Rafael De Cabo
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Rafael De Cabosocial-work Degrees
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#78
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#88
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Gerontology
#36
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#38
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Rafael De Cabobiology Degrees
Biology
#12873
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#16377
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Biochemistry
#2225
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#2371
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Social Work Biology
Rafael De Cabo's Degrees
- PhD Biochemistry University of Buenos Aires
Why Is Rafael De Cabo Influential?
(Suggest an Edit or Addition)Rafael De Cabo's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Calorie Restriction Promotes Mammalian Cell Survival by Inducing the SIRT1 Deacetylase (2004) (1920)
- SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function. (2012) (1271)
- Suppression of Oxidative Stress by β-Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor (2013) (1142)
- Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span. (2008) (1131)
- Metformin improves healthspan and lifespan in mice (2013) (1031)
- Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice. (2011) (800)
- Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie intake (2003) (652)
- Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency. (2006) (636)
- Growth Hormone Receptor Deficiency Is Associated with a Major Reduction in Pro-Aging Signaling, Cancer, and Diabetes in Humans (2011) (631)
- The SIRT1 Deacetylase Suppresses Intestinal Tumorigenesis and Colon Cancer Growth (2008) (606)
- Effects of Intermittent Fasting on Health, Aging, and Disease. (2019) (601)
- Caloric restriction improves health and survival of rhesus monkeys (2017) (550)
- Fasting Cycles Retard Growth of Tumors and Sensitize a Range of Cancer Cell Types to Chemotherapy (2012) (515)
- Mechanisms of vascular aging: new perspectives. (2010) (482)
- Interventions to Slow Aging in Humans: Are We Ready? (2015) (462)
- SIRT1 Is Essential for Normal Cognitive Function and Synaptic Plasticity (2010) (429)
- CORRIGENDUM: SRT1720 improves survival and healthspan of obese mice (2013) (411)
- The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance. (2015) (409)
- The SIRT1 activator SRT1720 extends lifespan and improves health of mice fed a standard diet. (2014) (319)
- Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice. (2016) (303)
- A time to fast (2018) (278)
- Dietary deprivation extends lifespan in Caenorhabditis elegans (2006) (274)
- Osteocalcin Signaling in Myofibers Is Necessary and Sufficient for Optimum Adaptation to Exercise. (2016) (270)
- A high-fat diet and NAD(+) activate Sirt1 to rescue premature aging in cockayne syndrome. (2014) (268)
- SRT1720 improves survival and healthspan of obese mice (2011) (266)
- JNK1 Phosphorylates SIRT1 and Promotes Its Enzymatic Activity (2009) (261)
- Vasoprotective effects of resveratrol and SIRT1: attenuation of cigarette smoke-induced oxidative stress and proinflammatory phenotypic alterations. (2008) (259)
- Calorie restriction up-regulates the plasma membrane redox system in brain cells and suppresses oxidative stress during aging (2006) (256)
- Measuring biological aging in humans: A quest (2019) (245)
- The Neuromuscular Junction: Aging at the Crossroad between Nerves and Muscle (2014) (243)
- Fasting-Mimicking Diet Reduces HO-1 to Promote T Cell-Mediated Tumor Cytotoxicity. (2016) (232)
- Fumarate Is Cardioprotective via Activation of the Nrf2 Antioxidant Pathway (2012) (232)
- Nrf2 mediates cancer protection but not prolongevity induced by caloric restriction (2008) (217)
- Mechanisms Underlying Caloric Restriction and Lifespan Regulation: Implications for Vascular Aging (2008) (217)
- Resveratrol improves adipose insulin signaling and reduces the inflammatory response in adipose tissue of rhesus monkeys on high-fat, high-sugar diet. (2013) (215)
- Genome-wide identification of microRNAs regulating cholesterol and triglyceride homeostasis (2015) (214)
- Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice. (2018) (210)
- Animal models of aging research: implications for human aging and age-related diseases. (2015) (202)
- SRT2104 extends survival of male mice on a standard diet and preserves bone and muscle mass (2014) (195)
- Alternate Day Fasting Improves Physiological and Molecular Markers of Aging in Healthy, Non-obese Humans. (2019) (192)
- Resveratrol prevents high fat/sucrose diet-induced central arterial wall inflammation and stiffening in nonhuman primates. (2014) (189)
- FOXOs attenuate bone formation by suppressing Wnt signaling. (2013) (187)
- Regulation of SIRT6 protein levels by nutrient availability (2008) (178)
- Evaluation of resveratrol, green tea extract, curcumin, oxaloacetic acid, and medium-chain triglyceride oil on life span of genetically heterogeneous mice. (2013) (177)
- Deletion of the mammalian INDY homolog mimics aspects of dietary restriction and protects against adiposity and insulin resistance in mice. (2011) (175)
- Cockayne syndrome group B protein prevents the accumulation of damaged mitochondria by promoting mitochondrial autophagy (2012) (174)
- Daily Fasting Improves Health and Survival in Male Mice Independent of Diet Composition and Calories. (2019) (172)
- Calorie restriction attenuates Alzheimer's disease type brain amyloidosis in Squirrel monkeys (Saimiri sciureus). (2006) (170)
- Reconsidering the Role of Mitochondria in Aging. (2015) (170)
- Ubiquitin‐mediated proteolysis of HuR by heat shock (2009) (161)
- Mode of action of bullatacin, a potent antitumor acetogenin: inhibition of NADH oxidase activity of HeLa and HL-60, but not liver, plasma membranes. (1994) (151)
- Dietary Protein to Carbohydrate Ratio and Caloric Restriction: Comparing Metabolic Outcomes in Mice. (2015) (148)
- HuR and GRSF1 modulate the nuclear export and mitochondrial localization of the lncRNA RMRP (2016) (147)
- The importance of plasma membrane coenzyme Q in aging and stress responses. (2007) (147)
- Old Age and the Hepatic Sinusoid (2008) (147)
- MicroRNA 33 Regulates Glucose Metabolism (2013) (141)
- miR-519 suppresses tumor growth by reducing HuR levels (2010) (134)
- Vitamin E and selenium deficiency induces expression of the ubiquinone‐dependent antioxidant system at the plasma membrane (1998) (131)
- Inhibition of Breast Cancer Metastasis by Resveratrol-Mediated Inactivation of Tumor-Evoked Regulatory B Cells (2013) (127)
- Metformin‐mediated increase in DICER1 regulates microRNA expression and cellular senescence (2016) (126)
- Resveratrol Prevents β-Cell Dedifferentiation in Nonhuman Primates Given a High-Fat/High-Sugar Diet (2013) (124)
- A Regulatory Role for MicroRNA 33* in Controlling Lipid Metabolism Gene Expression (2013) (123)
- Negative Regulation of STAT3 Protein-mediated Cellular Respiration by SIRT1 Protein* (2011) (119)
- Chronic ingestion of 2-deoxy-D-glucose induces cardiac vacuolization and increases mortality in rats. (2010) (111)
- Capsaicin inhibits plasma membrane NADH oxidase and growth of human and mouse melanoma lines. (1996) (111)
- Macronutrients and caloric intake in health and longevity. (2015) (110)
- Sirtuin1 (Sirt1) Promotes Cortical Bone Formation by Preventing β-Catenin Sequestration by FoxO Transcription Factors in Osteoblast Progenitors* (2014) (108)
- Impact of Longevity Interventions on a Validated Mouse Clinical Frailty Index. (2016) (108)
- SIRT1 but not its increased expression is essential for lifespan extension in caloric-restricted mice (2013) (107)
- Moving Frailty Toward Clinical Practice: NIA Intramural Frailty Science Symposium Summary (2019) (107)
- Mitochondrial Protection by Resveratrol (2011) (106)
- Metformin: A Hopeful Promise in Aging Research. (2016) (103)
- Age-associated miRNA Alterations in Skeletal Muscle from Rhesus Monkeys reversed by caloric restriction (2013) (102)
- Dietary interventions to extend life span and health span based on calorie restriction. (2010) (102)
- RAP1 Protects from Obesity through Its Extratelomeric Role Regulating Gene Expression (2013) (101)
- RNA-binding protein HuD controls insulin translation. (2012) (99)
- Perinatal exercise improves glucose homeostasis in adult offspring. (2012) (97)
- Maternal exercise improves insulin sensitivity in mature rat offspring. (2013) (97)
- Commensal bacteria contribute to insulin resistance in aging by activating innate B1a cells (2018) (93)
- Mitochondrial metabolic reprogramming induced by calorie restriction. (2013) (93)
- Nrf2 Deficiency Exacerbates Obesity-Induced Oxidative Stress, Neurovascular Dysfunction, Blood–Brain Barrier Disruption, Neuroinflammation, Amyloidogenic Gene Expression, and Cognitive Decline in Mice, Mimicking the Aging Phenotype (2018) (92)
- Circular RNAs in monkey muscle: age-dependent changes (2015) (91)
- HuD regulates coding and noncoding RNA to induce APP→Aβ processing. (2014) (89)
- Skeletal muscle ex vivo mitochondrial respiration parallels decline in vivo oxidative capacity, cardiorespiratory fitness, and muscle strength: The Baltimore Longitudinal Study of Aging (2018) (87)
- Oxidative Stress Accumulates in Adipose Tissue during Aging and Inhibits Adipogenesis (2011) (86)
- The Effects of Aging and Sex Steroid Deficiency on the Murine Skeleton Are Independent and Mechanistically Distinct (2017) (86)
- Effects of calorie restriction on cardioprotection and cardiovascular health. (2011) (82)
- Comparing the Effects of Low-Protein and High-Carbohydrate Diets and Caloric Restriction on Brain Aging in Mice (2018) (80)
- Sirtuin1 Suppresses Osteoclastogenesis by Deacetylating FoxOs. (2015) (79)
- Pharmacological inhibition of PI3K reduces adiposity and metabolic syndrome in obese mice and rhesus monkeys. (2015) (77)
- Cognitive and behavioral evaluation of nutritional interventions in rodent models of brain aging and dementia (2017) (75)
- Genetic Ablation of miR-33 Increases Food Intake, Enhances Adipose Tissue Expansion, and Promotes Obesity and Insulin Resistance (2018) (74)
- Measures of Healthspan as Indices of Aging in Mice-A Recommendation. (2016) (71)
- In Vitro Cellular Adaptations of Indicators of Longevity in Response to Treatment with Serum Collected from Humans on Calorie Restricted Diets (2008) (71)
- Dietary restriction: standing up for sirtuins. (2010) (70)
- AsSIRTing the DNA damage response. (2008) (68)
- Ceramide-dependent Caspase 3 Activation is Prevented by Coenzyme Q from Plasma Membrane in Serum-deprived Cells (2002) (68)
- The carbohydrate-insulin model: a physiological perspective on the obesity pandemic (2021) (68)
- Protective role of ubiquinone in vitamin E and selenium‐deficient plasma membranes (1999) (62)
- Aging biology and novel targets for drug discovery. (2012) (61)
- GH Receptor Deficiency in Ecuadorian Adults Is Associated With Obesity and Enhanced Insulin Sensitivity. (2015) (57)
- Age-induced accumulation of methylmalonic acid promotes tumour progression (2020) (57)
- The road ahead for health and lifespan interventions (2020) (56)
- A roadmap to build a phenotypic metric of ageing: insights from the Baltimore Longitudinal Study of Aging (2020) (54)
- A toolbox for the longitudinal assessment of healthspan in aging mice (2020) (54)
- Conserved and Differential Effects of Dietary Energy Intake on the Hippocampal Transcriptomes of Females and Males (2008) (54)
- Pharmacological Strategies to Retard Cardiovascular Aging. (2016) (54)
- Restoration of energy homeostasis by SIRT6 extends healthy lifespan (2021) (53)
- Cytochrome b5 reductase and the control of lipid metabolism and healthspan (2016) (53)
- Adverse Geriatric Outcomes Secondary to Polypharmacy in a Mouse Model: The Influence of Aging. (2016) (52)
- Untangling Determinants of Enhanced Health and Lifespan through a Multi-omics Approach in Mice. (2020) (52)
- Ultrastructure of the liver microcirculation influences hepatic and systemic insulin activity and provides a mechanism for age‐related insulin resistance (2016) (52)
- miR-27b inhibits LDLR and ABCA1 expression but does not influence plasma and hepatic lipid levels in mice. (2015) (51)
- Effect of Resveratrol on Walking Performance in Older People With Peripheral Artery Disease: The RESTORE Randomized Clinical Trial (2017) (51)
- Novel RNA-binding activity of MYF5 enhances Ccnd1/Cyclin D1 mRNA translation during myogenesis (2016) (48)
- Caloric Restriction Study Design Limitations in Rodent and Nonhuman Primate Studies (2017) (47)
- Resveratrol supplementation confers neuroprotection in cortical brain tissue of nonhuman primates fed a high-fat/sucrose diet (2016) (47)
- Of Greek heroes, wiggling worms, mighty mice, and old body builders. (2012) (46)
- Liver aging and pseudocapillarization in a Werner syndrome mouse model. (2014) (46)
- Cell Survival from Chemotherapy Depends on NF-κB Transcriptional Up-Regulation of Coenzyme Q Biosynthesis (2009) (44)
- A protein disulfide-thiol interchange activity of HeLa plasma membranes inhibited by the antitumor sulfonylurea N-(4-methylphenylsulfonyl)-N'-(4-chlorophenyl) urea (LY181984) (1997) (44)
- Animal models of frailty: current applications in clinical research (2016) (41)
- NQR1 controls lifespan by regulating the promotion of respiratory metabolism in yeast (2009) (41)
- Identification of miR-148a as a novel regulator of cholesterol metabolism (2015) (40)
- Alterations of ultrastructural and fission/fusion markers in hepatocyte mitochondria from mice following calorie restriction with different dietary fats. (2013) (40)
- Auxin-Modulated Protein Disulfide-Thiol-Interchange Activity from Soybean Plasma Membranes (1995) (40)
- NADH and NADPH-dependent reduction of coenzyme Q at the plasma membrane. (2000) (40)
- RNA-Binding Protein AUF1 Promotes Myogenesis by Regulating MEF2C Expression Levels (2014) (39)
- Age‐Related Changes in the Liver Sinusoidal Endothelium (2007) (38)
- A comparative study of matrix remodeling in chronic models for COPD; mechanistic insights into the role of TNF-α. (2014) (38)
- Hexokinases link DJ-1 to the PINK1/parkin pathway (2017) (37)
- Disulfiram Treatment Normalizes Body Weight in Obese Mice. (2020) (36)
- Health benefits of late-onset metformin treatment every other week in mice (2017) (36)
- Alternate Day Fasting Improves Physiological and Molecular Markers of Aging in Healthy, Non-obese Humans. (2020) (36)
- AGE AND CALORIC RESTRICTION DIETS ARE CONFOUNDING FACTORS THAT MODIFY THE RESPONSE TO LIPOPOLYSACCHARIDE BY PERITONEAL MACROPHAGES IN C57BL/6 MICE (2004) (36)
- Estrogens decrease osteoclast number by attenuating mitochondria oxidative phosphorylation and ATP production in early osteoclast precursors (2020) (33)
- Overexpression of CYB5R3 and NQO1, two NAD +‐producing enzymes, mimics aspects of caloric restriction (2018) (33)
- Genetic deletion of Nrf2 promotes immortalization and decreases life span of murine embryonic fibroblasts. (2011) (33)
- Age-related pseudocapillarization of the liver sinusoidal endothelium impairs the hepatic clearance of acetaminophen in rats. (2011) (33)
- Time-restricted feeding (TRF) for prevention of age-related vascular cognitive impairment and dementia (2020) (32)
- α‐Motor neurons are spared from aging while their synaptic inputs degenerate in monkeys and mice (2018) (32)
- Caloric restriction modulates insulin receptor signaling in liver and skeletal muscle of rat. (2005) (31)
- Redox modulation of NQO1 (2018) (31)
- A patent review of sirtuin activators: an update (2012) (29)
- Chronic polypharmacy with increasing Drug Burden Index (DBI) exacerbates frailty and impairs physical function, with effects attenuated by deprescribing, in aged mice. (2020) (29)
- Kaempferol increases levels of coenzyme Q in kidney cells and serves as a biosynthetic ring precursor (2017) (29)
- Membrane-bound CYB5R3 is a common effector of nutritional and oxidative stress response through FOXO3a and Nrf2. (2014) (28)
- A cross-sectional study of functional and metabolic changes during aging through the lifespan in male mice (2021) (28)
- Down regulation of miR-124 in both Werner syndrome DNA helicase mutant mice and mutant Caenorhabditis elegans wrn-1 reveals the importance of this microRNA in accelerated aging (2012) (28)
- Hepatic HuR modulates lipid homeostasis in response to high-fat diet (2020) (28)
- Novel RNA-binding activity of NQO1 promotes SERPINA1 mRNA translation. (2016) (27)
- Intermittent Fasting: From Calories to Time Restriction (2021) (27)
- CYB5R3: a key player in aerobic metabolism and aging? (2009) (26)
- The arcuate nucleus and neuropeptide Y contribute to the antitumorigenic effect of calorie restriction (2011) (26)
- A rat epigenetic clock recapitulates phenotypic aging and co-localizes with heterochromatin (2020) (26)
- Energy Restriction and Colorectal Cancer: A Call for Additional Research (2020) (26)
- Survival transcriptome in the coenzyme Q10 deficiency syndrome is acquired by epigenetic modifications: a modelling study for human coenzyme Q10 deficiencies (2013) (25)
- ARDD 2020: from aging mechanisms to interventions (2020) (25)
- ADCK2 Haploinsufficiency Reduces Mitochondrial Lipid Oxidation and Causes Myopathy Associated with CoQ Deficiency (2019) (24)
- SIRT1 Polymorphisms and Serum-Induced SIRT1 Protein Expression in Aging and Frailty: The CHAMP Study (2017) (24)
- A Comparison of Two Mouse Frailty Assessment Tools (2017) (24)
- Caloric Restriction Research: New Perspectives on the Biology of Aging. (2017) (24)
- Muscle-Specific Myosin Heavy Chain Shifts in Response to a Long-Term High Fat/High Sugar Diet and Resveratrol Treatment in Nonhuman Primates (2016) (23)
- The evolution of research on ageing and nutrition. (2014) (22)
- Age-induced methylmalonic acid accumulation promotes tumor progression (2020) (22)
- Breaking the Ceiling of Human Maximal Life span (2018) (22)
- Serum from calorie-restricted animals delays senescence and extends the lifespan of normal human fibroblasts in vitro (2015) (22)
- Amniotic Epithelial Cells: A New Tool to Combat Aging and Age-Related Diseases? (2016) (21)
- Of aging mice and men: gait speed decline is a translatable trait, with species-specific underlying properties. (2019) (21)
- Daily caloric restriction limits tumor growth more effectively than caloric cycling regardless of dietary composition (2021) (21)
- Conserved and species-specific molecular denominators in mammalian skeletal muscle aging (2017) (21)
- Determinants of serum-induced SIRT1 expression in older men: the CHAMP study. (2011) (21)
- Study of Longitudinal Aging in Mice: Presentation of Experimental Techniques (SLAM POET). (2020) (21)
- Kynurenines link chronic inflammation to functional decline and physical frailty (2020) (21)
- Aging, drugs, and drug metabolism. (2012) (21)
- Future directions of resveratrol research (2018) (20)
- Calorie Restriction Curbs Proinflammation That Accompanies Arterial Aging, Preserving a Youthful Phenotype (2018) (20)
- Factors that Impact on Interrater Reliability of the Mouse Clinical Frailty Index. (2015) (20)
- The effect of aging on acetaminophen pharmacokinetics, toxicity and Nrf2 in Fischer 344 rats. (2014) (18)
- Conditioned medium derived from rat amniotic epithelial cells confers protection against inflammation, cancer, and senescence (2016) (18)
- Long-term Dietary Macronutrients and Hepatic Gene Expression in Aging Mice (2018) (17)
- The Impact of Aging, Calorie Restriction and Dietary Fat on Autophagy Markers and Mitochondrial Ultrastructure and Dynamics in Mouse Skeletal Muscle. (2018) (17)
- Identifying Biomarkers for Biological Age: Geroscience and the ICFSR Task Force (2021) (17)
- Dietary fat composition influences glomerular and proximal convoluted tubule cell structure and autophagic processes in kidneys from calorie‐restricted mice (2016) (17)
- Metabolic remodelling of glucose, fatty acid and redox pathways in the heart of type 2 diabetic mice (2018) (17)
- Sirt1 protects from K‐Ras‐driven lung carcinogenesis (2018) (16)
- Benefits of Caloric Restriction in Longevity and Chemical-Induced Tumorigenesis Are Transmitted Independent of NQO1 (2019) (16)
- Longitudinal analysis of calorie restriction on rat taste bud morphology and expression of sweet taste modulators. (2014) (16)
- Dietary fat and aging modulate apoptotic signaling in liver of calorie-restricted mice. (2015) (16)
- In vitro caloric restriction induces protective genes and functional rejuvenation in senescent SAMP8 astrocytes (2015) (16)
- ATP Synthase K+- and H+-Fluxes Drive ATP Synthesis and Enable Mitochondrial K+-"Uniporter" Function: I. Characterization of Ion Fluxes. (2021) (15)
- Fasting-mimicking diet prevents high-fat diet effect on cardiometabolic risk and lifespan (2021) (15)
- NQO1 protects obese mice through improvements in glucose and lipid metabolism (2020) (14)
- Deletion of Nrf2 shortens lifespan in C57BL6/J male mice but does not alter the health and survival benefits of caloric restriction. (2020) (14)
- ATP synthase K+- and H+-flux drive ATP synthesis and enable mitochondrial K+-uniporter function (2018) (14)
- Models and Studies of Aging: Executive Summary of a Report from the U13 Conference Series (2019) (14)
- Fasting blood glucose as a predictor of mortality: Lost in translation. (2021) (13)
- ATP Synthase K+- and H+-fluxes Drive ATP Synthesis and Enable Mitochondrial K+-"Uniporter" Function: II. Ion and ATP Synthase Flux Regulation. (2022) (13)
- Spermidine to the rescue for an aging heart (2016) (13)
- Pomalidomide Reduces Ischemic Brain Injury in Rodents (2019) (13)
- Mitochondrial health is enhanced in rats with higher vs. lower intrinsic exercise capacity and extended lifespan (2021) (13)
- Involvement of c‐Jun N‐Terminal Kinase in TNF‐&agr;‐Driven Remodeling (2017) (13)
- Effects of Intermittent Fasting on Health, Aging, and Disease. Reply. (2020) (12)
- Aged interleukin-10tm1Cgn chronically inflamed mice have substantially reduced fat mass, metabolic rate, and adipokines (2017) (12)
- Stem Cell Transplantation for Frailty. (2017) (12)
- 17α-estradiol attenuates neuron loss in ovariectomized Dtg AβPP/PS1 mice. (2011) (12)
- Sirtuin activation: a role for plasma membrane in the cell growth puzzle. (2013) (12)
- Osteocalcin Signaling in Myofibers Is Necessary and Sufficient for Optimum Adaptation to Exercise. (2017) (12)
- A redox-mediated conformational change in NQO1 controls binding to microtubules and α-tubulin acetylation (2020) (11)
- Chronic Exposure to Cadmium Induces Differential Methylation in Mice Spermatozoa. (2021) (10)
- An unSIRTain role in longevity (2011) (10)
- Intermittent mTOR Inhibition Reverses Kidney Aging in Old Rats. (2018) (10)
- Combining a high dose of metformin with the SIRT1 activator, SRT1720, reduces lifespan in aged mice fed a high-fat diet. (2020) (10)
- SIRT1 synchs satellite cell metabolism with stem cell fate. (2015) (10)
- Age-related loss of responsiveness to 2,5-dimethoxy-4-iodoamphetamine in liver sinusoidal endothelial cells. (2014) (9)
- Comparative proteomic analyses of the parietal lobe from rhesus monkeys fed a high-fat/sugar diet with and without resveratrol supplementation, relative to a healthy diet: Insights into the roles of unhealthy diets and resveratrol on function. (2017) (9)
- A Central Role for the Gasotransmitter H2S in Aging. (2020) (9)
- Sex and Aging. (2018) (9)
- The longevity gene mIndy (I’m Not Dead, Yet) affects blood pressure through sympathoadrenal mechanisms (2021) (9)
- Are glycans the Holy Grail for biomarkers of aging? (2014) (9)
- Response of a protein disulfide isomerase-like activity of transitional endoplasmic reticulum to all-trans retinol. (1996) (9)
- The Influence of Old Age and Poloxamer-407 on the Hepatic Disposition of Diazepam in the Isolated Perfused Rat Liver (2012) (9)
- Central nervous system SIRT1 expression is required for cued and contextual fear conditioning memory responses in aging mice (2019) (8)
- Loss of miR-451a enhances SPARC production during myogenesis (2019) (8)
- Maternally expressed gene 3 in metabolic programming. (2020) (8)
- Mitochondrial permeabilization without caspase activation mediates the increase of basal apoptosis in cells lacking Nrf2. (2016) (8)
- Cyclic AMP-plus ATP-dependent modulation of the NADH oxidase activity of porcine liver plasma membranes. (1994) (8)
- Utilizing calorie restriction to evaluate the role of sirtuins in healthspan and lifespan of mice. (2013) (8)
- Aged Nrf2-Null Mice Develop All Major Types of Age-Related Cataracts (2021) (8)
- A toast to your health, one drink at a time. (2010) (7)
- Dietary compliance among salt-sensitive and salt-insensitive normotensive adults. (1999) (7)
- Science-Driven Nutritional Interventions for the Prevention and Treatment of Cancer. (2022) (7)
- Caloric restriction induces heat shock response and inhibits B16F10 cell tumorigenesis both in vitro and in vivo (2015) (6)
- Polypharmacy Results in Functional Impairment in Mice: Novel Insights into Age and Sex Interactions. (2021) (6)
- Yo-yo dieting is better than none (2018) (6)
- Comparing the Effects of Low-Protein and High-Carbohydrate Diets and Caloric Restriction on Brain Aging in Mice (2020) (6)
- Perinatal diet influences health and survival in a mouse model of leukemia (2020) (5)
- A BDNF-TrkB autocrine loop enhances senescent cell viability (2022) (5)
- Sex‐ and strain‐specific effects of mitochondrial uncoupling on age‐related metabolic diseases in high‐fat diet‐fed mice (2022) (5)
- Longitudinal phenotypic aging metrics in the Baltimore Longitudinal Study of Aging (2022) (5)
- Diet composition influences the metabolic benefits of short cycles of very low caloric intake (2021) (5)
- 17α-Estradiol: A Novel Therapeutic Intervention to Target Age-related Chronic Inflammation. (2017) (4)
- Deletion of the diabetes candidate gene Slc16a13 in mice attenuates diet-induced ectopic lipid accumulation and insulin resistance (2021) (4)
- Elucidating the mechanisms by which disulfiram protects against obesity and metabolic syndrome (2020) (4)
- Elucidating the mechanisms by which disulfiram protects against obesity and metabolic syndrome (2020) (3)
- Emergence of heartbeat frailty in advanced age I: perspectives from life-long EKG recordings in adult mice (2022) (3)
- "AcCoA"lade for energy and life span. (2009) (3)
- Metabolic pathways and therapeutics to promote resilience, rehabilitation and delayed aging (2021) (3)
- Short-term senolytic treatment: a paradigm to promote fracture repair during aging (2022) (3)
- The effect of resveratrol on lifespan depends on both gender and dietary nutrient composition in Drosophila melanogaster (2011) (2)
- Resveratrol Blunts Mitochondrial Loss in Slow and Mixed Skeletal Muscle Phenotypes of Non-Human Primates following a Long-Term High Fat/Sugar Diet. (2022) (2)
- Evidence that overnight fasting could extend healthy lifespan (2021) (2)
- Does diet influence aging? Evidence from animal studies. (2022) (2)
- Empirical versus theoretical power and type I error (false-positive) rates estimated from real murine aging research data (2021) (2)
- Interaction of obesity and Nrf2 deficiency accelerates cerebromicrovascular aging and impairs neurovascular coupling responses (2017) (2)
- A specialized metabolic pathway partitions citrate in hydroxyapatite to impact mineralization of bones and teeth (2022) (2)
- Impact of large granular lymphocyte leukemia on blood DNA methylation and epigenetic clock modeling in Fischer 344 rats. (2021) (2)
- FAD-deficient P187S mutation of NAD(P)H:quinone oxidoreductase 1 (NQO1*2) binds and accelerates β-amyloid aggregation (2022) (1)
- The plasma membrane redox enzyme NQO1 sustains cellular energetics and protects human neuroblastoma cells against metabolic and proteotoxic stress (2011) (1)
- Cyb5r3-based mechanism and reversal of secondary failure to sulfonylurea (2022) (1)
- Redox state and the sirtuin deacetylases are major factors that regulate the acetylation status of the stress protein NQO1 (2022) (1)
- The impact of low-protein high-carbohydrate diets on aging and lifespan (2015) (1)
- Mitochondrial adaptations in liver and skeletal muscle to pro-longevity nutritional and genetic interventions: the crosstalk between calorie restriction and CYB5R3 overexpression in transgenic mice (2020) (1)
- Can we make drug discovery targeting fundamental mechanisms of aging a reality? (2021) (1)
- RNA-Binding Protein HuD Controls Insulin Translation. (2020) (1)
- The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group (2021) (1)
- A small erythropoietin derived non-hematopoietic peptide reduces cardiac inflammation, attenuates age associated declines in heart function and prolongs healthspan (2023) (1)
- A remarkable adaptive paradigm of heart performance and protection emerges in response to marked cardiac-specific overexpression of ADCY8 (2022) (1)
- A Glance Back at the Journal of Gerontology-Coffee, Dietary Interventions and Life Span. (2020) (1)
- Energy - A Hallmark of Physical Function. (2015) (1)
- Uncovering the Molecular Underpinnings of Oxidative Stress-Induced Senescence (2020) (0)
- CYB5R3 overexpression preserves skeletal muscle mitochondria and autophagic signaling in aged transgenic mice (2022) (0)
- Publisher Correction: Deletion of the diabetes candidate gene Slc16a13 in mice attenuates diet-induced ectopic lipid accumulation and insulin resistance (2021) (0)
- DPP4 inhibition impairs senohemostasis to improve plaque stability in atherosclerotic mice. (2023) (0)
- Impairing Senohemostasis by Ablating DPP4 Improves Atherosclerosis (2022) (0)
- Two-Year Trial of Human Caloric Restriction. (2015) (0)
- A toolbox for the longitudinal assessment of healthspan in aging mice (2020) (0)
- Hepatic HuR modulates lipid homeostasis in response to high-fat diet (2020) (0)
- A rat epigenetic clock recapitulates phenotypic aging and co-localizes with heterochromatin-associated histone modifications (2020) (0)
- Age-dependent impact of two exercise training regimens on genomic and metabolic remodeling in skeletal muscle and liver of male mice (2022) (0)
- Author response: A rat epigenetic clock recapitulates phenotypic aging and co-localizes with heterochromatin (2020) (0)
- Unraveling Pathways of Health and Lifespan with Integrated Multiomics Approaches. (2022) (0)
- Differences in Longitudinal Fasting Blood Glucose and Mortality Risk Across the Lifespan Between Mice and Humans (2020) (0)
- Age-induced methylmalonic acid accumulation promotes tumor progression and aggressiveness (2020) (0)
- Mitochondrial health is enhanced in rats with higher vs. lower intrinsic exercise capacity and extended lifespan (2021) (0)
- Age-dependent impact of two exercise training regimens on genomic and metabolic remodeling in skeletal muscle and liver of male mice (2022) (0)
- Sex Differences in Response to Metformin in a Longitudinal Study in Mice (2020) (0)
- Reply to A Drewnowski et al, O Devinsky, D A Booth and E L Gibson, and D J Millward. (2022) (0)
- Author Correction: A BDNF-TrkB autocrine loop enhances senescent cell viability (2022) (0)
- Time-Restricted Feeding and Caloric Restriction Impact on Spontaneous Neoplasms in Female Mice (2020) (0)
- 4:10 Cycles of Very Low Calories Protect Against Tumor Xenografts, but Not Metastases in the Absence of Chemotherapy (2020) (0)
- Hexokinases link DJ-1 to the PINK1/parkin pathway (2017) (0)
- Age-induced accumulation of methylmalonic acid promotes tumour progression (2020) (0)
- NQO1 protects obese mice through improvements in glucose and lipid metabolism (2020) (0)
- Publisher Correction: Deletion of the diabetes candidate gene Slc16a13 in mice attenuates diet-induced ectopic lipid accumulation and insulin resistance (2021) (0)
- A hyper-quiescent chromatin state formed during aging is reversed by regeneration (2023) (0)
- The YAP-TEAD complex promotes senescent cell survival by lowering endoplasmic reticulum stress (2022) (0)
- Uncovering the Specific Functions of miR-33 in Regulation of Feeding and Cardiometabolic Diseases Linked to Aging (2020) (0)
- Health benefits of late-onset metformin treatment every other week in mice (2017) (0)
- Longitudinal Fasting Blood Glucose Trends and Mortality Risk in Mice Differs From That of Non-Human Primates and Humans (2020) (0)
- Spontaneous chordoma: a case report on a female UM-HET3 mouse from the SLAM study. (2020) (0)
- [The activity of protein catabolism in diabetes]. (1963) (0)
- Dietary fat modifies mitochondrial and plasma membrane apoptotic signaling in skeletal muscle of calorie-restricted mice (2012) (0)
- Serum concentrations of losartan metabolites correlate with improved physical function in a pilot study of prefrail older adults. (2022) (0)
- A hyper-quiescent chromatin state formed during aging is reversed by regeneration. (2023) (0)
- Conserved and species-specific molecular denominators in mammalian skeletal muscle aging (2017) (0)
- Deletion of the diabetes candidate gene Slc16a13 in mice attenuates diet-induced ectopic lipid accumulation and insulin resistance (2021) (0)
- Calorie Restriction Rescues Mitochondrial Dysfunction in Adck2-Deficient Skeletal Muscle (2022) (0)
- Author response: A cross-sectional study of functional and metabolic changes during aging through the lifespan in male mice (2021) (0)
- Effect of calorie restriction and refeeding on skin wound healing in the rat (2011) (0)
- The influence of dietary fat source on liver and skeletal muscle mitochondrial modifications and lifespan changes in calorie-restricted mice (2015) (0)
- AGEING AND CALORIC RESTRICTED DIET ARE CONFOUNDING FACTORS THAT ALTER THE RESPONSE TO LPS BY PERITONEAL MACROPHAGES FROM C57BL/6 MICE.: 75 (2003) (0)
- Replenishment of myeloid-derived suppressor cells (MDSCs) overrides CR-mediated protection against tumor growth in a murine model of triple-negative breast cancer. (2022) (0)
- Perinatal diet influences health and survival in a mouse model of leukemia (2020) (0)
- Erratum to: Effect of calorie restriction and refeeding on skin wound healing in rats (2011) (0)
- Preclinical and translational models for delirium: Recommendations for future research from the NIDUS delirium network. (2023) (0)
- Corrigendum to: The Effect of Aging on Acetaminophen Pharmacokinetics, Toxicity and Nrf2 in Fischer 344 Rats. (2018) (0)
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