Rainer Spanagel
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Rainer Spanagel's Degrees
- PhD Cognitive Neuroscience University of Vienna
- Masters Psychology University of Vienna
- Bachelors Psychology University of Vienna
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(Suggest an Edit or Addition)Rainer Spanagel's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The dopamine hypothesis of reward: past and current status (1999) (971)
- Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1 (1998) (928)
- REVIEW: Behavioural assessment of drug reinforcement and addictive features in rodents: an overview (2006) (608)
- Alcoholism: a systems approach from molecular physiology to addictive behavior. (2009) (604)
- Opposing tonically active endogenous opioid systems modulate the mesolimbic dopaminergic pathway. (1992) (586)
- Neuropharmacology of alcohol addiction (2008) (552)
- The clock gene Per2 influences the glutamatergic system and modulates alcohol consumption (2005) (548)
- The Effects of Opioid Peptides on Dopamine Release in the Nucleus Accumbens: An In Vivo Microdialysis Study (1990) (543)
- The IMAGEN study: reinforcement-related behaviour in normal brain function and psychopathology (2010) (524)
- Stress-Induced Anhedonia in Mice is Associated with Deficits in Forced Swimming and Exploration (2004) (518)
- Opposing tonically active endogenous opioid systems modulate the mesolimbic dopaminergic pathway (1992) (478)
- Correlated gene expression supports synchronous activity in brain networks (2015) (477)
- Cocaine sensitization and reward are under the influence of circadian genes and rhythm (2002) (452)
- Adolescent impulsivity phenotypes characterized by distinct brain networks (2012) (396)
- Regulation of Monoamine Oxidase A by Circadian-Clock Components Implies Clock Influence on Mood (2008) (368)
- Impaired Long-Term Memory and NR2A-Type NMDA Receptor-Dependent Synaptic Plasticity in Mice Lacking c-Fos in the CNS (2003) (352)
- Anti-craving compounds for ethanol: new pharmacological tools to study addictive processes. (1997) (327)
- Cocaine-evoked synaptic plasticity: persistence in the VTA triggers adaptations in the NAc (2009) (327)
- Genetic variation in the PNPLA3 gene is associated with alcoholic liver injury in caucasians (2010) (291)
- Withdrawal phenomena and dependence syndrome after the consumption of "spice gold". (2009) (289)
- Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption (2011) (270)
- Long-term alcohol self-administration with repeated alcohol deprivation phases: an animal model of alcoholism? (1999) (269)
- Acamprosate and alcohol: I. Effects on alcohol intake following alcohol deprivation in the rat. (1996) (268)
- mGluR5 Antagonist MPEP Reduces Ethanol-Seeking and Relapse Behavior (2004) (251)
- Glutamate Receptors on Dopamine Neurons Control the Persistence of Cocaine Seeking (2008) (234)
- Enhanced and Delayed Stress-Induced Alcohol Drinking in Mice Lacking Functional CRH1 Receptors (2002) (219)
- Genome-wide association study of alcohol dependence. (2009) (216)
- Ambiguous-Cue Interpretation is Biased Under Stress- and Depression-Like States in Rats (2010) (201)
- Genetic association of the human corticotropin releasing hormone receptor 1 (CRHR1) with binge drinking and alcohol intake patterns in two independent samples (2006) (197)
- Anxiety: a potential predictor of vulnerability to the initiation of ethanol self-administration in rats (1995) (183)
- Acamprosate: recent findings and future research directions. (2008) (169)
- The Glucocorticoid Receptor as a Potential Target to Reduce Cocaine Abuse (2003) (168)
- Glutamatergic targets for new alcohol medications (2013) (167)
- Stress-induced hyperlocomotion as a confounding factor in anxiety and depression models in mice (2005) (164)
- Translational Magnetic Resonance Spectroscopy Reveals Excessive Central Glutamate Levels During Alcohol Withdrawal in Humans and Rats (2012) (161)
- Alcohol consumption and the body's biological clock. (2005) (161)
- Chronic intake of fermented floral nectar by wild treeshrews (2008) (160)
- The anti-craving compound acamprosate acts as a weak NMDA-receptor antagonist, but modulates NMDA-receptor subunit expression similar to memantine and MK-801 (2001) (159)
- Drugs for relapse prevention of alcoholism: ten years of progress. (2008) (156)
- Reduced sensitivity to reward in CB1 knockout mice (2004) (155)
- Rescue of Infralimbic mGluR2 Deficit Restores Control Over Drug-Seeking Behavior in Alcohol Dependence (2013) (145)
- Stress and alcohol interactions: animal studies and clinical significance (2014) (139)
- A comparative study on alcohol-preferring rat lines: effects of deprivation and stress phases on voluntary alcohol intake. (2003) (138)
- Unconditioned anxiety and social behaviour in two rat lines selectively bred for high and low anxiety-related behaviour (2000) (137)
- Involvement of the AMPA Receptor GluR-C Subunit in Alcohol-Seeking Behavior and Relapse (2006) (137)
- The alcohol deprivation effect model for studying relapse behavior: a comparison between rats and mice. (2014) (136)
- Determinants of Early Alcohol Use In Healthy Adolescents: The Differential Contribution of Neuroimaging and Psychological Factors (2012) (136)
- Effect of acamprosate on magnetic resonance spectroscopy measures of central glutamate in detoxified alcohol-dependent individuals: a randomized controlled experimental medicine study. (2010) (136)
- The role of the NMDA receptor in alcohol relapse: a pharmacological mapping study using the alcohol deprivation effect (2005) (135)
- Influence of age at drinking onset on long-term ethanol self-administration with deprivation and stress phases. (2005) (134)
- Animal models of addiction (2017) (132)
- Mechanisms of disturbed emotion processing and social interaction in borderline personality disorder: state of knowledge and research agenda of the German Clinical Research Unit (2014) (130)
- Largely overlapping neuronal substrates of reactivity to drug, gambling, food and sexual cues: A comprehensive meta-analysis (2016) (129)
- Long-term ethanol self-administration with repeated ethanol deprivation episodes changes ethanol drinking pattern and increases anxiety-related behaviour during ethanol deprivation in rats (1998) (126)
- Pharmacological validation of a new animal model of alcoholism (2000) (125)
- Acamprosate Produces Its Anti-Relapse Effects Via Calcium (2014) (125)
- The Effects of Acamprosate and Neramexane on Cue-Induced Reinstatement of Ethanol-Seeking Behavior in Rat (2005) (123)
- Systematic analysis of glutamatergic neurotransmission genes in alcohol dependence and adolescent risky drinking behavior. (2008) (122)
- Risk taking and the adolescent reward system: a potential common link to substance abuse. (2012) (121)
- Differential gene expression in peripheral blood of patients suffering from post-traumatic stress disorder (2007) (121)
- Effects of opiate antagonist treatment on the alcohol deprivation effect in long-term ethanol-experienced rats (1999) (119)
- Convergent evidence from alcohol-dependent humans and rats for a hyperdopaminergic state in protracted abstinence (2016) (116)
- Evidence for alcohol anti-craving properties of memantine. (1996) (113)
- Effects of the circadian rhythm gene period 1 (per1) on psychosocial stress-induced alcohol drinking. (2011) (113)
- The dopamine D3 receptor plays an essential role in alcohol‐seeking and relapse (2006) (111)
- Addiction Research Consortium: Losing and regaining control over drug intake (ReCoDe)—From trajectories to mechanisms and interventions (2019) (108)
- Recent Animal Models of Alcoholism (2000) (107)
- Rats with congenital learned helplessness respond less to sucrose but show no deficits in activity or learning (2004) (105)
- Modulation of drug-induced sensitization processes by endogenous opioid systems (1995) (105)
- Kappa-opioid receptors and relapse-like drinking in long-term ethanol-experienced rats (2000) (103)
- Losing Control: Excessive Alcohol Seeking after Selective Inactivation of Cue-Responsive Neurons in the Infralimbic Cortex (2015) (102)
- Alcohol Self-administration in Two Rat Lines Selectively Bred for Extremes in Anxiety-related Behavior (2002) (100)
- Time course of acamprosate action on operant ethanol self-administration after ethanol deprivation. (1997) (96)
- Acamprosate and alcohol: II. Effects on alcohol withdrawal in the rat. (1996) (96)
- Involvement of the atrial natriuretic peptide transcription factor GATA4 in alcohol dependence, relapse risk and treatment response to acamprosate (2011) (95)
- Novel uncompetitive N-methyl-D-aspartate (NMDA)-receptor antagonist MRZ 2/579 suppresses ethanol intake in long-term ethanol-experienced rats and generalizes to ethanol cue in drug discrimination procedure. (2000) (95)
- cDNA microarray analysis reveals novel candidate genes expressed in human peripheral blood following exhaustive exercise. (2005) (95)
- Influence of age at drinking onset on the alcohol deprivation effect and stress-induced drinking in female rats (2007) (94)
- Neurocircuitry for modeling drug effects (2012) (93)
- Memantine-induced dopamine release in the prefrontal cortex and striatum of the rat--a pharmacokinetic microdialysis study. (1994) (92)
- Alcohol addiction research: from animal models to clinics. (2003) (92)
- Long lasting changes in morphine‐induced mesolimbic dopamine release after chronic morphine exposure (1993) (91)
- Reward Sensitivity for a Palatable Food Reward Peaks During Pubertal Developmental in Rats (2010) (91)
- Social and structural housing conditions influence the development of a depressive-like phenotype in the learned helplessness paradigm in male mice (2005) (89)
- Conditioning of Opioid Reinforcement: Neuroanatomical and Neurochemical Substrates (1992) (89)
- The Neuronal Nitric Oxide Synthase Gene Is Critically Involved in Neurobehavioral Effects of Alcohol (2002) (88)
- RASGRF2 regulates alcohol-induced reinforcement by influencing mesolimbic dopamine neuron activity and dopamine release (2012) (87)
- Ethanol and N-methyl-D-aspartate receptor complex interactions: a detailed drug discrimination study in the rat (1998) (87)
- Boys do it the right way: Sex-dependent amygdala lateralization during face processing in adolescents (2011) (84)
- Addiction and its brain science. (2005) (82)
- A systems medicine research approach for studying alcohol addiction (2013) (81)
- Identification of the opioid receptor types mediating beta-endorphin-induced alterations in dopamine release in the nucleus accumbens. (1990) (79)
- Modulation of morphine-induced sensitization by endogenous κ opioid systems in the rat (1993) (79)
- New pharmacological treatment strategies for relapse prevention. (2013) (77)
- Endogenous κ-opioid systems in opiate withdrawal: role in aversion and accompanying changes in mesolimbic dopamine release (1994) (75)
- Oxytocin Reduces Alcohol Cue-Reactivity in Alcohol-Dependent Rats and Humans (2017) (74)
- A Novel Elevated Plus-Maze Procedure to Avoid the One-Trial Tolerance Problem (2011) (72)
- Regulation of immune-modulatory genes in left superior temporal cortex of schizophrenia patients: a genome-wide microarray study (2011) (71)
- Glycine Transporter-1 Blockade Leads to Persistently Reduced Relapse-like Alcohol Drinking in Rats (2010) (71)
- Stress- and corticosteroid-induced modulation of the locomotor response to morphine in rats (1999) (69)
- Fractalkine-upregulated milk-fat globule EGF factor-8 protein in cultured rat microglia (2005) (69)
- Incentive Learning Underlying Cocaine-Seeking Requires mGluR5 Receptors Located on Dopamine D1 Receptor-Expressing Neurons (2010) (68)
- Importance of NO/cGMP signalling via cGMP‐dependent protein kinase II for controlling emotionality and neurobehavioural effects of alcohol (2004) (68)
- Cue-induced alcohol-seeking behaviour is reduced by disrupting the reconsolidation of alcohol-related memories (2009) (68)
- PRECLINICAL STUDY: Circadian regulation of central ethanol sensitivity by the mPer2 gene (2009) (67)
- Assessment of neuroleptic-like properties of progesterone (1999) (66)
- Ethanol self-administration and reinstatement of ethanol-seeking behavior in Per1Brdm1 mutant mice (2006) (65)
- Brain-Specific Inactivation of the Crhr1 Gene Inhibits Post-Dependent and Stress-Induced Alcohol Intake, but Does Not Affect Relapse-Like Drinking (2012) (63)
- Cluster and meta‐analyses on factors influencing stress‐induced alcohol drinking and relapse in rodents (2014) (63)
- Association of Protein Phosphatase PPM1G With Alcohol Use Disorder and Brain Activity During Behavioral Control in a Genome-Wide Methylation Analysis. (2015) (62)
- Acamprosate and alcohol: III. Effects on alcohol discrimination in the rat. (1996) (60)
- RESEARCH FOCUS ON COMPULSIVE BEHAVIOUR IN ANIMALS: Compulsive alcohol drinking in rodents (2009) (60)
- An integrated genome research network for studying the genetics of alcohol addiction (2010) (60)
- Neurobehavioral effects of alcohol in AMPA receptor subunit (GluR1) deficient mice (2003) (59)
- The mGluR2/3 Agonist LY379268 Induced Anti-Reinstatement Effects in Rats Exhibiting Addiction-like Behavior (2013) (59)
- Differential role of the nitric oxide pathway on Δ9‐THC‐induced central nervous system effects in the mouse (2001) (57)
- Acamprosate suppresses the expression of morphine-induced sensitization in rats but does not affect heroin self-administration or relapse induced by heroin or stress (1998) (56)
- The anti-craving drug acamprosate reduces c-fos expression in rats undergoing ethanol withdrawal. (1996) (56)
- Effects of d-cycloserine on extinction of mesolimbic cue reactivity in alcoholism: a randomized placebo-controlled trial (2015) (55)
- Stress triggers anhedonia in rats bred for learned helplessness (2010) (55)
- β-Endorphin-induced locomotor stimulation and reinforcement are associated with an increase in dopamine release in the nucleus accumbens (2005) (54)
- Strain differences in the rewarding and dopamine-releasing effects of morphine in rats (2005) (53)
- A Pharmacogenetic Determinant of Mu-Opioid Receptor Antagonist Effects on Alcohol Reward and Consumption: Evidence from Humanized Mice (2015) (53)
- Reduced oxytocin receptor gene expression and binding sites in different brain regions in schizophrenia: A post-mortem study (2016) (53)
- Adverse Social Experiences in Adolescent Rats Result in Enduring Effects on Social Competence, Pain Sensitivity and Endocannabinoid Signaling (2016) (53)
- Inhibition of the Casein-Kinase-1-Epsilon/Delta Prevents Relapse-Like Alcohol Drinking (2012) (52)
- Evidence that nor-binaltorphimine can function as an antagonist at multiple opioid receptor subtypes. (1994) (52)
- D-cycloserine facilitates extinction of conditioned alcohol-seeking behaviour in rats. (2008) (51)
- Rsu1 regulates ethanol consumption in Drosophila and humans (2015) (51)
- Effects of chronic alcohol consumption on the expression of different NR1 splice variants in the brain of AA and ANA lines of rats. (1999) (51)
- Withdrawal Symptoms in a Long-Term Model of Voluntary Alcohol Drinking in Wistar Rats (2000) (49)
- Analysis of genetic variations of protein tyrosine kinase fyn and their association with alcohol dependence in two independent cohorts (2003) (48)
- Microdialysis studies with amantadine and memantine on pharmacokinetics and effects on dopamine turnover. (1995) (48)
- Enhanced Functional Activity of the Cannabinoid Type-1 Receptor Mediates Adolescent Behavior (2015) (47)
- Loss of the serum response factor in the dopamine system leads to hyperactivity (2010) (46)
- Clock genes × stress × reward interactions in alcohol and substance use disorders. (2015) (46)
- Centrally administered oligodeoxynucleotides in rats: occurrence of non-specific effects. (1997) (45)
- The effects of drugs of abuse on clock genes. (2008) (45)
- Efficacy and safety of sodium oxybate in alcohol‐dependent patients with a very high drinking risk level (2018) (44)
- Low μ-Opioid Receptor Status in Alcohol Dependence Identified by Combined Positron Emission Tomography and Post-Mortem Brain Analysis (2017) (44)
- Glutamate Receptors within the Mesolimbic Dopamine System Mediate Alcohol Relapse Behavior (2015) (41)
- Long-term alcohol self-administration and alcohol withdrawal differentially modulate microtubule-associated protein 2 (MAP2) gene expression in the rat brain. (1998) (40)
- Genetic Deletion of Neuronal PPARγ Enhances the Emotional Response to Acute Stress and Exacerbates Anxiety: An Effect Reversed by Rescue of Amygdala PPARγ Function (2016) (40)
- Loss of the Ca2+/calmodulin-dependent protein kinase type IV in dopaminoceptive neurons enhances behavioral effects of cocaine (2008) (40)
- Pharmacological relapse prevention in alcohol dependence: from animal models to clinical trials. (2001) (39)
- Candidate genes for alcohol dependence: animal studies. (2003) (39)
- Activation of Melatonin Receptors Reduces Relapse-Like Alcohol Consumption (2015) (39)
- mPer1 and mPer2 mutant mice show regular spatial and contextual learning in standardized tests for hippocampus-dependent learning (2006) (38)
- Enhanced morphine-induced behavioural effects and dopamine release in the nucleus accumbens in a transgenic mouse model of impaired glucocorticoid (type II) receptor function: influence of long-term treatment with the antidepressant moclobemide (1998) (38)
- The effects of lamotrigine on alcohol seeking and relapse (2007) (37)
- Increased mesolimbic cue-reactivity in carriers of the mu-opioid-receptor gene OPRM1 A118G polymorphism predicts drinking outcome: A functional imaging study in alcohol dependent subjects (2015) (36)
- Cocaine‐induced dopamine overflow within the nucleus accumbens measured by in vivo microdialysis: A meta‐analysis (2008) (36)
- A multiscale cerebral neurochemical connectome of the rat brain (2017) (36)
- Longitudinal Structural and Functional Brain Network Alterations in a Mouse Model of Neuropathic Pain (2018) (36)
- Adolescent peer-rejection persistently alters pain perception and CB1 receptor expression in female rats (2014) (35)
- Oleoylethanolamide dose‐dependently attenuates cocaine‐induced behaviours through a PPARα receptor‐independent mechanism (2013) (35)
- Reduced alcohol intake and reward associated with impaired endocannabinoid signaling in mice with a deletion of the glutamate transporter GLAST (2012) (35)
- Circadian Expression of Clock- and Tumor Suppressor Genes in Human Oral Mucosa (2006) (35)
- Behavioral Neurobiology of Alcohol Addiction (2013) (34)
- Genetic Variation in the Atrial Natriuretic Peptide Transcription Factor GATA4 Modulates Amygdala Responsiveness in Alcohol Dependence (2014) (34)
- Cannabinoid exposure in pubertal rats increases spontaneous ethanol consumption and NMDA receptor associated protein levels. (2011) (34)
- Impairment of cocaine-mediated behaviours in mice by clinically relevant Ras-ERK inhibitors (2016) (33)
- Choice for Drug or Natural Reward Engages Largely Overlapping Neuronal Ensembles in the Infralimbic Prefrontal Cortex (2018) (33)
- Reduced sensitivity to sucrose in rats bred for helplessness: a study using the matching law (2005) (33)
- The impact of acetylcholinesterase inhibitors on the extracellular acetylcholine concentrations in the adult rat brain: A meta‐analysis (2012) (32)
- The influence of opioid antagonists on the discriminative stimulus effects of ethanol (1996) (32)
- Repeated Administration of the Neurotensin Receptor Antagonist SR 48692 Differentially Regulates Mesocortical and Mesolimbic Dopaminergic Systems (1998) (32)
- The use of a novel drinkometer system for assessing pharmacological treatment effects on ethanol consumption in rats. (2013) (32)
- Ethanol-induced alterations of amino acids measured by in vivo microdialysis in rats: a meta-analysis (2013) (32)
- The Need for Treatment Responsive Translational Biomarkers in Alcoholism Research. (2016) (31)
- The IMAGEN study: a decade of imaging genetics in adolescents (2020) (31)
- Voluntary alcohol intake in two rat lines selectively bred for learned helpless and non-helpless behavior (2005) (30)
- Animal models of craving: a roundtable discussion. (1999) (30)
- Incubation of Cocaine Seeking following Brief Cocaine Experience in Mice Is Enhanced by mGluR1 Blockade (2014) (30)
- Differential expression of presynaptic genes in a rat model of postnatal hypoxia: relevance to schizophrenia (2010) (30)
- Morphine‐Induced Locomotor and Neurochemical Stimulation is Enhanced in Transgenic Mice with Impaired Glucocorticoid Receptor Function (1996) (30)
- Global ethanol-induced enhancements of monoaminergic neurotransmission: a meta-analysis study. (2013) (30)
- Mesolimbic sites mediate the discriminative stimulus effects of morphine. (1994) (30)
- Appetitive odor-cue conditioning attenuates the acoustic startle response in rats (2008) (30)
- Role of the brain-gut axis in alcohol-related gastrointestinal diseases--what can we learn from new animal models? (2003) (30)
- Differential Roles for L-Type Calcium Channel Subtypes in Alcohol Dependence (2017) (29)
- Development of morphine-induced tolerance and withdrawal: Involvement of the clock gene mPer2 (2010) (29)
- Alcohol reinforcement and voluntary ethanol consumption. (2001) (29)
- Sensorimotor gating, working and social memory deficits in mice with reduced expression of the vesicular glutamate transporter VGLUT1 (2012) (29)
- Drugs for Relapse Prevention of Alcoholism (2005) (29)
- Ethanol and gene expression in brain. (2001) (29)
- Dopamine and opioid systems adaptation in alcoholism revisited: Convergent evidence from positron emission tomography and postmortem studies (2019) (29)
- Cannabinoids and the endocannabinoid system in reward processing and addiction: from mechanisms to interventions (2020) (28)
- Dnmt3a2 in the Nucleus Accumbens Shell Is Required for Reinstatement of Cocaine Seeking (2018) (28)
- Adolescent social rejection alters pain processing in a CB1 receptor dependent manner (2016) (28)
- Differences in the kappa opioid receptor mRNA content in distinct brain regions of two inbred mice strains (1998) (27)
- Role of Fyn tyrosine kinase in ethanol consumption by mice. (2003) (27)
- A Functional Tph2 C1473G Polymorphism Causes an Anxiety Phenotype via Compensatory Changes in the Serotonergic System (2012) (27)
- Time-dependent in-vivo effects of interleukin-2 on neurotransmitters in various cortices: Relationships with depressive-related and anxiety-like behaviour (2011) (27)
- Persistent strengthening of the prefrontal cortex – nucleus accumbens pathway during incubation of cocaine-seeking behavior (2017) (27)
- Chronic intermittent ethanol exposure in mice leads to an up-regulation of CRH/CRHR1 signaling. (2015) (26)
- Perinatal exposure to alcohol disturbs spatial learning and glutamate transmission‐related gene expression in the adult hippocampus (2011) (26)
- Modulation of morphine-induced sensitization by endogenous kappa opioid systems in the rat. (1993) (26)
- Metabolic shift of the kynurenine pathway impairs alcohol and cocaine seeking and relapse (2016) (26)
- Ventral tegmental area (VTA) injections of tyrosine hydroxylase phosphorothioate antisense oligonucleotide suppress operant behavior in rats (1994) (26)
- Differential involvement of the opioid receptor antagonist naloxone in motivational and hedonic aspects of reward (2010) (25)
- CREB activity in dopamine D1 receptor expressing neurons regulates cocaine-induced behavioral effects (2014) (25)
- Decreased Reward Sensitivity in Rats from the Fischer344 Strain Compared to Wistar Rats Is Paralleled by Differences in Endocannabinoid Signaling (2012) (25)
- Towards trans-diagnostic mechanisms in psychiatry: neurobehavioral profile of rats with a loss-of-function point mutation in the dopamine transporter gene (2017) (24)
- Negative Association Between MR‐Spectroscopic Glutamate Markers and Gray Matter Volume After Alcohol Withdrawal in the Hippocampus: A Translational Study in Humans and Rats (2017) (24)
- Expression of N-methyl-d-aspartate (NMDA) receptor subunits and splice variants in an animal model of long-term voluntary alcohol self-administration. (2008) (23)
- Structural synaptic elements are differentially regulated in superior temporal cortex of schizophrenia patients (2012) (23)
- Release and accumulation of neurotransmitters in the rat brain: acute effects of ethanol in vitro and effects of long-term voluntary ethanol intake. (1998) (23)
- Psilocybin and LSD have no long-lasting effects in an animal model of alcohol relapse (2020) (23)
- Efficacy and side effects of baclofen and the novel GABAB receptor positive allosteric modulator CMPPE in animal models for alcohol and cocaine addiction (2018) (23)
- Endogenous opioids and addiction (1995) (22)
- Central metabolite changes and activation of microglia after peripheral interleukin-2 challenge (2012) (22)
- Accurate quantification of the mRNA of NMDAR1 splice variants measured by competitive RT-PCR. (1999) (22)
- Strain‐specific responses of inbred mice to ethanol following food shortage (2004) (22)
- Melatonin reduces motivation for cocaine self-administration and prevents relapse-like behavior in rats (2017) (22)
- In silico pharmacology: drug design and discovery’s gate to the future (2013) (22)
- Publication trends in addiction research (2011) (22)
- Etomidate and propofol-hyposensitive GABAA receptor β3(N265M) mice show little changes in acute alcohol sensitivity but enhanced tolerance and withdrawal (2007) (22)
- Ethanol induces expression of the glutamate transporters EAAT1 and EAAT2 in organotypic cortical slice cultures. (2004) (21)
- Quantification of alcohol drinking patterns in mice (2015) (21)
- Dynorphin and κ-Opioid Receptor Dysregulation in the Dopaminergic Reward System of Human Alcoholics (2018) (21)
- Long‐lasting effect of NMDA receptor antagonist memantine on ethanol‐cue association and relapse (2015) (21)
- Neural Correlates of Failed Inhibitory Control as an Early Marker of Disordered Eating in Adolescents (2019) (21)
- Psilocybin targets a common molecular mechanism for cognitive impairment and increased craving in alcoholism (2021) (20)
- Adaptive dynamics of the 5‐HT systems following chronic administration of selective serotonin reuptake inhibitors: a meta‐analysis (2017) (20)
- Actions of Acamprosate on Neurons of the Central Nervous System (1996) (20)
- Autoradiographic distribution of μ-, δ- and κ1-opioid stimulated [35S]guanylyl-5′-O-(γ-thio)-triphosphate binding in human frontal cortex and cerebellum (2000) (20)
- Forced opiate withdrawal under anaesthesia augments and prolongs the occurrence of withdrawal signs in rats. (1998) (20)
- Is there a pharmacological basis for therapy with rapid opioid detoxification? (1999) (19)
- [One drink, one drunk--controlled drinking by alcoholics? 3-year-outcome after intensive outpatient treatment]. (2007) (19)
- Clock genes running amok (2007) (19)
- The ClockΔ19 mutation in mice fails to alter the primary and secondary reinforcing properties of nicotine. (2013) (19)
- Animal models of craving. (1999) (18)
- A methodological checklist for fMRI drug cue reactivity studies: development and expert consensus (2020) (18)
- Per1Brdm1 mice self-administer cocaine and reinstate cocaine-seeking behaviour following extinction (2011) (18)
- [The role of the glutamatergic system in alcohol addiction]. (2003) (18)
- Endocannabinoid LTD in Accumbal D1 Neurons Mediates Reward-Seeking Behavior (2020) (18)
- Effects of morphine withdrawal on μ-opioid receptor-stimulated guanylyl 5'-[γ-[35S]thio]-triphosphate autoradiography in rat brain (2002) (18)
- Gene expression in superior temporal cortex of schizophrenia patients (2014) (18)
- Adeno-associated virus (AAV)-mediated suppression of Ca2+/calmodulin kinase IV activity in the nucleus accumbens modulates emotional behaviour in mice (2007) (17)
- No basal or drug‐induced sex differences in striatal dopaminergic levels: a cluster and meta‐analysis of rat microdialysis studies (2019) (17)
- A translational systems biology approach in both animals and humans identifies a functionally related module of accumbal genes involved in the regulation of reward processing and binge drinking in males. (2016) (16)
- Involvement of mesolimbic κ-opioid systems in the discriminative stimulus effects of morphine (1994) (16)
- Low Smoking Exposure, the Adolescent Brain, and the Modulating Role of CHRNA5 Polymorphisms. (2019) (16)
- Aberrant choice behavior in alcoholism (2018) (16)
- In vivo structural imaging in rats reveals neuroanatomical correlates of behavioral sub‐dimensions of cocaine addiction (2018) (16)
- Interactive molecular networks obtained by computer-aided conversion of microarray data from brains of alcohol-drinking rats. (2009) (15)
- Time-dependent effects of striatal interleukin-2 on open field behaviour in rats (2009) (15)
- ERRATUM: The clock gene Per2 influences the glutamatergic system and modulates alcohol consumption (2005) (15)
- A gene-by-sex interaction for nicotine reward: evidence from humanized mice and epidemiology (2016) (15)
- The use of transgenic mice to study addictive behavior (2003) (15)
- Convergent functional genomics in addiction research - a translational approach to study candidate genes and gene networks (2013) (14)
- Modulation of the mesolimbic dopaminergic system by beta-endorphin-(1-27) as assessed by microdialysis. (1991) (14)
- The enhanced excitability of central neurons following chronic alcohol intake is reduced by Acamprosate (1995) (14)
- Association of plasma calcium concentrations with alcohol craving: New data on potential pathways (2017) (14)
- Basal activity level in mice predicts the initial and sensitized locomotor response to nicotine only in high responders (2014) (14)
- Deletion of Go2α abolishes cocaine‐induced behavioral sensitization by disturbing the striatal dopamine system (2008) (14)
- [18F]-Fluorodeoxyglucose-Positron Emission Tomography in Rats with Prolonged Cocaine Self-Administration Suggests Potential Brain Biomarkers for Addictive Behavior (2017) (14)
- No association of alcohol dependence with a NMDA-receptor 2B gene variant (2003) (14)
- Augmented stress-induced alcohol drinking and withdrawal in mice lacking functional natriuretic peptide-A receptors. (2010) (13)
- No changes in the oxytocin system in alcohol‐dependent female rodents and humans: Towards a sex‐specific psychopharmacology in alcoholism (2020) (13)
- Paradoxical augmented relapse in alcohol-dependent rats during deep-brain stimulation in the nucleus accumbens (2016) (13)
- XRCC5 as a Risk Gene for Alcohol Dependence: Evidence from a Genome-Wide Gene-Set-Based Analysis and Follow-up Studies in Drosophila and Humans (2015) (13)
- Challenges to medications development in treating alcohol dependence: an international perspective. (2004) (12)
- A phenotype-driven ENU mutagenesis screen for the identification of dominant mutations involved in alcohol consumption (2008) (12)
- mPer1 promotes morphine-induced locomotor sensitization and conditioned place preference via histone deacetylase activity (2017) (12)
- Behavioral neurobiology of alcohol addiction. Preface. (2013) (12)
- Approved cannabinoids for medical purposes – Comparative systematic review and meta-analysis for sleep and appetite (2021) (12)
- Dynamical state transitions into addictive behaviour and their early-warning signals (2017) (12)
- Targeted overexpression of CRH receptor subtype 1 in central amygdala neurons: effect on alcohol-seeking behavior (2018) (12)
- The effect of acamprosate on the development of morphineinduced behavioral sensitization in rats (2003) (12)
- Drinking Levels and Profiles of Alcohol Addicted Rats Predict Response to Nalmefene (2019) (12)
- Transcriptional regulation of L-type calcium channel subtypes Cav1.2 and Cav1.3 by nicotine and their potential role in nicotine sensitization. (2014) (12)
- Coordinated Prefrontal State Transition Leads Extinction of Reward-Seeking Behaviors (2020) (12)
- How to measure relapse in animals (2005) (12)
- Sign- and goal-tracking score does not correlate with addiction-like behavior following prolonged cocaine self-administration (2021) (11)
- Systemic neurotransmitter responses to clinically approved and experimental neuropsychiatric drugs (2018) (11)
- Targeting Glycine Reuptake in Alcohol Seeking and Relapse (2018) (11)
- Acute alcohol withdrawal and recovery in men lead to profound changes in DNA methylation profiles - a longitudinal clinical study. (2020) (11)
- Acamprosate: preclinical data (2005) (11)
- Infusions of Tyrosine Hydroxylase Antisense Oligodeoxynucleotide into Substantia Nigra of the Rat: Effects on Tyrosine Hydroxylase mRNA and Protein Content, Striatal Dopamine Release and Behaviour (1997) (11)
- Dissociable Role of Corticotropin Releasing Hormone Receptor Subtype 1 on Dopaminergic and D1 Dopaminoceptive Neurons in Cocaine Seeking Behavior (2017) (11)
- Sex differences in dopamine binding and modafinil conditioned place preference in mice. (2015) (11)
- The Calpain Inhibitor A-705253 Attenuates Alcohol-Seeking and Relapse with Low Side-Effect Profile (2016) (11)
- Perinatal exposure to alcohol reduces the expression of complexins I and II. (2009) (11)
- Enhanced extinction of contextual fear conditioning in ClockΔ19 mutant mice. (2014) (10)
- Anti-craving compounds: new pharmacological tools to study addictive processes (1997) (10)
- Autoradiographic distribution of mu-, delta- and kappa 1-opioid stimulated [35S]guanylyl-5'-O-(gamma-thio)-triphosphate binding in human frontal cortex and cerebellum. (2000) (10)
- Genetic Contribution to Alcohol Dependence: Investigation of a Heterogeneous German Sample of Individuals with Alcohol Dependence, Chronic Alcoholic Pancreatitis, and Alcohol-Related Cirrhosis (2017) (10)
- Measuring alcohol consumption in man--it is time for a change. (2006) (10)
- The Inhibition of RasGRF2, But Not RasGRF1, Alters Cocaine Reward in Mice (2019) (9)
- Pavlovian to Instrumental Transfer Responses Do Not Correlate With Addiction-Like Behavior in Rats (2019) (9)
- Baseline severity and the prediction of placebo response in clinical trials for alcohol dependence: A meta‐regression analysis to develop an enrichment strategy (2021) (9)
- Changes in cerebral [18F]-FDG uptake induced by acute alcohol administration in a rat model of alcoholism (2017) (9)
- Differential predictors for alcohol use in adolescents as a function of familial risk (2021) (8)
- Treating alcohol dependence with an abuse and misuse deterrent formulation of sodium oxybate: Results of a randomised, double-blind, placebo-controlled study (2021) (8)
- Medical cannabinoids: a pharmacology-based systematic review and meta-analysis for all relevant medical indications (2022) (8)
- Reduced sensitivity to ethanol and excessive drinking in a mouse model of neuropathic pain (2019) (8)
- Corrigendum: CREB activity in dopamine D1 receptor expressing neurons regulates cocaine-induced behavioral effects (2014) (7)
- Are Metabotropic Glutamate Receptors Promising Targets for the Treatment of Alcoholism? (2010) (7)
- Involvement of mesolimbic kappa-opioid systems in the discriminative stimulus effects of morphine. (1994) (7)
- Altered neural oscillations and elevated dopamine levels in the reward pathway during alcohol relapse (2017) (7)
- Reply to: Does acamprosate really produce its anti-relapse effects via calcium? No support from the PREDICT study in human alcoholics (2016) (7)
- Epigenome-wide association study of alcohol use disorder in five brain regions (2021) (7)
- A two-injection protocol for nicotine sensitization (2014) (7)
- Discriminative Stimulus Effects of Glutamate Release Inhibitors in Rats Trained to Discriminate Ethanol (1998) (6)
- Glutamate concentration in the anterior cingulate cortex in alcohol dependence: association with alcohol withdrawal and exploration of contribution from glutamatergic candidate genes (2018) (6)
- [Acamprosate--new preclinical research aspects]. (2003) (6)
- BEHAVIOURAL AND PHARMACOLOGICAL CHARACTERISTICS OF LONG‐TERM ALCOHOL SELF‐ADMINISTRATION (1998) (6)
- Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption (Proceedings of the National Academy Sciences of the United States of America (2011) 108, 17, (7119-7124)) (2011) (6)
- Amphetamine regulates NR2B expression in Go2α knockout mice and thereby sustains behavioral sensitization (2010) (6)
- Impulsivity is a heritable trait in rodents and associated with a novel quantitative trait locus on chromosome 1 (2020) (6)
- Female mice are more prone to develop an addictive-like phenotype for sugar consumption (2020) (6)
- Single-dose ethanol intoxication causes acute and lasting neuronal changes in the brain (2020) (6)
- Ethanol induces GAD67 and VGAT in slice cultures of newborn rat cerebral cortex (2005) (6)
- Effects of morphine withdrawal on micro-opioid receptor-stimulated guanylyl 5'-[gamma-[35S]thio]-triphosphate autoradiography in rat brain. (2002) (6)
- A call for systems approaches in addiction research. (2010) (6)
- [Opiate addiction. Pharmacologic and biochemical aspects]. (1992) (6)
- Glutamatergic compounds: a perspective (2005) (5)
- Disruption of reconsolidation processes is a balancing act - can it really account for change in psychotherapy? (2015) (5)
- Alcohol dependence is associated with a NMDA-receptor 2B gene variant (2001) (5)
- [Glutamate receptor agonists and alcohol dependence. Preclinical findings]. (1999) (5)
- Adverse social experiences in adolescent rats result in persistent sex-dependent effects on alcohol-seeking behavior. (2021) (5)
- Cocaine addicted rats show reduced neural activity as revealed by manganese-enhanced MRI (2020) (4)
- c‐Fos marking of identified midbrain neurons coactive after nicotine administration in‐vivo (2018) (4)
- Endorphins, pain relief and euphoria (1995) (4)
- The Rise of Three Rs Centres and Platforms in Europe* (2022) (4)
- Spatiotemporal Role of Transforming Growth Factor Beta 2 in Developing and Mature Mouse Hindbrain Serotonergic Neurons (2019) (4)
- Ten Points to Improve Reproducibility and Translation of Animal Research (2022) (4)
- The effects of xenon and nitrous oxide gases on alcohol relapse. (2014) (4)
- Editorial: Neurobehavioural Mechanisms of Resilience and Vulnerability in Addictive Disorders (2021) (4)
- Alcohol solution strength preference predicts compulsive-like drinking behaviour in rats. (2022) (3)
- Chronic alcohol intake regulates expression of SARS-CoV2 infection-relevant genes in an organ-specific manner (2022) (3)
- Building Bridges through Science (2017) (3)
- Multi-omics signatures of alcohol use disorder in the dorsal and ventral striatum (2021) (3)
- [The medical treatment of attention deficit hyperactivity disorder (ADHD) with amphetamines in children and adolescents]. (2012) (3)
- SEARCHING FOR THE ACAMPROSATE AND NALTREXONE RESPONDERS: PROJECT PREDICT.** (2004) (3)
- Transcriptional changes in insulin‐ and lipid metabolism‐related genes in the hippocampus of olfactory bulbectomized mice (2008) (3)
- Correction for Schumann et al., Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption (2011) (3)
- Controversial Research Areas (2000) (2)
- Effects of d-cycloserine on extinction of mesolimbic cue reactivity in alcoholism: a randomized placebo-controlled trial (2015) (2)
- Future perspectives on relapse prevention (2005) (2)
- Neurobiology of Addiction (2007) (2)
- ACAMPROSATE, BUT NOT NERAMEXANE, REDUCES CUE-INDUCED REINSTATEMENT OF ETHANOL-SEEKING BEHAVIOR. (2004) (2)
- [For and against: controlled drinking as useful and necessary treatment alternative]. (2005) (2)
- The alcohol deprivation effect model for studying relapse behaviour (2016) (2)
- Behavioral and Molecular Aspects of Alcohol Craving and Relapse (2003) (2)
- Epigenetic Signatures of Smoking in Five Brain Regions (2022) (2)
- Differential gene expression in the alcohol target organs liver and pancreas of wistar rats using DNA chip technology (2003) (2)
- NMDA RECEPTOR IN ALCOHOL RELAPSE. (2004) (2)
- Erratum to “Time-dependent in-vivo effects of interleukin-2 on neurotransmitters in various cortices: Relationships with depressive-related and anxiety-like behavior” [J. Neuroimmunol. 237(2011)23–32] (2011) (2)
- 37. Interleukin-2 affects social interaction behavior in relation to anxiety-like trait behavior in the elevated plus-maze in adult Wistar rats (2009) (2)
- The hypothalamus-pituitary-adrenocortical system: A biological substrate of vulnerability to drug addiction. (1999) (2)
- 1H MRS profiling at 9.4T in prefrontal cortex and hippocampus of ethanol dependent rats during intoxication, withdrawal and protracted abstinence (2010) (2)
- Quantum modeling of common sense. (2013) (2)
- Animal Models of Behavior: Alcohol Addiction (2010) (2)
- Calcium Carbonate Attenuates Withdrawal and Reduces Craving: A Randomized Controlled Trial in Alcohol-Dependent Patients (2021) (2)
- Alcohol reduces muscle fatigue through atomistic interactions with nicotinic receptors (2018) (2)
- Alcohol reduces muscle fatigue through atomistic interactions with nicotinic receptors (2018) (1)
- Why do we take drugs? From the drug-reinforcement theory to a novel concept of drug instrumentalization (2011) (1)
- Non-Specific Effects of Centrally Administered Oligonucleotides (1998) (1)
- P-67LOSING CONTROL: EXCESSIVE ALCOHOL SEEKING AFTER SELECTIVE INACTIVATION OF CUE-RESPONSIVE NEURONS IN THE INFRALIMBIC CORTEX (2015) (1)
- Acute and long-term sex-dependent effects of social instability stress on anxiety-like and social behaviours in Wistar rats (2022) (1)
- Plasma calcium concentration during detoxification predicts neural cue-reactivity and craving during early abstinence in alcohol-dependent patients (2021) (1)
- Post-mortem gene expression of calcium channels Cav1.2 and Cav1.3 in schizophrenia (2022) (1)
- Neuropharmacology of alcohol addiction. Commentary (2008) (1)
- Systemic neurotransmitter responses to clinically approved and experimental neuropsychiatric drugs (2018) (1)
- Sodium oxybate for the maintenance of abstinence in alcohol-dependent patients: An international, multicenter, randomized, double-blind, placebo-controlled trial (2022) (1)
- The Cannabinoid Receptor 1 as a Key Mediator of Adolescent Behavior (2017) (1)
- Better data, better policy and better lives: a call for improved drug monitoring and concerted responses. (2019) (1)
- Balance of Go1α and Go2α expression regulates motor function via the striatal dopaminergic system (2018) (1)
- SY09-2THE CALPAIN INHIBITOR A-705253 ATTENUATES ALCOHOL-SEEKING AND RELAPSE WITH LOW SIDE-EFFECT PROFILE (2015) (1)
- INCREASED SENSITIVITY TO AND SELF‐ADMINISTRATION OF MORPHINE IN TRANSGENIC MICE WITH IMPAIRED GLUCOCORTICOID RECEPTOR FUNCTION (1998) (1)
- How to Test Antisense Oligonucleotides in Animals (1999) (1)
- INTERACTION OF ETHANOL AND CLOCK GENES. (2004) (1)
- mGlu2 mechanism-based interventions to treat alcohol relapse (2022) (1)
- ETHANOL SELF-ADMINISTRATION AND REINSTATEMENT BEHAVIOUR IN mPER1 KNOCKOUT MICE. (2004) (1)
- Ethanol-induced alterations of amino acids measured by in vivo microdialysis in rats: a meta-analysis (2013) (1)
- Mechanism of Action of Acamprosate Focusingon the Glutamatergic System (2002) (1)
- EDITORIAL: Science meets public (2006) (1)
- Alcohol: Neurobiology of Alcohol Addiction (2016) (1)
- Neurobiology of Alcohol Addiction (2013) (1)
- In silico pharmacology: drug design and discovery’s gate to the future (2013) (1)
- The clock gene Period 2 influences the glutamatergic system and thereby modulates alcohol consumption (2005) (1)
- Impaired contextual fear conditioning in RasGRF2 mutant mice is likely Ras-ERK-dependent (2021) (1)
- NMDA Receptors in Accumbal D1 Neurons Influence Chronic Sugar Consumption and Relapse (2021) (1)
- S.28.02 Glycine transporter-1 blockade leads to persistently reduced relapse-like alcohol drinking in rats (2011) (1)
- Disrupted circadian expression of β‐arrestin 2 affects reward‐related µ‐opioid receptor function in alcohol dependence (2021) (1)
- Alterations of the Biological Clock May Contribute to the Emergence of Mental Disorders During Adolescence (2018) (1)
- Analysis of Rare Variants in the Alcohol Dependence Candidate Gene GATA4 (2016) (1)
- S.10.01 Animal models of relapse (1997) (1)
- S.35.03 Melatonin receptors as a target to treat alcohol addiction (2017) (1)
- NMDA RECEPTORS AND RELAPSE: BEHAVIOURAL AND GENETIC ANALYSIS. (2004) (1)
- P.2.004 Sugar-addictive phenotypes in mice (2018) (1)
- Impulsivity is a heritable trait in rodents and associated with a novel quantitative trait locus on chromosome 1 (2020) (0)
- S11-4OXYTOCIN SYSTEM AND ALCOHOL REWARD: FROM RODENTS TO MAN (2017) (0)
- NANOSYMPOSIUM N 4 NEUROLOGICAL DISORDERS: NEW INSIGHTS INTO PATHOPHYSIOLOGICAL SUBSTRATES AND TREATMENT-RELATED BEHAVIOURAL COMPLICATIONS CHAIRc FRANCK DURIF NS.4.1 - ACUTE AND LONG-TERM SOCIAL REJECTION DURING ADOLESCENCE ALTERS PAIN PERCEPTION IN FEMALE RATS (2013) (0)
- P.6.c.009 The role of ras guanine nucleotide-releasing factor 1 (ras-GRF1) in cocaine self-administration (2014) (0)
- A common molecular mechanism for cognitive deficits and craving in alcoholism (2020) (0)
- Cannabinoids and adolescent behaviour (2014) (0)
- Interleukin-2 reduces extracellular cortical serotonin: Impact on depressive-related and anxiety-like behaviour (2010) (0)
- Sodium Oxybate for Alcohol Dependence: A Network Meta-Regression Analysis Considering Population Severity at Baseline and Treatment Duration (2023) (0)
- S.07.04 Specific deletion of AMPA-R GluR1 subunits in D1 expressing neurons: cocaine-addiction related behavioural consequences (2009) (0)
- Comment on Flagel et al.: Sign-tracking as a predictor of addiction vulnerability (2021) (0)
- Long-term sensitization of rat spinal neurons induced by adolescent psychophysical stress is further enhanced by a mild-nociceptive lumbar input (2021) (0)
- Molecular mechanisms of ethanol-induced Deficits in Muscle Strength (2017) (0)
- Targeted overexpression of CRH receptor subtype 1 in central amygdala neurons: effect on alcohol-seeking behavior (2018) (0)
- NEW ALCOHOL ANTICRAVING COMPOUNDS (1999) (0)
- MICROARRAY-BASED GENE EXPRESSION PROFILING IN LONG-TERM ALCOHOL DRINKING AA-, P-, AND HAD-RATS. (2004) (0)
- PL3A SYSTEMS MEDICINE APPROACH TOWARDS UNDERSTANDING ALCOHOL ADDICTION (2015) (0)
- 104-3 Neurotensin antagonists and dopaminergic function (1997) (0)
- A study of oxytocin effects within the medial entorhinal cortex-hippocampus domain in rats (2021) (0)
- Advances in Drug Addiction (2016) (0)
- DNA methylation in cocaine use disorder–An epigenome-wide approach in the human prefrontal cortex (2022) (0)
- Association of NPY Receptor 2 Polymorphism with Alcohol Dependence (2013) (0)
- 260. Modulations of the HPA-system by mutagenesis in mice (1998) (0)
- S.14.02 Glutamatergic mechanisms in alcohol addiction (2010) (0)
- SY03-3OPIOIDERGIC MECHANISM IN ALCOHOLISM: TRANSLATIONAL STUDIES IN RODENTS AND HUMANS (2015) (0)
- Welcome to Berlin and the 27th ECNP congress (2014) (0)
- Elevated alcohol consumption in mice lacking functional natriruetic peptide-A receptor (2007) (0)
- EDITORIAL: Addiction Biology reaches new heights (2009) (0)
- Metabolic shift of the kynurenine pathway impairs alcohol and cocaine seeking and relapse (2016) (0)
- Correction to: Sign‑ and goal‑tracking score does not correlate with addiction‑like behavior following prolonged cocaine self‑administration (2021) (0)
- Persistent muscle hyperalgesia after adolescent stress is exacerbated by a mild-nociceptive input in adulthood and is associated with microglia activation (2022) (0)
- EFFECT OF ETHANOL ON EXPRESSION OF SERINE RACEMASE IN CULTURED RAT ASTROCYTES. (2004) (0)
- Chronic alcohol consumption and COVID-19 infection risk: A narrative review. (2023) (0)
- Efficacy and side effects of baclofen and the novel GABAB receptor positive allosteric modulator CMPPE in animal models for alcohol and cocaine addiction (2018) (0)
- P.4.04 Specific deletion of AMPA-R GluR1 subunits in D1 expressing neurons: cocaine-addiction related behavioural consequences (2009) (0)
- Neurochemical fingerprints of psychiatric drugs (2017) (0)
- Faculty of 1000 evaluation for The emperor's new wardrobe: Rebalancing diversity of animal models in neuroscience research. (2018) (0)
- Enhanced and Delayed Stress-induced Body Weight in Mice Lacking Functional Natriuretic Peptide-a Receptors (2009) (0)
- 19. Interleukin-2 reduces extracellular cortical serotonin and increases depression-related behaviour in the forced swim test in rats (2009) (0)
- An integrated approach to identify neurobiological mechanisms of addictive behaviour (2006) (0)
- Gene-set based analysis for alcohol dependence (2013) (0)
- Glutamatergic targets for new alcohol medications (2013) (0)
- Contents page + Editorial Board + Cover figure legend (2014) (0)
- Faculty Opinions recommendation of Sub-dimensions of Alcohol Use Disorder in Alcohol Preferring and Non-preferring Rats, a Comparative Study. (2019) (0)
- Convergent functional genomics in addiction research - a translational approach to study candidate genes and gene networks (2013) (0)
- Drug-induced behaviors in transgenic mice with ablation of the NR1 subunit of the NMDA receptor in neurons expressing the dopamine D1 receptors (2009) (0)
- M93 SYSMEDSUDS NETWORK - COMPARATIVE AND INTEGRATIVE COMPUTATIONAL ANALYSIS OF COMMON AND SPECIFIC MULTI-OMICS PROFILES FOR VARIOUS SUDS (2019) (0)
- μ-opioid system in alcohol dependence: Carfentanil-PET, risk of relapse and synopsis with post mortem data. (2015) (0)
- CROSS-TALK OF CORTICOTROPIN RELEASING HORMONE RECEPTOR SUBTYPE 1 WITH DOPAMINE D1 RECEPTOR: FUNCTIONAL RELEVANCE IN ALCOHOL DEPENDENCE (2015) (0)
- BINGE ETHANOL VAPOUR EXPOSURE AND ITS EFFECTS ON ANTIOXIDANT DEFENSE MECHANISMS IN THE LIVER AND PANCREAS OF RATS. (2004) (0)
- Neurochemical aspects of opioid addiction (1990) (0)
- Glutamatergic Brain Systems and Addiction (1996) (0)
- EUROPEAN SOCIETY FOR BIOMEDICAL RESEARCH ON ALCOHOLISM 12 – 15 SEPTEMBER 2015 VALENCIA , SPAIN (2015) (0)
- New regulations for animal research – a chance to shine for in silico approaches (2015) (0)
- Planning preclinical confirmatory multicenter trials to strengthen translation from basic to clinical research – a multi-stakeholder workshop report (2022) (0)
- W43. DNA METHYLATION-BASED ASSESSMENT OF SMOKING STATUS IN THE BRAIN (2021) (0)
- Neurobiology of Alcohol Use Disorder (2014) (0)
- Adverse Social Experiences in Adolescent Rats Results in Persisting Sex-Dependent Effects on Alcohol-Seeking Behavior (2020) (0)
- Generalized habitual tendencies in alcohol dependent rats (2022) (0)
- Systemic interleukin-2 affects individual anxiety-related social behaviour, gene-transcription and metabolites in the brain (2010) (0)
- P.2.019 The role of Ras guanine nucleotide-releasing factor 1 in cocaine self-administration (2014) (0)
- Dynorphin and κ-Opioid Receptor Dysregulation in the Dopaminergic Reward System of Human Alcoholics (2018) (0)
- Circadian rhythm gene Period1 mediates stress-induced alcohol drinking behaviour (2008) (0)
- How to measure addictive behaviour in animal experiments (2000) (0)
- To Open Up New Vistas in Basic and Preclinical Addiction Research (2010) (0)
- EFFICACY OF ADDITIONAL PSYCHOTHERAPY FOR THE ROLE OF DOPAMINE D3 RECEPTORS IN ALCOHOL CRAVING AND RELAPSE. (2004) (0)
- Perinatal exposure to alcohol disturbs spatial learning and glutamatergic neurotransmission in the hippocampus (2011) (0)
- Alcoholism: the molecular basis of addiction and deprivation (2020) (0)
- ALCOHOL DRINKING AND WITHDRAWAL IN MICE LACKING A FUNCTIONAL CRH RECEPTOR 1 (1998) (0)
- C-FOS MAPPING AND GENE EXPRESSION PROFILES IN RATS UNDERGOING ALCOHOL DEPRIVATION EFFECT. (2004) (0)
- Neurobehavioural effects of ethanol in GluR-A and GluR-C knockout mice (2003) (0)
- P.6.b.002 Compulsive-impulsive alcohol consumption in serotonin deficient vesicular monoamine transporter 2 (Vmat2) knockout mice (2012) (0)
- Faculty Opinions recommendation of NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses. (2012) (0)
- mPer1 promotes morphine-induced locomotor sensitization and conditioned place preference via histone deacetylase activity (2017) (0)
- Involvement of opioids in dopaminergic systems (1996) (0)
- Investigating the Molecular Mechanisms of Alcohol Use Disorder in Postmortem Human Brain Tissue (2023) (0)
- Drug craving in animals (1998) (0)
- Inhibition of proteasome function in rat nigrostriatal dopaminergic neurons as an animal model of Parkinson ’ s disease for studying neuroprotective compounds (2010) (0)
- The clock gene PER1 and alcohol: A stress-related gene X environment interaction (2008) (0)
- P.2.008 The role of glutamatergic receptors within the dopaminergic reinforcement system in alcohol-dependent phenotypes (2014) (0)
- Disrupting Reconsolidation of Alcohol Memories Reduces Cue-induced Alcohol Seeking Behavior in Rats (2009) (0)
- P.6.a.007 The role of glutamatergic receptors within the dopaminergic reinforcement system in alcohol-dependent phenotypes (2014) (0)
- S.11.04 Key role of loss of corticostriatal mGluR2 in the pathophysiology of alcoholism (2016) (0)
- A Systematic Review and Meta-analysis on the Transcriptomic Signatures in Alcohol Use Disorder – a Translational Approach (2022) (0)
- AMYGDALA DOPAMINE D1 AND CORTICOTROPIN RELEASING HORMONE RECEPTOR 1 INTERACTIONS IN ALCOHOL DEPENDENCE (2014) (0)
- 101. DNA Methylation in Cocaine Use Disorder – An Epigenome-Wide Approach in the Human Prefrontal Cortex (2023) (0)
- PL.01.01 New targets for the treatment of addiction (2014) (0)
- Early warning signals for dynamical phase transitions into addictive behavior (2016) (0)
- GLUR-C KNOCKOUT MICE DO NOT EXHIBIT AN ALCOHOL DEPRIVATION EFFECT AND SHOW LESS ALCOHOL SEEKING BEHAVIOUR. (2004) (0)
- Author response: Impairment of cocaine-mediated behaviours in mice by clinically relevant Ras-ERK inhibitors (2016) (0)
- SA63METHYLATION PROFILES DURING ACUTE ALCOHOL WITHDRAWAL IN A CLINICAL SAMPLE (2019) (0)
- P.6.a.016 Losing control: excessive alcohol seeking after selective inactivation of cue-responsive neurons in the infralimbic cortex (2014) (0)
- Incentive learning underlying cocaine relapse requires mGluR 5 receptors located on dopamine D 1 receptor expressing neurons (2019) (0)
- Melatonin receptors as a target to treat alcohol addiction (2017) (0)
- The κ-opioid receptor antagonist nor-binaltorphimine (nor-BNI) facilitates the development of morphine-induced behavioral sensitization (1995) (0)
- P0211 - Increased alcohol sensitivity to stress in mice lacking a functional natriuretic peptide-A receptor (2008) (0)
- Past and current opinions : what is the role of dopamine within the mesolimbic system ? (0)
- Methods for Behavioural Assessment of Drug-Reinforcement and Addictive Features (2006) (0)
- Progesterone/Estradiol Ratio Is Related to Real-Life Alcohol Consumption in Alcohol Use Disorder in a Sex- and Menstrual Cycle Phase-Dependent Manner (2022) (0)
- VOLANTARY ETHONAL CONSUMTION AND STRESS-INDUCED DRINKING IN ORL-1 KNOCKOUT MICE. (2004) (0)
- Polygenic risk scores for nicotine use and family history of smoking are associated with smoking behaviour (2022) (0)
- EFFFECTS OF INTRA-ACCUMBENS INJECTIONS OF DAMGO, DPDPE AND NALOXONE ON ETHANOL SELF-ADMINISTRATION (1996) (0)
- Extracellular cortical serotonin and depression-related behavior in the forced swim test is influenced by interleukin-2 (2009) (0)
- Changes in glutamate-catecholamine interactions underlie persistence of drug-conditioned behaviors (2010) (0)
- Pharmacological Disruption of Alcohol-related Memories - Therapeutic Impact of the Theory of Memory Reconsolidation (2009) (0)
- Stress-induced alcohol drinking and withdrawal in mice lacking functional natriruetic peptide-A receptors (2009) (0)
- Melatonin reduces motivation for cocaine self-administration and prevents relapse-like behavior in rats (2017) (0)
- Translational FDG-PET studies in alcohol and cocaine addicted rats (2017) (0)
- The Current Status and Work of Three Rs Centres and Platforms in Europe* (2022) (0)
- Abstracts Second Congress of the European Society for Clinical Neuropharmacology (1995) (0)
- GENETIC ANALYSIS OF CIRCADIAN RHYTHM GENES PER1 AND PER2 IN PATIENTS WITH ALCOHOL DEPENDENCE. (2004) (0)
- New regulations for animal research – a chance to shine for in silico approaches (2015) (0)
- Nicotine self-administration and ERK signaling are altered in RasGRF2 knockout mice (2022) (0)
- Sex and age specific effects on the development of addiction and compulsive-like drinking in rats (2022) (0)
- SAT1-2THE ROLE OF THE OPIOID SYSTEMS IN THE BRAINS MOTIVATIONAL SYSTEM (2015) (0)
- ERR and dPECR Suggest a Link Between Neuroprotection and the Regulation of Ethanol Consumption Preference (2021) (0)
- Neurobiology of Alcohol (2021) (0)
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What Schools Are Affiliated With Rainer Spanagel?
Rainer Spanagel is affiliated with the following schools:
