase liquid chromatography for the analysis of A14-[125I]insulin and its degradation products in isolated human monocytes. (1986) (10)
- Healing of chronic necrobiosis lipoidica lesions in a Type 1 diabetic patient after pancreas-kidney transplantation: A case report (2007) (10)
- Spontaneous fluctuations of human placental lactogen during normal pregnancy. (1975) (10)
- Chronic exposure to high glucose and impairment of K(+)-channel function in perifused rat pancreatic islets. (1990) (10)
- Concentration of metals and trace elements in the normal human and rat thyroid: comparison with muscle and adipose tissue and volcanic versus control areas. (2019) (9)
- Phenformin has opposite effects on insulin and growth hormone binding to IM-9 lymphocytes. (1982) (8)
- Thyrotropin and prolactin response to intraspinal TRH administration in man. (1977) (8)
- Botulinum toxin for burning mouth syndrome (2017) (8)
- Is thyroid cancer increasing in incidence and aggressiveness? (2020) (8)
- Effect of metformin on insulin binding to receptors in cultured human lymphocytes and cancer cells (1982) (8)
- Differentiated thyroid cancer in children: Heterogeneity of predictive risk factors (2018) (8)
- Metformin and insulin receptors. (1984) (8)
- QUALITY OF LIFE AND TREATMENT SATISFACTION IN PATIENTS WITH TYPE 1DIABETES: A COMPARISON BETWEEN CONTINUOUS SUBCUTANEOUS INSULININJECTION AND MULTIPLE DAILY INJECTIONS (2007) (7)
- Prevalence and Clinical Characteristics of Children and Adolescents with Metabolically Healthy Obesity: Role of Insulin Sensitivity (2020) (7)
- Measurement of iodine before 131I in thyroid cancer (1994) (7)
- Effect of low-dose tungsten on human thyroid stem/precursor cells and their progeny. (2019) (7)
- Inhibition by L-triiodothyronine and dexamethasone of TSH response to thyrotropin releasing hormone in man. (1972) (7)
- Decreased reverse triiodothyronine (RT3) concentration in amniotic fluid in fetal hypothyroidism. (1977) (7)
- The iodine/thiocyanate ratio (1980) (6)
- Anaplastic Thyroid Cancer in Sicily: The Role of Environmental Characteristics (2017) (6)
- Glycemic control and cardiovascular diseases in Type 2 diabetes mellitus. Beyond fasting glycemia and glycosylated hemoglobin. (2000) (6)
- Short-term adverse effects of anticancer drugs in patients with type 2 diabetes (2019) (6)
- Abnormal 1-hour post-load glycemia during pregnancy impairs post-partum metabolic status: a single-center experience (2018) (6)
- Corticosteroid Pulse Therapy for Graves' Ophthalmopathy Reduces the Relapse Rate of Graves' Hyperthyroidism (2020) (6)
- Type 2 diabetes and cancer: problems and suggestions for best patient management (2020) (6)
- Thyroid Stem Cells But Not Differentiated Thyrocytes Are Sensitive to Slightly Increased Concentrations of Heavy Metals (2021) (5)
- Inhibition of the high-affinity glucose transporter GLUT 1 affects the sensitivity to glucose in a hamster-derived pancreatic beta cell line (HIT) (1993) (5)
- Circadian variations of human growth hormone serum levels. Longitudinal study. (1971) (5)
- Triiodothyronine and thyrotropin-releasing hormone interaction on TSH release in man. (1972) (5)
- The biological and clinical roles of increased insulin receptors in human breast cancer. (1992) (5)
- Comment on: Yang et al. (2010) Associations of Hyperglycemia and Insulin Usage With the Risk of Cancer in Type 2 Diabetes: The Hong Kong Diabetes Registry. Diabetes;59:1254–1260 (2010) (5)
- Direct Regulation of Nuclear Functions by Insulin: Relationship to mRNA Metabolism (1985) (5)
- Risk for Coexistent Autoimmune Diseases in Familial and Sporadic Type 1 Diabetes is Related to Age at Diabetes Onset. (2021) (5)
- Iodine Supplementation to a Public Water Supply: An Efficient Method for Correcting Iodine Deficiency (1993) (5)
- Relationship between insulin receptor tyrosine kinase activity and internalization in monocytes of non-insulin-dependent diabetes mellitus patients. (1993) (4)
- Iodine-induced thyrotoxicosis in Kivu Zaire [letter] (1996) (4)
- Interleukin-1β inhibition of insulin release in rat pancreatic islets: Possible involvement of G-proteins in the signal transduction pathway (1995) (4)
- Personality traits and mental prognosis in patients with congenital hypothyroidism not treated from early life (1988) (4)
- Impact of unhealthy childhood and unfavorable parents' characteristics on adiposity in schoolchildren (2019) (4)
- Incidence of type I diabetes in the district of Catania, Sicily (1994) (4)
- Pharmacologic therapy of patients with pituitary tumors secreting prolactin, growth hormone and adrenocorticotropin. (1980) (4)
- Action of insulin at the nuclear envelope (1991) (3)
- Insulin Receptor Isoforms Differently Regulate Cell Proliferation and Apoptosis in the Ligand-Occupied and Unoccupied State (2021) (3)
- Rapid regulation of plasma membrane insulin receptors (1980) (3)
- Characterization of insulin degrading activity in subcellular fractions of human monocytes (1988) (3)
- Early occurrence of a thyroid carcinoma in a patient who developed Graves’ disease after treatment for Hodgkin’s disease (1995) (3)
- Recommendations concerning iodine prophylaxis. (1995) (3)
- Response: Re: Papillary Thyroid Cancer Incidence in the Volcanic Area of Sicily (2010) (3)
- Glucose regulates both glucose transport and the glucose transporter gene expression in a hamster-derived pancreatic Beta-cell line (HIT) (1991) (3)
- High incidence of anti-GH antibodies in subjects treated with the GH clinical preparation available in Italy (1980) (3)
- Aggressive fibromatosis of the neck initiated after thyroidectomy (2006) (3)
- Basal insulin and cardiovascular and other outcomes. (2012) (3)
- Maternal Diabetes Impairs Insulin and IGF-1 Receptor Expression and Signaling in Human Placenta (2021) (2)
- Response to Letter to the Editor: [Time to Separate Persistent from Recurrent Differentiated Thyroid Cancer: Different Conditions with Different outcomes]. (2019) (2)
- Overexpression of insulin receptors in NIH-3T3 cells induces a ligand-mediated transformed phenotype. (1991) (2)
- Interleukin-1 beta inhibition of insulin release in rat pancreatic islets: possible involvement of G-proteins in the signal transduction pathway. (1995) (2)
- BRAF mutation and the biology of papillary thyroid cancer (2008) (2)
- Improving the prediction of malignancy in cytologically suspicious thyroid nodules (2013) (2)
- Re: Insulin, insulin-like growth factor-I, and risk of breast cancer in postmenopausal women. (2009) (2)
- Different effects of glucose and glyburide on insulin secretion in rat pancreatic islets pre-exposed to interleukin-1β. Possible involvement of K+ and Ca2+ channels (1993) (2)
- Measurement of reverse triiodothyronine in dried blood spot: methodology and clinical application as a screening procedure for detection of congenital hypothyroidism. (1980) (2)
- TAp 73 A Increases p 53 Tumor Suppressor Activity in Thyroid Cancer Cells via the Inhibition of Mdm 2-Mediated Degradation (2008) (2)
- Cytogenetic analysis in congenital hypothyroidism (1990) (2)
- Thyroxine or Iodine Therapy for Thyroid Nodules (1995) (1)
- Different Effects of the Insulin Receptor Isoforms on 32D Cell Growth and Differentiation (2017) (1)
- [Thyroid function in diabetes mellitus]. (1967) (1)
- Insulin and Insulin-like Growth Factor-I ( IGF-I ) Receptor Overexpression in Breast Cancers Leads to Insulin / IGF-I Hybrid Receptor Overexpression : Evidence for a Second Mechanism of IGF-I Signaling 1 (1999) (1)
- A reduced glut 4 content in adipose tissue is not an early defect in the development of human insulin resistance (1995) (1)
- Reverse T3 and screening for congenital hypothyroidism (1978) (1)
- Thyroglobuline levels in an endemic goiter population: effect of iodine supplementation (1984) (1)
- Receptor in Prostate Cancer Cells Androgens Upregulate the Insulin-like Growth Factor-I Updated (2005) (1)
- p73 tumor suppressor activity is impaired in thyroid cancer (2003) (1)
- Effect of dexamethasone on triiodothyronine (T3) response to TSH. (1975) (1)
- Diabetic mastopathy: A case report (2003) (1)
- [21] FUNCTIONAL ANALYSIS OF A NOVEL LMF1 NONSENSE MUTATION ASSOCIATED TO SEVERE HYPERTRIGLYCERIDEMIA (2009) (1)
- [Thyroid function in the normal aged subject]. (1967) (0)
- Considerations on preliminary results from triiodothyronine (T3) catabolism and distribution studies in man. (1973) (0)
- Managing impaired glucose metabolism in acromegalic subjects (2010) (0)
- 113m indium for liver scanning. (1969) (0)
- [Clinical and instrumental study of thyroid diseases in relation to surgical treatment. I. Basedow's disease and hyperthyroidism]. (1968) (0)
- [Physiopathology of the autonomous thyroid nodule]. (1993) (0)
- [Oral hypoglycemics and insulin action. Post-receptor effects]. (1986) (0)
- [Receptor status and ovarian function in carcinoma of the breast]. (1989) (0)
- THYROXINE OR IODINE THERAPY FOR THYROID NODULES. AUTHOR'S REPLY (1995) (0)
- Response to synthetic thyrotropin releasing hormone in man. Preliminary report. (1971) (0)
- Insulin Regulation of Nuclear Envelope Functions: Relationship to mRNA Metabolism (1984) (0)
- P39 Both the insulin receptor isoform a and the IGF-I receptor mediate the effects of IGF-II in human thyroid stem cells (2010) (0)
- [Association of diabetes mellitus and thyroid diseases]. (1967) (0)
- The Effect of Thyroid Stimulating Immunoglobulins (TSI) on Thyroid Camp: Comparison with TSH Activity (1987) (0)
- P-16 Insulin/IGF system in human pituitary tumour: clinical and patho-biological insight (2008) (0)
- 167. Botulinum toxin type A (incobotulinumtoxinA) for muscle cramps associated with diabetic neuropathy: a double-blind, placebo-controlled study (2015) (0)
- Overexpression of the insulin receptors induces ligand-mediated cell transformation in NIH-3T3 fibroblasts. (1990) (0)
- Botulinum Toxin For Muscle Cramps Associated With Diabetic Neuropathy: A Double-Blind, Placebo-Controlled Study (S20.006) (2014) (0)
- Managing impaired glucose metabolism in acromegalic subjects. (2010) (0)
- Improving the diagnosis of central hypothyroidism (2008) (0)
- /sup 113m/In FOR LIVER SCANNING. (1969) (0)
- Cooperation of p73 and p53 in anaplastic thyroid cancer cell apoptosis (2005) (0)
- P-11 Activation of cAMP responsive element binding protein 1 (CREB1) by stimulation of the Src/ERK pathway is a common mechanism underlying IGF-I receptor upregulation by androgens and estrogens in prostate cancer cells (2008) (0)
- [Contribution to the study of thyroid function in essential obesity]. (1967) (0)
- Contents, Vol. 49, 1986 (1986) (0)
- Erratum (2012) (0)
- Proinsulin stimulates biological effects through the isoform A of insulin receptor (2011) (0)
- [On the diagnostic and therapeutic use of I-131 in cancer of the thyroid gland]. (1966) (0)
- Proceedings of the International Workshop on Thyroid Cancer: Basic Science and Clinical Problems (1995) (0)
- Intake of Boron, Cadmium, and Molybdenum enhances rat thyroid cell transformation (2017) (0)
- Prof. Pietro Polosa (1921–2015) (2015) (0)
- P03-2 In prostate cancer cells metformin inhibits the cross-talk between membrane-initiated androgens and IGF-GR (2012) (0)
- [Somatotropin secretion in the 1st year of life in relation to periods of sleep and wakefulness]. (1972) (0)
- [Study of the relationships between serum cortisol and somatotropin levels in 24 hours in the pediatric age]. (1971) (0)
- [Regulation of somatotropin secretion: attempted unitary interpretation]. (1973) (0)
- [Toxic adenoma of the thyroid (study of 120 cases)]. (1968) (0)
- [Considerations on a case of myxedema with lingual thyroid ectopia demonstrable with scintigraphy after exogenous thyrotropin stimulus]. (1967) (0)
- Neonatal Hypothyroidism,even when transient, results in intellectual impairment (1994) (0)
- Proinsulin is a ligand of isoform A of the insulin receptor (2010) (0)
- [Clinical and instrumental study of thyroid diseases in relation to the indications for surgical treatment. General considerations]. (1968) (0)
- Effect of dexamethasone on tri-iodothyronine (T$sub 3$) response to TSH (1975) (0)
- Regulation of rat liver plasma membrane and intracellular insulin binding sites during diabetes, liver regeneration, and hyperinsulinism: radiolabeled hormone binding and electron microscopic autoradiograph studies. (1980) (0)
- [Clinical and instrumental study of thyroid diseases in relation to the indications for surgical treatment. IV. Simple goiter]. (1968) (0)
- Heterogeneity of Glut 4 content in adipose and muscle tissues of moderately obese patients with or without non-insulin dependent diabetes mellitus (1994) (0)
- NORMAL AND CANCER THYROID PROGENITOR CELLS: ROLE OF INSULIN RECEPTOR ISOFORMS AND INSULIN-LIKE GROWTH FACTOR RECEPTOR IN GROWTH AND DIFFERENTIATION (2010) (0)
- Thyroid Cancer: Basic Science and Clinical Problems, Taormina, December 2-4, 1993: Foreward (1995) (0)
- Involvement of c-ABL tyrosine kinase in insulin and IGF-I signaling (2005) (0)
- 120 A NOVEL MUTATION IN THE LIPASE MATURATION FACTOR 1 (LMF-1) GENE RESPONSIBLE OF SEVERE HYPERTRIGLYCERIDEMIA (2008) (0)
- Impaired response to Growth Hormone treatment in two subjects with anti-GH antibodies: role of GH aggregates (1981) (0)
- P40 Proinsulin mediates proliferative effects by activating the isoform a of the insulin receptor (2010) (0)
- Contents, Vol. 14, 1974 (1974) (0)
- P-60 Signaling differences in the A and B isoforms of the insulin receptor in 32D cells stimulated by either insulin or IGF-II in the presence of IRS-3 (2008) (0)
- Latedeaths andsurvival after childhood cancer: implications forcure (1994) (0)
- [Clinical and instrumental study of thyroid diseases in relation to surgical therapy. II. The hot nodule (toxic adenoma)]. (1968) (0)
- [Insulin resistance in type 2 diabetes. Receptor and post-receptor aspects]. (1984) (0)
- [The thyrotropic hormone]. (1970) (0)
- [Thyreopathies in the old age]. (1967) (0)
- [Clinical and instrumental study of thyroid diseases in relation to surgical therapy. 3. Cold nodules (cysts and carcinomas)]. (1968) (0)
- [Radioimunologic doseof thyrotropin hormoe. Preliinary resul]. (1970) (0)
- [Clinical and instrumental study of thyroid diseases in relation to indications for surgical treatment. General premises]. (1968) (0)
- P-117: Relationship between insulin sensitivity, insulin receptor tyrosine-kinase activity and PC-1 content (2009) (0)
- Recommendations for mass screening for congenital hypothyroidism (1978) (0)
- The insulin receptor isoform A plays a role in thyrospheres growth and differentiation (2010) (0)
- [Daily variations of blood somatotropin in children]. (1970) (0)
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