Rachel E. Klevit
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American biochemist and academic
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Rachel E. Klevitbiology Degrees
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Biochemistry
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Biology
Rachel E. Klevit's Degrees
- PhD Biochemistry University of California, Berkeley
- Bachelors Chemistry University of California, Berkeley
Why Is Rachel E. Klevit Influential?
(Suggest an Edit or Addition)According to Wikipedia, Rachel E. Klevit is professor of biochemistry, adjunct professor of chemistry, and adjunct professor of pharmacology at the University of Washington. She holds the Edmond H. Fischer-Washington Research Foundation Endowed Chair in Biochemistry. Klevit's research focuses on molecular interactions in human diseases and includes research on BRCA1, the protein ubiquitination system, and human heat shock proteins.
Rachel E. Klevit's Published Works
Published Works
- Recognition of Antimicrobial Peptides by a Bacterial Sensor Kinase (2005) (522)
- Mutant adenosine deaminase 2 in a polyarteritis nodosa vasculopathy. (2014) (514)
- UbcH7 reactivity profile reveals Parkin and HHARI to be RING/HECT hybrids (2011) (497)
- RING-type E3 ligases: master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitination. (2014) (483)
- Structure of a BRCA1–BARD1 heterodimeric RING–RING complex (2001) (473)
- Proof of principle for epitope-focused vaccine design (2014) (446)
- Binding and recognition in the assembly of an active BRCA1/BARD1 ubiquitin-ligase complex (2003) (357)
- E2–BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages (2007) (356)
- E2 enzymes: more than just middle men (2016) (344)
- A UbcH5/ubiquitin noncovalent complex is required for processive BRCA1-directed ubiquitination. (2006) (293)
- Structure of an E3:E2~Ub complex reveals an allosteric mechanism shared among RING/U-box ligases. (2012) (280)
- Zinc-dependent structure of a single-finger domain of yeast ADR1. (1988) (262)
- Mass Spectrometric and Mutational Analyses Reveal Lys-6-linked Polyubiquitin Chains Catalyzed by BRCA1-BARD1 Ubiquitin Ligase* (2004) (260)
- Solid-state NMR and SAXS studies provide a structural basis for the activation of αB-crystallin oligomers (2010) (245)
- Activation of the bacterial sensor kinase PhoQ by acidic pH. (2007) (241)
- Mutations in the DBP-deficiency protein HSD17B4 cause ovarian dysgenesis, hearing loss, and ataxia of Perrault Syndrome. (2010) (241)
- Mutations in mitochondrial histidyl tRNA synthetase HARS2 cause ovarian dysgenesis and sensorineural hearing loss of Perrault syndrome (2011) (230)
- Structural Basis for Mechanical Force Regulation of the Adhesin FimH via Finger Trap-like β Sheet Twisting (2010) (230)
- One size does not fit all: The oligomeric states of αB crystallin (2013) (230)
- N-terminal domain of αB-crystallin provides a conformational switch for multimerization and structural heterogeneity (2011) (186)
- E2s: structurally economical and functionally replete. (2011) (186)
- Pharmacological chaperone for α-crystallin partially restores transparency in cataract models (2015) (185)
- Mutations in LARS2, encoding mitochondrial leucyl-tRNA synthetase, lead to premature ovarian failure and hearing loss in Perrault syndrome. (2013) (174)
- OTUB1 co-opts Lys48-linked ubiquitin recognition to suppress E2 enzyme function. (2012) (171)
- Mapping the Functional Domains of BRCA1 (1999) (160)
- The acidic transcription activator Gcn4 binds the mediator subunit Gal11/Med15 using a simple protein interface forming a fuzzy complex. (2011) (158)
- Binding of the Catabolite Repressor Protein CcpA to Its DNA Target Is Regulated by Phosphorylation of its Corepressor HPr* (1997) (157)
- Allosteric Activation of the RNF146 Ubiquitin Ligase by a Poly(ADP-ribosyl)ation Signal (2014) (157)
- Estrogen receptor α is a putative substrate for the BRCA1 ubiquitin ligase (2007) (156)
- Activity-enhancing mutations in an E3 ubiquitin ligase identified by high-throughput mutagenesis (2013) (144)
- Solution structure of the sodium channel inactivation gate. (1999) (141)
- BRCA1 RING Domain Cancer-predisposing Mutations (2001) (136)
- Metal bridges between the PhoQ sensor domain and the membrane regulate transmembrane signaling. (2006) (131)
- The growing world of small heat shock proteins: from structure to functions (2017) (129)
- 1H NMR studies on the interaction between distamycin A and a symmetrical DNA dodecamer. (1986) (127)
- Ubiquitin in motion: structural studies of the ubiquitin-conjugating enzyme∼ubiquitin conjugate. (2011) (123)
- alphaB-crystallin: a hybrid solid-state/solution-state NMR investigation reveals structural aspects of the heterogeneous oligomer. (2009) (116)
- Common structural changes accompany the functional inactivation of HPr by seryl phosphorylation or by serine to aspartate substitution. (1989) (109)
- Binding determinants of the small heat shock protein, αB‐crystallin: recognition of the ‘IxI’ motif (2012) (103)
- Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1 (2016) (99)
- RING-Between-RING E3 Ligases: Emerging Themes amid the Variations. (2017) (96)
- Cyclic nucleotide binding GAF domains from phosphodiesterases: structural and mechanistic insights. (2009) (96)
- Interaction of calmodulin and a calmodulin-binding peptide from myosin light chain kinase: major spectral changes in both occur as the result of complex formation. (1985) (96)
- Following Ariadne's thread: a new perspective on RBR ubiquitin ligases (2012) (94)
- Solution structure of a zinc finger domain of yeast ADR1 (1990) (92)
- Estrogen receptor alpha is a putative substrate for the BRCA1 ubiquitin ligase. (2007) (92)
- The Cancer-predisposing Mutation C61G Disrupts Homodimer Formation in the NH2-terminal BRCA1 RING Finger Domain* (1998) (90)
- 1H-NMR studies of calmodulin. The nature of the Ca2+-dependent conformational change. (1984) (84)
- Gcn4-Mediator Specificity Is Mediated by a Large and Dynamic Fuzzy Protein-Protein Complex (2018) (83)
- A study of calmodulin and its interaction with trifluoperazine by high resolution 1H NMR spectroscopy (1981) (82)
- Ubiquitin Transfer from the E2 Perspective: Why is UbcH5 So Promiscuous? (2006) (81)
- Mutations in Twinkle primase-helicase cause Perrault syndrome with neurologic features (2014) (78)
- Structural insights into the conformation and oligomerization of E2~ubiquitin conjugates. (2012) (77)
- Interaction of BARD1 and HP1 Is Required for BRCA1 Retention at Sites of DNA Damage. (2015) (76)
- 1H NMR studies of calmodulin. Resonance assignments by use of tryptic fragments. (1984) (75)
- A sequence-specific transcription activator motif and powerful synthetic variants that bind Mediator using a fuzzy protein interface (2014) (74)
- Intrinsic disorder drives N-terminal ubiquitination by Ube2w (2014) (74)
- Molecular insights into RBR E3 ligase ubiquitin transfer mechanisms (2016) (71)
- Ovothiols, a family of redox-active mercaptohistidine compounds from marine invertebrate eggs. (1987) (69)
- HspB1 and Hsc70 chaperones engage distinct tau species and have different inhibitory effects on amyloid formation (2018) (68)
- E2~Ub conjugates regulate the kinase activity of Shigella effector OspG during pathogenesis (2014) (64)
- Two-dimensional NMR investigation of a bent DNA fragment: assignment of the proton resonances and preliminary structure analysis. (1987) (64)
- Regulating the Regulators: Recent Revelations in the Control of E3 Ubiquitin Ligases* (2015) (58)
- Improving two-dimensional NMR spectra by t1 ridge subtraction (1985) (57)
- Solution structure of the phosphocarrier protein HPr from Bacillus subtilis by two‐dimensional NMR spectroscopy (1992) (56)
- Identification of an unconventional E3 binding surface on the UbcH5 ∼ Ub conjugate recognized by a pathogenic bacterial E3 ligase. (2010) (55)
- Ovothiol: a novel thiohistidine compound from sea urchin eggs that confers NAD(P)H-O2 oxidoreductase activity on ovoperoxidase. (1986) (54)
- A conserved histidine modulates HSPB5 structure to trigger chaperone activity in response to stress-related acidosis (2015) (53)
- The nature of the trifluoperazine binding sites on calmodulin and troponin-C. (1984) (52)
- Modulation of CaV1.2 Channels by Mg2+ Acting at an EF-hand Motif in the COOH-terminal Domain (2005) (52)
- Mechanisms of Small Heat Shock Proteins. (2019) (52)
- The mechanism of phosphoribosyl-ubiquitination mediated by a single Legionella effector (2018) (51)
- Activation of UbcH5c~Ub is the result of a shift in interdomain motions of the conjugate bound to U-box E3 ligase E4B. (2013) (51)
- A series of point mutations reveal interactions between the calcium‐binding sites of calmodulin (1992) (50)
- Small heat shock proteins: multifaceted proteins with important implications for life (2019) (50)
- Structural consequences of histidine phosphorylation: NMR characterization of the phosphohistidine form of histidine-containing protein from Bacillus subtilis and Escherichia coli. (1994) (50)
- A Mechanism of Subunit Recruitment in Human Small Heat Shock Protein Oligomers (2015) (50)
- Dynamic interactions of proteins in complex networks: identifying the complete set of interacting E2s for functional investigation of E3‐dependent protein ubiquitination (2009) (49)
- The PhoQ histidine kinases of Salmonella and Pseudomonas spp. are structurally and functionally different: evidence that pH and antimicrobial peptide sensing contribute to mammalian pathogenesis (2008) (47)
- Spectroscopic studies of wild-type and mutant "zinc finger" peptides: determinants of domain folding and structure. (1990) (47)
- The Structure of the GAF A Domain from Phosphodiesterase 6C Reveals Determinants of cGMP Binding, a Conserved Binding Surface, and a Large cGMP-dependent Conformational Change*♦ (2008) (45)
- A Bifunctional Role for the UHRF1 UBL Domain in the Control of Hemi-methylated DNA-Dependent Histone Ubiquitylation. (2018) (44)
- Ca2+‐dependent conformational changes in bovine GCAP‐2 (1998) (44)
- A folding transition and novel zinc finger accessory domain in the transcription factor ADR1 (1999) (44)
- Engineering a Ubiquitin Ligase Reveals Conformational Flexibility Required for Ubiquitin Transfer* (2009) (44)
- Ca2+ Binding to Calmodulin and Its Role in Schizosaccharomyces pombe as Revealed by Mutagenesis and NMR Spectroscopy (*) (1995) (43)
- Zinc finger diversity (1994) (43)
- Structural Studies of HHARI/UbcH7∼Ub Reveal Unique E2∼Ub Conformational Restriction by RBR RING1 (2017) (42)
- The uses and limitations of calmodulin antagonists. (1989) (42)
- Phosphorylation of serine‐46 in HPr, a key regulatory protein in bacteria, results in stabilization of its solution structure (1995) (41)
- Two-dimensional 1H NMR studies of histidine-containing protein from Escherichia coli. 1. Sequential resonance assignments. (1986) (41)
- Sequence-specific 1H NMR resonance assignments of Bacillus subtilis HPr: use of spectra obtained from mutants to resolve spectral overlap. (1990) (40)
- Calcium-dependent solvation of the myristoyl group of recoverin. (1995) (40)
- Unraveling a bacterial hexose transport pathway. (1994) (40)
- Prediction and structural characterization of an independently folding substructure in the src SH3 domain. (1998) (39)
- Reexamination of the secondary and tertiary structure of histidine-containing protein from Escherichia coli by homonuclear and heteronuclear NMR spectroscopy. (1991) (38)
- Structure of the α-crystallin domain from the redox-sensitive chaperone, HSPB1 (2015) (38)
- Crystal Structure of the BARD1 Ankyrin Repeat Domain and Its Functional Consequences*♦ (2008) (37)
- Phosphorylation on histidine is accompanied by localized structural changes in the phosphocarrier protein, HPr from Bacillus subtilis (1997) (36)
- BARD1 is necessary for ubiquitylation of nucleosomal histone H2A and for transcriptional regulation of estrogen metabolism genes (2018) (36)
- Demonstration of protein—protein interaction specificity by NMR chemical shift mapping (1997) (36)
- BRCA1/BARD1 site-specific ubiquitylation of nucleosomal H2A is directed by BARD1 (2020) (36)
- The involvement of the arginine 17 residue in the active site of the histidine-containing protein, HPr, of the phosphoenolpyruvate:sugar phosphotransferase system of Escherichia coli. (1993) (35)
- Solution Structure of the cGMP Binding GAF Domain from Phosphodiesterase 5 (2008) (35)
- Heterogeneity of contractile proteins. Purification and characterization of two species of troponin T from rabbit fast skeletal muscle. (1984) (34)
- Acidic pH and divalent cation sensing by PhoQ are dispensable for systemic salmonellae virulence (2015) (33)
- Similarities and differences between yeast and vertebrate calmodulin: an examination of the calcium-binding and structural properties of calmodulin from the yeast Saccharomyces cerevisiae. (1993) (33)
- Structural and functional characterization of the monomeric U-box domain from E4B. (2010) (33)
- The calcium receptor and trigger (1984) (33)
- A disorder-to-order transition coupled to DNA binding in the essential zinc-finger DNA-binding domain of yeast ADR1. (1998) (33)
- Folding topology of the disulfide-bonded dimeric DNA-binding domain of the myogenic determination factor MyoD. (1992) (32)
- Epitope mapping by mutagenesis distinguishes between the two tertiary structures of the histidine-containing protein HPr. (1991) (31)
- The Essential Ubc4/Ubc5 Function in Yeast Is HECT E3-dependent, and RING E3-dependent Pathways Require Only Monoubiquitin Transfer by Ubc4* (2011) (31)
- Two-dimensional 1H NMR studies of histidine-containing protein from Escherichia coli. 2. Leucine resonance assignments by long-range coherence transfer. (1986) (31)
- Deamidation of HPr, a phosphocarrier protein of the phosphoenolpyruvate:sugar phosphotransferase system, involves asparagine 38 (HPr-1) and asparagine 12 (HPr-2) in isoaspartyl acid formation. (1993) (31)
- Involvement of the carboxy-terminal residue in the active site of the histidine-containing protein, HPr, of the phosphoenolpyruvate:sugar phosphotransferase system of Escherichia coli. (1991) (30)
- Two functionally distinct E2/E3 pairs coordinate sequential ubiquitination of a common substrate in Caenorhabditis elegans development (2017) (30)
- The Escherichia coli adenylyl cyclase complex: requirement of PTS proteins for stimulation by nucleotides. (1995) (26)
- Structures of DNA‐binding mutant zinc finger domains: Implications for DNA binding (1993) (25)
- Azidotyrosylcalmodulin derivatives. Specific probes for protein-binding domains. (1984) (25)
- Influence of N-cap mutations on the structure and stability of Escherichia coli HPr. (1996) (25)
- Mechanism of DNA binding by the ADR1 zinc finger transcription factor as determined by SPR. (2003) (24)
- pH-dependent structural modulation is conserved in the human small heat shock protein HSBP1 (2017) (24)
- Increased helix and protein stability through the introduction of a new tertiary hydrogen bond. (1999) (24)
- Release of a disordered domain enhances HspB1 chaperone activity toward tau (2020) (23)
- Structural insights into SAM domain‐mediated tankyrase oligomerization (2016) (22)
- Hydrogen bonding and equilibrium isotope enrichment in histidine-containing proteins (1996) (22)
- The Ubiquitin-Conjugating Enzyme, UbcM2, Is Restricted to Monoubiquitylation by a Two-Fold Mechanism That Involves Backside Residues of E2 and Lys48 of Ubiquitin (2014) (21)
- Structure of a histidine-X4-histidine zinc finger domain: insights into ADR1-UAS1 protein-DNA recognition. (1994) (21)
- Tuning BRCA1 and BARD1 activity to investigate RING ubiquitin ligase mechanisms (2017) (21)
- Interplay of disordered and ordered regions of a human small heat shock protein yields an ensemble of “quasi-ordered” states (2019) (21)
- De novo mutation in RING1 with epigenetic effects on neurodevelopment (2018) (20)
- Identification and Structural Determination of the M3 Muscarinic Acetylcholine Receptor Basolateral Sorting Signal* (2005) (19)
- Structural basis for tankyrase‐RNF146 interaction reveals noncanonical tankyrase‐binding motifs (2018) (19)
- ADR1a, a zinc finger peptide, exists in two folded conformations. (1991) (19)
- [8] Spectroscopic analyses of calmodulin and its interactions (1983) (18)
- Synthesis and structure reassignment of mercaptohistidines of marine origin: syntheses of L-ovothiols A and C (1987) (18)
- Mediator subunit Med15 dictates the conserved “fuzzy” binding mechanism of yeast transcription activators Gal4 and Gcn4 (2019) (18)
- NMR chemical shift perturbation mapping of dna binding by a zinc‐finger domain from the yeast transcription factor ADR1 (1997) (18)
- Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination (2020) (17)
- Structural and kinetic characterization of the simplified SH3 domain FP1 (2003) (16)
- Investigation of a side‐chain‐side‐chain hydrogen bond by mutagenesis, thermodynamics, and NMR spectroscopy (1995) (16)
- Who with whom: functional coordination of E2 enzymes by RING E3 ligases during poly‐ubiquitylation (2020) (16)
- The whole is not the simple sum of its parts in calmodulin from S. cerevisiae. (2000) (16)
- Mechanistic insights revealed by a UBE2A mutation linked to intellectual disability (2018) (15)
- The structure of HPr and site-directed mutagenesis. (1989) (15)
- MyoD forms micelles which can dissociate to form heterodimers with E47: implications of micellization on function. (1995) (14)
- Sequence‐Specific DNA Recognition by Cys2, His2 Zinc Fingers a (1994) (14)
- Interplay of disordered and ordered regions of a human small heat shock protein yields an ensemble of ‘quasi-ordered’ states (2019) (14)
- Biochemical and Structural Characterization of the Ubiquitin-Conjugating Enzyme UBE2W Reveals the Formation of a Noncovalent Homodimer (2013) (14)
- E 2 ~ Ub conjugates regulate kinase activity of the Shigella effector OspG during pathogenesis (2013) (14)
- The BRCA1/BARD1 ubiquitin ligase and its substrates. (2021) (13)
- Infantile onset spinocerebellar ataxia caused by compound heterozygosity for Twinkle mutations and modeling of Twinkle mutations causing recessive disease (2016) (13)
- Peeking from behind the veil of enigma: emerging insights on small heat shock protein structure and function (2020) (13)
- Structural Biology: Parkin’s Serpentine Shape Revealed in the Year of the Snake (2013) (13)
- HSPB5 engages multiple states of a destabilized client to enhance chaperone activity in a stress-dependent manner (2018) (12)
- A Simple Method for the Refinement of Models Derived from NMR Data Demonstrated on a Zinc-Finger Domain from Yeast ADR1 (1993) (12)
- Characterization of RING-Between-RING E3 Ubiquitin Transfer Mechanisms. (2018) (12)
- Flavonoid Regulation of HCN2 Channels* (2013) (12)
- RING‐between‐RINGs—keeping the safety on loaded guns (2012) (11)
- Cbl interacts with multiple E2s in vitro and in cells (2019) (11)
- Hydrogen Bond Geometry and 2 H/ 1 H Fractionation in Proteins (2000) (11)
- Solution structure of sperm lysin yields novel insights into molecular dynamics of rapid protein evolution (2017) (11)
- Paramagnetic cobalt as a probe of the orientation of an accessory DNA-binding region of the yeast ADR1 zinc-finger protein. (1997) (11)
- Proton nuclear magnetic resonance studies on the variant-3 neurotoxin from Centruroides sculpturatus Ewing: sequential assignment of resonances. (1989) (9)
- The mobility of calcium-trigger proteins and its function. (2008) (9)
- Proton nuclear magnetic resonance characterization of the aromatic residues in the variant-3 neurotoxin from Centruroides sculpturatus Ewing. (1989) (8)
- Two-dimensional 1H NMR studies of histidine-containing protein from Escherichia coli. 3. Secondary and tertiary structure as determined by NMR. (1986) (7)
- Multidimensional nuclear magnetic resonance spectroscopy of DNA-binding proteins. (1991) (7)
- Solvent Exchange Rates of Side-chain Amide Protons in Proteins (1998) (7)
- Following Ariadne's thread: a new perspective on RBR ubiquitin ligases (2012) (6)
- RMSD analysis of structures of the bacterial protein FimH identifies five conformations of its lectin domain (2020) (6)
- A native chemical chaperone in the human eye lens (2020) (6)
- pUBLically unzipping Parkin: how phosphorylation exposes a ligase bit by bit (2015) (5)
- 1H NMR Studies of Calmodulin-Peptide Interactions (1987) (5)
- Mechanism of phosphoribosyl-ubiquitination mediated by a single Legionella effector (2018) (5)
- Indirect sexual selection drives rapid sperm protein evolution in abalone (2019) (4)
- Solution Structure of the alpha-crystallin domain from the redox-sensitive chaperone, HSPB1 (2015) (4)
- Spectroscopic analyses of calmodulin and its interactions. (1983) (4)
- The Essential Ubc 4 / Ubc 5 Function in Yeast Is HECT E 3-dependent , and RING E 3-dependent Pathways Require Only Monoubiquitin Transfer by Ubc 4 * (2011) (4)
- UbcH5 interacts with substrates to participate in lysine selection with the E3 ubiquitin ligase CHIP. (2020) (4)
- The ubiquitin ligase SspH1 from Salmonella uses a modular and dynamic E3 domain to catalyze substrate ubiquitylation (2018) (3)
- Toggle switch residues control allosteric transitions in bacterial adhesins by participating in a concerted repacking of the protein core (2021) (3)
- Cullin-independent recognition of HHARI substrates by a dynamic RBR catalytic domain. (2022) (3)
- Transcription activator-coactivator specificity is mediated by a large and dynamic fuzzy protein-protein complex (2017) (2)
- Solution structure of the BRCA1/BARD1 RING-domain heterodimer (2001) (2)
- Study of calmodulin-peptide interactions by NMR spectroscopy. (1987) (2)
- BRCA1/BARD1 is a nucleosome reader and writer. (2022) (2)
- Conservation of transcriptional regulation by BRCA1 and BARD1 in Caenorhabditis elegans (2022) (2)
- pH-dependent structural modulation is conserved in the human small heat shock protein HSBP1 (2017) (2)
- S–100: A CALCIUM-TRIGGER PROTEIN (1981) (2)
- Abstract 4542: Ube2d family members, Ube2e family members and Ube2w modulate the ubiquitination and degradation of EGFR by Cbl (2016) (1)
- BRCA1/BARD1 intrinsically disordered regions facilitate chromatin recruitment and ubiquitylation (2023) (1)
- ORGANIZATION OF MYOSIN LIGHT CHAIN KINASE FROM RABBIT SKELETAL MUSCLE (1987) (1)
- Author response: A conserved histidine modulates HSPB5 structure to trigger chaperone activity in response to stress-related acidosis (2015) (1)
- Backbone 1H, 13C, and 15N Resonance Assignment of the 46 kDa Dimeric GAF A Domain of Phosphodiesterase 5 (2005) (1)
- Mapping of Specific Protein-Protein Interactions by NMR (1994) (1)
- The Structure of the GAF A Domain from Phosphodiesterase 6 C Reveals (2008) (1)
- Disordered region encodes α-crystallin chaperone activity toward lens client γD-crystallin. (2023) (1)
- NMR studies of two related phosphotransfer proteins (1991) (1)
- Zinc-finger motifs and DNA binding. (1989) (1)
- Solution Structure of cGMP-binding GAF domain of Phosphodiesterase 5 (2008) (1)
- Abstract 4441: Ube2e inhibits the ubiquitination and degradation of EGFR mediated by Cbl and Ube2d (2014) (1)
- Neutralizing antibodies against allosteric proteins: insights from a bacterial adhesin. (2022) (1)
- The growing world of small heat shock proteins: from structure to functions (2017) (1)
- Chemical shift assignments and structure of the alpha-crystallin domain from human, HSPB5 (2015) (0)
- NMR STRUCTURE OF HISTIDINE PHOSPHORYLATED FORM OF THE PHOSPHOCARRIER HISTIDINE CONTAINING PROTEIN FROM BACILLUS SUBTILIS, NMR, 25 STRUCTURES (1997) (0)
- REFINED NMR STRUCTURE OF PHOSPHOCARRIER HISTIDINE CONTAINING PROTEIN FROM BACILLUS SUBTILIS (1996) (0)
- Peeking from behind the veil of enigma: emerging insights on small heat shock protein structure and function (2020) (0)
- Author response: Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1 (2016) (0)
- Solution structure of the human ubiquitin conjugating enzyme Ube2w (2014) (0)
- Abstract 1719: Activation of human small heat shock protein HSPB5 by zinc: Taking advantage of a multitude of possibilities (2023) (0)
- SODIUM CHANNEL IIA INACTIVATION GATE (1999) (0)
- Crystal Structure of the BRCA1 Associated Ring Domain (BARD1) Tandem BRCT Domains (2008) (0)
- Structure of Shigella effector OspG in complex with host UbcH5c- Ubiquitin conjugate (2014) (0)
- Author response: Indirect sexual selection drives rapid sperm protein evolution in abalone (2019) (0)
- Synthesis and Structure Reassignment of Mercaptohistidines of Marine Origin. Syntheses of L‐Ovothiols A and C. (1988) (0)
- Crystal structure of the cGMP-bound GAF a domain from the photoreceptor phosphodiesterase 6C (2008) (0)
- Structure of the α-crystallin domain from the redox-sensitive chaperone, HSPB1 (2015) (0)
- HSPB5 disease-associated mutations have long-range effects on structure and dynamics through networks of quasi-ordered interactions (2022) (0)
- Cryo-EM structure of the BRCA1-UbcH5c/BARD1 E3-E2 module bound to a nucleosome (2021) (0)
- Determination of Secondary and Tertiary Structures of Proteins in Solution by Two-Dimensional NMR (1987) (0)
- A native chemical chaperone in the human eye lens suppresses redox-dependent lens crystallin misfolding. (2023) (0)
- Solution Structure of the UbcH5c/Ub Non-covalent Complex (2006) (0)
- Complex Structure of the Activation Domain of Gcn4 bound to the Mediator Co-Activator Domain of Gal11/Med15 (2010) (0)
- MyoDformsmicelles whichcandissociate toformheterodimers withE47:Implications ofmicellization onfunction (1995) (0)
- Solid-state NMR structure of the alpha-crystallin domain in alphaB-crystallin oligomers (2010) (0)
- A pH‐dependent Switch Regulates Chaperone Activity (2011) (0)
- Indirect Sexual Selection Drives Rapid Sperm Protein Evolution (2019) (0)
- Disorder, quasi-order, order: a holistic view of small heat shock proteins (2022) (0)
- Sequence-specific DNA recognition by Cys{sub 2}, His{sub 2} zinc fingers (1994) (0)
- Model of a 24mer alphaB-crystallin multimer (2016) (0)
- A COMPARISON OF DIFFERENT PREPARATIONS IF BOVINE BRAIN CALMODULIN (1980) (0)
- Author response: Acidic pH and divalent cation sensing by PhoQ are dispensable for systemic salmonellae virulence (2015) (0)
- Solution structure of yeast Med15 ABD2 residues 277-368 (2018) (0)
- Structural, Functional, and Mechanistic Diversity in Protein Ubiquitination (2015) (0)
- The Disparate Effects of two Molecular Chaperones on Tau Amyloid Formation (2016) (0)
- Mechanism of phosphoryl transfer and protein-protein interaction in the PTS system-an NMR study (1994) (0)
- Abstract 6096: BRCA1-BARD1 ubiquitylates histones for genome maintenance (2023) (0)
- SYNTHESIS AND THERMAL REARRANGEMENT OF 7-(1,2-BUTADIEN-1-YL)BICYCLO(2.2.1)HEPT-2-ENE (7-(3-METHYLALLENYL)NORBORNENE) (1982) (0)
- Activation of UbcH5c~Ub is the result of a shift in inter-domain motions of the conjugate when bound to the U-box E3 ligase E4B (2013) (0)
- UbcH5c~Ubiquitin Conjugate (2012) (0)
- Crystal structure of RNF146(RING-WWE)/UbcH5a/iso-ADPr complex (2014) (0)
- HSPB5 alpha-crystallin domain mutant R120G-ACD (2018) (0)
- 13C and 15N Chemical Shift Assignments for human alphaB-crystallin (2009) (0)
- PDE5 Site A: A Structural Analysis of cGMP Binding (2003) (0)
- Intrinsically-Disordered Region of Human Small Heat Shock Protein HSPB1 Affects Structure and Function (2016) (0)
- Tips for Applying to Graduate School Networking Deciding Where to Go to Graduate School and/or What to Do after College Communication and Interviewing Skills (2019) (0)
- Biochemical and Structural Characterization of the Ubiquitin-Conjugating Enzyme UBE2W Reveals the Formation of a Noncovalent Homodimer (2013) (0)
- Structural and Biophysical Characterization of the GAF Domains from Phosphodiesterases 5 and 6 (2009) (0)
- Structure of the complex of the central activation doamin of Gcn4 bound to the mediator co-activator domain 1 of Gal11/med15 (2012) (0)
- How Do Small Heat Shock Proteins Function? (2009) (0)
- Abstract 2159: Deciphering the Mechanism of Ubiquitin Transfer by the Non-Canonical E2 Conjugating Enzyme, Ubc6 (2023) (0)
- Abstract 4965: Multiple ubiquitin-conjugating enzymes modulate the ubiquitination and downregulation of the EGFR by the Cbl RING finger ubiquitin ligase (2015) (0)
- PROTEINS IN SOLUTION BY TWO-DIMENSIONAL NMR (1987) (0)
- Study of Protein-H2O Interactions by Multidimensional NMR Spectroscopy (1993) (0)
- Small heat shock proteins: multifaceted proteins with important implications for life (2019) (0)
- Two-iendoal NMR inetpinof a bent DNA hwet n n of the proton resonances and prliry stture analysis (0)
- 23 – STUDY OF A PHOSPHORYLATED PROTEIN BY TWO-DIMENSIONAL NMR SPECTROSCOPY1 (1989) (0)
- Author response: Interplay of disordered and ordered regions of a human small heat shock protein yields an ensemble of ‘quasi-ordered’ states (2019) (0)
- Chemical Shift Assignments and Structure of HSPB1_ACD (2015) (0)
- Structure of the M3 Muscarinic Acetylcholine Receptor Basolateral Sorting Signal (2005) (0)
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