Ralf Weiskirchen
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Computer Science
Ralf Weiskirchen's Degrees
- PhD Computer Science University of Cologne
- Masters Computer Science University of Bonn
- Bachelors Computer Science University of Bonn
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(Suggest an Edit or Addition)Ralf Weiskirchen's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Roles of TGF-beta in hepatic fibrosis. (2002) (846)
- Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 (2021) (811)
- Modern pathogenetic concepts of liver fibrosis suggest stellate cells and TGF-β as major players and therapeutic targets (2006) (724)
- Hepatic recruitment of the inflammatory Gr1+ monocyte subset upon liver injury promotes hepatic fibrosis (2009) (690)
- Ito cells are liver-resident antigen-presenting cells for activating T cell responses. (2007) (403)
- Therapeutic inhibition of inflammatory monocyte recruitment reduces steatohepatitis and liver fibrosis (2018) (316)
- Functional Contribution of Elevated Circulating and Hepatic Non-Classical CD14+CD16+ Monocytes to Inflammation and Human Liver Fibrosis (2010) (301)
- Experimental liver fibrosis research: update on animal models, legal issues and translational aspects (2013) (293)
- Organ and tissue fibrosis: Molecular signals, cellular mechanisms and translational implications. (2019) (282)
- Complement factor 5 is a quantitative trait gene that modifies liver fibrogenesis in mice and humans (2005) (262)
- Bile Duct Ligation in Mice: Induction of Inflammatory Liver Injury and Fibrosis by Obstructive Cholestasis (2015) (244)
- TAK1 suppresses a NEMO-dependent but NF-kappaB-independent pathway to liver cancer. (2010) (215)
- Antagonism of the chemokine Ccl5 ameliorates experimental liver fibrosis in mice. (2010) (215)
- Cellular and molecular functions of hepatic stellate cells in inflammatory responses and liver immunology. (2014) (214)
- The carbon tetrachloride model in mice (2015) (213)
- Biomarkers of liver fibrosis: clinical translation of molecular pathogenesis or based on liver-dependent malfunction tests. (2007) (210)
- Resveratrol: How Much Wine Do You Have to Drink to Stay Healthy? (2016) (189)
- Pro-fibrogenic potential of PDGF-D in liver fibrosis. (2007) (180)
- Diethylnitrosamine (DEN)-induced carcinogenic liver injury in mice (2015) (172)
- Update on hepatic stellate cells: pathogenic role in liver fibrosis and novel isolation techniques (2012) (167)
- The concanavalin A model of acute hepatitis in mice (2015) (164)
- Isolation and culture of hepatic stellate cells. (2005) (155)
- Up‐regulated expression of the receptor for advanced glycation end products in cultured rat hepatic stellate cells during transdifferentiation to myofibroblasts (2001) (147)
- Antifibrotic effects of CXCL9 and its receptor CXCR3 in livers of mice and humans. (2009) (147)
- Dominant-negative soluble PDGF-β receptor inhibits hepatic stellate cell activation and attenuates liver fibrosis (2004) (143)
- Differential effects of TGF-beta on connective tissue growth factor (CTGF/CCN2) expression in hepatic stellate cells and hepatocytes. (2007) (143)
- CXC chemokine ligand 4 (Cxcl4) is a platelet‐derived mediator of experimental liver fibrosis (2010) (143)
- Evolving concepts of liver fibrogenesis provide new diagnostic and therapeutic options (2007) (142)
- Activation of hepatic stellate cells is associated with cytokine expression in thioacetamide-induced hepatic fibrosis in mice (2008) (142)
- Inhibition of hepatic fibrogenesis by matrix metalloproteinase‐9 mutants in mice (2006) (140)
- Liver Fibrosis: From Pathogenesis to Novel Therapies (2016) (127)
- NLRP3 inflammasome expression is driven by NF-κB in cultured hepatocytes. (2015) (125)
- Fructose: A Dietary Sugar in Crosstalk with Microbiota Contributing to the Development and Progression of Non-Alcoholic Liver Disease (2017) (123)
- Role of nanotechnology behind the success of mRNA vaccines for COVID-19 (2021) (122)
- The PDGF system and its antagonists in liver fibrosis. (2016) (121)
- Standard Operating Procedures in Experimental Liver Research: Thioacetamide model in mice and rats (2015) (118)
- The Cysteine-rich Protein Family of Highly Related LIM Domain Proteins * (1995) (116)
- Pharmacological application of caffeine inhibits TGF-beta-stimulated connective tissue growth factor expression in hepatocytes via PPARgamma and SMAD2/3-dependent pathways. (2008) (115)
- miR-133a mediates TGF-β-dependent derepression of collagen synthesis in hepatic stellate cells during liver fibrosis. (2013) (115)
- Chemokine Cxcl9 attenuates liver fibrosis‐associated angiogenesis in mice (2012) (114)
- Induction of lipocalin‐2 expression in acute and chronic experimental liver injury moderated by pro‐inflammatory cytokines interleukin‐1β through nuclear factor‐κB activation (2011) (114)
- Disturbed zinc homeostasis in diabetic patients by in vitro and in vivo analysis of insulinomimetic activity of zinc. (2012) (114)
- Expression analysis of inflammasomes in experimental models of inflammatory and fibrotic liver disease (2012) (113)
- Therapeutic Targeting of Hepatic Macrophages for the Treatment of Liver Diseases (2019) (112)
- Single Cell RNA Sequencing Identifies Subsets of Hepatic Stellate Cells and Myofibroblasts in Liver Fibrosis (2019) (111)
- Protective effects of lipocalin-2 (LCN2) in acute liver injury suggest a novel function in liver homeostasis. (2013) (106)
- Endoglin Differentially Modulates Antagonistic Transforming Growth Factor-β1 and BMP-7 Signaling* (2007) (106)
- The CRP/MLP/TLP family of LIM domain proteins: Acting by connecting (2003) (99)
- The anti-fibrotic effects of CCN1/CYR61 in primary portal myofibroblasts are mediated through induction of reactive oxygen species resulting in cellular senescence, apoptosis and attenuated TGF-β signaling. (2014) (98)
- Lipopolysaccharide-induced inflammatory liver injury in mice (2015) (97)
- Platelet-derived growth factor isoform expression in carbon tetrachloride-induced chronic liver injury (2008) (97)
- Immortal hepatic stellate cell lines: useful tools to study hepatic stellate cell biology and function? (2007) (94)
- Adenoviral expression of a transforming growth factor-β1 antisense mRNA is effective in preventing liver fibrosis in bile-duct ligated rats (2003) (94)
- Biomarkers of hepatic fibrosis, fibrogenesis and genetic pre-disposition pending between fiction and reality (2007) (93)
- Fetuin-B, a liver-derived plasma protein is essential for fertilization. (2013) (92)
- Antisense strategy against PDGF B-chain proves effective in preventing experimental liver fibrogenesis. (2004) (90)
- Changing the pathogenetic roadmap of liver fibrosis? Where did it start; where will it go? (2008) (84)
- Current Status in Testing for Nonalcoholic Fatty Liver Disease (NAFLD) and Nonalcoholic Steatohepatitis (NASH) (2019) (83)
- A functional variation in CHI3L1 is associated with severity of liver fibrosis and YKL-40 serum levels in chronic hepatitis C infection. (2009) (82)
- Lipocalin 2 (LCN2) Expression in Hepatic Malfunction and Therapy (2016) (82)
- BMP-7 as antagonist of organ fibrosis. (2009) (81)
- Systemic antigen cross‐presented by liver sinusoidal endothelial cells induces liver‐specific CD8 T‐cell retention and tolerization (2009) (81)
- Transforming growth factor-beta gene polymorphisms in sarcoidosis patients with and without fibrosis. (2006) (80)
- Pharmacological Intervention in Hepatic Stellate Cell Activation and Hepatic Fibrosis (2016) (78)
- Transforming growth factor-β1 gene polymorphisms are associated with progression of liver fibrosis in Caucasians with chronic hepatitis C infection (2005) (77)
- Hepatoprotective and Anti-fibrotic Agents: It's Time to Take the Next Step (2016) (76)
- SLC39A14 deficiency alters manganese homeostasis and excretion resulting in brain manganese accumulation and motor deficits in mice (2018) (76)
- From inflammation to fibrosis (2010) (75)
- Immunomodulatory effects of transforming growth factor-β in the liver. (2014) (75)
- Recent advances in understanding liver fibrosis: bridging basic science and individualized treatment concepts (2018) (73)
- A novel function for Myc: inhibition of C/EBP-dependent gene activation. (1996) (71)
- LIM-domain protein cysteine- and glycine-rich protein 2 (CRP2) is a novel marker of hepatic stellate cells and binding partner of the protein inhibitor of activated STAT1. (2001) (69)
- Serum proteomic profiling in patients with bladder cancer. (2009) (68)
- The fractalkine receptor CX3CR1 is involved in liver fibrosis due to chronic hepatitis C infection. (2008) (68)
- Performance of the two new fully automated anti-Müllerian hormone immunoassays compared with the clinical standard assay. (2015) (67)
- Adenoviral delivery of an antisense RNA complementary to the 3' coding sequence of transforming growth factor-beta1 inhibits fibrogenic activities of hepatic stellate cells. (2002) (65)
- Novel Bioimaging Techniques of Metals by Laser Ablation Inductively Coupled Plasma Mass Spectrometry for Diagnosis Of Fibrotic and Cirrhotic Liver Disorders (2013) (65)
- Relevance of Serum Leptin and Leptin-Receptor Concentrations in Critically Ill Patients (2010) (64)
- Common heterozygous hemochromatosis gene mutations are risk factors for inflammation and fibrosis in chronic hepatitis C (2004) (63)
- Aberrant cell cycle progression and endoreplication in regenerating livers of mice that lack a single E-type cyclin. (2009) (62)
- Activation of TGF-β within cultured hepatocytes and in liver injury leads to intracrine signaling with expression of connective tissue growth factor (2008) (61)
- Cyclin E1 and cyclin-dependent kinase 2 are critical for initiation, but not for progression of hepatocellular carcinoma (2018) (59)
- Interleukin‐27 displays interferon‐γ–like functions in human hepatoma cells and hepatocytes (2009) (59)
- BMP-7 counteracting TGF-beta1 activities in organ fibrosis. (2013) (59)
- Insulin resistance in liver cirrhosis is not associated with circulating retinol-binding protein 4. (2007) (59)
- An update on the recent advances in antifibrotic therapy (2018) (58)
- N-acetyl-L-cysteine suppresses TGF-beta signaling at distinct molecular steps: the biochemical and biological efficacy of a multifunctional, antifibrotic drug. (2005) (57)
- Connective tissue growth factor is a Smad2 regulated amplifier of transforming growth factor β actions in hepatocytes—But without modulating bone morphogenetic protein 7 signaling (2009) (57)
- Validation of connective tissue growth factor (CTGF/CCN2) and its gene polymorphisms as noninvasive biomarkers for the assessment of liver fibrosis (2009) (57)
- Dual CTLA-4 and PD-L1 Blockade Inhibits Tumor Growth and Liver Metastasis in a Highly Aggressive Orthotopic Mouse Model of Colon Cancer12 (2019) (56)
- Expression and functional analysis of endoglin in isolated liver cells and its involvement in fibrogenic Smad signalling. (2011) (56)
- Primary Cultures of Glomerular Parietal Epithelial Cells or Podocytes with Proven Origin (2012) (55)
- Identification of Endoglin in Rat Hepatic Stellate Cells (2005) (54)
- Induction of experimental obstructive cholestasis in mice (2015) (54)
- Elastin imaging enables noninvasive staging and treatment monitoring of kidney fibrosis (2019) (53)
- Platelet-derived growth factor (PDGF)-C neutralization reveals differential roles of PDGF receptors in liver and kidney fibrosis. (2013) (53)
- Elevated circulating soluble interleukin-2 receptor in patients with chronic liver diseases is associated with non-classical monocytes (2012) (53)
- Relevance of Autophagy in Parenchymal and Non-Parenchymal Liver Cells for Health and Disease (2019) (52)
- Proapoptotic effects of the chemokine, CXCL 10 are mediated by the noncognate receptor TLR4 in hepatocytes (2013) (51)
- Suppression in transformed avian fibroblasts of a gene (crp) encoding a cysteine-rich protein containing LIM domains. (1993) (51)
- Cellular Mechanisms of Liver Fibrosis (2021) (51)
- IκB kinaseα/β control biliary homeostasis and hepatocarcinogenesis in mice by phosphorylating the cell‐death mediator receptor‐interacting protein kinase 1 (2016) (49)
- Elevated asymmetric dimethylarginine levels predict short- and long-term mortality risk in critically ill patients. (2013) (48)
- Cyclin E1 controls proliferation of hepatic stellate cells and is essential for liver fibrogenesis in mice (2012) (47)
- The Marburg I variant (G534E) of the factor VII–activating protease determines liver fibrosis in hepatitis C infection by reduced proteolysis of platelet‐derived growth factor BB (2009) (46)
- Genetic Characteristics of the Human Hepatic Stellate Cell Line LX-2 (2013) (45)
- Solution Structure of the Carboxyl-terminal LIM Domain from Quail Cysteine-rich Protein CRP2* (1997) (44)
- Comparative evaluation of gene delivery devices in primary cultures of rat hepatic stellate cells and rat myofibroblasts (2000) (43)
- Circulating retinol binding protein 4 in critically ill patients before specific treatment: prognostic impact and correlation with organ function, metabolism and inflammation (2010) (43)
- Iron metabolism: pathophysiology and pharmacology. (2021) (43)
- Lipocalin-2 (LCN2) regulates PLIN5 expression and intracellular lipid droplet formation in the liver. (2014) (42)
- The hepatic lipidome: From basic science to clinical translation. (2020) (42)
- Glucocorticoid-loaded liposomes induce a pro-resolution phenotype in human primary macrophages to support chronic wound healing. (2018) (42)
- Changes of the hepatic proteome in murine models for toxically induced fibrogenesis and sclerosing cholangitis (2006) (41)
- The hop constituent xanthohumol exhibits hepatoprotective effects and inhibits the activation of hepatic stellate cells at different levels (2015) (41)
- Isolation and Culture of Primary Murine Hepatic Stellate Cells. (2017) (41)
- Clinical relevance and cellular source of elevated soluble urokinase plasminogen activator receptor (suPAR) in acute liver failure (2014) (40)
- Disruption of the latent transforming growth factor-β binding protein-1 gene causes alteration in facial structure and influences TGF-β bioavailability (2008) (40)
- Structure of Cysteine- and Glycine-rich Protein CRP2 (1998) (40)
- Gene therapy: Comprehensive overview and therapeutic applications. (2022) (40)
- Non-alcoholic fatty liver disease (NAFLD)/non-alcoholic steatohepatitis (NASH)-related liver fibrosis: mechanisms, treatment and prevention (2020) (40)
- Isolation of Mature (Peritoneum-Derived) Mast Cells and Immature (Bone Marrow-Derived) Mast Cell Precursors from Mice (2016) (39)
- Lipocalin‐2 (NGAL/LCN2), a “help‐me” signal in organ inflammation (2016) (38)
- Characterization of Sno expression in malignant melanoma. (2005) (38)
- Overexpression of Endoglin Modulates TGF-β1-Signalling Pathways in a Novel Immortalized Mouse Hepatic Stellate Cell Line (2013) (37)
- Analysis of antigen-presenting functionality of cultured rat hepatic stellate cells and transdifferentiated myofibroblasts. (2010) (36)
- Maternal factor V Leiden mutation is associated with HELLP syndrome in Caucasian women (2008) (36)
- The role of PDGF-D in healthy and fibrotic kidneys. (2016) (36)
- CCN1/CYR61 overexpression in hepatic stellate cells induces ER stress-related apoptosis. (2016) (36)
- Platelet-derived growth factor-D modulates extracellular matrix homeostasis and remodeling through TIMP-1 induction and attenuation of MMP-2 and MMP-9 gelatinase activities. (2015) (36)
- Lipid-induced up-regulation of human acyl-CoA synthetase 5 promotes hepatocellular apoptosis. (2010) (35)
- TNFR1 determines progression of chronic liver injury in the IKKγ/Nemo genetic model (2013) (35)
- Intracrine signalling of activin A in hepatocytes upregulates connective tissue growth factor (CTGF/CCN2) expression (2008) (35)
- Transforming growth factor beta 1 gene variants increase transcription and are associated with liver cirrhosis in Chinese. (2008) (35)
- Regulation and Prognostic Relevance of Symmetric Dimethylarginine Serum Concentrations in Critical Illness and Sepsis (2013) (34)
- Analysis of the transforming growth factor-beta1 (TGF-beta1) codon 25 gene polymorphism by LightCycler-analysis in patients with chronic hepatitis C infection. (2003) (34)
- The hepatic microenvironment essentially determines tumor cell dormancy and metastatic outgrowth of pancreatic ductal adenocarcinoma (2018) (33)
- Prevention of hepatic stellate cell activation using JQ1‐ and atorvastatin‐loaded chitosan nanoparticles as a promising approach in therapy of liver fibrosis (2019) (33)
- Proteomic tissue profiling for the improvement of grading of noninvasive papillary urothelial neoplasia. (2012) (33)
- TGF-β stimulation in human and murine cells reveals commonly affected biological processes and pathways at transcription level (2014) (32)
- Human mesenchymal stem cells towards non-alcoholic steatohepatitis in an immunodeficient mouse model. (2014) (32)
- Laser ablation inductively coupled plasma mass spectrometry imaging of metals in experimental and clinical Wilson's disease (2015) (32)
- Cloning, structural analysis, and chromosomal localization of the human CSRP2 gene encoding the LIM domain protein CRP2. (1997) (32)
- Zinc supplementation augments TGF‐β1‐dependent regulatory T cell induction (2017) (32)
- TGF-beta1 Does Not Induce Senescence of Multipotent Mesenchymal Stromal Cells and Has Similar Effects in Early and Late Passages (2013) (31)
- Milk Exosomes Prevent Intestinal Inflammation in a Genetic Mouse Model of Ulcerative Colitis: A Pilot Experiment (2020) (31)
- Schistosoma mansoni Egg–Secreted Antigens Activate Hepatocellular Carcinoma–Associated Transcription Factors c‐Jun and STAT3 in Hamster and Human Hepatocytes (2019) (30)
- The use of marine-derived bioactive compounds as potential hepatoprotective agents (2014) (30)
- Non-equivalence of anti-Müllerian hormone automated assays—clinical implications for use as a companion diagnostic for individualised gonadotrophin dosing (2017) (30)
- Inhibitory effect of soluble PDGF-beta receptor in culture-activated hepatic stellate cells. (2004) (30)
- Exosome-Derived MicroRNAs of Human Milk and Their Effects on Infant Health and Development (2021) (30)
- Development and evaluation of an open source Delphi-based software for morphometric quantification of liver fibrosis (2010) (29)
- Analysis of polymorphic TGFB1 codons 10, 25, and 263 in a German patient group with non-syndromic cleft lip, alveolus, and palate compared with healthy adults (2004) (29)
- Mammalian plasma fetuin-B is a selective inhibitor of ovastacin and meprin metalloproteinases (2019) (29)
- Interleukin-33 in the pathogenesis of liver fibrosis: alarming ILC2 and hepatic stellate cells (2016) (29)
- Disruption of the latent transforming growth factor-beta binding protein-1 gene causes alteration in facial structure and influences TGF-beta bioavailability. (2008) (29)
- Hypoxia Induces Astrocyte-Derived Lipocalin-2 in Ischemic Stroke (2019) (29)
- Reconstruction of laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) spatial distribution images in Microsoft Excel 2007 (2016) (29)
- Simultaneous monitoring of cerebral metal accumulation in an experimental model of Wilson’s disease by laser ablation inductively coupled plasma mass spectrometry (2014) (28)
- Software solutions for evaluation and visualization of laser ablation inductively coupled plasma mass spectrometry imaging (LA-ICP-MSI) data: a short overview (2019) (28)
- Structure and intramodular dynamics of the amino-terminal LIM domain from quail cysteine- and glycine-rich protein CRP2. (1998) (28)
- Adenoviral-mediated transfer of p53 or retinoblastoma protein blocks cell proliferation and induces apoptosis in culture-activated hepatic stellate cells. (2003) (28)
- Factor VII activating protease (FSAP) exerts anti-inflammatory and anti-fibrotic effects in liver fibrosis in mice and men. (2013) (28)
- Bioimaging of copper deposition in Wilson's diseases mouse liver by laser ablation inductively coupled plasma mass spectrometry imaging (LA-ICP-MSI) (2013) (27)
- Isolation and Time Lapse Microscopy of Highly Pure Hepatic Stellate Cells (2015) (27)
- Fructose and Non-Alcoholic Steatohepatitis (2021) (27)
- The miR-371∼373 Cluster Represses Colon Cancer Initiation and Metastatic Colonization by Inhibiting the TGFBR2/ID1 Signaling Axis. (2018) (27)
- PDGF-D signaling in portal myofibroblasts and hepatic stellate cells proves identical to PDGF-B via both PDGF receptor type α and β. (2015) (26)
- Transforming growth factor-beta1 gene polymorphisms are associated with progression of liver fibrosis in Caucasians with chronic hepatitis C infection. (2005) (26)
- Mouse models of metabolic liver injury (2015) (26)
- The Influence of Different Fat Sources on Steatohepatitis and Fibrosis Development in the Western Diet Mouse Model of Non-alcoholic Steatohepatitis (NASH) (2019) (26)
- Antagonism of the chemokine Ccl 5 ameliorates experimental liver fibrosis in mice (2010) (26)
- A novel, dual role of CCN3 in experimental glomerulonephritis: pro-angiogenic and antimesangioproliferative effects. (2012) (26)
- Adenoviral dominant-negative soluble PDGFRβ improves hepatic collagen, systemic hemodynamics, and portal pressure in fibrotic rats. (2012) (26)
- Circulating factor VII activating protease (FSAP) is associated with clinical outcome in acute coronary syndrome. (2012) (26)
- Suppression in transformed avian fibroblasts of a gene (CO6) encoding a membrane protein related to mammalian potassium channel regulatory subunits (1997) (25)
- CCN3/NOV small interfering RNA enhances fibrogenic gene expression in primary hepatic stellate cells and cirrhotic fat storing cell line CFSC (2012) (25)
- The expression of CSRP2 encoding the LIM domain protein CRP2 is mediated by TGF-beta in smooth muscle and hepatic stellate cells. (2006) (25)
- Mast Cells in Liver Fibrogenesis (2019) (24)
- [Pathogenesis of liver fibrosis: modulation of stellate cells by chemokines]. (2010) (24)
- Endoglin in liver fibrogenesis: Bridging basic science and clinical practice. (2014) (24)
- The cysteine- and glycine-rich LIM domain protein CRP2 specifically interacts with a novel human protein (CRP2BP). (2000) (24)
- Targeted disruption of the mouse Csrp2 gene encoding the cysteine- and glycine-rich LIM domain protein CRP2 result in subtle alteration of cardiac ultrastructure (2008) (24)
- It’s all about the spaces between cells: role of extracellular matrix in liver fibrosis (2020) (23)
- Magnetic-Assisted Treatment of Liver Fibrosis (2019) (23)
- CSRP2, TIMP‐1, and SM22α promoter fragments direct hepatic stellate cell‐specific transgene expression in vitro, but not in vivo (2004) (23)
- Experience with the first fully automated chemiluminescence immunoassay for the quantification of 1α, 25-dihydroxy-vitamin D (2015) (23)
- ITIH5 mediates epigenetic reprogramming of breast cancer cells (2017) (22)
- Mechanisms Underlying Cell Therapy in Liver Fibrosis: An Overview (2019) (22)
- Proteomic profiling in Lipocalin 2 deficient mice under normal and inflammatory conditions. (2013) (22)
- Identification of Pparγ-modulated miRNA hubs that target the fibrotic tumor microenvironment (2019) (22)
- Mammalian gamete fusion depends on the inhibition of ovastacin by fetuin-B (2014) (22)
- Interleukin-27 acts on hepatic stellate cells and induces signal transducer and activator of transcription 1-dependent responses (2010) (22)
- Dysregulated mesenchymal PDGFR‐β drives kidney fibrosis (2020) (22)
- Conditional cell transformation by doxycycline-controlled expression of the MC29 v-myc allele. (1999) (22)
- The tightrope of therapeutic suppression of active transforming growth factor-beta: high enough to fall deeply? (2003) (22)
- Sequence and expression of a glyceraldehyde-3-phosphate dehydrogenase-encoding gene from quail embryo fibroblasts. (1993) (21)
- Liver function critically determines serum retinol‐binding protein 4 (RBP4) levels in patients with chronic liver disease and cirrhosis (2008) (21)
- Altered mitochondrial and peroxisomal integrity in lipocalin-2-deficient mice with hepatic steatosis. (2017) (21)
- Comparative analysis of adenoviral transgene delivery via tail or portal vein into rat liver (2004) (21)
- Clinical features of Wilson disease. (2019) (21)
- Pathogenese der Leberfibrose: Regulation von hepatischen Sternzellen durch Chemokine (2010) (21)
- Evaluation of a novel reverse-hybridization StripAssay for typing DNA variants useful in diagnosis of adult-type hypolactasia. (2008) (21)
- Trace metal imaging in diagnostic of hepatic metal disease. (2016) (20)
- CCN proteins in normal and injured liver. (2011) (20)
- Occult celiac disease prevents penetrance of hemochromatosis. (2005) (20)
- Abrogation of both short and long forms of latent transforming growth factor-β binding protein-1 causes defective cardiovascular development and is perinatally lethal. (2015) (20)
- Endoglin in human liver disease and murine models of liver fibrosis—A protective factor against liver fibrosis (2017) (19)
- Mutational analysis and NMR spectroscopy of quail cysteine and glycine-rich protein CRP2 reveal an intrinsic segmental flexibility of LIM domains. (1999) (19)
- Identification of fibrosis-relevant proteins using DIGE (difference in gel electrophoresis) in different models of hepatic fibrosis. (2005) (19)
- Age-independent anti-Müllerian hormone (AMH) standard deviation scores to estimate ovarian function. (2017) (19)
- Adenoviral CCN3/NOV gene transfer fails to mitigate liver fibrosis in an experimental bile duct ligation model because of hepatocyte apoptosis (2012) (19)
- Perilipin 5 and Lipocalin 2 Expression in Hepatocellular Carcinoma (2019) (19)
- Analytical evaluation of the novel soluble fms-like tyrosine kinase 1 and placental growth factor assays for the diagnosis of preeclampsia. (2015) (19)
- From proteomic multimarker profiling to interesting proteins: thymosin-β4 and kininogen-1 as new potential biomarkers for inflammatory hepatic lesions (2011) (19)
- Structure of mammalian plasma fetuin-B and its mechanism of selective metallopeptidase inhibition (2019) (18)
- Visfatin Serum Levels Predict Mortality in Critically Ill Patients (2018) (18)
- Induction of cell death in activated hepatic stellate cells by targeted gene expression of the thymidine kinase/ganciclovir system. (2004) (18)
- Clinical relevance of copeptin plasma levels as a biomarker of disease severity and mortality in critically ill patients (2018) (18)
- Endoglin: An ‘Accessory’ Receptor Regulating Blood Cell Development and Inflammation (2020) (17)
- The murine latent transforming growth factor-beta binding protein (Ltbp-1) is alternatively spliced, and maps to a region syntenic to human chromosome 2p21-22. (2003) (17)
- A novel proximal -13914G>A base replacement in the vicinity of the common-13910T/C lactase gene variation results in an atypical LightCycler melting curve in testing with the MutaREAL Lactase test. (2007) (17)
- Pitfalls in LightCycler diagnosis of the single-nucleotide polymorphism 13.9 kb upstream of the lactase gene that is associated with adult-type hypolactasia. (2007) (17)
- L-Selectin/CD62L Is a Key Driver of Non-Alcoholic Steatohepatitis in Mice and Men (2020) (17)
- Intrahepatic TH17/TReg Cells in Homeostasis and Disease—It’s All About the Balance (2020) (17)
- Questioning the challenging role of epithelial‐to‐mesenchymal transition in liver injury (2011) (17)
- Hemochromatosis gene sequence deviations in German patients with porphyria cutanea tarda. (2006) (17)
- Cryopreservation of hepatic stellate cells. (2006) (16)
- Global analysis of host tissue gene expression in the invasive front of colorectal liver metastases. (2005) (16)
- ITIH5 induces a shift in TGF‐β superfamily signaling involving Endoglin and reduces risk for breast cancer metastasis and tumor death (2018) (16)
- Lipocalin-2 in Fructose-Induced Fatty Liver Disease (2017) (16)
- Recombinant fetuin-B protein maintains high fertilization rate in cumulus cell-free mouse oocytes (2017) (16)
- It's not all in the cilium, but on the road to it: genetic interaction network in polycystic kidney and liver diseases and how trafficking and quality control matter. (2012) (16)
- Biomedical applications of polysaccharide nanoparticles for chronic inflammatory disorders: Focus on rheumatoid arthritis, diabetes and organ fibrosis. (2021) (16)
- All You Can Feed: Some Comments on Production of Mouse Diets Used in Biomedical Research with Special Emphasis on Non-Alcoholic Fatty Liver Disease Research (2020) (15)
- TGF-β up-regulates serum response factor in activated hepatic stellate cells (2007) (15)
- Variable expression of cystatin C in cultured trans-differentiating rat hepatic stellate cells. (2006) (15)
- Human intestinal acyl-CoA synthetase 5 is sensitive to the inhibitor triacsin C. (2011) (15)
- [Liver fibrosis - pathogenesis and novel therapeutic approaches]. (2010) (15)
- Bispheric Coordinative Structuring in a Zinc Finger Protein: NMR Analysis of a Point Mutant of the Carboxy-Terminal LIM Domain of Quail Cysteine- and Glycine-Rich Protein CRP2 (1998) (15)
- N-Glycosylation of Lipocalin 2 Is Not Required for Secretion or Exosome Targeting (2018) (15)
- Altered factor VII activating protease expression in murine hepatic fibrosis and its influence on hepatic stellate cells (2009) (15)
- Targeting Activated Hepatic Stellate Cells Using Collagen-Binding Chitosan Nanoparticles for siRNA Delivery to Fibrotic Livers (2020) (14)
- Non-synonymous gene polymorphisms in the secretory signal peptide of human TGF-beta1 affect cellular synthesis but not secretion of TGF-beta1. (2009) (14)
- Elevated CTRP1 Plasma Concentration Is Associated with Sepsis and Pre-Existing Type 2 Diabetes Mellitus in Critically Ill Patients (2019) (14)
- Liver fibrosis: Which mechanisms matter? (2016) (14)
- Liver parenchymal cells lacking Lipocalin 2 (LCN2) are prone to endoplasmic reticulum stress and unfolded protein response. (2019) (14)
- Bone Morphogenetic Protein-8B Expression is Induced in Steatotic Hepatocytes and Promotes Hepatic Steatosis and Inflammation In Vitro (2019) (14)
- Endoglin Trafficking/Exosomal Targeting in Liver Cells Depends on N-Glycosylation (2019) (14)
- High mobility group box 1 as a biomarker in critically ill patients (2018) (14)
- Brain copper storage after genetic long-term correction in a mouse model of Wilson disease (2018) (14)
- Atypical melting curve resulting from genetic variation in the 3' untranslated region at position 20218 in the prothrombin gene analyzed with the LightCycler factor II (prothrombin) G20210A assay. (2005) (13)
- BMP-7/TGF-β1 signalling in myoblasts: components involved in signalling and BMP-7-dependent blockage of TGF-β-mediated CTGF expression. (2012) (13)
- Deletion of Perilipin 5 Protects against Hepatic Injury in Nonalcoholic Fatty Liver Disease via Missing Inflammasome Activation (2020) (13)
- Molecular response of liver sinusoidal endothelial cells on hydrogels. (2015) (13)
- Exercise-Induced Release of Pharmacologically Active Substances and Their Relevance for Therapy of Hepatic Injury (2016) (13)
- High Prevalence of Sticky Platelet Syndrome in Patients with Infertility and Pregnancy Loss (2019) (12)
- Fatty acid binding receptors in intestinal physiology and pathophysiology. (2010) (12)
- Recombinant Expression, Purification, and Functional Characterisation of Connective Tissue Growth Factor and Nephroblastoma-Overexpressed Protein (2010) (12)
- Elevated MR-proANP plasma concentrations are associated with sepsis and predict mortality in critically ill patients (2019) (12)
- Lipocalin 2 in the pathogenesis of fatty liver disease and nonalcoholic steatohepatitis (2015) (12)
- Portal myofibroblasts are sensitive to CCN-mediated endoplasmic reticulum stress-related apoptosis with potential to attenuate biliary fibrogenesis. (2018) (12)
- Roles of CCR2 and CCR5 for Hepatic Macrophage Polarization in Mice With Liver Parenchymal Cell-Specific NEMO Deletion (2020) (12)
- An unusual melting curve profile in LightCycler multiplex genotyping of the hemochromatosis H63D/C282Y gene mutations. (2001) (12)
- Depletion of Lipocalin 2 (LCN2) in Mice Leads to Dysbiosis and Persistent Colonization with Segmented Filamentous Bacteria (2021) (11)
- Disruption of intermolecular disulfide bonds in PDGF-BB dimers by N-acetyl-L-cysteine does not prevent PDGF signaling in cultured hepatic stellate cells. (2005) (11)
- New Aspects of Kidney Fibrosis–From Mechanisms of Injury to Modulation of Disease (2022) (11)
- The Impact of a Nitric Oxide Synthase Inhibitor (L-NAME) on Ischemia–Reperfusion Injury of Cholestatic Livers by Pringle Maneuver and Liver Resection after Bile Duct Ligation in Rats (2019) (11)
- Adenoviral CCN gene transfers induce in vitro and in vivo endoplasmic reticulum stress and unfolded protein response. (2016) (11)
- Severity of Coronavirus Disease 2019 (COVID-19): Does Surfactant Matter? (2020) (11)
- The nucleic acid binding protein YB-1-controlled expression of CXCL-1 modulates kidney damage in liver fibrosis. (2019) (11)
- Factor seven ativating potease (FSAP) levels during normal pregnancy and in women using oral contraceptives. (2010) (11)
- Intratumor heterogeneity, variability and plasticity: questioning the current concepts in classification and treatment of hepatocellular carcinoma. (2016) (11)
- Has GnRH a direct role in AMH regulation? (2019) (11)
- TNF-α controls Lipocalin-2 expression in PC-3 prostate cancer cells. (2020) (11)
- What Does the “AKT” Stand for in the Name “AKT Kinase”? Some Historical Comments (2020) (10)
- Therapeutic strategies in Wilson disease: pathophysiology and mode of action (2020) (10)
- Pharmacological application of caffeine inhibits TGF-b-stimulated connective tissue growth factor expression in hepatocytes via PPAR c and SMAD 2 / 3-dependent pathways q (2008) (10)
- Severity assessment in mice subjected to carbon tetrachloride (2020) (10)
- Macrophage migration inhibitory factor exerts pro-proliferative and anti-apoptotic effects via CD74 in murine hepatocellular carcinoma (2020) (10)
- Quantification of liver iron overload disease with laser ablation inductively coupled plasma mass spectrometry (2018) (10)
- Rapid genotyping of the G534E polymorphism (Marburg I) of the gene encoding the factor VII-activating protease (FSAP) by LightCycler PCR. (2007) (10)
- Age-specific reference values improve the diagnostic performance of AMH in polycystic ovary syndrome (2020) (10)
- The CSRP2BP histone acetyltransferase drives smooth muscle gene expression (2016) (10)
- Visualization of the therapeutic efficacy of a gene correction approach in Wilson's disease by laser-ablation inductively coupled mass spectrometry. (2018) (10)
- Apoptosis and Pharmacological Therapies for Targeting Thereof for Cancer Therapeutics (2022) (10)
- Determination of copper poisoning in Wilson's disease using laser ablation inductively coupled plasma mass spectrometry. (2019) (9)
- Advances in the clinical use of collagen as biomarker of liver fibrosis (2020) (9)
- Emerging Role of PD-1/PD-L1 Inhibitors in Chronic Liver Diseases (2021) (9)
- Deficiency in four and one half LIM domain protein 2 (FHL2) aggravates liver fibrosis in mice (2013) (9)
- Global analysis of host tissue gene expression in the invasive front of colorectal liver metastases (2006) (9)
- High Circulating Caspase-Cleaved Keratin 18 Fragments (M30) Indicate Short-Term Mortality in Critically Ill Patients (2018) (9)
- Usage of Mitogen-Activated Protein Kinase Small Molecule Inhibitors: More Than Just Inhibition! (2018) (9)
- Expression of the megalin C-terminal fragment by macrophages during liver fibrogenesis in mice. (2011) (9)
- Special Issue on “Cellular and Molecular Mechanisms Underlying the Pathogenesis of Hepatic Fibrosis” (2020) (9)
- Understanding the Role of Perilipin 5 in Non-Alcoholic Fatty Liver Disease and Its Role in Hepatocellular Carcinoma: A Review of Novel Insights (2021) (9)
- Technical and diagnostic performance of a new fully automated immunoassay for the determination of intact fibroblast growth factor 23 (FGF23) (2018) (9)
- Immune surveillance of liver cancer in non-alcoholic fatty liver disease: excess lipids cause CD4 T-cells loss and promote hepatocellular carcinoma development. (2016) (9)
- Association of Serum Calprotectin Concentrations with Mortality in Critically Ill and Septic Patients (2020) (9)
- In Vitro Compression Model for Orthodontic Tooth Movement Modulates Human Periodontal Ligament Fibroblast Proliferation, Apoptosis and Cell Cycle (2021) (9)
- A Scoping Review on Lipocalin-2 and Its Role in Non-Alcoholic Steatohepatitis and Hepatocellular Carcinoma (2021) (9)
- Phosphatidylcholine Passes by Paracellular Transport to the Apical Side of the Polarized Biliary Tumor Cell Line Mz-ChA-1 (2019) (8)
- Decreased CTRP3 Plasma Concentrations Are Associated with Sepsis and Predict Mortality in Critically Ill Patients (2019) (8)
- Single‐cell omics: Overview, analysis, and application in biomedical science (2021) (8)
- LightCycler-analysis of the Transforming Growth Factor-beta1 Codon 25 Gene Polymorphism in German Patients with Chronic Hepatitis C Infection (2004) (8)
- The Role of Radiologic Modalities in Diagnosing Nonalcoholic Steatohepatitis (NASH) and Fibrosis (2018) (8)
- PTGS1 compound heterozygosity impairs gene expression and platelet aggregation and is associated with severe bleeding complications (2013) (8)
- Liver Fibrosis—From Mechanisms of Injury to Modulation of Disease (2022) (8)
- Unexpected Pro-Fibrotic Effect of MIF in Non-Alcoholic Steatohepatitis Is Linked to a Shift in NKT Cell Populations (2021) (8)
- False-negative results in the immunoassay analysis of drugs of abuse: can adulterants be detected by sample check test? (2018) (8)
- Bone morphogenetic protein‐7 in focus: A member of the transforming growth factor‐β superfamily is implicated in the maintenance of liver health (2007) (8)
- Relevance of serum sclerostin concentrations in critically ill patients (2017) (8)
- Recent Advances in Practical Methods for Liver Cell Biology: A Short Overview (2020) (8)
- Perilipin 5 Ameliorates Hepatic Stellate Cell Activation via SMAD2/3 and SNAIL Signaling Pathways and Suppresses STAT3 Activation (2021) (8)
- Factor VII activating protease (FSAP): A novel protective factor in liver fibrosis (2014) (7)
- Identification of paraxanthine as the most potent caffeine-derived inhibitor of connective tissue growth factor expression in liver parenchymal cells (2009) (7)
- Differential regulation of Lipocalin 2 (LCN2) in doxorubicin-resistant 4T1 triple negative breast cancer cells. (2020) (7)
- Inflammatory Responses of Astrocytes Are Independent from Lipocalin 2 (2020) (7)
- The genes that underlie fatty liver disease: The harvest has begun (2009) (7)
- MAKERGAUL: an innovative MAK2-based model and software for real-time PCR quantification. (2014) (7)
- The potential pathophysiological role of altered lipid metabolism and electronegative low-density lipoprotein (LDL) in non-alcoholic fatty liver disease and cardiovascular diseases. (2021) (6)
- Short-Term Western Diet Aggravates Non-Alcoholic Fatty Liver Disease (NAFLD) With Portal Hypertension in TGR(mREN2)27 Rats (2020) (6)
- Flow Cytometry: A Blessing and a Curse (2021) (6)
- Cross-method comparison of serum androstenedione measurement with respect to the validation of a new fully automated chemiluminescence immunoassay. (2018) (6)
- Genetic and Molecular Characterization of the Immortalized Murine Hepatic Stellate Cell Line GRX (2022) (6)
- Delayed-Release Phosphatidylcholine Is Effective for Treatment of Ulcerative Colitis: A Meta-Analysis (2021) (6)
- TGF-beta up-regulates serum response factor in activated hepatic stellate cells. (2007) (6)
- Low Myostatin Serum Levels Are Associated with Poor Outcome in Critically Ill Patients (2020) (6)
- Platelet Factor 4 Attenuates Experimental Acute Liver Injury in Mice (2019) (6)
- Chronic Carbon Tetrachloride Applications Induced Hepatocyte Apoptosis in Lipocalin 2 Null Mice through Endoplasmic Reticulum Stress and Unfolded Protein Response (2020) (5)
- Genetic Characterization of Rat Hepatic Stellate Cell Line HSC-T6 for In Vitro Cell Line Authentication (2022) (5)
- Identification of platelet-derived growth factor C as a mediator of both renal fibrosis and hypertension. (2019) (5)
- The Inhibitory T Cell Receptors PD1 and 2B4 Are Differentially Regulated on CD4 and CD8 T Cells in a Mouse Model of Non-alcoholic Steatohepatitis (2019) (5)
- Reference change values of M-protein, free light chain and immunoglobulins in monoclonal gammopathy. (2019) (5)
- Accurate Measurement of Copper Overload in an Experimental Model of Wilson Disease by Laser Ablation Inductively Coupled Plasma Mass Spectrometry (2020) (5)
- Pathophysiologie der Leberfibrose (2010) (5)
- Antifibrotic Effects of Amyloid-Beta and Its Loss in Cirrhotic Liver (2020) (5)
- Combining GP73 with liver stiffness measurements: A proof‐of‐concept for non‐invasive fibrosis assessment in antiviral‐naïve HBV patients (2017) (5)
- Latent TGF-β binding protein-1 deficiency decreases female fertility. (2017) (5)
- Genetic characteristics of the human hepatic stellate cell line LX–2 (2012) (5)
- Protective effects of Lipocalin-2 (LCN2) in acute and chronic liver injury indicate a novel function in liver homeostasis (2013) (5)
- The expression and antigenicity identification of recombinant rat TGF-β1 in bacteria (2001) (5)
- COMMD1, a multi-potent intracellular protein involved in copper homeostasis, protein trafficking, inflammation, and cancer. (2021) (5)
- Mining the Age-Dependent Reference Intervals of B Vitamins from Routine Laboratory Test Results (2018) (4)
- Four-And-A-Half LIM-Domain Protein 2 (FHL2) Deficiency Aggravates Cholestatic Liver Injury (2020) (4)
- In search of early events in the development of chronic kidney disease: the emerging role for lipocalin-2/NGAL. (2011) (4)
- P0432 : NLRP3 inflammasome expression is regulated by nuclear factor-kappab(NF-κB)in cultured hepatocytes (2015) (4)
- Hepatitis-C-Diagnostik: Klinische Evaluierung der HCV-Core-Antigenbestimmung (2014) (4)
- α2-Adrenergic Receptor in Liver Fibrosis: Implications for the Adrenoblocker Mesedin (2020) (4)
- Assignment1 of CSRP1 encoding the LIM domain protein CRP1, to human chromosome 1q32 by fluorescence in situ hybridization (1999) (4)
- Pharmacological application of caffeine inhibits TGF-β-stimulated connective tissue growth factor (CTGF/CCN2) expression in hepatocytes via PPARγ and Smad2/3-dependent pathways (2008) (4)
- Tgf-β and the Smad Pathway in Liver Fibrogenesis (2005) (4)
- The Unfolded Protein Response Is a Major Driver of LCN2 Expression in BCR–ABL- and JAK2V617F-Positive MPN (2021) (4)
- Midregional Proadrenomedullin (MRproADM) Serum Levels in Critically Ill Patients Are Associated with Short-Term and Overall Mortality during a Two-Year Follow-Up (2020) (4)
- Standard Operating Procedures in Experimental Liver Research: Time to achieve uniformity (2015) (4)
- Laser Ablation Inductively Coupled Plasma Spectrometry: Metal Imaging in Experimental and Clinical Wilson Disease (2019) (4)
- Disorders of the glucose metabolism correlate with the phenotype and the severity in women with polycystic ovary syndrome (2020) (3)
- IL-13 as Target to Reduce Cholestasis and Dysbiosis in Abcb4 Knockout Mice (2020) (3)
- Rapid detection of CSRP2 mRNA in mouse, rat, and human using LightCycler-based quantitative real-time polymerase chain reaction. (2003) (3)
- Vitamin B1 interpretation: Erroneous higher levels in non-anemic populations. (2019) (3)
- Laser Ablation Inductively Coupled Plasma Mass Spectrometry in Biomedicine and Clinical Diagnosis (2018) (3)
- Glucagon-like peptide 1 and fibroblast growth factor-21 in non-alcoholic steatohepatitis: An experimental to clinical perspective. (2022) (3)
- Wilson’s Disease: An Inherited, Silent, Copper Intoxication Disease (2016) (3)
- with progression of liver fibrosis in Caucasians with chronic hepatitis C infection (2005) (3)
- Milk exosomal microRNAs: friend of foe?—a narrative review (2022) (3)
- Lipoxygenases in chronic liver diseases: current insights and future perspectives (2021) (3)
- A comprehensive overview of CRISPR/Cas 9 technology and application thereof in drug discovery (2022) (3)
- CT-based determination of excessive visceral adipose tissue is associated with an impaired survival in critically ill patients (2021) (3)
- Serum Perilipin 2 (PLIN2) Predicts Multiple Organ Dysfunction in Critically Ill Patients (2021) (3)
- Analyzing the Therapeutic Efficacy of Bis-Choline-Tetrathiomolybdate in the Atp7b−/− Copper Overload Mouse Model (2021) (3)
- Liver immunology: new perspectives. (2014) (3)
- Resveratrol: Is It Really Good for Liver Health? (2017) (3)
- Pathogenesis, Diagnostics, and Treatment of Hereditary Haemochromatosis: A 150 Year-Long Understanding of an Iron Overload Disorder (2017) (3)
- Small heterodimer partner (SHP) links hepatitis C and liver fibrosis: a small protein on the big stage (2015) (2)
- Wilson disease — the impact of hyperimmunity on disease activity: A case report (2021) (2)
- Data on Lipocalin 2 and phosphatidylinositol 3-kinase signaling in a methionine- and choline-deficient model of non-alcoholic steatohepatitis (2017) (2)
- When sleeping beauty wakes up and jumps into a cancer‐minded environment (2009) (2)
- Improved Method for Isolating Cell (2005) (2)
- Lipocalin-2 (LCN2) Deficiency Leads to Cellular Changes in Highly Metastatic Human Prostate Cancer Cell Line PC-3 (2022) (2)
- Faculty Opinions recommendation of The gut microbiota: A new potential driving force in liver cirrhosis and hepatocellular carcinoma. (2018) (2)
- The neglected biliary mucus and its phosphatidylcholine content: a putative player in pathogenesis of primary cholangitis—a narrative review article (2020) (2)
- The Bile Acid-Phospholipid Conjugate Ursodeoxycholyl-Lysophosphatidylethanolamide (UDCA-LPE) Disintegrates the Lipid Backbone of Raft Plasma Membrane Domains by the Removal of the Membrane Phospholipase A2 (2019) (2)
- The endocrine and epigenetic impact of persistent cow milk consumption on prostate carcinogenesis (2022) (2)
- Structure of mammalian plasma fetuin-B and its mechanism of selective metallopeptidase inhibition. (2019) (2)
- Faculty Opinions recommendation of The pentraxins PTX3 and SAP in innate immunity, regulation of inflammation and tissue remodelling. (2018) (2)
- Lipopolysaccharide-induced acute phase response: New views on trace metal plasticity in hepatic inflammation (2018) (2)
- Established Liver Cell Lines: Are You Sure to Have the Right Ones? (2022) (2)
- Corrigendum to “Inhibitory effect of soluble PDGF-β receptor in culture-activated hepatic stellate cells” [Biochem. Biophys. Res. Commun. 317 (2004) 451–462] (2004) (2)
- Quantification of Short Chain Fatty Acids (acetate, butyrate, propionate) in human blood with ion exclusion chromatography (2021) (2)
- Letter to the editor regarding “Dietary bovine milk miRNAs transported in extracellular vesicles are partially stable during GI digestion, are bioavailable and reach target tissues but need a minimum dose to impact on gene expression” (2022) (2)
- Assessing the severity of laparotomy and partial hepatectomy in male rats—A multimodal approach (2021) (2)
- Physalin B attenuates liver fibrosis via suppressing LAP2α‐HDAC1 mediated deacetylation of glioma‐associated oncogene 1 and hepatic stellate cell activation (2021) (2)
- Faculty Opinions recommendation of A gain-of-function mutation in the PDGFR-beta alters the kinetics of injury response in liver and skin. (2008) (2)
- Faculty Opinions recommendation of Vinculin and cellular retinol-binding protein-1 are markers for quiescent and activated hepatic stellate cells in formalin-fixed paraffin embedded human liver. (2009) (1)
- Tumor Necrosis Factor-α (TNFα) Stimulate Triple-Negative Breast Cancer Stem Cells to Promote Intratumoral Invasion and Neovasculogenesis in the Liver of a Xenograft Model (2022) (1)
- Special Issue on “Cellular and Molecular Mechanisms Underlying the Pathogenesis of Hepatic Fibrosis II” (2022) (1)
- Commentary on “Re‐regulation of hepatic stellate cell contraction and cirrhotic portal hypertension by Wnt/β‐catenin signaling via interaction with Gli1” (2020) (1)
- Faculty Opinions recommendation of The global burden of viral hepatitis from 1990 to 2013: findings from the Global Burden of Disease Study 2013. (2018) (1)
- The biotin interference within interference suppressed immunoassays (2021) (1)
- Soluble Endoglin modulates TGF-β1 mediated signaling in isolated hepatocytes (2008) (1)
- Commentary: Montelukast Prevents Mice Against Acetaminophen-Induced Liver Injury (2019) (1)
- From Mice to Humans: The Study of Obesity (2020) (1)
- The importance of soluble anti-Müllerian hormone receptor type 2 (sAMHR2) as a new serum marker in diagnosis of fertility disorders in women (2019) (1)
- Faculty Opinions recommendation of The ASK1 inhibitor selonsertib in patients with nonalcoholic steatohepatitis: A randomized, phase 2 trial. (2018) (1)
- Identification of the chemokine CXCL9 (MIG) as a genetic modifier of liver fibrosis in patients with hepatitis C (2006) (1)
- Ccn1, a molecular switch that imposes a self-limiting control on inflammation and wound healing in a multitude of organs? (2015) (1)
- 139 Complement factor 5 (C5) is a genetic determinant of liver fibrogenesis in mice and humans (2003) (1)
- Laser Ablation Inductively CoupledPlasma Mass Spectrometry inBiomedicine and Clinical Diagnosis (2015) (1)
- Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) in trace metal imaging of experimental and clinical metal disorders (2015) (1)
- Therapeutic targeting of the mitochondrial reactive oxygen species engine prevents portal hypertension and hepatic fibrogenesis (2017) (1)
- The interesting case-orphan diseases-double trouble. (2019) (1)
- Multiplex short tandem repeat profiling of immortalized hepatic stellate cell line Col-GFP HSC (2022) (1)
- Effect of cellular and microenvironmental multidrug resistance on tumor-targeted drug delivery in triple-negative breast cancer. (2023) (1)
- Faculty Opinions recommendation of Thiazolidinediones and Advanced Liver Fibrosis in Nonalcoholic Steatohepatitis: A Meta-analysis. (2018) (1)
- Soluble anti-müllerian hormone receptor type 2 (SAMHR2): A new biomarker for diagnosis of fertility disorders (2019) (1)
- Elevation of Autoantibodies to Cerebral Proteins in Hepatic Encephalopathy: Another Pathogenic Factor? (2021) (1)
- Fast progression of liver damage in lysosomal acid lipase deficiency (2017) (1)
- Faculty Opinions recommendation of Primary sclerosing cholangitis - a comprehensive review. (2018) (1)
- P0285 : Inactivation of cyclin E1 acts pro-apoptotic and anti-proliferative in primary hepatoma cells and protects from hepatocarcinogenesis in mice (2015) (1)
- Standardization and Normalization of Data from Laser Ablation Inductively Coupled Plasma Mass Spectrometry (2016) (1)
- 599 TRANSDUCTION OF ADENOVIRUS ENCODING DOMINANT-NEGATIVE SOLUBLE PDGFRβ IMPROVES SYSTEMIC HEMODYNAMICS, PORTAL PRESSURE AND HEPATIC FIBROSIS IN RATS CHRONICALLY TREATED WITH CCL4 (2011) (1)
- Latent transforming growth factor-β binding protein 1 (LTBP1) – only one representative of various related proteins involved in the development of liver fibrosis? (2005) (1)
- Manipulation of THC Hair Concentrations by Commercially Available Products (2022) (1)
- Phyllis Jean McAlpine, Ph.D, FCCMG (1999) (1)
- A Century of Progress on Wilson Disease and the Enduring Challenges of Genetics, Diagnosis, and Treatment (2023) (1)
- CCN3/NOV small interfering RNA enhances fibrogenic gene expression in primary hepatic stellate cells and cirrhotic fat storing cell line CFSC (2011) (1)
- [104] FUNCTIONAL AND GENETIC INTERACTION OF THE CHEMOKINES CCL (RANTES) AND CXCL (PF) IN CHRONIC LIVER DISEASES IN MICE AND HUMANS (2007) (1)
- Editorial: Liver Myofibroblasts (2016) (1)
- Expression of pleiotrophin and its receptors in hepatic cells and in activated hepatic stellate cells (HSCs)– Pleiotrophin in hepatic stellate cells (2004) (1)
- Narrative review of bovine milk exosomes as a potential therapeutic option for hepatic fibrosis (2021) (1)
- A yellow bullet against the drivers of hepatic fibrogenesis (2008) (1)
- Simultaneous monitoring of cerebral metal accumulation in an experimental model of Wilson’s disease by laser ablation inductively coupled plasma mass spectrometry (2014) (1)
- Rat Hepatic Stellate Cell Line CFSC-2G: Genetic Markers and Short Tandem Repeat Profile Useful for Cell Line Authentication (2022) (1)
- Clusterin Plasma Concentrations Are Decreased in Sepsis and Inversely Correlated with Established Markers of Inflammation (2022) (1)
- Investigation of soluble anti-Müllerian hormone receptor type 2 as a biomarker for diagnosis of female fertility disorders. (2019) (1)
- Rapid FSAP Genotyping of the E393Q (Marburg II) and G534E (Marburg I) Polymorphisms on the LightCycler in a Multiplex PCR Using Two Fluorescently Labeled Probe Sets (2008) (1)
- Faculty Opinions recommendation of In vitro and in vivo gene therapy vector evolution via multispecies interbreeding and retargeting of adeno-associated viruses. (2008) (1)
- [247] CIRCULATING RETINOL BINDING PROTEIN 4 IS REDUCED IN LIVER CIRRHOSIS AND NOT ASSOCIATED WITH INSULIN RESISTANCE (2007) (1)
- Pro-Angiogenic and Antimesangioproliferative Effects (2012) (1)
- 969 CYCLIN E1 CONTROLS THE CELL CYCLE ACTIVITY OF HEPATIC STELLATE CELLS AND TRIGGERS FIBROGENESIS IN MICE (2010) (1)
- A new free light chain immunoassay shows advantages in the classification and in the follow-up of patients with paraproteinemia compared to a nephelometric assay (2019) (1)
- Neue pathogenetische Konzepte der Leberfibrose mit Optionen für Therapie und Diagnostik (2007) (1)
- Immunohistochemical Detection of Estrogen Receptor-Beta (ERβ) with PPZ0506 Antibody in Murine Tissue: From Pitfalls to Optimization (2022) (1)
- Faculty Opinions recommendation of Diagnostic considerations for cholestatic liver disease. (2018) (0)
- Y-box-binding protein (YB-1) in murine models of hepatic and renal fibrosis (2015) (0)
- Model of a TGF-β1-induced tumor-promoting signaling pathway in HepG2 cells (2020) (0)
- 962 HEPATIC ENDOGLIN EXPRESSION IS UPREGULATED DURING TRANSDIFFERENTIATION OF HSC TO MFB AND MODULATES PROFIBROGENIC RESPONSES IN MYOFIBROBLAST-LIKE CELLS (2010) (0)
- Faculty Opinions recommendation of Recent Insights into the Pathogenesis of Nonalcoholic Fatty Liver Disease. (2018) (0)
- Interview with Prof. Ralf Weiskirchen: challenges and opportunities in gastroenterology and hepatology (2022) (0)
- Faculty Opinions recommendation of TEMPORARY REMOVAL: CD271 identifies functional human hepatic stellate cells, which localize in peri-sinusoidal and portal areas in liver after partial hepatectomy. (2014) (0)
- Apoptosis sensitization of hepatocytes by acyl-CoA synthetase 5 involves deregulation of sphingolipid metabolism and alterations in mitochondrial signalling (2011) (0)
- Editorial: Inflammation and Fibrosis in the Gastrointestinal Tract and Liver: Mechanisms and Targets (2021) (0)
- Faculty Opinions recommendation of norUrsodeoxycholic acid improves cholestasis in primary sclerosing cholangitis. (2018) (0)
- Faculty Opinions recommendation of Casticin attenuates liver fibrosis and hepatic stellate cell activation by blocking TGF-β/Smad signaling pathway. (2017) (0)
- Expression profile and functional activity of Platelet-derived growth factor-C and -D in bile duct-ligated rat livers and transdifferentiating hepatic stellate cells (2007) (0)
- PLGA-Nanospheres: Delivery tools for the treatment of liver fibrosis (2006) (0)
- TRAIL and TNFR1-dependent pathways and their role for progression of Nemo-dependent hepatitis (2011) (0)
- Expression analysis of inflammasomes in experimental models of inflammatory and fibrotic liver disease (2012) (0)
- Commentary on: Physalin B attenuates liver fibrosis via suppressing LAP2α-HDAC1 mediated deacetylation of GLI1 and hepatic stellate cell activation (2021) (0)
- MALDI-MS analysis reveals reliable results in staging HCV induced fibrogenesis (2009) (0)
- Activation of latent TGF-β1 within the hepatocyte contributes to connective tissue growth factor (CTGF/CCN2) expression via entirely intracellular signalling (2007) (0)
- Faculty Opinions recommendation of Perilipin 5 restores the formation of lipid droplets in activated hepatic stellate cells and inhibits their activation. (2016) (0)
- The impact of multidrug resistance on tumor microenvironment remodelling and nanodrug delivery (2020) (0)
- 51 GENE POLYMORPHISMS WITHIN THE CODING REGION OF TGF-BETA1 AFFECT CELLULAR SYNTHESIS, SECRETION AND PROCESSING OF TGF-BETA1 VIA THE LATENT TGF-BETA BINDING PROTEIN-1 (LTBP-1) (2008) (0)
- CONSTITUTIVE ACTIVATION OF PDGFR-beta IN RENAL MESENCHYMAL CELLS DRIVES RENAL FIBROSIS (2016) (0)
- Regulation and profibrogenic effects of TGF-β1 signaling in mast cells, a cell type contributing to the outcome of hepatic injury (2015) (0)
- Isolation of Hepatocytes from Liver Tissue by a Novel, Semi-Automated Perfusion Technology (2022) (0)
- Faculty Opinions recommendation of Viral hepatitis and liver cancer. (2018) (0)
- Platelet-derived growth factor-D intensifies fibrogenesis through upregulation of TIMP-1 expression and signalling through both platelet-derived growth factor receptors type α and β (2015) (0)
- Functional analyses of the new hepatic stellate cell marker protein CRP2 (2000) (0)
- 137 TNF-RECEPTOR 1-DEPENDENT SIGNALLING DETERMINES THE PROGRESSION OF NEMO-MEDIATED HEPATITIS (2011) (0)
- Expression of the multiligand receptor Megalin in hepatic stellate cells (2005) (0)
- Deletion des Chemokins RANTES (CCL5) beeinflusst die Leberfibrose im Tiermodell durch eine vermehrte Induktion von Interleukin-10 (2008) (0)
- Faculty Opinions recommendation of Lipocalin-2 negatively modulates the epithelial-to-mesenchymal transition in hepatocellular carcinoma through the epidermal growth factor (TGF-beta1)/Lcn2/Twist1 pathway. (2013) (0)
- Faculty Opinions recommendation of Liver Disease in Alpha-1 Antitrypsin Deficiency: Current Approaches and Future Directions. (2018) (0)
- Lipocalin-2 (LCN2) in experimental liver injury and human liver diseases (2011) (0)
- Faculty Opinions recommendation of Inductive angiocrine signals from sinusoidal endothelium are required for liver regeneration. (2010) (0)
- 920 ANTIFIBROTIC PROPERTIES OF NOV/CCN3 IN LIVER (2010) (0)
- Defining the genetic characteristics of human hepatic stellate cell line LX-2 by spectral karyotyping and short tandem repeat genotyping (2013) (0)
- Endoglin modulates Smad-dependent and Smad-independent pathways to regulate proliferation, migration and profibrogenic responses in myofibroblasts (2010) (0)
- Expression and Function of Four-and-a-Half LIM-domain protein 2 (FHL2) in Hepatic Fibrosis (2020) (0)
- Letter to the Editor: LO2, a misidentified cell line: Some data should be interpreted with caution. (2022) (0)
- Elevated MR-proANP plasma concentrations are associated with sepsis and predict mortality in critically ill patients (2019) (0)
- Antigen-presenting function of rat hepatic stellate cells (2007) (0)
- Faculty Opinions recommendation of Enoxaparin reduces hepatic vascular resistance and portal pressure in cirrhotic rats. (2018) (0)
- Faculty Opinions recommendation of Diet-Induced Rat Model of Gradual Development of Non-Alcoholic Fatty Liver Disease (NAFLD) with Lipopolysaccharides (LPS) Secretion. (2019) (0)
- Faculty Opinions recommendation of Gut Microbiome-Based Metagenomic Signature for Non-invasive Detection of Advanced Fibrosis in Human Nonalcoholic Fatty Liver Disease. (2018) (0)
- The bile acid phospholipid conjugate ursodeoxycholate lysophoshatidylethanolamide acts by binding to calcium independent membrane phospholipase A2 type beta (2021) (0)
- Faculty Opinions recommendation of The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance. (2011) (0)
- Characterization of TGF-β-dependent signaling-pathways for CTGF/CCN2 expression in hepatocytes of normal and injured livers (2007) (0)
- Adenoviral expression of the Nephroblastoma overexpressed gene product (CCN3/NOV) induces apoptosis and inhibits epithelial-to-mesenchymal transition (EMT) in hepatocytes in vitro but fails to attenuate ongoing liver fibrogenesis in vivo (2012) (0)
- Spotlight on liver macrophages for halting liver disease progression and injury (2022) (0)
- Additional file 1: of ITIH5 mediates epigenetic reprogramming of breast cancer cells (2017) (0)
- Additional file 6: of ITIH5 mediates epigenetic reprogramming of breast cancer cells (2017) (0)
- TGF-β1 mediated Smad1/Smad5 signalling modulates transdifferentiation of hepatic stellate cells (2009) (0)
- Faculty Opinions recommendation of Wilson's Disease in Finland: A Nationwide Population-Based Study. (2020) (0)
- TNF-receptor 1 ameliorates disease progression of Nemo-mediated hepatitis (2011) (0)
- The CSRP2-Promoter: A Tool for Transcriptional Targeting of Hepatic Stellate Cells During Liver Fibrogenesis? (2005) (0)
- Transforming Growth Factor-β induced Expression of Serum Response Factor in Hepatic Stellate Cells during Liver Fibrogenesis (2007) (0)
- Endoglin is upregulated and counteracts profibrogenic responses in transdifferentiating hepatic stellate cells (2010) (0)
- Non-invasive diagnosis and assessment of patients with chronic hepatitis C (CHC): The importance of serum proteome profiling with SELDI-TOF-MS – preliminary results (2006) (0)
- Lipocalin 2 (LCN2) in hepatic inflammation (2015) (0)
- Faculty Opinions recommendation of Structure-Activity Relationship of Aloperine Derivatives as New Anti-Liver Fibrogenic Agents. (2020) (0)
- Expression of smooth muscle cell markers in activated hepatic stellate cells is connected to MAP kinase regulated transcription levels of serum response factor (SRF) (2009) (0)
- Cover Image, Volume 70, Issue 11 (2022) (0)
- Faculty Opinions recommendation of Restoration of a healthy intestinal microbiota normalizes portal hypertension in a rat model of nonalcoholic steatohepatitis. (2018) (0)
- Potential novel diagnostic applications of laser ablation inductively coupled plasma mass spectrometry in trace metal imaging of hepatic metal disorders (2014) (0)
- Additional file 7: of ITIH5 mediates epigenetic reprogramming of breast cancer cells (2017) (0)
- Faculty Opinions recommendation of Matricellular protein CCN1 promotes regression of liver fibrosis through induction of cellular senescence in hepatic myofibroblasts. (2013) (0)
- Faculty Opinions recommendation of Non-Canonical Wnt Predominates in Activated Rat Hepatic Stellate Cells, Influencing HSC Survival and Paracrine Stimulation of Kupffer Cells. (2015) (0)
- Editorial: Insights in Gastrointestinal and Hepatic Pharmacology: 2021 (2022) (0)
- Transdifferentiation-dependent expression of distinct C5a-receptors C5R1 and C5L2 in cultured hepatic stellate cells and their response to C5a-ligand (2006) (0)
- Additional file 3: of ITIH5 mediates epigenetic reprogramming of breast cancer cells (2017) (0)
- The impact of the reactive oxygen species scavenger N-acetyl-L-cysteine for PDGF-BB signaling in cultured hepatic stellate cells (2006) (0)
- Inhibition of C-C motif chemokine receptor 2 (CCR2) using a novel in silico designed peptide attenuates macrophage migration in vitro and intrahepatic monocyte recruitment in vivo (2022) (0)
- Faculty Opinions recommendation of Fructose and sugar: A major mediator of non-alcoholic fatty liver disease. (2018) (0)
- Antifibrotic effects of CCN1/CYR61 in primary portal myofibroblasts through induction of reactive oxygen species and resulting apoptosis (2014) (0)
- Commentary: Crocetin protected human hepatocyte LO2 cell from TGF-β-induced oxygen stress and apoptosis but promoted proliferation and autophagy via AMPK/m-TOR pathway (2022) (0)
- Molecular details on BMP-7 activity on TGF-beta1-mediated CTGF expression in myofibroblasts (2011) (0)
- [453] ASSOCIATION OF CCBP2, A SCAVENGER RECEPTOR FOR INFLAMMATORY CC CHEMOKINES, WITH LIVER INFLAMMATION IN MICE AND HUMANS (2007) (0)
- The platelet-derived chemokine CXCL4 mediates experimental liver fibrosis and is associated with HCV and NASH induced fibrosis (2010) (0)
- Synergism between Jnk1 and Jnk2 is a sine qua non condition for hepatic protection against toxicity (2014) (0)
- Hepatic Proteome and Lipid Profiling of Wild Type and Lipocalin-2-Deficient Mice in Experimental Steatosis (2015) (0)
- AMINO-TERMINAL LIM DOMAIN FROM QUAIL CYSTEINE AND GLYCINE-RICH PROTEIN, NMR, MINIMIZED AVERAGE STRUCTURE (1998) (0)
- Lipocalin 2 attenuates oligodendrocyte loss and immune cell infiltration in mouse models for multiple sclerosis (2022) (0)
- The fraktalkine receptor CX3CR1 is associated with progression of liver fibrosis in patients with chronic hepatitis C (2006) (0)
- Primary peritoneal mast cells (PMC) reduce the fibrogenic response of hepatic stellate cells while inducing caspase 3 cleavage and activity (2016) (0)
- Additional file 4: of ITIH5 mediates epigenetic reprogramming of breast cancer cells (2017) (0)
- Faculty Opinions recommendation of Global prevalence, treatment, and prevention of hepatitis B virus infection in 2016: a modelling study. (2018) (0)
- TGF-β induced upregulation of CRP2 and SRF in activated hepatic stellate cells–Involvement in smooth muscle gene expression during liver fibrogenesis? (2006) (0)
- Faculty Opinions recommendation of Hydatid cyst fluid promotes peri-cystic fibrosis in cystic echinococcosis by suppressing miR-19 expression. (2018) (0)
- Faculty Opinions recommendation of Effect of reversine on cell cycle, apoptosis, and activation of hepatic stellate cells. (2016) (0)
- Upregulation of human acyl-CoA synthetase 5 in fatty liver degeneration sensitizes for hepatocellular apoptosis (2009) (0)
- New pathogenetic concepts of liver fibrosis with options for therapy and diagnostics (2007) (0)
- Caspase-8 deficiency ameliorates hepatic steatosis, but not apoptosis, in a murine model of alcoholic liver disease (2017) (0)
- Differential regulation of Id1 expression by TGF-β1 in HepG2 cells (2014) (0)
- Erratum to “Proteomic tissue profiling for the improvement of grading of noninvasive papillary urothelial neoplasia” [Clinical Biochemistry 45 (2012) 7–11] (2012) (0)
- A Beginner’s Guide to Cell Culture: Practical Advice for Preventing Needless Problems (2023) (0)
- The Cape Gooseberry Constituent Physalin B Ameliorates Nonalcoholic Steatohepatitis and Attenuates Liver Fibrosis (2021) (0)
- Hepatic nephroblastoma overexpressed (NOV/CCN3) in experimental liver fibrosis models (2009) (0)
- The pathogenesis of hepatic fibrosis: basic facts and clinical challenges (2021) (0)
- The selective induction of apoptosis in HSC by the targeted thymidine kinase/Ganciclovir system (2008) (0)
- Untersuchung von antigenpräsentierenden Funktionen bei kultivierten hepatischen Sternzellen und transdifferenzierenden Myofibroblasten der Ratte (2010) (0)
- Endoglin and its involvement in transdifferentiation of hepatic stellate cells (2007) (0)
- Latent transforming growth factor-A binding protein-1 (LTBP) knockout - A tool for better understanding of liver fibrosis progression? (2005) (0)
- Quantification of hepatic liver iron overload with laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) (2019) (0)
- The impact of TGF-β and S1P on the cellular localization of the LIM domain proteins CRP2 and FHL2 in LX-2 cells (2010) (0)
- Interleukin-8 korreliert mit dem Schweregrad der Leberfibrose und –zirrhose und ist insbesondere assoziert mit cholestastischen Leberkrankungen (2011) (0)
- The Beatles in life sciences: Facts and fictions (2022) (0)
- [Efficacy of enteric lecithin (phosphatidylcholine) in the treatment of ulcerative colitis: a meta-analysis]. (2022) (0)
- Faculty Opinions recommendation of Current and upcoming pharmacotherapy for non-alcoholic fatty liver disease. (2018) (0)
- Faculty Opinions recommendation of Therapeutic strategies for alcoholic liver disease: Focusing on inflammation and fibrosis (Review). (2018) (0)
- Faculty Opinions recommendation of Mitochondrial uncouplers inhibit hepatic stellate cell activation. (2012) (0)
- The Role of Cow’s Milk Consumption in Breast Cancer Initiation and Progression (2023) (0)
- Faculty Opinions recommendation of Current and future pharmacological therapies for NAFLD/NASH. (2018) (0)
- Lipid-Independent Regulation of PLIN5 via IL-6 through the JAK/STAT3 Axis in Hep3B Cells (2023) (0)
- Faculty Opinions recommendation of Senescence of activated stellate cells limits liver fibrosis. (2008) (0)
- Faculty Opinions recommendation of Perivenous stellate cells are the main source of myofibroblasts and cancer-associated-fibroblasts formed after chronic liver injuries. (2021) (0)
- 3R Blackboard: A platform for animal and organ sharing (2022) (0)
- Lipocalin-2 (LCN2) expression during transdifferentiation of rat hepatic stellate cells and its potential impact on liver fibrogenesis (2009) (0)
- Novel therapeutic targets in liver pathology: From basic science to clinical translation (2022) (0)
- Lipocalin 2 in perpetuating hepatic lipid homeostasis challenged by high fructose diet (2020) (0)
- Hepatic Fibrogenesis (2020) (0)
- MUTANT R122A OF QUAIL CYSTEINE AND GLYCINE-RICH PROTEIN, NMR, MINIMIZED STRUCTURE (1999) (0)
- Secreted Frizzled Related Protein 5 (SFRP5) Serum Levels Are Decreased in Critical Illness and Sepsis and Are Associated with Short-Term Mortality (2023) (0)
- Faculty Opinions recommendation of Telbivudine versus lamivudine in patients with chronic hepatitis B. (2008) (0)
- Faculty Opinions recommendation of Hepatic metabolism of retinoids and disease associations. (2011) (0)
- TGF-β1 modulates LPS-induced NLRP3 inflammasome activity (2014) (0)
- Faculty of 1000 evaluation for Synectin promotes fibrogenesis by regulating PDGFR isoforms through distinct mechanisms. (2018) (0)
- Faculty Opinions recommendation of Selective targeting of lysyl oxidase-like 2 (LOXL2) suppresses hepatic fibrosis progression and accelerates its reversal. (2018) (0)
- Saturated phosphatidylcholine as dietary additive for colonic mucus: an open label prospective clinical observation trial (2021) (0)
- Identification of the N-Acetylcysteine Sensitive Receptor Endoglin in Hepatic Stellate Cells (2005) (0)
- Experimental pathology - 1 (2009) (0)
- Editorial: Macrophages in Liver Disease (2020) (0)
- Adiponectin as a modulator of hepatic fibrosis in chronic HCV-Infection (2007) (0)
- False Negative Results in Testing for Drugs of Abuse from Diluted Urine (2017) (0)
- Copy number variation of the CCL3L1 gene in chronic HCV infection: Influence on susceptibility and fibro-inflammatory response (2007) (0)
- Chronic mineral oil administration increases hepatic inflammation in wild type mice compared to lipocalin 2 null mice (2021) (0)
- Faculty Opinions recommendation of A rapid and sensitive bioassay to measure bone morphogenetic protein activity. (2007) (0)
- P593 ANTIFIBROTIC EFFECTS OF CCN1/CYR61 ARE MEDIATED THROUGH INDUCTION OF REACTIVE OXYGEN SPECIES RESULTING IN PMF AND HSC APOPTOSIS AND ATTENUATED TGF BETA SIGNALLING (2014) (0)
- Effects of asparaginases and L-carnitine on Western-diet-induced hepatosteatosis in mice (2022) (0)
- Molecular details of BMP-7 signaling in hepatic stellate cells and myofibroblasts (2010) (0)
- Expression analysis of CCN1/CYR61 in primary liver cells and in models of experimental liver fibrogenesis (2013) (0)
- Der sternzellspezifische Multiligandenrezeptor Megalin wird während der frühen Transdifferenzierung hepatischer Sternzellen und der experimentellen Fibrogenese in vivo verstärkt exprimiert (2005) (0)
- PDGF isoform expression in carbon tetrachloride induced chronic liver injury (2008) (0)
- Antagonization of TIMP–1 Induces Apoptosis in Activated Hepatic Stellate Cells (2005) (0)
- Analytical Detection of Prenatal Drug Exposure in Early Childhood in Prenatal, Perinatal and Postnatal Matrices (2022) (0)
- Faculty Opinions recommendation of Single-Cell Transcriptomics Reveals Early Emergence of Liver Parenchymal and Non-parenchymal Cell Lineages. (2020) (0)
- Blockade of NLRP3 expression in primary hepatocytes by inhibitors of NF-κB signalling (2014) (0)
- 999 HUMAN MONOCYTE SUBSETS ACCUMULATE INTRAHEPATICALLY IN LIVER CIRRHOSIS AND DIFFERENTIALLY INTERACT WITH HEPATIC STELLATE CELLS (2010) (0)
- The absence of latent transforming growth factor-beta binding protein–1 (LTBP–1) inhibits TGF-beta secretion (2008) (0)
- Faculty Opinions recommendation of Gap junction inhibition prevents drug-induced liver toxicity and fulminant hepatic failure. (2012) (0)
- Hepatic stellate cell specific endoglin deletion modulates TGF-β signaling and aggravates liver fibrosis in two experimental models of murine liver injury (2014) (0)
- Learning more about the role of Latent transforming growth factor-β binding protein–1 (LTBP–1) – a knockout approach in mice (2006) (0)
- Molecular imaging of Cyclin E1 represents an indicator of acute and chronic liver disease (2015) (0)
- Faculty Opinions recommendation of Enoxaparin does not ameliorate liver fibrosis or portal hypertension in rats with advanced cirrhosis. (2018) (0)
- Synergistic effects of Platelet-derived growth factor-BB and Transforming growth factor-β1 on profibrogenic activities in hepatic stellate cells (2008) (0)
- Diversity of TGF-β-signaling in rat hepatic stellate cells and in myofibroblasts (2006) (0)
- Upregulation of smooth muscle cell markers in activated hepatic stellate cells is mediated by serum response factor (2007) (0)
- Faculty Opinions recommendation of Autoantibodies in Autoimmune Hepatitis: Can Epitopes Tell Us about the Etiology of the Disease? (2018) (0)
- Hepatic stellate cells down-regulate pro-apoptotic effector abundance and secretion in mast cells (2016) (0)
- Expression and TGF-beta modulation of connective tissue growth factor (CTGF) in hepatic stellate cells and hepatocytes (2006) (0)
- Lipocalin 2 (LCN2) in experimental liver injury (2010) (0)
- [Diagnostic value of the quantitative HBsAg determination in hepatitis B infections]. (2016) (0)
- THU-370-Quantification of hepatic metal overload by laser ablation inductively coupled plasma mass spectrometry imaging (LA-ICP-MSI) (2019) (0)
- Establishment of novel innovative bioimaging techniques of metals by laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) for diagnosis of liver damage (2013) (0)
- ITIH5 mediates epigenetic reprogramming of breast cancer cells (2017) (0)
- 136 ENDOGLIN DEFICIENCY IN HEPATIC STELLATE CELLS HAS A DIFFERENTIAL EFFECT ON LIVER FIBROSIS AND TGF-b SIGNALLING IN TWO EXPERIMENTAL MODELS OF MURINE LIVER FIBROSIS (2013) (0)
- Additional file 2: of ITIH5 mediates epigenetic reprogramming of breast cancer cells (2017) (0)
- Transformation of primary murine peritoneal mast cells by constitutive KIT activation as a result of lost Cdkn2a/Arf expression (2023) (0)
- Deletion of the platelet derived chemokine PF4 (CXCL4) limits liver fibrosis in vivo (2009) (0)
- Transcriptional Targeting of Activated Hepatic Stellate Cells by Modular Promoter Fragments (2008) (0)
- Role of NOV and CTGF in PDGF and TGF-β signaling in hepatic fibrogenesis (2010) (0)
- Evidence for a heterodimeric structure of megalin in liver macrophages (2012) (0)
- Established Hepatic Stellate Cell Lines in Hepatology Research (2023) (0)
- Faculty Opinions recommendation of Myofibroblastic cells function as progenitors to regenerate murine livers after partial hepatectomy. (2013) (0)
- Overwhelming high quantities of the matricellular protein CCN1/CYR61 induce ER stress-related cellular apoptosis in hepatic stellate cells (2015) (0)
- Impact of soluble Endoglin on TGF-β1 mediated immediate early responses in HepG2 cells (2014) (0)
- The CYR61/CTGF/NOV (CCN) family members induce endoplasmic reticulum stress and unfolded protein response (2016) (0)
- Lipocalin 2 (LCN2)-deficient mice are more prone to hepatic steatosis: LCN2 and mitochondrial and peroxisomal integrity (2016) (0)
- The „accessory“ TGF-β pathway is not obligatory to ALK1 expressing cells (2006) (0)
- Faculty Opinions recommendation of Epidemiology of hepatitis B virus (HBV) and hepatitis C virus (HCV) related hepatocellular carcinoma. (2018) (0)
- Supplemental Material 5 MAKERGAUL : An innovative MAK 2-based model and software for real-time PCR quantification (2013) (0)
- Transkriptionelles targeting hepatischer Sternzellen durch Einsatz Zell-spezifischer Promotoren in adenoviralen Systemen (2004) (0)
- Kryokonservierung von hepatischen Sternzellen der Ratte (2007) (0)
- Untersuchung von Lipocalin 2 und Perilipin 5 in der Fruktose-induzierten Nichtalkoholischen Fettlebererkrankung (2016) (0)
- Assoziation von CCBP2, einem Scavenger-Rezeptor für inflammatorische Chemokine, mit der Leberentzündung im Tiermodell und bei Patienten mit chronischer Hepatitis C (2007) (0)
- Funktionelle Interaktion der Chemokine CCL5 (RANTES) und CXCL4 (PF4) im Tiermodell und bei Patienten mit chronischen Lebererkrankungen (2007) (0)
- Fetuin-B inhibiert die frühzeitige Zona Pellucida Härtung und erhält so die Fertilität (2014) (0)
- Regulation von Transaktivierungsmarkern einer etablierten HSC-Linie durch Applikation von Fettsäuren (2009) (0)
- Proteolytisch inaktive MMP-9 Mutanten induzieren Apoptose in Hepatischen Sternzellen (2008) (0)
- Expression, Reinigung und quantitative in vitro Charakterisierung proteolytisch inaktiver MMP-9-Mutanten als TIMP-1 Antagonisten (2004) (0)
- DIGE (Difference In Gel Electrophoresis) Analyse von BALB-Abcb4-/- Mäusen zeigt eine verminderte Expression von Selenium binding protein 2 in der Leber (2006) (0)
- Die PDGF-BB-vermittelte Stimulation Hepatischer Sternzellen wird in vitro durch die Plasmaprotease FSAP (Faktor VII Aktivierende Protease) inhibiert (2008) (0)
- Der Multiligandenrezeptor Megalin–ein neuer Marker für hepatische Sternzellen (2004) (0)
- Regulation der Expression von Lipocalin-2 in der Leberzelllinie HepG2 durch die Zytokine IL-6 und IL-1β (2018) (0)
- Der Komplementfaktor 5 (C5) beeinflusst die Fibrose-Suszeptibilität im Inzuchtmausmodell (2015) (0)
- Die genetische Deletion des von Thrombozyten sezernierten Chemokins PF4 (CXCL4) reduziert die Leberfibrose in vivo (2009) (0)
- Effekt von Endoglin auf die Differenzierung und das Signalling in einer neuen Col-GFP-exprimierenden immortalisierten murinen Sternzell-Linie (2013) (0)
- Lipocalin 2 und Perilipin 5 in der Pathogenese der durch Fruktose ausgelösten NAFLD (2015) (0)
- Leber-Fibrose: Erstellung eines Modells zur Analyse lebertoxischer Substanzen und Analyse der ltbp1-abhängigen Aktivierung hepatischer Sternzellen (2006) (0)
- Wirksamkeit von darmlöslichem Lecithin (Phosphatidylcholin) zur Behandlung der Colitis ulcerosa (2022) (0)
- Diagnostischer Wert der quantitativen HBsAg-Bestimmung bei der Hepatitis B-Infektion (2016) (0)
- In vivo Nachweis apoptotischer Hepatischer Sternzellen als Ursache der antifibrotischen Wirkung von TIMP–1 Antagonisten (2006) (0)
- Zell- und molekularbiologische Untersuchungen eines EPO-mimetischen Peptides während der präklinischen Phase der Arzneimittelentwicklung (2010) (0)
- Maternale und fetale Thrombophilien (Faktor-V-Leiden-Mutation G1691A; Methylterahydrofolatreduktase-Mutation C677T; Prothrombin-Mutation G20210A) zeigen keine Assoziation zum Auftritt eines HELLP-Syndroms (2004) (0)
- Bedeutung der Chemokine CCL5 (RANTES) und CXCL4 (PF4) bei Patienten mit chronischen Lebererkrankungen (2007) (0)
- Erfolgreiche Fibrosetherapie mittels proteolytisch inaktiver MMP–9 Mutanten: ein gentherapeutischer Ansatz (2004) (0)
- Verbesserung der Labordiagnostik durch Leistungsbewertungsprüfung und klinische Validierung von Immunoassays für Infektionsserologie und Endokrinologie (2018) (0)
- Pharmakologische Hemmung des Chemokins MCP-1 in der Regression der experimentellen Leberfibrose in Mausmodellen (2017) (0)
- Signalwege der glomerulären Nierenschädigung (2017) (0)
- Transdifferenzierungsabhängige Expression von Spleißvarianten des Transkriptionsfaktors „Serum Response Factor“ in aktivierten hepatischen Sternzellen (2008) (0)
- TNFα behandelte primäre triple-negative Brustkrebs-Stammzellen werden invasiv und induzieren vaskuläre Neubildung in der Leber – Hinweise auf die Seed&Soil Theorie (2022) (0)
- Einfluss von Transforming Growth Factor-beta1 (TGF-[beta]1) Genpolymorphismen auf die Hepatitis-C-induzierte Leberfibrose in vivo und Modulation der TGF-[beta]1-Synthese, Prozessierung und Sekretion durch die Serin-Protease Furin, das latent TGF-[beta] binding protein-1 und Polymorphismen der TGF-[b (2008) (0)
- Auftreten der Gln223Arg-Mutation im Gen des Leptinrezeptors und der Pro12Ala Mutation im Gen des PPARγ bei Patienten mit chronischer Hepatitis C (2007) (0)
- Charakterisierung des BMP-7-Signalwegs und der TGF-beta-1-BMP-7-Wechselwirkungen in myofibroblasten-ähnlichen Zellen (2011) (0)
- Verminderte Transgenexpression nach adenoviralem Gentransfer in experimentell geschädigten Rattenlebern (2005) (0)
- Induzierter Zelltod von transdifferenzierten hepatischen Sternzellen (Myofibroblasten) auf der Basis des Thymidinkinase-Ganciclovir-Systems (2007) (0)
- Expression and function of S-endoglin, a rat specific splice variant of endoglin, in liver cells (2011) (0)
- Neue Therapieoptionen für die Leberfibrose (2015) (0)
- Selenium Binding Protein 2 zeigt eine verminderte Expression in fibrotischer Leber: Ergebnisse einer Difference In Gel Electrophoresis (DIGE)-Analyse (2005) (0)
- Faculty of 1000 evaluation for A Roadmap for Human Liver Differentiation from Pluripotent Stem Cells. (2018) (0)
- O145 THE REGULATORY INTERPLAY BETWEEN JNK1 AND JNK2 IS A SINE QUA NON CONDITION AGAINST DRUG-INDUCED LIVER TOXICITY (2014) (0)
- Optimization purity of isolated primary liver endothelial cells (LSEC) using adenoviral gene transfer (2014) (0)
- SP277CONSTITUTIVE ACTIVATION OF PDGFR-β IN RENAL MESENCHYMAL CELLS DRIVES RENAL FIBROSIS (2016) (0)
- Analysis of transforming growth factor-β1 gene polymorphisms in patients with Hepatitis C infection (2006) (0)
- Faculty Opinions recommendation of Lipocalin 2 induces neuroinflammation and blood-brain barrier dysfunction through liver-brain axis in murine model of nonalcoholic steatohepatitis. (2020) (0)
- Adiponectin as a putative modulator of hepatitis in chronic HCV-infection (2007) (0)
- Mast cells inhibit activation and profibrogenic activities of hepatic stellate cells (2015) (0)
- Effects of N-acetylcysteine and L-Cysteine on TGF-beta Signaling in Culture-activated Hepatic Stellate Cells (2004) (0)
- Inactivation of Cyclin E1 acts pro-apoptotic and anti-proliferative in primary hepatoma cells and protects from hepatocarcinogenesis in mice (2015) (0)
- NLRP3 inflammasome expression in cultured hepatocytes is regulated by nuclear factor-κB (NF-κB) (2015) (0)
- Wilson disease: more complex than just simply a copper overload condition?—a narrative review (2022) (0)
- Faculty Opinions recommendation of Fecal microbiota manipulation prevents dysbiosis and alcohol-induced liver injury in mice. (2018) (0)
- Faculty Opinions recommendation of Cryptogenic cirrhosis and sitosterolemia: A treatable disease if identified but fatal if missed. (2018) (0)
- Gene polymorphisms in the secretory signal peptide of TGF-β1 affect the cellular synthesis, secretion and processing of TGF-β1 and secretion is modulated by the latent TGF-β binding protein-1 (LTBP-1) and furin protease (2007) (0)
- P0427 : Platelet-derived growth factor-D intensifies fibrogenesis through upregulation of TIMP-1 and signaling via both platelet-derived growth factor receptor type alpha and beta (2015) (0)
- Transcriptional activity of Serum Response Factor is mediated by the RhoA/Rho kinase pathway during HSC differentiation and influences expression of Smooth Muscle Cell marker genes (2008) (0)
- Combined analysis of microRNA and mRNA signatures in human hematopoietic stem and progenitor cells using a novel microarray quantification system (2011) (0)
- Additional file 8: of ITIH5 mediates epigenetic reprogramming of breast cancer cells (2017) (0)
- Modulation of intracellular TGF-beta signalling by different PDGF isoforms and MEK1/2 in a murine hepatic stellate cell line (2011) (0)
- Personalized medicine in hepatitis C: From genome‐wide association studies to clinical practice (2010) (0)
- Faculty Opinions recommendation of Diagnostic autoantibodies for autoimmune liver diseases. (2018) (0)
- Mammalian plasma fetuin-B is a selective inhibitor of ovastacin and meprin metalloproteinases (2019) (0)
- QUAIL CYSTEINE AND GLYCINE-RICH PROTEIN, NMR, MINIMIZED AVERAGE STRUCTURE (1997) (0)
- Transformation of primary murine peritoneal mast cells by constitutive KIT activation is accompanied by loss of Cdkn2a/Arf expression (2023) (0)
- Additional file 5: of ITIH5 mediates epigenetic reprogramming of breast cancer cells (2017) (0)
- TIMP-1 überexprimierende Leberzellen zeigen mittels DIGE-Technologie ein verändertes Proteinmuster mit Fibrose-relevanten Proteinen (2004) (0)
- Scavenging endogenous PDGF B-chain by adenovirus-mediated PDGFbetaR-Fc gene transfer potentially inhibits HSC activation and attenuates liver fibrosis (2004) (0)
- The megalin/gp330 receptor is involved in the capability of hepatic stellate cells to bind and internalize vitamin D binding protein (Gc-globulin) (2008) (0)
- Differentiation and effects of TGF-β1 and IL-3 signaling on primary murine endoglin deficient mast cells (2016) (0)
- More than a serum parameter: Functional relevance of soluble endoglin (solEng) (2012) (0)
- LIM-domain protein CRP2 is upregulated in activated hepatic stellate cells by TGFβ1 (2005) (0)
- Evaluation of Arginine-Nitric Oxide Pathway in Patients with Hyperthyroidism (2021) (0)
- Does it matter not only how much but also when we eat to induce fatty liver? (2011) (0)
- Editorial for focused issue "Wilson Disease: From Genetics to Management of Disease". (2019) (0)
- MALDI-TOF mass spectrometry of serum as a promising diagnostic technique to analyze the severity and progression of fibrogenesis in patients suffering from chronic Hepatitis C infection (2008) (0)
- 重组大鼠TGF-β1在大肠杆菌的表达及初步鉴定 (2001) (0)
- Faculty Opinions recommendation of Lipocalin 2 drives neutrophilic inflammation in alcoholic liver disease. (2016) (0)
- Faculty Opinions recommendation of Montelukast Prevents Mice Against Acetaminophen-Induced Liver Injury. (2019) (0)
- Accurate standardization and normalization of hepatic metal contents in Laser Ablation Inductively Coupled Plasma Mass Spectrometry (LA-ICP-MS) (2016) (0)
- Lipocalin 2, an essential multi-regulator of hepatic homeostasis during a Methionine Choline deficient diet-induced non-alcoholic steatohepatitis in mice (2015) (0)
- 491 THE BMP-7 PATHWAY IN HEPATIC STELLATE CELLS AND HEPATOCYTES AND ITS ANTAGONISTIC EFFECT ON THE TGF-BETA1 SIGNALING PATHWAY (2008) (0)
- The N-Acetylcysteine sensitive TGF-β receptor endoglin shows a defined expression pattern in liver cells (2005) (0)
- The knockout of latent transforming growth factor-β binding protein–1 (LTBP–1) affects the fibrogenic potential in mice liver (2007) (0)
- P0448 : Benefits of isolating HSC using fluorescence-based cell sorting (2015) (0)
- Faculty Opinions recommendation of A schistosome miRNA promotes host hepatic fibrosis by targeting transforming growth factor beta receptor III. (2019) (0)
- 283 A NON-REDUNDANT ROLE OF THE PLATELET-DERIVED CHEMOKINE CXCL4 (PF4) IN EXPERIMENTAL LIVER FIBROSIS (2009) (0)
- Transiente Proliferation und Aktivierung Hepatischer Sternzellen im Maus-Modell der Thioacetamid induzierten Fibrose (2007) (0)
- Potential Pathogenic Impact of Cow’s Milk Consumption and Bovine Milk-Derived Exosomal MicroRNAs in Diffuse Large B-Cell Lymphoma (2023) (0)
- Cold traps as reliable devices for quantitative determination of SARS-CoV-2 load in aerosols (2021) (0)
- Contribution of E-type cyclins to hepatic fibrosis in human and mice (2010) (0)
- Unresolved basic issues in hepatology (2021) (0)
- Cyclin E1 is an essential pro-fibrotic factor in the liver (2010) (0)
- Bone morphogenetic protein–7 (BMP–7), a neglected player in hepatic fibrosis? (2007) (0)
- Faculty Opinions recommendation of Reference gene selection for real-time RT-PCR in eight kinds of rat regenerating hepatic cells. (2010) (0)
- Expression, Aufreinigung und Charakterisierung von rekombinantem hCTGF (CCN2) und rNOV (CCN3) in einem eukaryontischen Zellsystem (2010) (0)
- LCN2 null mice are sensitive to endoplasmic reticulum stress and unfolded protein responses (2019) (0)
- Cystatin C is expressed in hepatic stellate cells (HSC) and upregulated during transdifferentiation to myofibroblasts (MFB) (2005) (0)
- Faculty Opinions recommendation of Food components with antifibrotic activity and implications in prevention of liver disease. (2018) (0)
- Universal research index: An inclusive metric to quantify scientific research output (2023) (0)
- Expression of the cysteine protease inhibitor cystatin C in hepatic stellate cells is upregulated during transdifferentiation (2005) (0)
- Analysis of antigen-presenting functionality of rat hepatic stellate cells (2009) (0)
- Principle and workflow of LA-ICP-MS for hepatic metal imaging. (2013) (0)
- Intestinal Wnt in the transition from physiology to oncology (2022) (0)
- Quantification of chloride in sweat by using ion chromatography instead of chloridometer (2022) (0)
- Faculty Opinions recommendation of Identification of genes for hereditary hemochromatosis. (2018) (0)
- Faculty Opinions recommendation of Commensal microbiota is hepatoprotective and prevents liver fibrosis in mice. (2014) (0)
- Faculty Opinions recommendation of Matrix metalloproteinase-1 decorated polymersomes, a surface-active extracellular matrix therapeutic, potentiates collagen degradation and attenuates early liver fibrosis. (2021) (0)
- Faculty Opinions recommendation of Increased Expression of TGF-β1 in Correlation with Liver Fibrosis during Echinococcus granulosus Infection in Mice. (2018) (0)
- Corrigendum to “Factor VII activating protease (FSAP) exerts anti-inflammatory and anti-fibrotic effects in liver fibrosis in mice and men” [J Hepatol 2013;58:104–111] (2014) (0)
- TNFR1 controls apoptosis and chronic liver disease in hepatocyte-specific IKKγ (Nemo) mice. (2014) (0)
- Recombinant expression, purification and functional impact of CTGF/CCN2 and NOV/CCN3 on liver fibrogenesis (2011) (0)
- Cryopreservation of Hepatic Stellate Cells: A Valid Method for Banking Progenitor Cells of Liver Fibrogenesis (2005) (0)
- A new free light chain immunoassay shows better agreement with the quantification of the serum protein electrophoresis M-protein compared to a nephelometric assay in patients with multiple myeloma (2019) (0)
- The serum protein fetuin-b increases in vitro fertilization rate in mice by inhibiting premature zona pellucida hardening (2016) (0)
- Isolation of hepatocytes from various liver tissues by a novel, semi-automated perfusion technology (2022) (0)
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What Schools Are Affiliated With Ralf Weiskirchen?
Ralf Weiskirchen is affiliated with the following schools:
