Rakesh Jain
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American cancer researcher
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Rakesh Jain's Degrees
- Bachelors Biology University of California, Berkeley
- PhD Molecular Biology Stanford University
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Why Is Rakesh Jain Influential?
(Suggest an Edit or Addition)According to Wikipedia, Rakesh K. Jain is the Andrew Werk Cook Professor of Tumor Biology at Massachusetts General Hospital in the Harvard Medical School and director of the E.L. Steele Laboratories for Tumor Biology at the Massachusetts General Hospital.
Rakesh Jain's Published Works
Published Works
- Angiogenesis in cancer and other diseases (2000) (8678)
- Normalization of Tumor Vasculature: An Emerging Concept in Antiangiogenic Therapy (2005) (5031)
- Molecular mechanisms and clinical applications of angiogenesis (2011) (4433)
- Photodynamic therapy for cancer (2003) (4291)
- Understanding the tumor immune microenvironment (TIME) for effective therapy (2018) (2583)
- Delivering nanomedicine to solid tumors (2010) (2571)
- Molecular regulation of vessel maturation (2003) (2474)
- Regulation of transport pathways in tumor vessels: role of tumor type and microenvironment. (1998) (2248)
- Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis (1998) (2183)
- Normalizing tumor vasculature with anti-angiogenic therapy: A new paradigm for combination therapy (2001) (2070)
- Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer (2004) (1997)
- AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients. (2007) (1754)
- Vascular permeability in a human tumor xenograft: molecular size dependence and cutoff size. (1995) (1719)
- Interstitial pH and pO2 gradients in solid tumors in vivo: High-resolution measurements reveal a lack of correlation (1997) (1602)
- Openings between defective endothelial cells explain tumor vessel leakiness. (2000) (1567)
- Determinants of tumor blood flow: a review. (1988) (1475)
- Transport of molecules in the tumor interstitium: a review. (1987) (1426)
- Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases (2011) (1385)
- A framework for advancing our understanding of cancer-associated fibroblasts (2020) (1376)
- Normalization of the vasculature for treatment of cancer and other diseases. (2011) (1307)
- Angiogenesis in brain tumours (2007) (1303)
- Hyperplasia of lymphatic vessels in VEGF-C transgenic mice. (1997) (1291)
- Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: role of oxygenation, angiopoietin-1, and matrix metalloproteinases. (2004) (1263)
- Challenges and key considerations of the enhanced permeability and retention effect for nanomedicine drug delivery in oncology. (2013) (1142)
- Vascular Normalization by Vascular Endothelial Growth Factor Receptor 2 Blockade Induces a Pressure Gradient Across the Vasculature and Improves Drug Penetration in Tumors (2004) (1136)
- Lessons from phase III clinical trials on anti-VEGF therapy for cancer (2006) (1078)
- Role of extracellular matrix assembly in interstitial transport in solid tumors. (2000) (1073)
- The role of nitric oxide in tumour progression (2006) (1069)
- Compact high-quality CdSe-CdS core-shell nanocrystals with narrow emission linewidths and suppressed blinking. (2013) (1057)
- Antiangiogenesis strategies revisited: from starving tumors to alleviating hypoxia. (2014) (1047)
- Tumor Induction of VEGF Promoter Activity in Stromal Cells (1998) (992)
- Abnormalities in pericytes on blood vessels and endothelial sprouts in tumors. (2002) (983)
- Predominant role of endothelial nitric oxide synthase in vascular endothelial growth factor-induced angiogenesis and vascular permeability (2001) (958)
- Microvascular permeability and interstitial penetration of sterically stabilized (stealth) liposomes in a human tumor xenograft. (1994) (954)
- Lymphatic Metastasis in the Absence of Functional Intratumor Lymphatics (2002) (946)
- Enhancing cancer immunotherapy using antiangiogenics: opportunities and challenges (2018) (926)
- Multistage nanoparticle delivery system for deep penetration into tumor tissue (2011) (894)
- Normalizing tumor microenvironment to treat cancer: bench to bedside to biomarkers. (2013) (880)
- Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner (2012) (873)
- Dynamic imaging of collagen and its modulation in tumors in vivo using second-harmonic generation (2003) (831)
- Transport of fluid and macromolecules in tumors. I. Role of interstitial pressure and convection. (1989) (823)
- Barriers to drug delivery in solid tumors. (1994) (788)
- Interstitial pressure gradients in tissue-isolated and subcutaneous tumors: implications for therapy. (1990) (771)
- Pathology: Cancer cells compress intratumour vessels (2004) (757)
- Vascular normalizing doses of antiangiogenic treatment reprogram the immunosuppressive tumor microenvironment and enhance immunotherapy (2012) (746)
- Solid stress inhibits the growth of multicellular tumor spheroids (1997) (738)
- Mechanisms of heterogeneous distribution of monoclonal antibodies and other macromolecules in tumors: significance of elevated interstitial pressure. (1988) (729)
- Engineering vascularized tissue (2005) (710)
- Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody. (1996) (703)
- Anti-Vascular endothelial growth factor treatment augments tumor radiation response under normoxic or hypoxic conditions. (2000) (696)
- Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels (2013) (692)
- Three-dimensional microscopy of the tumor microenvironment in vivo using optical frequency domain imaging (2009) (691)
- Tissue engineering: Creation of long-lasting blood vessels (2004) (680)
- Mosaic blood vessels in tumors: frequency of cancer cells in contact with flowing blood. (2000) (674)
- Tumour biology: Herceptin acts as an anti-angiogenic cocktail (2002) (673)
- Transport of molecules, particles, and cells in solid tumors. (1999) (668)
- Tumor microvasculature and microenvironment: targets for anti-angiogenesis and normalization. (2007) (661)
- Strategies for advancing cancer nanomedicine. (2013) (659)
- The role of mechanical forces in tumor growth and therapy. (2014) (653)
- Transport of molecules across tumor vasculature (2004) (649)
- The blood–brain barrier and blood–tumour barrier in brain tumours and metastases (2019) (618)
- Dissecting tumour pathophysiology using intravital microscopy (2002) (612)
- Delivery of novel therapeutic agents in tumors: physiological barriers and strategies. (1990) (595)
- Physiological barriers to delivery of monoclonal antibodies and other macromolecules in tumors. (1990) (591)
- Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors (2012) (588)
- Role of tumor–host interactions in interstitial diffusion of macromolecules: Cranial vs. subcutaneous tumors (2001) (580)
- Role of HIF-1 alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis (vol 394, pg 485, 1998) (1998) (579)
- Microvascular permeability of normal and neoplastic tissues. (1986) (576)
- Increased microvascular density and enhanced leukocyte rolling and adhesion in the skin of VEGF transgenic mice. (1998) (559)
- Physiologically based pharmacokinetic modeling: principles and applications. (1983) (558)
- Bone marrow-derived mesenchymal stem cells facilitate engineering of long-lasting functional vasculature. (2008) (555)
- Biomarkers of response and resistance to antiangiogenic therapy (2009) (554)
- Effect of vascular normalization by antiangiogenic therapy on interstitial hypertension, peritumor edema, and lymphatic metastasis: insights from a mathematical model. (2007) (552)
- Losartan inhibits collagen I synthesis and improves the distribution and efficacy of nanotherapeutics in tumors (2011) (550)
- Microvascular architecture in a mammary carcinoma: branching patterns and vessel dimensions. (1991) (541)
- Tumor microenvironment abnormalities: Causes, consequences, and strategies to normalize (2007) (532)
- Efficacy, safety, and biomarkers of neoadjuvant bevacizumab, radiation therapy, and fluorouracil in rectal cancer: a multidisciplinary phase II study. (2009) (519)
- Microvascular pressure is the principal driving force for interstitial hypertension in solid tumors: implications for vascular collapse. (1992) (512)
- Diffusion and convection in collagen gels: implications for transport in the tumor interstitium. (2002) (502)
- Phase II study of cediranib, an oral pan-vascular endothelial growth factor receptor tyrosine kinase inhibitor, in patients with recurrent glioblastoma. (2010) (494)
- Delivery of molecular and nanoscale medicine to tumors: transport barriers and strategies. (2011) (492)
- Malignant cells facilitate lung metastasis by bringing their own soil (2010) (489)
- Vascular normalization as an emerging strategy to enhance cancer immunotherapy. (2013) (485)
- Absence of functional lymphatics within a murine sarcoma: a molecular and functional evaluation. (2000) (481)
- Vascular permeability and microcirculation of gliomas and mammary carcinomas transplanted in rat and mouse cranial windows. (1994) (475)
- Diffusion of macromolecules in agarose gels: comparison of linear and globular configurations. (1999) (475)
- Delivery of molecular and cellular medicine to solid tumors. (2001) (471)
- Phase III randomized trial comparing the efficacy of cediranib as monotherapy, and in combination with lomustine, versus lomustine alone in patients with recurrent glioblastoma. (2013) (469)
- Efficacy, safety, and potential biomarkers of sunitinib monotherapy in advanced hepatocellular carcinoma: a phase II study. (2009) (459)
- Mechanical compression drives cancer cells toward invasive phenotype (2011) (457)
- HCC and angiogenesis: possible targets and future directions (2011) (455)
- Quantum dots spectrally distinguish multiple species within the tumor milieu in vivo (2005) (438)
- The biology of brain metastases—translation to new therapies (2011) (432)
- Surrogate markers for antiangiogenic therapy and dose-limiting toxicities for bevacizumab with radiation and chemotherapy: continued experience of a phase I trial in rectal cancer patients. (2005) (429)
- LYVE-1 is not restricted to the lymph vessels: expression in normal liver blood sinusoids and down-regulation in human liver cancer and cirrhosis. (2001) (425)
- Angiogenesis, microvascular architecture, microhemodynamics, and interstitial fluid pressure during early growth of human adenocarcinoma LS174T in SCID mice. (1992) (417)
- Hypoxia and acidosis independently up-regulate vascular endothelial growth factor transcription in brain tumors in vivo. (2001) (416)
- Next-generation in vivo optical imaging with short-wave infrared quantum dots (2017) (407)
- Fluorescent nanorods and nanospheres for real-time in vivo probing of nanoparticle shape-dependent tumor penetration. (2011) (403)
- The next frontier of molecular medicine: Delivery of therapeutics (1998) (401)
- Tumor Microvasculature and Microenvironment: Novel Insights Through Intravital Imaging in Pre‐Clinical Models (2010) (398)
- Micro-Environmental Mechanical Stress Controls Tumor Spheroid Size and Morphology by Suppressing Proliferation and Inducing Apoptosis in Cancer Cells (2009) (397)
- Quantitative angiogenesis assays: Progress and problems (1997) (397)
- In vivo measurement of gene expression, angiogenesis and physiological function in tumors using multiphoton laser scanning microscopy (2001) (394)
- Acid production in glycolysis-impaired tumors provides new insights into tumor metabolism. (2002) (394)
- Endothelial cell death, angiogenesis, and microvascular function after castration in an androgen-dependent tumor: role of vascular endothelial growth factor. (1998) (393)
- Shortwave infrared fluorescence imaging with the clinically approved near-infrared dye indocyanine green (2017) (389)
- CXCL12 (SDF1α)-CXCR4/CXCR7 Pathway Inhibition: An Emerging Sensitizer for Anticancer Therapies? (2011) (388)
- Direct measurement of interstitial convection and diffusion of albumin in normal and neoplastic tissues by fluorescence photobleaching. (1989) (377)
- Hearing improvement after bevacizumab in patients with neurofibromatosis type 2. (2009) (377)
- Transport of fluid and macromolecules in tumors. III. Role of binding and metabolism. (1991) (373)
- PF-06463922, an ALK/ROS1 Inhibitor, Overcomes Resistance to First and Second Generation ALK Inhibitors in Preclinical Models. (2015) (373)
- Consensus guidelines for the use and interpretation of angiogenesis assays (2018) (370)
- Vascular and interstitial barriers to delivery of therapeutic agents in tumors (1990) (369)
- A "vascular normalization index" as potential mechanistic biomarker to predict survival after a single dose of cediranib in recurrent glioblastoma patients. (2009) (362)
- Degradation of fibrillar collagen in a human melanoma xenograft improves the efficacy of an oncolytic herpes simplex virus vector. (2006) (359)
- The candidate tumour suppressor protein ING4 regulates brain tumour growth and angiogenesis (2004) (359)
- Augmentation of transvascular transport of macromolecules and nanoparticles in tumors using vascular endothelial growth factor. (1999) (358)
- Cationic charge determines the distribution of liposomes between the vascular and extravascular compartments of tumors. (2002) (357)
- Paracrine Regulation of Angiogenesis and Adipocyte Differentiation During In Vivo Adipogenesis (2003) (356)
- Fractals and cancer. (2000) (354)
- Platelets and platelet adhesion support angiogenesis while preventing excessive hemorrhage. (2006) (348)
- Taxane-induced apoptosis decompresses blood vessels and lowers interstitial fluid pressure in solid tumors: clinical implications. (1999) (346)
- Transport of fluid and macromolecules in tumors. II. Role of heterogeneous perfusion and lymphatics. (1990) (342)
- Delivery of molecular and cellular medicine to solid tumors. (1997) (339)
- Imaging steps of lymphatic metastasis reveals that vascular endothelial growth factor-C increases metastasis by increasing delivery of cancer cells to lymph nodes: therapeutic implications. (2006) (337)
- Combining two strategies to improve perfusion and drug delivery in solid tumors (2013) (335)
- Differential in vivo potential of endothelial progenitor cells from human umbilical cord blood and adult peripheral blood to form functional long-lasting vessels. (2008) (335)
- Differential response of normal and tumor microcirculation to hyperthermia. (1984) (334)
- A nanoparticle size series for in vivo fluorescence imaging. (2010) (327)
- CXCR4 inhibition in tumor microenvironment facilitates anti‐programmed death receptor‐1 immunotherapy in sorafenib‐treated hepatocellular carcinoma in mice (2015) (327)
- Diffusion of particles in the extracellular matrix: the effect of repulsive electrostatic interactions. (2010) (325)
- Delivery of Molecular Medicine to Solid Tumors (1996) (320)
- Noninvasive measurement of interstitial pH profiles in normal and neoplastic tissue using fluorescence ratio imaging microscopy. (1994) (319)
- Origins of lymphatic and distant metastases in human colorectal cancer (2017) (319)
- Chemotherapy elicits pro-metastatic extracellular vesicles in breast cancer models (2018) (316)
- Improved tumor oxygenation and survival in glioblastoma patients who show increased blood perfusion after cediranib and chemoradiation (2013) (314)
- Vascular endothelial growth factor receptor-2-blocking antibody potentiates radiation-induced long-term control of human tumor xenografts. (2001) (309)
- Endothelial cells derived from human embryonic stem cells form durable blood vessels in vivo (2007) (304)
- Edema control by cediranib, a vascular endothelial growth factor receptor-targeted kinase inhibitor, prolongs survival despite persistent brain tumor growth in mice. (2009) (303)
- Coevolution of solid stress and interstitial fluid pressure in tumors during progression: implications for vascular collapse. (2013) (302)
- Tumor angiogenesis and accessibility: role of vascular endothelial growth factor. (2002) (299)
- Oncotic pressure in solid tumors is elevated. (2000) (298)
- During angiogenesis, vascular endothelial growth factor and basic fibroblast growth factor regulate natural killer cell adhesion to tumor endothelium. (1996) (297)
- Extravascular diffusion in normal and neoplastic tissues. (1984) (297)
- Delivery of molecular medicine to solid tumors: lessons from in vivo imaging of gene expression and function. (2001) (295)
- Reengineering the Physical Microenvironment of Tumors to Improve Drug Delivery and Efficacy: From Mathematical Modeling to Bench to Bedside. (2018) (292)
- Hindered diffusion in agarose gels: test of effective medium model. (1996) (291)
- Vascular normalization as a therapeutic strategy for malignant and nonmalignant disease. (2012) (283)
- Total Neoadjuvant Therapy With FOLFIRINOX in Combination With Losartan Followed by Chemoradiotherapy for Locally Advanced Pancreatic Cancer: A Phase 2 Clinical Trial. (2019) (283)
- In vivo measurement of gene expression, angiogenesis and physiological function in tumors using multiphoton laser scanning microscopy (2001) (282)
- A protocol for phenotypic detection and enumeration of circulating endothelial cells and circulating progenitor cells in human blood (2007) (280)
- Solid stress generated by spheroid growth estimated using a linear poroelasticity model. (2003) (280)
- BIM expression in treatment-naive cancers predicts responsiveness to kinase inhibitors. (2011) (276)
- Time-dependent behavior of interstitial fluid pressure in solid tumors: implications for drug delivery. (1995) (270)
- Intussusceptive microvascular growth in a human colon adenocarcinoma xenograft: a novel mechanism of tumor angiogenesis. (1996) (269)
- Obesity-Induced Inflammation and Desmoplasia Promote Pancreatic Cancer Progression and Resistance to Chemotherapy. (2016) (269)
- Vascular endothelial growth factor (VEGF) modulation by targeting hypoxia-inducible factor-1alpha--> hypoxia response element--> VEGF cascade differentially regulates vascular response and growth rate in tumors. (2000) (269)
- TGF-β blockade improves the distribution and efficacy of therapeutics in breast carcinoma by normalizing the tumor stroma (2012) (268)
- Acidic Extracellular pH Induces Vascular Endothelial Growth Factor (VEGF) in Human Glioblastoma Cells via ERK1/2 MAPK Signaling Pathway (2002) (266)
- Antiangiogenic therapy for cancer: current and emerging concepts. (2005) (265)
- Recruitment of myeloid but not endothelial precursor cells facilitates tumor regrowth after local irradiation. (2010) (264)
- Improving cancer immunotherapy using nanomedicines: progress, opportunities and challenges (2020) (264)
- Ang-2/VEGF bispecific antibody reprograms macrophages and resident microglia to anti-tumor phenotype and prolongs glioblastoma survival (2016) (263)
- Compact biocompatible quantum dots via RAFT-mediated synthesis of imidazole-based random copolymer ligand. (2009) (262)
- Role of tumor vascular architecture in nutrient and drug delivery: an invasion percolation-based network model. (1996) (261)
- Interstitial hypertension in human breast and colorectal tumors. (1992) (259)
- Cancer imaging by optical coherence tomography: preclinical progress and clinical potential (2012) (256)
- Physiologically based pharmacokinetic model for specific and nonspecific monoclonal antibodies and fragments in normal tissues and human tumor xenografts in nude mice. (1994) (256)
- Increased survival of glioblastoma patients who respond to antiangiogenic therapy with elevated blood perfusion. (2012) (254)
- Interstitial hypertension in head and neck tumors in patients: correlation with tumor size. (1992) (254)
- Tumor Blood Flow-Characterization, Modifications, and Role in Hyperthermia (1984) (248)
- Impaired lymphatic contraction associated with immunosuppression (2011) (243)
- Quantitation and physiological characterization of angiogenic vessels in mice: effect of basic fibroblast growth factor, vascular endothelial growth factor/vascular permeability factor, and host microenvironment. (1996) (240)
- Dual inhibition of Ang-2 and VEGF receptors normalizes tumor vasculature and prolongs survival in glioblastoma by altering macrophages (2016) (239)
- Solid stress and elastic energy as measures of tumour mechanopathology (2016) (238)
- A genetic Xenopus laevis tadpole model to study lymphangiogenesis (2005) (236)
- Interstitial hypertension in superficial metastatic melanomas in humans. (1991) (233)
- Active versus passive mechanisms in metastasis: do cancer cells crawl into vessels, or are they pushed? (2007) (233)
- Role of eNOS in neovascularization: NO for endothelial progenitor cells. (2004) (232)
- Effect of host microenvironment on the microcirculation of human colon adenocarcinoma. (1997) (231)
- Vascular permeability in a human tumour xenograft: molecular charge dependence (2000) (222)
- Normalizing Function of Tumor Vessels: Progress, Opportunities, and Challenges. (2019) (222)
- YAP/TAZ Orchestrate VEGF Signaling during Developmental Angiogenesis. (2017) (216)
- Blocking CXCR4 alleviates desmoplasia, increases T-lymphocyte infiltration, and improves immunotherapy in metastatic breast cancer (2019) (216)
- Tumor angiogenesis and interstitial hypertension. (1996) (214)
- Noninvasive measurement of microvascular and interstitial oxygen profiles in a human tumor in SCID mice. (1994) (213)
- p53 Controls Radiation-Induced Gastrointestinal Syndrome in Mice Independent of Apoptosis (2009) (213)
- Magneto-Fluorescent Core-Shell Supernanoparticles (2014) (212)
- Microvascular permeability of albumin, vascular surface area, and vascular volume measured in human adenocarcinoma LS174T using dorsal chamber in SCID mice. (1993) (212)
- Physical traits of cancer (2020) (212)
- Vessel Architectural Imaging Identifies Cancer Patient Responders to Anti-angiogenic Therapy (2013) (211)
- Targeting Placental Growth Factor/Neuropilin 1 Pathway Inhibits Growth and Spread of Medulloblastoma (2013) (209)
- A mouse-human phase 1 co-clinical trial of a protease-activated fluorescent probe for imaging cancer (2016) (207)
- Fractal Characteristics of Tumor Vascular Architecture During Tumor Growth and Regression (1997) (203)
- During angiogenesis, vascular endothelial growth factor regulate natural killer cell adhesion to tumor endothelium (1996) (201)
- Design considerations for nanotherapeutics in oncology. (2015) (201)
- Vasculogenic mimicry: how convincing, how novel, and how significant? (2000) (198)
- Enhancement of fluid filtration across tumor vessels: implication for delivery of macromolecules. (1999) (196)
- Glioblastoma recurrence after cediranib therapy in patients: lack of "rebound" revascularization as mode of escape. (2011) (195)
- Role of vascular density and normalization in response to neoadjuvant bevacizumab and chemotherapy in breast cancer patients (2015) (194)
- Genetic evidence for a tumor suppressor role of HIF-2alpha. (2005) (192)
- Fluorescence photobleaching with spatial Fourier analysis: measurement of diffusion in light-scattering media. (1993) (189)
- Interstitial hypertension in carcinoma of uterine cervix in patients: possible correlation with tumor oxygenation and radiation response. (1991) (188)
- Effect of transvascular fluid exchange on pressure-flow relationship in tumors: a proposed mechanism for tumor blood flow heterogeneity. (1996) (185)
- Diffusion and partitioning of proteins in charged agarose gels. (1995) (181)
- VEGF inhibitors in the treatment of cerebral edema in patients with brain cancer (2009) (181)
- Targeting the renin-angiotensin system to improve cancer treatment: Implications for immunotherapy (2017) (181)
- Increase in tumor-associated macrophages after antiangiogenic therapy is associated with poor survival among patients with recurrent glioblastoma. (2013) (179)
- Cell-surface sensors for real-time probing of cellular environments. (2011) (177)
- Geometric resistance to blood flow in solid tumors perfused ex vivo: effects of tumor size and perfusion pressure. (1989) (177)
- Biodistribution of monoclonal antibodies: scale-up from mouse to human using a physiologically based pharmacokinetic model. (1995) (174)
- InAs(ZnCdS) quantum dots optimized for biological imaging in the near-infrared. (2009) (174)
- Interstitial fluid pressure in intracranial tumours in patients and in rodents. (1997) (174)
- Response criteria for glioma (2008) (173)
- Differential effects of sorafenib on liver versus tumor fibrosis mediated by stromal‐derived factor 1 alpha/C‐X‐C receptor type 4 axis and myeloid differentiation antigen–positive myeloid cell infiltration in mice (2014) (171)
- Engineering and physical sciences in oncology: challenges and opportunities (2017) (170)
- Lessons from multidisciplinary translational trials on anti-angiogenic therapy of cancer (2008) (170)
- Water channel (aquaporin 1) expression and distribution in mammary carcinomas and glioblastomas. (1999) (169)
- Two-photon fluorescence correlation microscopy reveals the two-phase nature of transport in tumors (2004) (169)
- Role of host microenvironment in angiogenesis and microvascular functions in human breast cancer xenografts: mammary fat pad versus cranial tumors. (2002) (168)
- What brings pericytes to tumor vessels? (2003) (167)
- Role of nitric oxide in angiogenesis and microcirculation in tumors (1998) (167)
- NO mediates mural cell recruitment and vessel morphogenesis in murine melanomas and tissue-engineered blood vessels. (2005) (167)
- Endothelial focal adhesion kinase mediates cancer cell homing to discrete regions of the lungs via E-selectin up-regulation (2011) (166)
- Direct evidence that bevacizumab, an anti-VEGF antibody, up-regulates SDF1alpha, CXCR4, CXCL6, and neuropilin 1 in tumors from patients with rectal cancer. (2009) (166)
- Imaging angiogenesis and the microenvironment (2008) (165)
- Diffusion anisotropy in collagen gels and tumors: the effect of fiber network orientation. (2010) (164)
- Sparse initial entrapment of systemically injected Salmonella typhimurium leads to heterogeneous accumulation within tumors. (2003) (164)
- Role of nitric oxide in tumor microcirculation. Blood flow, vascular permeability, and leukocyte-endothelial interactions. (1997) (163)
- Anti-VEGF therapy induces ECM remodeling and mechanical barriers to therapy in colorectal cancer liver metastases (2016) (162)
- Evidence for incorporation of bone marrow-derived endothelial cells into perfused blood vessels in tumors. (2006) (160)
- The Current Landscape of Immune Checkpoint Blockade in Hepatocellular Carcinoma: A Review. (2020) (160)
- CCR2 inhibition reduces tumor myeloid cells and unmasks a checkpoint inhibitor effect to slow progression of resistant murine gliomas (2019) (156)
- Vascular accumulation of a novel photosensitizer, MV6401, causes selective thrombosis in tumor vessels after photodynamic therapy. (2002) (155)
- Peritumor Lymphatics Induced by Vascular Endothelial Growth Factor-C Exhibit Abnormal Function (2004) (154)
- Transmural coupling of fluid flow in microcirculatory network and interstitium in tumors. (1997) (153)
- Robust 3-D Modeling of Vasculature Imagery Using Superellipsoids (2007) (153)
- Mechanics of interstitial-lymphatic fluid transport: theoretical foundation and experimental validation. (1999) (152)
- Perivascular nitric oxide gradients normalize tumor vasculature (2008) (151)
- Scaling rules for diffusive drug delivery in tumor and normal tissues (2011) (149)
- Transport of fluid and macromolecules in tumors. IV. A microscopic model of the perivascular distribution. (1991) (149)
- Moisture dependent physical properties of dried pomegranate seeds (Anardana) (2006) (149)
- Effect of radiation on interstitial fluid pressure and oxygenation in a human tumor xenograft. (1996) (148)
- Direct in vivo measurement of targeted binding in a human tumor xenograft. (1997) (148)
- Anti-vascular endothelial growth factor treatment normalizes tuberculosis granuloma vasculature and improves small molecule delivery (2015) (148)
- Antiangiogenics: the potential role of integrating this novel treatment modality with chemoradiation for solid cancers. (2007) (147)
- Matrix metalloproteinases-1 and -8 improve the distribution and efficacy of an oncolytic virus. (2007) (145)
- In vivo wide-area cellular imaging by side-view endomicroscopy (2010) (145)
- A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment. (2018) (145)
- Viscous resistance to blood flow in solid tumors: effect of hematocrit on intratumor blood viscosity. (1989) (143)
- Intratumoral lymphatic vessels: a case of mistaken identity or malfunction? (2002) (143)
- Transport in lymphatic capillaries. I. Macroscopic measurements using residence time distribution theory. (1996) (140)
- Lessons from anti-vascular endothelial growth factor and anti-vascular endothelial growth factor receptor trials in patients with glioblastoma. (2015) (139)
- Generation of functionally competent and durable engineered blood vessels from human induced pluripotent stem cells (2013) (138)
- Performance evaluation of an inclined multi-pass solar air heater with in-built thermal storage on deep-bed drying application (2004) (138)
- Compression of pancreatic tumor blood vessels by hyaluronan is caused by solid stress and not interstitial fluid pressure. (2014) (138)
- Losartan treatment enhances chemotherapy efficacy and reduces ascites in ovarian cancer models by normalizing the tumor stroma (2019) (137)
- A metastasis map of human cancer cell lines (2020) (136)
- Obesity promotes resistance to anti-VEGF therapy in breast cancer by up-regulating IL-6 and potentially FGF-2 (2018) (136)
- Macro- and Microscopic Fluid Transport in Living Tissues: Application to Solid Tumors (1997) (136)
- A Phase II and Biomarker Study of Ramucirumab, a Human Monoclonal Antibody Targeting the VEGF Receptor-2, as First-Line Monotherapy in Patients with Advanced Hepatocellular Cancer (2013) (135)
- Intracellular magnetic labeling of lymphocytes for in vivo trafficking studies. (1998) (135)
- Tumor necrosis factor alpha-induced leukocyte adhesion in normal and tumor vessels: effect of tumor type, transplantation site, and host strain. (1995) (135)
- VEGF-targeted cancer therapy strategies: current progress, hurdles and future prospects. (2007) (135)
- In vivo imaging of tumors. (2010) (135)
- Differential CD146 expression on circulating versus tissue endothelial cells in rectal cancer patients: implications for circulating endothelial and progenitor cells as biomarkers for antiangiogenic therapy. (2006) (134)
- Interstitial fluid pressure in solid tumors following hyperthermia: possible correlation with therapeutic response. (1992) (134)
- Simultaneous measurement of RBC velocity, flux, hematocrit and shear rate in vascular networks in vivo (2010) (134)
- Phase II study of imatinib mesylate for recurrent meningiomas (North American Brain Tumor Consortium study 01-08). (2009) (134)
- Effect of bivalent interaction upon apparent antibody affinity: experimental confirmation of theory using fluorescence photobleaching and implications for antibody binding assays. (1992) (133)
- Combined targeting of HER2 and VEGFR2 for effective treatment of HER2-amplified breast cancer brain metastases (2012) (133)
- A sensitive in vivo model for quantifying interstitial convective transport of injected macromolecules and nanoparticles. (2006) (133)
- Effect of vascular endothelial growth factor on cultured endothelial cell monolayer transport properties. (2000) (132)
- Mechanisms of enhanced drug delivery in brain metastases with focused ultrasound-induced blood–tumor barrier disruption (2018) (131)
- Adapalene loaded solid lipid nanoparticles gel: an effective approach for acne treatment. (2014) (131)
- Onset of abnormal blood and lymphatic vessel function and interstitial hypertension in early stages of carcinogenesis. (2006) (130)
- Combining microenvironment normalization strategies to improve cancer immunotherapy (2020) (130)
- Dual Programmed Death Receptor‐1 and Vascular Endothelial Growth Factor Receptor‐2 Blockade Promotes Vascular Normalization and Enhances Antitumor Immune Responses in Hepatocellular Carcinoma (2020) (130)
- Tumor oxygenation in hormone-dependent tumors during vascular endothelial growth factor receptor-2 blockade, hormone ablation, and chemotherapy. (2000) (129)
- Antiangiogenic therapy for normalization of atherosclerotic plaque vasculature: a potential strategy for plaque stabilization (2007) (129)
- Infiltrative patterns of glioblastoma spread detected via diffusion MRI after treatment with cediranib. (2010) (127)
- In vivo imaging of extracellular matrix remodeling by tumor-associated fibroblasts (2009) (127)
- Taming vessels to treat cancer. (2008) (127)
- Role of erythrocytes in leukocyte-endothelial interactions: mathematical model and experimental validation. (1996) (127)
- Endothelial nitric oxide synthase mediates lymphangiogenesis and lymphatic metastasis. (2009) (127)
- Angiopoietin-2 Interferes with Anti-VEGFR2–Induced Vessel Normalization and Survival Benefit in Mice Bearing Gliomas (2010) (126)
- Using tumour phylogenetics to identify the roots of metastasis in humans (2015) (125)
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- Development of flaxseed fortified rice – corn flour blend based extruded product by response surface methodology (2015) (14)
- Normalizing tumor microenvironment with nanomedicine and metronomic therapy to improve immunotherapy (2022) (14)
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- Vascular Endothelial Growth Factor (VEGF)-C Differentially Affects Tumor Vascular Function and Leukocyte Recruitment: Role of VEGF-Receptor 2 and Host VEGF-A 1 (2001) (13)
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- Temperature distributions in normal and neoplastic tissues during hyperthermia: lumped parameter analysis☆ (1979) (11)
- Characterization of blood vessels in brain autopsies of GBM patients who received antiangiogenic treatment (2008) (11)
- Effect of basic fibroblast growth factor on angiogenesis and growth of isografted bone: quantitative in vitro-in vivo analysis in mice. (1997) (11)
- Retrospective analysis of patterns of recurrence seen on MRI in patients with recurrent glioblastoma multiforme treated with bevacizumab plus irinotecan (2008) (11)
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- Advances in Brief Hypoxia and Acidosis Independently UpRegulate Vascular Endothelial Growth Factor Transcription in Brain Tumors in Vivo 1 (2001) (10)
- Potentially curative combination of TGF-b1 inhibitor losartan and FOLFIRINOX (FFX) for locally advanced pancreatic cancer (LAPC): R0 resection rates and preliminary survival data from a prospective phase II study. (2018) (10)
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- Abstract LB-247: A multidisciplinary phase II study of AZD2171 (cediranib), an oral pan-VEGF receptor tyrosine kinase inhibitor, in patients with recurrent glioblastoma (2008) (10)
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- Anti-VEGF treatment improves neurological function in tumors of the nervous system (2018) (9)
- Probing tumor microenvironment in patients with newly diagnosed glioblastoma during chemoradiation and adjuvant temozolomide with functional MRI (2018) (9)
- Mammary fat pad tumor preparation in mice. (2012) (9)
- Transparent Window Models and Intravital Microscopy: Imaging Gene Expression, Physiological Function and Therapeutic Effects in Tumors (2011) (9)
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- Visualizing anti-tumor immune responses in vivo (2009) (8)
- EFFECT OF CERTAIN POST-HARVEST TREATMENTS ON SHELF LIFE OF STRAWBERRY CV. CHANDLER (2005) (7)
- Clinical, pharmacodynamic (PD), and pharmacokinetic (PK) evaluation of cediranib in advanced hepatocellular carcinoma (HCC): A phase II study (CTEP 7147). (2012) (7)
- Phosphorus solubilising biofertilisers in the whirlpool of rock phosphate - challenges and opportunities. (2000) (7)
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- Angiotensin Blockade Modulates the Activity of PD1/L1 Inhibitors in Metastatic Urothelial Carcinoma. (2021) (6)
- Intratumour temperature distributions during hyperthermia (1980) (6)
- P39 08 TP – INTERSTITIAL HYPERTENSION IN HUMAN PRIMARY AND METASTATIC TUMORS (1991) (6)
- Influence of the site of human gallbladder xenograft (Mz-ChA-1) on angiogenesis at the distant site. (2004) (6)
- From the Guest Editors: Role of Tumor Microenvironment in Tumor Progression and Treatment Response: A 30 Years' Journey. (2015) (6)
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- 1054 The correlation between fractionated TCD50 and different predictive radiobiologic parameters of nine human tumor xenografts into nude mice (1995) (6)
- Reinstating Structural Stability of Castor Oil based Flexible Polyurethane Foam using Glycerol (2020) (6)
- Closing the gap: astrocytes and brain metastasis (2016) (6)
- Pharmacokinetics of methotrexate in leukemia cells: Effect of dose and mode of injection (1978) (6)
- Two-compartment model for plasma pharmacokinetics in individual blood vessels (1984) (6)
- Kinetics of interleukin-2 induced changes in rigidity of human natural killer cells (1992) (6)
- Extravasation and Interstitial Transport in Tumors (1993) (6)
- Vascular dysfunction promotes regional hypoxia after bevacizumab therapy in recurrent glioblastoma patients (2020) (6)
- Dehydration characteristics of spinach in an air recirculatory tray dryer (2003) (5)
- Optimization of an enzyme assisted banana pulp clarification process. (2014) (5)
- Characterization techniques for nanoparticulate carriers (2012) (5)
- Formulation of Therapeutic Proteins: Strategies for Developing Oral Protein Formulations (2019) (5)
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- Correspondence re: S. Maula et al., intratumoral lymphatics are essential for the metastatic spread and prognosis in squamous cell carcinoma of the head and neck. Cancer Res., 63: 1920-1926, 2003. (2003) (5)
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- Molecular Mechanisms and Future Implications of VEGF/VEGFR in Cancer Therapy. (2022) (5)
- Interstitial transport in tumors (1987) (5)
- The blood–brain barrier and blood–tumour barrier in brain tumours and metastases (2019) (5)
- ANALYSIS OF TRANSIENT TEMPERATURE DISTRIBUTIONS IN A PERFUSED MEDIUM DUE TO A SPHERICAL HEAT SOURCE WITH APPLICATION TO HEAT TRANSFER IN TUMORS: HOMOGENEOUS AND INFINITE MEDIUM (1980) (5)
- A Phase II study of cabozantinib for metastatic triple-negative breast cancer (TNBC). (2015) (4)
- Kinetics of vascular normalisation by VEGFR2 blockade governs brain tumour response to radiation: role of angiopoietin-1 and matrix metalloproteinases (2005) (4)
- In vivo pharmacokinetics of triazinate in L-1210 and W-256 cells. (1982) (4)
- Effects of hyperthermia and hyperglycemia on the metastases formation and on survival of rat bearing W256 carcinosarcoma. (1982) (4)
- Measuring interstitial diffusion, convection, and binding parameters in mouse tumors. (2013) (4)
- Anti-VEGFR-3 therapy and lymph node metastasis [corrected]. (2007) (4)
- Impact of renin-angiotensin system inhibitors on outcomes in patients with metastatic renal cell carcinoma treated with immune-checkpoint inhibitors. (2022) (4)
- A Validated High-Performance Liquid Chromatography-Tandem Mass Spectrometric ( Lc-Ms / Ms ) Method for Simultaneous Determination of R ( + )-Ketorolac and S ( − )-Ketorolac in Human Plasma and Its Application to a Bioequivalence Study (2014) (4)
- Lymphangiography of the mouse ear. (2012) (4)
- Mechanistic model for booster doses effectiveness in healthy, cancer, and immunosuppressed patients infected with SARS-CoV-2 (2022) (4)
- Antibody-based therapies for the treatment of brain metastases from HER2-positive breast cancer: time to rethink the importance of the BBB? (2017) (4)
- Angiogenesis in Solid Tumors (2007) (4)
- Increased CD8+ T-Cell Infiltration and Efficacy for Multikinase Inhibitors after PD-1 Blockade in Hepatocellular Carcinoma. (2022) (4)
- Abstract 3975: Matrix-depleting anti-hypertensives decompress tumor blood vessels and improve perfusion in patients with glioblastomas receiving anti-angiogenic therapy (2016) (4)
- Normalization of Tumor Vasculature and Alleviation of Edema by AZD2171, A Pan-VEGF Receptor Tyrosine Kinase Inhibitor in Glioblastoma Patients (2007) (4)
- Oncotic Pressure in Solid Tumors Is Elevated 1 (2000) (4)
- Measurement of interstitial fluid pressure (IFP) and circulating biomarkers in soft tissue sarcoma (STS): An exploratory phase II clinical and correlative study of sorafenib (SOR) in patients with refractory STS (NCI Protocol 6948). (2010) (4)
- Pharmacokinetics of 2-pyridyl acetic acid, a major betahistine metabolite in healthy Indian volunteers (2009) (3)
- Nanoparticles as drug carriers (2012) (3)
- Corneal pocket assay in rabbits. (2012) (3)
- Does DSC-derived CA extravasation correlate with DCE Ktrans ? (2010) (3)
- Measurement of physiological parameters in tumors in vivo using MPLSM (2001) (3)
- Emerging Trends in Nanotechnology for Diagnosis and Therapy of Lung Cancer (2018) (3)
- In vivo assessment of the effects of bevacizumab in advanced non-small cell lung cancer (NSCLC). (2010) (3)
- Drug discovery and delivery. (1995) (3)
- Impact of adjuvant anti-VEGF therapy on treatment-related pseudoprogression in patients with newly diagnosed glioblastoma receiving chemoradiation with or without anti-VEGF therapy. (2012) (3)
- Differential circulation kinetics during antiangiogenic therapy of four distinct blood cell populations expressing endothelial markers. (2006) (3)
- Smooth sailing for immunotherapy for unresectable stage III non-small cell lung cancer: the PACIFIC study. (2018) (3)
- Effect of microwave roasting on cyanogenic glycosides and nutritional composition of flax seed (2014) (3)
- Notch leads lymphatics and links them to blood vessels. (2010) (3)
- Abstract LB-213: Plasma soluble VEGFR1 is a potential dual biomarker of response and toxicity for bevacizumab with chemoradiation in locally advanced rectal cancer (2010) (3)
- Phase I study of plerixafor and bevacizumab in recurrent high-grade glioma. (2014) (3)
- Post harvest microbial losses in distant marketing of Kinnow. (2004) (3)
- A Physical View of Cancer. (2018) (3)
- Measurements of Diffusion Coefficients in Spontaneous Human Tumors. (2000) (3)
- The pharmacodynamic equivalence of Orlistat 60 mg capsule. An open label, balanced, randomized, multiple-dose, cross-over pharmacodynamic end-point bioequivalence study in healthy, adult, human Asian Indian subjects under fed conditions (2013) (3)
- Abstract 548: Multistage nanoparticle delivery system for deep penetration into solid tumor (2011) (3)
- Determination of pharmacokinetics of itraconazole in healthy Indian subjects under fed condition and incurred sample analysis using a validated liquid chromatography tandem mass spectrometric method (2012) (3)
- Angiogenesis in Development, Disease, and Regeneration (2009) (3)
- Effect of cabozantinib treatment on circulating immune cell populations in patients with metastatic triple-negative breast cancer (TNBC). (2016) (3)
- INCREASED PERFUSION DUE TO VASCULAR NORMALIZATION IMPROVES OXYGENATION AND SURVIVAL IN GLIOBLASTOMA PATIENTS TREATED WITH CEDIRANIB WITH OR WITHOUT CHEMORADIATION (2014) (2)
- Intratumor pharmacokinetics of gemcitabine (dFdC) in ex vivo perfused small cell lung cancer. A new model for pharmacological and metabolic studies in human tumor xenografts (1994) (2)
- Evidence for bone marrow-derived endothelial cells incorporation into perfused blood vessels in tumors (2006) (2)
- Abstract LB-297: Vessel architectural imaging identifies cancer patient responders to anti-angiogenic therapy. (2013) (2)
- Lessons From 30 Years of Teaching About the Microenvironment of Tumors. (2015) (2)
- The Open-Access Journal for the Basic Principles of Diffusion Theory , Experiment and Application Diffusion in Tumors and Normal Tissues (2011) (2)
- A comparative study of circulating biomarkers of anti-VEGF therapy in phase II trials in advanced hepatocellular carcinoma (HCC) patients (pts). (2014) (2)
- Hypoxia-induced DNA hypermethylation: another reason to normalize tumor vessels (2016) (2)
- Gabrb3 endothelial cell-specific knockout mice display abnormal blood flow, hypertension, and behavioral dysfunction (2022) (2)
- Limited Environmental Serine Confers Sensitivity to PHGDH Inhibition in Brain Metastasis (2020) (2)
- Closing the gap between astrocytes and brain metastasis progression. (2016) (2)
- Abstracts from the International Society for Therapeutic Ultrasound Conference 2017 (2018) (2)
- Efficacy, safety, and changes in blood markers following sunitinib monotherapy in patients with advanced hepatocellular carcinoma: Experience from a multidisciplinary Phase II study (2008) (2)
- Lymphangiography of the mouse tail. (2012) (2)
- Lung window preparation in mice. (2013) (2)
- Interstitial diffusion of macromolecules in solid tumors: Role of the interstitial matrix (2001) (2)
- Abstract 368: In vivo vessel co-option by glioma cells following chronic anti-angiogenic treatment (2010) (2)
- Author Correction: Fatty acid synthesis is required for breast cancer brain metastasis (2021) (2)
- Advancesin Brief Measurement of Capillary Filtration Coefficient in a Solid Tumor1 (1991) (2)
- Pancreatic tumor preparation in mice. (2012) (2)
- Correlation of blood and physiologic markers with effect of bevacizumab (BV) with chemoradiation therapy in rectal cancer (RC) (2008) (2)
- P39 07 TP – RELATIONSHIP BETWEEN INTERSTITIAL FLUID PRESSURE AND TUMOR OXYGENATION (1991) (2)
- Role of VEGF-Receptor 2 and Host VEGF-A Affects Tumor Vascular Function and Leukocyte Recruitment: Vascular Endothelial Growth Factor (VEGF)-C Differentially (2001) (2)
- Abstract LB-203: Obesity promotes resistance to anti-VEGF therapy in breast cancer via pro-inflammatory and angiogenic pathways (2015) (2)
- 6408 Re-use of subject-specific AIFs are warranted in longitudinal DCE-MRI (2013) (2)
- Next-generation optical imaging with short-wave infrared quantum dots. (2017) (2)
- CRITICAL ISSU-ES IN TUMOR MICROCIRCULATION, ANGIOGENESIS AND METASTASIS: BIOLOGICAL SIGNIFICANCE AND CLINICAL RELEVANCE (1993) (2)
- Normalization of Tumor Vasculature and Microenvironment by Antiangiogenic Therapies: From the Bench to Bedside and Back (2007) (2)
- Measuring interstitial pH and pO2 in mouse tumors. (2013) (2)
- Publisher Correction: A metastasis map of human cancer cell lines (2021) (2)
- Novel function of RANKL: eNOS activator (2007) (2)
- The use of elevated circulating hepatocyte growth factor (HGF) level as a potential prognostic biomarker in locally advanced pancreatic cancer. (2021) (2)
- Modes of Neovascularization in Tumors and Clinical Translation of Antiangiogenic Therapy (2014) (2)
- Design rules for cancer nanomedicines (2012) (2)
- Effect of angiotensin ii induced hypertension on tumor interstitial fluid pressure and tumor blood flow (1992) (2)
- Liver tumor preparation in mice. (2012) (2)
- Society of Surgical Oncology 64th Annual Cancer Symposium (2011) (2)
- Rabbit ear chambers. (2012) (2)
- Uncovering Tumor Biology by Intravital Microscopy (2014) (2)
- Abstract 2744: Blocking CXCR4 alleviates desmoplasia, increases T-lymphocyte infiltration, and improves immunotherapy in metastatic breast cancer (2019) (2)
- Optical Microscopy in Small Animal Research (2007) (2)
- Comparison of pharmacokinetics of citalopram in healthy Asian Indian and Mexican volunteers (2011) (2)
- Pharmacokinetic comparison and bioequivalence evaluation of losartan/ hydrochlorothiazide tablet between Asian Indian and Japanese volunteers. (2014) (2)
- Automated in vivo change analysis of tumor vasculature from two-photon confocal image time series (2003) (2)
- Regulatory aspects of nanoparticulate drug delivery systems (2012) (2)
- Strategies to minimize heterogeneity and optimize clinical trials in Acute Respiratory Distress Syndrome (ARDS): Insights from mathematical modelling (2022) (2)
- Optimization of operating parameters of a centrifugal sheller for dehusking «Jaya» variety paddy (1986) (2)
- Robust Parametric Modeling for Improved Segmentation of Complex Tumor Microvasculature from Multiphoton Microscopy Data (2004) (1)
- Publisher Correction: Engineering and physical sciences in oncology: challenges and opportunities (2018) (1)
- Tumor Microenvironment (2016) (1)
- Reply to Ciccolini et al.: Using mathematical modeling to predict response to antiangiogenic therapy in cancer patients (2015) (1)
- A Phase I Trial of TB-403 in Relapsed Medulloblastoma, Neuroblastoma, Ewing Sarcoma, and Alveolar Rhabdomyosarcoma. (2022) (1)
- A multicenter, randomized phase II study of total neoadjuvant therapy (TNT) with FOLFIRINOX (FFX) and SBRT, with or without losartan (L) and nivolumab (N) in borderline resectable (BR) and locally advanced (LA) pancreatic ductal adenocarcinoma (PDAC). (2023) (1)
- Angiogenesic profile in sporadic and NF2-related schwannomas (2008) (1)
- Mammary fat pad chamber preparation in mice. (2012) (1)
- A framework for advancing our understanding of cancer-associated fibroblasts (2020) (1)
- Evaluation of the effects of anti-VEGF therapy in a multidisciplinary phase I/II study of neoadjuvant bevacizumab with chemoradiation therapy in rectal cancer (2008) (1)
- Abstract C1: Functional normalization of the breast cancer vasculature through activation of Tie2 using a vascular-endothelial protein tyrosine phosphatase inhibitor. (2013) (1)
- Normalizing the Tumor Microenvironment for Radiosensitization (2020) (1)
- Abstract C043: Addition of losartan to FOLFORINOX and chemoradiation downregulates pro-invasion and immunosuppression-associated genes in locally advanced pancreatic cancer (2022) (1)
- Kendrick Mass Defect Variation to Decipher Isotopic Labeling in Brain Metastases Studied by Mass Spectrometry Imaging. (2021) (1)
- Abstract IA03: Antiangiogenesis strategies revisited: From starving tumors to alleviating hypoxia (2015) (1)
- Decrease in tumor interstitial fluid pressure by pentoxifylline (1992) (1)
- Implications of a granulocyte‐high glioblastoma microenvironment in immune suppression and therapy resistance† (2021) (1)
- Review Determinants of Tumor Blood Flow: A Review1 (1988) (1)
- Abstract P3-12-03: Combined targeting of HER2 and VEGFR2 for effective treatment of HER2-amplified breast cancer brain metastases. (2012) (1)
- Correlation between VEGF expression and MVD in sporadic and NF2-related schwannomas (2007) (1)
- Strategies to Minimize Heterogeneity and Optimize Clinical Trials in Acute Respiratory Distress Syndrome (ARDS): Insights from Mathematical Modeling (2021) (1)
- Use of radiation on interstitial fluid pressure (IFP) and pO2 in human tumors (1992) (1)
- Effect of antiangiogenic therapy on tumor-associated macrophages in recurrent glioblastoma. (2012) (1)
- Extravascular Diffusion in Normal and Neoplastic Tissues1 (2006) (1)
- Losartan controls immune checkpoint blocker-induced edema and improves survival in glioblastoma mouse models (2022) (1)
- Modulation of intratumoral drug delivery by the tumor microenvironment and vascular endothelial growth factor (1998) (1)
- Lung Cancer Receptors and Targeting Strategies (2019) (1)
- Chitosan Oligosaccharides: Drug and Gene Delivery (2015) (1)
- Abstract LB-363: Inhibition of placental growth factor (PlGF) leads to regression of medulloblastoma (2010) (1)
- COGNITIVE DRILL THERAPY IN MENTAL CONTAMINATION: A CASE STUDY. (2018) (1)
- TMOD-37. IN VIVO COMPRESSION AND IMAGING FOR CAUSAL STUDIES OF MECHANICAL FORCES IN THE BRAIN (2020) (1)
- Part 2: Targeting Cancer Pathways: The Tumor Microenvironment (2015) (1)
- Effect of plant growth regulators on growth and survival of strawberry runners under semi arid region of Punjab (2003) (1)
- Combined Angiotensin Receptor Blocker Losartan and the CXCR4 Inhibitor AMD3100 Increases the Efficacy of Radiotherapy in a Metastatic Osteosarcoma Mouse Model (2018) (1)
- Retraction Note: A homing system targets therapeutic T cells to brain cancer (2019) (1)
- Measuring leukocyte-endothelial interactions in mice. (2013) (1)
- Abstract CT015: A phase 1 dose escalation study of TB-403 in pediatric relapsed or refractory medulloblastoma, neuroblastoma, Ewing sarcoma, or alveolar rhabdomyosarcoma (2021) (1)
- Abstract 5008: The brain microenvironment mediates resistance in luminal breast cancer to PI3K inhibition through HER3 activation (2017) (1)
- Efficacy, safety, and changes in angiogenic markers following sunitinib monotherapy in patients with advanced hepatocellular carcinoma: Experience from a phase II study. (2007) (1)
- Multiphoton Phosphorescence Quenching Microscopy Reveals Kinetics of Tumor Oxygenation during Antiangiogenesis and Angiotensin Signaling Inhibition (2022) (1)
- Cancer Therapy : Preclinical TGF-b Blockade Controls Ascites by Preventing Abnormalization of Lymphatic Vessels in Orthotopic Human Ovarian Carcinoma Models (2011) (1)
- Surrogate biomarkers for anti-angiogenic therapy for advanced colorectal cancer (2007) (1)
- Analysis of cGMP signalling with transgenic mice expressing FRET-based cGMP sensors (2013) (1)
- Evaluation of bamboo cement bin in humid hot region. (1990) (1)
- Pharmacokinetics and Cancer Chemotherapy. Cancer Surveys: Advances and Prospects in Clinical, Epidemiological and Laboratory Oncology, Volume 17.P. Workman , M. A. Graham (1994) (1)
- 2685: Utilizing Mouse Genetics to Dissect the Cellular Target and Molecular Mechanism of Acute and Late Toxicity of Abdominal Radiation Therapy (2006) (1)
- Reply to “PET concerns in bevacizumab treatment” (2004) (1)
- Physical and mechanical properties of different ber cultivars. (2009) (1)
- INTERSTITIAL TRANSPORT IN TUMORS ROLE OF BINDING (1994) (1)
- Radiomodifying responses of vitamin E and epigallocatechin gallate supplementation during irradiation of implanted tumors. (2004) (1)
- Analysis of cGMP signalling with transgenic mice expressing FRET-based cGMP sensors (2013) (1)
- Therapeutics , Targets , and Chemical Biology Cancer Cell – Associated MT 1-MMP Promotes Blood Vessel Invasion andDistantMetastasis in Triple-NegativeMammary Tumors (2011) (1)
- A novel model to study microcirculation mediated mechanisms of radiotherapy in human tumor xenografts (1992) (1)
- Improved physiological parameters in murine & human tumors by nicotinamide (1993) (1)
- Microcirculation of Human Colon Adenocarcinoma (2007) (1)
- Abstract LB-339: Increase in tumor-associated macrophages (TAMs) after antiangiogenic therapy is associated with poor survival in recurrent glioblastoma (GBM) patients. (2013) (1)
- Abstract 898: Obesity-induced inflammation and desmoplasia promote pancreatic cancer progression and resistance to chemotherapy (2016) (1)
- Abstract A13: Endothelial podosome rosettes regulate vascular branching in tumor angiogenesis (2015) (1)
- Prevalence of metabolic syndrome in drug-naive patients with schizophrenia - (2016) (1)
- Going Beyond VEGF Pathway Inhibition for Antiangiogenic Cancer Therapy: Is Inhibition of the PP2A/B55α Complex the Answer? (2020) (1)
- The role of erythrocytes in leukocyte-endothelial interactions (1995) (1)
- A Quantitative In Vivo Model of Irradiation Effect on Lymphatic Function and Lymphangiogenesis: Implications for Radiation Induced Secondary Lymphedema (2005) (1)
- Vascular Normalization to Improve Treatment of COVID-19: Lessons from Treatment of Cancer (2021) (1)
- Vascular normalization: a strategy to recondition the tumor immune microenvironment (2013) (1)
- Hormone Ablation , and Chemotherapy Vascular Endothelial Growth Factor Receptor-2 Blockade , Tumor Oxygenation in Hormone-Dependent Tumors During Updated (2000) (1)
- Abstract 130: PF-06463922, a novel next generation ALK/ROS1 inhibitor, overcomes resistance to 1st and 2nd generation ALK inhibitors in pre-clinical models (2015) (1)
- Physiologically Based Pharmacokinetic Model for Specific and Nonspecific Monoclonal Antibodies and Fragments in Normal Tissues and Human Tumor Xenografts in Nude Mice1 (2006) (1)
- Angiotensin system inhibitors during induction chemotherapy for esophageal adenocarcinoma: Analysis of survival. (2018) (1)
- Radiopharmaceuticals : Preparation, Evaluation And Applications (2003) (1)
- Abstract PR06: VEGF-targeted therapy induces extracellular matrix remodeling and increases mechanical barriers to therapy in colorectal cancer liver metastases (2017) (1)
- A phase I study of cediranib plus whole-brain radiation therapy in patients with brain metastases from non-small cell lung cancer. (2010) (1)
- Abstract IA4: Normalizing the tumor microenvironment to enhance therapeutic outcome (2011) (1)
- A phase II study of neoadjuvant bevacizumab and radiation therapy for resectable soft tissue sarcomas. (2010) (1)
- S1.2. New insights into the structure of tumor vasculature: From fractal dimensions to intussusception (1995) (1)
- Erratum: Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis (Nature (1998) 394 (485-490)) (1998) (1)
- Caregiver Burden and Expressed Emotion in Caregivers of Patients with Schizophrenia (2016) (1)
- Laser speckle micro rheology for micro-mechanical mapping of bio-materials (Conference Presentation) (2016) (1)
- Advances in Brief Vascular Endothelial Growth Factor ( VEGF ) Modulation by Targeting Hypoxia-inducible Factor-1 a 3 Hypoxia Response Element 3 VEGF Cascade Differentially Regulates Vascular Response and Growth Rate in Tumors 1 (2000) (1)
- The orthotopic microenvironment promotes tumor growth and VEGF121 expression in human pancreatic adenocarcinoma (2000) (1)
- Determinants of Tumor Blood Flow: A Review1 (2006) (1)
- MetMap: a map of metastatic potential of human cancer cell lines (2020) (1)
- Perspectives in Cancer Research Fractals and Cancer 1 (2000) (1)
- Letter to the editor regarding recent article by Wu et al. [J. Theor. Biol. 355 (2014) pp. 194-207]. (2014) (0)
- A homing system targets therapeutic T cells to brain cancer (2018) (0)
- Abstract C57: The role of stromal cells in tumor metastases (2009) (0)
- NIMG-108. PHYSICAL STRESSES IN BRAIN TUMORS (2022) (0)
- Characterisation of Diffusion in Collagen Matrices. (1999) (0)
- P39 13 TP – GEOMETRIC RESISTANCE AND VASCULAR ARCHITECTURE OF HUMAN TUMORS (1991) (0)
- P93 HYPOXIA UNDER SORAFENIB TREATMENT UPREGULATES SDF1a/CXCR4 RESULTING IN MYOFIBROBLAST ACTIVATION, GR1+ CELL INFILTRATION, AND DESMOPLASIA IN HEPATOCELLULAR CARCINOMA (2014) (0)
- Restoring perivascular nitric oxide gradients normalizes breast cancer vasculature (2014) (0)
- Chemotherapy elicits pro-metastatic extracellular vesicles in breast cancer models (2018) (0)
- Abstract S01-02: Optimizing treatment for COVID-19 using computational modeling: Implications for cancer patients (2020) (0)
- HCC resistance to sorafenib can be caused by hypoxia-induced SDF1a/CXCR4 upregulation leading to tumor desmoplasia and GR1+ cell infiltration (2014) (0)
- In Vivo Fluorescence Cellular Imaging by Side-view Endomicroscopy (2010) (0)
- Neoadjuvant Bevacizumab Does Not Appear to Contribute to Postoperative Complications after Surgery of Rectal Cancer (2009) (0)
- Antibody targeting of endothelial Tie1 receptor as an anti-angiogenic sensitizer in tumor therapy (2008) (0)
- Abstract 3987: Solid stress and elastic energy as measures of tumor mechanopathology (2017) (0)
- MRS and MRI Studies of the Structure and Function of Tumor Interstitial Matrix. (1998) (0)
- Non-invasive monitoring of chronic liver disease via near-infrared and shortwave-infrared imaging of endogenous lipofuscin (2020) (0)
- Antibody-mediated delivery of viral epitopes to tumors harnesses CMV-specific T cells for cancer therapy (2020) (0)
- Critical issues in tumor microcirculation, angiogenesis and metastasis: Biological significance and clinical relevance (2004) (0)
- Antiangiogenic Therapy for Malignant Gliomas (2017) (0)
- Effect of Glucose and Galactose on Microcirculatory Flow in Normal and Neoplastic Tissues in Rabbits 1 (2006) (0)
- Complexity analysis of angiogenesis vasculature (2005) (0)
- Combined blockade of VEGF, Angiopoietin-2, and PD1 reprograms glioblastoma endothelial cells into quasi-antigen-presenting cells (2022) (0)
- Optical methods in vascular biology and medicine. (2010) (0)
- Phase II and Biomarker Study of Cabozantinib in Metastatic Triple-Negative Breast Cancer Patients. (2021) (0)
- 683P Impact of renin-angiotensin system inhibitors (RASi) on outcomes in patients with metastatic renal cell carcinoma (mRCC) treated with immune checkpoint inhibitors (ICI) (2021) (0)
- Impact of angiotensin inhibitors on pathologic complete response with neoadjuvant chemotherapy (NAC) for muscle-invasive bladder cancer (MIBC). (2021) (0)
- Mathematical Model of Oxygen Transport in Tuberculosis Granulomas (2015) (0)
- A Novel Culture System of Human ES Cells for High Efficient Hematopoietic and Endothelial Differentiation. (2005) (0)
- Genetic, tissue, and plasma biomarkers of outcomes from a prospective study of neoadjuvant short course proton-based chemoradiation for resectable pancreatic ductal adenocarcinoma (PDAC). (2013) (0)
- Systemic levels of VEGF and endostatin are influenced by tumor, host, and treatment factors (2002) (0)
- Value of correlative biomarkers in understanding tumor biology (2016) (0)
- Advances in Brief Vascular Endothelial Growth Factor Receptor-2-blocking Antibody Potentiates Radiation-induced Long-Term Control of Human Tumor Xenografts 1 (2000) (0)
- Cationic Nanoparticles Have Superior Transvascular Flux into Solid Tumors: Insights from a Mathematical Model (2012) (0)
- Humans Interstitial Hypertension in Superficial Metastatic Melanomas in (1991) (0)
- Abstract C263: mTOR inhibition specifically sensitizes colorectal cancers with KRAS or BRAF mutations to BCL-2/BCL-XL inhibition by suppressing MCL-1. (2013) (0)
- Critical issues in tumor microcirculation, angiogenesis and metastasis (2004) (0)
- Correlation of some demographic parameters with clinical parameters of metabolic syndrome, bipolar affective disorders, and its therapeutics (2017) (0)
- Solid force on normal tissue Cancer cell Collagen Stromal cell Hyaluronan Endothelial cell High blood flow Blood stasis (2014) (0)
- Abstract LB557: Multiphoton phosphorescence quenching microscopy reveals kinetics of tumor oxygenation during anti-angiogenesis and angiotensin signaling inhibition (2022) (0)
- ACTR-76. FINAL RESULTS FROM A PHASE I STUDY OF PLERIXAFOR AND BEVACIZUMAB IN RECURRENT HIGH-GRADE GLIOMA (2017) (0)
- Methods to improve anti-angiogenic therapy and immunotherapy (2018) (0)
- TNF-a-Activated Endothelium: Augmentation by Erythrocytes (2005) (0)
- Radiopharmaceuticals: Preparation, evaluation and applications(Review). (2003) (0)
- CADD-32. MECHANISMS OF ENHANCED DRUG DELIVERY IN BRAIN TUMORS WITH FOCUSED ULTRASOUND-INDUCED TRANSIENT BLOOD-TUMOR BARRIER DISRUPTION (2018) (0)
- Circulating oncometabolite 2-hydroxyglutarate (2HG) as a potential surrogate biomarker in patients with isocitrate dehydrogenase mutant (IDHm) intrahepatic cholangiocarcinoma (ICC). (2013) (0)
- AT-37PHASE I STUDY OF PLERIXAFOR AND BEVACIZUMAB IN RECURRENT HIGH-GRADE GLIOMA (2014) (0)
- Abstract B32: TGF-β blockade improves the distribution and efficacy of chemotherapeutic agent in breast carcinoma (2010) (0)
- II . ROLE OF ABNORMAL VASCULATURE IN TUMOR PROGRESSION AND TREATMENT RESISTANCE A . The Abnormal Structure of Tumor Vasculature (2011) (0)
- Validation of different MRI vessel caliber index models with in-vivo 2-photon microscopy measurements of vessel caliber in a U87 mouse brain tumor model (2007) (0)
- 1463 Addition of losartan to FOLFORINOX and chemoradiation downregulates pro-invasion and immunosuppression associated genes in locally advanced pancreatic cancer (2022) (0)
- Abstract B79: CXCR4 inhibition facilitates anti-PD-1 immunotherapy by reprogramming the tumor microenvironment during sorafenib treatment in hepatocellular carcinoma (2015) (0)
- Erratum: Quantum dot/antibody conjugates for in vivo cytometric imaging in mice (Proceedings of the National Academy of Sciences of the United States of America (2015) 112 (1350-1355) doi: 10.1073/pnas.1421632111) (2015) (0)
- Abstract A64: Mechanistic model for booster doses effectiveness in healthy, cancer and immunosuppressed patients infected with SARS-CoV-2 (2022) (0)
- 1224 POSTER Docetaxel Delivery Mediated by Nanoparticles of Novel Hydrophobic Starch (2011) (0)
- Ly6C[superscript lo] monocytes drive immunosuppression and confer resistance to anti-VEGFR2 cancer therapy (2019) (0)
- Abstract LB-81: A study of circulating biomarkers of angiogenesis and inflammation in ER+ breast cancer (BC) versus triple-negative breast cancer (TNBC) patients enrolled in a phase II study of preoperative treatment with 1 cycle of Bevacizumab followed by standard chemo (2013) (0)
- Caregiver Burden and Expressed Emotion in Caregivers of Patients with Schizophrenia (2016) (0)
- Primary tumor irradiation affects levels of systemic angiogenic agents: potential roles for both tumor and host tissues (2001) (0)
- Chemical genomics and molecular medicine (2009) (0)
- erratum Perinuclear localizationof chromatin facilitates transcriptional silencing (0)
- P19 02 MP – PERIVASCULAR LOCALIZATION OF ANTIBODY IN A HUMAN COLON CARCINOMA XENOGRAFT: MACRO- AND MICRO-AUTORADIOGRAPHY (1991) (0)
- Probing tumor microenvironment in patients with newly diagnosed glioblastoma during chemoradiation and adjuvant temozolomide with functional MRI (2018) (0)
- IMST-40. REPROGRAMMING OF THE TUMOR IMMUNE MICROENVIRONMENT BY AN ANG-2/VEGF BISPECIFIC ANTIBODY DELAYS TUMOR GROWTH AND PROLONGS SURVIVAL IN PRECLINICAL GBM MODELS (2016) (0)
- Macromolecular transport in the initial lymphatics: Characterization using RTD theory and FRAP (1995) (0)
- Dual endothelin receptor inhibition enhances T-DM1 efficacy in brain metastases from HER2-positive breast cancer (2019) (0)
- Abstract A67: Reconditioning the tumor immune microenvironment for a breast cancer vaccine therapy. (2013) (0)
- Abstract 4811: Compression-induced cell distension stimulates coordinated migration of mammary carcinoma cells (2010) (0)
- Abstract IA020: Improving treatment of primary and metastatic brain tumors: Emerging insights and novel strategies (2023) (0)
- Impact of angiotensin-converting enzyme inhibitors (ACEi) on pathologic complete response with neoadjuvant chemotherapy (NAC) for muscle-invasive bladder cancer (MIBC). (2022) (0)
- Tumor Cell Death-Inducing Pretreatments Enhance the Distribution and Efficacy of Oncolytic Herpes Simplex Virus in Solid Tumors (2002) (0)
- TUMOR BLOOD FLOW AND pH DURING HYPERGLYCEMIA effects of hyperglycemia in murine radiation-induced fibrosarcoma a “P NMR investigation (0)
- Tumor-host interaction modulates production of antiangiogenic factors from human pancreatic cancer (2001) (0)
- Tumor as an aberrant organ: Insights from intravital microscopy. (2004) (0)
- Consensus guidelines for the use and interpretation of angiogenesis assays (2018) (0)
- Residual Stresses in Solid Tumors: Implications to Tumor Growth and Drug Delivery (2012) (0)
- BSCI-10. NEUROLOGICAL DYSFUNCTION CAUSED BY BRAIN TUMOR-GENERATED SOLID STRESS IS REVERSED BY LITHIUM (2019) (0)
- Early toxicity of sunitinib as a potential predictive biomarker in advanced hepatocellular carcinoma (HCC) patients. (2010) (0)
- Abstract P6-17-02: Ado-trastuzumab emtansine (T-DM1) is effective against established HER2-positive breast cancer brain metastases in mice (2016) (0)
- Abstract LB-76: Tissue biomarkers and interstitial fluid pressure in a phase II study of preoperative (preop) bevacizumab (bev) followed by dose-dense doxorubicin (A)/cyclophosphamide (C)/paclitaxel (T) in combination with bev in HER2-negative operable breast cancer (BC) (2013) (0)
- ANGI-04Olig2 REGULATES Wnt7b EXPRESSION AND VASCULATURE CHARACTERISTICS IN GLIOMA (2015) (0)
- Publisher Correction: Probing tumor microenvironment in patients with newly diagnosed glioblastoma during chemoradiation and adjuvant temozolomide with functional MRI (2019) (0)
- NCOG-44. NEUROLOGIC ASSESSMENT IN NEURO-ONCOLOGY (NANO) SCALE IN A PHASE II STUDY OF PEMBROLIZUMAB OR PEMBROLIZUMAB PLUS BEVACIZUMAB IN PATIENTS WITH RECURRENT GLIOBLASTOMA (2020) (0)
- Antiangiogenic Therapy for Normalization of Tumor Vasculature and Microenvironment (2008) (0)
- TMIC-61. LOSARTAN PREVENTS IMMUNOTHERAPY-ASSOCIATED EDEMA AND ENHANCES SURVIVAL IN GLIOBLASTOMA (2022) (0)
- Metformin reduces ECM remodeling, EMT, and metastasis in a PDAC mouse model. (2015) (0)
- Proffered Paper: Obesity-induced inflammation and desmoplasia promote pancreatic cancer progression and resistance to chemotherapy (2016) (0)
- PLACENTAL GROWTH FACTOR/NEUROPILIN 1 SIGNALING IS A THERAPEUTIC TARGET IN PEDIATRIC MEDULLOBLASTOMA (2013) (0)
- Abstract A63: Normalizing the microenvironment with metronomic nanomedicine potentiates immune checkpoint inhibition in preclincial tumor models (2022) (0)
- Abstract 3847: Metastasizing host stromal cells potentiate colonization of metastatic tumors (2010) (0)
- Micelle-Encapsulated Quantum Dot-Porphyrin Assemblies asin VivoTwo-Photon Oxygen Sensors The Harvard made this article openly available. Please share how this access benefits you. Your story matters (2016) (0)
- Bevacizumab Impact on Hearing Loss Due to Neurofibromatosis Type 2 Associated Vestibular Schwannomas and Associated Biomarkers (S34.004) (2016) (0)
- Macromolecular transport in Tumor Interstitium. (1999) (0)
- A cerebellopontine angle mouse model for the investigation of tumor biology, hearing, and neurological function in NF2-related vestibular schwannoma (2019) (0)
- Course Announcement (2004) (0)
- Abstract SY38-03: Microenvironment dictates differential responseof primary tumor versus metastases (2018) (0)
- Publisher Correction: A metastasis map of human cancer cell lines (2021) (0)
- Abstract 90: Fatty acid synthesis is required for breast cancer brain metastasis (2021) (0)
- Su1552 - RDX023-2, a Minimally Systemic, Non-Bile Acid FXR Agonist, Reduces Steatosis, Inflammation and Fibrosis in Three Mouse Models of NASH (2018) (0)
- Taxonomy of the family Arenaviridae and the order Bunyavirales: update 2018 (2018) (0)
- Development, Validation and Successful Application of an In Vitro-In Vivo Correlation Model for Sustained Release Tablets of Bupropion Hydrochloride (2017) (0)
- Taxonomy of the order Bunyavirales: second update 2018 (2019) (0)
- Minimally-Systemic TGR5 Agonist RDX009-01 Improves Hepatic Steatosis and Insulin Sensitivity in Western Diet-Fed Mice (2017) (0)
- 907 Blockade of VEGF, angiopoietin-2, and PD1 reprograms dysfunctional endothelial cells in glioblastoma to quasi-antigen-presenting cells (2022) (0)
- Course: Critical Issue in Tumor Microcirculation, Angiogenesis, and Metastasis: Biological Significane and Clinical Relevance (2004) (0)
- Abstract 1579: TGF-β blockade controls ascites by preventing abnormalization of lymphatic vessels in orthotopic human ovarian carcinoma model (2011) (0)
- Development and Validation of 'Level A' In Vitro - In Vivo Correlation for Extended Release Tablets of Lamotrigine (2016) (0)
- The Role of Mesenchymal Bone Marrow-derived Cells in Tumor Formation (2006) (0)
- Case studies: nano-systems in the market (2012) (0)
- Side-View Endomicroscopy for High-Resolution In Vivo Imaging of the Gastrointestinal Tract (2012) (0)
- Abstract A12: Microenvironmental Interleukin-6 induced activation of STAT3 signaling in medulloblastoma: Implications for molecular pathology and therapy (2016) (0)
- Retraction Note: A homing system targets therapeutic T cells to brain cancer (2019) (0)
- Electrical Self-Sensing of Pulsed Laser Ablation in Nanofiller-Modified Composites (2021) (0)
- Determination of CFB Box Dimensions for Packaging of Kinnow Fruit (2006) (0)
- The Role of Stromal Cells in Tumor Metastases. (2009) (0)
- Dormancy in Tumors Factors : A Potential Mechanism of Focal Necrosis and Local Imbalance of Proangiogenic and Antiangiogenic Updated (2000) (0)
- Reengineering the Tumor Stroma to Improve Cancer Treatment: Bench to Bedside (2016) (0)
- Abstract PO054: Improving immune checkpoint inhibition using tumor microenvironment normalization strategies: Insights from in silico analysis (2021) (0)
- ING4 is a molecular target for regulation of thebrain tumor growth and angiogenesis. (2007) (0)
- Storage studies on ber fruits (cv. Umran) in zero energy cool chamber. (2005) (0)
- Understanding the tumor immune microenvironment (TIME) for effective therapy (2018) (0)
- Abstract 2990: Antigen presentation deficiency and mesenchymal differentiation underlie resistance to immunotherapy in the murine syngeneic CT2A tumor model (2023) (0)
- A phase II study of cabozantinib (cabo) alone or in combination with trastuzumab (T) in patients (pts) with breast cancer brain metastases (BCBM). (2018) (0)
- Abstract LB226: Requirement for booster doses in healthy, cancer and immunosuppressed patients infected with the ancestral or variant SARS-CoV-2 (2022) (0)
- The intratumoral transport of large molecules in tumors is dependent on the site of tumor growth. (2000) (0)
- Edema control by anti-VEGF therapy prolongs survival despite persistent tumor growth in mice (2008) (0)
- Abstract LB-288: Restoration of peri-vascular nitric oxide gradient radio-sensitizes murine breast cancers via vascular normalization. (2011) (0)
- Multicenter, prospective, phase 2 study of maintenance bevacizumab for children and adults with NF2-related schwannomatosis and progressive vestibular schwannoma. (2023) (0)
- Author Correction: Non-invasive monitoring of chronic liver disease via near-infrared and shortwave-infrared imaging of endogenous lipofuscin (2020) (0)
- IMMU-05. DISRUPTION OF THE CCR2 CHEMOKINE RECEPTOR PATHWAY OVERCOMES THERAPEUTIC RESISTANCE TO PD-1 BLOCKADE IN MALIGNANT GLIOMA (2019) (0)
- Automated Change Analysis of Registered Angiogenic Vasculature Images from In Vivo Multiphoton Time Series Images (2003) (0)
- Anti-VEGF therapy improves EGFR-vIII-CAR-T cell delivery and efficacy in syngeneic glioblastoma models in mice (2022) (0)
- Efficacy, Safety, and Potential Biomarkers of Sunitinib Monotherapy in Advanced Hepatocellular Carcinoma: A Phase II Study (2009) (0)
- Addition of losartan to FOLFIRINOX and chemoradiation reduces immunosuppression-associated genes, Tregs and FOXP3+ cancer cells in locally advanced pancreatic cancer. (2023) (0)
- Conventional and High-Speed Intravital Multiphoton Laser Scanning Microscopy of Microvasculature, Lymphatics, and Leukocyte-Endothelial Interactions (2002) (0)
- Abstract B03: Formation of lymph node metastases is not angiogenesis dependent (2016) (0)
- Apoptosis induction in mammary tumors in mice improves the intratumoral distribution and efficacy of oncolytic viral therapy (2007) (0)
- Abstract B19: Anti-VEGF treatment normalizes tuberculosis granuloma vasculature and improves small molecule delivery (2015) (0)
- Abstract A18: Angiotensin receptor blockers normalize the pancreatic ductal adenocarcinoma stroma by reprogramming carcinoma-associated fibroblasts (2019) (0)
- Abstract LB-348: Evolution of physical forces in the tumor microenvironment and implications for therapeutic resistance. (2013) (0)
- Using MR Spectroscopy to Track Metabolic Changes in Glioblastoma after One Dose of Cediranib (2009) (0)
- Wrapping and Tapping Anastomosis between Engrafted Endothelial Networks and Host Vasculature (2010) (0)
- 76. New Strategy To Improve Imaging and Retargeting of HSV-1 Vectors (2005) (0)
- 52. BrMPANEL: A PUBLIC RESOURCE OF ORGANOTROPIC CELL LINES (2020) (0)
- S10 02 MA – INTERSTITIAL HYPERTENSION IN TUMORS: ETIOLOGY AND THERAPEUTIC IMPLICATIONS (1991) (0)
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- Abstract A115: Use of angiotensin system inhibitors is associated with immune activation and longer survival in pancreatic ductal adenocarcinoma patients (2019) (0)
- Abstract B39: Modulation of cancer immunotherapy by the microbiome: Insights from computational analyses of preclinical studies (2022) (0)
- Is Serial MR Spectroscopy Revealing an Anti-tumor Effect of Cediranib in Human Glioblastoma ? (2008) (0)
- Abstract SY33-01: Improving immunotherapy of cancer by normalizing tumor vessels (2019) (0)
- INTERSTITIAL HYPERTENSION IN EXPERIMENTAL AND HUMAN TUMORS: ETIOLOGY AND THERAPEUTIC IMPLICATIONS (1992) (0)
- Mathematical Modeling of Herpes SimplexVirus Distribution in SolidTumors : Implications for Cancer (2009) (0)
- Tumor Microcirculation: Role in Drug and Nutrient Delivery (1997) (0)
- Direct Evidence That Increase in Tumor-Associated Macrophages (TAMs) after Antiangiogenic Therapy Is Associated with Poor Survival in Recurrent Glioblastoma (GBM) Patients (S35.001) (2013) (0)
- Abstract 2343: Targeting EPHB2/ABL1 restores anti-tumor immunity in a preclinical model of ependymoma (2023) (0)
- Advances in Brief Differential Transplantability of Tumor-Associated Stromal Cells (2004) (0)
- Abstract PR07: Reprogramming the tumor microenvironment with losartan to enhance immunotherapy of ovarian cancer (2020) (0)
- Abstract PO-097: Addition of losartan to FOLFIRINOX and chemoradiation reduces the expression of pro-invasive and immunosuppressive genes in locally-advanced pancreatic cancer (2021) (0)
- wrapping-and-tapping anastomosis Engineered blood vessel networks connect to host vasculature via (2013) (0)
- Reply to S.J. Faivre et al (2009) (0)
- CTIM-32. PHASE II AND BIOMARKER STUDY OF PEMBROLIZUMAB OR PEMBROLIZUMAB PLUS BEVACIZUMAB FOR RECURRENT GLIOBLASTOMA PATIENTS (2020) (0)
- BSCI-09. MECHANISMS OF ENHANCED DRUG DELIVERY IN BRAIN METASTASES WITH FOCUSED ULTRASOUND-INDUCED BLOOD-TUMOR BARRIER DISRUPTION (2019) (0)
- Abstract IA17: Targeting placental growth factor/ neuropilin-1 pathway inhibits growth and spread of medulloblastoma (2014) (0)
- Impact of concurrent ACE inhibitors and ARBs on outcomes with immune-checkpoint inhibitors (ICIs) for patients (pts) with metastatic renal cell carcinoma (mRCC). (2021) (0)
- Critical issues in tumor microcirculation, angiogenesis and metastasis: Biological significance and clinical relevance (2004) (0)
- Solid stress in brain tumours causes neuronal loss and neurological dysfunction and can be reversed by lithium (2019) (0)
- Abstract B12: Adding angiotensin-system inhibitors to anti-angiogenic therapy reduces vasogenic edema in newly diagnosed glioblastomas but not in recurrent disease (2017) (0)
- TAMI-64. PHYSICAL STRESSES IN BRAIN TUMORS (2020) (0)
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- Abstract PO-031: MetMap: A map of metastatic potential of human cancer cell lines (2020) (0)
- Nonlinear microscopy of living tumors and their treatment (2006) (0)
- Abstract A48: Ado-trastuzumab emtansine (T-DM1) controls tumor progression of established HER2-positive breast cancer brain metastases in mice (2016) (0)
- TAMI-05. FATTY ACID SYNTHESIS IS REQUIRED FOR HER2+ BREAST CANCER BRAIN METASTASIS (2021) (0)
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- Publisher Correction: Probing tumor microenvironment in patients with newly diagnosed glioblastoma during chemoradiation and adjuvant temozolomide with functional MRI (2019) (0)
- 1241 IL-1 blockade prevents cardiac toxicity and improves immunotherapy efficacy in mouse models of pancreatic cancer (2022) (0)
- long-lasting functional vasculature derived mesenchymal stem cells facilitate engineering of − Bone marrow (2008) (0)
- Abstract 713: Three-dimensionalin vivoblood flow mapping in tumors using optical frequency domain imaging. (2013) (0)
- Micelle-Encapsulated Quantum Dot-Porphyrin Assemblies as (2015) (0)
- Abstract 715: TGF-beta blockade improves the distribution and efficacy of chemotherapeutic agents in breast carcinoma (2011) (0)
- Abstract B41: The angiotensin receptor blocker telmisartan inhibits the growth of pancreatic ductal adenocarcinoma and improves survival (2016) (0)
- Comment on : Intratumoral lymphatics are essential for the metastatic spread and prognosis in squamous cell carcinoma of the head and neck. Authors' reply (2003) (0)
- Wrapping‐and‐tapping anastomosis connects implanted endothelial networks to host vasculature (2011) (0)
- Differential changes in tissue biomarkers after bevacizumab (BEV) alone in a neoadjuvant study of BEV and chemotherapy in ER+ breast cancer (BC) versus triple-negative breast cancer (TNBC) patients (pts). (2013) (0)
- Towards Optimal Design of Cancer Nanomedicines: Multi-stage Nanoparticles for the Treatment of Solid Tumors (2015) (0)
- Identification of ArterioVenous Shunts by Vessel Architectural Imaging Reveals Mechanisms of Vascular Normalization during Anti-Angiogenic Therapy (2013) (0)
- Meeting announcements (2005) (0)
- Abstract 5712: Nutrient scarcity confers breast cancer brain metastasis sensitivity to serine synthesis pathway inhibition (2020) (0)
- Measurement of pO2 and pH in Living Breast Tumor Models with Three-Dimensional Resolution by Multiphoton Microscopy during Combined Therapy with Herceptin (2007) (0)
- Abstract NG10: A metastasis map of human cancer cell lines (2021) (0)
- DDRE-22. TARGETING SERINE SYNTHESIS IN BRAIN METASTASIS (2021) (0)
- Inhibition of tumor growth by solid stress (1995) (0)
- Publisher Correction: Engineering and physical sciences in oncology: challenges and opportunities (2018) (0)
- Compact high-quality CdS – CdS c re – shell nanocrystals with narrow emission lin widths and suppressed blinking SUPPLEMENTARY INFORMATION (2012) (0)
- Impact of angiotensin blockade on response to PD1/L1 inhibitors for patients with metastatic urothelial carcinoma (mUC). (2021) (0)
- Abstract LB-267: Role of VEGFR-1 signaling in obesity-induced tumor progression (2015) (0)
- Inhibition of CXCR4 Enhances the Efficacy of Radiotherapy in Metastatic Prostate Cancer Models (2023) (0)
- Abstract IA01: Reengineering the tumor microenvironment to improve cancer treatment: Bench to bedside (2017) (0)
- Abstract P061: Dendritic cell paucity in mismatch repair-proficient colorectal cancer liver metastases limits the efficacy of immune checkpoint blockade (2022) (0)
- Phenotypic and functional characterization of proangiogenic monocytes (2008) (0)
- DDRE-07. FATTY ACID SYNTHESIS IS REQUIRED FOR BREAST CANCER BRAIN METASTASIS (2021) (0)
- Abstract B06: The angiotensin receptor blocker and partial PPARγ agonist telmisartan inhibits the growth of pancreatic ductal adenocarcinoma (2019) (0)
- Abstract 10187: Renin-Angiotensin-Aldosterone System Inhibitors and Overall Survival in Cancer Patients Treated with Immune Checkpoint Inhibitors (2021) (0)
- Combining losartan with radiotherapy increases tumor control and inhibits lung metastases from a HER2/neu-positive orthotopic breast cancer model (2021) (0)
- A semi-empirical model for cell kill kinetics during hyperthermia (1979) (0)
- Diffusion in Tumors and Normal Tissues (2011) (0)
- Critical issues in tumor microcirculation, angiogenesis and metastasis: biological significance and clinical relevance (2004) (0)
- Targeted Therapy in Rectal Cancer August (2017) (0)
- Cyclodextrin Polyrotaxanes: Drug and Nucleic Acid Delivery (2015) (0)
- HERMAN D. SUIT, MD, DPhil1929–2022A Giant of Modern Radiation Oncology (2022) (0)
- Vessel co-option in glioblastoma: emerging insights and opportunities (2019) (0)
- Photoacoustic Microscopy and Computed Tomography : From Bench to Bedside Lihong (2014) (0)
- F132. Leukocyte-endothelial interaction in tumors: Effects of TNFα, transplantation site and host (1995) (0)
- Irradiation of a primary tumor enhances inhibition of angiogenesis induced at a secondary site (1998) (0)
- Abstract LB-057: Hypoxia regulation of antigen presentation machinery expression in breast cancer (2018) (0)
- Reprogramming Intrahepatic Cholangiocarcinoma Immune Microenvironment by Chemotherapy and CTLA-4 Blockade Enhances Anti-PD1 Therapy (2023) (0)
- Advances in Brief Irradiation of a Primary Tumor , Unlike Surgical Removal , Enhances Angiogenesis Suppression at a Distal Site : Potential Role of Host-Tumor Interaction 1 (2000) (0)
- Abstract 3925: Optical coherence tomography imaging in cancer research. (2013) (0)
- Cognitive Activities Help Delay Dementia in 60 Plus Population (2020) (0)
- Critical issues in Tumor microcirculation, Angiogenesis and Metastasis: Biological significance and clinical relevance (2004) (0)
- Revisiting Antiangiogenic Multikinase Inhibitors in the Era of Immune Checkpoint Blockade: The Case of Sorafenib. (2022) (0)
- IFNA pathway drives the more aggressive phenotype of KRASG12D-mutant pancreatic ductal adenocarcinomas via IFNAR1/STAT3 activation (2022) (0)
- Abstract 4195: Targeting the immune microenvironment to improve colorectal cancer anti-angiogenic therapy (2016) (0)
- 67 Angiogenesis and tumour pathophysiology (2003) (0)
- Neuropilin-1 (Nrp-1) as a prognostic biomarker and potential drug target for pediatric medulloblastoma. (2013) (0)
- MR Spectroscopy as a Biomarker to Predict the Responses of Glioblastoma to an Anti-angiogenic Treatment (2010) (0)
- Modifications of blood flow in w 256 carcinoma by hyper glycemia and hyper volemia a thermal probe method (1981) (0)
- Course announcement (1972) (0)
- 45. Paclitaxel-TRAIL Enhances the Distribution of Oncolytic Herpes Simplex Virus-1 in a Human Mammary Carcinoma Xenograft (2006) (0)
- Abstract B89: Dual PD-1 and VEGFR-2 blockade induces vascular normalization and enhances antitumor immune responses in hepatocellular carcinoma (2020) (0)
- OS12.4 In vivo dynamics and targeting of vessel co-option in glioma (2019) (0)
- New Directions in Anti-Angiogenic Therapy for Glioblastoma (2017) (0)
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What Schools Are Affiliated With Rakesh Jain?
Rakesh Jain is affiliated with the following schools:
- University of Cambridge
- Harvard University
- Sojo University
- University of California, Berkeley
- University of Delaware
- University of California, San Diego
- University of California, San Francisco
- Columbia University
- University of Cyprus
- Massachusetts General Hospital
- Duke University
- University of Helsinki
- Yale University
- University College London
- IIT Kanpur
- Carnegie Mellon University
- Massachusetts Institute of Technology
- Stanford University
- Purdue University
- Johns Hopkins University